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https://www.readbyqxmd.com/read/28108854/elective-icp-monitoring-how-long-is-long-enough
#1
S D Thompson, A Coutts, C L Craven, A K Toma, L W Thorne, L D Watkins
BACKGROUND: Intracranial pressure monitoring is commonly undertaken to assess and manage acute patients following head injury. However, ICP monitoring can also be a useful diagnostic tool in the management of CSF dynamics in elective patients. To date, there is little published research to suggest how long these elective patients require ICP monitoring in order to gain an accurate picture of a patient's ICP dynamics. At the author's institution, a minimum of 48-h data collection is currently undertaken in patients with a suspected ICP abnormality...
January 20, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28105089/laparoscopic-surgery-in-the-treatment-of-incarcerated-indirect-inguinal-hernia-in-children
#2
Yiyu Yin, Hongwei Zhang, Xiang Zhang, Fang Sun, Huaxin Zou, Hui Cao, Cheng Wen
We aimed to explore the feasibility and the safety of the laparoscopic surgery for incarcerated indirect inguinal hernia (IIH) in children. From January 2012 to December 2014, 64 children were enrolled into this study. All 64 patients received laparoscopic surgery and we reviewed their perioperative and postoperative follow-up studies. In addition, we enrolled 60 cases of children who received traditional surgery of IIH administered through minimally invasive surgery as the control group. Results from the present study showed that the mean operation time for the laparoscopic group was 41...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28088808/shunt-surgery-in-idiopathic-intracranial-hypertension-aided-by-electromagnetic-navigation
#3
Elvis J Hermann, Manolis Polemikos, Hans E Heissler, Joachim K Krauss
BACKGROUND: Idiopathic intracranial hypertension (IIH) is characterized by increased cerebrospinal fluid (CSF) pressure and normal or slit ventricles. Lumboperitoneal shunting had been favored by many investigators for CSF diversion in IIH for decades; however, it has been associated with various side effects. Because of the small ventricular size adequate positioning of a ventricular catheter is challenging. OBJECTIVES: Here, we investigated the usefulness of electromagnetic (EM)-guided ventricular catheter placement for ventriculoperitoneal shunting in IIH...
January 14, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28040526/the-effect-of-treatment-of-idiopathic-intracranial-hypertension-on-prevalence-of-retinal-and-choroidal-folds
#4
Mark J Kupersmith, Patrick A Sibony, Steven E Feldon, Jui-Kai Wang, Mona Garvin, Randy Kardon
PURPOSE: We described 3 types of folds in the retina and a crease in the outer retina associated with papilledema due to idiopathic intracranial hypertension (IIH) at presentation. We report the change in folds relative to treatment of IIH over the six months. Design/Study Subjects: Substudy of a randomized clinical trial. METHODS: Study eyes of subjects assigned to acetazolamide (ACZ, n=44) or placebo (PLB, n=43) had spectral domain optical coherence tomography (SDOCT) images of the optic disc and macula regions at baseline, 3 and 6 months...
December 28, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28017254/role-of-vitamin-a-metabolism-in-iih-results-from-the-idiopathic-intracranial-hypertension-treatment-trial
#5
J Libien, M J Kupersmith, W Blaner, M P McDermott, S Gao, Y Liu, J Corbett, M Wall
INTRODUCTION: Vitamin A and its metabolites (called retinoids) have been thought to play a role in the development of idiopathic intracranial hypertension (IIH). The IIH Treatment Trial (IIHTT) showed the efficacy of acetazolamide (ACZ) in improving visual field function, papilledema grade, quality of life and cerebrospinal fluid (CSF) pressure. We postulated that IIH patients would demonstrate elevated measures of vitamin A metabolites in the serum and CSF. METHODS: Comprehensive measures of serum vitamin A and its metabolites were obtained from 96 IIHTT subjects, randomly assigned to treatment with ACZ or placebo, and 25 controls with similar gender, age and body mass index (BMI)...
January 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28013373/an-update-on-idiopathic-intracranial-hypertension
#6
Mark Portelli, Panagiotis N Papageorgiou
BACKGROUND: Idiopathic intracranial hypertension (IIH) is still a grey area in the knowledge of the aetiology, diagnosis and management of neurosurgical diseases. The definition of IIH has been reviewed over time and many hypotheses have been expressed as cause of the disease. The literature supplies very little evidence-based information to guide our decision-making process when it comes to treat the disease. In this review we sum up the latest information regarding the aetiology and therapy of IIH...
December 24, 2016: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28009405/fulminant-idiopathic-intracranial-hypertension-and-venous-stasis-retinopathy-resulting-in-severe-bilateral-visual-impairment
#7
Alexander Voldman, Breanna Durbin, John Nguyen, Brian Ellis, Monique Leys
PURPOSE: To report a complicated case of fulminant idiopathic intracranial hypertension and concomitant venous stasis retinopathy leading to postpapilledema optic atrophy. METHODS: Case report. RESULTS: A 34-year-old morbidly obese woman with a history of idiopathic intracranial hypertension (IIH) presented with a 1-month history of bilateral vision loss, diplopia, and left eye pain after being lost to follow-up for 6 years. Fundus examination revealed florid papilledema with venous tortuosity bilaterally...
December 6, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28009240/venous-sinus-stenting-for-reduction-of-intracranial-pressure-in-iih-a-prospective-pilot-study
#8
Kenneth C Liu, Robert M Starke, Christopher R Durst, Tony R Wang, Dale Ding, R Webster Crowley, Steven A Newman
OBJECTIVE Idiopathic intracranial hypertension (IIH) may cause blindness due to elevated intracranial pressure (ICP). Venous sinus stenosis has been identified in select patients, leading to stenting as a potential treatment, but its effects on global ICP have not been completely defined. The purpose of this pilot study was to assess the effects of venous sinus stenting on ICP in a small group of patients with IIH. METHODS Ten patients for whom medical therapy had failed were prospectively followed. Ophthalmological examinations were assessed, and patients with venous sinus stenosis on MR angiography proceeded to catheter angiography, venography with assessment of pressure gradient, and ICP monitoring...
December 23, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28004582/weighted-protein-interaction-network-analysis-of-frontotemporal-dementia
#9
Raffaele Ferrari, Ruth C Lovering, John Hardy, Patrick A Lewis, Claudia Manzoni
The genetic analysis of complex disorders has undoubtedly led to the identification of a wealth of associations between genes and specific traits. However, moving from genetics to biochemistry one gene at a time has, to date, rather proved inefficient and under-powered to comprehensively explain the molecular basis of phenotypes. Here we present a novel approach - weighted protein-protein interaction network analysis (W-PPI-NA) - to highlight key functional players within relevant biological processes associated with a given trait...
December 22, 2016: Journal of Proteome Research
https://www.readbyqxmd.com/read/27998460/-treatment-of-idiopathic-intracranial-hypertension
#10
Y H Wang, J Ma, Y Zhong
Idiopathic intracranial hypertension(IIH) is a kind of diffuse brain swelling disease. Several causes could lead to IIH. Intracranial venous circulatory disturbance is more common. The clinical manifestations include intracranial pressure increased, headache and papilledema. Since IIH usually has serious impact on vision even blindness, the diagnosis and corresponding treatment are especially important. This review is to discuss the new insights on the therapeutic options of IIH, which cover medical treatment, weight-losing therapy, surgical treatment, interventional therapy and supportive treatment...
December 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27981458/bariatric-surgery-or-non-surgical-weight-loss-for-idiopathic-intracranial-hypertension-a-systematic-review-and-comparison-of-meta-analyses
#11
REVIEW
James H Manfield, Kenny K-H Yu, Evangelos Efthimiou, Ara Darzi, Thanos Athanasiou, Hutan Ashrafian
BACKGROUND: Idiopathic intracranial hypertension (IIH) is associated with obesity and weight loss by any means is considered beneficial in this condition. OBJECTIVES: This study aims to appraise bariatric surgery vs. non-surgical weight-loss (medical, behavioural and lifestyle) interventions in IIH management. METHODS: A systematic review and meta-analyses of surgical and non-surgical studies. RESULTS: Bariatric surgery achieved 100% papilloedema resolution and a reduction in headache symptoms in 90...
February 2017: Obesity Surgery
https://www.readbyqxmd.com/read/27935482/dural-sinus-stenting-for-idiopathic-intracranial-hypertension-factors-associated-with-hemodynamic-failure-and-management-with-extended-stenting
#12
David A Kumpe, Joshua Seinfeld, Xianchen Huang, Quelin Mei, David E Case, Christopher D Roark, Prem S Subramanian, Kimberly E Lind, Victoria S Pelak, Jeffrey L Bennett
BACKGROUND: Some patients undergoing dural sinus stenting for idiopathic intracranial hypertension (IIH) develop clinical and hemodynamic failure (recurrence of the pressure gradient) owing to stent-adjacent stenosis. OBJECTIVE: To characterize factors associated with hemodynamic failure, and to describe outcomes of patients after repeat stenting. MATERIALS AND METHODS: We reviewed the initial and follow-up clinical, venographic, and hemodynamic data in 39 patients with IIH treated over 17 years with stenting...
November 8, 2016: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/27932598/how-much-cerebrospinal-fluid-should-we-remove-prior-to-measuring-a-closing-pressure
#13
Son H McLaren, Michael C Monuteaux, Atima C Delaney, Assaf Landschaft, Amir A Kimia
OBJECTIVE: The objective of this study was to identify a relationship between cerebrospinal fluid (CSF) volume removal and change in CSF pressure in children with suspected idiopathic intracranial hypertension (IIH). METHODS: We performed a cross-sectional study of children 22 years and younger who underwent a lumbar puncture (LP) and had a documented opening pressure, closing pressure, and volume removed. Relationship between volume removal and pressure change was determined using a fractional polynomial regression procedure...
December 8, 2016: Journal of Child Neurology
https://www.readbyqxmd.com/read/27930576/hyperthyroidism-secondary-to-hysterosalpingography-an-extremely-rare-complication-a-case-report
#14
Guotao Ma, Rui Mao, Haixin Zhai
RATIONALE: Hysterosalpingography (HSG), a standard procedure for the evaluation of women with infertility and repetitive pregnancy loss, is associated with complications such as uterine perforation, infection, allergic reactions, syncope, hemorrhage and shock, and pulmonary or retinal embolus. However, hyperthyroidism has not been reported as one of its complications. PATIENT CONCERNS AND DIAGNOSES: We report the case of a 33-year-old euthyroid woman who presented to our hospital with palpitation, hand tremor, fatigue, and excessive sweating after HSG...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27929555/-idiopathic-intracranial-hypertension-as-a-cause-of-headache
#15
Anette Huuse Farmen, Geir Ringstad, Emilia Kerty
Idiopathic intracranial hypertension (IIH) is characterised by increased intracranial pressure with normal cerebrospinal fluid, and no evidence of space occupying process, meningeal pathology or venous thrombosis. The condition is associated with obesity, especially in women of childbearing age. IIH is a rare but serious cause of headache, and constitutes a differential diagnosis for sudden-onset headache, particularly if the patient has visual disturbances not related to migraine and reports pulsatile tinnitus, cranial nerve palsy or radiculopathy...
December 2016: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
https://www.readbyqxmd.com/read/27928418/a-possible-role-for-temporary-lumbar-drainage-in-the-management-of-idiopathic-intracranial-hypertension
#16
Peter Gates, Peter McNeill
This paper reports 14 patients with idiopathic intracranial hypertension (IIH) who experienced immediate and sustained resolution of their IIH; 13 in the setting of a low-pressure headache and 1 who underwent lumbar drainage for 4 days draining the cerebrospinal fluid (CSF) at a rate of 5-15 mL/h. These observations, if confirmed, suggest that draining CSF using a temporary lumbar drain draining CSF at a rate greater than it is produced may potentially have a pivotal role in the management of IIH.
December 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27928402/neuroimaging-features-of-idiopathic-intracranial-hypertension-persist-after-resolution-of-papilloedema
#17
Randy O Chang, Brigid K Marshall, Noushin Yahyavi, Aseem Sharma, Julia Huecker, Mae O Gordon, Collin McClelland, Gregory P Van Stavern
Papilloedema is a key clinical finding in the diagnosis of idiopathic intracranial hypertension (IIH). However, newly proposed criteria allow diagnosis without papilloedema only if certain neuroimaging features are present. It is currently unclear if these findings persist upon resolution of papilloedema and IIH. A retrospective chart review identified three groups of patients (six per group) who had received orbital imaging within 4 weeks of fundoscopic examination: (1) IIH patients without active papilloedema, (2) IIH patients with active papilloedema, and (3) patients with no history of IIH or papilloedema...
August 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27928378/sixth-nerve-palsy-in-paediatric-intracranial-hypertension
#18
Julia E Reid, Rachel E Reem, Shawn C Aylward, David L Rogers
The purpose of this study was to report the incidence and describe the characteristics of sixth cranial nerve (CN VI) palsy in paediatric patients with intracranial hypertension (IH). A retrospective chart review of central Ohio children diagnosed with IH over the 3-year period from 2010 to 2013 was conducted. IH without identifiable cause was defined as idiopathic intracranial hypertension (IIH), whereas IH with identifiable pathologic aetiology was deemed secondary intracranial hypertension (SIH). A subset of patients with CN VI palsy was identified...
February 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27903844/therapeutic-approaches-to-pediatric-pseudotumor-cerebri-new-insights-from-literature-data
#19
Giovanna Vitaliti, Piero Pavone, Nassim Matin, Omidreza Tabatabaie, Salvatore Cocuzza, Michele Vecchio, Luigi Maiolino, Paola Di Mauro, Angelo Conti, Riccardo Lubrano, Agostino Serra, Raffaele Falsaperla
The pseudotumor cerebri syndrome (PTCS), also known as idiopathic intracranial hypertension (IIH), is characterized by signs and symptoms of increased intracranial pressure such as headache and cranial nerve palsies, in the absence of any space-occupying mass. This condition commonly affects overweight women of childbearing age, even if it is also frequent in men and children. Children with PTCS may present with atypical signs and symptoms, with a different prognosis compared to adults. However, the treatment is the same for both children and adults, even if there are no strict treatment guidelines in regards...
November 30, 2016: International Journal of Immunopathology and Pharmacology
https://www.readbyqxmd.com/read/27899037/a-comparison-of-hmgb1-concentrations-between-cerebrospinal-fluid-and-blood-in-patients-with-neurological-disease
#20
Lauren Elizabeth Walker, Michael John Griffiths, Fiona McGill, Penelope Lewthwaite, Graeme John Sills, Andrea Jorgensen, Daniel James Antoine, Tom Solomon, Anthony Guy Marson, Munir Pirmohamed
AIMS: To determine whether a correlation exists between paired cerebrospinal fluid (CSF) and serum levels of a novel inflammatory biomarker, high-mobility group box 1 (HMGB1), in different neurological conditions. METHODS: HMGB1 was measured in the serum and CSF of 46 neurological patients (18 idiopathic intracranial hypertension [IIH], 18 neurological infection/inflammation [NII] and 10 Rasmussen's encephalitis [RE]). RESULTS: Mean serum (± SD) HMGB1 levels were 1...
December 8, 2016: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
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