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Postpartum psychiatric disorders

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https://www.readbyqxmd.com/read/28152450/maternal-attachment-style-and-psychiatric-history-as-independent-predictors-of-mood-symptoms-in-the-immediate-postpartum-period
#1
Roberta Croce Nanni, Alfonso Troisi
BACKGROUND: There is evidence that both a past history of psychiatric illness and insecure attachment put women at risk for mood disturbances in the postpartum period. The aim of this study was to ascertain whether maternal insecure attachment is a risk factor for mood symptoms in the immediate postpartum period independently of the confounding effect of maternal psychiatric history. METHODS: A convenience sample of 120 mothers was assessed prenatally with the Maternal History of Mood Disturbances (MHMD), the Relationship Questionnaire (RQ), and in the first week after delivery with the Profile of Mood States (POMS)...
January 24, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28122520/postnatal-depression-screening-in-a-paediatric-primary-care-setting-in-italy
#2
Antonio Clavenna, Elena Seletti, Massimo Cartabia, Anna Didoni, Filomena Fortinguerra, Teresa Sciascia, Luca Brivio, Daniela Malnis, Maurizio Bonati
BACKGROUND: Postnatal depression is a non-psychotic depressive disorder that begins within 4 weeks of childbirth and occurs in 13% of mothers and 10% of fathers. A prospective study with the aim to evaluate the prevalence of postnatal depression by screening parents with the Edinburgh Postnatal Depression Scale (EPDS) in the Italian paediatric primary care setting was performed. METHODS: Mothers and fathers of infants born between 1 February and 31 July 2012, living in Italy's Milan-1 local health unit area, represented the target population of this pilot study...
January 25, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28114093/-cotard-s-syndrome-case-report-and-a-brief-review-of-literature
#3
N P Moschopoulos, S Kaprinis, J Nimatoudis
The term "Cotard's syndrome" is used to describe a number of clinical features, mostly hypochondriac and nihilistic delusions, the most characteristic of which are the ideas "I am dead" and "my internal organs do not exist". Besides, anxious and depressed mood, delusions of damnation, possession and immortality, suicidal and self-mutilating behavior are included. The first description of the syndrome was made in 1880 by Cotard, who presented the case of a female patient in a lecture. He originally named it "hypochondriac delusion", and some years later "delusion of negations", while it was named "Cotard delusion" after his death...
October 2016: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/28112056/obstetrical-pregnancy-and-socio-economic-predictors-for-new-onset-severe-postpartum-psychiatric-disorders-in-primiparous-women
#4
S Meltzer-Brody, M L Maegbaek, S E Medland, W C Miller, P Sullivan, T Munk-Olsen
BACKGROUND: Childbirth is a potent trigger for the onset of psychiatric illness in women including postpartum depression (PPD) and postpartum psychosis (PP). Medical complications occurring during pregnancy and/or childbirth have been linked to postpartum psychiatric illness and sociodemographic factors. We evaluated if pregnancy and obstetrical predictors have similar effects on different types of postpartum psychiatric disorders. METHOD: A population-based cohort study using Danish registers was conducted in 392 458 primiparous women with a singleton delivery between 1995 and 2012 and no previous psychiatric history...
January 23, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28077067/use-of-antidepressants-during-pregnancy-in-the-netherlands-observational-study-into-postpartum-interventions
#5
Noera Kieviet, Fokke de Jong, Fedde Scheele, Koert M Dolman, Adriaan Honig
BACKGROUND: Psychiatric disorders and use of selective antidepressants during pregnancy can have negative effects on mother and infant postpartum. This study aimed to provide evidence-based recommendations on observation of antidepressant-exposed mother-infant dyads. METHODS: In this observational study, mother-infant dyads were observed for possible consequences of either the maternal psychiatric disorder or fetal exposure to selective antidepressants during pregnancy...
January 11, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28032212/childhood-sexual-abuse-intimate-partner-violence-during-pregnancy-and-posttraumatic-stress-symptoms-following-childbirth-a-path-analysis
#6
Aline Gaudard E Silva de Oliveira, Michael Eduardo Reichenheim, Claudia Leite Moraes, Louise Michele Howard, Gustavo Lobato
The aim of the study was to explore the pathways by which childhood sexual abuse (CSA), psychological and physical intimate partner violence (IPV) during pregnancy, and other covariates relate to each other and to posttraumatic stress disorder (PTSD) symptoms in the postpartum period. The sample comprised 456 women who gave birth at a maternity service for high-risk pregnancies in Rio de Janeiro, Brazil, interviewed at 6-8 weeks after birth. A path analysis was carried out to explore the postulated pathways between exposures and outcome...
December 28, 2016: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28027955/oxytocin-pathways-in-the-intergenerational-transmission-of-maternal-early-life-stress
#7
REVIEW
Philipp Toepfer, Christine Heim, Sonja Entringer, Elisabeth Binder, Pathik Wadhwa, Claudia Buss
Severe stress in early life, such as childhood abuse and neglect, constitutes a major risk factor in the etiology of psychiatric disorders and somatic diseases. Importantly, these long-term effects may impact the next generation. The intergenerational transmission of maternal early life stress (ELS) may occur via pre-and postnatal pathways, such as alterations in maternal-fetal-placental stress physiology, maternal depression during pregnancy and postpartum, as well as impaired mother-offspring interactions...
February 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27927846/risk-of-postpartum-psychosis-after-ivf-treatment-a-nationwide-case-control-study
#8
Josefin Vikström, Ann Josefsson, Mats Hammar, Marie Bladh, Gunilla Sydsjö
STUDY QUESTION: Is the risk of postpartum psychosis (PPP) increased in women who give birth after IVF treatment compared to after spontaneous conception? SUMMARY ANSWER: The risk of PPP is not higher in the group of women who give birth after IVF treatment compared with women who give birth after spontaneous conception. WHAT IS KNOWN ALREADY: Women who conceive using IVF treatment can experience higher levels of pregnancy-specific distress and are at increased risk of pre-eclampsia, an immune-related condition which in turn has been linked to PPP, as well as other pregnancy and delivery complications, which also serve as PPP risk factors...
January 2017: Human Reproduction
https://www.readbyqxmd.com/read/27914245/perinatal-hypothalamic-pituitary-adrenal-axis-regulation-among-women-with-eating-disorders-and-their-infants
#9
A Easter, E Taborelli, A Bye, P A Zunszain, C M Pariante, J Treasure, U Schmidt, N Micali
BACKGROUND: Psychiatric illness is associated with heightened hypothalamic-pituitary-adrenal (HPA) axis activity during pregnancy which may have long term effects on infant stress regulation. HPA axis regulation has not previously been investigated in women with eating disorders (ED) or their infants during the perinatal period. METHODS: Women were recruited to a prospective longitudinal study in three groups: 1) current or active ED (C-ED=31), 2) past ED (P-ED=29) and healthy control (HC=57)...
February 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27829570/a-multi-state-analysis-of-postpartum-readmissions-in-the-united-states
#10
Mark A Clapp, Sarah E Little, Jie Zheng, Julian N Robinson
BACKGROUND: Readmission rates are used as a quality metric in medical and surgical specialties; however, little is known about obstetrics readmissions. OBJECTIVE: Our goals for this study were to describe the trends in postpartum readmissions over time; to characterize the common indications and associated diagnoses for readmissions; and to determine maternal, delivery, and hospital characteristics that may be associated with readmission. STUDY DESIGN: Postpartum readmissions occurring within the first 6 weeks after delivery in California, Florida, and New York were identified between 2004 and 2011 in State Inpatient Databases...
July 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27824771/maternal-deaths-from-suicide-and-overdose-in-colorado-2004-2012
#11
Torri D Metz, Polina Rovner, M Camille Hoffman, Amanda A Allshouse, Krista M Beckwith, Ingrid A Binswanger
OBJECTIVE: To ascertain demographic and clinical characteristics of maternal deaths from self-harm (accidental overdose or suicide) to identify opportunities for prevention. METHODS: We report a case series of pregnancy-associated deaths resulting from self-harm in the state of Colorado between 2004 and 2012. Self-harm deaths were identified from several sources, including death certificates. Birth and death certificates along with coroner, prenatal care, and delivery hospitalization records were abstracted...
December 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27810668/risk-factors-for-suicide-attempt-in-pregnancy-and-the-post-partum-period-in-women-with-serious-mental-illnesses
#12
Florence Gressier, Virginie Guillard, Odile Cazas, Bruno Falissard, Nine M-C Glangeaud-Freudenthal, Anne-Laure Sutter-Dallay
Suicide is a major public health concern worldwide, and mental disorders have been identified as a main risk factor. Suicide is also one of the leading causes of perinatal maternal mortality, but very few studies have focused on suicide attempts (SA) in the perinatal period. This work aims to assess risk factors associated with SA in pregnancy and in the post-partum period in women with mental health disorders. Women (n = 1439) with psychiatric disorders jointly admitted with their infant to 16 psychiatric Mother-Baby Units over 10 years (2001-2010) were assessed retrospectively for the occurrence of SA in pregnancy or the postpartum period...
October 13, 2016: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/27754485/perinatal-psychiatric-episodes-a-population-based-study-on-treatment-incidence-and-prevalence
#13
T Munk-Olsen, M L Maegbaek, B M Johannsen, X Liu, L M Howard, A di Florio, V Bergink, S Meltzer-Brody
Perinatal psychiatric episodes comprise various disorders and symptom severity, which are diagnosed and treated in multiple treatment settings. To date, no studies have quantified the incidence and prevalence of perinatal psychiatric episodes treated in primary and secondary care, which we aimed to do in the present study. We designed a descriptive prospective study and included information from Danish population registers to study first-time ever and recurrent psychiatric episodes during the perinatal period, including treatment at psychiatric facilities and general practitioners (GPs)...
October 18, 2016: Translational Psychiatry
https://www.readbyqxmd.com/read/27754482/predicting-early-psychiatric-readmission-with-natural-language-processing-of-narrative-discharge-summaries
#14
A Rumshisky, M Ghassemi, T Naumann, P Szolovits, V M Castro, T H McCoy, R H Perlis
The ability to predict psychiatric readmission would facilitate the development of interventions to reduce this risk, a major driver of psychiatric health-care costs. The symptoms or characteristics of illness course necessary to develop reliable predictors are not available in coded billing data, but may be present in narrative electronic health record (EHR) discharge summaries. We identified a cohort of individuals admitted to a psychiatric inpatient unit between 1994 and 2012 with a principal diagnosis of major depressive disorder, and extracted inpatient psychiatric discharge narrative notes...
October 18, 2016: Translational Psychiatry
https://www.readbyqxmd.com/read/27738382/maternal-and-fetal-outcomes-after-lamotrigine-use-in-pregnancy-a-retrospective-analysis-from-an-urban-maternal-mental-health-centre-in-new-zealand
#15
Chandni Prakash, Susan Hatters-Friedman, Charmian Moller-Olsen, Abigail North
INTRODUCTION: Pregnancy is a vulnerable period for recurrence of bipolar disorder. Discontinuation of mood stabilisers during pregnancy and the postpartum period can significantly increase the risk of recurrence of bipolar disorder. Lamotrigine is an anti-epileptic drug that has been approved for the maintenance treatment of bipolar disorder. Epilepsy literature has indicated that lamotrigine has a reassuring safety profile in pregnancy but there is little information on its effectiveness and safety in pregnant women with mental disorders...
August 15, 2016: Psychopharmacology Bulletin
https://www.readbyqxmd.com/read/27728876/a-pharmacological-mouse-model-suggests-a-novel-risk-pathway-for-postpartum-psychosis
#16
Trevor Humby, Ellen S Cross, Lauren Messer, Silvia Guerrero, William Davies
Postpartum psychosis (PP) is a severe psychiatric disorder affecting a small proportion of new mothers shortly after childbirth. The molecular pathophysiology underlying the disorder is currently poorly understood, and there are no amenable animal models for the condition; maternal deficiency for the enzyme steroid sulfatase has been proposed as a potential risk mechanism. Here we show that inhibition of steroid sulfatase with 667-COUMATE (10mg/kg p.o.) in new mouse mothers results in behavioural abnormalities that can be partially alleviated by the administration of the clinically-efficacious antipsychotic ziprasidone (0...
December 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27703098/cognitive-dysfunction-and-associated-behaviour-problems-in-postpartum-women-a-study-from-north-india
#17
P S Meena, R Soni, M Jain, C S Jilowa, Omprakash
OBJECTIVES: During and after childbirth women undergo tremendous psychological and biological changes. These biological changes, along with the stress of assuming the new role of mother, make postpartum women vulnerable to various psychiatric disorders including cognitive dysfunction, depression, and anxiety. Such problems are under-reported as they are difficult to identify, especially by caregivers who are more focused on the newborn. The present study aimed to evaluate the prevalence of behaviour problems and cognitive dysfunction during the postpartum period...
September 2016: East Asian Archives of Psychiatry: Official Journal of the Hong Kong College of Psychiatrists
https://www.readbyqxmd.com/read/27694083/the-relational-dimension-of-care-for-maternity-blues-and-its-relation-to-decompensation-of-a-psychiatric-disorder-during-the-intermediate-postpartum-period-in-cameroon
#18
C P Mboua, B A Nkoum, S P Abessouguié
In a setting such as Cameroon, where perinatal care offers few services for women with psychiatric problems during pregnancy, delivery, and the immediate postpartum period, the development of the relational dimension of care may help prevent severe psychiatric disorders . This study evaluates the role of the relational dimension of perinatal and early postpartum care (providing perinatal counseling and a space to speak) on women with blues on the intermediate-term outcomes of decompensation, in view of the importance of the emotional issues occurring in the perinatal period...
August 1, 2016: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/27693392/transgenerational-impairment-of-hippocampal-akt-mtor-signaling-and-behavioral-deficits-in-the-offspring-of-mice-that-experience-postpartum-depression-like-illness
#19
Ruyan Wu, Hailou Zhang, Wenda Xue, Zhilu Zou, Cai Lu, Baomei Xia, Wei Wang, Gang Chen
Postpartum depression (PPD) has adverse effects on offspring and increases their vulnerability to psychiatric disorders such as depression. Akt-mTOR signaling in the hippocampus is implicated in depression but its role in the behavioral deficits in PPD offspring remains unknown. By using a prepregnancy stress model of PPD in which Balb/c females that experience chronic stress before pregnancy show long-lasting PPD-like behaviors, we tested depression-like behaviors in PPD offspring (PPD-F1) at juvenile and adult ages as well as in the second generation (PPD-F2) produced by cross of male PPD-F1 with naïve females...
February 6, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/27640810/a-longitudinal-study-of-depression-and-gestational-diabetes-in-pregnancy-and-the-postpartum-period
#20
Stefanie N Hinkle, Germaine M Buck Louis, Shristi Rawal, Yeyi Zhu, Paul S Albert, Cuilin Zhang
AIMS/HYPOTHESIS: Depression and glucose intolerance commonly co-occur among non-pregnant individuals; however, the temporal relationship between gestational diabetes (GDM) and depression during pregnancy and the postpartum period is less understood. Our objective was to assess longitudinal associations between depression early in pregnancy and GDM risk, as well as GDM and subsequent risk of postpartum depression. METHODS: Data came from the prospective National Institute of Child Health and Human Development Fetal Growth Studies-Singleton cohort (2009-2013), and had been collected at 12 US clinical centres...
December 2016: Diabetologia
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