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Empyema in children

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https://www.readbyqxmd.com/read/28474099/a-three-step-diagnosis-of-pediatric-pneumonia-at-the-emergency-department-using-clinical-predictors-c-reactive-protein-and-pneumococcal-pcr
#1
Gabriel Alcoba, Kristina Keitel, Veronica Maspoli, Laurence Lacroix, Sergio Manzano, Mario Gehri, René Tabin, Alain Gervaix, Annick Galetto-Lacour
Recommendations for the management of community-acquired pneumonia (CAP) advocate that, in the absence of the clinical and laboratory findings typical of bacterial CAP, antibiotics are not required. However, the true value of the clinical and laboratory predictors of pediatric CAP still needs to be assessed. This prospective cohort study in three emergency departments enrolled 142 children with radiological pneumonia. Pneumonia with lung consolidation was the primary endpoint; complicated pneumonia (bacteremia, empyema, or pleural effusion) was the secondary endpoint...
May 4, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28468869/what-is-the-best-treatment-option-for-empyema-requiring-drainage-in-children
#2
Christopher William Course, Ruth Hanks, Iolo Doull
No abstract text is available yet for this article.
May 3, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28450195/evaluation-of-the-eazyplex-mrsa-assay-for-the-rapid-detection-of-staphylococcus-aureus-in-pleural-and-synovial-fluid
#3
D Henares, P Brotons, X Buyse, I Latorre, H D de Paz, C Muñoz-Almagro
OBJECTIVE: Loop-mediated isothermal amplification (LAMP) is a simple and sensitive technique for rapid microbiological diagnosis. The aim of this study was to evaluate the analytical and diagnostic performance of the LAMP eazyplex MRSA test for the direct detection and differentiation of methicillin-susceptible (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) in synovial/pleural fluid. METHODS: Analytical validation included the determination of the limit of detection (LoD) and analytical specificity of the eazyplex MRSA test...
April 24, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28339727/rapid-decrease-in-rates-of-hospitalization-resulting-from-invasive-pneumococcal-disease-and-community-acquired-pneumonia-in-children-aged-60-months-after-13-valent-pneumococcal-conjugate-vaccine-introduction-in-argentina
#4
Eduardo L López, Eduardo Glatstein, Gustavo C Ezcurra, Marisa Iacono, Eduardo Teplitz, Analía V Garnero, Daniela L Lazzarini, Miryan Vázquez, María M Contrini
Background.: In January 2012, Argentina included universal pneumococcal vaccination in the routine childhood vaccination program using a 13-valent pneumococcal conjugate vaccine (PCV13). A 2 + 1 schedule (2 doses in the first year of life and a booster dose at 12 months of age) in children aged <2 years and 2-dose catch-up immunization in children aged 13 to 24 months was administered during the first year of vaccine introduction. The purpose of this study was to assess the burdens of invasive pneumococcal disease (IPD) and/or community-acquired pneumonia (CAP) in hospitalized children younger than 5 years during the first 2 years of the program compared to those in the prevaccination period in our setting...
February 23, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28304084/surgical-versus-non-surgical-management-for-pleural-empyema
#5
REVIEW
Mark D Redden, Tze Yang Chin, Mieke L van Driel
BACKGROUND: Empyema refers to pus in the pleural space, commonly due to adjacent pneumonia, chest wall injury, or a complication of thoracic surgery. A range of therapeutic options are available for its management, ranging from percutaneous aspiration and intercostal drainage to video-assisted thoracoscopic surgery (VATS) or thoracotomy drainage. Intrapleural fibrinolytics may also be administered following intercostal drain insertion to facilitate pleural drainage. There is currently a lack of consensus regarding optimal treatment...
March 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28289673/chronic-suppurative-lung-disease-in-children-definition-and-spectrum-of-disease
#6
REVIEW
Gregory J Redding, Edward R Carter
The most common clinical suppurative lung conditions in children are empyema, lung abscess, and bronchiectasis, and to a less often necrotizing pneumonia. Until recently, bronchiectasis was the most common form of persistent suppurative lung disease in children. Protracted bacterial bronchitis is a newly described chronic suppurative condition in children, which is less persistent but more common than bronchiectasis (1). In addition, the term "chronic suppurative lung disease" has been used recently to describe the clinical features of bronchiectasis when the radiographic features needed to make a diagnosis of bronchiectasis are absent...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28273226/parapneumonic-pleural-effusion-reality-and-strategies-in-an-amazon-university-hospital
#7
Claudia Giselle Santos Arêas, Geraldo Roger Normando Júnior, Orlando Sandoval Farias Júnior, Irna Carla DO Rosário Souza Carneiro
OBJECTIVE: to define the profile and analyze the postoperative evolution of children with parapneumonic pleural effusion (PPE), and to evaluate strategies used in the presence of diagnostic and therapeutic limitations, emphasizing the open thoracic drainage (OTD) . METHODS: we conducted a cross-sectional, prospective, analytical study in which we followed children admitted in an Amazon university hospital with surgically addressed PPE, from October 2010 to October 2011...
December 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28249015/impact-of-ten-valent-pneumococcal-conjugate-vaccine-on-pneumonia-in-finnish-children-in-a-nation-wide-population-based-study
#8
Arto A Palmu, Hanna Rinta-Kokko, Hanna Nohynek, J Pekka Nuorti, Terhi M Kilpi, Jukka Jokinen
BACKGROUND: The ten-valent pneumococcal conjugate vaccine (PCV10) was introduced into the Finnish National Vaccination Program (NVP) in September 2010 using a 2+1 schedule (3, 5, 12 months). We estimated the direct and indirect effects of PCV10 on pneumonia among children to evaluate the public health impact of the vaccine. METHODS: We conducted a nation-wide population-based, observational study comparing rates of pneumonia in children before and after the NVP introduction...
2017: PloS One
https://www.readbyqxmd.com/read/27989426/surgical-management-of-complicated-necrotizing-pneumonia-in-children
#9
Jin-Yao Lai, Wendy Yang, Yung-Ching Ming
BACKGROUND: There are no well-established indications for the surgical management of acute necrotizing pneumonitis in children. This study presents our experience regarding this challenging topic. METHODS: Between 2002 and 2009, 56 necrotizing pneumonitis patients with empyema were treated surgically. The outcomes were analyzed retrospectively. Computed tomography findings of massive lung necrosis or large cavities involving more than 50% of the involved lobe were deemed to be complicated necrotizing pneumonitis...
October 28, 2016: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/27832918/changes-in-empyema-among-u-s-children-in-the-pneumococcal-conjugate-vaccine-era
#10
Andrew D Wiese, Marie R Griffin, Yuwei Zhu, Edward F Mitchel, Carlos G Grijalva
BACKGROUND: Parapneumonic empyema, a serious complication of pneumonia, started increasing among U.S. children before the introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) in 2000, and continued afterwards. This increase was due in part to pneumococcal serotypes not included in PCV7 that were included in the new 13-valent (PCV13) vaccine introduced in 2010. We assessed changes in the incidence of empyema hospitalizations among U.S. children after PCV13 introduction. METHODS: We calculated annualized empyema hospitalization rates among U...
December 7, 2016: Vaccine
https://www.readbyqxmd.com/read/27743745/use-of-transcranial-doppler-for-management-of-central-nervous-system-infections-in-critically-ill-children
#11
Laurence Ducharme-Crevier, Michele G Mills, Priya M Mehta, Craig M Smith, Mark S Wainwright
BACKGROUND: The primary objective of this study was to characterize changes in cerebral blood flow measured using transcranial Doppler in children with central nervous system infections. We hypothesized that children with central nervous system infections have abnormal cerebral blood flow, associated with a greater frequency of complications and poor neurological outcome. METHODS: We conducted a single-center, retrospective study of children admitted to the neonatal or pediatric intensive care unit with central nervous system infection and undergoing transcranial Doppler as part of routine care between March 2011 and July 2015...
December 2016: Pediatric Neurology
https://www.readbyqxmd.com/read/27648553/therapy-of-645-children-with-parapneumonic-effusion-and-empyema-a-german-nationwide-surveillance-study
#12
Florian J Segerer, Karin Seeger, Anna Maier, Christine Hagemann, Christoph Schoen, Mark van der Linden, Andrea Streng, Markus A Rose, Johannes G Liese
OBJECTIVE: To evaluate the initial management of pediatric parapneumonic effusion or pleural empyema (PPE/PE) with regard to length of hospital stay (LOS). METHODS: Collection of pediatric PPE/PE cases using a nationwide surveillance system (ESPED) from 10/2010 to 06/2013, in all German pediatric hospitals. Inclusion of PPE/PE patients <18 years of age requiring drainage or with a PPE/PE persistence >7 days. Staging of PPE/PE based on reported pleural sonographic imaging...
April 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27582630/impact-of-pneumococcal-conjugate-vaccination-a-retrospective-study-of-hospitalization-for-pneumonia-in-north-east-italy
#13
REVIEW
V Baldo, S Cocchio, T Gallo, P Furlan, E Clagnan, S Del Zotto, M Saia, C Bertoncello, A Buja, T Baldovin
INTRODUCTION: Pneumonia remains a common reason for hospitalizing infants and the elderly worldwide, and streptococcal infection is often responsible. The aim of this study was to assess the burden of pneumonia in a large general population. METHODS: All pneumonia-related hospitalizations from 2004 to 2013 in north-east Italy were identified from the hospital records with a first-listed diagnosis on discharge of bacterial pneumonia, or a first-listed diagnosis on discharge of meningitis, septicemia or empyema associated with a secondary diagnosis of bacterial pneumonia...
2016: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/27511212/risk-factors-for-morbidities-and-mortality-in-children-following-pneumonectomy
#14
Verónica Giubergia, Florencia Alessandrini, Carolina Barrias, Carlos Giuseppucci, Aixa Reusmann, Marcelo Barrenechea, Claudio Castaños
BACKGROUND AND OBJECTIVE: Pneumonectomy (PNE) is a procedure infrequently performed in children. A high morbidity/mortality rate associated with PNE has been described. Few series have been published in the last 15 years. Risk factors associated with morbidity/mortality after PNE were evaluated. Indications, course, survival and complications of PNE in children were also analized. METHODS: In a case series of 51 children who underwent PNE, death within 30 days of surgery, pneumonia, empyema, sepsis, adult respiratory distress syndrome, bronchopleural fistula, bleeding, pneumothorax and post-PNE syndrome were considered major morbidities...
January 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27434828/complications-of-pneumococcal-bacteremia-after-thirteen-valent-conjugate-vaccine-withdrawal
#15
Alfredo Tagarro, Patricia Bote, Aida Sánchez, Enrique Otheo, Juan-Carlos Sanz, David Sanz-Rosa
BACKGROUND: In the Region of Madrid, universal immunization with the 13-serotypes pneumococcal conjugate vaccine (PCV13) started in May 2010. In July 2012, public funding ceased. Vaccination coverage decreased from >95% to 82% in 2013 and to 67% in 2014. Our aim was to investigate the impact of PCV13 withdrawal from Madrid Region universal immunization program on the incidence of complicated pneumococcal bacteremia. METHODS: We performed a multicenter retrospective cohort study, from 2009 to 2014...
December 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27401931/risk-factors-for-local-complications-in-children-with-community-acquired-pneumonia
#16
Katarzyna Krenke, Marta Krawiec, Grażyna Kraj, Joanna Peradzynska, Agnieszka Krauze, Marek Kulus
AIM: The aim of this study was to evaluate the factors that could predict the development of local complications (parapneumonic effusion/pleural empyema, necrotizing pneumonia, and lung abscess) in children with community-acquired pneumonia (CAP). METHODS: Demographic, clinical, and laboratory data were prospectively collected and compared in children with noncomplicated and complicated CAP. RESULTS: Two-hundred and three patients aged from 2 months to 17 years were enrolled...
July 12, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27392317/complicated-community-acquired-pneumonia-in-childhood-different-types-clinical-course-and-outcome
#17
Ira Erlichman, Oded Breuer, David Shoseyov, Malena Cohen-Cymberknoh, Benjamin Koplewitz, Diana Averbuch, Matti Erlichman, Elie Picard, Eitan Kerem
The incidence of pediatric community acquired complicated pneumonia (PCACP) is increasing. Questions addressed: Are different types of PCACP one disease? How do different treatment protocols affect the outcome? METHODS: Retrospective analysis of medical records of PCACP hospitalizations in the three major hospitals in Jerusalem in the years 2001-2010 for demographics, clinical presentation, management, and outcome. RESULTS: Of the 144 children (51% aged 1-4 years), 91% of Jewish origin; 40% had para-pneumonic effusion (PPE), 40% empyema (EMP), and 20% necrotizing pneumonia (NP)...
February 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27339249/nonsteroidal-anti-inflammatory-drug-without-antibiotics-for-acute-viral-infection-increases-the-empyema-risk-in-children-a-matched-case-control-study
#18
Muriel Le Bourgeois, Agnès Ferroni, Marianne Leruez-Ville, Emmanuelle Varon, Caroline Thumerelle, François Brémont, Michael J Fayon, Christophe Delacourt, Caroline Ligier, Laurence Watier, Didier Guillemot
OBJECTIVE: To investigate the risk factors of empyema after acute viral infection and to clarify the hypothesized association(s) between empyema and some viruses and/or the use of nonsteroidal anti-inflammatory drugs (NSAIDs). STUDY DESIGN: A case-control study was conducted in 15 centers. Cases and controls were enrolled for a source population of children 3-15 years of age with acute viral infections between 2006 and 2009. RESULTS: Among 215 empyemas, 83 cases (children with empyema and acute viral infection within the 15 preceding days) were included, and 83 controls (children with acute viral infection) were matched to cases...
August 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27320108/pneumonia-with-empyema-among-children-in-the-first-five-years-of-high-coverage-with-13-valent-pneumococcal-conjugate-vaccine
#19
George A Syrogiannopoulos, Aspasia N Michoula, Georgios Tsimitselis, Katerina Vassiou, Denise C Chryssanthopoulou, Ioanna N Grivea
BACKGROUND: Parapneumonic effusions in children are usually associated with pneumococcal infections. In Greece, the 7-valent pneumococcal conjugate vaccine was replaced by higher-valent pneumococcal conjugate vaccines (PCVs); 10-valent was introduced in May 2009 and 13-valent (PCV13) in June 2010. Since July 2010, PCV13 has been the most commonly used PCV. In a study conducted at the University General Hospital of Larissa, Central Greece, from January 2012 to January 2016, 85.7% of children born after the implementation of PCV13 and aged 24-59 months had received the complete series (3 + 1 immunization schedule) of PCV13...
October 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27296817/etiology-of-parapneumonic-effusion-and-pleural-empyema-in-children-the-role-of-conventional-and-molecular-microbiological-tests
#20
Katarzyna Krenke, Ewa Sadowy, Edyta Podsiadły, Waleria Hryniewicz, Urszula Demkow, Marek Kulus
BACKGROUND: An increasing incidence of parapneumonic effusion and pleural empyema (PPE/PE) has been reported in recent studies. As only few data on etiology of PPE/PE in Central Europe have been reported, we undertook a study on the etiology of PPE/PE in children, using both standard culture and molecular techniques. METHODS: This prospective study was conducted between June 2011 and December 2013. Consecutive children with PPE/PE complicating community acquired pneumonia, who required diagnostic/therapeutic thoracentesis were included...
July 2016: Respiratory Medicine
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