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https://www.readbyqxmd.com/read/28317486/abnormal-clock-gene-expression-and-locomotor-activity-rhythms-in-two-month-old-female-appswe-ps1de9-mice
#1
Olaide Oyegbami, Hilary M Collins, Marie C Pardon, Fran Jp Ebling, David M Heery, Paula M Moran
In addition to cognitive decline, Alzheimer's disease (AD) is also characterized by agitation and disruptions in activity and sleep. These symptoms typically occur in the evening or at night and have been referred to as 'sundowning'. These symptoms are especially difficult for carers and there are no specific drug treatments. There is increasing evidence that these symptoms reflect an underlying pathology of circadian rhythm generation and transmission. We investigated whether a transgenic mouse model relevant to AD (APPswe/PS1dE9) exhibits circadian alterations in locomotor activity and expression of clock genes involved in the regulation of the circadian cycle...
March 17, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28315857/risk-factors-for-overweight-and-obesity-in-children-aged-2-6-years
#2
Meda Kondolot, Serpil Poyrazoğlu, Duygu Horoz, Arda Borlu, Canan Altunay, Elcin Balcı, Ahmet Öztürk, Mümtaz M Mazıcıoğlu, Selim Kurtoğlu
BACKGROUND: Understanding risk factors that may vary culturally can help improve preventive strategies for obesity. This is the first cross-sectional study aimed to determine the risk factors for overweight/obesity in children aged 2-6 years in a central Anatolian city in Turkey. METHODS: A total of 1582 children (1351 healthy, 231 overweight/obese) aged 2-6 years were included from the Anthropometry of Turkish Children aged 0-6 years database. Age, gender, birth weight, birth order, mother's age, mother's body mass index (BMI), weight gain of mothers during pregnancy, presence of gestational diabetes, breastfeeding duration, history of formula feeding, mother's and father's education, mother's job, monthly income, smoking at home and physical activity, sleep duration and duration of television (TV) watching of the children were evaluated as independent risk factors...
March 18, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28286813/risk-factors-of-non-fatal-unintentional-home-injuries-among-children-under-5-years-old-a-population-based-study
#3
Sedigheh Nouhjah, Sharareh R Niakan Kalhori, Azadeh Saki
INTRODUCTION: In addition to the annual mortality rate, unintentional home injury may result in temporary or permanent disability and requires medical attention and continuous care in millions of children. This study aimed to explore features and risk factors of these injuries. METHODS: In this cross-sectional study, demographic variables and epidemiologic pattern of home injuries among children under 5 years of age were collected via a population-based survey in seven main cities of Khuzestan province, southwest Iran, during September 2011 to December 2012...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28276143/experiences-and-needs-of-spouses-of-persons-with-young-onset-frontotemporal-lobe-dementia-during-the-progression-of-the-disease
#4
Aud Johannessen, Anne-Sofie Helvik, Knut Engedal, Kirsten Thorsen
BACKGROUND: Two of the most common types of young-onset dementia (<65 years old) are Alzheimer's disease and frontotemporal lobe dementia (FTLD). A limited amount of research that focuses on the needs of spouses of persons with young-onset FTLD (yo-FTLD) has been published. Thus, we have carried out a study aiming to examine the spouses of yo-FTLD experiences and needs for assistance in daily life. METHOD: Qualitative interviews with 16 informants (aged 51-69 years; nine wives, six husbands and one male cohabitant) were conducted in 2014 and 2015...
March 9, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/28276132/profiles-of-alzheimer-s-caregivers-in-spain-social-educational-and-laboral-characteristics
#5
Manuel Ruiz-Adame Reina, María Carmen González-Camacho, José Enrique Romero-García, Luís María Sánchez-Reyes Fernández
BACKGROUND: A person suffering from dementia needs increasing help from another person, who, in most cases, is a female family member. Times are changing and this traditional role can no longer be maintained. AIM: The aim of this research was mainly centred on ascertaining the profile of caregivers and to find out how determinants such as age, sex and educational level and living conditions led people to assume that role. METHODS: A survey was designed and applied to 925 caregivers (778 of which were analysed) with the collaboration of the Alzheimer's Associations of Andalucía (Spain)...
March 9, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/28274649/development-of-a-new-in-home-testing-method-to-assess-infant-food-liking
#6
J Madrelle, C Lange, I Boutrolle, O Valade, H Weenen, S Monnery-Patris, S Issanchou, S Nicklaus
The objective of this study was to develop a new elaborate method to evaluate infants' liking of foods that could be applied at home and to compare the results of this elaborate method with those of a basic method. Mothers of infants aged 4 to 7 (n = 44) and 12-15 months (n = 46) participated in this study. For the basic method, mothers were asked to assess their infant's global liking at the end of a meal. Then, for the elaborate method, mothers received detailed instructions on how to feed their infant, how infants might express like/dislike and when to stop the meal...
March 6, 2017: Appetite
https://www.readbyqxmd.com/read/28271911/physical-function-of-elderly-patients-with-multimorbidity-upon-acute-hospital-admission-versus-3%C3%A2-weeks-post-discharge
#7
Kjersti Moen, Heidi Ormstad, Marte Sofie Wang-Hansen, Therese Brovold
PURPOSE: To evaluate the change in activities of daily living, grip strength and functional mobility in very old patients >75 years old with multimorbidity upon admission to hospital versus 3 weeks after discharge. A second aim was to explore which baseline variables could predict personal activities of daily living 3 weeks after discharge. METHODS: This prospective cohort study included 115 home-dwelling older adults (mean 86 years, standard deviation 5...
March 8, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28265411/outcomes-of-an-inpatient-medical-nutritional-rehabilitation-protocol-in-children-and-adolescents-with-eating-disorders
#8
Rebecka Peebles, Andrew Lesser, Courtney Cheek Park, Kerri Heckert, C Alix Timko, Eleni Lantzouni, Ronald Liebman, Laurel Weaver
BACKGROUND: Medical stabilization through inpatient nutritional rehabilitation is often necessary for patients with eating disorders (EDs) but includes the inherent risk of refeeding syndrome. Here we describe our experience of implementing and sustaining an inpatient nutritional rehabilitation protocol designed to strategically prepare patients with EDs and their families for discharge to a home setting in an efficient and effective manner from a general adolescent medicine unit. We report outcomes at admission, discharge, and 4-weeks follow-up...
2017: Journal of Eating Disorders
https://www.readbyqxmd.com/read/28261577/self-reported-perceptions-of-weight-and-eating-behavior-of-school-children-in-sunderland-england
#9
REVIEW
Alison McInnes, David Blackwell
The main aim of this study was to determine the self-reported perceptions of weight and eating behaviors of school-age children in Sunderland in the North East of England. The results presented are derived from data collected by a Health-Related Behaviour Survey developed by Schools and Students Health Education Unit at Exeter University, and this study is based on analysis of the data set collected for Sunderland. A total of 12,213 pupils from nine secondary schools completed the questionnaire biennially from 1996 to 2012...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28259339/the-influence-of-parental-self-efficacy-and-perceived-control-on-the-home-learning-environment-of-young-children
#10
Elizabeth Peacock-Chambers, Justin T Martin, Kelly A Necastro, Howard J Cabral, Megan Bair-Merritt
OBJECTIVE: To: 1) examine sociodemographic factors associated with high parental self-efficacy and perceived control, and 2) determine how self-efficacy and control relate to the home learning environment (HLE), including whether they mediate the relationship between sociodemographic characteristics and HLE, among low-income parents of young children. METHODS: Cross-sectional survey of English- and Spanish-speaking parents, 18 years of age and older, with children 15 to 36 months old, to assess parental self-efficacy, perceived control, HLE, and sociodemographic characteristics...
March 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/28255548/rapunzel-syndrome-is-not-just-a-mere-surgical-problem-a-case-report-and-review-of-current-management
#11
Obinna Obinwa, David Cooper, Faraz Khan, James M O'Riordan
Recurrent Rapunzel syndrome (RRS) is a rare clinical presentation with fewer than six cases reported in the PubMed literature. A report of RRS and literature review is presented. A 25-year-old female was admitted to hospital with a 4-wk history of epigastric pain and swelling. She had a known history of trichophagia with a previous admission for Rapunzel syndrome requiring a laparotomy nine years earlier, aged 16. Psychological treatment had been successfully achieved for nine years with outpatient hypnotherapy sessions only, but she defaulted on her last session due to stressors at home...
February 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28251570/predictors-of-institutionalization-in-people-with-dementia-a-survey-linked-with-administrative-data
#12
Rebecca Runte
BACKGROUND: For people with dementia, moving into a nursing home is usually considered at some point in time. Currently available information on predictors of institutionalization is often based on small sample sizes, not taking competing risks into account, and with inconclusive results for sex. AIMS: We aimed to carry out an analysis stratified by sex and using a competing risk approach. METHODS: We carried out an analysis of a survey linked with administrative data including 652 people with dementia, aged 60 years and older...
March 1, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28251324/middle-cerebral-artery-aneurysm-rupture-in-a-neonate-with-interrupted-aortic-arch-case-report
#13
Joaquin Hidalgo, James Charles Dickerson, Brandon Burnsed, Ali Luqman, James Mason Shiflett
INTRODUCTION: Arterial cerebral aneurysms in the neonatal population are rare, and while the association of interrupted aortic arch and intracranial aneurysm has been reported in the adult and pediatric population (three cases each), to date, it has not been reported in the neonate. CASE REPORT: We report the case of a 26-day-old girl who presented with a generalized seizure 2 weeks after undergoing congenital heart surgery. Head CT revealed diffuse SAH with a 1...
March 1, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28248782/occupational-exposures-of-home-healthcare-workers
#14
Noma Agbonifo, Beverly Hittle, Rassull Suarez, Kermit Davis
Population demographics in the United States are rapidly changing with increased dependence on home healthcare (HHC) by an aging population, patients suffering from chronic diseases, and inability to perform activities of daily living. Despite the occupational injury rates for HHC workers (HHCW) being higher than the national average, an understanding of the occupational safety and health experiences and exposures of HHCW is limited. The purpose of this study was to understand the health and safety risk factors for HHCW...
March 2017: Home Healthcare Now
https://www.readbyqxmd.com/read/28244563/non-dietary-correlates-and-determinants-of-plasma-lutein-and-zeaxanthin-concentrations-in-the-irish-population
#15
R Moran, J M Nolan, J Stack, A M O'Halloran, J Feeney, K O Akuffo, R A Kenny, S Beatty
OBJECTIVE: To investigate non-dietary correlates and determinants of plasma lutein (L) and zeaxanthin (Z) concentrations in The Irish Longitudinal Study on Ageing (TILDA) sample. DESIGN: Cross-sectional study. SETTING: Community dwelling adults in the Republic of Ireland (ROI). PARTICIPANTS: 3,681 participants aged 50 years and older. MEASUREMENTS: TILDA is a nationally representative prospective cohort study of community dwelling adults aged 50 years and over in the ROI...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28243066/flying-the-nest-a-challenge-for-young-adults-with-cystic-fibrosis-and-their-parents
#16
Vibeke Bregnballe, Kirsten A Boisen, Peter Oluf Schiøtz, Tacjana Pressler, Kirsten Lomborg
OBJECTIVES: As young patients with cystic fibrosis (CF) grow up, they are expected to take increasing responsibility for the treatment and care of their disease. The aim of this study was to explore the disease-related challenges faced by young adults with CF and their parents, when they leave home. MATERIALS AND METHODS: A questionnaire survey of Danish patients with CF aged 18-25 years and their parents was conducted. The questionnaires were based on focus-group interviews with young adults with CF and their parents, and addressed challenges faced in the transition phase between childhood and adulthood, including different areas of disease management in everyday life...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28242238/the-burden-of-facial-cellulitis-leading-to-inpatient-hospitalization
#17
Shelly Abramowicz, Sankeerth Rampa, Veerasathpurush Allareddy, Min Kyeong Lee
PURPOSE: The purpose of the present study was to present nationally representative estimates of hospitalizations primarily attributed to facial cellulitis and to conduct an exploratory analysis on identifying factors associated with outcomes, such as hospital charges, length of stay (LOS), disposition status, and occurrence of infectious complications. MATERIALS AND METHODS: The present study is a retrospective analysis of the Nationwide Inpatient Sample (NIS) for 2012 and 2013...
February 3, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28241994/quality-of-life-and-risk-of-malnutrition-in-a-home-dwelling-population-over-75%C3%A2-years-old
#18
Ana Hernández-Galiot, Isabel Goñi
OBJECTIVES: To evaluate the quality of life of a noninstitutionalized population aged older than 75 y by determining nutritional and health status, and to investigate the relationship between nutritional risk and quality of life. METHODS: A cross-sectional study of elderly people was conducted in Garrucha (Almería) in southern Spain. A total of 102 participants (61 women and 41 men) aged older than 75 y. The Mini Nutritional Assessment test was used to detect nutritional risk...
March 2017: Nutrition
https://www.readbyqxmd.com/read/28231615/what-do-older-people-experiencing-loneliness-think-about-primary-care-or-community-based-interventions-to-reduce-loneliness-a-qualitative-study-in-england
#19
Kalpa Kharicha, Steve Iliffe, Jill Manthorpe, Carolyn A Chew-Graham, Mima Cattan, Claire Goodman, Maggie Kirby-Barr, Janet H Whitehouse, Kate Walters
Loneliness in later life is a common problem with poor health outcomes. However, interventions to prevent or ameliorate loneliness have a weak evidence base. The views of older people experiencing or at risk of loneliness in the community are important in identifying features of potential support, but have been little studied. Twenty-eight community dwelling people, aged 65 and over who reported being 'lonely much of the time' or identified as lonely from the de Jong Gierveld six-item loneliness scale in a larger study, participated in in-depth interviews, between June 2013 and May 2014...
February 23, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28224961/-old-age-and-smoking
#20
Pascal Menecier, Alba Moscato, Lydia Fernandez
Elderly people today have seen a radical change in the image of smokers over the last half century. While once it was approved, it is now demonised. Although smoking declines with age, there are still many elderly smokers. The risks and harm of smoking remain, even in old age. An individual choice to start with, smoking becomes a collective issue in a nursing home. Stopping smoking always brings benefits, even after the age of 80.
January 2017: Soins. Gérontologie
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