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https://www.readbyqxmd.com/read/29351518/-i-m-still-dad-the-impact-of-scleroderma-on-being-a-father
#1
Janet L Poole, Donna Haygood, Cindy Mendelson
The purpose of this study was to describe the experiences of fathers with scleroderma. Ten fathers with scleroderma were interviewed by telephone. Interviews were tape-recorded and transcribed verbatim. Two key themes emerged related to the emotional impact of the illness and the day to day realities of the illness with the unpredictability and rareness of the illness leading to ongoing feelings of isolation and fear of mortality. The negative influences of being a father with scleroderma included the inability of the fathers to participate in physical activities with their children such as outdoor sports and throwing balls...
January 2018: Occupational Therapy in Health Care
https://www.readbyqxmd.com/read/29350555/outcomes-of-latarjet-procedure-compared-with-bankart-repair-for-recurrent-traumatic-anterior-shoulder-instability
#2
Kellie C Huxel Bliven, Gail P Parr
Reference/Citation:  An VV, Sivakumar BS, Phan K, Trantalis J. A systematic review and meta-analysis of clinical and patient-reported outcomes following two procedures for recurrent traumatic anterior instability of the shoulder: Latarjet procedure vs. Bankart repair. J Shoulder Elbow Surg. 2016;25(5):853-863. CLINICAL QUESTION:   Are clinical and patient-reported outcomes different between the Latarjet and Bankart repair stabilization procedures when performed for recurrent traumatic anterior shoulder instability? DATA SOURCES:   Ovid MEDLINE, PubMed, Cochrane databases, American College of Physicians Journal Club, and Database of Abstracts of Review of Effectiveness were searched up to June 2015...
January 19, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29350110/construct-validity-of-the-resistance-training-skills-battery-in-children-aged-7-10-years
#3
Michael J Duncan, Chelsey Lawson, Josh Hurst, Jason Tallis, Victoria Jones, Emma L J Eyre
The current study sought to examine the construct validity of the Resistance Training Skills Battery for Children (RTSBc), a movement screen purported to assess resistance training skill in children. Children aged 7-10 years (n = 27, 21 males, 6 females) undertook measures of resistance training skill via the RTSBc, motor competence and muscular fitness. Using a median split for RTSBc scores, children were categorised as high or low resistance training competence. Univariate ANCOVAs, controlling for maturation, were used to examine whether measures of muscular fitness and motor competence scores differed as a function of RTSBc competence...
January 19, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29345343/mycobacterium-tuberculosis-rewiring-host-cell-signaling-to-promote-infection
#4
REVIEW
Michael D Stutz, Michelle P Clark, Marcel Doerflinger, Marc Pellegrini
The ability of Mycobacterium tuberculosis to cause disease hinges upon successfully thwarting the innate defenses of the macrophage host cell. The pathogen's trump card is its armory of virulence factors that throw normal host cell signaling into disarray. This process of subverting the macrophage begins upon entry into the cell, when M. tuberculosis actively inhibits the fusion of the bacilli-laden phagosomes with lysosomes. The pathogen then modulates an array of host signal transduction pathways, which dampens the macrophage's host-protective cytokine response, while simultaneously adapting host cell metabolism to stimulate lipid body accumulation...
December 15, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/29340300/shared-mechanisms-in-the-estimation-of-self-generated-actions-and-the-prediction-of-other-s-actions-by-humans
#5
Tsuyoshi Ikegami, Gowrishankar Ganesh
The question of how humans predict outcomes of observed motor actions by others is a fundamental problem in cognitive and social neuroscience. Previous theoretical studies have suggested that the brain uses parts of the forward model (used to estimate sensory outcomes of self-generated actions) to predict outcomes of observed actions. However, this hypothesis has remained controversial due to the lack of direct experimental evidence. To address this issue, we analyzed the behavior of darts experts in an understanding learning paradigm and utilized computational modeling to examine how outcome prediction of observed actions affected the participants' ability to estimate their own actions...
November 2017: ENeuro
https://www.readbyqxmd.com/read/29331642/protein-adaptations-in-extremophiles-an-insight-into-extremophilic-connection-of-mycobacterial-proteome
#6
REVIEW
Ashutosh Kumar, Anwar Alam, Deeksha Tripathi, Mamta Rani, Hafeeza Khatoon, Saurabh Pandey, Nasreen Z Ehtesham, Seyed E Hasnain
The biological paradox about how extremophiles persist at extreme ecological conditions throws a fascinating picture of the enormous potential of a single cell to adapt to homeostatic conditions in order to propagate. Unicellular organisms face challenges from both environmental factors and the ecological niche provided by the host tissue. Although the existence of extremophiles and their physiological properties were known for a long time, availability of whole genome sequence has catapulted the study on mechanisms of adaptation and the underlying principles that have enabled these unique organisms to withstand evolutionary and environmental pressures...
January 10, 2018: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/29330670/treatment-of-partial-thickness-rotator-cuff-tears-in-overhead-athletes
#7
REVIEW
Joseph N Liu, Grant H Garcia, Anirudh K Gowd, Brandon C Cabarcas, Michael D Charles, Anthony A Romeo, Nikhil N Verma
PURPOSE OF REVIEW: To review the etiology, classification, presentation, evaluation, treatment strategy, and outcomes in overhead athletes with partial thickness rotator cuff tears. RECENT FINDINGS: Despite advances in surgical repair techniques, return to play following surgical repair of partial rotator cuff tears remains modest at best. Overhead athletes may be particularly prone to rotator cuff pathology due to the supraphysiological strains within the tendon during the throwing motion, as well as mechanical stress with contact between the undersurface of the rotator cuff and the glenoid...
January 13, 2018: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/29330669/hip-and-groin-injuries-in-baseball-players
#8
REVIEW
Ryan A Mlynarek, Struan H Coleman
PURPOSE OF REVIEW: To discuss the clinical significance of the most common hip and groin injuries in baseball players, as well as an algorithmic approach to diagnosis and treatment of these injuries. RECENT FINDINGS: (a) Limitations in throwing velocity, pitch control, and bat swing speed may be secondary to decreased mobility and strength within the proximal kinetic chain, which must harness power from the lower extremities and core. (b) Approximately 5.5% of all baseball injuries per year involve the hip/groin and may lead to a significant amount of time spent on the disabled list...
January 12, 2018: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/29329969/inattentional-blindness-on-the-full-attention-trial-are-we-throwing-out-the-baby-with-the-bathwater
#9
REVIEW
Rebekah C White, Martin Davies, Anne M Aimola Davies
When attention is otherwise engaged, observers may experience inattentional blindness, failing to notice objects or events that are presented in plain sight. In an inattentional blindness experiment, an unexpectedstimulus ispresented alongside primary-task stimuli, and its detection is probed. We evaluate a criterion that is commonly used to exclude observers from the data analysis. On the final experimental trial, observers do not perform the primary task, but instead look for anything new. Observers who fail to report the unexpected stimulus on thisfull-attention trialare excluded...
January 9, 2018: Consciousness and Cognition
https://www.readbyqxmd.com/read/29326896/relationship-between-sitting-volleyball-performance-and-field-fitness-of-sitting-volleyball-players-in-korea
#10
Bogja Jeoung
The purpose of this study was to evaluate the relationship between sitting volleyball performance and the field fitness of sitting volleyball players. Forty-five elite sitting volleyball players participated in 10 field fitness tests. Additionally, the players' head coach and coach assessed their volleyball performance (receive and defense, block, attack, and serve). Data were analyzed with SPSS software version 21 by using correlation and regression analyses, and the significance level was set at P< 0.05...
December 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29326494/experience-of-an-academic-institute-in-importing-a-novel-preclinical-drug-into-india
#11
M Praveen Kumar, Bikash Medhi
The article throws light on the process of importing a novel preclinical drug into India based on the real-life experience from one of our studies. A novel drug "X" acting through a new mechanism of action was hypothesized by us to function as a neuroprotectant. It was decided to import this novel drug from a university located in Brazil. An official collaboration pact was exchanged between both the sides. In accordance with the Indian Drug and Cosmetics Act 1940, unauthorized import of drug into India is not permitted...
July 2017: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/29323072/orofacial-granulomatosis-a-disease-or-a-concealed-warning
#12
Priya Anil Bhagde, Jyoti D Bhavthankar, Mandakini Mandale
Granulomatosis is any condition characterized by the formation of multiple nodules or granulomas in the soft tissues. Differential diagnosis for orofacial region includes a wide spectrum of diseases, but most of these lesions present histopathologically as noncaseating granulomas, giving a nonspecific depiction and leading to a diagnostic impasse. In the absence of any diagnosable entity, the disease is labelled as "orofacial granulomatosis". A nine-year-old girl child reported with recurrent gingival enlargement and persistent macrochelia which histopathologically presented as noncaseating granulomas...
October 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29322208/the-association-of-the-medial-joint-vacuum-phenomenon-with-ulnar-collateral-ligament-injury-in-symptomatic-elbows-of-younger-athletes
#13
Ryan Tai, Tyson Bolinske, Varand Ghazikhanian, Jacob C Mandell
OBJECTIVE: To determine the prevalence of intra-articular gas (IAG) on elbow radiography and evaluate variables, including IAG, as predictors of UCL injury. MATERIALS AND METHODS: This IRB-approved retrospective study consisted of 241 consecutive elbow radiographic studies containing AP radiographs with valgus stress of both symptomatic and asymptomatic sides in 234 patients. The IAG, medial joint space (MJS), and MJS difference between the symptomatic and asymptomatic elbow (MJSD) were evaluated by two readers, as well as patient age, gender, sport played, and handedness...
January 10, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29320925/self-perceived-and-actual-motor-competence-in-young-british-children
#14
Michael J Duncan, Victoria Jones, Wesley O'Brien, Lisa M Barnett, Emma L J Eyre
Children's perception of their own motor competence is an important correlate of their actual motor competence. The current study is the first to examine this association in British children and the first to use both product and process measures of actual motor competence. A total of 258 children (139 boys and 119 girls; aged 4 to 7 years, Mean = 5.6, SD = .96) completed measures of self-perceived motor competence using the Pictorial Scale for Perceived Movement Competence in Young Children. Children were classified as "Low," "Medium," or "High" perceived competence based on tertile analysis...
January 1, 2018: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/29317691/realization-of-multiple-orbital-angular-momentum-modes-simultaneously-through-four-dimensional-antenna-arrays
#15
Chao Sun, Shiwen Yang, Yikai Chen, Jixin Guo, Shiwei Qu
Electromagnetic waves carrying orbital angular momentum (OAM) in radio frequency range have drawn great attention owing to its potential applications in increasing communication capacity. In this paper, both single-pole single-throw (SPST) switches and single-pole double-throw (SPDT) switches are designed and implemented. Optimal time sequence allows four-dimensional (4-D) circular antenna array to generate multiple OAM-carrying waves as well as enhance the field intensity of each OAM-carrying wave. A novel experimental platform is developed to measure the phase distribution when the transmitting antenna and the receiving antenna operate at different frequencies...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29315453/a-partial-posterior-bundle-ulnar-collateral-ligament-tear-in-a-10-year-old-boy
#16
Todd P Pierce, Jennifer Kurowicki, Kimona Issa, Anthony Festa, Vincent K McInerney, Anthony J Scillia
Medial-sided elbow pain is becoming more common among pediatric overhead sport athletes. One potential cause of this is a partial or complete tear of the ulnar collateral ligament (UCL). Because the growth plate remains open in many of these athletes, the most common injury experienced is an avulsion at the medial epicondyle. However, although rare, there is a potential to tear the UCL, with the most common tears occurring at the anterior bundle. However, tears to the posterior bundle are quite rare in pediatric patients...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29304957/editorial-commentary-it-s-the-fracture-not-the-fragment-that-causes-the-pain-posteromedial-elbow-impingement-in-baseball-players
#17
EDITORIAL
Shawn W O'Driscoll
Posterior impingement pain in baseball players is typically due to a fractured olecranon osteophyte. Computed tomographic (CT) scanning is the imaging of choice when evaluating posterior or posteromedial elbow pain in athletes who have subjected the elbow to excessive stresses such as occur in overhead throwing and weightlifting. Sometimes the fracture fragment can be so small that it might not be detected on plain radiographs, magnetic resonance imaging, or even at the time of arthroscopy. Symptomatic fractured olecranon osteophytes can be diagnosed clinically with the extension impingement test or arm bar test...
January 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29304255/new-opioid-policy-are-we-throwing-the-baby-out-with-the-bathwater
#18
Mark Sullivan
No abstract text is available yet for this article.
January 2, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29303362/the-demands-of-amputee-soccer-impair-muscular-endurance-and-power-indices-but-not-match-physical-performance
#19
Mário A M Simim, Gustavo R da Mota, Moacir Marocolo, Bruno V C da Silva, Marco Túlio de Mello, Paul S Bradley
We investigated the match demands (distances covered and acute physiological responses) of amputee soccer and its impact on muscular endurance and power. Measures such as heart rate, blood lactate concentration, subjective rating of perceived exertion, and time-motion characteristics were recorded in 16 Brazilian amputee soccer players during matches. Before and after matches, players completed a battery of tests: push-ups, countermovement vertical jump performance, and medicine ball throwing. Small differences were found between the first and second half for the distance covered in total and across various speed categories...
January 5, 2018: Adapted Physical Activity Quarterly: APAQ
https://www.readbyqxmd.com/read/29295698/recent-updates-on-computer-aided-drug-discovery-time-for-a-paradigm-shift
#20
Talambedu Usha, Dhivya Shanmugarajan, Arvind Kumar Goyal, Chinaga Suresh Kumar, Sushil Kumar Middha
Computer aided drug designing (CADD) has gained a wide popularity among biologists and chemists as a part of interdisciplinary drug discovery approach. It plays a vital role in the discovery, design and analysis of drugs in pharmaceutical industry. It is extensively used to reduce cost, time and speed up the early stage development of biologically new active molecules. In the current review we presented a brief review of CADD, merits and demerits, DNA, protein and enzyme as targets, types of CADD: Structure based drug designing (SBDD), ligand based drug designing (LBDD), Pharmacophore based drug designing (PBDD) and fragment based drug designing (FBDD), theory behind the types of CADD and their applications...
January 1, 2018: Current Topics in Medicinal Chemistry
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