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https://www.readbyqxmd.com/read/28931931/screening-of-obstructive-sleep-apnea-syndrome-by-electronic-nose-analysis-of-volatile-organic-compounds
#1
Simone Scarlata, Giorgio Pennazza, Marco Santonico, Simona Santangelo, Isaura Rossi Bartoli, Chiara Rivera, Chiara Vernile, Antonio De Vincentis, Raffaele Antonelli Incalzi
Obstructive Sleep Apnea Syndrome (OSAS) carries important social and economic implications. Once the suspicion of OSAS has arisen, Polysomnography (PSG) represents the diagnostic gold standard. However, about 45% of people who have undergone PSG are free from OSAS. Thus, efforts should be made to improve the selection of subjects. We verified whether the pattern of Volatile Organic Compounds (VOCs) helps to select patients amenable to PSG. We studied 136 subjects (20 obese non-OSAS, 20 hypoxic OSAS, 20 non-hypoxic OSAS, and 20 non-hypoxic Chronic Obstructive Pulmonary Disease (COPD) vs 56 healthy controls) without any criteria of exclusion for comorbidity to deal with a real-life population...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28922277/percutaneous-posterior-trans-articular-atlantoaxial-fixation-for-the-treatment-of-odontoid-fractures-in-the-elderly-a-prospective-study
#2
Mohamed Alhashash, Mootaz Shousha, Hany Gendy, Ahmed Samir Barakat, Heinrich Boehm
STUDY DESIGN: A prospective study of 20 multimorbid patients older than 65 years undergoing minimally invasive surgical treatment for odontoid fracture. OBJECTIVES: To analyze the results of percutaneous transarticular atlantoaxial screw fixation as a new minimally invasive treatment modality in this high risk group of patients. SUMMARY OF BACKGROUND DATA: Odontoid fractures are a common injury pattern in the elderly. These fractures typically present significant challenges as geriatric patients often have multiple comorbidities that may adversely affect fracture management...
September 15, 2017: Spine
https://www.readbyqxmd.com/read/28910309/pattern-and-severity-of-multimorbidity-among-patients-attending-primary-care-settings-in-odisha-india
#3
RANDOMIZED CONTROLLED TRIAL
Sanghamitra Pati, Subhashisa Swain, Job Metsemakers, J André Knottnerus, Marjan van den Akker
Multimorbidity is increasingly the primary concern of healthcare systems globally with substantial implications for patient outcomes and resource cost. A critical knowledge gap exists as to the magnitude of multimorbidity in primary care practice in low and middle income countries with available information limited to prevalence. In India, primary care forms the bulk of the health care delivery being provided through both public (community health center) and private general practice setting. We undertook a study to identify multimorbidity patterns and relate these patterns to severity among primary care attendees in Odisha state of India...
2017: PloS One
https://www.readbyqxmd.com/read/28878150/multimorbidity-in-chronic-conditions-public-primary-care-patients-in-four-greater-mekong-countries
#4
Supa Pengpid, Karl Peltzer
The aim of this study was to explore the prevalence, pattern, and social determinants of chronic conditions multimorbidity among chronic disease primary care patients in four Greater Mekong countries (Cambodia, Myanmar, Thailand, and Vietnam). In a cross-sectional survey, chronic disease patients accessing primary care were recruited if they had been diagnosed with any of 21 chronic conditions in the past 12 months, and were interviewed with a structured questionnaire on anxiety, depression, alcohol use, tobacco use, dietary behaviour, physical activity, and quality of life...
September 6, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28835246/the-contribution-of-risk-factors-to-socioeconomic-inequalities-in-multimorbidity-across-the-lifecourse-a-longitudinal-analysis-of-the-twenty-07-cohort
#5
Srinivasa Vittal Katikireddi, Kathryn Skivington, Alastair H Leyland, Kate Hunt, Stewart W Mercer
BACKGROUND: Multimorbidity is a major challenge to health systems globally and disproportionately affects socioeconomically disadvantaged populations. We examined socioeconomic inequalities in developing multimorbidity across the lifecourse and investigated the contribution of five behaviour-related risk factors. METHODS: The Twenty-07 study recruited participants aged approximately 15, 35, and 55 years in 1987 and followed them up over 20 years. The primary outcome was development of multimorbidity (2+ health conditions)...
August 24, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28821233/latent-class-analysis-of-multimorbidity-patterns-and-associated-outcomes-in-spanish-older-adults-a-prospective-cohort-study
#6
Beatriz Olaya, Maria Victoria Moneta, Francisco Félix Caballero, Stefanos Tyrovolas, Ivet Bayes, José Luis Ayuso-Mateos, Josep Maria Haro
BACKGROUND: This study sought to identify multimorbidity patterns and determine the association between these latent classes with several outcomes, including health, functioning, disability, quality of life and use of services, at baseline and after 3 years of follow-up. METHODS: We analyzed data from a representative Spanish cohort of 3541 non-institutionalized people aged 50 years old and over. Measures were taken at baseline and after 3 years of follow-up. Latent Class Analysis (LCA) was conducted using eleven common chronic conditions...
August 18, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28772096/prospective-identification-of-patients-at-risk-for-unwarranted-variation-in-treatment
#7
Amy S Kelley, Evan Bollens-Lund, Kenneth E Covinsky, Jonathan S Skinner, R Sean Morrison
BACKGROUND: Understanding factors associated with treatment intensity may help ensure higher value healthcare. OBJECTIVE: To investigate factors associated with Medicare costs among prospectively identified, seriously ill older adults and examine if baseline prognosis influences the impact of these factors. DESIGN/SUBJECTS: Prospective observation of Health and Retirement Study cohort with linked Medicare claims. MEASUREMENTS: We identified people with incident serious illness (a serious medical condition, for example, metastatic cancer or functional impairment); calculated subjects' one-year mortality risk; and then followed them for one year...
August 3, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28764205/prevalence-and-patterns-of-multimorbidity-among-human-immunodeficiency-virus-positive-people-in-odisha-india-an-exploratory-study
#8
Sanghamitra Pati, Shreeporna Bhattacharya, Subhashisa Swain
INTRODUCTION: Improved and efficient Anti-Retroviral Therapy (ART) has turned HIV positive into a chronic disorder. The increase in life expectancy and quality of life comes with an increased risk of multimorbidity from the traditional risk factors. AIM: To explore the prevalence of multimorbidity among People Living with HIV (PLHIV). MATERIALS AND METHODS: An exploratory cross-sectional study was carried out in an ART center of Odisha, India, from November 2013 to December 2013...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28709115/development-and-validation-of-the-korea-dementia-comorbidity-index-kdci-a-nationwide-population-based-cohort-study-from-2002-to-2013
#9
Jae-Hyun Kim, Ki-Bong Yoo, Yunhwan Lee
This study develop and validate a simple and accessible measure of comorbidity, named the Korean Dementia Comorbidity index (KDCI), to assist in predicting the onset of dementia. This study used the National Health Insurance Service-Cohort Sample Database from 2002 to 2013 (n=23,856). Cox proportional hazard model was used to estimate incident dementia (International Classification of Disease, 10th edition (ICD-10) codes: F00-F03, G30, G311), with a hazard ratio higher than 1.05 for each comorbid condition being assigned a score...
September 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28702837/-compression-or-expansion-of-morbidity-in-outpatient-healthcare-generation-65plus-in-2007-and-2014
#10
Janina Frank, Birgit Babitsch
BACKGROUND: The ageing population raises the question whether there is a compression or expansion of morbidity. OBJECTIVE: This study examined the development of morbidity and the associated outpatient volume of services in outpatient healthcare. MATERIAL AND METHODS: With a nationwide sample of statutory health insurance patients, the development of the documented morbidity and outpatient volume of services of the generation 65plus was empirically examined by a retrospective, cohort-specific study based on outpatient claims data covering the years 2007 and 2014...
July 12, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28692013/multimorbidity-and-health-care-service-utilization-in-the-australian-workforce-findings-from-the-national-health-survey
#11
Lili Wang, Andrew J Palmer, Petr Otahal, Fiona Cocker, Kristy Sanderson
OBJECTIVES: The aim of this study was to understand the patterns of health care service utilization in employees with multimorbidity. METHODS: Data were obtained from the 2011 to 2012 cross-sectional Australian National Health Survey. Past-month health care service utilization was collected for each chronic condition from a pre-specified list. Descriptive, logistic, and Poisson regression analyses were used. The data were weighted to produce nationally representative estimates...
August 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28679803/epidemiology-and-patterns-of-care-at-the-end-of-life-rising-complexity-shifts-in-care-patterns-and-sites-of-death
#12
Melissa D Aldridge, Elizabeth H Bradley
In 2015 an estimated 2.7 million people in the United States (1 percent of the population) died. Although decedents' illness experience varies substantially, important trends in care at the end of life are evident. To identify the most pressing health care policy issues related to end-of-life care, we present a comprehensive picture of the epidemiology and care patterns of people in the last stage of life. We identify three key trends in end-of-life care: increasing diversity in the primary diagnoses of decedents, increases in multimorbidity and illness complexity among people with terminal illnesses, and shifts in patterns of care at the end of life and in sites of death...
July 1, 2017: Health Affairs
https://www.readbyqxmd.com/read/28674127/multimorbidity-and-patterns-of-chronic-conditions-in-a-primary-care-population-in-switzerland-a-cross-sectional-study
#13
Anouk Déruaz-Luyet, A Alexandra N'Goran, Nicolas Senn, Patrick Bodenmann, Jérôme Pasquier, Daniel Widmer, Ryan Tandjung, Thomas Rosemann, Peter Frey, Sven Streit, Andreas Zeller, Dagmar M Haller, Sophie Excoffier, Bernard Burnand, Lilli Herzig
OBJECTIVE: To characterise in details a random sample of multimorbid patients in Switzerland and to evaluate the clustering of chronic conditions in that sample. METHODS: 100 general practitioners (GPs) each enrolled 10 randomly selected multimorbid patients aged ≥18 years old and suffering from at least three chronic conditions. The prevalence of 75 separate chronic conditions from the International Classification of Primary Care-2 (ICPC-2) was evaluated in these patients...
July 2, 2017: BMJ Open
https://www.readbyqxmd.com/read/28645968/development-of-a-meta-algorithm-for-guiding-primary-care-encounters-for-patients-with-multimorbidity-using-evidence-based-and-case-based-guideline-development-methodology
#14
Cathleen Muche-Borowski, Dagmar Lühmann, Ingmar Schäfer, Rebekka Mundt, Hans-Otto Wagner, Martin Scherer
OBJECTIVE: The study aimed to develop a comprehensive algorithm (meta-algorithm) for primary care encounters of patients with multimorbidity. We used a novel, case-based and evidence-based procedure to overcome methodological difficulties in guideline development for patients with complex care needs. STUDY DESIGN: Systematic guideline development methodology including systematic evidence retrieval (guideline synopses), expert opinions and informal and formal consensus procedures...
June 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/28644851/comorbidities-in-the-diseasome-are-more-apparent-than-real-what-bayesian-filtering-reveals-about-the-comorbidities-of-depression
#15
Peter Marx, Peter Antal, Bence Bolgar, Gyorgy Bagdy, Bill Deakin, Gabriella Juhasz
Comorbidity patterns have become a major source of information to explore shared mechanisms of pathogenesis between disorders. In hypothesis-free exploration of comorbid conditions, disease-disease networks are usually identified by pairwise methods. However, interpretation of the results is hindered by several confounders. In particular a very large number of pairwise associations can arise indirectly through other comorbidity associations and they increase exponentially with the increasing breadth of the investigated diseases...
June 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28622764/-in-the-mood-for-ageing-determinants-of-subjective-well-being-in-older-men-and-women-of-the-population-based-kora-age-study
#16
Karoline Lukaschek, Anushiya Vanajan, Hamimatunnisa Johar, Nina Weiland, Karl-Heinz Ladwig
BACKGROUND: To investigate risk factors associated with low subjective well-being (SWB) in men and women (≥65 years) separately with a special focus on emotional distress. METHODS: A cross-sectional analysis was conducted among 3602 participants (50.6% women) aged 65-90 years (mean age 72.8 years, SD ± 5.8) from the population-based KORA-Age study conducted in 2008/2009. SWB was assessed using the WHO-5 well-being index (score range: 0 to 100). SWB was dichotomized into "low" (score ≤ 50) and "high" (score > 50) SWB...
June 16, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28622657/patterns-of-multimorbidity-in-people-with-severe-or-profound-intellectual-and-motor-disabilities
#17
E A van Timmeren, A Waninge, H M J van Schrojenstein Lantman-de, A A J van der Putten, C P van der Schans
BACKGROUND: People with severe or profound intellectual and motor disabilities (SPIMD) experience multimorbidity and have complex health needs. Multimorbidity increases mortality, decreases functioning, and negatively influences quality of life. Information regarding patterns of multimorbidity in people with SPIMD may lead to proactive prevention, specifically detection and treatment of physical health problems at an early stage and prevention of secondary complications. AIM: The aim of this study was to explore patterns of multimorbidity in individuals with SPIMD...
August 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28601836/contextual-and-individual-inequalities-of-multimorbidity-in-brazilian-adults-a-cross-sectional-national-based-study
#18
Bruno P Nunes, Alexandre D P Chiavegatto Filho, Sanghamitra Pati, Doralice S Cruz Teixeira, Thaynã R Flores, Fabio A Camargo-Figuera, Tiago N Munhoz, Elaine Thumé, Luiz A Facchini, Sandro R Rodrigues Batista
OBJECTIVES: The study aims to evaluate the magnitude of multimorbidity in Brazilian adults, as well to measure their association with individual and contextual factors stratified by Brazilian states and regions. METHODS: A national-based cross-sectional study was carried out in 2013 with Brazilian adults. Multimorbidity was evaluated by a list of 22 physical and mental morbidities (based on self-reported medical diagnosis and Patient Health Questionnaire-9 for depression)...
June 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28577866/multimorbidity-patterns-in-older-adults-an-approach-to-the-complex-interrelationships-among-chronic-diseases
#19
Dolores Mino-León, Hortensia Reyes-Morales, Svetlana V Doubova, Ricardo Pérez-Cuevas, Liliana Giraldo-Rodríguez, Marcela Agudelo-Botero
BACKGROUND AND AIMS: There is a growing need for evidence based answers to multimorbidity, especially in primary care settings. The aim was estimate the prevalence and patterns of multimorbidity in a Mexican population of public health institution users ≥60 years old. METHODS: Observational and multicenter study was carried out in four family medicine units in Mexico City; included older men and women who attended at least one consultation with their family doctor during 2013...
January 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/28570109/management-of-long-term-conditions-and-dementia-the-role-of-the-admiral-nurse
#20
Cathy Knight, Karen Harrison Dening
As life expectancy increases so people often develop a range of conditions and disabilities in the years before death. Multimorbidity represents the most common 'disease pattern' found among the elderly and is characterised by complex interactions of co-existing diseases where a medical approach focused on a single disease does not suffice. People with dementia who also have other comorbidities do not always have their comorbid conditions managed as those without dementia which often lead to a high number of hospital admissions with longer lengths of stay and greater treatment costs...
June 2, 2017: British Journal of Community Nursing
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