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https://www.readbyqxmd.com/read/28741198/significance-of-body-mass-index-for-postoperative-outcomes-after-lung-cancer-surgery-in-elderly-patients
#1
Katsunari Matsuoka, Tetsu Yamada, Takahisa Matsuoka, Shinjiro Nagai, Mitsuhiro Ueda, Yoshihiro Miyamoto
BACKGROUND: Although the frequency of elderly patients undergoing surgery for lung cancer has been increasing, indications for surgery in elderly patients are still controversial. Low body mass index is a significant predictor of poor prognosis in elderly patients with various medical conditions. Then, we examined the long-term outcome of elderly patients who had undergone thoracic surgery for lung cancer, focusing especially on body mass index. PATIENTS AND METHODS: Between January 2004 and March 2011, 1673 patients with lung cancer underwent surgical resection at our institution...
July 24, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28739539/medication-reviews-bridging-healthcare-medbridge-study-protocol-for-a-pragmatic-cluster-randomised-crossover-trial
#2
Thomas G H Kempen, Maria Bertilsson, Karl-Johan Lindner, Johanna Sulku, Elisabet I Nielsen, Angelica Högberg, Tomas Vikerfors, Håkan Melhus, Ulrika Gillespie
BACKGROUND: Mismanaged prescribing and use of medication among elderly puts major pressure on current healthcare systems. Performing a medication review, a structured critical examination of a patient's medications, during hospital stay with active follow-up into primary care could optimise treatment benefit and minimise harm. However, a lack of high quality evidence inhibits widespread implementation. This manuscript describes the rationale and design of a pragmatic cluster-randomised, crossover trial to fulfil this need for evidence...
July 21, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28738364/risk-factors-for-community-acquired-pneumonia-in-adults-a-systematic-review-of-observational-studies
#3
Jordi Almirall, Mateu Serra-Prat, Ignasi Bolíbar, Valentina Balasso
We performed a systematic review of the literature to establish conclusive evidence of risk factors for community-acquired pneumonia (CAP). Observational studies (cross-sectional, case-control, and cohort studies) the primary outcome of which was to assess risk factors for CAP in both hospitalized and ambulatory adult patients with radiologically confirmed pneumonia were selected. The Newcastle-Ottawa Scale specific for cohort and case-control designs was used for quality assessment. Twenty-nine studies (20 case-control, 8 cohort, and 1 cross-sectional) were selected, with 44...
July 25, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28735916/morbidity-and-mortality-of-middle-aged-and-elderly-narcoleptics
#4
Poul Jennum, Eva Wiberg Thorstensen, Line Pickering, Rikke Ibsen, Jakob Kjellberg
OBJECTIVES: The objective of the study was to evaluate the morbidities and mortality in a national group of middle-aged and elderly narcolepsy patients before and after the first diagnosis of the condition. METHODS: From the Danish National Patient Registry (NPR), 1174 patients (45.1% males) aged 20-59 years and 339 patients (44.8% males) aged 60+ who received a diagnosis of narcolepsy between 1998 and 2014 were compared, respectively, with 4716 and 1353 control citizens matched for age, gender and geography, who were randomly chosen from the Danish Civil Registration System Statistics...
August 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28716352/fatal-and-non-fatal-injury-outcomes-results-from-a-purposively-sampled-census-of-seven-rural-subdistricts-in-bangladesh
#5
Olakunle Alonge, Priyanka Agrawal, Abu Talab, Qazi S Rahman, Akm Fazlur Rahman, Shams El Arifeen, Adnan A Hyder
BACKGROUND: 90% of the global burden of injuries is borne by low-income and middle-income countries (LMICs). However, details of the injury burden in LMICs are less clear because of the scarcity of data and population-based studies. The Saving of Lives from Drowning project, implemented in rural Bangladesh, did a census on 1·2 million people to fill this gap. This Article describes the epidemiology of fatal and non-fatal injuries from the study. METHODS: In this study, we used data from the baseline census conducted as part of the Saving of Lives from Drowning (SoLiD) project...
August 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28713629/abducent-nerve-palsy-after-microballoon-compression-of-the-trigeminal-ganglion-case-report
#6
Cassiano Marchi, Paulo Henrique Pires de Aguiar, Ana Maria Moura, Giovanna Matricardi, Carolina Utsunomya Muniz, Rogério Aires, Flávia Gehrke, Natally Santiago, Samuel Simis
BACKGROUND: Trigeminal neuralgia (TN) is the most common type of facial neuralgia with incidence of 26.8/100,000 person year. In general, this scenario is characterized by a lancinating, unilateral, paroxysmal pain in the area of the fifth cranial nerve. Several treatment methods, including the injection of ethyl alcohol or butyl alcohol into the ganglion, the glycerol injection into the trigeminal cistern, peripheral nerve divisions, the radiofrequency thermocoagulation of the preganglionic fibers, and radiosurgery has been used for TN...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28708957/influenza-vaccination-in-the-elderly
#7
Smetana Jan, Chlibek Roman, Shaw Jana, Splino Miroslav, Prymula Roman
Seasonal influenza is a prevalent and serious annual illness resulting in widespread morbidity and economic disruption throughout the population; the elderly and immunocompromised are particularly vulnerable to serious sequelae and mortality. The changing demographics worldwide to an aging society have important implications for public health policy and pharmaceutical innovations. For instance, primary prevention via immunization is effective in reducing the burden of influenza illness among the elderly. However, the elderly may be insufficiently protected by vaccination due to the immunosenescence which accompanies aging...
July 14, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28705276/evaluation-of-autoimmune-bullous-diseases-in-elderly-patients-in-iran-a-10-year-retrospective-study
#8
Maryam Ghiasi, Maryam Daneshpazhooh, Muhammadkhuja Ismonov, Cheyda Chams-Davatchi
Autoimmune bullous diseases (ABDs) are uncommon but significant skin disorders with relatively high morbidity and mortality. Some surveys have been carried out to describe the spectrum of ABDs in a region, but this is the first that has focused on ABDs in elderly patients. This study was conducted to determine the clinicoepidemiologic features of ABDs in elderly patients. Medical records of all ABD patients with disease onset after the age of 60 years who presented to the Autoimmune Bullous Diseases Research Center, Tehran, Iran between April 2003 and March 2013 were reviewed...
2017: Skinmed
https://www.readbyqxmd.com/read/28700591/trends-in-traumatic-brain-injury-mortality-in-china-2006-2013-a-population-based-longitudinal-study
#9
Peixia Cheng, Peng Yin, Peishan Ning, Lijun Wang, Xunjie Cheng, Yunning Liu, David C Schwebel, Jiangmei Liu, Jinlei Qi, Guoqing Hu, Maigeng Zhou
BACKGROUND: Traumatic brain injury (TBI) is a significant global public health problem, but has received minimal attention from researchers and policy-makers in low- and middle-income countries (LMICs). Epidemiological evidence of TBI morbidity and mortality is absent at the national level for most LMICs, including China. Using data from China's Disease Surveillance Points (DSPs) system, we conducted a population-based longitudinal analysis to examine TBI mortality, and mortality differences by sex, age group, location (urban/rural), and external cause of injury, from 1 January 2006 to 31 December 2013 in China...
July 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28695390/impact-of-patient-age-on-the-postoperative-survival-in-pancreatic-head-cancer
#10
Teiichi Sugiura, Y Okamura, T Ito, Y Yamamoto, R Ashida, K Uesaka
BACKGROUND: Some reports have stated that pancreatoduodenectomy for elderly patients have comparable morbidity and mortality to that of young patients. However, the long-term outcomes of these patients have not been fully evaluated, especially for pancreatic head cancer. METHODS: A total of 227 patients who underwent pancreatoduodenectomy for pancreatic head cancer between 2007 and 2014 were included. They were stratified according to age: young (<70 years), elderly (70 to <80 years), and very elderly (≥80 years)...
July 10, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28694824/burden-and-correlates-of-falls-among-rural-elders-of-south-india-mobility-and-independent-living-in-elders-study
#11
Pawan Kumar Sharma, Clareann H Bunker, Tushar Singh, Enakshi Ganguly, P Sudhakar Reddy, Anne B Newman, Jane A Cauley
AIM: Falls are an important contributor to loss of function, morbidity, and mortality in elders. Little is known about falls in Indian populations. The objective of this cross-sectional report was to identify the prevalence and correlates of falls in a cohort of 562 rural southern Indian men and women. METHODS: Risk factors included demographics, anthropometrics, self-reported health, medical history, physical function, vision, depression, and lifestyle. Odds ratios were calculated using logistic regression...
2017: Current Gerontology and Geriatrics Research
https://www.readbyqxmd.com/read/28693251/clinical-features-and-surgical-management-of-intracranial-meningiomas-in-the-elderly
#12
Junkoh Yamamoto, Mayu Takahashi, Masaru Idei, Yoshiteru Nakano, Yoshiteru Soejima, Daisuke Akiba, Takehiro Kitagawa, Kunihiro Ueta, Ryo Miyaoka, Shigeru Nishizawa
Meningioma accounts for ~25% of all primary intracranial neoplasms and the incidence increases with age. Prvios population-based studies demonstrated that the annual incidence of intracranial meningiomas was 1.2-3.1/100,000 population. In particular, the incidence of this disease among the elderly is high. Recently, increased life expectancy and greater use of diagnostic radiological imaging led to an increased incidence in the diagnosis of intracranial meningiomas, both symptomatic and asymptomatic, in the elderly...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28688634/predictors-of-mortality-in-the-elderly-after-open-repair-for-perforated-peptic-ulcer-disease
#13
Vijaya T Daniel, Jason T Wiseman, Julie Flahive, Heena P Santry
BACKGROUND: As the U.S. population ages and the number of emergent surgical repairs for perforated peptic ulcer disease (PUD) rise, contemporary national data evaluating operative outcomes for open surgical repair for perforated PUD among the elderly are lacking. MATERIALS AND METHODS: The National Surgical Quality Improvement Program (2007-2014) was queried for patients ≥65 y who underwent open surgical repair for perforated PUD. The primary outcome was 30-d mortality...
July 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28686603/association-between-elder-abuse-and-poor-sleep-a-cross-sectional-study-among-rural-older-malaysians
#14
Raudah Mohd Yunus, Syeda Wasfeea Wazid, Noran N Hairi, Wan Yuen Choo, Farizah M Hairi, Rajini Sooryanarayana, Sharifah N Ahmad, Inayah A Razak, Devi Peramalah, Suriyati A Aziz, Zaiton L Mohamad, Rosmala Mohamad, Zainudin M Ali, Awang B Awang Mahmud
OBJECTIVES: To examine the association between elder abuse and poor sleep using a Malay validated version of Pittsburgh Sleep Quality Index (PSQI). DESIGN: This study was divided into two phases. Phase I tested the construct validity and reliability of the Malay version of PSQI. Phase II was a population-based, cross-sectional study with a multi-stage cluster sampling method. Home-based interviews were conducted by trained personnel using a structured questionnaire, to determine exposure and outcome...
2017: PloS One
https://www.readbyqxmd.com/read/28681427/delirium-after-fast-track-hip-and-knee-arthroplasty-a-cohort-study-of-6331-elderly-patients
#15
P B Petersen, C C Jørgensen, H Kehlet
BACKGROUND: Postoperative delirium (PD) is a well-known complication among elderly surgical patients and associated with increased morbidity, mortality and length of stay (LOS). In elective orthopedic surgery, including hip and knee arthroplasty (THA/TKA), most studies report incidences between 5% and 10%. The multimodal optimization of perioperative care (fast-track) aims to enhance recovery and reduce morbidity and LOS, but limited data are available on the effect on PD. Consequently, the study investigated signs of PD associated with LOS > 4 days...
August 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28661104/-laparoscopic-sleeve-gastrectomy-in-the-elderly
#16
REVIEW
Eyal Leiboivtz, Olga Rubalski, Mordechai Shimonov
Obesity is an independent predictor of mortality, especially among patients suffering from chronic illnesses. Basically, obesity occurs as a result of an imbalance between the amount of food consumed and the energy expenditure of a person. Obesity treatment is aimed at creating a new imbalance of reduced food intake and increased energy expenditure. However, diet consultation and physical exercise have failed in the treatment of the majority of obese individuals. Surgical treatment (i.e. bariatric surgery) is aimed at reducing the amount of calories a patient can consume, and is the best treatment for weight reduction to date, and the only proven treatment for morbidly obese individuals...
June 2017: Harefuah
https://www.readbyqxmd.com/read/28658883/artificial-neural-network-ann-model-to-predict-depression-among-geriatric-population-at-a-slum-in-kolkata-india
#17
Arkaprabha Sau, Ishita Bhakta
INTRODUCTION: Depression is one of the most important causes of mortality and morbidity among the geriatric population. Although, the aging brain is more vulnerable to depression, it cannot be considered as physiological and an inevitable part of ageing. Various sociodemographic and morbidity factors are responsible for the depression among them. Using Artificial Neural Network (ANN) model depression can be predicted from various sociodemographic variables and co morbid conditions even at community level by the grass root level health care workers...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28656167/epidemiological-profile-of-extremity-fractures-and-dislocations-in-road-traffic-accidents-in-kashan-iran-a-glance-at-the-related-disabilities
#18
Mehrdad Mahdian, Mohammad R Fazel, Mojtaba Sehat, Gholamreza Khosravi, Mahdi Mohammadzadeh
BACKGROUND: Apart from the mortality, road traffic injuries are associated with significant morbidities. This study has aimed to examine the pattern of traffic accident-related extremity fractures/dislocations and their related disabilities. METHODS: A retrospective hospital-based study was conducted to assess the characteristics of limb fractures/dislocations among road traffic accident victims registered in Trauma Research Center registry of Kashan University of Medical Sciences, Kashan, Iran, during 2012-2013...
May 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/28656076/effects-of-age-on-survival-and-morbidity-in-gastric-cancer-patients-undergoing-gastrectomy
#19
Yoshinori Fujiwara, Shuichi Fukuda, Masanori Tsujie, Hajime Ishikawa, Kotaro Kitani, Keisuke Inoue, Masao Yukawa, Masatoshi Inoue
AIM: To evaluate clinicopathological features and surgical outcomes of gastric cancer in elderly and non-elderly patients after inverse probability of treatment weighting (IPTW) method using propensity score. METHODS: We enrolled a total of 448 patients with histologically confirmed primary gastric carcinoma who received gastrectomies. Of these, 115 patients were aged > 80 years old (Group A), and 333 patients were aged < 79 years old (Group B). We compared the surgical outcomes and survival of the two groups after IPTW...
June 15, 2017: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28650104/alzheimer-s-disease-and-metabolic-syndrome-a-link-from-oxidative-stress-and-inflammation-to-neurodegeneration
#20
REVIEW
Eduardo Rojas-Gutierrez, Guadalupe Muñoz-Arenas, Samuel Treviño, Blanca Espinosa, Raúl Chavez, Karla Rojas, Gonzalo Flores, Alfonso Díaz, Jorge Guevara
Alzheimer's disease (AD) is the most common cause of dementia and one of the most important causes of morbidity and mortality among the aging population. AD diagnosis is made post-mortem, and the two pathologic hallmarks, particularly evident in the end stages of the illness, are amyloid plaques and neurofibrillary tangles (NFT). Currently, there is no curative treatment for AD. Additionally, there is a strong relation between oxidative stress, metabolic syndrome (MetS) and AD. The high levels of circulating lipids and glucose imbalances amplify lipid peroxidation that gradually diminishes the antioxidant systems, causing high levels of oxidative metabolism that affects cell structure, leading to neuronal damage...
June 26, 2017: Synapse
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