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depression during adolescence

G M Khandaker, J Stochl, S Zammit, I Goodyer, G Lewis, P B Jones
BACKGROUND: To identify developmental sub-groups of depressive symptoms during the second decade of life, a critical period of brain development, using data from a prospective birth cohort. To test whether childhood intelligence and inflammatory markers are associated with subsequent persistent depressive symptoms. METHODS: IQ, a proxy for neurodevelopment, was measured at age 8 years. Interleukin 6 (IL-6) and C-reactive protein, typical inflammatory markers, were measured at age 9 years...
November 15, 2017: Psychological Medicine
Anne A E Thorup, Thomas Munk Laursen, Trine Munk-Olsen, Anne Ranning, Preben Bo Mortensen, Kerstin J Plessen, Merete Nordentoft
BACKGROUND: Offspring of parents with severe mental illness (SMI: schizophrenia, bipolar disorder or major depressive disorder) have an increased risk of developing mental disorder themselves. In childhood they may have neurodevelopmental delays, cognitive deficits and social adversities. We aimed to investigate if these individuals are more at risk of being diagnosed with a mental disorder during childhood/adolescence in a national sample. METHODS: By linking Danish registers we established a cohort consisting of all persons born to parents with SMI with those born to parents without SMI serving as a reference group...
November 10, 2017: Schizophrenia Research
Vanessa Polina Pereira Costa, Marcos Britto Correa, Marília Leão Goettems, Ricardo Tavares Pinheiro, Flávio Fernando Demarco
Exposure to maternal symptoms of depression/anxiety has long-term negative consequences for child development, regardless of the contextual risk. The objective of this study was to investigate the relationship of the symptomatology of persistent maternal depression and anxiety with child dental fear. This study was nested in a cohort of adolescent mothers in southern Brazil. Symptomatology of maternal depression and anxiety was assessed during pregnancy and postpartum, when the mothers' children were 24-36 months old, using Beck Depression Inventory and Beck Anxiety Inventory...
November 6, 2017: Brazilian Oral Research
Angelie Singh, Caroline Trumpff, Jeanine Genkinger, Alida Davis, Marisa Spann, Elizabeth Werner, Catherine Monk
Adolescent pregnant women are at greater risk for nutritional deficits, stress, and depression than their adult counterparts, and these risk factors for adverse pregnancy outcomes are likely interrelated. This study evaluated the prevalence of nutritional deficits in pregnant teenagers and assessed the associations among micronutrient dietary intake, stress, and depression. One hundred and eight pregnant Latina adolescents completed an Automated Self-Administered 24-hour dietary recall (ASA24) in the 2nd trimester...
November 4, 2017: Nutrients
Inken Kirschbaum, Joana Straub, Stephanie Gest, Martin Holtmann, Tanja Legenbauer
Chronotherapeutics are well established for the treatment of depression and associated sleeping problems in adults. However, effects are still understudied in adolescents. Two pilot studies highlighted the crucial role of sleep when it comes to the treatment of depression, by means of chronotherapeutics, in adolescents. The aim of the present study was to investigate the role of adjunctive wake therapy (WT) in addition to bright light therapy (BLT) with respect to sleep behaviors. In the present study, 62 depressed inpatients (aged 13-18 years; diagnosed with Beck Depression Inventory Revision) were randomly assigned to two groups: BLT only (BLT-group) and a combination of BLT and WT (COMB-group)...
November 7, 2017: Chronobiology International
Huali Wu, Qiongzhen Liu, Praveen Kumar Kalavagunta, Qiaoling Huang, Wenting Lv, Xiaohong An, Haijuan Chen, Tao Wang, Rakotomalala Manda Heriniaina, Tong Qiao, Jing Shang
Recent evidence has established that consumption of High-fat diet (HFD)-induced obesity is associated with deficits in hippocampus-dependent memory/learning and mood states. Nevertheless the link between obesity and emotional disorders still remains to be elucidated. This issue is of particular interest during adolescence, which is important period for shaping learning/memory and mood regulation that can be sensitive to the detrimental effects of HFD. Our present study is focused to investigate behavioral and metabolic influences of short-term HFD intake in adolescent C57BL/6 mice...
November 3, 2017: Metabolic Brain Disease
Bonnie Klimes-Dougan, Melinda Westlund Schreiner, Michelle Thai, Meredith Gunlicks-Stoessel, Kristina Reigstad, Kathryn R Cullen
OBJECTIVE: Typically, about 30 to 50% of adolescents with depression fail to respond to evidence-based treatments, including antidepressant medications such as selective serotonin reuptake inhibitors (SSRIs). Efforts for identifying predictors and moderators of treatment response are needed to begin to address critical questions relevant to personalized care in adolescent depression. In this pilot study, we aim to identify biological predictors of response to antidepressant treatment...
November 1, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
Yael Perry, Aliza Werner-Seidler, Alison Calear, Andrew Mackinnon, Catherine King, Jan Scott, Sally Merry, Theresa Fleming, Karolina Stasiak, Helen Christensen, Philip J Batterham
BACKGROUND: Depression often emerges for the first time during adolescence. There is accumulating evidence that universal depression prevention programs may have the capacity to reduce the impact of depression when delivered in the school environment. OBJECTIVE: This trial investigated the effectiveness of SPARX-R, a gamified online cognitive behavior therapy intervention for the prevention of depression relative to an attention-matched control intervention delivered to students prior to facing a significant stressor-final secondary school exams...
November 2, 2017: Journal of Medical Internet Research
E Janssen, S Spilka, F Beck
BACKGROUND: The aim of this study was to describe potential associations between suicidal behaviors and psychoactive substance uses among adolescents. METHODS: A cross-sectional, national survey representative of adolescents aged 17, living in continental France, was conducted in 2014. A total of 22,023 adolescents answered an anonymous, self-administered questionnaire about their health and their use of psychoactive substances. Suicidal risk was assessed by means of a 4-level indicator [1...
November 2017: Revue D'épidémiologie et de Santé Publique
Bridget L Callaghan, Orwa Dandash, Julian G Simmons, Orli Schwartz, Michelle L Byrne, Lisa Sheeber, Nicholas B Allen, Sarah Whittle
OBJECTIVE: The parent-adolescent relationship is an important predictor of adolescent mental health, especially depressive disorders. This relationship is constructed in the context of maturing emotion neurobiology and could help shape such neurobiology in ways that are important for current and future mental health. Amygdala resting-state functional networks have been linked to depression, but whether such resting connectivity is associated with parent affective behaviors or acts as a salient mediator between parenting and risk for depressive disorder is unknown...
November 2017: Journal of the American Academy of Child and Adolescent Psychiatry
Sherika Hill, Lilly Shanahan, E Jane Costello, William Copeland
OBJECTIVE: To identify risk profiles associated with patterns of problematic cannabis use in early adulthood. METHOD: Data came from 1,229 participants in the Great Smoky Mountains Study, a prospective 20-year cohort study from 1993 to 2015 that is representative of western North Carolina with yearly assessments conducted from ages 9 and 16 years, and assessments at ages 19, 21, 26, and 30 years. Patterns of problematic cannabis use (i.e., DSM-5 cannabis use disorder or daily use) in early adulthood included the following: nonproblematic use in late adolescence (ages 19-21) and early adulthood (ages 26-30); limited problematic use in late adolescence only; persistent problematic use in late adolescence and early adulthood; and delayed problematic use in early adulthood only...
November 2017: Journal of the American Academy of Child and Adolescent Psychiatry
Andrew Gardner, Sue M Cotton, Kelly Allott, Kate M Filia, Robert Hester, Eóin Killackey
AIM: People with psychosis are at risk of social exclusion. Research is needed in this area due to the lack of direct measurement of social inclusion, which becomes salient in adolescence and is relevant to first-episode psychosis (FEP; the onset of which typically occurs during or shortly after adolescence). Social inclusion may be impacted by impaired social cognition and social functioning, which are related features observed in psychosis. The aim of this study was to explore interrelationship(s) between social cognition, social functioning and social inclusion in FEP while controlling for symptomatology (positive, negative and depressive symptoms) and demographic characteristics...
October 27, 2017: Early Intervention in Psychiatry
S Sfelinioti, M Livaditis
Family problems are considered to be the main risk factor leading to the development of behavi oural problems during childhood and adolescence as well. A well documented fact in the current literature is that psychopathology of any kind in parents may influence behaviour, personality and appearance of psychopathology in their children. The permanent interaction between children's psychopathology or any kind of developmental disorder on one hand and parental psychopathology on the other, is considered to be one of the most important fields of research during the last decades...
July 2017: Psychiatrikē, Psychiatriki
B Wang, L G Brueni, C Isensee, T Meyer, N Bock, U Ravens-Sieberer, F Klasen, R Schlack, A Becker, A Rothenberger
We examined whether there are certain dysregulation profile trajectories in childhood that may predict an elevated risk for mental disorders in later adolescence. Participants (N = 554) were drawn from a representative community sample of German children, 7-11 years old, who were followed over four measurement points (baseline, 1, 2 and 6 years later). Dysregulation profile, derived from the parent report of the Strengths and Difficulties Questionnaire, was measured at the first three measurement points, while symptoms of attention deficit hyperactivity disorder (ADHD), anxiety and depression were assessed at the fourth measurement point...
October 25, 2017: European Child & Adolescent Psychiatry
Ehtramolsadat Sahafi, Maghsoud Peeri, Mir-Jamal Hosseini, Mohammad Ali Azarbyjani
Early life stress (ELS) is known as a risk factor for the development of depression and its associated comorbidities, such as cardiomyopathy in depressed patients. Mitochondrial dysfunction plays a critical role in the pathophysiology of depression and cardiovascular diseases. Evidence indicates that regular physical activity has therapeutic effects on both mood and cardiovascular disorders. Therefore, the voluntary running wheel exercise (RW) during adolescence may be able to attenuate the negative impact of maternal separation stress (MS) as a valid animal model of depression on the behavior and cardiac mitochondrial function of adult rats...
January 1, 2018: Physiology & Behavior
Sandeep Grover, Nidhi Chauhan, Akhilesh Sharma, Subho Chakrabarti, Ajit Avasthi
AIM: To study the symptom profile of catatonia in children and adolescents. METHODOLOGY: Treatment records of all the inpatients aged (≤19 years) were reviewed for the period January 2005 to January 2017. Patients with catatonia (diagnosed as having at least two symptoms as per the Bush Francis Catatonia Rating scale) were included. RESULTS: During the study period, data was available for 52 children and adolescent. The mean age of the sample was 16...
October 2017: Asian Journal of Psychiatry
M Kellner, T Porseryd, I Porsch-Hällström, B Borg, C Roufidou, K H Olsén
Selective Serotonin re-uptake inhibitors (SSRIs) are a class of psychotropic drugs used to treat depression in both adolescents and pregnant or breast-feeding mothers as well as in the general population. Recent research on rodents points to long-lasting behavioural effects of pre- and perinatal exposure to SSRIs which last into adulthood. In fish however, studies on effects of developmental exposure to SSRIs appears to be non-existent. In order to study effects of developmental SSRI exposure in fish, three-spine sticklebacks were exposed to 1...
October 23, 2017: Ecotoxicology
Hannah L Schacter, Jaana Juvonen
Past research indicates that depressed adolescents experience increased risk for peer victimization. Less is known about the conditions under which depressive symptoms predict social vulnerability and the mechanism underlying such links. The current study considers a) characterological self-blaming attributions as a social cognitive mechanism accounting for links between depressive symptoms and victimization across the first two years of middle school and b) the potential moderating role of friends' level of depressive symptoms...
July 2017: Journal of Applied Developmental Psychology
Syudo Yamasaki, Satoshi Usami, Ryo Sasaki, Shinsuke Koike, Shuntaro Ando, Yuko Kitagawa, Misato Matamura, Masako Fukushima, Hiromi Yonehara, Jerome Clifford Foo, Atsushi Nishida, Tsukasa Sasaki
BACKGROUND: Recent cross-sectional studies suggest that psychotic-like experiences (PLEs) are associated with depression and anxiety in adolescents. While longitudinal studies have observed that adolescents suffer more severe symptoms of depression/anxiety when PLEs persist, it remains unclear whether depression/anxiety worsens or improves with PLE emergence or remission, respectively. In this prospective school-based study, we investigated the association between longitudinal changes in depression/anxiety and one-year PLE trajectories in adolescence...
October 18, 2017: Schizophrenia Research
Raquel Nogueira Avelar E Silva, Daphne van de Bongardt, Laura Baams, Hein Raat
PURPOSE: Assessing bidirectional longitudinal associations between early sexual behaviors (≤16.0 years) and psychological well-being (global self-esteem, physical self-esteem, depression) among 716 adolescents, and the direct and buffering effect of parent-adolescent relationship quality. METHODS: We used data from Project STARS (Studies on Trajectories of Adolescent Relationships and Sexuality), a longitudinal study on adolescent sexual development in the Netherlands...
October 17, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
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