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https://www.readbyqxmd.com/read/28636084/co-morbidities-and-bleeding-in-elderly-patients-with-haemophilia-a-survey-of-the-german-austrian-and-swiss-society-of-thrombosis-and-haemostasis-research-gth
#1
W Miesbach, S-E Reitter-Pfoertner, R Klamroth, F Langer, H-H Wolf, A Tiede, B Siegmund, U Scholz, P R Müller, H Eichler, I Pabinger
BACKGROUND: Nowadays patients with haemophilia survive longer due to improvements in haemophilia care. It has been hypothesized that the bleeding type and frequency may vary with age and are influenced by co-morbidities and co-medication in elderly patients. OBJECTIVES: To investigate a large group of patients older than 60 years of age with haemophilia concerning haemophilia treatment, bleeding pattern changes, co-morbidities, co-medication, bleeding sites and patient mortality...
June 21, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28634521/a-review-of-echocardiograms-in-hypertensive-patients-greater-than-60-years-in-a-community-based-family-medicine-program
#2
Shideh Doroudi, Michael D DeLisi, Vincent A DeBari
Background: Heart disease as a result of Hypertension is known to occur. Anatomical and functional changes of the heart can easily be detected by echocardiography, which is a safe and readily available study. Objectives: The aims of this study were to evaluate the prevalence of common echocardiographic changes in chronic hypertensive patients and to compare these changes in male and female populations. Design/methods: The study was a community-based cross-sectional study, on 227 hypertensive patients, 60 years and older, seen in St...
January 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/28633742/cutaneous-varicella-zoster-virus-infection-following-zoster-vaccination-report-of-post-vaccination-herpes-zoster-skin-infection-and-literature-review-of-zoster-vaccination-efficacy-and-guidelines
#3
Katherine M Stiff, Philip R Cohen
BackgroundHerpes zoster vaccine is currently recommended in the United States for immune competent individuals ≥60 years. The efficacy of the herpes zoster vaccine decreases with age and with time following vaccination.PurposeAn elderly man with herpes zoster following vaccination is described. The guidelines for vaccination and issues regarding re-vaccination are reviewed. METHODS: PubMed was used to search the following terms: efficacy, elderly, herpes zoster, herpes zoster incidence, herpes zoster recurrence, and vaccination...
June 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28633519/changes-in-abdominal-aortic-aneurysm-epidemiology
#4
Fredrik Lilja, Anders Wanhainen, Kevin Mani
INTRODUCTION: The epidemiology and treatment of abdominal aortic aneurysms (AAA) has changed over the past 30 years. EVIDENCE ACQUISITION: This review aims to give the reader an overview of these changes and current trends in AAA epidemiology, management and outcome. EVIDENCE SYNTHESIS: In the past decades there have been three changes in AAA management and epidemiology: a) introduction of endovascular aortic repair (EVAR), b) population screening and c) a markedly reduced prevalence of the disease...
June 20, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28633440/low-alanine-aminotransferase-levels-in-the-elderly-frailty-disability-sarcopenia-and-reduced-survival
#5
Umberto Vespasiani-Gentilucci, Antonio De Vincentis, Luigi Ferrucci, Stefania Bandinelli, Raffaele Antonelli Incalzi, Antonio Picardi
Background: Although low alanine aminotransferase (ALT) levels have been associated with poor outcomes in the elderly, the determinants subtending this association have been poorly explored. To gain insight into this topic, we analyzed data from a prospective population-based database (InCHIANTI study) in which frailty, disability, sarcopenia and pyridoxine levels were systematically assessed. Methods: Data are from 765 participants aged >65 years (mean age 75...
June 19, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28633404/agreement-between-35-published-frailty-scores-in-the-general-population
#6
Gloria A Aguayo, Anne-Françoise Donneau, Michel T Vaillant, Anna Schritz, Oscar H Franco, Saverio Stranges, Laurent Malisoux, Michèle Guillaume, Daniel R Witte
In elderly populations, frailty is associated with higher mortality risk. Although many frailty scores (FS) have been proposed, no single score is considered the gold standard. We aimed to evaluate the agreement between a wide range of FS in the English Longitudinal Study of Ageing (ELSA). Through a literature search, we identified 35 FS that could be calculated in ELSA wave 2 (2004-2005). We examined agreement between each frailty score and the mean of 35 FS, using a modified Bland-Altman model and Cohen's kappa (κ)...
June 15, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28633374/cohort-study-of-preoperative-blood-pressure-and-risk-of-30-day-mortality-after-elective-non-cardiac-surgery
#7
S Venkatesan, P R Myles, H J Manning, A M Mozid, C Andersson, M E Jørgensen, J G Hardman, S R Moonesinghe, P Foex, M Mythen, M P W Grocott, R D Sanders
Background: Preoperative blood pressure (BP) thresholds associated with increased postoperative mortality remain unclear. We investigated the relationship between preoperative BP and 30-day mortality after elective non-cardiac surgery. Methods: We performed a cohort study of primary care data from the UK Clinical Practice Research Datalink (2004-13). Parsimonious and fully adjusted multivariable logistic regression models, including restricted cubic splines for numerical systolic and diastolic BP, for 30-day mortality were constructed...
June 15, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28632192/coverage-and-influencing-determinants-of-influenza-vaccination-in-elderly-patients-in-a-country-with-a-poor-vaccination-implementation
#8
Maria Ganczak, Karolina Gil, Marcin Korzeń, Marta Bażydło
The seasonal influenza vaccination uptake of the elderly in Poland is one of the lowest in Europe. Objective: to assess the vaccination coverage and influencing determinants in patients ≥65 years of age. METHODS: A cross-sectional study was conducted (November 2015-April 2016) among consecutive patients admitted to a municipal hospital located in the city of Szczecin, North-west Poland. Patients completed researcher-administered, anonymous questionnaires on socio- demographic data/factors related to the vaccination...
June 20, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28632038/spatial-navigation-deficits-in-amnestic-mild-cognitive-impairment-with-neuropsychiatric-comorbidity
#9
Roxanne C Keynejad, Hana Marková, Kamila Šiffelová, Naveen Kumar, Kamil Vlček, Jan Laczó, Ellen M Migo, Jakub Hort, Michael D Kopelman
AIMS: To find out whether neuropsychiatric comorbidity (comMCI) influences spatial navigation performance in amnestic mild cognitive impairment (aMCI). METHODS: We recruited aMCI patients with (n = 21) and without (n = 21) neuropsychiatric comorbidity or alcohol abuse, matched for global cognitive impairment and cognitively healthy elderly participants (HE, n = 22). They completed the Mini-Mental State Examination and a virtual Hidden Goal Task in egocentric, allocentric, and delayed recall subtests...
February 28, 2017: Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
https://www.readbyqxmd.com/read/28631805/drug-therapy-for-chronic-idiopathic-axonal-polyneuropathy
#10
REVIEW
Janna Warendorf, Alexander Fje Vrancken, Ivo N van Schaik, Richard Ac Hughes, Nicolette C Notermans
BACKGROUND: Chronic idiopathic axonal polyneuropathy (CIAP) is an insidiously progressive sensory or sensorimotor polyneuropathy that affects elderly people. Although severe disability or handicap does not occur, CIAP reduces quality of life. CIAP is diagnosed in 10% to 25% of people referred for evaluation of polyneuropathy. There is a need to gather and review emerging evidence on treatments, as the number of people affected is likely to increase in ageing populations. This is an update of a review first published in 2004 and previously updated in 2006, 2008, 2011 and 2013...
June 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28631524/the-association-between-social-jetlag-the-metabolic-syndrome-and-type-2-diabetes-mellitus-in-the-general-population-the-new-hoorn-study
#11
Anitra D M Koopman, Simone P Rauh, Esther van 't Riet, Lenka Groeneveld, Amber A van der Heijden, Petra J Elders, Jacqueline M Dekker, Giel Nijpels, Joline W Beulens, Femke Rutters
Only a few studies have investigated the metabolic consequences of social jetlag. Therefore, we examined the association of social jetlag with the metabolic syndrome and type 2 diabetes mellitus in a population-based cohort. We used cross-sectional data from the New Hoorn Study cohort ( n = 1585, 47% men, age 60.8 ± 6 years). Social jetlag was calculated as the difference in midpoint sleep (in hours) between weekdays and weekend days. Poisson and linear regression models were used to study the associations, and age was regarded as a possible effect modifier...
June 1, 2017: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/28631285/quality-assurance-of-falls-reduction-in-an-orthopaedic-ward-using-a-novel-bedside-trolley-table-set-up-strategy
#12
Shuang Quan Chan, Marianne Wadsley, Sue Ferriere
OBJECTIVE: To assess whether a novel bedside trolley table set-up decreased inpatient falls (IF) postintervention. METHODS: From December 2012 to December 2014, geriatric patients admitted to our orthopaedic ward with extreme falls risk had a bedside trolley placed between them and a floor sensor mat to give responders more time to prevent IF. Pre- and postintervention falls data was reviewed for falls reduction using falls per month as comparison standard. IF were classified as high or low/medium risk using St Thomas's Risk Assessment Tool In Falling Elderly inpatients (STRATIFY) scoring...
June 20, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28631181/glaucoma-awareness-amongst-glaucoma-patients-seeking-a-second-opinion
#13
Devindra Sood, Shivam Sood, Ishaana Sood, Dinesh Kumar, Rajeev Sood, Narender Nath Sood
PURPOSE: The aim of the study was to assess level of glaucoma awareness amongst glaucoma patients by studying characteristics amongst urban and rural glaucoma populations in North India. METHODS: A questionnaire was designed and administered after appropriate validation amongst patients to identify determinants of glaucoma awareness. Trained personnel delivered the 11 questions to 1506 patients, aged 18 and above through random sampling. The questionnaire evaluated source of awareness, education, gender, location and age on the level of awareness of glaucoma...
June 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28631057/diabetes-mellitus-a-risk-factor-for-seizures-in-the-elderly-a-population-based-study
#14
Marta Baviera, Maria Carla Roncaglioni, Mauro Tettamanti, Tommaso Vannini, Ida Fortino, Angela Bortolotti, Luca Merlino, Ettore Beghi
AIMS: To evaluate the association between diabetes mellitus (DM) and risk of seizures in a well-defined elderly population. METHODS: The administrative databases of the Lombardy region (a 10 million population area in Northern Italy) were used to identify persons aged 65 years or older with DM (defined by prescription of antidiabetic drugs and/or through ICD-9 CM code and/or exemption code for diabetes) during the year 2002. Seizure-free DM subjects were followed until 2012 in search of individuals with incident seizures (identified through ICD-9 CM codes for epilepsy/seizures or ATC codes for antiepileptic drugs associated with the prescription of an electroencephalogram)...
June 19, 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/28630771/polypharmacy-among-underserved-older-african-american-adults
#15
Mohsen Bazargan, James Smith, Masoud Movassaghi, David Martins, Hamed Yazdanshenas, Seyede Salehe Mortazavi, Gail Orum
The purpose of the present study was to examine correlates of polypharmacy among underserved community-dwelling older African American adults. Methods. This study recruited 400 underserved older African Americans adults living in South Los Angeles. The structured face-to-face interviews collected data on participants' characteristics and elicited data pertaining to the type, frequency, dosage, and indications of all medications used by participants. Results. Seventy-five and thirty percent of participants take at least five and ten medications per day, respectively...
2017: Journal of Aging Research
https://www.readbyqxmd.com/read/28630761/partial-proximal-tibia-fractures
#16
Michael J Raschke, Christoph Kittl, Christoph Domnick
Partial tibial plateau fractures may occur as a consequence of either valgus or varus trauma combined with a rotational and axial compression component.High-energy trauma may result in a more complex and multi-fragmented fracture pattern, which occurs predominantly in young people. Conversely, a low-energy mechanism may lead to a pure depression fracture in the older population with weaker bone density.Pre-operative classification of these fractures, by Müller AO, Schatzker or novel CT-based methods, helps to understand the fracture pattern and choose the surgical approach and treatment strategy in accordance with estimated bone mineral density and the individual history of each patient...
May 2017: EFORT open reviews
https://www.readbyqxmd.com/read/28629695/a-controlled-study-of-the-influence-of-comorbidity-on-activities-of-daily-living-in-elderly-cancer-survivors-the-hunt-3-survey
#17
Ellen Karine Grov, Sophie D Fosså, Alv A Dahl
OBJECTIVES: To examine the influence of somatic comorbidity on Activity of Daily Living (ADL) problems in cancer survivors ≥70years (ECSs) based on data from The Health Study of Nord-Trøndelag County (HUNT-3) 2006-08. MATERIAL AND METHODS: Among participants of the HUNT-3 survey, 599 ECSs had a diagnosis of one invasive cancer according to both The Cancer Registry of Norway and self-report. Three controls without cancer aged ≥70years for each ECS were drawn from the HUNT-3 sample...
June 16, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/28629510/screening-strategies-for-atrial-fibrillation-a-systematic-review-and-cost-effectiveness-analysis
#18
Nicky J Welton, Alexandra McAleenan, Howard Hz Thom, Philippa Davies, Will Hollingworth, Julian Pt Higgins, George Okoli, Jonathan Ac Sterne, Gene Feder, Diane Eaton, Aroon Hingorani, Christopher Fawsitt, Trudie Lobban, Peter Bryden, Alison Richards, Reecha Sofat
BACKGROUND: Atrial fibrillation (AF) is a common cardiac arrhythmia that increases the risk of thromboembolic events. Anticoagulation therapy to prevent AF-related stroke has been shown to be cost-effective. A national screening programme for AF may prevent AF-related events, but would involve a substantial investment of NHS resources. OBJECTIVES: To conduct a systematic review of the diagnostic test accuracy (DTA) of screening tests for AF, update a systematic review of comparative studies evaluating screening strategies for AF, develop an economic model to compare the cost-effectiveness of different screening strategies and review observational studies of AF screening to provide inputs to the model...
May 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28629413/progressive-disability-in-elderly-population-among-tribals-of-telangana-a-cross-sectional-study
#19
Ajitha Katta, Anil Kumar Indira Krishna, Bagavandas M, Tomofumi Anegawa, Suresh Munuswamy
BACKGROUND: The tribal population of Telangana, India, lives in remote and difficult conditions. This study was carried out to find out estimate, the prevalence and progression of disability in elderly population among tribals of Khammam District, Telangana state, India. METHODS: A population based cross sectional survey was conducted in villages of Tribal Sub Plan area. Elderly people who are 60 years or older were chosen with a two stage sampling procedure: (1) probability proportion to size was used to select clusters and (2) in each selected cluster households were selected by systematic random sampling...
June 19, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28629376/radiation-therapy-for-older-patients-with-brain-tumors
#20
REVIEW
Giuseppe Minniti, Andrea Riccardo Filippi, Mattia Falchetto Osti, Umberto Ricardi
The incidence of brain tumors in the elderly population has increased over the last few decades. Current treatment includes surgery, radiotherapy and chemotherapy, but the optimal management of older patients with brain tumors remains a matter of debate, since aggressive radiation treatments in this population may be associated with high risks of neurological toxicity and deterioration of quality of life. For such patients, a careful clinical status assessment is mandatory both for clinical decision making and for designing randomized trials to adequately evaluate the optimal combination of radiotherapy and chemotherapy...
June 19, 2017: Radiation Oncology
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