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https://www.readbyqxmd.com/read/29776399/simulation-based-power-calculations-for-planning-a-two-stage-individual-participant-data-meta-analysis
#1
Joie Ensor, Danielle L Burke, Kym I E Snell, Karla Hemming, Richard D Riley
BACKGROUND: Researchers and funders should consider the statistical power of planned Individual Participant Data (IPD) meta-analysis projects, as they are often time-consuming and costly. We propose simulation-based power calculations utilising a two-stage framework, and illustrate the approach for a planned IPD meta-analysis of randomised trials with continuous outcomes where the aim is to identify treatment-covariate interactions. METHODS: The simulation approach has four steps: (i) specify an underlying (data generating) statistical model for trials in the IPD meta-analysis; (ii) use readily available information (e...
May 18, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29775388/epidemiology-of-elbow-ulnar-collateral-ligament-injuries-among-baseball-players-national-collegiate-athletic-association-injury-surveillance-program-2009-2010-through-2013-2014
#2
Steven F DeFroda, Avi D Goodman, Joseph A Gil, Brett D Owens
BACKGROUND: Injuries to the ulnar collateral ligament (UCL) of the elbow are of major concern in baseball; however, the epidemiology of these injuries among National Collegiate Athletic Association (NCAA) athletes is poorly described. PURPOSE: To determine the incidence of UCL injuries in NCAA baseball and investigate the risk factors involved. STUDY DESIGN: Descriptive epidemiology study. METHODS: All UCL injuries for academic years 2009-2010 through 2013-2014 were extracted from the NCAA Injury Surveillance Program database...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29771138/rate-of-upper-extremity-injury-in-high-school-baseball-pitchers-who-played-catcher-as-a-secondary-position
#3
Elizabeth E Hibberd, Sakiko Oyama, Joseph B Myers
CONTEXT:   Many high school pitchers play another position after they have finished pitching for the day or on their rest days from pitching. Because of the cumulative demands on the arm, pitchers who also play catcher may have a greater risk of developing a throwing-related shoulder or elbow injury. OBJECTIVE:   To compare the rate of throwing-related upper extremity injuries between high school baseball pitchers who also played catcher as a secondary position and those who did not play catcher...
May 17, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29770861/the-fate-of-fogli-s-lore-s-fascial-platysma-fixation-optimalising-the-results-of-fogli-s-neck-lift-procedure
#4
Darryl J Hodgkinson
The author has modified previously described techniques of the superior suspension of the platysma muscle to Lore's fascia by developing an auriculoplastysmal fascial flap, which detaches the posterior platysma from its retaining ligaments to the sternomastoid muscle. Anterior to this flap, the platysma muscle is undermined and suture captured with three throws of a permanent 2.0 Tevdek suture. This suture and its three throws are fixed anterior to the tragus, which includes Lore's fascia and on tightening elevates the whole of the anterior neck as well as defines the cervicomental angle...
May 16, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29769820/multivariate-relationships-among-morphology-fitness-and-motor-coordination-in-prepubertal-girls
#5
Leonardo G O Luz, Manuel J Coelho-E-Silva, João P Duarte, João Valente-Dos-Santos, Aristides Machado-Rodrigues, André Seabra, Bruno C M Carmo, Roel Vaeyens, Renaat M Philippaerts, Sean P Cumming, Robert M Malina
Motor coordination and physical fitness are multidimensional concepts which cannot be reduced to a single variable. This study evaluated multivariate relationships among morphology, physical fitness and motor coordination in 74 pre-pubertal girls 8.0-8.9 years of age. Data included body dimensions, eight fitness items and four motor coordination tasks (KTK battery). Maturity status was estimated as percentage of predicted mature stature attained at the time of observation. Canonical correlation analysis was used to examine the relationships between multivariate domains...
June 2018: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29769009/mesenchymal-stem-cell-research-in-veterinary-medicine
#6
Mudasir Bashir Gugjoo, Amarpal, Vikash Chandra, Mohd Yaqoob Wani, Kuldeep Dhama, Gutulla Taru Sharma
BACKGROUND: The stem cells due to their unique characteristic features like self-renewal, multiplication, immuno-modulation and differentiation, are seen and hoped to bring new horizons in the field of biology, in general and medicine, in particular. OBJECTIVE: Among various stem cell types, currently mesenchymal stem cells (MSCs) are extensively studied in regenerative medicine owing to their readily available sources, easy harvesting and ability to differentiate both into mesodermal as well as non-mesodermal tissues with little associated ethical issues...
May 16, 2018: Current Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29758570/acute-hip-abduction-fatigue-on-lumbopelvic-hip-complex-stability-in-softball-players
#7
Jessica Washington, Gabrielle Gilmer, Gretchen Oliver
During an overhead throw, the gluteal muscle group stabilizes the lumbopelvic-hip complex (LPHC), leading to efficient energy transfer from the lower to upper extremity. It has been shown that LPHC instability can lead to throwing pathomechanics. The single leg squat has become a common assessment for LPHC stability, and could be used to determine the effects of fatigue on throwing athletes. The purpose of this study was to determine the effects of an acute abduction fatigue protocol on the LPHC of collegiate softball players via the single leg squat assessment of the leg ipsilateral to the throwing arm...
May 14, 2018: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29755389/evidence-for-sequential-performance-effects-in-professional-darts
#8
John F Stins, Gur Yaari, Kevin Wijmer, Joost F Burger, Peter J Beek
Objectives: The study of sequential effects in aiming tasks might shed light on the organization of repetitive motor performances over time. To date, investigations of such effects in sports have been limited and yielded mixed results. Given the relatively short time intervals between successive attempts, and the absence of defensive interventions, dart throwing provides a potentially fruitful testing ground for examining the presence of sequential performance effects in the motor domain. Methods and Results: A total of 80 competitive darts matches of 10 of the world's best players were scored from publicly available video footage in terms of sequences of hits and misses of triple 20...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29754522/clinical-measurement-of-the-dart-throwing-motion-of-the-wrist-variability-accuracy-and-correction
#9
Vasiliki Vardakastani, Hannah Bell, Sarah Mee, Gavin Brigstocke, Angela E Kedgley
Despite being functionally important, the dart throwing motion is difficult to assess accurately through goniometry. The objectives of this study were to describe a method for reliably quantifying the dart throwing motion using goniometric measurements within a healthy population. Wrist kinematics of 24 healthy participants were assessed using goniometry and optical motion tracking. Three wrist angles were measured at the starting and ending points of the motion: flexion-extension, radial-ulnar deviation and dart throwing motion angle...
January 1, 2018: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29746146/predictors-of-elbow-torque-among-youth-and-adolescent-baseball-pitchers
#10
Kelechi R Okoroha, Vincent A Lizzio, Fabien Meta, Christopher S Ahmad, Vasilios Moutzouros, Eric C Makhni
BACKGROUND: There has been an increasing incidence of overuse elbow injuries among youth and adolescent pitchers. Pitch type has been implicated as a risk factor for excess torque at the medial elbow; however, this has not been definitively demonstrated. PURPOSE: To assess predictors of torque across the medial elbow in youth and adolescent pitchers with a mobile sensor. In addition, the authors aimed to determine the differences in elbow torque produced according to pitch type (fastball, curveball, changeup) and pitcher demographics...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29745853/a-new-method-to-measure-the-semantic-similarity-from-query-phenotypic-abnormalities-to-diseases-based-on-the-human-phenotype-ontology
#11
Xiaofeng Gong, Jianping Jiang, Zhongqu Duan, Hui Lu
BACKGROUND: Although rapid developed sequencing technologies make it possible for genotype data to be used in clinical diagnosis, it is still challenging for clinicians to understand the results of sequencing and make correct judgement based on them. Before this, diagnosis based on clinical features held a leading position. With the establishment of the Human Phenotype Ontology (HPO) and the enrichment of phenotype-disease annotations, there throws much more attention to the improvement of phenotype-based diagnosis...
May 8, 2018: BMC Bioinformatics
https://www.readbyqxmd.com/read/29742572/development-of-human-face-literature-database-using-text-mining-approach-phase-i
#12
Paramjit Kaur, Kewal Krishan, Suresh K Sharma
The face is an important part of the human body by which an individual communicates in the society. Its importance can be highlighted by the fact that a person deprived of face cannot sustain in the living world. The amount of experiments being performed and the number of research papers being published under the domain of human face have surged in the past few decades. Several scientific disciplines, which are conducting research on human face include: Medical Science, Anthropology, Information Technology (Biometrics, Robotics, and Artificial Intelligence, etc...
May 8, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29740559/comparison-of-special-judo-fitness-test-and-dynamic-and-isometric-judo-chin-up-tests-performance-and-classificatory-tables-development-for-cadet-and-junior-athletes
#13
Marcus Fábio Agostinho, José Alfredo Olivio Junior, Nemanja Stankovic, Raquel Escobar-Molina, Emerson Franchini
The aims of this work were to compare the performances of male and female cadet and junior judo athletes and to develop classificatory tables to these judo-specific tests for international-level from these ages. Data collected during training camps of male and female cadet and junior judo teams from three nations (Brazil, Serbia, and Spain) were analyzed, totalizing 252 individual results of special judo fitness test (SJFT), and 222 and 208 of dynamic and isometric judogi chin-up tests, respectively. Juniors performed better than cadets in the SJFT, with higher number of throws in A, B, C, and total ( P <0...
April 2018: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29738281/epidemiology-of-figure-skating-injuries-a-review-of-the-literature
#14
Julie S Han, Ellen T Geminiani, Lyle J Micheli
CONTEXT: As the popularity and technical demands of figure skating increase, so will the number of athletes presenting with sport-related problems. EVIDENCE ACQUISITION: Searches were performed across PubMed from 1980 to 2017. The keywords searched were skating, skaters, incidence, and injuries. The search was limited to English-language articles and human participants. Relevant articles were cross-referenced. STUDY DESIGN: Clinical review...
May 1, 2018: Sports Health
https://www.readbyqxmd.com/read/29723668/why-do-proteases-mess-up-with-antigen-presentation-by-re-shuffling-antigen-sequences
#15
REVIEW
Juliane Liepe, Huib Ovaa, Michele Mishto
The sequence of a large number of MHC-presented epitopes is not present as such in the original antigen because it has been re-shuffled by the proteasome or other proteases. Why do proteases throw a spanner in the works of our model of antigen tagging and immune recognition? We describe in this review what we know about the immunological relevance of post-translationally spliced epitopes and why proteases seem to have a second (dark) personality, which is keen to create new peptide bonds.
April 30, 2018: Current Opinion in Immunology
https://www.readbyqxmd.com/read/29719738/motor-experience-with-a-sport-specific-implement-affects-motor-imagery
#16
Lanlan Zhang, Yanling Pi, Hua Zhu, Cheng Shen, Jian Zhang, Yin Wu
The present study tested whether sport-specific implements facilitate motor imagery, whereas nonspecific implements disrupt motor imagery. We asked a group of basketball players (experts) and a group of healthy controls (novices) to physically perform (motor execution) and mentally simulate (motor imagery) basketball throws. Subjects produced motor imagery when they were holding a basketball, a volleyball, or nothing. Motor imagery performance was measured by temporal congruence, which is the correspondence between imagery and execution times estimated as (imagery time minus execution time) divided by (imagery time plus execution time), as well as the vividness of motor imagery...
2018: PeerJ
https://www.readbyqxmd.com/read/29718915/are-canadian-born-major-league-baseball-players-more-likely-to-bat-left-handed-a-partial-test-of-the-hockey-influence-on-batting-hypothesis
#17
John Cairney, Daniele Chirico, Yao-Chuen Li, Emily Bremer, Jeffrey D Graham
It has been suggested that Canadian-born Major League Baseball (MLB) players are more likely to bat left-handed, possibly owing to the fact that they learn to play ice hockey before baseball, and that there is no clear hand-preference when shooting with a hockey stick; approximately half of all ice hockey players shoot left. We constructed a database on active (i.e., October, 2016) MLB players from four countries/regions based on place of birth (Canada, United States of America [USA], Dominican Republic and South Asia [i...
2018: PloS One
https://www.readbyqxmd.com/read/29715581/equal-kinematics-and-visual-context-but-different-purposes-observer-s-moral-rules-modulate-motor-resonance
#18
Laila Craighero, Sonia Mele
Motor resonance is considered to be an index of the automatic under threshold motor replica of the observed action. Similar actions may be quite different in terms of long-term goals (e.g., grasp to eat vs grasp to throw) and, recently, it has been proposed that the distal goal subtly modulates movements execution, and that observers automatically use these differences in kinematics to discriminate between different intentions. This interpretation is in line with computational approaches proposing that in the agent the generative process causes that intention shapes the kinematics, and in the observer the recognition process causes that the kinematics cues the intention...
April 9, 2018: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29712541/refractory-ulnar-nerve-symptoms-in-an-adolescent-pitcher-with-medial-apophysitis
#19
Aaron R Hellem, Elena J Jelsing, Wendy J Hurd
A 16-year-old high school baseball pitcher with a 3-week history of acute-onset pain in his medial elbow during throwing presented to physical therapy. Following examination, physical therapy was initiated and the patient was referred for imaging, with suspicion of ulnar collateral ligament (UCL) injury. Radiographs were noncontributory. Ultrasound imaging, however, was performed by a physiatrist and was suggestive of a partial-thickness tear of the UCL and ulnar nerve enlargement. The physiatrist ordered magnetic resonance imaging, which confirmed a medial apophyseal stress reaction, a mild UCL sprain, and reactive ulnar nerve edema...
May 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29709639/dnmt1-mediated-promoter-methylation-of-gnao1-in-hepatoma-carcinoma-cells
#20
Diannan Xu, Meiling Du, Jun Zhang, Panpan Xiong, Wenshuai Li, Huilu Zhang, Wujun Xiong, Fei Liu, Jie Liu
Hepatocellular carcinoma (HCC) is one of the most lethal and prevalent cancers worldwide and has recently become the second most common cause of cancer-related deaths in men of developing countries. Guanine nucleotide-binding protein (G protein) has been reported to be associated with the early process of HCC. In our previous study, GNAO1, one of members of G protein, was found to be down-regulated in HCC. Thus, the present study aimed to throw light upon the mechanism of the abnormal expression of GNAO1 in HCC...
April 27, 2018: Gene
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