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patterns of multimorbidity

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https://www.readbyqxmd.com/read/28622764/-in-the-mood-for-ageing-determinants-of-subjective-well-being-in-older-men-and-women-of-the-population-based-kora-age-study
#1
Karoline Lukaschek, Anushiya Vanajan, Hamimatunnisa Johar, Nina Weiland, Karl-Heinz Ladwig
BACKGROUND: To investigate risk factors associated with low subjective well-being (SWB) in men and women (≥65 years) separately with a special focus on emotional distress. METHODS: A cross-sectional analysis was conducted among 3602 participants (50.6% women) aged 65-90 years (mean age 72.8 years, SD ± 5.8) from the population-based KORA-Age study conducted in 2008/2009. SWB was assessed using the WHO-5 well-being index (score range: 0 to 100). SWB was dichotomized into "low" (score ≤ 50) and "high" (score > 50) SWB...
June 16, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28622657/patterns-of-multimorbidity-in-people-with-severe-or-profound-intellectual-and-motor-disabilities
#2
E A van Timmeren, A Waninge, H M J van Schrojenstein Lantman-de, A A J van der Putten, C P van der Schans
BACKGROUND: People with severe or profound intellectual and motor disabilities (SPIMD) experience multimorbidity and have complex health needs. Multimorbidity increases mortality, decreases functioning, and negatively influences quality of life. Information regarding patterns of multimorbidity in people with SPIMD may lead to proactive prevention, specifically detection and treatment of physical health problems at an early stage and prevention of secondary complications. AIM: The aim of this study was to explore patterns of multimorbidity in individuals with SPIMD...
June 13, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28601836/contextual-and-individual-inequalities-of-multimorbidity-in-brazilian-adults-a-cross-sectional-national-based-study
#3
Bruno P Nunes, Alexandre D P Chiavegatto Filho, Sanghamitra Pati, Doralice S Cruz Teixeira, Thaynã R Flores, Fabio A Camargo-Figuera, Tiago N Munhoz, Elaine Thumé, Luiz A Facchini, Sandro R Rodrigues Batista
OBJECTIVES: The study aims to evaluate the magnitude of multimorbidity in Brazilian adults, as well to measure their association with individual and contextual factors stratified by Brazilian states and regions. METHODS: A national-based cross-sectional study was carried out in 2013 with Brazilian adults. Multimorbidity was evaluated by a list of 22 physical and mental morbidities (based on self-reported medical diagnosis and Patient Health Questionnaire-9 for depression)...
June 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28577866/multimorbidity-patterns-in-older-adults-an-approach-to-the-complex-interrelationships-among-chronic-diseases
#4
Dolores Mino-León, Hortensia Reyes-Morales, Svetlana V Doubova, Ricardo Pérez-Cuevas, Liliana Giraldo-Rodríguez, Marcela Agudelo-Botero
BACKGROUND AND AIMS: There is a growing need for evidence based answers to multimorbidity, especially in primary care settings. The aim was estimate the prevalence and patterns of multimorbidity in a Mexican population of public health institution users ≥60 years old. METHODS: Observational and multicenter study was carried out in four family medicine units in Mexico City; included older men and women who attended at least one consultation with their family doctor during 2013...
January 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/28570109/management-of-long-term-conditions-and-dementia-the-role-of-the-admiral-nurse
#5
Cathy Knight, Karen Harrison Dening
As life expectancy increases so people often develop a range of conditions and disabilities in the years before death. Multimorbidity represents the most common 'disease pattern' found among the elderly and is characterised by complex interactions of co-existing diseases where a medical approach focused on a single disease does not suffice. People with dementia who also have other comorbidities do not always have their comorbid conditions managed as those without dementia which often lead to a high number of hospital admissions with longer lengths of stay and greater treatment costs...
June 2, 2017: British Journal of Community Nursing
https://www.readbyqxmd.com/read/28569290/novel-combined-management-approaches-to-patients-with-diabetes-chronic-kidney-disease-and-cardiovascular-disease
#6
J Spaak
Most patients we care for today suffer from more than one chronic disease, and multimorbidity is a rapidly growing challenge. Concomitant cardiovascular disease, renal dysfunction and diabetes represent a large proportion of all patients in cardiology, nephrology and diabetology. These entities commonly overlap due to their negative effects on vascular function and an accelerated atherosclerosis progression. At the same time, a progressive subspecialisation has caused the cardiologist to treat 'only' the heart, nephrologists 'only' the kidneys and endocrinologists' 'only' diabetes...
March 2017: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/28506233/measurement-and-decomposition-of-socioeconomic-inequality-in-single-and-multimorbidity-in-older-adults-in-china-and-ghana-results-from-the-who-study-on-global-ageing-and-adult-health-sage
#7
Rasha Kunna, Miguel San Sebastian, Jennifer Stewart Williams
BACKGROUND: Globally people are living longer and enduring non-communicable diseases (NCDs) many of which co-occur as multimorbidity. Demographic and socioeconomic factors are determinants of inequalities and inequities in health. There is a need for country-specific evidence of NCD inequalities in developing countries where populations are ageing rapidly amid economic and social change. The study measures and decomposes socioeconomic inequality in single and multiple NCD morbidity in adults aged 50 and over in China and Ghana...
May 15, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28486983/social-disparities-in-the-prevalence-of-multimorbidity-a-register-based-population-study
#8
Michaela L Schiøtz, Anders Stockmarr, Dorte Høst, Charlotte Glümer, Anne Frølich
BACKGROUND: Prevalences of multimorbidity vary between European studies and several methods and definitions are used. In this study we examine the prevalence of multimorbidity in relation to age, gender and educational attainment and the association between physical and mental health conditions and educational attainment in a Danish population. METHODS: A cross-sectional design was used to study the prevalence of multimorbidity, defined as two or more chronic conditions, and of comorbid physical and mental health conditions across age groups and educational attainment levels among 1,397,173 individuals aged 16 years and older who lived in the Capital Region of Denmark on January 1st, 2012...
May 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28449592/-i-had-to-change-so-much-in-my-life-to-live-with-my-new-limitations-multimorbid-patients-descriptions-of-their-most-bothersome-chronic-conditions
#9
Cindie A Slightam, Kirsten Brandt, Emily C Jenchura, Eleanor T Lewis, Steven M Asch, Donna M Zulman
Objective To characterize diseases that are described as most bothersome by individuals with multiple chronic conditions and to identify themes that characterize their experiences with their most bothersome condition. Methods In a survey of patients at an academic center and a Veterans Affairs hospital, we asked individuals with multiple chronic conditions to identify their most bothersome chronic condition and describe why it is challenging. Standard content analysis methods were used to code responses and identify themes reflecting characteristics of most bothersome conditions...
January 1, 2017: Chronic Illness
https://www.readbyqxmd.com/read/28390184/outcomes-in-older-adults-with-multimorbidity-associated-with-predominant-provider-of-care-specialty
#10
Julie P W Bynum, Chiang-Hua Chang, Andrea Austin, Don Carmichael, Ellen Meara
OBJECTIVES: To determine whether receiving the predominance of ambulatory visits from a primary care provider compared to a specialty provider is associated with better outcomes in older adults with multi morbidity. DESIGN: Observational study using propensity score matching. SETTING: Medicare fee-for-service, 2011-12. PARTICIPANTS: Beneficiaries aged 65 and older with multimorbidity. MEASUREMENTS: The independent variable was an indicator for having a specialty (versus primary care) as the predominant provider of care (PPC)...
April 8, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28383714/a-systems-approach-identifies-time-dependent-associations-of-multimorbidities-with-pancreatic-cancer-risk
#11
P Gomez-Rubio, V Rosato, M Marquez, C Bosetti, E Molina-Montes, M Rava, J Piñero, C W Michalski, A Farré, X Molero, M Löhr, L Ilzarbe, J Perea, W Greenhalf, M O'Rorke, A Tardón, T Gress, V M Barberà, T Crnogorac-Jurcevic, L Muñoz-Bellvís, E Domínguez-Muñoz, A Gutiérrez-Sacristán, J Balsells, E Costello, C Guillén-Ponce, J Huang, M Iglesias, J Kleeff, B Kong, J Mora, L Murray, D O'Driscoll, P Peláez, I Poves, R T Lawlor, A Carrato, M Hidalgo, A Scarpa, L Sharp, L I Furlong, F X Real, C La Vecchia, N Malats
Background: HASH(0x4375f10) Pancreatic ductal adenocarcinoma (PDAC) is usually diagnosed in late adulthood; therefore, many patients suffer or have suffered from other diseases. Identifying disease-patterns associated with PDAC risk may enable a better characterization of high-risk patients. Methods: HASH(0x3379520) Multimorbidity patterns (MPs) were assessed from 17 self-reported conditions using hierarchical clustering, principal component, and factor analyses in 1705 PDAC cases and 1084 controls from a European population...
April 5, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28296975/socioeconomic-inequalities-in-health-in-the-context-of-multimorbidity-a-korean-panel-study
#12
Myung Ki, Yo Han Lee, Yong-Soo Kim, Ji-Yeon Shin, Jiseun Lim, James Nazroo
Socioeconomic inequalities in health are commonly known to decrease at late age. Yet, it remains unclear whether socioeconomic inequalities in health at late age appear in relation to multimorbidity, particularly in Korea where social support remains unsatisfactory for older people. Using three waves of Korea Health Panel, data of 19,942 observations with repeated measure were constructed to ensure a temporal sequence between three socioeconomic measures (i.e., poverty, employment status, and education) and multimorbidity with a t to t+1 year transition...
2017: PloS One
https://www.readbyqxmd.com/read/28274966/pattern-correlates-and-implications-of-non-communicable-disease-multimorbidity-among-older-adults-in-selected-indian-states-a-cross-sectional-study
#13
G K Mini, K R Thankappan
OBJECTIVES: The objective of the present study was to estimate the proportion of older adults with non-communicable disease (NCD) multimorbidity, its correlates and implications in selected Indian states. METHODS: The study used data of 9852 older adults (≥60 years) (men 47%, mean age 68 years) collected by the United Nations Population Fund from seven selected Indian states. Multiple logistic regression analysis was used to assess the correlates of NCD multimorbidity and hospitalisation...
March 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28253982/clinical-aspects-of-glucose-metabolism-and-chronic-disease
#14
J W Culberson
The burden of chronic disease is an emerging world health problem. Advances made in the treatment of individual disease states often fail to consider multimorbidity patterns in clinical research models. Adjusting for age as a confounder ignores its contribution as a powerful risk factor for most chronic diseases. Sarcopenia is an age-related loss of skeletal muscle mass, which is accelerated by chronic inflammation and its resulting cascade of cytokines. Skeletal muscle loss results in insulin resistance, hyperglycemia, and altered mitochondrial glucose signaling pathways...
2017: Progress in Molecular Biology and Translational Science
https://www.readbyqxmd.com/read/28236637/the-sensitization-pattern-differs-according-to-rhinitis-and-asthma-multimorbidity-in-adults-the-egea-study
#15
E Burte, J Bousquet, V Siroux, J Just, B Jacquemin, R Nadif
BACKGROUND: Mono- and polysensitization are different IgE-mediated allergic phenotypes in children. Allergic sensitization is associated with both allergic asthma and allergic rhinitis, however, associations between the sensitization pattern and particularly polysensitization with asthma and rhinitis remains poorly studied in adults. AIM: The aim of this study was to assess how the allergic sensitization pattern associates with asthma, rhinitis and their multimorbidity...
April 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28184153/multimorbidity-as-specific-disease-combinations-an-important-predictor-factor-for-mortality-in-octogenarians-the-octabaix-study
#16
Assumpta Ferrer, Francesc Formiga, Héctor Sanz, Jesús Almeda, Glòria Padrós
BACKGROUND: The population is aging and multimorbidity is becoming a common problem in the elderly. OBJECTIVE: To explore the effect of multimorbidity patterns on mortality for all causes at 3- and 5-year follow-up periods. MATERIALS AND METHODS: A prospective community-based cohort (2009-2014) embedded within a randomized clinical trial was conducted in seven primary health care centers, including 328 subjects aged 85 years at baseline. Sociodemographic variables, sensory status, cardiovascular risk factors, comorbidity, and geriatric tests were analyzed...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28182778/epidemiology-of-multimorbidity-within-the-brazilian-adult-general-population-evidence-from-the-2013-national-health-survey-pns-2013
#17
Magdalena Rzewuska, João Mazzoncini de Azevedo-Marques, Domenica Coxon, Maria Lúcia Zanetti, Ana Carolina Guidorizzi Zanetti, Laercio Joel Franco, Jair Lício Ferreira Santos
Middle-income countries are facing a growing challenge of adequate health care provision for people with multimorbidity. The objectives of this study were to explore the distribution of multimorbidity and to identify patterns of multimorbidity in the Brazilian general adult population. Data from 60202 adults, aged ≥18 years that completed the individual questionnaire of the National Health Survey 2013 (Portuguese: "Pesquisa Nacional de Saúde"-"PNS") was used. We defined multimorbidity as the presence of two or more chronic conditions, including self-reported diagnoses and responses to the 9-item Patient Health Questionnaire for depression...
2017: PloS One
https://www.readbyqxmd.com/read/28107252/multimorbidity-and-the-risk-of-all-cause-30-day-readmission-in-the-setting-of-multidisciplinary-management-of-chronic-heart-failure-a-retrospective-analysis-of-830-hospitalized-patients-in-australia
#18
Joshua F Wiley, Yih-Kai Chan, Yasmin Ahamed, Jocasta Ball, Melinda J Carrington, Barbara Riegel, Simon Stewart
BACKGROUND: Multimorbidity has an adverse effect on health outcomes in hospitalized individuals with chronic heart failure (CHF), but the modulating effect of multidisciplinary management is unknown. OBJECTIVE: The aim of this study was to test the hypothesis that increasing morbidity would independently predict an increasing risk of 30-day readmission despite multidisciplinary management of CHF. METHODS: We studied patients hospitalized for any reason with heart failure receiving nurse-led, postdischarge multidisciplinary management...
January 20, 2017: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28056050/a-latent-class-analysis-of-multimorbidity-and-the-relationship-to-socio-demographic-factors-and-health-related-quality-of-life-a-national-population-based-study-of-162-283-danish-adults
#19
Finn Breinholt Larsen, Marie Hauge Pedersen, Karina Friis, Charlotte Glümer, Mathias Lasgaard
OBJECTIVES: To identify patterns of multimorbidity in the general population and examine how these patterns are related to socio-demographic factors and health-related quality of life. STUDY DESIGN AND SETTING: We used latent class analysis to identify subgroups with statistically distinct and clinically meaningful disease patterns in a nationally representative sample of Danish adults (N = 162,283) aged 16+ years. The analysis was based on 15 chronic diseases. RESULTS: Seven classes with different disease patterns were identified: a class with no or only a single chronic condition (59% of the population) labeled "1) Relatively Healthy" and six classes with a very high prevalence of multimorbidity labeled; "2) Hypertension" (14%); "3) Musculoskeletal Disorders" (10%); "4) Headache-Mental Disorders" (7%); "5) Asthma-Allergy" (6%); "6) Complex Cardiometabolic Disorders" (3%); and "7) Complex Respiratory Disorders" (2%)...
2017: PloS One
https://www.readbyqxmd.com/read/28029586/social-determinants-multimorbidity-and-patterns-of-end-of-life-care-in-older-adults-dying-from-cancer
#20
Siran M Koroukian, Nicholas K Schiltz, David F Warner, Charles W Given, Mark Schluchter, Cynthia Owusu, Nathan A Berger
OBJECTIVE: Most prior studies on aggressive end-of-life care in older patients with cancer have accounted for social determinants of health (e.g., race, income, and education), but rarely for multimoribidity (MM). In this study, we examine the association between end-of-life care and each of the social determinants of health and MM, hypothesizing that higher MM is associated with less aggressive care. METHODS: From the linked 1991-2008 Health and Retirement Study, Medicare data, and the National Death Index, we identified fee-for-service patients age ≥66years who died from cancer (n=835)...
March 2017: Journal of Geriatric Oncology
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