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depression during adolescence

Karina Quevedo, Rowena Ng, Hannah Scott, Garry Smyda, Jennifer H Pfeifer, Sandra Malone
Maltreatment is associated with chronic depression, high negative self-attributions, and lifetime psychopathology. Adolescence is a sensitive period for the formation of self-concept. Identifying neurobiomarkers of self-processing in depressed adolescents with and without maltreatment may parse the effects of trauma and depression on self-development and chronic psychopathology. Depressed adolescents (n = 86) maltreated due to omission (DO, n = 13) or commission (DCM, n = 28) or without maltreatment (DC, n = 45), and HCs (HC, n = 37) appraised positive and negative self-descriptors in the scanner...
October 20, 2016: Development and Psychopathology
Shannon Dorsey, Katie A McLaughlin, Suzanne E U Kerns, Julie P Harrison, Hilary K Lambert, Ernestine C Briggs, Julia Revillion Cox, Lisa Amaya-Jackson
Child and adolescent trauma exposure is prevalent, with trauma exposure-related symptoms, including posttraumatic stress, depressive, and anxiety symptoms often causing substantial impairment. This article updates the evidence base on psychosocial treatments for child and adolescent trauma exposure completed for this journal by Silverman et al. (2008). For this review, we focus on 37 studies conducted during the seven years since the last review. Treatments are grouped by overall treatment family (e.g., cognitive behavioral therapy), treatment modality (e...
October 19, 2016: Journal of Clinical Child and Adolescent Psychology
Hang Xu, Yu Zhang, Fan Zhang, San-Na Yuan, Feng Shao, Weiwen Wang
Early stress is a significant risk factor for the onset of mood disorders such as depression during adulthood. Impairments in cognitive flexibility mediated by prefrontal cortex (PFC) dysfunction are increasingly recognized as important etiological and pathological factors in the development of depression. Our previous study demonstrated that social defeat stress during early adolescence produced delayed deficits in cognitive flexibility in adult mice. The potential molecular mechanisms underlying these long-term consequences remain unclear...
2016: Frontiers in Molecular Neuroscience
Venu Duddu, Abdulhakim Rhouma, Masood Qureshi, Imran Bashir Chaudhry, Terry Drake, Altaf Sumra, Nusrat Husain
Aims and method The need for an age-appropriate in-patient service for 16- to 17-year-olds led to the development of a 6-bed acute admissions unit in a non-metropolitan county in the UK. We provide a descriptive evaluation of the first 2 years of its operation. All admissions from April 2010 to March 2012 were reviewed, clinical details systematically recorded and descriptively analysed. Results Ninety-seven young people were admitted during this period (a third were compulsorily detained under the Mental Health Act 1983)...
October 2016: BJPsych Bulletin
Sonja E Siennick, Alex O Widdowson, Mathew K Woessner, Mark E Feinberg, Richard L Spoth
PURPOSE: Depressive symptoms during adolescence are positively associated with peer-related beliefs, perceptions, and experiences that are known risk factors for substance misuse. These same risk factors are targeted by many universal substance misuse prevention programs. This study examined whether a multicomponent universal substance misuse intervention for middle schoolers reduced the associations between depressive symptoms, these risk factors, and substance misuse. METHODS: The study used data from a place-randomized trial of the Promoting School-Community-University Partnerships to Enhance Resilience model for delivery of evidence-based substance misuse programs for middle schoolers...
October 14, 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
Lauren B Alloy, Jessica L Hamilton, Elissa J Hamlat, Lyn Y Abramson
Adolescence marks the emergence of sex differences in internalizing symptoms and disorders, with girls at increased risk for depression and anxiety during the pubertal transition. However, the mechanisms through which puberty confers risk for internalizing psychopathology for girls, but not boys, remain unclear. We examined two pubertal indicators (pubertal status and timing) as predictors of the development of emotion regulation styles (rumination and emotional clarity) and depressive and anxiety symptoms and disorders in a three-wave study of 314 adolescents...
September 2016: Clinical Psychological Science
Maria Kovacs, Lauren M Bylsma, Ilya Yaroslavsky, Jonathan Rottenberg, Charles J George, Enikő Kiss, Kitti Halas, István Benák, Ildiko Baji, Ágnes Vetro, Krisztina Kapornai
While hedonic capacity is diminished during clinical depression, it is unclear whether that deficit constitutes a risk factor and/or persists after depression episodes remit. To examine these issues, adolescents with current/past major depression (probands; n=218), never depressed biological siblings of probands (n=207), and emotionally-well controls (n=183) were exposed to several positively valenced probes. Across baseline and hedonic probe conditions, controls consistently reported higher levels of positive affect than high-risk siblings, and siblings reported higher levels of positive affect than probands (remitted and depressed probands' reports were similar)...
July 2016: Clinical Psychological Science
Siyang Yan, Amanda C Kentner
Exposure to painful procedures and/or stressors during the early neonatal period can reprogram the underlying neurocircuitry involved in nociception and neuropathic pain perception. The reprogramming of these systems can result in an enduring elevation in sensitivity towards mechanical and thermal stimuli. Recent evidence suggests that exposure to mild inflammatory mediators during the neonatal period can induce similar pain responses in both adolescent and adult rats. Therefore, we sought to profile changes in the expression of several genes across brain areas involved in the active modulation of nociception and neuropathic pain using a well-recognized model of neonatal inflammation...
October 11, 2016: Brain, Behavior, and Immunity
Joshua Hayward, Felice N Jacka, Helen Skouteris, Lynne Millar, Claudia Strugnell, Boyd A Swinburn, Steven Allender
OBJECTIVE: Depression affects many Australian adolescents. Research points to the potential of lifestyle improvement for the population-level prevention of mental disorders. However, most studies examine single relationships without considering the combined contribution of lifestyle factors to variance in depression. This study examined associations between adolescent diet, physical activity and screen time behaviours and depressive symptomatology. METHODS: A cross-sectional sample of year 8 and 10 students was recruited from 23 participating schools in 18 Victorian communities...
October 12, 2016: Australian and New Zealand Journal of Psychiatry
Kalsea J Koss, E Mark Cummings, Patrick T Davies, Susan Hetzel, Dante Cicchetti
Depressive symptoms are prevalent and rise during adolescence. The present study is a prospective investigation of environmental and genetic factors that contribute to the growth in depressive symptoms and the frequency of heightened symptoms during adolescence. Participants included 206 mother-father-adolescent triads (M age at Time 1 = 13.06 years, SD = .51, 52% female). Harsh parenting was observationally assessed during a family conflict paradigm. DNA was extracted from saliva samples and genotyped for the 5-HTTLPR and BDNF Val66Met polymorphisms...
October 13, 2016: Journal of Clinical Child and Adolescent Psychology
Stephanie H Cook, Pamela Valera, Benjamin J Calebs, Patrick A Wilson
Objective: The present study examined the moderating effect of adult attachment on the association between childhood traumatic experiences, (i.e., physical abuse, emotional abuse, emotional neglect, and being bullied), age of childhood traumatic experience, and young adult depression symptoms among young Black gay and bisexual men (YBGBM). Method: Self-report measures of attachment, childhood traumatic experiences, and depression symptoms were collected from a community-based sample of YBGBM living in New York City (n = 228)...
October 13, 2016: Cultural Diversity & Ethnic Minority Psychology
Lauren P Shapiro, Ryan G Parsons, Anthony J Koleske, Shannon L Gourley
The prevalence of depression, anxiety, schizophrenia, and drug and alcohol use disorders peaks during adolescence. Further, up to 50% of "adult" mental health disorders emerge in adolescence. During adolescence, the prefrontal cortex (PFC) undergoes dramatic structural reorganization, in which dendritic spines and synapses are refined, pruned, and stabilized. Understanding the molecular mechanisms that underlie these processes should help to identify factors that influence the development of psychiatric illness...
October 13, 2016: Journal of Neuroscience Research
Alan S Brown, David Gyllenberg, Heli Malm, Ian W McKeague, Susanna Hinkka-Yli-Salomäki, Miia Artama, Mika Gissler, Keely Cheslack-Postava, Myrna M Weissman, Jay A Gingrich, Andre Sourander
Importance: Speech/language, scholastic, and motor disorders are common in children. It is unknown whether exposure to selective serotonin reuptake inhibitors (SSRIs) during pregnancy influences susceptibility to these disorders. Objective: To examine whether SSRI exposure during pregnancy is associated with speech/language, scholastic, and motor disorders in offspring up to early adolescence. Design, Setting, and Participants: This prospective birth cohort study examined national population-based register data in Finland from 1996 to 2010...
October 12, 2016: JAMA Psychiatry
Erin C Dunn, Kristen Nishimi, Abigail Powers, Bekh Bradley
BACKGROUND: Trauma exposure is a known risk factor for psychopathology. However, the impact of the developmental timing of exposure remains unclear. This study examined the effect of age at first trauma exposure on levels of adult depressive and posttraumatic stress disorder (PTSD) symptoms. METHODS: Lifetime trauma exposure (including age at first exposure and frequency), current psychiatric symptoms, and sociodemographic information were collected during interviews with adults participating in a study at a public urban hospital in Atlanta, GA...
September 13, 2016: Journal of Psychiatric Research
L S Resende, C E Amaral, R B S Soares, A S Alves, L Alves-Dos-Santos, L R G Britto, S Chiavegatto
MAX is a conserved constitutive small phosphoprotein from a network of transcription factors that are extensively studied in tumorigenesis and whose functions affect cell proliferation, differentiation and death. Inspired by its higher expression during development and in regions involved in emotional behaviors, we hypothesized its involvement in cerebral changes caused by early-life stress. We studied the effects of repeated social stress during adolescence on behaviors and on MAX and its putative partner MYC...
October 11, 2016: Translational Psychiatry
Robin E Gearing, Kathryne B Brewer, Irfan Mian, Kiara Moore, Prudence Fisher, Jane Hamilton, James Mandiberg
AIM: The timely identification and treatment of psychosis are increasingly the focus of early interventions, with research targeting the initial high-risk period in the months following first-episode hospitalization. Ongoing treatment after stabilization is also essential in the years following a first-episode psychosis (FEP), but has received less research attention. In this study, variables that could impact continued psychiatric service utilization by adolescents following their FEP and temporal patterns in service utilization are examined...
October 11, 2016: Early Intervention in Psychiatry
Joyce Ho, Marya E Corden, Lauren Caccamo, Kathryn Noth Tomasino, Jenna Duffecy, Mark Begale, David C Mohr
BACKGROUND: Depression during adolescence is common but can be prevented. Behavioral intervention technologies (BITs) designed to prevent depression in adolescence, especially standalone web-based interventions, have shown mixed outcomes, likely due to poor intervention adherence. BIT research involving adults has shown that the presence of coaches or peers promotes intervention use. Developmentally, adolescence is a time when peer-based social relationships take precedence. This study examines whether peer-networked support may promote adherence to BITs in this age group...
November 2016: Internet Interventions: the Application of Information Technology in Mental and Behavioural Health
Jillian J Turanovic, Travis C Pratt
Native American youth are at an elevated risk of violent victimization. And because of their vulnerable position in society, they may also be at risk of experiencing a host of adverse consequences as a result of being victimized. Accordingly, using a subsample of 558 Native American youth and two waves of data from the National Longitudinal Study of Adolescent to Adult Health (49.8 % female; 12-19 years at Wave I; 19-26 years at Wave III), we examined the effects of violent victimization during adolescence on a range of outcomes in early adulthood (poor health, depressive symptoms, suicidality, financial hardship, violent and property offending, alcohol problems, hard drug use, and marijuana use)...
October 7, 2016: Journal of Youth and Adolescence
Colm G Connolly, Tiffany C Ho, Eva Henje Blom, Kaja Z LeWinn, Matthew D Sacchet, Olga Tymofiyeva, Alan N Simmons, Tony T Yang
BACKGROUND: The incidence of major depressive disorder (MDD) rises during adolescence, yet the neural mechanisms of MDD during this key developmental period are unclear. Altered amygdala resting-state functional connectivity (RSFC) has been associated with both adolescent and adult MDD, as well as symptom improvement in response to treatment in adults. However, no study to date has examined whether amygdala RSFC is associated with changes in depressive symptom severity in adolescents...
September 23, 2016: Journal of Affective Disorders
Monica Kirkpatrick Johnson, Jeremy Staff, Megan E Patrick, John E Schulenberg
This study examines the impact of the "Great Recession" (from December 2007 to June 2009) on 8th and 10th graders in the USA, using annual nationally representative data from the Monitoring the Future study. Historical changes in youth adjustment (self-esteem, depressed mood, risk taking, aggression and property crime), school achievement (grade point average [GPA], time spent on homework and educational expectations) and structured and unstructured activities (volunteering, employment, sports and evenings out for fun) were examined between 1991 and 2014...
October 6, 2016: International Journal of Psychology: Journal International de Psychologie
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