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parapneumonic effusions in children

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https://www.readbyqxmd.com/read/28673835/when-should-parapneumonic-pleural-effusions-be-drained-in-children
#1
REVIEW
Gilberto Bueno Fischer, Helena Teresinha Mocelin, Cistiano Feijó Andrade, Edgar E Sarria
Pneumonia is an important health problem in children, and parapneumonic pleural effusion (PPE) is a frequent complication. There is no standard strategy for treating PPE, reflected in the few international guidelines that have been published on the issue. Compared to adults, there is no consensus on the utility of pleural fluid analysis in paediatric PPE. This is because of the lack of good evidence either in favour or against it and the risks of procedural sedation for acquiring pleural fluid for analysis to guide management...
June 1, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28626910/intravenous-and-intracavitary-use-of-contrast-enhanced-ultrasound-in-the-evaluation-and-management-of-complicated-pediatric-pneumonia
#2
Annamaria Deganello, Vasileios Rafailidis, Maria E Sellars, Aikaterini Ntoulia, Kleanthi Kalogerakou, Gary Ruiz, David O Cosgrove, Paul S Sidhu
Pediatric pneumonia can be complicated by necrotizing pneumonia or a parapneumonic effusion either in the form of an empyema or a clear effusion. Ultrasonography (US) and computed tomography represent well-established modalities for evaluation of complicated pediatric pneumonia. Contrast-enhanced ultrasound (CEUS) was recently introduced and is gaining increasing acceptance in pediatric imaging. In this case series, we present our initial experience with both intravenous and intracavitary use of CEUS in children with complicated pneumonia...
June 19, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28592263/radiologic-findings-as-a-determinant-and-no-effect-of-macrolide-resistance-on-clinical-course-of-mycoplasma-pneumoniae-pneumonia
#3
In Ae Yoon, Ki Bae Hong, Hoan Jong Lee, Ki Wook Yun, Ji Young Park, Young Hoon Choi, Woo Sun Kim, Hyunju Lee, Byung Wook Eun, Young Min Ahn, Eun Young Cho, Hwa Jin Cho, Eun Hwa Choi
BACKGROUND: With the emergence of macrolide resistance, concerns about the efficacy of macrolides for the treatment of Mycoplasma pneumoniae (MP) pneumonia in children have been raised. This study aimed to determine the effect of macrolide resistance on the outcome of children who were hospitalized with MP pneumonia. METHODS: Between 2010 and 2015, we performed culture of MP from nasopharyngeal samples obtained from children who were hospitalized with pneumonia at five hospitals in Korea...
June 7, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28363363/dexamethasone-for-parapneumonic-pleural-effusion-a-randomized-double-blind-clinical-trial
#4
Alfredo Tagarro, Enrique Otheo, Fernando Baquero-Artigao, María-Luisa Navarro, Rosa Velasco, Marta Ruiz, María Penín, David Moreno, Pablo Rojo, Rosario Madero
OBJECTIVE: To assess whether dexamethasone (DXM) decreases the time to recovery in patients with parapneumonic pleural effusion. STUDY DESIGN: This was a multicenter, randomized, double blind, parallel-group, placebo-controlled clinical trial of 60 children, ranging in age from 1 month to 14 years, with community-acquired pneumonia (CAP) and pleural effusion. Patients received either intravenous DXM (0.25?mg/kg/dose) or placebo every 6 hours over a period of 48 hours, along with antibiotics...
June 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28304084/surgical-versus-non-surgical-management-for-pleural-empyema
#5
REVIEW
Mark D Redden, Tze Yang Chin, Mieke L van Driel
BACKGROUND: Empyema refers to pus in the pleural space, commonly due to adjacent pneumonia, chest wall injury, or a complication of thoracic surgery. A range of therapeutic options are available for its management, ranging from percutaneous aspiration and intercostal drainage to video-assisted thoracoscopic surgery (VATS) or thoracotomy drainage. Intrapleural fibrinolytics may also be administered following intercostal drain insertion to facilitate pleural drainage. There is currently a lack of consensus regarding optimal treatment...
March 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28273226/parapneumonic-pleural-effusion-reality-and-strategies-in-an-amazon-university-hospital
#6
Claudia Giselle Santos Arêas, Geraldo Roger Normando Júnior, Orlando Sandoval Farias Júnior, Irna Carla DO Rosário Souza Carneiro
OBJECTIVE: to define the profile and analyze the postoperative evolution of children with parapneumonic pleural effusion (PPE), and to evaluate strategies used in the presence of diagnostic and therapeutic limitations, emphasizing the open thoracic drainage (OTD) . METHODS: we conducted a cross-sectional, prospective, analytical study in which we followed children admitted in an Amazon university hospital with surgically addressed PPE, from October 2010 to October 2011...
December 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/27850303/664-intrapleural-tpa-therapy-in-children-with-parapneumonic-effusion
#7
Megan Daniel, Josey Hensley, Lisa Steele, Jennifer Muszynski, Melissa Moore-Clingenpeel, Mark Hall
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27709281/stratifying-fibrinolytic-dosing-in-pediatric-parapneumonic-effusion-based-on-ultrasound-grade-correlation
#8
Charles A James, Leah E Braswell, Amir H Pezeshkmehr, Paula K Roberson, James A Parks, Mary B Moore
BACKGROUND: Complicated pleural effusion prolongs the hospital course of pneumonia. Chest tube placement with instillation of fibrinolytic medication allows efficient drain output and decreases hospital stay. OBJECTIVE: To evaluate experience with lower fibrinolytic dose for parapneumonic effusions and to assess potential dose stratification based on a simple ultrasound grading system. MATERIALS AND METHODS: We retrospectively reviewed the medical record to identify children and young adults who received fibrinolytic therapy for parapneumonic effusion and had chest tube placement by an interventional radiology service at a single children's hospital...
January 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/27648553/therapy-of-645-children-with-parapneumonic-effusion-and-empyema-a-german-nationwide-surveillance-study
#9
Florian J Segerer, Karin Seeger, Anna Maier, Christine Hagemann, Christoph Schoen, Mark van der Linden, Andrea Streng, Markus A Rose, Johannes G Liese
OBJECTIVE: To evaluate the initial management of pediatric parapneumonic effusion or pleural empyema (PPE/PE) with regard to length of hospital stay (LOS). METHODS: Collection of pediatric PPE/PE cases using a nationwide surveillance system (ESPED) from 10/2010 to 06/2013, in all German pediatric hospitals. Inclusion of PPE/PE patients <18 years of age requiring drainage or with a PPE/PE persistence >7 days. Staging of PPE/PE based on reported pleural sonographic imaging...
April 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27527890/pleural-effusion-with-negative-culture-a-challenge-for-pneumococcal-diagnosis-in-children
#10
Vinicius Pieta Perez, Juliana Caierão, Gilberto Bueno Fischer, Cícero Armídio Gomes Dias, Pedro Alves d'Azevedo
BACKGROUND: Pneumococcal parapneumonic effusion seems to be increasing in children in the postvaccine era and is frequently associated with negative culture. Due to the low yield of culture, culture-independent tools are evaluated. METHODS: Culture-negative pleural fluid specimens from 38 children with parapneumonic effusion were examined for pneumococcal lytA by quantitative polymerase chain reaction (qPCR) and soluble antigen (C-polysaccharide) using an immunochromatographic test (BinaxNow Streptococcus pneumoniae)...
October 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27401931/risk-factors-for-local-complications-in-children-with-community-acquired-pneumonia
#11
Katarzyna Krenke, Marta Krawiec, Grażyna Kraj, Joanna Peradzynska, Agnieszka Krauze, Marek Kulus
AIM: The aim of this study was to evaluate the factors that could predict the development of local complications (parapneumonic effusion/pleural empyema, necrotizing pneumonia, and lung abscess) in children with community-acquired pneumonia (CAP). METHODS: Demographic, clinical, and laboratory data were prospectively collected and compared in children with noncomplicated and complicated CAP. RESULTS: Two-hundred and three patients aged from 2 months to 17 years were enrolled...
July 12, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27320108/pneumonia-with-empyema-among-children-in-the-first-five-years-of-high-coverage-with-13-valent-pneumococcal-conjugate-vaccine
#12
George A Syrogiannopoulos, Aspasia N Michoula, Georgios Tsimitselis, Katerina Vassiou, Denise C Chryssanthopoulou, Ioanna N Grivea
BACKGROUND: Parapneumonic effusions in children are usually associated with pneumococcal infections. In Greece, the 7-valent pneumococcal conjugate vaccine was replaced by higher-valent pneumococcal conjugate vaccines (PCVs); 10-valent was introduced in May 2009 and 13-valent (PCV13) in June 2010. Since July 2010, PCV13 has been the most commonly used PCV. In a study conducted at the University General Hospital of Larissa, Central Greece, from January 2012 to January 2016, 85.7% of children born after the implementation of PCV13 and aged 24-59 months had received the complete series (3 + 1 immunization schedule) of PCV13...
October 2016: Infectious Diseases
https://www.readbyqxmd.com/read/27296817/etiology-of-parapneumonic-effusion-and-pleural-empyema-in-children-the-role-of-conventional-and-molecular-microbiological-tests
#13
Katarzyna Krenke, Ewa Sadowy, Edyta Podsiadły, Waleria Hryniewicz, Urszula Demkow, Marek Kulus
BACKGROUND: An increasing incidence of parapneumonic effusion and pleural empyema (PPE/PE) has been reported in recent studies. As only few data on etiology of PPE/PE in Central Europe have been reported, we undertook a study on the etiology of PPE/PE in children, using both standard culture and molecular techniques. METHODS: This prospective study was conducted between June 2011 and December 2013. Consecutive children with PPE/PE complicating community acquired pneumonia, who required diagnostic/therapeutic thoracentesis were included...
July 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27103079/metabolomic-profiling-of-infectious-parapneumonic-effusions-reveals-biomarkers-for-guiding-management-of-children-with-streptococcus-pneumoniae-pneumonia
#14
Chih-Yung Chiu, Gigin Lin, Mei-Ling Cheng, Meng-Han Chiang, Ming-Han Tsai, Shen-Hao Lai, Kin-Sun Wong, Sen-Yung Hsieh
Metabolic markers in biofluids represent an attractive tool for guiding clinical management. The aim of this study was to identify metabolic mechanisms during the progress of pleural infection in children with Streptococcus pneumoniae pneumonia. Forty children diagnosed with pneumococcal pneumonia were enrolled and analysis of pleural fluid metabolites categorized by complicated parapneumonic effusions (CPE) and non-CPE was assessed by using (1)H-NMR spectroscopy. Multivariate statistical analysis including principal components analysis (PCA) and partial least-squares discriminant analysis (PLS-DA) were performed...
April 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27059295/incidence-aetiology-and-outcome-of-pleural-empyema-and-parapneumonic-effusion-from-1998-to-2012-in-a-population-of-new-zealand-children
#15
Caroline Mahon, Wendy Walker, Alan Drage, Emma Best
AIM: To document rising incidence rates of childhood empyema and parapneumonic effusion (PPE) in South Auckland, New Zealand between 1998 and 2012; to compare epidemiology, pathogens and outcomes of children with empyema and PPE; and to ascertain whether primary care antibiotic prescribing, delayed presentation, or bacterial epidemiology might account for the rising incident rates. METHODS: Children aged 0 to14 years hospitalised with pleural empyema or PPE were retrospectively identified...
June 2016: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/27032611/trends-in-treatment-of-infectious-parapneumonic-effusions-in-u-s-children-s-hospitals-2004-2014
#16
Robert M Dorman, Kaveh Vali, David H Rothstein
PURPOSE: The purpose of this study was to examine trends in the treatment of patients with infectious parapneumonic effusions in U.S. children's hospitals over the past decade. METHODS: The PHIS database was queried for patients younger than 18years old with pneumonia and pleural effusion in three yearlong periods over the past decade. Variables included age, gender, payer, race/ethnicity, hospital region, hospital type, markers of illness severity, and treatment group (antibiotics alone, chest tube thoracostomy±thrombolytics, video-assisted thoracoscopy (VATS), or thoracotomy)...
June 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/26919911/clinical-characteristics-of-323-children-with-parapneumonic-pleural-effusion-and-pleural-empyema-due-to-community-acquired-pneumonia
#17
Katarzyna Krenke, Emilia Urbankowska, Tomasz Urbankowski, Joanna Lange, Marek Kulus
BACKGROUND: An increasing incidence of parapneumonic effusion and pleural empyema (PPE/PE) in children has been found in several studies published in the last decades. The aim of the study was to evaluate the incidence, etiology, clinical features, treatment strategies and outcomes of PPE/PE in children treated in a referral pulmonary center in central Poland. MATERIAL AND METHODS: We performed a retrospective analysis of clinical, radiological and laboratory data of all children aged between 1 month and 18 years with PPE/PE due to community acquired pneumonia (CAP) between January 2002 and December 2013...
May 2016: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/26787377/bacteremic-pneumonia-before-and-after-withdrawal-of-13-valent-pneumococcal-conjugate-vaccine-from-a-public-vaccination-program-in-spain-a-case-control-study
#18
MULTICENTER STUDY
Alfredo Tagarro, Andrea Benito, Aida Sánchez, Esteban Aznar, Enrique Otheo, David Sanz-Rosa
OBJECTIVE: To compare the incidence and epidemiology of bacteremic community-acquired pneumonia (CAP) in the setting of changes in 13-valent pneumococcal conjugate vaccine (PCV13) coverage. STUDY DESIGN: In the region of Madrid, universal immunization with the PCV13 started in May 2010. In July 2012, public funding ceased. Vaccination coverage decreased from >95% to 82% in 2013 and to 67% in 2014. We performed a multicenter surveillance and case-control study from 2009-2014...
April 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/26527959/surgical-management-of-complicated-parapneumonic-pleural-effusion-in-children
#19
Anca Budusan, Ioan Paraian, Doina Zamora
AIMS: We analyzed and examined the effect of different management strategies on short term outcomes for pediatric patients with parapneumonic pleural effusions. PATIENTS AND METHODS: We retrospectively reviewed 16 cases of children admitted and treated in our department of pediatric surgery for empyema or pleural effusions for a period of 30 months. RESULTS: When chest drains are used alone, patients can make a complete recovery, even with the cost of longer hospital stay...
2013: Clujul Medical (1957)
https://www.readbyqxmd.com/read/26527355/pleural-effusions-in-children-from-southern-brazil
#20
Gilberto Bueno Fischer
Parapneumonic pleural effusions (PPE) are a relatively common (5-40%) complication of paediatric pneumonia. However, in clinical practice the majority of the effusions are small and do not need any further investigation or specific treatment apart from antibiotic therapy. A small number require drainage or surgical intervention. Rarely, significant effusions are associated with non-bacterial pneumonia in the paediatric population. Pleural tuberculosis in our hospital is the second highest cause of pleural effusions related to the high incidence of TB in our city...
January 2016: Paediatric Respiratory Reviews
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