keyword
MENU ▼
Read by QxMD icon Read
search

albendazol

keyword
https://www.readbyqxmd.com/read/28644256/cluster-like-headache-secondary-to-focal-cervical-myelitis
#1
Dong-Eun Kim, Ji-Yun Park, Hyeonuk Ha, Geum-Jin Yoon, Bang-Hoon Cho, Seung-Han Lee
BACKGROUND: Cluster headache (CH) is characterized by attacks of severe periorbital pain associated with autonomic symptoms. As with other forms of primary headache, structural lesions should be excluded, particularly if the headache presents with an atypical pattern. CASE: We report a 41-year-old woman who had no previous history of primary headache and showed a poor response to medication for CH. The patient was finally diagnosed as secondary headache with CH feature due to focal myelitis at the cervical level of the spinal cord...
July 2017: Neurologist
https://www.readbyqxmd.com/read/28632749/using-a-health-rating-system-to-evaluate-the-usefulness-of-caenorhabditis-elegans-as-a-model-for-anthelmintic-study
#2
Kathryn J Weaver, Cassandra J May, Brian L Ellis
Soil-transmitted helminths (STHs) are intestinal parasitic nematodes that infect humans, and are transmitted through contaminated soil. These nematodes include the large roundworm (Ascaris lumbricoides), whipworm (Trichuris trichiura), and hookworm (Ancylostoma ceylanicum, Ancylostoma duodenale, and Necator americanus). Nearly 1.5 billion people (~24% of the population) worldwide are infected with at least one species of these parasites, burdening the poor, in particular, children and pregnant women. To combat these diseases, the WHO only recognizes four anthelmintic drugs, including the preferred drug, albendazole, for mass drug administration (MDA)...
2017: PloS One
https://www.readbyqxmd.com/read/28630586/surveillance-efforts-after-mass-drug-administration-to-validate-elimination-of-lymphatic-filariasis-as-a-public-health-problem-in-vanuatu
#3
Fasihah Taleo, George Taleo, Patricia M Graves, Peter Wood, Sung Hye Kim, Masayo Ozaki, Hayley Joseph, Brian Chu, Alex Pavluck, Aya Yajima, Wayne Melrose, Kazuyo Ichimori, Corinne Capuano
BACKGROUND: Vanuatu was formerly highly endemic for lymphatic filariasis (LF), caused by Wuchereria bancrofti and transmitted by Anopheles mosquitoes. After a baseline survey showing 4.8% antigen prevalence in 1998, the country conducted nationwide (in one implementation unit) annual mass drug administration (MDA) with albendazole and diethylcarbamazine citrate from 2000 to 2004 and achieved prevalence of 0.2% by 2006 in a representative nationwide cluster survey among all age groups...
2017: Tropical Medicine and Health
https://www.readbyqxmd.com/read/28618740/screening-of-immunocompromised-patients-at-risk-of-strongyloidiasis-in-western-turkey-using-elisa-and-real-time-pcr
#4
Esra Erdem Kivrak, Esra Atalay Şahar, Hüseyin Can, Mert Döşkaya, Mümtaz Yilmaz, Hüsnü Pullukçu, Ayşe Caner, Hüseyin Töz, Adnan Yüksel Gürüz, Meltem Işikgöz Taşbakan
BACKGROUND/AIM: Strongyloides stercoralis causes life-threatening hyperinfection or disseminated strongyloidiasis in immunocompromised patients such as HIV-positive, organ transplantation, and cancer patients. This study investigated the presence of strongyloidiasis in immunocompromised patients for the first time in Turkey. MATERIALS AND METHODS: Serum and stool samples were collected from 108 patients (25.9% of them were chronic renal failure and 74.1% were renal transplantation patients) who were admitted to Ege University Medical School in İzmir, located in western Turkey...
June 12, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28596826/field-evaluation-of-the-efficacy-of-common-anthelmintics-used-in-the-control-of-gastrointestinal-nematodes-of-sheep-in-dabat-district-northwest-ethiopia
#5
Zewdu Seyoum, Yitayew Demessie, Basazinew Bogale, Achenef Melaku
BACKGROUND: Gastrointestinal nematode (GIN) infections are the main impediments that restrict the welfare and productivity of small ruminant in the world. Effective management of GINs in grazing sheep relies heavily on the use of highly efficacious anthelmintic drugs. However, anthelmintic resistance is becoming a significant concern in the world, and this phenomenon severely threatens the potential utilisation of this control strategy. Therefore, this study was conducted 1) to evaluate the efficacy of commonly used anthelmintic on GINs in naturally infected sheep and 2) to assess the farmers' perception on anthelmintics utilisation practices in Dabat district, Northwest Ethiopia...
2017: Irish Veterinary Journal
https://www.readbyqxmd.com/read/28595066/synthesis-antiprotozoal-activity-and-chemoinformatic-analysis-of-2-methylthio-1h-benzimidazole-5-carboxamide-derivatives-identification-of-new-selective-giardicidal-and-trichomonicidal-compounds
#6
Paulina Flores-Carrillo, José Miguel Velázquez-López, Rodrigo Aguayo-Ortiz, Alicia Hernández-Campos, Pedro Josué Trejo-Soto, Lilián Yépez-Mulia, Rafael Castillo
A series of twelve new 2-(methylthio)-1H-benzimidazole-5-carboxamide derivatives (1-12) were synthesized and their antiparasitic activity was tested in vitro against Giardia intestinalis, Trichomonas vaginalis and Entamoeba histolytica. Experimental evaluations showed IC50 values within the nanomolar range for all tested compounds, some showing higher activity than metronidazole and albendazole. A chemoinformatic study was used to compare the structure-activity relationship of the synthesized carboxamides with those of 91 previously studied benzimidazoles, and with some Nitazoxanide-N-methylbenzimidazole hybrids recently synthetized by our group...
May 29, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28588763/proof-of-concept-of-faecal-egg-nematode-counting-as-a-practical-means-of-veterinary-engagement-with-planned-livestock-health-management-in-a-lower-income-country
#7
Eithne Leahy, Barend Bronsvoort, Luke Gamble, Andrew Gibson, Henderson Kaponda, Dagmar Mayer, Stella Mazeri, Kate Shervell, Neil Sargison
BACKGROUND: The wellbeing and livelihood of farmers in impoverished regions of the world is intrinsically linked to the health and welfare of their livestock; hence improved animal health is a pragmatic component of poverty alleviation. Prerequisite knowledge and understanding of the animal health challenges facing cattle keepers in Malawi is constrained by the lack of veterinary infrastructure, which inevitably accompanies under-resourced rural development in a poor country. METHODS: We collaborated with public and private paraveterinary services to locate 62 village Zebu calves and 60 dairy co-operative calves dispersed over a wide geographical area...
2017: Irish Veterinary Journal
https://www.readbyqxmd.com/read/28575043/radiological-evolution-of-porcine-neurocysticercosis-after-combined-antiparasitic-treatment-with-praziquantel-and-albendazole
#8
Carla Cangalaya, Javier A Bustos, Juan Calcina, Ana Vargas-Calla, Javier Mamani, Diego Suarez, Gianfranco Arroyo, Armando E Gonzalez, Juan Chacaltana, Cristina Guerra-Giraldez, Siddhartha Mahanty, Theodore E Nash, Héctor H García
BACKGROUND: The onset of anthelmintic treatment of neurocysticercosis (NCC) provokes an acute immune response of the host, which in human cases is associated with exacerbation of neurological symptoms. This inflammation can occur at the first days of therapy. So, changes in the brain cysts appearance may be detected by medical imaging. We evaluated radiological changes in the appearance of brain cysts (enhancement and size) on days two and five after the onset of antiparasitic treatment using naturally infected pigs as a model for human NCC...
June 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28558679/demonstration-of-biological-activities-of-extracts-from-isodon-rugosus-wall-ex-benth-separation-and-identification-of-bioactive-phytoconstituents-by-gc-ms-analysis-in-the-ethyl-acetate-extract
#9
Anwar Zeb, Farhat Ullah, Muhammad Ayaz, Sajjad Ahmad, Abdul Sadiq
BACKGROUND: Since long, natural sources have been explored for possible managements of various diseases. In this context, the study is designed to evaluate Isodon rugosus Wall. ex Benth for biological potentials including antibacterial, anthelmintic, insecticidal, anti-termites and anti-Pharaoh activities followed by GC-MS analysis of active fraction to identify various bioactive compounds. METHODS: I. rugosus was investigated against eight bacterial strains using well diffusion method and microdilution method with ceftriaxone as positive control...
May 30, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28553397/solitary-intramedullary-cervical-cysticercosis-without-neurological-deficit-a-rare-case-report
#10
Rahul Ranjan, Tulika, Suresh Chand, Akhil Agnihotri
Neurocysticercosis is commonly seen intracranially and its incidence in the spinal cord is very low. Among spine dorsal region is more common due to more blood flow in this region and it is usually associated with lesion at other sites. The intramedullary location is rarer than extramedullary. Hence, solitary intramedullary cervical spine cysticercosis (ICC) is extremely rare entity. Only a handful numbers of cases are reported in the literature. All reported cases are presented with the neurological deficit as spinal canal diameter is very low and any space occupying lesion is not tolerated...
January 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28546882/in-situ-synthesis-of-a-magnetic-graphene-platform-for-the-extraction-of-benzimidazoles-from-food-samples-and-analysis-by-high-performance-liquid-chromatography
#11
Qianchun Zhang, Yulan Liu, Xingyi Wang, Huimin Li, Junyu Chen
A novel method was proposed for the determination of five benzimidazoles (oxfendazole, mebendazole, flubendazole, albendazole, and fenbendazole) using magnetic graphene (G-Fe3O4). G-Fe3O4 was synthesized via in situ chemical coprecipitation. The properties of G-Fe3O4 were characterized by various instrumental methods. G-Fe3O4 exhibited a great adsorption ability and good stability towards analytes. Various experimental parameters that might affect the extraction efficiency such as the amount of G-Fe3O4, extraction solvent, extraction time, and desorption conditions were evaluated...
2017: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/28542546/albendazole-increases-the-inflammatory-response-and-the-amount-of-em2-positive-small-particles-of-echinococcus-multilocularis-spems-in-human-hepatic-alveolar-echinococcosis-lesions
#12
Franz J Ricken, Juliane Nell, Beate Grüner, Julian Schmidberger, Tanja Kaltenbach, Wolfgang Kratzer, Andreas Hillenbrand, Doris Henne-Bruns, Peter Deplazes, Peter Moller, Peter Kern, Thomas F E Barth
BACKGROUND: Alveolar echinococcosis (AE) is caused by the metacestode stage of Echinococcus multilocularis. The inflammatory response to this infection is influenced by the interaction of the parasite with the host. We aimed to analyze human liver lesions infected with Echinococcus multilocularis and the changes of the cellular infiltrates during albendazole (ABZ) treatment. METHODOLOGY/PRINCIPAL FINDINGS: We analyzed liver tissue samples from 8 untreated patients, 5 patients treated with two daily doses of 400 mg ABZ for up to two months and 7 patients treated for more than two months with the same ABZ therapy...
May 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28538856/-an-adolescent-with-lumbosacral-instability-due-to-the-presence-of-a-hydatid-cyst-a-case-report
#13
Miguel Vizcarra, Mijaíl Mujica, Vladimir Sánchez, Paul Méndez
Hydatidosis, caused by Echinococcus granulosus, affects the spinal column in 0.5-2% of all cases, with the sacral column being a rare location typically observed only in adults. The case is reported of a 14-year-old boy from Juliaca (Puno, Peru) who presented with chronic lower back pain and cauda equina syndrome. He was initially attended to in Juliaca, and then transferred to the Hospital Edgardo Rebagliati Martins (Lima, Peru) with a diagnosis of sacral tumor. In magnetic resonance imaging, a multicystic tumor was seen with L5 and S1 lysis and instability...
January 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28533856/-hydatid-cyst-of-the-posterior-fossa
#14
Abderrazzak El Saqui, Mohamed Aggouri, Mohamed Benzagmout, Khaled Chakour, Mohamed El Faizchaoui
Hydatidosis is an endemic affection in Morocco. Cerebral echinococcosis is a relatively rare entity accounting for only 1-2% of all hydatid cysts in humans. hydatid cyst of the posterior fossa is a very uncommon site for the disease. We report the case of a 12 year-old child admitted for high intracranial pressure. Brain CT scan showed a posterior fossa cyst without enhancement after contrast medium injection. Operative finding revealed a hydatid cyst. The histological examination of the tissue sample confirmed the diagnosis...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28529602/super-aqueous-solubility-of-albendazole-in-%C3%AE-cyclodextrin-for-parenteral-application-in-cancer-therapy
#15
Krishna Pillai, Javed Akhter, David Lawson Morris
Poor aqueous solubility of anticancer drug, albendazole (ABZ), prevents parenteral application. Here, we demonstrate how to increase the aqueous solubility of ABZ to 6- 8 mg/ml using sulfobutylether - β-cyclodextrin (SBE-β-CD) or Hydroxypropyl- β-cyclodextrin (HP- β-CD) by manipulation of complexation parameters such as the physical state of ABZ (ionized in acetic acid), the concentration of ionised ABZ, agitation time and temperature. Solubility was first examined with suspension of excess ABZ powder in cyclodextrin (CD) solutions at pH (2...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28489921/time-trend-of-neurocysticercosis-in-children-with-seizures-in-a-tertiary-hospital-of-western-nepal
#16
Kalipatnam Seshagiri Rao, Sudhir Adhikari, Eva Gauchan, Brijesh Sathian, Ganesh B K, Sahisnuta Basnet, Prabhat Kumar Tiwari, Namraj Bahadur, Rajnish Mishra
INTRODUCTION: Neurocysticercosis is a common cause of seizure disorders in children of Western Nepal. The clinical presentation is variable. The incidence varies depending on the food habits and ethnicity of the population. The present study was undertaken with the objective of studying the mode of presentation, radiological findings and to determine the recent trend of the disease in children of Western Nepal. METHODS: Records from the Department of Pediatrics, Manipal Teaching Hospital, Pokhara, Nepal of children aged 0-17 years admitted from 2003 to 2015 and with the discharge diagnosis of seizure and neurocysticercosis (NCC) were reviewed...
May 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28488581/repurposing-albendazole-new-potential-as-a-chemotherapeutic-agent-with-preferential-activity-against-hpv-negative-head-and-neck-squamous-cell-cancer
#17
Farhad Ghasemi, Morgan Black, Frederick Vizeacoumar, Nicole Pinto, Kara M Ruicci, Carson Cao Son Huu Le, Matthew R Lowerison, Hon Sing Leong, John Yoo, Kevin Fung, Danielle MacNeil, David A Palma, Eric Winquist, Joe S Mymryk, Paul C Boutros, Alessandro Datti, John W Barrett, Anthony C Nichols
Albendazole is an anti-helminthic drug that has been shown to exhibit anti-cancer properties, however its activity in head and neck squamous cell cancer (HNSCC) was unknown. Using a series of in vitro assays, we assessed the ability of albendazole to inhibit proliferation in 20 HNSCC cell lines across a range of albendazole doses (1 nM-10 μM). Cell lines that responded to treatment were further examined for cell death, inhibition of migration and cell cycle arrest. Thirteen of fourteen human papillomavirus-negative HNSCC cell lines responded to albendazole, with an average IC50 of 152 nM...
April 20, 2017: Oncotarget
https://www.readbyqxmd.com/read/28484563/primary-hydatid-cyst-of-pineal-region-of-brain-a-case-report-from-saudi-arabia
#18
Ahmed Bakhsh, Khalid Mukarram Ali Siddiqui, Suad Taraif
Preoperative diagnosis of cerebral echinococcosis in an unusual location is always difficult. Nonetheless, this possibility should be kept in mind in all cystic lesions of the brain. Although total excision of the cyst without rupture is a time - tested treatment, but in order to prevent recurrence, adjuvant medical treatment should also be started. Albendazole, mebenadazole and praziquental are commonly used drugs. Albendazole is a drug of choice. Its usual dose for adults is 400 mg twice daily. Exact duration of treatment is still uncertain, but it should not be <6 months...
April 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28480835/case-series-study-of-hepatic-echinococcal-cysts-in-serbia-viability-of-scolices-seropositivity-and-epidemiological-characteristics
#19
I Colovic Calovski, A Barac, Z Golubovic, A Karamarkovic, S Mitrovic, M Milicevic, M Cvetkovic, A M Dzamic
Cystic echinococcosis (CE) is an endemic helminthic disease caused by infection with Echinococcus granulosus metacestodes. Although CE is endemic in the Balkan region, the exact epidemiology remains unknown. We conducted a case-series study with the aim of evaluating the correlation between seropositivity, socio-epidemiological data, pre-operative treatment with albendazole and viability of protoscolices in human hepatic hydatid cysts. Consecutive patients with hepatic CE underwent surgery to extract E. granulosis cysts...
May 8, 2017: Journal of Helminthology
https://www.readbyqxmd.com/read/28473227/evaluating-the-predictability-of-the-in-vitro-transfer-model-and-in-vivo-rat-studies-as-a-surrogate-to-investigate-the-supersaturation-and-precipitation-behaviour-of-different-albendazole-formulations-for-humans
#20
Aaron Ruff, René Holm, Edmund S Kostewicz
The present study investigated the ability of the in vitro transfer model and an in vivo pharmacokinetic study in rats to investigate the supersaturation and precipitation behaviour of albendazole (ABZ) relative to data from a human intestinal aspiration study reported in the literature. Two lipid based formulation systems, a hydroxypropyl-β-cyclodextrin (HPβCD) solution and the addition of a crystallization inhibitor (HPMC-E5) on the behaviour of ABZ was investigated. These formulations were investigated to represent differences in their ability to facilitate supersaturation within the small intestine...
May 1, 2017: European Journal of Pharmaceutical Sciences
keyword
keyword
89718
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"