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Myocardial perfusion scan

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https://www.readbyqxmd.com/read/28540211/delayed-enhancement-cardiac-computed-tomography-for-the-assessment-of-myocardial-infarction-from-bench-to-bedside
#1
REVIEW
Gaston A Rodriguez-Granillo
A large number of studies support the increasingly relevant prognostic value of the presence and extent of delayed enhancement (DE), a surrogate marker of fibrosis, in diverse etiologies. Gadolinium and iodinated based contrast agents share similar kinetics, thus leading to comparable myocardial characterization with cardiac magnetic resonance (CMR) and cardiac computed tomography (CT) at both first-pass perfusion and DE imaging. We review the available evidence of DE imaging for the assessment of myocardial infarction (MI) using cardiac CT (CTDE), from animal to clinical studies, and from 16-slice CT to dual-energy CT systems (DECT)...
April 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28540209/myocardial-blood-flow-quantification-for-evaluation-of-coronary-artery-disease-by-computed-tomography
#2
REVIEW
Filippo Cademartiri, Sara Seitun, Alberto Clemente, Ludovico La Grutta, Patrizia Toia, Giuseppe Runza, Massimo Midiri, Erica Maffei
During the last decade coronary computed tomography angiography (CTA) has become the preeminent non-invasive imaging modality to detect coronary artery disease (CAD) with high accuracy. However, CTA has a limited value in assessing the hemodynamic significance of a given stenosis due to a modest specificity and positive predictive value. In recent years, different CT techniques for detecting myocardial ischemia have emerged, such as CT-derived fractional flow reserve (FFR-CT), transluminal attenuation gradient (TAG), and myocardial CT perfusion (CTP) imaging...
April 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28528431/rapid-rest-stress-regadenoson-ungated-perfusion-cmr-for-detection-of-coronary-artery-disease-in-patients-with-atrial-fibrillation
#3
Erik T Bieging, I Haider, G Adluru, L Chang, P Suksaranjit, D Likhite, A Shaaban, L Jensen, B D Wilson, C J McGann, E DiBella
Cardiovascular magnetic resonance (CMR) perfusion has been established as a useful imaging modality for the detection of coronary artery disease (CAD). However, there are several limitations when applying standard, ECG-gated stress/rest perfusion CMR to patients with atrial fibrillation (AF). In this study we investigate an approach with no ECG gating and a rapid rest/stress perfusion protocol to determine its accuracy for detection of CAD in patients with AF. 26 patients with AF underwent a rapid rest/regadenoson stress CMR perfusion imaging protocol, and all patients had X-ray coronary angiography...
May 20, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28526044/clinical-outcomes-meta-analysis-measuring-subendocardial-perfusion-and-efficacy-of-transmyocardial-laser-revascularization-with-nuclear-imaging
#4
REVIEW
Jessika Iwanski, Shannon M Knapp, Ryan Avery, Isabel Oliva, Raymond K Wong, Raymond B Runyan, Zain Khalpey
INTRODUCTION: Randomized and nonrandomized clinical trials have tried to assess whether or not TMR patients experience an increase in myocardial perfusion. However there have been inconsistencies reported in the literature due to the use of different nuclear imaging modalities to test this metric. The primary purpose of this meta-analysis was to determine whether SPECT, MUGA and PET scans demonstrate changes in myocardial perfusion between lased and non-lased subjects and whether laser type affects myocardial perfusion...
May 19, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28523283/variable-temporal-sampling-and-tube-current-modulation-for-myocardial-blood-flow-estimation-from-dose-reduced-dynamic-computed-tomography
#5
Dimple Modgil, Michael D Bindschadler, Adam M Alessio, Patrick J La Rivière
Quantification of myocardial blood flow (MBF) can aid in the diagnosis and treatment of coronary artery disease. However, there are no widely accepted clinical methods for estimating MBF. Dynamic cardiac perfusion computed tomography (CT) holds the promise of providing a quick and easy method to measure MBF quantitatively. However, the need for repeated scans can potentially result in a high patient radiation dose, limiting the clinical acceptance of this approach. In our previous work, we explored techniques to reduce the patient dose by either uniformly reducing the tube current or by uniformly reducing the number of temporal frames in the dynamic CT sequence...
April 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28504545/detection-of-hemodynamically-significant-coronary-artery-stenosis-with-ct-enhancement-ratio-a-validation-study-in-a-porcine-model
#6
Jun Chen, Yang Pu, Zhang Zhang, Xuefang Yu, Zhengwen Yang
OBJECTIVE: Although numerous techniques that are based on CT number analysis have been proposed, the assessment of hemodynamically significant coronary artery stenosis remains a great challenge. The purpose of this study is to validate use of the CT enhancement ratio in the detection of hemodynamically significant coronary artery stenosis in a porcine model. MATERIALS AND METHODS: Experiments involving eight closed-chest swine were performed. A balloon catheter was placed into the left anterior descending coronary artery to simulate different degrees of luminal stenosis...
May 15, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28489691/optimal-injected-dose-ratio-of-a-very-rapid-1-day-protocol-of-myocardial-perfusion-imaging-with-cadmium-zinc-telluride-single-photon-emission-tomography-simulation-and-phantom-study
#7
Minako Shinjyo, Maho Naniwa, Narumi Kubo, Yoshihiro Nishimura, Keisuke Kiso, Kazuki Fukuchi
OBJECTIVE: Cadmium-zinc-telluride detectors enable shorter acquisition durations in myocardial perfusion imaging (MPI), but the time interval of sequential scanning is still unchanged in clinical practice. We designed a very rapid 1-day protocol of MPI using cadmium-zinc-telluride single-photon emission tomography and evaluated the optimal dose ratio between two scanning acquisitions by means of simulations and phantom experiments. METHODS: We intended to perform a 1-day MPI within 140 min and simulate radioactivities in the second scan under various injected dose ratios...
May 9, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28484986/validation-of-a-clinical-pathway-to-assess-asymptomatic-renal-transplant-candidates-using-myocardial-perfusion-imaging
#8
Rami Doukky, Ibtihaj Fughhi, Tania Campagnoli, Marwan Wassouf, Michael Kharouta, Aviral Vij, Chiedozie Anokwute, Andrew Appis, Amjad Ali
BACKGROUND: An AHA/ACCF scientific statement proposed 8 risk factors to assess the need for noninvasive coronary artery disease (CAD) surveillance in asymptomatic patients undergoing evaluation for kidney transplantation. The clinical application of these risk factors and the role of noninvasive testing in this context have not been defined. METHODS AND RESULTS: We retrospectively followed a cohort of 581 consecutive kidney transplant recipients of whom 401 had pre-transplant radionuclide myocardial perfusion imaging (MPI) and 90 had pre-transplant coronary angiography...
May 8, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28469688/significance-of-abnormal-myocardial-perfusion-scans-in-candidates-for-orthotopic-liver-transplantation
#9
Atefe Esmaili, Saeed Farzanefar, Alireza Emami-Ardakani, Mehrshad Abbasi
Background: The implications of cardiac risk stratification before orthotopic liver transplantation (OLT) are not well established. We studied the usefulness of myocardial perfusion imaging (MPI) in this scenario. Methods: MPI data of 24 patients (9 females), candidates of OLT, were collected. They underwent MPI as part of their preoperative risk assessment. MPIs were interpreted by 2 nuclear physicians, who had access to clinical data, scan, and semi-quantification results (i.e., quantitative perfusion single-photon emission tomography (SPECT) [QPS] and quantitative gated SPECT [QGS])...
January 2017: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/28456317/long-term-prognostic-value-of-appropriate-myocardial-perfusion-imaging
#10
Angela S Koh, Weng Kit Lye, Shaw Yang Chia, Jennifer Salunat-Flores, Ling L Sim, Felix Y J Keng, Ru San Tan, Terrance S J Chua
Appropriate use criteria (AUC) for single-photon emission computed tomography myocardial perfusion images (SPECT-MPIs) were developed to address the growth of cardiac imaging studies. Long-term prognostic value of AUC in SPECT-MPI has not been tested in existing cohorts. We sought to determine the long-term prognostic value of MPI classified as appropriate. AUC was evaluated in a prospectively designed cohort of patients who underwent clinically indicated MPI. MPI studies were classified based on 2009 AUC for SPECT-MPI...
March 29, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28454833/changes-in-cardiovascular-medication-after-coronary-artery-calcium-scanning-and-normal-single-photon-emission-computed-tomography-myocardial-perfusion-imaging-in-symptomatic-patients
#11
Elsemiek M Engbers, Jorik R Timmer, Mohamed Mouden, Siert Knollema, Pieter L Jager, Jan Paul Ottervanger
The impact of coronary artery calcium (CAC) scoring on subsequent changes in cardiovascular medication use in symptomatic patients with normal myocardial perfusion imaging (MPI) findings is not well established. The aim of the current study was to evaluate changes in aspirin and statin use in patients suspected for coronary artery disease after CAC scoring and normal single photon emission computed tomography (SPECT) MPI. METHODS: In the current study, 1,033 stable symptomatic patients without a known history of coronary artery disease with normal SPECT MPI who underwent concomitant CAC scoring were included...
April 2017: American Heart Journal
https://www.readbyqxmd.com/read/28450561/prognostic-value-of-myocardial-perfusion-imaging-with-czt-spect-camera-in-patients-suspected-for-coronary-artery-disease
#12
Elsemiek M Engbers, Jorik R Timmer, Mohamed Mouden, Siert Knollema, Pieter L Jager, Jan Paul Ottervanger
The prognostic value of myocardial perfusion imaging (MPI) with the cadmium zinc telluride (CZT) single photon emission computed tomography (SPECT) camera is not well established. Therefore, the aim of the current study was to evaluate the prognostic value of MPI performed with a CZT SPECT camera in a large cohort of patients suspected for coronary artery disease (CAD). Methods: 4057 consecutive symptomatic stable patients without a history of CAD underwent CZT SPECT MPI. During a median follow-up of 2.4 years (25th-75th percentile:1...
April 27, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28409258/impact-of-knowledge-based-iterative-model-reconstruction-on-myocardial-late-iodine-enhancement-in-computed-tomography-and-comparison-with-cardiac-magnetic-resonance
#13
Yuki Tanabe, Teruhito Kido, Akira Kurata, Naoki Fukuyama, Takahiro Yokoi, Tomoyuki Kido, Teruyoshi Uetani, Mani Vembar, Amar Dhanantwari, Shinichi Tokuyasu, Natsumi Yamashita, Teruhito Mochizuki
We evaluated the image quality and diagnostic performance of late iodine enhancement computed tomography (LIE-CT) with knowledge-based iterative model reconstruction (IMR) for the detection of myocardial infarction (MI) in comparison with late gadolinium enhancement magnetic resonance imaging (LGE-MRI). The study investigated 35 patients who underwent a comprehensive cardiac CT protocol and LGE-MRI for the assessment of coronary artery disease. The CT protocol consisted of stress dynamic myocardial CT perfusion, coronary CT angiography (CTA) and LIE-CT using 256-slice CT...
April 13, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28395422/-dynamic-detection-of-surface-blood-flow-in-rat-heart-and-its-application-in-real-time-identification-of-myocardial-infarction-model
#14
Q Lei, C Chen, X L Wu, W J Chen, T Yi, M D Ma, Y He, X R Shui, S A Huang, C Chen, W Lei
Objective: To establish a method for monitoring the surface blood flow in the heart of rats, and to clarify the relationship between the degree of myocardial infarction and the blood perfusion on the surface of the heart, so as to provide a new indicator for the identification of rat myocardial infarction model. Methods: The rats were divided into control group (n=23) and model group (n=107), the rat hearts were scanned by the laser doppler perfusion imager before and after operation respectively, and the data was analyzed to acquire the rate of surface blood flow change of the heart...
April 4, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28379843/direct-parametric-reconstruction-in-dynamic-pet-myocardial-perfusion-imaging-in-vivo-studies
#15
Yoann Petibon, Yothin Rakvongthai, Georges El Fakhri, Jinsong Ouyang
Dynamic PET myocardial perfusion imaging (MPI) used in conjunction with tracer kinetic modeling enables the quantification of absolute myocardial blood flow (MBF). However, MBF maps computed using the traditional indirect method (i.e. post-reconstruction voxel-wise fitting of kinetic model to PET time-activity-curves-TACs) suffer from poor signal-to-noise ratio (SNR). Direct reconstruction of kinetic parameters from raw PET projection data has been shown to offer parametric images with higher SNR compared to the indirect method...
April 5, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28378112/automatic-determination-of-cardiovascular-risk-by-ct-attenuation-correction-maps-in-rb-82-pet-ct
#16
Ivana Išgum, Bob D de Vos, Jelmer M Wolterink, Damini Dey, Daniel S Berman, Mathieu Rubeaux, Tim Leiner, Piotr J Slomka
BACKGROUND: We investigated fully automatic coronary artery calcium (CAC) scoring and cardiovascular disease (CVD) risk categorization from CT attenuation correction (CTAC) acquired at rest and stress during cardiac PET/CT and compared it with manual annotations in CTAC and with dedicated calcium scoring CT (CSCT). METHODS AND RESULTS: We included 133 consecutive patients undergoing myocardial perfusion (82)Rb PET/CT with the acquisition of low-dose CTAC at rest and stress...
April 4, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28364376/incidental-spade-shaped-fdg-uptake-in-the-left-ventricular-apex-suggests-apical-hypertrophic-cardiomyopathy
#17
Mari Katagiri, Tadaki Nakahara, Mitsushige Murata, Yuji Ogata, Yohji Matsusaka, Yu Iwabuchi, Yoshitake Yamada, Keiichi Fukuda, Masahiro Jinzaki
PURPOSE: Apical wall thickening with an "ace-of-spades" configuration is a unique sign of apical hypertrophic cardiomyopathy (AHCM). We investigated spade-shaped FDG uptake around the left ventricular apex (SSUA) incidentally found in routine oncological FDG PET. METHODS: Cases showing SSUA were selected based on retrospective review. The pattern or intensity of SSUA was compared with the results of electrocardiogram (ECG), echocardiography, and stress myocardial perfusion SPECT...
March 31, 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/28361475/factors-affecting-appearance-of-a-normal-myocardial-perfusion-scan
#18
EDITORIAL
Piotr Slomka, Guido Germano
No abstract text is available yet for this article.
March 30, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28357812/clinical-performance-of-rb-82-myocardial-perfusion-pet-and-tc-99m-based-spect-in-patients-with-extreme-obesity
#19
David T Harnett, Samir Hazra, Ronnen Maze, Brian A Mc Ardle, Ali Alenazy, Trevor Simard, Ellen Henry, Girish Dwivedi, Christopher Glover, Robert A deKemp, Ross A Davies, Terrence D Ruddy, Benjamin J W Chow, Rob S Beanlands, Benjamin Hibbert
BACKGROUND: We evaluated the performance of stress imaging with technetium-99m-labeled tetrofosmin single-photon emission computed tomography (SPECT) and rubidium-82 positron emission tomography (PET) in patients with extreme obesity, defined as body mass index ≥40 kg/m(2). METHODS: We identified patients with extreme obesity who underwent angiography in our center and either stress SPECT or PET within the previous six months. Cohorts of patients with extreme obesity and a <5% pretest likelihood of CAD who underwent SPECT (N = 25) or PET (N = 25) were also included...
March 29, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28288480/the-effect-of-heart-rate-on-exposure-window-and-best-phase-for-stress-perfusion-computed-tomography-lessons-from-the-core320-study
#20
MULTICENTER STUDY
Chloe Steveson, Joanne D Schuijf, Andrea L Vavere, Richard T Mather, Teresa Caton, Vishal Mehra, Aisha Betoko, Christopher Cox, Joao Ac Lima, Richard T George
OBJECTIVES: The aim of this study is to evaluate the effect of heart rate on exposure window, best phase, and image quality for stress computed tomography perfusion (CTP) in the CORE320 study. METHODS: The CTP data sets were analyzed to determine the best phase for perfusion analysis. A predefined exposure window covering 75% to 95% of the R-R cycle was used. RESULTS: Of the 368 patients included in the analysis, 93% received oral β blockade before the rest scan...
March 2017: Journal of Computer Assisted Tomography
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