keyword
MENU ▼
Read by QxMD icon Read
search

Dexa

keyword
https://www.readbyqxmd.com/read/28816228/association-of-adiposity-telomere-length-and-mortality-data-from-the-nhanes-1999-2002
#1
J A Batsis, T A Mackenzie, E Vasquez, C M Germain, R T Emeny, P Rippberger, F Lopez-Jimenez, S J Bartels
BACKGROUND/OBJECTIVES: Telomere shortening is associated with age and risk of medical co-morbidity. We assessed the relationship between measures of adiposity, leukocyte telomere length, and mortality and whether it is modified by age. SUBJECTS/METHODS: Subjects with dual energy x-ray absorptiometry (DEXA) measures were identified using the National Health and Nutrition Examination Survey 1999-2002. Obesity was categorized using two body fat definitions (BF1%: men ⩾25%; females ⩾35%; BF2% ⩾28% and ⩾38%, respectively), body mass index (BMI), and waist circumference (WC) (men ⩾102 cm; females ⩾88 cm)...
August 16, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28815005/phase-i-study-evaluating-the-safety-tolerability-and-pharmacokinetics-of-a-novel-oral-dissolvable-film-containing-dexamethasone-versus-fortecortin-dexamethasone-tablets
#2
Zuzana Diamant, Gabriella Samuelsson Palmgren, Bengt Westrin, Leif Bjermer
Introduction: Systemic corticosteroids are anti-inflammatory agents with dexamethasone among the most potent in the class. Within (respiratory) allergy, systemic corticosteroids are usually applied in medical emergencies. In these situations, patients may experience physical or logistic problems taking tablets. To fulfil a practical unmet need for outpatients, Dexa ODF, an oral dissolvable film containing dexamethasone, was developed. Objectives: We compared the safety, tolerability and pharmacokinetics (PK) of Dexa ODF with Fortecortin tablets in healthy subjects...
2017: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28812320/the-relationship-between-periodontal-disease-tooth-loss-and-decreased-skeletal-bone-mineral-density-in-ageing-women
#3
Ivana Savić Pavičin, Jelena Dumančić, Tomislav Jukić, Tomislav Badel
AIM: Osteoporosis and periodontitis are both chronic diseases characterised by bone loss. Potential association is of great clinical importance because of multifactorial aetiology and common risk factors. The aim of this study was to determine relationship between bone mineral density (BMD), tooth loss and periodontal status taking into account age, number of years since onset of menopause and educational level. With increasing age, number of years since onset of menopause and lower educational level, decreased BMD, deteriorating periodontal status and greater tooth loss are expected...
August 15, 2017: Gerodontology
https://www.readbyqxmd.com/read/28810989/comparison-of-circumference-body-composition-measurements-and-eight-point-bioelectrical-impedance-analysis-to-dual-energy-x-ray-absorptiometry-to-measure-body-fat-percentage
#4
Travis M Combest, Robin S Howard, Anne M Andrews
BACKGROUND: To compare the circumference measurement (CM) body composition method and 8-point segmental bioelectrical impedance analysis (DSM-BIA) to dual energy X-ray absorptiometry (DEXA) in military members. OBJECTIVE: The objective was to compare three body composition methods. Our hypothesis was the CM is as accurate as DSM-BIA and DEXA in assessing body fat percentage (%BF). DESIGN: Cross sectional, observational study. PARTICIPANTS/SETTING: Healthy active duty military males and nonpregnant females...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28780621/an-international-consensus-on-the-appropriate-evaluation-and-treatment-for-adults-with-spinal-deformity
#5
Sigurd H Berven, Steven J Kamper, Niccole M Germscheid, Benny Dahl, Christopher I Shaffrey, Lawrence G Lenke, Stephen J Lewis, Kenneth M Cheung, Ahmet Alanay, Manabu Ito, David W Polly, Yong Qiu, Marinus de Kleuver
PURPOSE: Evaluation and surgical management for adult spinal deformity (ASD) patients varies between health care providers. The purpose of this study is to identify appropriateness of specific approaches and management strategies for the treatment of ASD. METHODS: From January to July 2015, the AOSpine Knowledge Deformity Forum performed a modified Delphi survey where 53 experienced deformity surgeons from 24 countries, rated the appropriateness of management strategies for multiple ASD clinical scenarios...
August 5, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28765165/the-relationship-between-body-composition-and-bone-quality-measured-with-hr-pqct-in-peritoneal-dialysis-patients
#6
Coralie Fournie, Solenne Pelletier, Justine Bacchetta, Stéphanie Boutroy, Cyrille Confavreux, Jocelyne Drai, Walid Arkouche, Denis Fouque, Roland Chapurlat, Fitsum Guebre-Egziabher
BACKGROUND: Bone is known to be impaired in chronic kidney disease and dialysis patients. Recent studies have shown that body composition (fat mass and lean mass) may impact bone health. Some of these effects may be related to mediators that are secreted by adipose tissue. METHODS: The aim of this study was to evaluate the association between body composition (dual x-ray absorptiometry [DEXA]) and adipokines (leptin, adiponectin), with bone density and microarchitecture assessed with high-resolution peripheral quantitative computed tomography (HR-pQCT) in chronic peritoneal dialysis (PD) patients in a single-center prospective study...
August 1, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28763099/autologous-tolerogenic-dendritic-cells-derived-from-monocytes-of-systemic-lupus-erythematosus-patients-and-healthy-donors-show-a-stable-and-immunosuppressive-phenotype
#7
Javiera Obreque, Fabián Vega, Andy Torres, Loreto Cuitino, Juan P Mackern-Oberti, Paola Viviani, Alexis Kalergis, Carolina Llanos
Systemic Lupus Erythematosus (SLE) is an autoimmune disease with unrestrained T-cell and B cell activity towards self-antigens. Evidence shows that apoptotic cells (ApoCells) trigger an autoreactive response against nuclear antigens in susceptible individuals. In this study, we focus on generating and characterizing tolerogenic dendritic cells (tolDCs) to restore tolerance to ApoCells. Monocyte-derived dendritic cells (DCs) from healthy controls (HC) and SLE patients were treated with dexamethasone (DEXA) and rosiglitazone (RGZ) to induce tolDCs...
August 1, 2017: Immunology
https://www.readbyqxmd.com/read/28744812/in-vivo-effects-of-dexamethasone-on-blood-gene-expression-in-ataxia-telangiectasia
#8
Michele Menotta, Sara Biagiotti, Sara Orazi, Luigia Rossi, Luciana Chessa, Vincenzo Leuzzi, Daniela D'Agnano, Alessandro Plebani, Annarosa Soresina, Mauro Magnani
Ataxia telangiectasia (AT) is a rare incurable genetic disease caused by biallelic mutations in the Ataxia telangiectasia-mutated gene. Intra-erythrocyte infusion of dexamethasone improves clinical outcomes in AT patients; however, the molecular mechanisms that lead to this improvement remain unknown. Hence, to gain a better understanding of these mechanisms, we assessed the effects of glucocorticoid administration on gene expression in the blood of AT patients. Whole blood was obtained from nine children enrolled in a phase two clinical trial, who were being treated with dexamethasone (AT Dexa), from six untreated AT patients (AT) and from six healthy volunteers (WT)...
July 25, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28744736/management-of-bone-health-in-postmenopausal-women-on-aromatase-inhibitors-ais-a-single-health-care-system-experience
#9
Douglas Tremblay, Vaibhav Patel, Kenneth M Fifer, Jessica Caro, Olivia Kolodka, John Mandelli, Charles L Shapiro
INTRODUCTION: Aromatase inhibitors (AIs) are the preferred therapy for postmenopausal women with early-stage estrogen receptor-positive breast cancers. However, their use causes bone loss and increased risks of osteoporosis and fractures. METHODS: This is a retrospective review of all postmenopausal women with breast cancer diagnosed and treated with AI between 2010 and 2015. Of the 564 women identified, 319 were eligible. RESULTS: The median age at AI initiation was 65 years (range 51-85 years), and the median duration of AI therapy was 28 months (1-72 months)...
July 26, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28742506/bioimpedance-analysis-vs-dexa-as-a-screening-tool-for-osteosarcopenia-in-lean-overweight-and-obese-caucasian-postmenopausal-females
#10
Melpomeni Peppa, Charikleia Stefanaki, Athanasios Papaefstathiou, Dario Boschiero, George Dimitriadis, George P Chrousos
BACKGROUND-OBJECTIVES: We aimed at evaluating the efficiency of a newly developed, advanced Bioimpedance Analysis (BIA-ACC®) device as a screening tool for determining the degree of obesity and osteosarcopenia in postmenopausal women with normal or decreased bone density determined by Dual-Energy X-Ray absorptiometry (DEXA) in a representative sample of Greek postmenopausal women. METHODS: This is a single-gate cross-sectional study of body composition measured by BIA-ACC® and DEXA...
April 2017: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28742266/p-coumaric-acid-a-dietary-polyphenol-ameliorates-inflammation-and-curtails-cartilage-and-bone-erosion-in-the-rheumatoid-arthritis-rat-model
#11
Manoj Kumar Neog, Samuel Joshua Pragasam, Moorthy Krishnan, Mahaboobkhan Rasool
This study was designed to explore the underlying mechanism of p-coumaric acid (CA), a dietary polyphenol in adjuvant-induced arthritis (AIA) rat model with reference to synovitis and osteoclastogenesis. Celecoxib (COX-2 selective inhibitor) (5 mg/kg b.wt) was used as a reference drug. CA remarkably suppressed the paw edema, body weight loss and inflammatory cytokine and chemokine levels (TNF-α, IL-1β, IL-6, and MCP-1) in serum and ankle joint of arthritic rats. Consistently, CA reduced the expression of osteoclastogenic factors (RANKL and TRAP), pro-inflammatory cytokines (TNF-α, IL-1β, IL-6, and IL-17), and inflammatory enzymes (iNOS and COX-2) in arthritic rats...
July 25, 2017: BioFactors
https://www.readbyqxmd.com/read/28736691/prevalence-and-risk-factors-of-osteoporosis-among-jordanian-postmenopausal-women-attending-the-national-center-for-diabetes-endocrinology-and-genetics-in-jordan
#12
Dana Hyassat, Taghreed Alyan, Hashem Jaddou, Kamel M Ajlouni
To assess the prevalence of osteoporosis and osteopenia among Jordanian postmenopausal women attending the National Center for Diabetes, Endocrinology, and Genetics (NCDEG), and to determine the potential associated risk factors. A cross-sectional study was conducted at (NCDEG) in Amman, Jordan. A total of 1079 Jordanian postmenopausal women aged between 45 and 84 years were included in this study that was conducted during the period between April 2013 and December 2014. All patients underwent bone mineral density measurement through dual-energy X-ray absorptiometry (DEXA) scan...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/28726334/insulin-sensitivity-across-the-lifespan-from-obese-adolescents-to-obese-adults-with-impaired-glucose-tolerance-who-is-worse-off
#13
Silva Arslanian, Joon Young Kim, Alexis Nasr, Fida Bacha, Hala Tfayli, SoJung Lee, Frederico G S Toledo
OBJECTIVE: Youth type 2 diabetes mellitus (T2DM) occurs decades earlier than adult T2DM and is characterized by high therapeutic failure rates and decreased response to insulin sensitizers suggesting a more severe disease process than in adults. To explain these observations, we hypothesized that insulin resistance is worse in obese youth than adults with impaired glucose tolerance (IGT), a state of high-risk for T2DM. As proof-of-concept, we compared insulin sensitivity between BMI-, sex-, and race-matched obese youth vs adults with IGT...
July 20, 2017: Pediatric Diabetes
https://www.readbyqxmd.com/read/28717072/the-relationship-of-bone-mineral-density-in-men-with-chronic-obstructive-pulmonary-disease-classified-according-to-the-global-initiative-for-chronic-obstructive-lung-disease-gold-combined-chronic-obstructive-pulmonary-disease-copd-assessment-system
#14
Yoriko Sakurai-Iesato, Naoko Kawata, Yuji Tada, Ken Iesato, Yukiko Matsuura, Misuzu Yahaba, Toshio Suzuki, Jun Ikari, Noriyuki Yanagawa, Yasunori Kasahara, James West, Koichiro Tatsumi
Objective Osteoporosis, which is now recognized as a major comorbidity of chronic obstructive pulmonary disease (COPD), must be diagnosed by appropriate methods. The aims of this study were to clarify the relationships between bone mineral density (BMD) and COPD-related clinical variables and to explore the association of BMD with the updated Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification in men. Methods We enrolled 50 Japanese men with clinically stable COPD who underwent dual-energy X-ray absorptiometry (DEXA), pulmonary function testing, and computerized tomography (CT) and who had completed a questionnaire (COPD assessment test [CAT])...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28708200/periacetabular-bone-densitometry-after-total-hip-arthroplasty-with-highly-porous-titanium-cups-a-2-year-follow-up-prospective-study
#15
Leo Massari, Alessandro Bistolfi, Pier Paolo Grillo, Alda Borré, Gaetano Gigliofiorito, Carlotta Pari, Andrea Francescotto, Piermario Tosco, Davide Deledda, Laura Ravera, Araldo Causero
INTRODUCTION: Trabecular Titanium is an advanced cellular solid structure, composed of regular multiplanar hexagonal interconnected cells that mimic the morphology of the trabecular bone. This biomaterial demonstrated improved mechanical properties and enhanced osteoinduction and osteoconduction in several in vitro and in vivo studies. The aim of this study was to assess Trabecular Titanium osseointegration by measuring periacetabular changes in bone mineral density (BMD) with dual-emission X-ray absorptiometry (DEXA)...
July 1, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28706360/osteoporosis-prevention-and-management
#16
Muralidhar V Pai
Osteoporosis, defined by BMD at the hip or lumbar spine that is less than or equal to 2.5 standard deviations below the mean BMD of a young-adult reference population, is the most common bone disease in humans affecting both sexes and all races. It's a silent killer affecting the quality of life due to fractures and postural changes. In osteoporosis there is an imbalance between bone formation and bone resorption in favor of latter. Preventive measures and treatments are available to combat this evil. Counseling is the integral part of prevention as well as treatment of osteoporosis...
August 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28696825/androgen-status-in-non-diabetic-elderly-men-with-heart-failure
#17
Goran Loncar, Biljana Bozic, Aleksandar N Neskovic, Natasa Cvetinovic, Mitja Lainscak, Nenad Prodanovic, Hans-Dirk Dungen, Stephan von Haehling, Zoran Radojicic, Tobias Trippel, Biljana Putnikovic, Natasa Markovic-Nikolic, Vera Popovic
PURPOSE: We aimed at evaluating androgen status (serum testosterone [TT] and estimated free testosterone [eFT]) and its determinants in non-diabetic elderly men with heart failure (HF). Additionally, we investigated its associations with body composition and long-term survival. METHODS: Seventy three non-diabetic men with HF and 20 healthy men aged over 55 years were studied. Echocardiography, 6-min walk test, grip strength, body composition measurement by DEXA method were performed...
July 11, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28693592/bone-metabolism-and-inflammatory-characteristics-in-14-cases-of-chronic-nonbacterial-osteomyelitis
#18
Yurika Ata, Yutaka Inaba, Hyonmin Choe, Naomi Kobayashi, Jiro Machida, Naoyuki Nakamura, Tomoyuki Saito
BACKGROUND: Chronic nonbacterial osteomyelitis (CNO) is a multifocal autoinflammatory disease that often impairs daily life in children. This study aimed to investigate the bone metabolic and inflammatory characteristics of patients with CNO, and to assess the differences between responders and nonresponders to conservative treatment. METHODS: We investigated the clinical symptoms; laboratory data including inflammatory and bone metabolic biomarkers; and imaging findings from plain radiography, magnetic resonance imaging (MRI), fluorodeoxyglucose-positron emission tomography (FDG-PET), and dual-energy x-ray absorption (DEXA) in 14 patients with CNO...
July 11, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28687542/skeletal-muscle-microvascular-linked-improvements-in-glycemic-control-from-resistance-training-in-individuals-with-type-2-diabetes
#19
Ryan D Russell, Donghua Hu, Timothy Greenaway, Sarah J Blackwood, Renee M Dwyer, James E Sharman, Graeme Jones, Kathryn A Squibb, Aascha A Brown, Petr Otahal, Meg Boman, Hayder Al-Aubaidy, Dino Premilovac, Christian K Roberts, Samuel Hitchins, Stephen M Richards, Stephen Rattigan, Michelle A Keske
OBJECTIVE: Insulin increases glucose disposal in part by enhancing microvascular blood flow (MBF) and substrate delivery to myocytes. Insulin's microvascular action is impaired with insulin resistance and type 2 diabetes. Resistance training (RT) improves glycemic control and insulin sensitivity, but whether this improvement is linked to augmented skeletal muscle microvascular responses in type 2 diabetes is unknown. RESEARCH DESIGN AND METHODS: Seventeen (11 male and 6 female; 52 ± 2 years old) sedentary patients with type 2 diabetes underwent 6 weeks of whole-body RT...
July 7, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28685283/short-term-effects-of-extracorporeal-shock-wave-therapy-on-bone-mineral-density-in-postmenopausal-osteoporotic-patients
#20
L Shi, F Gao, W Sun, B Wang, W Guo, L Cheng, Z Li, W Wang
It has been proved that extracorporeal shock wave therapy (ESWT) could promote new bone formation. Therefore, we designed an experiment to test the efficiency of ESWT on BMD in postmenopausal osteoporotic patients. The results showed that ESWT could effectively improve the local bone mass of the treated bone area within a short duration. INTRODUCTION: This study evaluated the short-term effectiveness of extracorporeal shock wave therapy (ESWT) on bone mineral density (BMD). METHODS: A total of 64 postmenopausal osteoporotic patients were recruited and randomized into 3 groups in 2015...
July 6, 2017: Osteoporosis International
keyword
keyword
8971
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"