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morbidity pattern older people

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https://www.readbyqxmd.com/read/29111259/cancer-incidence-and-mortality-among-young-adults-aged-20-39-years-worldwide-in-2012-a-population-based-study
#1
Miranda M Fidler, Sumit Gupta, Isabelle Soerjomataram, Jacques Ferlay, Eva Steliarova-Foucher, Freddie Bray
BACKGROUND: To date, the burden of cancer among young adults has rarely been studied in depth. Our aim was to describe the scale and profile of cancer incidence and mortality worldwide among 20-39 year-olds, highlighting major patterns by age, sex, development level, and geographical region. METHODS: We did a population-based study to quantify the burden of young adult cancers worldwide. We defined young adult cancers as those occurring between the ages of 20 and 39 years because these individuals will have passed puberty and adolescence, but not yet experienced the effects of hormonal decline, immune response deterioration, or organ dysfunction associated with chronic health conditions...
October 27, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/29073132/patterns-factors-associated-and-morbidity-burden-of-asthma-in-india
#2
Prakash Kumar, Usha Ram
BACKGROUND: Asthma is a non-curable but preventable disease, responsible for higher morbidity worldwide. According to recent WHO report, nearly 235 million people are suffering from asthma leading to 383000 deaths in 2015. The burden of asthma morbidity is higher in developed countries and is increasing in developing countries. OBJECTIVE: The present study was aimed at studying the change in prevalence rate of asthma, associated risk factors and estimation of morbidity burden and avoidable cases of asthma in India...
2017: PloS One
https://www.readbyqxmd.com/read/29060109/physiologically-motivated-detection-of-atrial-fibrillation
#3
R Couceiro, J Henriques, R P Paiva, M Antunes, P Carvalho
Atrial Fibrillation (AF) is the most common arrhythmia and it is estimated to affect 33.5 million people worldwide. AF is associated with an increased risk of mortality and morbidity, such as heart failure and stroke and affects mostly older persons and persons with other conditions (e.g. heart failure and coronary artery disease). In order to prevent such life threatening and life quality reducing conditions it is essential to provide better algorithms, capable of being integrated in low-cost personalized health systems...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29036509/medication-usage-change-in-older-people-65-in-england-over-20-years-findings-from-cfas-i-and-cfas-ii
#4
L Gao, Ian Maidment, Fiona E Matthews, Louise Robinson, Carol Brayne
Background: medical practice has changed over the last decades reflecting the ageing population, when multi-morbidity requiring multiple medications is more common. Objective: describe and quantify self-reported medicine use including both prescription and over the counter medicines in two comparable population-based studies of older people (65+) in England and to assess the nature and scale of polypharmacy. Methods: data used were from two separate population-based studies; the Cognitive Function Ageing Study I and II...
September 26, 2017: Age and Ageing
https://www.readbyqxmd.com/read/29023223/point-prevalence-and-patterns-of-mental-health-comorbidity-among-people-accessing-australia-s-first-older-adult-specific-alcohol-and-other-drug-treatment-service
#5
Stephen Bright, Katherine Walsh, Cylie Williams
OBJECTIVE: There are good data regarding the prevalence and patterns of dual diagnosis among the general population; however, data regarding the older adult cohort are limited. We aimed to extend the knowledge of the point prevalence and patterns of dual diagnosis among older adults and the impact of dual diagnosis on the utilization of alcohol and other drug treatment services. METHOD: A 12-month medical chart audit of clients discharged from an Australian older adult-specific alcohol and other drug treatment service was performed...
October 12, 2017: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/28949827/correlates-of-high-risk-and-low-risk-alcohol-use-among-college-students-in-kerala-india
#6
T S Jaisoorya, Guru S Gowda, B Sivasankaran Nair, Priya G Menon, Anjana Rani, K S Radhakrishnan, M Revamma, C R Jeevan, Anupam Kishore, K Thennarasu, Vivek Benegal
This study describes the prevalence and correlates of alcohol use among college students in Ernakulam, Kerala State, India. A total of 5784 students from 58 colleges selected by stratified random sampling completed a questionnaire incorporating standardized instruments. The prevalence of lifetime alcohol use was 21.4% with a male predominance. Among users, low-risk, hazardous, and dependent use were 80.2%, 18.3% and 0.9% respectively. Initiation was mostly with friends (45.3%). Both low-risk and high-risk alcohol users (hazardous and dependent users), in comparison to abstainers, had higher odds of being older, non-Muslim, having a part-time job, using other substances, and exposure to sexual abuse...
September 26, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28922979/a-review-of-drug-drug-interactions-in-older-hiv-infected-patients
#7
Aarthi Chary, Nancy N Nguyen, Kimberly Maiton, Mark Holodniy
The number of older HIV-infected people is growing due to increasing life expectancies resulting from the use of antiretroviral therapy (ART). Both HIV and aging increase the risk of other comorbidities, such as cardiovascular disease, osteoporosis, and some malignancies, leading to greater challenges in managing HIV with other conditions. This results in complex medication regimens with the potential for significant drug-drug interactions and increased morbidity and mortality. Area covered: We review the metabolic pathways of ART and other medications used to treat medical co-morbidities, highlight potential areas of concern for drug-drug interactions, and where feasible, suggest alternative approaches for treating these conditions as suggested from national guidelines or articles published in the English language...
September 19, 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/28877256/medication-and-supplement-use-in-older-people-with-and-without-intellectual-disability-an-observational-cross-sectional-study
#8
Jure Peklar, Mitja Kos, Máire O'Dwyer, Mary McCarron, Philip McCallion, Rose Anne Kenny, Martin C Henman
INTRODUCTION: Understanding the medication and supplement use of aging people is critical to ensuring that health service providers in primary care can optimise use of these agents. An increasing number of people with different levels of intellectual disability (ID) are living in the community and becoming for the first time substantial users of primary health care services. This, however, brings new challenges that need to be addressed at the primary health care level. We quantified the use of medicines and food supplements and described the associated patterns of morbidity in the two comparable cohorts of aging population with and without intellectual disability...
2017: PloS One
https://www.readbyqxmd.com/read/28777953/sleep-duration-and-its-association-with-demographics-lifestyle-factors-poor-mental-health-and-chronic-diseases-in-older-chinese-adults
#9
Shibin Wang, Yanhua Wu, Gabor S Ungvari, Chee H Ng, Brent P Forester, Jennifer R Gatchel, Helen F K Chiu, Changgui Kou, Yingli Fu, Yue Qi, Yaqin Yu, Bo Li, Yu-Tao Xiang
This study investigated the total sleep time (TST) and its associated factors in an older Chinese adult population. Multistage stratified cluster sampling was used in this cross-sectional study. A total of 4,115 older adults aged 60 to 79 years were selected and interviewed. Sleep duration was classified as short ( 8h per day) and medium sleep (7-8h per day). The total mean sleep time was 6.86±1.75h. Short and long sleepers accounted for 45.2% and 14.8% of the sample, respectively. Multivariate logistic regression analysis revealed that inadequate fruit intake and poor mental health were positively associated with short sleep, and married/cohabitation status and living in rural areas was negatively associated with short sleep...
July 19, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28632340/prescribing-in-the-oldest-old-inpatients-a-retrospective-analysis-of-patients-referred-for-specialist-geriatric-consultation
#10
Sivarajah Ilango, Peter Pillans, Nancye M Peel, Ian Scott, Leonard C Gray, Ruth E Hubbard
INTRODUCTION: While medications may prolong life and prevent morbidity in older people, adverse effects of polypharmacy are increasingly recognised. As patients age and become frail, prescribing may be expected to focus more on symptom control and minimise potentially harmful preventive medication use that confer little benefit within a short lifespan. Whether prescribing practice shifts to one of symptom control among the oldest old admitted to hospital remains unclear. METHODS: Retrospective analysis of all patients aged ≥85 years referred for comprehensive geriatric assessment at a tertiary care hospital between May 2006 and December 2014 for whom all prescribed medications were documented...
June 20, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28601836/contextual-and-individual-inequalities-of-multimorbidity-in-brazilian-adults-a-cross-sectional-national-based-study
#11
Bruno P Nunes, Alexandre D P Chiavegatto Filho, Sanghamitra Pati, Doralice S Cruz Teixeira, Thaynã R Flores, Fabio A Camargo-Figuera, Tiago N Munhoz, Elaine Thumé, Luiz A Facchini, Sandro R Rodrigues Batista
OBJECTIVES: The study aims to evaluate the magnitude of multimorbidity in Brazilian adults, as well to measure their association with individual and contextual factors stratified by Brazilian states and regions. METHODS: A national-based cross-sectional study was carried out in 2013 with Brazilian adults. Multimorbidity was evaluated by a list of 22 physical and mental morbidities (based on self-reported medical diagnosis and Patient Health Questionnaire-9 for depression)...
June 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28510585/the-prevalence-of-underweight-overweight-and-obesity-in-bangladeshi-adults-data-from-a-national-survey
#12
Tuhin Biswas, Sarah P Garnett, Sonia Pervin, Lal B Rawal
BACKGROUND: Over the two last decades Bangladesh, a low-income country, has experienced a rapid demographic and epidemiological transition. The population has increased substantially with rapid urbanization and changing pattern of disease, which at least in part, can be explained by nutritional changes. However, the nutritional status of the adult population has not been previously described. Hence, the objective of this study was to estimate the prevalence and explore socio-demographic determinants of underweight, overweight and obesity among the Bangladeshi adult population...
2017: PloS One
https://www.readbyqxmd.com/read/28506233/measurement-and-decomposition-of-socioeconomic-inequality-in-single-and-multimorbidity-in-older-adults-in-china-and-ghana-results-from-the-who-study-on-global-ageing-and-adult-health-sage
#13
Rasha Kunna, Miguel San Sebastian, Jennifer Stewart Williams
BACKGROUND: Globally people are living longer and enduring non-communicable diseases (NCDs) many of which co-occur as multimorbidity. Demographic and socioeconomic factors are determinants of inequalities and inequities in health. There is a need for country-specific evidence of NCD inequalities in developing countries where populations are ageing rapidly amid economic and social change. The study measures and decomposes socioeconomic inequality in single and multiple NCD morbidity in adults aged 50 and over in China and Ghana...
May 15, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28499387/evolution-of-the-fourth-stage-of-epidemiologic-transition-in-people-aged-80%C3%A2-years-and-over-population-based-cohort-study-using-electronic-health-records
#14
Nisha C Hazra, Martin Gulliford
BACKGROUND: In the "fourth stage" of epidemiological transition, the distribution of non-communicable diseases is expected to shift to more advanced ages, but age-specific changes beyond 80 years of age have not been reported. METHODS: This study aimed to evaluate demographic and health transitions in a population aged 80 years and over in the United Kingdom from 1990 to 2014, using primary care electronic health records. Epidemiological analysis of chronic morbidities and age-related impairments included a cohort of 299,495 participants, with stratified sampling by five-year age group up to 100 years and over...
May 12, 2017: Population Health Metrics
https://www.readbyqxmd.com/read/28474459/use-of-guideline-recommended-adjuvant-therapies-and-survival-outcomes-for-people-with-colorectal-cancer-at-tertiary-referral-hospitals-in-south-australia
#15
Pamela Adelson, Kellie Fusco, Christos Karapetis, David Wattchow, Rohit Joshi, Timothy Price, Greg Sharplin, David Roder
RATIONALE, AIMS AND OBJECTIVES: Adjuvant care for colorectal cancer (CRC) has increased over the past 3 decades in South Australia (SA) in accordance with national treatment guidelines. This study explores the (1) receipt of adjuvant therapy for CRC in SA as related to national guideline recommendations, with a focus on stage C colon and stage B and C rectal cancer; (2) timing of these adjuvant therapies in relation to surgery; and (3) comparative survival outcomes. METHODS: Data from the SA Clinical Cancer Registry from 4 tertiary referral hospitals for 2000 to 2010 were examined...
May 4, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28390184/outcomes-in-older-adults-with-multimorbidity-associated-with-predominant-provider-of-care-specialty
#16
Julie P W Bynum, Chiang-Hua Chang, Andrea Austin, Don Carmichael, Ellen Meara
OBJECTIVES: To determine whether receiving the predominance of ambulatory visits from a primary care provider compared to a specialty provider is associated with better outcomes in older adults with multi morbidity. DESIGN: Observational study using propensity score matching. SETTING: Medicare fee-for-service, 2011-12. PARTICIPANTS: Beneficiaries aged 65 and older with multimorbidity. MEASUREMENTS: The independent variable was an indicator for having a specialty (versus primary care) as the predominant provider of care (PPC)...
September 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28296975/socioeconomic-inequalities-in-health-in-the-context-of-multimorbidity-a-korean-panel-study
#17
Myung Ki, Yo Han Lee, Yong-Soo Kim, Ji-Yeon Shin, Jiseun Lim, James Nazroo
Socioeconomic inequalities in health are commonly known to decrease at late age. Yet, it remains unclear whether socioeconomic inequalities in health at late age appear in relation to multimorbidity, particularly in Korea where social support remains unsatisfactory for older people. Using three waves of Korea Health Panel, data of 19,942 observations with repeated measure were constructed to ensure a temporal sequence between three socioeconomic measures (i.e., poverty, employment status, and education) and multimorbidity with a t to t+1 year transition...
2017: PloS One
https://www.readbyqxmd.com/read/28273230/effects-of-air-pollution-caused-by-sugarcane-burning-in-western-s%C3%A3-o-paulo-on-the-cardiovascular-system
#18
Paula Roberta da Silva Pestana, Alfésio Luís Ferreira Braga, Ercy Mara Cipulo Ramos, Ariadna Ferraz de Oliveira, Christian Robert Osadnik, Aline Duarte Ferreira, Dionei Ramos
OBJECTIVE: To evaluate the effects of acute exposure to air pollutants (NO2 and PM10) on hospitalization of adults and older people with cardiovascular diseases in Western São Paulo. METHODS: Daily cardiovascular-related hospitalization data (CID10 - I00 to I99) were acquired by the Department of Informatics of the Brazilian Unified Health System (DATASUS) from January 2009 to December 2012. Daily levels of NO2 and PM10 and weather data were obtained from Companhia Ambiental do Estado de São Paulo (CETESB - São Paulo State Environmental Agency)...
March 2, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/27648920/insulin-like-growth-factor-1-and-risk-of-depression-in-older-people-the-english-longitudinal-study-of-ageing
#19
S Chigogora, P Zaninotto, M Kivimaki, A Steptoe, G D Batty
Depressive disorders are a leading cause of disability in older age. Although the role of psychosocial and behavioural predictors has been well examined, little is known about the biological origins of depression. Findings from animal studies have implicated insulin-like growth factor 1 (IGF-1) in the aetiology of this disorder. A total of 6017 older adults (mean age of 65.7 years; 55% women) from the English Longitudinal Study of Ageing provided serum levels of IGF-1 (mean=15.9 nmol l(-1), s.d. 5.7) during a nurse visit in 2008...
September 20, 2016: Translational Psychiatry
https://www.readbyqxmd.com/read/27595357/adult-cancers-in-adolescents-and-young-adults
#20
REVIEW
Valérie Laurence, Maria Marples, Daniel P Stark
The pattern of cancer seen in young people changes with increasing age, transitioning from childhood- to adult-type cancer in adolescence and the third decade. The risk factors, presentation and biology of cancer in young adults differ from those in the older adult population. Factors of particular significance in adolescents and young adults (AYAs) include genetic predisposition to adult-type cancer, diagnostic uncertainty, long-term morbidity and considerations of fertility. New systemic therapies are being introduced that can prolong life and even increase the chance of cure, but the impact on AYAs is uncertain, as these patients are often under-represented in clinical trials...
2016: Progress in Tumor Research
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