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Postpartum psychiatric disorders

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https://www.readbyqxmd.com/read/27914245/perinatal-hypothalamic-pituitary-adrenal-axis-regulation-among-women-with-eating-disorders-and-their-infants
#1
A Easter, E Taborelli, A Bye, P A Zunszain, C M Pariante, J Treasure, U Schmidt, N Micali
BACKGROUND: Psychiatric illness is associated with heightened hypothalamic-pituitary-adrenal (HPA) axis activity during pregnancy which may have long term effects on infant stress regulation. HPA axis regulation has not previously been investigated in women with eating disorders (ED) or their infants during the perinatal period. METHODS: Women were recruited to a prospective longitudinal study in three groups: 1) current or active ED (C-ED=31), 2) past ED (P-ED=29) and healthy control (HC=57)...
November 11, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27829570/a-multi-state-analysis-of-postpartum-readmissions-in-the-united-states
#2
Mark A Clapp, Sarah E Little, Jie Zheng, Julian N Robinson
BACKGROUND: Readmission rates are used as a quality metric in medical and surgical specialties; however, little is known about obstetrics readmissions. OBJECTIVE: Our goals for this study were to describe the trends in postpartum readmissions over time; to characterize the common indications and associated diagnoses for readmissions; and to determine maternal, delivery, and hospital characteristics that may be associated with readmission. STUDY DESIGN: Postpartum readmissions occurring within the first 6 weeks after delivery in California, Florida, and New York were identified between 2004 and 2011 in State Inpatient Databases...
July 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27824771/maternal-deaths-from-suicide-and-overdose-in-colorado-2004-2012
#3
Torri D Metz, Polina Rovner, M Camille Hoffman, Amanda A Allshouse, Krista M Beckwith, Ingrid A Binswanger
OBJECTIVE: To ascertain demographic and clinical characteristics of maternal deaths from self-harm (accidental overdose or suicide) to identify opportunities for prevention. METHODS: We report a case series of pregnancy-associated deaths resulting from self-harm in the state of Colorado between 2004 and 2012. Self-harm deaths were identified from several sources, including death certificates. Birth and death certificates along with coroner, prenatal care, and delivery hospitalization records were abstracted...
December 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27810668/risk-factors-for-suicide-attempt-in-pregnancy-and-the-post-partum-period-in-women-with-serious-mental-illnesses
#4
Florence Gressier, Virginie Guillard, Odile Cazas, Bruno Falissard, Nine M-C Glangeaud-Freudenthal, Anne-Laure Sutter-Dallay
Suicide is a major public health concern worldwide, and mental disorders have been identified as a main risk factor. Suicide is also one of the leading causes of perinatal maternal mortality, but very few studies have focused on suicide attempts (SA) in the perinatal period. This work aims to assess risk factors associated with SA in pregnancy and in the post-partum period in women with mental health disorders. Women (n = 1439) with psychiatric disorders jointly admitted with their infant to 16 psychiatric Mother-Baby Units over 10 years (2001-2010) were assessed retrospectively for the occurrence of SA in pregnancy or the postpartum period...
October 13, 2016: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/27754485/perinatal-psychiatric-episodes-a-population-based-study-on-treatment-incidence-and-prevalence
#5
T Munk-Olsen, M L Maegbaek, B M Johannsen, X Liu, L M Howard, A di Florio, V Bergink, S Meltzer-Brody
Perinatal psychiatric episodes comprise various disorders and symptom severity, which are diagnosed and treated in multiple treatment settings. To date, no studies have quantified the incidence and prevalence of perinatal psychiatric episodes treated in primary and secondary care, which we aimed to do in the present study. We designed a descriptive prospective study and included information from Danish population registers to study first-time ever and recurrent psychiatric episodes during the perinatal period, including treatment at psychiatric facilities and general practitioners (GPs)...
October 18, 2016: Translational Psychiatry
https://www.readbyqxmd.com/read/27754482/predicting-early-psychiatric-readmission-with-natural-language-processing-of-narrative-discharge-summaries
#6
A Rumshisky, M Ghassemi, T Naumann, P Szolovits, V M Castro, T H McCoy, R H Perlis
The ability to predict psychiatric readmission would facilitate the development of interventions to reduce this risk, a major driver of psychiatric health-care costs. The symptoms or characteristics of illness course necessary to develop reliable predictors are not available in coded billing data, but may be present in narrative electronic health record (EHR) discharge summaries. We identified a cohort of individuals admitted to a psychiatric inpatient unit between 1994 and 2012 with a principal diagnosis of major depressive disorder, and extracted inpatient psychiatric discharge narrative notes...
October 18, 2016: Translational Psychiatry
https://www.readbyqxmd.com/read/27738382/maternal-and-fetal-outcomes-after-lamotrigine-use-in-pregnancy-a-retrospective-analysis-from-an-urban-maternal-mental-health-centre-in-new-zealand
#7
Chandni Prakash, Susan Hatters-Friedman, Charmian Moller-Olsen, Abigail North
INTRODUCTION: Pregnancy is a vulnerable period for recurrence of bipolar disorder. Discontinuation of mood stabilisers during pregnancy and the postpartum period can significantly increase the risk of recurrence of bipolar disorder. Lamotrigine is an anti-epileptic drug that has been approved for the maintenance treatment of bipolar disorder. Epilepsy literature has indicated that lamotrigine has a reassuring safety profile in pregnancy but there is little information on its effectiveness and safety in pregnant women with mental disorders...
August 15, 2016: Psychopharmacology Bulletin
https://www.readbyqxmd.com/read/27728876/a-pharmacological-mouse-model-suggests-a-novel-risk-pathway-for-postpartum-psychosis
#8
Trevor Humby, Ellen S Cross, Lauren Messer, Silvia Guerrero, William Davies
Postpartum psychosis (PP) is a severe psychiatric disorder affecting a small proportion of new mothers shortly after childbirth. The molecular pathophysiology underlying the disorder is currently poorly understood, and there are no amenable animal models for the condition; maternal deficiency for the enzyme steroid sulfatase has been proposed as a potential risk mechanism. Here we show that inhibition of steroid sulfatase with 667-COUMATE (10mg/kg p.o.) in new mouse mothers results in behavioural abnormalities that can be partially alleviated by the administration of the clinically-efficacious antipsychotic ziprasidone (0...
September 28, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27703098/cognitive-dysfunction-and-associated-behaviour-problems-in-postpartum-women-a-study-from-north-india
#9
P S Meena, R Soni, M Jain, C S Jilowa, Omprakash
OBJECTIVES: During and after childbirth women undergo tremendous psychological and biological changes. These biological changes, along with the stress of assuming the new role of mother, make postpartum women vulnerable to various psychiatric disorders including cognitive dysfunction, depression, and anxiety. Such problems are under-reported as they are difficult to identify, especially by caregivers who are more focused on the newborn. The present study aimed to evaluate the prevalence of behaviour problems and cognitive dysfunction during the postpartum period...
September 2016: East Asian Archives of Psychiatry: Official Journal of the Hong Kong College of Psychiatrists
https://www.readbyqxmd.com/read/27694083/the-relational-dimension-of-care-for-maternity-blues-and-its-relation-to-decompensation-of-a-psychiatric-disorder-during-the-intermediate-postpartum-period-in-cameroon
#10
C P Mboua, B A Nkoum, S P Abessouguié
In a setting such as Cameroon, where perinatal care offers few services for women with psychiatric problems during pregnancy, delivery, and the immediate postpartum period, the development of the relational dimension of care may help prevent severe psychiatric disorders . This study evaluates the role of the relational dimension of perinatal and early postpartum care (providing perinatal counseling and a space to speak) on women with blues on the intermediate-term outcomes of decompensation, in view of the importance of the emotional issues occurring in the perinatal period...
August 1, 2016: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/27693392/transgenerational-impairment-of-hippocampal-akt-mtor-signaling-and-behavioral-deficits-in-the-offspring-of-mice-that-experience-postpartum-depression-like-illness
#11
Ruyan Wu, Hailou Zhang, Wenda Xue, Zhilu Zou, Cai Lu, Baomei Xia, Wei Wang, Gang Chen
Postpartum depression (PPD) has adverse effects on offspring and increases their vulnerability to psychiatric disorders such as depression. Akt-mTOR signaling in the hippocampus is implicated in depression but its role in the behavioral deficits in PPD offspring remains unknown. By using a prepregnancy stress model of PPD in which Balb/c females that experience chronic stress before pregnancy show long-lasting PPD-like behaviors, we tested depression-like behaviors in PPD offspring (PPD-F1) at juvenile and adult ages as well as in the second generation (PPD-F2) produced by cross of male PPD-F1 with naïve females...
February 6, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/27640810/a-longitudinal-study-of-depression-and-gestational-diabetes-in-pregnancy-and-the-postpartum-period
#12
Stefanie N Hinkle, Germaine M Buck Louis, Shristi Rawal, Yeyi Zhu, Paul S Albert, Cuilin Zhang
AIMS/HYPOTHESIS: Depression and glucose intolerance commonly co-occur among non-pregnant individuals; however, the temporal relationship between gestational diabetes (GDM) and depression during pregnancy and the postpartum period is less understood. Our objective was to assess longitudinal associations between depression early in pregnancy and GDM risk, as well as GDM and subsequent risk of postpartum depression. METHODS: Data came from the prospective National Institute of Child Health and Human Development Fetal Growth Studies-Singleton cohort (2009-2013), and had been collected at 12 US clinical centres...
December 2016: Diabetologia
https://www.readbyqxmd.com/read/27618175/-facing-strangeness-perceptions-of-men-whose-partners-became-mentally-ill-after-delivering-a-baby
#13
Sabine Roebers, Oliver Razum, Katja Makowsky
Objective: This study explores men's perceptions of their partners' postpartum psychiatric disorders and their experiences of acute mental health care. Methods: Interviews were conducted with 13 men who had experienced postpartum psychiatric disorders of their partners. Data were analysed using grounded theory methodology. Results: Fathers were affected by their partners' postpartum psychiatric disorder and inpatient treatment. The core category found is the experience of strangeness. The men were faced with a changed partner, an unknown disorder and a confusing mental health care system...
September 12, 2016: Psychiatrische Praxis
https://www.readbyqxmd.com/read/27570512/suicide-during-perinatal-period-epidemiology-risk-factors-and-clinical-correlates
#14
REVIEW
Laura Orsolini, Alessandro Valchera, Roberta Vecchiotti, Carmine Tomasetti, Felice Iasevoli, Michele Fornaro, Domenico De Berardis, Giampaolo Perna, Maurizio Pompili, Cesario Bellantuono
Perinatal period may pose a great challenge for the clinical management and treatment of psychiatric disorders in women. In fact, several mental illnesses can arise during pregnancy and/or following childbirth. Suicide has been considered a relatively rare event during the perinatal period. However, in some mental disorders (i.e., postpartum depression, bipolar disorder, postpartum psychosis, etc.) have been reported a higher risk of suicidal ideation, suicide attempt, or suicide. Therefore, a complete screening of mothers' mental health should also take into account thoughts of suicide and thoughts about harming infants as well...
2016: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/27570341/psychiatric-morbidity-and-correlates-in-postpartum-women-in-a-tertiary-care-hospital
#15
Narendra Kumar, Anil Kumar Mysore Nagaraj, Umashree Koudike, Sumanth Mallikarjuna Majgi
BACKGROUND: A range of psychological disorders occur in women in the postpartum period apart from the traditional blues, postpartum depression and psychosis. These include obsession of infanticide, PTSD, morbid preoccupations regarding child birth and disorders of mother-infant relationships, though they are under emphasized. METHODS: it is a cross-sectional study conducted in the tertiary maternity care hospital. A total of 152 study subjects were interviewed on MINI (Mini International Neuropsychiatric Inventory) and GAF (Global Assessment of Functioning) within 2 weeks after delivery...
July 2016: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/27568278/mood-stabilizers-and-antipsychotics-during-breastfeeding-focus-on-bipolar-disorder
#16
REVIEW
Isabella Pacchiarotti, Jordi León-Caballero, Andrea Murru, Norma Verdolini, Maria Antonietta Furio, Corinna Pancheri, Marc Valentí, Ludovic Samalin, Eva Solé Roigé, Ana González-Pinto, Jose Manuel Montes, Antonio Benabarre, Jose Manuel Crespo, Consuelo de Dios Perrino, Jose Manuel Goikolea, Luis Gutiérrez-Rojas, André F Carvalho, Eduard Vieta
Breast milk is considered the best source of nutrients and provides much better protection than immune modified milk. However, the postpartum period is a phase of increased risk for all women to experience psychiatric symptoms and recurrences or new episodes of bipolar disorder (BD), especially in those who have discontinued treatment. This is a systematic review of the risks and benefits of mood stabilizers and antipsychotics during breastfeeding as they relate to the health and well-being of mothers and their infants...
October 2016: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27531210/-peripartum-management-plan-for-patients-with-mental-illnesses-strategies-to-reduce-the-risk-of-postpartum-relapse
#17
A Rohde, A Hocke, A Meurers, V Dorsch
BACKGROUND: Transition to parenthood is challenging but for women with a history of recurrent psychiatric disorders becoming a mother has a number of additional issues. Women with a history of mood disorders or psychoses are at increased risk for exacerbation in the vulnerable postpartum period and fear the potential risk of medication during pregnancy for the unborn child as much as they fear a relapse. In these difficult situations women and their families seek advice and support from mental health providers and obstetricians...
September 2016: Der Nervenarzt
https://www.readbyqxmd.com/read/27531206/-practical-implementation-of-an-integrated-care-model-in-mother-child-treatment
#18
J Kunze, K Wagner, E Fittig
This article summarizes the specific treatment options in the combined mother-child treatment for women with postpartum psychiatric disorders. The incidence of postpartum mental illness is high, especially for postpartum depression that probably occurs in10-15 % of cases. Mental disorders not only have a negative impact on the mental health of the women affected, such as chronification and suicidal tendencies but can also adversely affect the mother-child relationship as well as the emotional and cognitive development of the child...
September 2016: Der Nervenarzt
https://www.readbyqxmd.com/read/27511109/postpartum-psychiatric-emergency-visits-a-nested-case-control-study
#19
Lucy Church Barker, Paul Kurdyak, Kinwah Fung, Flora I Matheson, Simone Vigod
Mental health conditions are one of the most common reasons for postpartum emergency department (ED) visits. Characteristics of women using the ED and their mental health service use before presentation are unknown. We characterized all women in Ontario, Canada (2006-2012), who delivered a live born infant and had a psychiatric ED visit within 1 year postpartum (n = 8728). We compared those whose ED visit was the first physician mental health contact since delivery to those who had accessed mental health services on specific indicators of marginalization hypothesized to be associated with lower likelihood of mental health contact prior to the ED visit...
August 11, 2016: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/27421663/prediction-of-posttraumatic-stress-disorder-symptomatology-after-childbirth-a-croatian-longitudinal-study
#20
Azijada Srkalović Imširagić, Dražen Begić, Livija Šimičević, Žarko Bajić
BACKGROUND: Following childbirth, a vast number of women experience some degree of mood swings, while some experience symptoms of postpartum posttraumatic stress disorder. AIM: Using a biopsychosocial model, the primary aim of this study was to identify predictors of posttraumatic stress disorder and its symptomatology following childbirth. METHODS: This observational, longitudinal study included 372 postpartum women. In order to explore biopsychosocial predictors, participants completed several questionnaires 3-5 days after childbirth: the Impact of Events Scale Revised, the Big Five Inventory, The Edinburgh Postnatal Depression Scale, breastfeeding practice and social and demographic factors...
July 12, 2016: Women and Birth: Journal of the Australian College of Midwives
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