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https://www.readbyqxmd.com/read/28336305/from-point-process-observations-to-collective-neural-dynamics-nonlinear-hawkes-process-glms-low-dimensional-dynamics-and-coarse-graining
#1
Wilson Truccolo
This review presents a perspective on capturing collective dynamics in recorded neuronal ensembles based on multivariate point process models, inference of low-dimensional dynamics and coarse graining of spatiotemporal measurements. A general probabilistic framework for continuous time point processes is reviewed, with an emphasis on multivariate nonlinear Hawkes processes with exogenous inputs. A point process generalized linear model (PP-GLM) framework for the estimation of discrete time multivariate nonlinear Hawkes processes is described...
March 20, 2017: Journal of Physiology, Paris
https://www.readbyqxmd.com/read/28335689/trends-of-occupational-hygiene-in-finland
#2
Rauno Pääkkönen, Milja Koponen
The aim of this work is to evaluate and describe the current status of, and prospects for, the future of occupational hygiene in Finland. The main sources of information include a seminar held in the annual meeting of Finnish Occupational Hygiene Society, and interviews with different stakeholders. Nanotechnology and other new materials, changing work environments, circular economy including green jobs, new medical methods, and advances of construction methods were recognised as future challenges. Future work opportunities for occupational hygiene experts included exposure assessments in indoor air surveys, private consulting and entrepreneurship in general, international activities, and product safety issues...
March 24, 2017: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/28334143/boosting-and-decreasing-action-prediction-abilities-through-excitatory-and-inhibitory-tdcs-of-inferior-frontal-cortex
#3
Alessio Avenanti, Riccardo Paracampo, Laura Annella, Emmanuele Tidoni, Salvatore Maria Aglioti
Influential theories suggest that humans predict others' upcoming actions by using their own motor system as an internal forward model. However, evidence that the motor system is causally essential for predicting others' actions is meager. Using transcranial direct current stimulation (tDCS), we tested the role of the inferior frontal cortex (IFC), in action prediction (AP). We devised a novel AP task where participants observed the initial phases of right-hand reaching-to-grasp actions and had to predict their outcome (i...
March 14, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28334082/decoding-grasping-movements-from-the-parieto-frontal-reaching-circuit-in-the-nonhuman-primate
#4
Koen Nelissen, Prosper Agbesi Fiave, Wim Vanduffel
Prehension movements typically include a reaching phase, guiding the hand toward the object, and a grip phase, shaping the hand around it. The dominant view posits that these components rely upon largely independent parieto-frontal circuits: a dorso-medial circuit involved in reaching and a dorso-lateral circuit involved in grasping. However, mounting evidence suggests a more complex arrangement, with dorso-medial areas contributing to both reaching and grasping. To investigate the role of the dorso-medial reaching circuit in grasping, we trained monkeys to reach-and-grasp different objects in the dark and determined if hand configurations could be decoded from functional magnetic resonance imaging (MRI) responses obtained from the reaching and grasping circuits...
February 18, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28332411/underneath-the-academic-curiosity
#5
Miguel Leal-Rato
As a medical student, I have now almost 6 years of academic studies and clinical interaction with numerous patients, though sometimes brief and superficial. I have found that sometimes it is truly hard to grasp how humane a person is behind their sickness. Fortunately, I have been hitherto able to avoid the almost natural desensitization our degree imposes upon us, either through my own process of thought or through a kind warning of some of "my" patients. Having been particularly thrown aback by the keen eye of a patient I had the opportunity to meet in an Oncology ward, I realized that I had much more to consider when studying a clinical case and that rarely a cancer (or a disease whatever it may be) is but a cancer...
March 23, 2017: Medical Teacher
https://www.readbyqxmd.com/read/28332310/arboreal-locomotion-in-eurasian-harvest-mice-micromys-minutus-rodentia-muridae-the-gaits-of-small-mammals
#6
Nikolaos-Evangelos Karantanis, Leszek Rychlik, Anthony Herrel, Dionisios Youlatos
Body size imposes significant constraints on arboreal locomotion. Despite the wealth of research in larger arboreal mammals, there is a lack of data on arboreal gaits of small mammals. In this context, the present study explores arboreal locomotion in one of the smallest rodents, the Eurasian harvest mice Micromys minutus (∼10 g). We examined gait metrics (i.e., diagonality, duty factor [DF], DF index, velocity, stride length, and stride frequency) of six adult male mice on simulated arboreal substrates of different sizes (2, 5, 10, and 25 mm) and inclinations (0(0) and 45(0) )...
March 23, 2017: Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
https://www.readbyqxmd.com/read/28331145/modified-marionette-technique-for-laparoscopic-colorectal-surgery
#7
Seiichi Shinji, Hayato Kan, Takeshi Yamada, Michihiro Koizumi, Aya Yamagishi, Yasuyuki Yokoyama, Goro Takahashi, Takuma Iwai, Keisuke Hara, Kohki Takeda, Keiichiro Ohta, Eiji Uchida
INTRODUCTION: Single-port laparoscopic surgery has some technical limitations with respect to control of the forceps inserted through the single-access site, which results in increased internal collisions due to coaxial alignment of the instruments, as well as and decreased range of motion and visualization. To overcome these limitations, we employ a "modified marionette technique" as a way to carry out laparoscopic colorectal surgery. Materials and Surgical Technique: The procedures for the modified marionette technique are performed as follows: An Internal Organ Retractor (IOR)™ and an atraumatic clip designed to firmly grasp tissue, with 1-0 nylon thread, are inserted through a 12-mm trocar and secured in place where adequate visualization and traction for cutting with a radio knife is required...
2017: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/28331008/coordination-of-the-pincer-grasp-and-transport-following-a-mechanical-perturbation-of-the-index-finger
#8
Luis F Schettino, Sergei V Adamovich, Eugene Tunik
Our understanding of reach-to-grasp movements has evolved from the original formulation of the movement as two semi-independent visuomotor channels to one of interdependence. In spite of a number of important contributions involving perturbations of the reach or the grasp, some of the features of the movement, such as the presence or absence of coordination between the digits during the pincer grasp and the extent of spatio-temporal interdependence between the transport and the grasp are still unclear. In this study, we physically perturbed the index finger into extension during grasping closure, on a minority of trials, to test whether modifying the movement of one digit would affect the movement of the opposite digit, suggestive of an overarching coordinative process...
March 22, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28327348/know-thy-agency-in-predictive-coding-meta-monitoring-over-forward-modeling
#9
Tomohisa Asai
Though the computation of agency is thought to be based on prediction error, it is important for us to grasp our own reliability of that detected error. Here, the current study shows that we have a meta-monitoring ability over our own forward model, where the accuracy of motor prediction and therefore of the felt agency are implicitly evaluated. Healthy participants (N=105) conducted a simple motor control task and SELF or OTHER visual feedback was given. The relationship between the accuracy and confidence in a mismatch detection task and in a self-other attribution task was examined...
March 16, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28324934/hand-rehabilitation-after-stroke-using-a-wearable-high-dof-spring-powered-exoskeleton
#10
Tianyao Chen, Peter S Lum
Stroke patients often have inappropriate finger flexor activation and finger extensor weakness, which makes it difficult to open their affected hand for functional grasp. The goal was to develop a passive, lightweight, wearable device to enable improved hand function during performance of activities of daily living. The device, HandSOME II, assists with opening the patient's hand using 11 elastic actuators that apply extension torques to finger and thumb joints. Device design and initial testing are described...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324136/the-inimitable-mouth-task-dependent-kinematic-differences-are-independent-of-terminal-precision
#11
Jason W Flindall, Claudia L R Gonzalez
Previous studies in our lab have described kinematic difference between grasp-to-eat and grasp-to-place movements, whereby participants produce smaller maximum grip apertures (MGAs) when grasping to bring the item to the mouth than when grasping to bring the item to a container near the mouth. This task difference is limited to right-handed movements, regardless of handedness; it has, therefore, been interpreted as evidence of left-hemisphere lateralization of the grasp-to-eat and other hand-to-mouth grasping movements...
March 21, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28323685/ipsilateral-tremor-like-grasp-reaction-in-a-patient-with-ischemic-stroke
#12
Yuichiro Inatomi, Makoto Nakajima, Toshiro Yonehara, Yukio Ando
Reports of involuntary ipsilateral movements after a stroke are rare, and none have described a patient with both an instinctive grasp reaction and tremor-like movement ipsilateral to the acute stroke lesion. We here report such a patient. A 76-year-old right-handed woman with a past history of left thalamic hemorrhage developed left hemiparesis, an instinctive grasp reaction, and a peculiar involuntary movement of her right arm. This involuntary movement was stereotyped and sometimes rhythmical, with a groping or picking-like action...
March 2017: Cognitive and Behavioral Neurology: Official Journal of the Society for Behavioral and Cognitive Neurology
https://www.readbyqxmd.com/read/28322629/promoting-the-wellbeing-of-lesbian-gay-bisexual-and-transgender-forced-migrants-in-canada-providers-perspectives
#13
Sarilee Kahn, Edward Alessi, Leah Woolner, Hanna Kim, Christina Olivieri
Researchers are beginning to document the experiences of lesbian, gay, bisexual and transgender (LGBT) forced migrants in settlement. However, studies exploring the perceptions of service providers working with this vulnerable population are limited. These may shed light on the challenges of meeting the needs of LGBT forced migrants, especially mental health issues and problems. This qualitative study elicited the views of 22 Canadian service providers, including advocates, lawyers and mental health practitioners, who serve LGBT forced migrants...
March 21, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28321887/simplification-of-visual-rendering-in-simulated-prosthetic-vision-facilitates-navigation
#14
Victor Vergnieux, Marc J-M Macé, Christophe Jouffrais
Visual neuroprostheses are still limited and simulated prosthetic vision (SPV) is used to evaluate potential and forthcoming functionality of these implants. SPV has been used to evaluate the minimum requirement on visual neuroprosthetic characteristics to restore various functions such as reading, objects and face recognition, object grasping, etc. Some of these studies focused on obstacle avoidance but only a few investigated orientation or navigation abilities with prosthetic vision. The resolution of current arrays of electrodes is not sufficient to allow navigation tasks without additional processing of the visual input...
March 21, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28321287/keeping-safe-intra-individual-consistency-in-obstacle-avoidance-behaviour-across-grasping-and-locomotion-tasks
#15
Karina Kangur, Jutta Billino, Constanze Hesse
Successful obstacle avoidance requires a close coordination of the visual and the motor systems. Visual information is essential for adjusting movements in order to avoid unwanted collisions. Yet, established obstacle avoidance paradigms have typically either focused on gaze strategies or on motor adjustments. Here we were interested in whether humans show similar visuomotor sensitivity to obstacles when gaze and motor behaviour are measured across different obstacle avoidance tasks. To this end, we measured participants' hand movement paths when grasping targets in the presence of obstacles as well as their gaze behaviour when walking through a cluttered hallway...
January 2017: I-Perception
https://www.readbyqxmd.com/read/28320845/decoding-information-for-grasping-from-the-macaque-dorsomedial-visual-stream
#16
Matteo Filippini, Rossella Breveglieri, M Ali Akhras, Annalisa Bosco, Eris Chinellato, Patrizia Fattori
Neuro-decoders have been developed by researchers mostly to control neuro-prosthetic devices, but also to shed new light on neural functions. In this study, we show that signals representing grip configurations can be reliably decoded from neural data acquired from area V6A of the monkey medial posterior parietal cortex (PPC). Two Macaca fascicularis were trained to perform an instructed-delay reach-to-grasp task in the dark and in the light towards objects of different shapes. Population neural activity was extracted at various time intervals; on vision of the objects, the delay before movement, and grasp execution...
March 20, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28317044/an-intuitive-method-of-duct-to-mucosa-pancreaticojejunostomy-after-pancreaticoduodenectomy-use-of-one-step-circumferential-interrupted-sutures
#17
Moonwhan Kim, Woo Young Shin, Keon-Young Lee, Seung-Ik Ahn
Pancreaticoenteric anastomosis is the origin of postoperative pancreatic fistula (POPF). Although a variety of methods have been proposed to decrease the POPF rate, randomized controlled trials performed so far have failed to demonstrate superiority of any particular method to the others. Cattell-Warren duct-to-mucosa pancreaticojejunostomy (PJ) is a widely practiced procedure. Their method is challenging, especially when the pancreatic duct is small. We assumed that the difficulty resides in the pancreatic duct becoming difficult to access when the posterior row is tied before suturing the anterior row...
February 2017: Ann Hepatobiliary Pancreat Surg
https://www.readbyqxmd.com/read/28315945/organization-of-the-reach-and-grasp-in-head-fixed-vs-freely-moving-mice-provides-support-for-multiple-motor-channel-theory-of-neocortical-organization
#18
Ian Q Whishaw, Jamshid Faraji, Jessica Kuntz, Behroo Mirza Agha, Mukt Patel, Gerlinde A S Metz, Majid H Mohajerani
Multiple motor channel (MMC) theory of neocortical organization proposes that complex movements, such as reaching for a food item to eat, are produced by the coordinated action of separate neural channels. For example, the human reach-to-grasp act is mediated by two visuo-parieto-motor cortex channels, one for the reach and one for the grasp. The present analysis asked whether there is a similar organization of reach-and-grasp movements in the mouse. The reach-to-eat movements of the same mice were examined from high-shutter speed, frame-by-frame video analysis in three tasks in which the mice obtained equivalent success scores: when freely-moving reaching for food pellets, when head-fixed reaching for food pellets, and when head-fixed reaching for pieces of pasta...
March 18, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28314812/improvement-in-arm-and-hand-function-after-a-stroke-with-task-oriented-training
#19
Sharon Israely, Gerry Leisman, Eli Carmeli
A man aged 77 years sustained a left-hemisphere stroke with right hemiparesis. After spending 10 days in the hospital, he was referred to an area rehabilitation centre. There he carried out daily physical, occupational and speech therapy, with an emphasis on task-oriented treatment. The patient's upper-extremity motor performance was evaluated at admission to the rehabilitation centre and before leaving the hospital by 3 different measurement tools: the upper-extremity motor part of the Fugl-Meyer assessment scale, electromyography in hand-reach and grasp and object manipulation and handwriting tasks...
March 17, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28314630/experiences-of-being-parents-of-young-adults-living-with-recessive-limb-girdle-muscular-dystrophy-from-a-salutogenic-perspective
#20
Anna Carin Aho, Sally Hultsjö, Katarina Hjelm
Recessive limb-girdle muscular dystrophies (LGMD2) involve progressive muscle weakness. Parental support is important for young adults living with LGMD2, but no study has been identified focusing on the parents' experiences. The salutogenic perspective concentrates on how daily life is comprehended, managed and found meaningful, i.e. the person's sense of coherence. The aim of this study was to describe, from a salutogenic perspective, experiences of being parents of young adults living with LGMD2. Nineteen participants were included...
February 3, 2017: Neuromuscular Disorders: NMD
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