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https://www.readbyqxmd.com/read/29793202/itraq-based-quantitative-proteomic-analysis-of-the-earthworm-eisenia-fetida-response-to-escherichia-coli-o157-h7
#1
Xing Wang, Xiaoqin Li, Zhenjun Sun
Soil environment contaminated by Escherichia coli O157:H7 which come from the waste of infected animals. Earthworms can live in the pathogens-polluted soil by their innate immunity. How the proteins of earthworms E. fetida will response to E. coli O157:H7-contaminated-soil still unclear? To identify the defense proteins under E. coli O157:H7 stress, we performed a proteomic analysis of earthworm under E. coli O157:H7 exposure through an iTRAQ technology. In total, we found 283 non-redundant proteins, including fibrinolytic protease 1, lombricine kinase, lysozyme, gelsolin, coelomic cytolytic factor-1, antimicrobial peptide lumbricin-l, lysenin, and et al...
May 21, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29790051/probabilistic-risk-based-pollution-prevention-model-for-a-foundry-a-case-study-of-casting
#2
Souad Ahmed Benromdhane
Hazardous air pollutants from industrial activities have long been associated with serious health effects. Traditional health risk assessment uses point estimates of inhalation concentrations based on standard Gaussian diffusion models with steady-state emission rate assumptions. This traditional approach was criticized because it does not account for variability and thus leading to a potential overestimate of the health risk from the batch processes. To overcome this deficiency, a probabilistic risk assessment model is proposed...
May 22, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29789668/sources-of-household-air-pollution-and-their-association-with-fine-particulate-matter-in-low-income-urban-homes-in-india
#3
Jessica L Elf, Aarti Kinikar, Sandhya Khadse, Vidya Mave, Nishi Suryavanshi, Nikhil Gupte, Vaishali Kulkarni, Sunita Patekar, Priyanka Raichur, Patrick N Breysse, Amita Gupta, Jonathan E Golub
INTRODUCTION: Household air pollution (HAP) is poorly characterized in low-income urban Indian communities. MATERIALS AND METHODS: A questionnaire assessing sources of HAP and 24 h household concentrations of particulate matter less than 2.5 microns in diameter (PM2.5 ) were collected in a sample of low-income homes in Pune, India. RESULTS: In 166 homes, the median 24 h average concentration of PM2.5 was 167 μg/m3 (IQR: 106-294). Although kerosene and wood use were highly prevalent (22% and 25% of homes, respectively), primarily as secondary fuel sources, high PM2...
May 23, 2018: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29788382/colonic-inhibition-of-phosphatase-and-tensin-homolog-increases-colitogenic-bacteria-causing-development-of-colitis-in-il10-mice
#4
Jonathon Mitchell, Su Jin Kim, Georgios Koukos, Alexandra Seelmann, Brendan Veit, Brooke Shepard, Sara Blumer-Schuette, Harland S Winter, Dimitrios Iliopoulos, Charalabos Pothoulakis, Eunok Im, Sang Hoon Rhee
Background: Phosphatase and tensin homolog (Pten) is capable of mediating microbe-induced immune responses in the gut. Thus, Pten deficiency in the intestine accelerates colitis development in Il10-/- mice. As some ambient pollutants inhibit Pten function and exposure to ambient pollutants may increase inflammatory bowel disease (IBD) incidence, it is of interest to examine how Pten inhibition could affect colitis development in genetically susceptible hosts. Methods: With human colonic mucosa biopsies from pediatric ulcerative colitis and non-IBD control subjects, we assessed the mRNA levels of the PTEN gene and the gene involved in IL10 responses...
May 18, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29787974/using-big-data-from-air-quality-monitors-to-evaluate-indoor-pm-2-5-exposure-in-buildings-case-study-in-beijing
#5
JinXing Zuo, Wei Ji, YuJie Ben, Muhammad Azher Hassan, WenHong Fan, Liam Bates, ZhaoMin Dong
Due to time- and expense- consuming of conventional indoor PM2.5 (particulate matter with aerodynamic diameter of less than 2.5 μm) sampling, the sample size in previous studies was generally small, which leaded to high heterogeneity in indoor PM2.5 exposure assessment. Based on 4403 indoor air monitors in Beijing, this study evaluated indoor PM2.5 exposure from 15th March 2016 to 14th March 2017. Indoor PM2.5 concentration in Beijing was estimated to be 38.6 ± 18.4 μg/m3 . Specifically, the concentration in non-heating season was 34...
May 19, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29787898/long-term-effects-of-air-pollution-on-ankle-brachial-index
#6
Siqi Zhang, Kathrin Wolf, Susanne Breitner, Florian Kronenberg, Massimo Stafoggia, Annette Peters, Alexandra Schneider
BACKGROUND: Ankle-brachial index (ABI) has been linked to the risk of cardiovascular events. However, the association between long-term exposure to air pollution and abnormal ABI has not been fully investigated. METHODS: This cross-sectional study involved 4544 participants from the KORA Study (2004-2008) in the region of Augsburg, Germany. Participants' residential annual mean concentrations of particulate matter (PM) and nitrogen dioxide (NO2 ) were predicted with land-use regression models, and the traffic information was collected from geographic information systems...
May 19, 2018: Environment International
https://www.readbyqxmd.com/read/29787794/early-growth-response-gene-1-is-essential-for-urban-particulate-matter-induced-inflammation-and-mucus-hyperproduction-in-airway-epithelium
#7
Feng Xu, Jiaofei Cao, Man Luo, Luanqing Che, Wen Li, Songmin Ying, Zhihua Chen, Huahao Shen
Particulate matter (PM) has been implicated as a risk factor for human airway disorders. However, the biological mechanisms underlying the correlation between PM exposure and adverse airway effects have not yet been fully clarified. The objective of this study was to explore the possible role of early growth response gene 1 (Egr-1) in PM-induced toxic effects in pulmonary inflammation and mucus hyperproduction in vitro and in vivo. Particulate matter exposure induced a rapid Egr-1 expression in human bronchial epithelial (HBE) cells and in mouse lungs...
May 19, 2018: Toxicology Letters
https://www.readbyqxmd.com/read/29786863/acute-ammonia-toxicity-to-the-larvae-glochidia-of-the-tropical-australian-freshwater-mussel-velesunio-spp-using-a-modified-toxicity-test-protocol
#8
Linda S Kleinhenz, Melanie A Trenfield, Thomas J Mooney, Christopher L Humphrey, Rick A van Dam, Dayanthi Nugegoda, Andrew J Harford
Ammonia is recognised as a major pollutant worldwide, originating from natural and anthropogenic sources. Studies have reported that freshwater mussels are amongst the most sensitive taxa to ammonia, but there is a lack of data available on ammonia toxicity for the early life stages of freshwater mussels from tropical regions. This paper reports the modification of a 24-h acute toxicity test protocol for tropical freshwater mussels and application of the test using ammonia. Velesunio spp. from three different sites were used to assess the toxicity of ammonia at a targeted pH of 6...
May 22, 2018: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/29785592/methylmercury-and-diphenyl-diselenide-interactions-in-drosophila-melanogaster-effects-on-development-behavior-and-hg-levels
#9
Mayara B Leão, Paulo C C da Rosa, Caroline Wagner, Thiago H Lugokenski, Cristiane L Dalla Corte
Methylmercury (MeHg) is a highly toxic environmental pollutant which binds with a high affinity to selenol groups. In view of this, seleno-compounds have been investigated as MeHg antidotes. In the present study, we evaluated the effects of the co-exposure to MeHg and the seleno-compound diphenyl diselenide (PhSe)2 on Drosophila melanogaster. We measured the survival rate, developmental survival, locomotor ability, reactive oxygen species (ROS) production, and Hg levels in D. melanogaster exposed to MeHg and/or (PhSe)2 in the food...
May 21, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29785039/extremely-low-frequency-electromagnetic-fields-impair-the-cognitive-and-motor-abilities-of-honey-bees
#10
S Shepherd, M A P Lima, E E Oliveira, S M Sharkh, C W Jackson, P L Newland
Extremely low frequency electromagnetic field (ELF EMF) pollution from overhead powerlines is known to cause biological effects across many phyla, but these effects are poorly understood. Honey bees are important pollinators across the globe and due to their foraging flights are exposed to relatively high levels of ELF EMF in proximity to powerlines. Here we ask how acute exposure to 50 Hz ELF EMFs at levels ranging from 20-100 µT, found at ground level below powerline conductors, to 1000-7000 µT, found within 1 m of the conductors, affects honey bee olfactory learning, flight, foraging activity and feeding...
May 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29783199/inhalational-exposure-to-particulate-matter-air-pollution-alters-the-composition-of-the-gut-microbiome
#11
Ece A Mutlu, Işın Y Comba, Takugo Cho, Phillip A Engen, Cemal Yazıcı, Saul Soberanes, Robert B Hamanaka, Recep Niğdelioğlu, Angelo Y Meliton, Andrew J Ghio, G R Scott Budinger, Gökhan M Mutlu
Recent studies suggest an association between particulate matter (PM) air pollution and gastrointestinal (GI) disease. In addition to direct deposition, PM can be indirectly deposited in oropharynx via mucociliary clearance and upon swallowing of saliva and mucus. Within the GI tract, PM may alter the GI epithelium and gut microbiome. Our goal was to determine the effect of PM on gut microbiota in a murine model of PM exposure via inhalation. C57BL/6 mice were exposed via inhalation to either concentrated ambient particles or filtered air for 8-h per day, 5-days a week, for a total of 3-weeks...
May 18, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29783191/ganga-water-pollution-a-potential-health-threat-to-inhabitants-of-ganga-basin
#12
REVIEW
Sanjay Dwivedi, Seema Mishra, Rudra Deo Tripathi
BACKGROUND: The water quality of Ganga, the largest river in Indian sub-continent and life line to hundreds of million people, has severely deteriorated. Studies have indicated the presence of high level of carcinogenic elements in Ganga water. OBJECTIVES: We performed extensive review of sources and level of organic, inorganic pollution and microbial contamination in Ganga water to evaluate changes in the level of various pollutants in the recent decade in comparison to the past and potential health risk for the population through consumption of toxicant tainted fishes in Ganga basin...
May 18, 2018: Environment International
https://www.readbyqxmd.com/read/29783112/the-neuropeptides-of-asian-freshwater-clam-corbicula-fluminea-as-new-molecular-biomarker-basing-on-the-responses-of-organophosphate-chemicals-exposure
#13
Qi Wang, Xiangsheng Hong, Huihui Chen, Lilai Yuan, Jinmiao Zha
In the present study, to discover new biomarker of Asian freshwater clam (Corbicula fluminea) to assess impact of environmental pollutions, cholecystokinin (CCK), conopressin, and Neuropeptide FF (FFamide) in C. fluminea were selected as potent biomarkers. Therefore, their full-length cDNAs were cloned and characterized to investigate the molecular characteristics and expression patterns of neuropeptides in C. fluminea. According to the sequence analysis, CCK, conopressin, and FFamide encoded proteins of 173, 152, and 90 amino acids, respectively...
May 18, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29783084/organochlorine-pesticides-ocps-and-polychlorinated-biphenyls-pcbs-in-cyprinidae-fish-towards-hints-of-their-arrangements-using-advanced-classification-methods
#14
Snježana Herceg Romanić, Gordana Vuković, Darija Klinčić, Marijana Matek Sarić, Ivan Župan, Davor Antanasijević, Aleksandar Popović
To tackle the ever-present global concern regarding human exposure to persistent organic pollutants (POPs) via food products, this study strived to indicate associations between organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in lake-fish tissue depending on the species and sampling season. Apart from the monitoring initiatives recommended in the Global Monitoring Plan for POPs, the study discussed 7 OCPs and 18 PCB congeners determined in three Cyprinidae species (rudd, carp, and Prussian carp) from Vransko Lake (Croatia), which are widely domesticated and reared as food fish across Europe and Asia...
May 18, 2018: Environmental Research
https://www.readbyqxmd.com/read/29782800/suspect-screening-and-regulatory-databases-a-powerful-combination-to-identify-emerging-micropollutants
#15
Pablo Gago-Ferrero, Agnes Krettek, Stellan Fischer, Karin Wiberg, Lutz Ahrens
This study demonstrates that regulatory databases combined with the latest advances in high resolution mass spectrometry (HRMS) can be efficiently used to prioritize and identify new, potentially hazardous pollutants being discharged into the aquatic environment. Of the approximately 23,000 chemicals registered in the database of the National Swedish Product Register, 160 potential organic micropollutants were prioritized through quantitative knowledge of market availability, quantity used, extent of use on the market, and predicted compartment-specific environmental exposure during usage...
May 21, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29781104/cavities-shield-birds-from-effects-of-artificial-light-at-night-on-sleep
#16
Thomas Raap, Rianne Pinxten, Marcel Eens
Light pollution is an ever increasing worldwide problem disrupting animal behavior. Artificial light at night (ALAN) has been shown to affect sleep in wild birds. Even cavity-nesting bird species may be affected when sleeping inside their cavity. Correlational studies suggest that light from outside the cavity/nest box, for example from street lights, may affect sleep. We used an experimental design to study to what extent nest boxes shield animals from effects of ALAN on sleep. We recorded individual sleep behavior of free-living great tits (Parus major) that were roosting in dark nest boxes and exposed their nest box entrance to ALAN the following night (1...
May 20, 2018: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29781095/gasoline-exhaust-damages-spermatogenesis-through-downregulating-%C3%AE-6-integrin-and-%C3%AE-1-integrin-in-the-rat-model
#17
L Luo, E Li, S Zhao, J Wang, Z Zhu, Y Liu, J Luo, Z Zhao
The health influence of air pollution has been an international public health concern. Increasing evidence has suggested that air pollution has been associated with decreased sperm quality. However, the underlying molecular mechanisms are still not fully elucidated. We aimed to verify whether gasoline exhaust leads to reproductive impairment by injuring spermatogonial stem cells and explore its underlying molecular mechanism. Twenty male Sprague-Dawley rats were randomly divided into two groups: the exposure group (n = 10) and the control group (n = 10)...
May 20, 2018: Andrologia
https://www.readbyqxmd.com/read/29780828/effect-of-formaldehyde-on-human-middle-ear-epithelial-cells
#18
Shin Hye Kim, Ji-Woong Choi, Myung-Whan Suh, Jun Ho Lee, Seung-Ha Oh, Jae-Jun Song, Moo Kyun Park
Formaldehyde (FA) is a familiar indoor air pollutant found in everything from cosmetics to clothing, but its impact on the middle ear is unknown. This study investigated whether FA causes cytotoxicity, inflammation, or induction of apoptosis in human middle ear epithelial cells (HMEECs). Cell viability was investigated using the trypan blue assay and a cell counting kit (CCK-8) in HMEECs treated with FA for 4 or 24 h. The expression of genes encoding the inflammatory cytokine tumor necrosis factor alpha (TNF- α ) and mucin (MUC5AC) was analyzed using RT-PCR...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29780445/a-comparison-of-simulated-and-field-derived-leaf-area-index-lai-and-canopy-height-values-from-four-forest-complexes-in-the-southeastern-usa
#19
John S Iiames, Ellen Cooter, Donna Schwede, Jimmy Williams
Vegetative leaf area is a critical input to models that simulate human and ecosystem exposure to atmospheric pollutants. Leaf area index (LAI) can be measured in the field or numerically simulated, but all contain some inherent uncertainty that is passed to the exposure assessments that use them. LAI estimates for minimally managed or natural forest stands can be particularly difficult to develop as a result of interspecies competition, age and spatial distribution. Satellite-based LAI estimates hold promise for retrospective analyses, but we must continue to rely on numerical models for alternative management analysis...
2018: Forests
https://www.readbyqxmd.com/read/29778967/association-between-long-term-exposure-to-ambient-air-pollution-and-diabetes-mortality-in-the-us
#20
Chris C Lim, Richard B Hayes, Jiyoung Ahn, Yongzhao Shao, Debra T Silverman, Rena R Jones, Cynthia Garcia, George D Thurston
OBJECTIVE: Recent mechanistic and epidemiological evidence implicates air pollution as a potential risk factor for diabetes; however, mortality risks have not been evaluated in a large US cohort assessing exposures to multiple pollutants with detailed consideration of personal risk factors for diabetes. RESEARCH DESIGN AND METHODS: We assessed the effects of long-term ambient air pollution exposures on diabetes mortality in the NIH-AARP Diet and Health Study, a cohort of approximately a half million subjects across the contiguous U...
May 17, 2018: Environmental Research
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