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https://www.readbyqxmd.com/read/27867904/incremental-role-of-18-f-fluorocholine-pet-ct-over-technetium-99m-labeled-mibi-scan-in-hyperparathyroidism
#1
Abhishek Behera, Nishikant Avinash Damle
No abstract text is available yet for this article.
November 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27857527/primary-hyperparathyroidism-jaw-tumor-syndrome-a-confusing-and-forgotten-diagnosis
#2
Doina Piciu, Andra Piciu, Elena Barbus, Claudiu Pestean, Maria Iulia Larg, Bogdan Fetica
BACKGROUND: Primary hyperparathyroidism is caused by the excessive growth of parathormone secretion, its consequence being hypercalcemia. The parathyroid adenoma is responsible for over half of primary hyperparathyroidism cases. The mandibular tumor can be the initial sign in the case of primary hyperparathyroidism. CASE PRESENTATION: We present the case of a 33 year old patient with history of a mandibular operated tumor, repetitive pathological fractures and hypercalcemia manifestations...
2016: Clujul Medical (1957)
https://www.readbyqxmd.com/read/27846041/factors-affecting-the-sensitivity-of-tc-99m-methoxyisobutylisonitrile-dual-phase-parathyroid-single-photon-emission-computed-tomography-in-primary-hyperparathyroidism
#3
Mine Araz, Derya Çayir, Mehmet Erdoğan, Bekir Uçan, Erman Çakal
OBJECTIVE: The aim of this study was to investigate the effects of thyroid diseases and regularly used medications on the sensitivity of Tc-99m methoxyisobutylisonitrile (MIBI) dual-phase parathyroid single photon emission computed tomography (SPECT) and to define indicatives of the result of the study. PATIENTS AND METHODS: Overall, 218 primary hyperparathyroidism patients (190 women, 28 men, mean age: 57±14 years) with thyroid-parathyroid ultrasonography and Tc-99m MIBI dual-phase parathyroid SPECT were retrospectively enrolled...
November 11, 2016: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/27834016/is-c-11-methionine-pet-ct-able-to-localise-sestamibi-negative-parathyroid-adenomas
#4
Theresia Weber, Martin Gottstein, Sabrina Schwenzer, Ambros Beer, Markus Luster
BACKGROUND: Patients with primary hyperparathyroidism (pHPT) and a negative preoperative Tc-99 sestamibi (MIBI) scintigraphy are considered to have a higher risk of persistent disease. The aim of this study was to assess whether additional imaging with C-11 methionine positron emission tomography/computed tomography (Met-PET/CT) is able to localise sestamibi-negative hyperfunctioning parathyroid glands. METHODS: In 50 patients (38 females, 12 males, age 13-81 years) with pHPT and negative localisation procedures such as ultrasound and sestamibi, a Met-PET/CT was performed before parathyroid surgery...
November 10, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27829657/reprising-ramadan-related-angina-pectoris-a-potential-strategy-for-risk-reduction
#5
Arthur J Siegel, Nasir A Bhatti, Jason H Wasfy
BACKGROUND A preponderance of evidence supports short-term aspirin usage to reduce transiently increased cardiovascular risk in clinical conditions that promote acute myocardial ischemia. CASE REPORT We report on the case of a 69-year-old male of Muslim Indian heritage with multiple cardiovascular risk factors who experienced the onset of angina pectoris while fasting for Ramadan for more than 16 hours daily for 30 days in July 2015. While symptom free for 2 months on medical management after ending his fast, he underwent quadruple coronary artery bypass surgery for severe 4-vessel disease following an acute anterior myocardial infarction...
November 10, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27813617/semi-quantitative-method-for-the-assessment-of-focal-lesions-in-parathyroid-scintigraphy-with-relation-to-histopathology-a-prospective-study
#6
Maria Henryka Listewnik, Hanna Piwowarska-Bilska, Mirela Kurantowicz, Marek Ostrowski, Andrzej Borowiecki, Krzysztof Safranow, Krystyna Jasiakiewicz, Jacek Iwanowski, Maria Chosia, Maria Laszczyńska, Bożena Birkenfeld
BACKGROUND: The aim of this paper was to analyse our own semi-quantitative method of assessing focal lesions localised in pre-operative diagnostic scintigraphy of primary hyperparathyroidism (PHPT) using 99mTc-MIBI with washout and comparing these data with the result of the histopathological examination (HP). MATERIAL AND METHODS: A total of 40 (37 female, 3 male, average age 58.7 years) patients with a suspicion of PHPT were enrolled for prospective analysis. Dual phase planar and SPECT/CT examination with 99mTc-MIBI were performed...
November 4, 2016: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/27812061/a-new-technique-to-simplify-the-minimally-invasive-parathyroidectomy-ultrasound-assisted-guided-wire-localization-for-solitary-parathyroid-adenomas
#7
Faruk Ozkul, Muhammed Kasim Arik, Mustafa Eroglu, Umut Faydaci, Huseyin Toman, Sukru Tas, Kubilay Ukinc, Mehmet Asik
OBJECTIVE: To investigate the benefits of ultrasound-assisted guided wire localization in MIP for selected cases. METHODS: In this prospective, nonrandomised study, we included 36 patients with solitary parathyroid adenomas diagnosed preoperatively by 99m Tc sesta MIBI scintigraphy and/or neck ultrasonography. An ultrasound-guided wire was placed in the solitary parathyroid adenoma preoperatively. MIPs were performed under local anaesthesia plus sedation. After the excision, the parathyroidectomy was confirmed with postoperative ultrasonography...
November 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27749776/reverse-perfusion-pattern-in-myocardial-perfusion-imaging-using-technetium-99m-sestamibi-in-patients-with-intermediate-risk-for-coronary-artery-disease-in-relation-to-the-time-of-acquisition-and-intensity-of-visceral-uptake-as-artifactual-causes
#8
Babak Fallahi, Davood Beiki, Yalda Salehi, Alireza Emami-Ardekani, Armaghan Fard-Esfahani, Farahnaz Aghahosseini, Mahdi Haghighatafshar, Mohammad Eftekhari
OBJECTIVE: With respect to the equivocal value of the reverse perfusion pattern (RPP) in technetium-99m (Tc)-sestamibi myocardial perfusion imaging, a study was carried out to evaluate this pattern in association with the presence or absence of coronary artery disease (CAD) and other underlying factors, mainly the time of acquisition and the presence of intense visceral uptake. PATIENTS AND METHODS: We prospectively studied 102 patients with a moderate risk of CAD (41 men and 61 women, mean age: 56...
January 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/27746124/in-vitro-evaluation-of-pyrethroid-mediated-changes-on-neuronal-burst-parameters-using-microelectrode-arrays
#9
Baskar Mohana Krishnan, Balakrishna Murthy Prakhya
Effects of pyrethroids (beta-cyfluthrin, bifenthrin, cypermethrin, deltamethrin, lambda-cyhalothrin, and permethrin) on the burst parameters (mean burst rate [MBR], percent spikes in burst [PSB], mean burst duration [MBD], mean spikes in burst [MSB], mean interspike interval in burst [MISIB], and mean interburst interval [MIBI]) have been investigated using the microelectrode array technique. Rat cortical neuronal networks (between 24 and 35 DIV) were exposed to the five accumulative concentrations of pyrethroids (0...
October 13, 2016: Neurotoxicology
https://www.readbyqxmd.com/read/27734796/the-coexistence-of-primary-hyperparathyroidism-and-thyroid-nodules-should-the-preoperative-work-up-of-the-parathyroid-and-the-thyroid-diseases-be-specifically-adjusted
#10
G Scerrino, M Attard, C Lo Piccolo, A Attard, G I Melfa, C Raspanti, M Zarcone, S Bonventre, S Mazzola, G Gulotta
INTRODUCTION AND OBJECTIVES: Primary hyperparathyroidism (PHPT) can be found in concomitance with thyroid disease (TD) in a high frequency of cases. In this context the diagnostic exams for localizing the enlarged parathyroid(s) gland(s) could be less reliable or nonconclusive. Moreover, the thyroid carcinoma seems to be more frequent compared to that isolated thyroid desease and, therefore, carefully investigated. The main goal of the present study is to evaluate which diagnostic tool (US, MIBI) is more reliable for localizing the site of the PTH hypersecretion and to confirm if it is always advantageous a combination of both exams...
May 2016: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/27730071/impact-of-preoperative-imaging-on-surgical-approach-for-primary-hyperparathyroidism-data-from-single-institution-in-india
#11
Parjeet Kaur, Raghav Gattani, Alka Ashmita Singhal, Deepak Sarin, Sowrabh Kumar Arora, Ambrish Mithal
CONTEXT: Preoperative localization of parathyroid adenoma is essential in deciding the surgical approach of parathyroidectomy. AIM: To describe clinical and biochemical profile, evaluate preoperative imaging modalities and surgical approach in patients with primary hyperparathyroidism (PHPT). METHODOLOGY: This was a retrospective study conducted at the single institution. All patients who underwent evaluation and surgery for PHPT from 2011 to 2015 were included in the study...
September 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27726929/contribution-of-18-fdg-pet-ct-to-brown-tumor-detection-in-a-patient-with-primary-hyperparathyroidism
#12
Mélanie Gahier Penhoat, Delphine Drui, Catherine Ansquer, Eric Mirallie, Yves Maugars, Pascale Guillot
We report the case of a patient who presented with multiple brown tumors as the inaugural manifestation of primary hyperparathyroidism. Tc-99m hexakis methoxyisobutylisonitrile (99mTc-MIBI) scintigraphy demonstrated increased radiotracer uptake by the bone lesions. The patient was a 65-year-old male who sought advice for a swelling on his right shin. An osteolytic lesion was visible on the radiograph. A bone biopsy showed a benign tumor containing abundant osteoclastic cells. Laboratory abnormalities included hypercalcemia (3...
October 7, 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/27723623/-left-ventricular-dyssynchrony-in-prolonged-septal-stimulation
#13
Federico Ferrando-Castagnetto, Roberto Ricca-Mallada, Alejandro Vidal, Fabián Martínez, Rodolfo Ferrando
Pacemaker stimulation is associated with unpredictable severe cardiac events. We evaluated left ventricular mechanical dyssynchrony (LVMD) during prolonged septal right ventricular pacing. We performed 99mTc-MIBI gated-SPECT and phase analysis in 6 patients with pacemakers implanted at least one year before scintigraphy due to advanced atrioventricular block. Using V-Sync of Emory Cardiac Toolbox we obtained phase bandwidth (PBW) and standard deviation (PSD) from rest phase histogram. Clinical variables, QRS duration, rate and mode of pacing in septal right ventricle wall, chamber diameters, presence and extension of myocardial scar and ischemia and rest LVEF were recorded...
2016: Medicina
https://www.readbyqxmd.com/read/27704321/preoperative-99m-tc-mibi-spect-ct-interpretation-criteria-for-localization-of-parathyroid-adenomas-correlation-with-surgical-findings
#14
Zohar Keidar, Elena Solomonov, Rachel Karry, Alex Frenkel, Ora Israel, Michal Mekel
PURPOSE: Minimally invasive surgery for parathyroid adenomas (PTA) requires precise identification and localization of the diseased gland prior to exploration for optimal surgical planning. The Perrier classification allows for accurate, reproducible, and reliable description of PTA location and communication of clinically significant information to surgeons. The current study compares the Perrier localization of PTA on [(99m)Tc]methoxyisobutylisonitrile ([(99m)Tc]MIBI) single-photon emission computed tomography (SPECT)/X-ray computed tomography (CT) with the results of surgery...
October 4, 2016: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/27663723/coronary-artery-bypass-grafting-and-percutaneous-coronary-intervention-after-kawasaki-disease-the-pediatric-canadian-series
#15
A Dionne, M Bakloul, C Manlhiot, B W McCrindle, M Hosking, C Houde, D Pepelassis, N Dahdah
Coronary artery (CA) aneurysms are serious complications of Kawasaki disease (KD) responsible for ischemic events. Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are reported with limited data on indications and comparative efficacy. Retrospective multicenter comparison of CA intervention following KD is performed in this study. Twenty two cases were available from 5 centers, of whom 11 underwent CABG, 10 PCI and 1 systemic thrombolysis. Age at intervention (8.3 ± 3.9 vs 11...
September 23, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27651740/comparison-of-hemodynamic-effects-and-negative-predictive-value-of-normal-adenosine-gated-myocardial-perfusion-scan-with-or-without-caffeine-abstinence
#16
Maseeh Uz Zaman, Nosheen Fatima, Areeba Zaman, Unaiza Zaman, Rabia Tahseen
For vasodilator stress, myocardial perfusion imaging (MPI) with at least 12-h caffeine abstinence is recommended, as it attenuates cardiovascular hyperemic response of adenosine and dipyridamole. However, many published conflicting results have shown no significant effect upon perfusion abnormalities in MPI performed without caffeine abstinence. The aim of this study was to compare the hemodynamic changes and negative predictive value (NPV) of normal MPIs with adenosine stress performed with or without caffeine abstinence...
September 2016: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/27609978/specific-immune-cell-and-cytokine-characteristics-of-human-testicular-germ-cell-neoplasia
#17
Britta Klein, Thomas Haggeney, Daniela Fietz, Sivanjah Indumathy, Kate L Loveland, Mark Hedger, Sabine Kliesch, Wolfgang Weidner, Martin Bergmann, Hans-Christian Schuppe
STUDY QUESTION: Which immune cells and cytokine profiles are characteristic for testicular germ cell neoplasia and what consequences does this have for the understanding of the related testicular immunopathology? SUMMARY ANSWER: The unique immune environment of testicular germ cell neoplasia comprises B cells and dendritic cells as well as high transcript levels of IL-6 and other B cell supporting or T helper cell type 1 (Th1)-driven cytokines and thus differs profoundly from normal testis or inflammatory lesions associated with hypospermatogenesis...
October 2016: Human Reproduction
https://www.readbyqxmd.com/read/27589877/the-diagnostic-value-of-11c-methionine-pet-in-hyperparathyroidism-with-negative-99mtc-mibi-spect-a-meta-analysis
#18
Leilei Yuan, Jun Liu, Ying Kan, Jigang Yang, Xufu Wang
BACKGROUND: 99mTc-sestamibi (MIBI) parathyroid SPECT is generally regarded as the best preoperative localizing method in patients with hyperparathyroidism (HPT). However, 99mTc-MIBI SPECT is false negative in approximately 25% of adenomas. 11C-methionine positron emission tomography (PET) has been used in HPT with negative 99mTc-MIBI SPECT scan results. PURPOSE: To systematically review and conduct a meta-analysis of published data on the performance of 11C-methionine PET in patients with HPT with negative 99mTc-MIBI SPECT...
September 2, 2016: Acta Radiologica
https://www.readbyqxmd.com/read/27585576/spect-myocardial-blood-flow-quantitation-toward-clinical-use-a-comparative-study-with-13-n-ammonia-pet-myocardial-blood-flow-quantitation
#19
Bailing Hsu, Lien-Hsin Hu, Bang-Hung Yang, Lung-Ching Chen, Yen-Kung Chen, Chien-Hsin Ting, Guang-Uei Hung, Wen-Sheng Huang, Tao-Cheng Wu
OBJECTIVES: The aim of this study was to evaluate the accuracy of myocardial blood flow (MBF) quantitation of (99m)Tc-Sestamibi (MIBI) single photon emission computed tomography (SPECT) compared with (13)N-Ammonia (NH3) position emission tomography (PET) on the same cohorts. BACKGROUND: Recent advances of SPECT technologies have been applied to develop MBF quantitation as a promising tool to diagnose coronary artery disease (CAD) for areas where PET MBF quantitation is not available...
September 1, 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27557453/cost-benefit-analysis-of-the-intraoperative-parathyroid-hormone-assay-in-primary-hyperparathyroidism
#20
Benedetta Badii, Fabio Staderini, Caterina Foppa, Lorenzo Tofani, Ileana Skalamera, Giulia Fiorenza, Eva Qirici, Fabio Cianchi, Giuliano Perigli
BACKGROUND: The purpose of this study was to evaluate the usefulness of the routine intraoperative intact parathyroid hormone (IOPTH) assay, the role of unilateral and bilateral cervical exploration and of preoperative imaging, and to do a cost-benefit analysis in parathyroidectomy for primary hyperparathyroidism. METHODS: Two hundred sixty-four patients who underwent operations between January 2000 and March 2015 were retrospectively divided into 2 groups. RESULTS: Group A (IOPTH) was composed of 64 patients...
August 24, 2016: Head & Neck
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