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Myocardial perfusion scan

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https://www.readbyqxmd.com/read/27909770/the-natural-history-of-takotsubo-syndrome-a-two-year-follow-up-study-with-myocardial-sympathetic-and-perfusion-g-spect-imaging
#1
Stelvio Sestini, Francesco Pestelli, Mario Leoncini, Francesco Bellandi, Christian Mazzeo, Luigi Mansi, Ignasi Carrio, Antonio Castagnoli
PURPOSE: To investigate changes in sympathetic activity, perfusion, and left ventricular (LV) functionality in takotsubo cardiomyopathy (TTC) patients from onset (T0) to post-onset conditions at 1 month (T1), 1-2 years (T2, T3). METHODS: Twenty-two patients (70 ± 11 years) underwent serial gated single photon emission tomography (G-SPECT) studies with (123)I-mIBG and (99m)Tc-Sestamibi. Statistics were performed using ANOVA/Sheffé post-hoc, correlation test, and receiver operating characteristic (ROC) curve analysis (p < 0...
December 1, 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27893992/prediction-of-myocardial-infarction-by-assessing-regional-cardiac-wall-in-cmr-images-through-active-mesh-modeling
#2
Hossein Yousefi-Banaem, Saeed Kermani, Sasan Asiaei, Hamid Sanei
Myocardial infarction is a leading cause of morbidity and mortality. In this study, using Cine MRI images, the infarct region was precisely determined by examining the local migration path length of critical points on myocardium borders and the fractional thickening effects. First, MRI Cine images of Epi/Endocardium were processed in 3D for all slices, and then incorporated in all frames to build a dynamic model. Epi/Endocardium images were segmented using Heiberg algorithm, and then by a robust restricted block matching algorithm, the sparse points were tracked...
November 14, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27871168/long-term-prognosis-of-end-stage-renal-disease-patients-with-normal-myocardial-perfusion-as-determined-by-single-photon-emission-computed-tomography
#3
Gun Ha Park, Jae Won Song, Chang Min Lee, Young Rim Song, Sung Gyun Kim, Hyung Jik Kim, Jwa Kyung Kim
Background/Aims: Normal myocardial perfusion is closely associated with very low rates of cardiac events and better long-term outcomes; however, little is known about its prognostic value in patients with end-stage renal disease (ESRD). Methods: A total of 286 incident patients underwent baseline cardiac evaluations using echocardiography and stress-rest single-photon emission computed tomography. Perfusion scans for 177 patients (61.9%) who had a summed stress score (SSS) < 4 were normal...
November 22, 2016: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/27858346/single-ct-for-attenuation-correction-of-rest-stress-cardiac-spect-perfusion-imaging
#4
R Glenn Wells, Mikael Trottier, Manuja Premaratne, Karen Vanderwerf, Terrence D Ruddy
Common practice is to use separate CT scans acquired during rest and stress for attenuation correction of SPECT myocardial perfusion imaging (MPI). We evaluated using a single CT scan to correct both rest and stress SPECT scans. Studies from 154 patients were reprocessed using one CT acquired at stress to correct both rest and stress scans (1CT) and compared to correction of each scan with its own CT (2CT). Two expert readers independently read the images and determined summed stress (SSS), rest (SRS), and difference (SDS) scores...
November 17, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27858344/association-between-non-perfusion-parameters-and-presence-of-ischemia-in-gated-spect-myocardial-perfusion-imaging-studies
#5
Amalia Peix, Lázaro O Cabrera, Kenia Padrón, Lydia Rodríguez, Jesús Fernández, Giselle López, Regla Carrillo, Erick Mena, Yoel Fernández, Maurizio Dondi, Diana Páez
BACKGROUND: Combined assessment of perfusion and function improves diagnostic and prognostic power of gated-SPECT in patients with coronary artery disease. The aim of this study was to investigate whether the presence of stress-induced ischemia is associated with abnormal resting left ventricular (LV) function and intraventricular dyssynchrony. METHODS AND RESULTS: Gated-SPECT myocardial perfusion imaging (MPI) at rest and 15 min post-stress was performed in 101 patients, who were divided into three groups: those with stress-induced ischemia (Group 1, n = 58), those with normal scans (Group 2, n = 28), and those with scar but no ischemia (Group 3, n = 15)...
November 17, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27848163/myocardial-ischemia-detection-with-single-phase-ct-perfusion-in-symptomatic-patients-using-high-pitch-helical-image-acquisition-technique
#6
Bernhard Bischoff, Simon Deseive, Martin Rampp, Andrei Todica, Marc Wermke, Stefan Martinoff, Steffen Massberg, Maximilian F Reiser, Hans-Christoph Becker, Jörg Hausleiter
Coronary CT angiography (CCTA) suffers from a reduced diagnostic accuracy in patients with heavily calcified coronary arteries or prior myocardial revascularisation due to artefacts caused by calcifications and stent material. CT myocardial perfusion imaging (CTMPI) yields high potential for the detection of myocardial ischemia and might help to overcome the above mentioned limitations. We analysed CT single-phase perfusion using high-pitch helical image acquisition technique in patients with prior myocardial revascularisation...
November 15, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27816974/troponin-i-and-d-dimer-for-discriminating-acute-pulmonary-thromboembolism-from-myocardial-infarction
#7
Soo Jin Kim, Moo Hyun Kim, Kwang Min Lee, Tae Hyung Kim, Sun Yong Choi, Min Kook Son, Ji Woen Park, Victor L Serebruany
BACKGROUND: Acute pulmonary thromboembolism (APTE) is a life-threatening condition, often manifesting with chest pain, dyspnea, and increased cardiac biomarkers including cardiac troponin I (CTI) and D-dimer. Therefore, APTE is often misdiagnosed with classical non-ST elevation myocardial infarction (NSTEMI), resulting in unnecessary coronary interventions and a delay of therapy. OBJECTIVES: Our aim was to distinguish APTE from NSTEMI based on CTI and D-dimer levels...
November 5, 2016: Cardiology
https://www.readbyqxmd.com/read/27815793/cardiovascular-magnetic-resonance-in-patients-with-magnetic-resonance-conditional-pacemaker-systems-at-1-5%C3%A2-t-influence-of-pacemaker-related-artifacts-on-image-quality-including-first-pass-perfusion-aortic-and-mitral-valve-assessment-flow-measurement-short
#8
REVIEW
Oliver Klein-Wiele, Marietta Garmer, Martin Busch, Serban Mateiescu, Rhyan Urbien, Gianluca Barbone, Kaffer Kara, Michael Schulte-Hermes, Frauke Metz, Birgit Hailer, Dietrich Grönemeyer
There are only limited data on the impact of device-related artifacts on image quality in cardiovascular magnetic resonance imaging (CMR) in patients with pacemakers (PM). Adenosine stress perfusion, T1-weighted imaging and flow measurement as well as valve characterization have not been evaluated previously concerning artifact burden. We aimed to assess image quality in all routinely used CMR sequences. We analyzed 2623 myocardial segments in CMR scans of 61 patients with MR conditional PM (mean age 72.1 ± 11...
November 4, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27804072/long-term-prognostic-value-of-coronary-artery-calcium-scanning-coronary-computed-tomographic-angiography-and-stress-myocardial-perfusion-imaging-in-patients-with-suspected-coronary-artery-disease
#9
Carmela Nappi, Emanuele Nicolai, Stefania Daniele, Wanda Acampa, Valeria Gaudieri, Roberta Assante, Emilia Zampella, Sabrina Segreto, Massimo Imbriaco, Mario Petretta, Marco Salvatore, Alberto Cuocolo
BACKGROUND: We compared the long-term prognostic value of coronary artery calcium (CAC) scanning, coronary computed tomographic angiography (CCTA), and stress single-photon emission computed tomography myocardial perfusion imaging (MPI) in patients with suspected coronary artery disease (CAD). METHODS AND RESULTS: A total of 164 patients were studied. CAC score was measured according to the Agatston method and patients were categorized into 3 groups (0, 1-300, and >300)...
November 1, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27801740/impact-of-time-of-flight-reconstruction-on-cardiac-pet-images-of-obese-patients
#10
Frank P DiFilippo, Richard C Brunken
PURPOSE: The benefit of time-of-flight (TOF) information in PET oncology studies is well established, demonstrating improved signal-to-noise ratio and enhanced lesion detection. In cardiac PET studies, tracer distribution and study interpretation differ substantially from oncology PET, and the benefit of TOF is less established. We investigate the impact of TOF on reconstructed myocardial distribution in Rb PET perfusion studies of obese patients, for whom TOF would have most significant impact...
October 31, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27795485/optimal-scan-time-for-single-phase-myocardial-computed-tomography-perfusion-to-detect-myocardial-ischemia%C3%A3-derivation-cohort-from-dynamic-myocardial-computed-tomography-perfusion
#11
Yuki Tanabe, Teruhito Kido, Akira Kurata, Teruyoshi Uetani, Naoki Fukuyama, Takahiro Yokoi, Hikaru Nishiyama, Tomoyuki Kido, Masao Miyagawa, Teruhito Mochizuki
BACKGROUND: Single-phase myocardial computed tomography perfusion (CTP) is useful for detecting myocardial ischemia, but determining the optimal scan time is difficult. The present study evaluated this by analyzing dynamic CTP data.Methods and Results:We retrospectively selected 32 patients, all of whom had undergone stress dynamic CTP and magnetic resonance myocardial perfusion imaging (MR-MPI). Myocardial ischemia was assessed by MR-MPI using the 16-segment model. Whole-heart dynamic CTP data were acquired for 30 consecutive heartbeats without spatial or temporal gaps using a wide-detector CT, and redistributed into 11 series of single-phase CTP acquired from -2 s to 8 s from the time of maximal enhancement (Tmax) in the ascending aorta...
October 28, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/27793158/clinical-and-echocardiographic-predictors-of-mortality-in-acute-pulmonary-embolism
#12
Talal Dahhan, Irfan Siddiqui, Victor F Tapson, Eric J Velazquez, Stephanie Sun, Clemontina A Davenport, Zainab Samad, Sudarshan Rajagopal
PURPOSE: The aim of this study was to evaluate the utility of adding quantitative assessments of cardiac function from echocardiography to clinical factors in predicting the outcome of patients with acute pulmonary embolism (PE). METHODS: Patients with a diagnosis of acute PE, based on a positive ventilation perfusion scan or computed tomography (CT) chest angiogram, were identified using the Duke University Hospital Database. Of these, 69 had echocardiograms within 24-48 h of the diagnosis that were suitable for offline analysis...
October 28, 2016: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/27718140/prediction-of-clinical-outcome-by-myocardial-ct-perfusion-in-patients-with-low-risk-unstable-angina-pectoris
#13
Jesper J Linde, Mathias Sørgaard, Jørgen T Kühl, Jens D Hove, Henning Kelbæk, Walter B Nielsen, Klaus F Kofoed
The prognostic implications of myocardial computed tomography perfusion (CTP) analyses are unknown. In this sub-study to the CATCH-trial we evaluate the ability of adenosine stress CTP findings to predict mid-term major adverse cardiac events (MACE). In 240 patients with acute-onset chest pain, yet normal electrocardiograms and troponins, a clinically blinded adenosine stress CTP scan was performed in addition to conventional diagnostic evaluation. A reversible perfusion defect (PD) was found in 38 patients (16 %) and during a median follow-up of 19 months (range 12-22 months) 25 patients (10 %) suffered a MACE (cardiac death, non-fatal myocardial infarction and revascularizations)...
October 7, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27698722/analysis-of-the-first-therapeutic-target-achieving-time-of-warfarin-therapy-and-associated-factors-in-patients-with-pulmonary-embolism
#14
Xiaowei Gong, Haiyan Wang, Yadong Yuan
The present study aimed to investigate the factors affecting the first therapeutic-target-achieving (TTA) time of warfarin therapy in patients with acute pulmonary embolism (PTE). Between January 2008 and June 2013, patients with PTE confirmed by transpulmonary arterial enhanced computed tomographic pulmonary angiography or pulmonary ventilation perfusion scanning were included in the present study. Data collected included demographic information, history of tobacco and alcohol intake, basic diseases (stable and unstable hypertension, diabetes, heart failure, cancer/cerebral infarction, old myocardial infarction and atrial fibrillation), liver and kidney function, the haemoglobin and platelet count of the blood, international normalized ratio monitoring, warfarin dosage adjustment and medication combinations...
October 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27651740/comparison-of-hemodynamic-effects-and-negative-predictive-value-of-normal-adenosine-gated-myocardial-perfusion-scan-with-or-without-caffeine-abstinence
#15
Maseeh Uz Zaman, Nosheen Fatima, Areeba Zaman, Unaiza Zaman, Rabia Tahseen
For vasodilator stress, myocardial perfusion imaging (MPI) with at least 12-h caffeine abstinence is recommended, as it attenuates cardiovascular hyperemic response of adenosine and dipyridamole. However, many published conflicting results have shown no significant effect upon perfusion abnormalities in MPI performed without caffeine abstinence. The aim of this study was to compare the hemodynamic changes and negative predictive value (NPV) of normal MPIs with adenosine stress performed with or without caffeine abstinence...
September 2016: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/27605488/an-empirical-method-for-reducing-variability-and-complexity-of-myocardial-perfusion-quantification-by-dual-bolus-cardiac-mri
#16
Neil Chatterjee, Brandon C Benefield, Kathleen R Harris, Jacob U Fluckiger, Timothy Carroll, Daniel C Lee
PURPOSE: Myocardial perfusion can be quantified using the "dual bolus" technique, which uses two separate contrast boluses to avoid signal nonlinearity in the blood pool. This technique relies on knowing the precise ratio of contrast concentrations between the two boluses. In this study, we investigated the variability found in these ratios, as well as the error it introduces, and developed a method for correction. METHODS: Five dogs received dual bolus myocardial perfusion MRI scans...
September 8, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27604183/a-look-locker-acquisition-scheme-for-quantitative-myocardial-perfusion-imaging-with-fair-arterial-spin-labeling-in-humans-at-3-tesla
#17
Graeme A Keith, Christopher T Rodgers, Michael A Chappell, Matthew D Robson
PURPOSE: A novel method for quantitative measurement of myocardial blood flow (MBF) using arterial spin labeling (ASL) in a single breath-hold is presented, evaluated by simulations, phantom studies and in vivo studies and tested for reproducibility and variability. METHODS: A flow-sensitive alternating inversion recovery (FAIR) ASL method with Look-Locker readout (LL-FAIR-ASL) was implemented at 3 tesla. Scans were performed on 10 healthy volunteers and MBF measured in three slices...
September 8, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27595687/myocardial-perfusion-320-row-multidetector-computed-tomography-guided-treatment-strategy-for-the-clinical-management-of-patients-with-recent-acute-onset-chest-pain-design-of-the-cardiac-ct-in-the-treatment-of-acute-chest-pain-catch-2-randomized-controlled-trial
#18
Mathias Sørgaard, Jesper J Linde, Jens D Hove, Jan R Petersen, Tem B S Jørgensen, Jawdat Abdulla, Merete Heitmann, Charlotte Kragelund, Thomas Fritz Hansen, Patricia M Udholm, Christian Pihl, J Tobias Kühl, Thomas Engstrøm, Jan Skov Jensen, Dan E Høfsten, Henning Kelbæk, Klaus F Kofoed
AIMS: Patients admitted with chest pain are a diagnostic challenge because the majority does not have coronary artery disease (CAD). Assessment of CAD with coronary computed tomography angiography (CCTA) is safe, cost-effective, and accurate, albeit with a modest specificity. Stress myocardial computed tomography perfusion (CTP) has been shown to increase the specificity when added to CCTA, without lowering the sensitivity. This article describes the design of a randomized controlled trial, CATCH-2, comparing a clinical diagnostic management strategy of CCTA alone against CCTA in combination with CTP...
September 2016: American Heart Journal
https://www.readbyqxmd.com/read/27587054/noise-suppressed-partial-volume-correction-for-cardiac-spect-ct
#19
Chung Chan, Hui Liu, Yariv Grobshtein, Mitchel R Stacy, Albert J Sinusas, Chi Liu
PURPOSE: Partial volume correction (PVC) methods typically improve quantification at the expense of increased image noise and reduced reproducibility. In this study, the authors developed a novel voxel-based PVC method that incorporates anatomical knowledge to improve quantification while suppressing noise for cardiac SPECT/CT imaging. METHODS: In the proposed method, the SPECT images were first reconstructed using anatomical-based maximum a posteriori (AMAP) with Bowsher's prior to penalize noise while preserving boundaries...
September 2016: Medical Physics
https://www.readbyqxmd.com/read/27577514/did-low-tube-voltage-ct-combined-with-low-contrast-media-burden-protocols-accomplish-the-goal-of-double-low-for-patients-an-overview-of-applications-in-vessels-and-abdominal-parenchymal-organs-over-the-past-5%C3%A2-years
#20
REVIEW
Yaqi Shen, Xuemei Hu, Xianlun Zou, Di Zhu, Zhen Li, Daoyu Hu
BACKGROUND: Imaging communities have already reached a consensus that the radiation dose of computed tomography (CT) should be reduced as much as reasonably achievable to lower population risks. Increasing attention is being paid to iodinated contrast media (CM) induced nephrotoxicity (CIN); a decrease in the intake of iodinated CM is required by increasingly more radiologists. Theoretically, the radiation dose varies with the tube current time and square of the tube voltage, with higher iodine contrast at low photon energies (Huda et al...
September 2016: International Journal of Clinical Practice
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