Ashley Richardson, Liza Dadone, Matthew Johnston, Priya Bapodra-Villaverde, Amy Schilz, Eunice Contreras, Anne Rivas, Sarah Schwenzer, Stephanie Zec, Brenda Cordova, Sara Ferguson, Krista E Banks, Daniel L Gustafson, Miranda J Sadar
Growing resistance to current antiparasitic medications, both in livestock and in zoological species under human care, makes it imperative to evaluate available drugs on the market, such as eprinomectin. In this prospective study, five males and one female of reticulated ( Giraffa reticulata ; n = 2), Masai ( Giraffa tippelskirchii ; n = 1), Nubian ( Giraffa camelopardalis ; n = 2), and hybrid subspecies ( n = 1) of giraffe, received 1.5 mg/kg eprinomectin topically along the dorsum. Using high-performance liquid chromatography, concentrations of eprinomectin in plasma samples collected at 0, 4, 24, and 48 h, and 7, 14, 21, and 28 d were evaluated following drug administration...
March 2024: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians