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patterns of multimorbidity

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https://www.readbyqxmd.com/read/28296975/socioeconomic-inequalities-in-health-in-the-context-of-multimorbidity-a-korean-panel-study
#1
Myung Ki, Yo Han Lee, Yong-Soo Kim, Ji-Yeon Shin, Jiseun Lim, James Nazroo
Socioeconomic inequalities in health are commonly known to decrease at late age. Yet, it remains unclear whether socioeconomic inequalities in health at late age appear in relation to multimorbidity, particularly in Korea where social support remains unsatisfactory for older people. Using three waves of Korea Health Panel, data of 19,942 observations with repeated measure were constructed to ensure a temporal sequence between three socioeconomic measures (i.e., poverty, employment status, and education) and multimorbidity with a t to t+1 year transition...
2017: PloS One
https://www.readbyqxmd.com/read/28274966/pattern-correlates-and-implications-of-non-communicable-disease-multimorbidity-among-older-adults-in-selected-indian-states-a-cross-sectional-study
#2
G K Mini, K R Thankappan
OBJECTIVES: The objective of the present study was to estimate the proportion of older adults with non-communicable disease (NCD) multimorbidity, its correlates and implications in selected Indian states. METHODS: The study used data of 9852 older adults (≥60 years) (men 47%, mean age 68 years) collected by the United Nations Population Fund from seven selected Indian states. Multiple logistic regression analysis was used to assess the correlates of NCD multimorbidity and hospitalisation...
March 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28253982/clinical-aspects-of-glucose-metabolism-and-chronic-disease
#3
J W Culberson
The burden of chronic disease is an emerging world health problem. Advances made in the treatment of individual disease states often fail to consider multimorbidity patterns in clinical research models. Adjusting for age as a confounder ignores its contribution as a powerful risk factor for most chronic diseases. Sarcopenia is an age-related loss of skeletal muscle mass, which is accelerated by chronic inflammation and its resulting cascade of cytokines. Skeletal muscle loss results in insulin resistance, hyperglycemia, and altered mitochondrial glucose signaling pathways...
2017: Progress in Molecular Biology and Translational Science
https://www.readbyqxmd.com/read/28236637/the-sensitization-pattern-differs-according-to-rhinitis-and-asthma-multimorbidity-in-adults-the-egea-study
#4
Emilie Burte, Jean Bousquet, Valérie Siroux, Jocelyne Just, Bénédicte Jacquemin, Rachel Nadif
BACKGROUND: Mono- and polysensitization are different IgE-mediated allergic phenotypes in children. Allergic sensitization is associated with both allergic asthma and allergic rhinitis, however, associations between the sensitization pattern and particularly polysensitization with asthma and rhinitis remains poorly studied in adults. AIM: The aim of this study was to assess how the allergic sensitization pattern associates with asthma, rhinitis and their multimorbidity...
February 25, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28184153/multimorbidity-as-specific-disease-combinations-an-important-predictor-factor-for-mortality-in-octogenarians-the-octabaix-study
#5
Assumpta Ferrer, Francesc Formiga, Héctor Sanz, Jesús Almeda, Glòria Padrós
BACKGROUND: The population is aging and multimorbidity is becoming a common problem in the elderly. OBJECTIVE: To explore the effect of multimorbidity patterns on mortality for all causes at 3- and 5-year follow-up periods. MATERIALS AND METHODS: A prospective community-based cohort (2009-2014) embedded within a randomized clinical trial was conducted in seven primary health care centers, including 328 subjects aged 85 years at baseline. Sociodemographic variables, sensory status, cardiovascular risk factors, comorbidity, and geriatric tests were analyzed...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28182778/epidemiology-of-multimorbidity-within-the-brazilian-adult-general-population-evidence-from-the-2013-national-health-survey-pns-2013
#6
Magdalena Rzewuska, João Mazzoncini de Azevedo-Marques, Domenica Coxon, Maria Lúcia Zanetti, Ana Carolina Guidorizzi Zanetti, Laercio Joel Franco, Jair Lício Ferreira Santos
Middle-income countries are facing a growing challenge of adequate health care provision for people with multimorbidity. The objectives of this study were to explore the distribution of multimorbidity and to identify patterns of multimorbidity in the Brazilian general adult population. Data from 60202 adults, aged ≥18 years that completed the individual questionnaire of the National Health Survey 2013 (Portuguese: "Pesquisa Nacional de Saúde"-"PNS") was used. We defined multimorbidity as the presence of two or more chronic conditions, including self-reported diagnoses and responses to the 9-item Patient Health Questionnaire for depression...
2017: PloS One
https://www.readbyqxmd.com/read/28107252/multimorbidity-and-the-risk-of-all-cause-30-day-readmission-in-the-setting-of-multidisciplinary-management-of-chronic-heart-failure-a-retrospective-analysis-of-830-hospitalized-patients-in-australia
#7
Joshua F Wiley, Yih-Kai Chan, Yasmin Ahamed, Jocasta Ball, Melinda J Carrington, Barbara Riegel, Simon Stewart
BACKGROUND: Multimorbidity has an adverse effect on health outcomes in hospitalized individuals with chronic heart failure (CHF), but the modulating effect of multidisciplinary management is unknown. OBJECTIVE: The aim of this study was to test the hypothesis that increasing morbidity would independently predict an increasing risk of 30-day readmission despite multidisciplinary management of CHF. METHODS: We studied patients hospitalized for any reason with heart failure receiving nurse-led, postdischarge multidisciplinary management...
January 20, 2017: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28056050/a-latent-class-analysis-of-multimorbidity-and-the-relationship-to-socio-demographic-factors-and-health-related-quality-of-life-a-national-population-based-study-of-162-283-danish-adults
#8
Finn Breinholt Larsen, Marie Hauge Pedersen, Karina Friis, Charlotte Glümer, Mathias Lasgaard
OBJECTIVES: To identify patterns of multimorbidity in the general population and examine how these patterns are related to socio-demographic factors and health-related quality of life. STUDY DESIGN AND SETTING: We used latent class analysis to identify subgroups with statistically distinct and clinically meaningful disease patterns in a nationally representative sample of Danish adults (N = 162,283) aged 16+ years. The analysis was based on 15 chronic diseases. RESULTS: Seven classes with different disease patterns were identified: a class with no or only a single chronic condition (59% of the population) labeled "1) Relatively Healthy" and six classes with a very high prevalence of multimorbidity labeled; "2) Hypertension" (14%); "3) Musculoskeletal Disorders" (10%); "4) Headache-Mental Disorders" (7%); "5) Asthma-Allergy" (6%); "6) Complex Cardiometabolic Disorders" (3%); and "7) Complex Respiratory Disorders" (2%)...
2017: PloS One
https://www.readbyqxmd.com/read/28029586/social-determinants-multimorbidity-and-patterns-of-end-of-life-care-in-older-adults-dying-from-cancer
#9
Siran M Koroukian, Nicholas K Schiltz, David F Warner, Charles W Given, Mark Schluchter, Cynthia Owusu, Nathan A Berger
OBJECTIVE: Most prior studies on aggressive end-of-life care in older patients with cancer have accounted for social determinants of health (e.g., race, income, and education), but rarely for multimoribidity (MM). In this study, we examine the association between end-of-life care and each of the social determinants of health and MM, hypothesizing that higher MM is associated with less aggressive care. METHODS: From the linked 1991-2008 Health and Retirement Study, Medicare data, and the National Death Index, we identified fee-for-service patients age ≥66years who died from cancer (n=835)...
October 28, 2016: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/28003289/burden-of-multimorbidity-in-relation-to-age-gender-and-immigrant-status-a-cross-sectional-study-based-on-administrative-data
#10
Jacopo Lenzi, Vera Maria Avaldi, Paola Rucci, Giulia Pieri, Maria Pia Fantini
OBJECTIVES: Many studies have investigated multimorbidity, whose prevalence varies according to settings and data sources. However, few studies on this topic have been conducted in Italy, a country with universal healthcare and one of the most aged populations in the world. The aim of this study was to estimate the prevalence of multimorbidity in a Northern Italian region, to investigate its distribution by age, gender and citizenship and to analyse the correlations of diseases. DESIGN: Cross-sectional study based on administrative data...
December 21, 2016: BMJ Open
https://www.readbyqxmd.com/read/27998377/relationship-of-sleep-duration-with-socio-demographic-characteristics-lifestyle-mental-health-and-chronic-diseases-in-a-large-chinese-adult-population
#11
Shibin Wang, Bo Li, Yanhua Wu, Gabor S Ungvari, Chee H Ng, Yingli Fu, Changgui Kou, Yaqin Yu, Hong-Qiang Sun, Yu-Tao Xiang
STUDY OBJECTIVES: Pattern of sleep duration and its correlates have rarely been reported in China. This study examined the sleep duration and its relationship with sociodemographic variables, lifestyle, mental health, and chronic diseases in a large Chinese adult population. METHODS: This cross-sectional study used multistage stratified cluster sampling. A total of 17,320 participants from Jilin province were selected and interviewed using standardized assessment tools...
December 16, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27942744/which-long-term-illnesses-do-patients-find-most-limiting-a-census-based-cross-sectional-study-of-340-000-people
#12
David M Wright, Michael Rosato, Dermot O'Reilly
OBJECTIVES: To investigate associations between a widely used measure of self-assessed health (limiting long-term illness, LLTI) and 11 long-term health conditions. METHODS: Information on LLTI and health conditions was obtained from 2011 Census returns for a 28% representative sample of the Northern Ireland population (n = 342,868). Logistic regression was used to predict LLTI by sex and age group for each condition found in isolation, adjusting for marital status, social class, household car access, housing tenure, and educational attainment...
December 9, 2016: International Journal of Public Health
https://www.readbyqxmd.com/read/27880051/multimorbidities-of-asthma-allergies-and-airway-illnesses-in-childhood-chance-or-not-chance
#13
Wei Liu, Chen Huang, Xueying Wang, Jiao Cai, Yu Hu, Zhijun Zou, Louise B Weschler, Li Shen, Jan Sundell
OBJECTIVES: We investigated patterns of multimorbidities among asthma, allergies, and respiratory illnesses in preschool children. We investigated multimorbidities of lifetime asthma, allergic rhinitis, eczema, food allergy, pneumonia, and ear infections; and multimorbidities of current (in the last year before the survey) wheeze, dry cough, rhinitis, eczema, and common cold during childhood. We further analyzed whether prevalences of these multimorbidities were due to chance. METHODS: A cross-sectional study was conducted in 72 kindergartens of Shanghai, China...
November 23, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27876455/multiple-morbidities-in-companion-dogs-a-novel-model-for-investigating-age-related-disease
#14
Kelly Jin, Jessica M Hoffman, Kate E Creevy, Dan G O'Neill, Daniel E L Promislow
The proportion of men and women surviving over 65 years has been steadily increasing over the last century. In their later years, many of these individuals are afflicted with multiple chronic conditions, placing increasing pressure on healthcare systems. The accumulation of multiple health problems with advanced age is well documented, yet the causes are poorly understood. Animal models have long been employed in attempts to elucidate these complex mechanisms with limited success. Recently, the domestic dog has been proposed as a promising model of human aging for several reasons...
2016: Pathobiology of Aging & Age related Diseases
https://www.readbyqxmd.com/read/27871281/physical-multimorbidity-and-psychosis-comprehensive-cross-sectional-analysis-including-242-952-people-across-48-low-and-middle-income-countries
#15
Brendon Stubbs, Ai Koyanagi, Nicola Veronese, Davy Vancampfort, Marco Solmi, Fiona Gaughran, André F Carvalho, John Lally, Alex J Mitchell, James Mugisha, Christoph U Correll
BACKGROUND: In people with psychosis, physical comorbidities, including cardiovascular and metabolic diseases, are highly prevalent and leading contributors to the premature mortality encountered. However, little is known about physical health multimorbidity in this population or in people with subclinical psychosis and in low- and middle-income countries (LMICs). This study explores physical health multimorbidity patterns among people with psychosis or subclinical psychosis. METHODS: Overall, data from 242,952 individuals from 48 LMICs, recruited via the World Health Survey, were included in this cross-sectional study...
November 22, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27809772/the-burden-of-cardiovascular-morbidity-in-a-european-mediterranean-population-with-multimorbidity-a-cross-sectional-study
#16
Concepción Violán, Néker Bejarano-Rivera, Quintí Foguet-Boreu, Albert Roso Llorach, Mariona Pons-Vigués, Miguel Martin Mateo, Enriqueta Pujol-Ribera
BACKGROUND: Cardiovascular diseases are highly represented in multimorbidity patterns. Nevertheless, few studies have analysed the burden of these diseases in the population with multimorbidity. The objective of this study was to identify and describe the cardiovascular diseases among the patients with multimorbidity. METHODS: We designed a cross-sectional study in patients ≥19 years old assigned to 251 primary health care centres in Catalonia, Spain. The main outcome was cardiovascular morbidity burden, defined as the presence of one or more of 24 chronic cardiovascular diseases in multimorbid patients (≥2 chronic conditions)...
November 3, 2016: BMC Family Practice
https://www.readbyqxmd.com/read/27753745/identifying-specific-combinations-of-multimorbidity-that-contribute-to-health-care-resource-utilization-an-analytic-approach
#17
Nicholas K Schiltz, David F Warner, Jiayang Sun, Paul M Bakaki, Avi Dor, Charles W Given, Kurt C Stange, Siran M Koroukian
BACKGROUND: Multimorbidity affects the majority of elderly adults and is associated with higher health costs and utilization, but how specific patterns of morbidity influence resource use is less understood. OBJECTIVE: The objective was to identify specific combinations of chronic conditions, functional limitations, and geriatric syndromes associated with direct medical costs and inpatient utilization. DESIGN: Retrospective cohort study using the Health and Retirement Study (2008-2010) linked to Medicare claims...
March 2017: Medical Care
https://www.readbyqxmd.com/read/27718526/multimorbidity-patterns-of-oral-clinical-conditions-social-position-and-oral-health-related-quality-of-life-in-a-population-based-survey-of-12-yr-old-children
#18
Mario V Vettore, Gabriela de F Meira, Maria A B Rebelo, Janete M Rebelo Vieira, Carolina Machuca
The aim of this study was to describe the patterns of multimorbidities of oral clinical conditions in children. The association between social position and number of oral clinical conditions, and the relationship of social position and number of oral clinical conditions with oral health-related quality of life [OHRQoL, measured using the Brazilian Child-Oral Impacts on Daily Performance (Child-OIDP)] were also investigated. The study analysed data on 7,208 children, 12 yr of age, from the Brazilian Oral Health Survey (SBBrasil Project)...
December 2016: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/27697796/spatial-associations-of-multiple-chronic-conditions-among-older-adults
#19
Ellen K Cromley, Maureen Wilson-Genderson, Allison R Heid, Rachel A Pruchno
Multimorbidity, the presence of two or more chronic conditions in an individual, presents a major challenge for meeting the health care needs of older adults. This study advances understanding of multiple chronic conditions by using local colocation quotients to reveal spatial associations for five chronic conditions (arthritis, diabetes, heart disease, hypertension, and pulmonary disease) in a statewide panel of older adults in New Jersey. Among adults with three or more conditions, large concentrations of Arthritis-Heart Disease-Pulmonary Disease, Arthritis-Hypertension-Pulmonary Disease, and Diabetes-Heart Disease-Hypertension were observed, each triad located in different regions of the state...
October 2, 2016: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/27687902/do-baby-boomers-use-more-healthcare-services-than-other-generations-longitudinal-trajectories-of-physician-service-use-across-five-birth-cohorts
#20
Mayilee Canizares, Monique Gignac, Sheilah Hogg-Johnson, Richard H Glazier, Elizabeth M Badley
OBJECTIVE: In light of concerns for meeting the provision of healthcare services given the large numbers of ageing baby boomers, we compared the trajectories of primary care and specialist services use across the lifecourse of 5 birth cohorts and examined factors associated with birth cohort differences. DESIGN: Longitudinal panel. SETTING: Canadian National Population Health Survey (1994-2011). POPULATION: Sample of 10 186 individuals aged 20-69 years in 1994-1995 and who were from 5 birth cohorts: Generation X (Gen X; born: 1965-1974), Younger Baby Boomers (born: 1955-1964), Older Baby Boomers (born: 1945-1954), World War II (born: 1935-1944) and pre-World War II (born: 1925-1934)...
2016: BMJ Open
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