Emma Bränn, Yufeng Chen, Huan Song, Krisztina D László, Brian M D'Onofrio, Elgeta Hysaj, Catarina Almqvist, Henrik Larsson, Paul Lichtenstein, Unnur A Valdimarsdottir, Donghao Lu
Although major depression, characterized by a pro-inflammatory profile, genetically overlap with autoimmune disease (AD) and the perinatal period involve immune system adaptations and AD symptom alterations, the bidirectional link between perinatal depression (PND) and AD is largely unexplored. Hence, the objective of this study was to investigate the bidirectional association between PND and AD. Using nationwide Swedish population and health registers, we conducted a nested case-control study and a matched cohort study...
January 9, 2024: Molecular Psychiatry