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https://www.readbyqxmd.com/read/28533692/changes-in-muscle-strength-after-diet-induced-weight-reduction-in-adult-men-with-obesity-a-prospective-study
#1
Bokun Kim, Takehiko Tsujimoto, Rina So, Xiaoguang Zhao, Sechang Oh, Kiyoji Tanaka
BACKGROUND AND OBJECTIVE: The benefits of weight reduction for musculoskeletal disorders are well understood. Steep declines in muscle mass following considerable weight reduction can decrease muscle strength and, consequently, physical performance. However, only a limited number of studies have examined the changes in muscle mass and strength in the context of interventional weight reduction programs. Thus, we investigated the influence of muscle mass decrease caused by diet-induced weight reduction on muscle strength in obese men...
2017: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/28523056/low-bone-mineral-density-in-chronic-hepatitis-b-virus-infection-a-case-control-study
#2
Zengfa Huang, Hui Wei, Cheng Cheng, Shuhua Yang, Jing Wang, Xianzhe Liu
OBJECTIVE: Osteoporosis is the well-known major complication in chronic hepatitis B virus (HBV) infection. Fewer reports are available of the relationship between bone loss and chronic HBV infection. We investigated the bone mineral density (BMD) and prevalence of osteoporosis in chronic HBV patients in comparison with healthy subjects. METHODS: We assessed 148 chronic HBV patients and 148 age- and gender-matched healthy controls by dual energy X-ray absorptiometry (DEXA) for determination of BMD...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28513264/body-composition-analysis-by-using-bioelectrical-impedance-in-a-young-healthy-chinese-population-methodological-considerations
#3
Wei Chen, Hua Jiang, Jiong-Xian Yang, Hao Yang, Jing-Min Liu, Xiu-Yuan Zhen, Lian-Jun Feng, Jian-Chun Yu
OBJECTIVE: To develop a new bioelectrical impedance analysis (BIA) model for analyzing body composition by using isotope dilution, magnetic resonance imaging (MRI), and dual-energy X-ray absorptiometry (DEXA) as the reference methods in young healthy Chinese populations. METHODS: Thirty healthy participants were enrolled. Their body composition was analyzed using BIA and 3 reference methods. We established a model that uniformed data from 3 references methods (isotope, MRI, and DEXA) into 1 formula...
June 2017: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/28512158/association-between-changes-in-fat-distribution-and-biomarkers-for-breast-cancer
#4
Willemijn A van Gemert, Evelyn Monninkhof, Anne M May, Sjoerd G Elias, Job van der Palen, Wouter Veldhuis, Maaike Stapper, Rebecca K Stellato, Jantina A Schuit, Petra H M Peeters
We assessed the associations between changes in total and abdominal fat and changes in biomarkers for breast cancer risk using data of the SHAPE-2 trial. In the SHAPE-2 trial, 243 postmenopausal overweight women were included. The intervention in this trial consisted of 5-6 kg weight loss either by diet only or exercise plus diet. After 16 weeks, we measured serum sex hormones, inflammatory markers, total body fat (measured by DEXA scan) and intra and subcutaneous abdominal fat (measured by MRI). Associations between changes in different body fat depots and biomarkers were analysed by linear regression using the study cohort irrespective of randomization in order to make maximal use of the distribution of changes in fat measures...
May 16, 2017: Endocrine-related Cancer
https://www.readbyqxmd.com/read/28500394/bed-rest-and-resistive-vibration-exercise-unveil-novel-links-between-skeletal-muscle-mitochondrial-function-and-insulin-resistance
#5
Helena C Kenny, Floriane Rudwill, Laura Breen, Michele Salanova, Dieter Blottner, Tim Heise, Martina Heer, Stephane Blanc, Donal J O'Gorman
AIMS/HYPOTHESIS: Physical inactivity has broad implications for human disease including insulin resistance, sarcopenia and obesity. The present study tested the hypothesis that (1) impaired mitochondrial respiration is linked with blunted insulin sensitivity and loss of muscle mass in healthy young men, and (2) resistive vibration exercise (RVE) would mitigate the negative metabolic effects of bed rest. METHODS: Participants (n = 9) were maintained in energy balance during 21 days of bed rest with RVE and without (CON) in a crossover study...
May 12, 2017: Diabetologia
https://www.readbyqxmd.com/read/28497942/effect-of-combined-resistance-and-endurance-exercise-training-on-regional-fat-loss
#6
Alessandro Scotto di Palumbo, Enrico Guerra, Carmine Orlandi, Ilenia Bazzucchi, Massimo Sacchetti
BACKGROUND: The present study tested the possibility of a localized fat mass (FM) reduction by means of training programmes focusing on specific bodily regions. METHODS: Sixteen physically inactive women (age: 31±4; BMI: 27.5±2.1), randomly allocated to two groups, completed an 8 week training programme. In one group (UpBdResist) training sessions consisted of upper body resistance exercises followed by 30-minute cycling at 50%VO2max, while the other group (LwBdResist) performed lower body resistance exercises followed by 30 minutes on an arm-ergometer...
June 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28496308/atorvastatin-a-double-weapon-in-osteoporosis-treatment-an-experimental-and-clinical-study
#7
Naglaa El-Nabarawi, Mohamed El-Wakd, Mostafa Salem
OBJECTIVE: The aim of this study was to evaluate the effect of atorvastatin on the bone formation and resorption markers in ovariectomized rats (experimental study), and to study its effect on the bone mineral density (BMD) in postmenopausal osteoporotic women (clinical study). MATERIALS AND METHODS: The study involved experimental and clinical aspects. In the experimental aspect, 42 female Wistar rats were divided into five groups: Group I (n=6; sham-operated), Group II (n=6; 1 mL of carboxymethyl cellulose [CMC] was administered orally), Group III (n=6; 20 mg/kg orally of atorvastatin was administered), Group IV (n=12; untreated ovariectomized [OVX] rats and served as a model of osteoporosis [OP]) and Group V (n=12; 20 mg/kg orally of atorvastatin was administered to ovariectomized rats)...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28493099/anti-inflammatory-therapeutic-effect-of-adiponectin-gene-delivery-using-a-polymeric-carrier-in-an-acute-lung-injury-model
#8
Chunxian Piao, Jeong Hyun Park, Minhyung Lee
PURPOSE: Adiponectin (APN) is an adipokine with anti-inflammatory and cytoprotective effects. In this study, the therapeutic effect of APN gene delivery using a polymeric carrier was evaluated in an acute lung injury (ALI) model. METHODS: Polyethylenimine (2 kDa, PEI2K), PEI25K (25 kDa), polyamidoamine (generation 2, PAMG2), dexamethasone-conjugated PEI2k (PEI2K-Dexa), and dexamethasone-conjugated PAMG2 (PAMG2-Dexa) were evaluated in vitro and in vivo as gene carriers...
May 10, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28490330/comparative-measurements-of-bone-mineral-density-and-bone-contrast-values-in-canine-femora-using-dual-energy-x-ray-absorptiometry-and-conventional-digital-radiography
#9
K Lucas, I Nolte, V Galindo-Zamora, M Lerch, C Stukenborg-Colsman, B A Behrens, A Bouguecha, S Betancur, A Almohallami, P Wefstaedt
BACKGROUND: Aseptic loosening due to bone remodelling processes after total hip replacement is one common cause for revision surgery. In human medicine, dual-energy X-ray absorptiometry (DEXA) is the gold standard for quantitative evaluation of bone mineral density, whereas in veterinary medicine conventional radiography is used for follow-up studies. Recently, a method has been described using digital X-ray images for quantitative assessment of grey scale values of bone contrast. Therefore, the aim of the present study was to evaluate the correlation of bone mineral density (BMD) measured by DEXA with grey scale values (GV) measured in digital X-ray images (RX50, RX66) ex vivo...
May 11, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28485786/rutin-prevents-the-ovariectomy-induced-osteoporosis-in-rats
#10
Q-L Wang, X-C Huo, J-H Wang, D-P Wang, Q-L Zhu, B Liu, L-L Xu
OBJECTIVE: Our study aimed to explore the anti-osteoporotic effect of rutin (quercetin-3-O-rutinose) on ovariectomized female rats. MATERIALS AND METHODS: An ovariectomized (OVX) rat model of osteoporosis was employed to evaluate the anti-osteoporotic potency of rutin. One week after surgery, the rats were administered intragastrically with rutin or saline once daily respectively for 3 months. Bone mineral density (BMD) was measured by dual-energy x-ray absorptiometry (DEXA)...
April 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28482270/metabolic-differences-between-short-children-with-gh-peak-levels-in-the-lower-normal-range-and-healthy-children-of-normal-height
#11
Anders Tidblad, Jan Gustafsson, Claude Marcus, Martin Ritzén, Klas Ekström
OBJECTIVE: Severe growth hormone deficiency (GHD) leads to several metabolic effects in the body ranging from abnormal body composition to biochemical disturbances. However, less is known regarding these parameters in short children with GH peak levels in the lower normal range during provocation tests. Our aim was to study the metabolic profile of this group and compare it with that of healthy children of normal height. DESIGN: Thirty-five pre-pubertal short children (<-2...
April 25, 2017: Growth Hormone & IGF Research
https://www.readbyqxmd.com/read/28474088/two-doses-of-low-dose-perioperative-dexamethasone-improve-the-clinical-outcome-after-total-knee-arthroplasty-a-randomized-controlled-study
#12
Bin Xu, Jun Ma, Qiang Huang, Ze-Yu Huang, Shao-Yun Zhang, Fu-Xing Pei
To study the clinical effect and safety of two doses of low-dose perioperative dexamethasone on pain and recovery after total knee arthroplasty. Methods A total of 108 patients were included in this randomized, double-blinded, placebo-controlled study. They received two doses of 10 mg IV dexamethasone (group Dexa) or IV isotonic saline (group Placebo). The CRP, IL-6 and pain levels, postoperative nausea and vomiting (PONV) incidence, nausea severity, postoperative fatigue, range of motion, length of stay, analgesic rescue and antiemetic rescue consumption, and complications were compared...
May 4, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28455680/directly-measured-free-25-hydroxy-vitamin-d-levels-show-no-evidence-of-vitamin-d-deficiency-in-young-swedish-women-with-anorexia-nervosa
#13
Martin Carlsson, Lars Brudin, Pär Wanby
PURPOSE: Anorexia nervosa (AN) is an eating disorder characterized by low fat mass complicated by osteoporosis. The role of circulating vitamin D in the development of bone loss in AN is unclear. Fat mass is known to be inversely associated with vitamin D levels measured as serum levels of total, protein-bound 25-hydroxyvitamin D, but the importance of directly measured, free levels of 25(OH)D has not been determined in AN. The aim of this study was to investigate vitamin D status, as assessed by serum concentrations of total and free serum 25(OH)D in patients with AN and healthy controls...
April 28, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28428669/risk-factors-for-osteoporosis-in-postmenopausal-women
#14
Radojka Bijelic, Snjezana Milicevic, Jagoda Balaban
INTRODUCTION: Scientific studies show that many factors related to lifestyles affect the reduction of bone mineral density and osteoporosis in postmenopausal women. GOAL: The goal of this study was to determine whether smoking, drinking coffee and alcohol in menopausal women contribute to the reduction of bone mass and osteoporosis, as well as the impact of physical activity on bone mass. MATERIAL AND METHODS: The study was carried out as case study and matched controls...
February 2017: Medical Archives
https://www.readbyqxmd.com/read/28416437/the-computed-tomography-based-fractal-analysis-of-trabecular-bone-structure-may-help-in-detecting-decreased-quality-of-bone-before-urgent-spinal-procedures
#15
Marcin Czyz, Arion Kapinas, James Holton, Renata Pyzik, Bronek M Boszczyk, Nasir A Quraishi
BACKGROUND CONTEXT: To date, no reliable method is available to determine the parameters of bone density based on the routine spinal computed tomography (CT) in the emergency setup. We propose the use of fractal analysis to detect patients with poor quality of bone before urgent or semi-urgent spinal procedures. PURPOSE: This study aimed to validate the hypothesis that the CT-based fractal analysis of the trabecular bone structure may help in detecting patients with poor quality of bone before urgent spinal procedures...
April 14, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28410836/low-preoperative-bmd-is-related-to-high-migration-of-tibia-components-in-uncemented-tka-92-patients-in-a-combined-dexa-and-rsa-study-with-2-year-follow-up
#16
Mikkel R Andersen, Nikkolaj S Winther, Thomas Lind, Henrik M Schrøder, Gunnar Flivik, Michael M Petersen
BACKGROUND: The fixation of uncemented tibia components in total knee arthroplasty may rely on the bone quality of the tibia; however, no previous studies have shown convincing objective proof of this. Component migration is relevant as it has been shown to predict aseptic loosening. METHODS: We performed 2-year follow-up of 92 patients who underwent total knee arthroplasty surgery with an uncemented tibia component. Bone mineral density (BMD; g/cm(2)) of the tibia host bone was measured preoperatively using dual energy X-ray absorptiometry...
February 28, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28401118/frequency-of-and-variation-in-low-value-care-in-primary-care-a-retrospective-cohort-study
#17
Ciara Pendrith, Meghan Bhatia, Noah M Ivers, Graham Mecredy, Karen Tu, Gillian A Hawker, Susan B Jaglal, Lynn Wilson, Kimberly Wintemute, Richard H Glazier, Wendy Levinson, R Sacha Bhatia
BACKGROUND: Low-value care, defined as care with a lack of benefit, can lead to higher health care costs, inconvenience to patients and, in some cases, harm to patients. The objectives of this study are to conduct exploratory analyses to understand how frequently selected low-value tests are ordered, to assess the degree of variation in ordering that exists across regions and practices, and to identify services that may warrant further investigation and targeted interventions. METHODS: We conducted a population-based retrospective cohort study using administrative health care databases from Ontario to identify rates of use of the following low-value services between fiscal years 2008/09 and 2012/13: computed tomography (CT) or magnetic resonance imaging (MRI) after a diagnosis of low back pain, Papanicolaou testing in women less than 21 years of age or older than 69 years of age and repeated dual-energy X-ray absorptiometry (DEXA) scanning within 2 years of an index scan...
January 2017: CMAJ Open
https://www.readbyqxmd.com/read/28390555/a-snapshot-of-patients-awareness-of-radiation-dose-and-risks-associated-with-medical-imaging-examinations-at-an-australian-radiology-clinic
#18
N Singh, A Mohacsy, D A Connell, M E Schneider
BACKGROUND: Cumulative radiation exposure is linked to increasing the lifetime attributable risk of cancer. To avoid unnecessary radiation exposure and facilitate shared decision making, patients should be aware of these issues. This paper examines patients' awareness of radiation dose and risks associated with medical imaging examinations. METHODS: Consecutive patients attending a private radiology clinic over a nine week period in 2014 in Metropolitan Melbourne were surveyed while waiting to undergo an imaging examination...
May 2017: Radiography
https://www.readbyqxmd.com/read/28387962/comparative-investigation-of-bone-mineral-density-using-ct-and-dexa-in-a-canine-femoral-model
#19
Karin Lucas, Bernd-Arno Behrens, Ingo Nolte, Vladimir Galindo-Zamora, Stefanie Betancur, Amer Almohallami, Anas Bouguecha, Ayman Mostafa, Matthias Lerch, Christina Stukenborg-Colsman, Patrick Wefstaedt
Bone density measurements using computed tomography (CT) instead of dual-energy X-ray absorptiometry (DEXA) are currently of great interest in human and veterinary medical research as it would be beneficial to use CT scans obtained for other indications also for determining bone density. For Hounsfield units (HU) measured with CT in specific regions of interests (ROIs) in one or several slice/s a corrrelation with bone mineral density (BMD) measured by DEXA in humans and dogs of between 0.44 and 0.77 is reported in the literature...
April 7, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28382607/frailty-and-primary-sarcopenia-a-review
#20
Eli Carmeli
Increasing longevity, coupled with rising frailty and sarcopenia of aging, significantly affects function and quality of life of older adults. This review discusses the definition, assessment, and management of frailty and sarcopenia, and examines the relationship between them. Medline, Scopus and Psychoinfo databases were searched using the keywords frailty, sarcopenia, aging, and functional disability. The findings are that frailty and sarcopenia are often assessed clinically with such methods such as DeXA, CT scan, MRI, bioelectrical impedance, or anthropometry...
April 6, 2017: Advances in Experimental Medicine and Biology
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