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https://www.readbyqxmd.com/read/27864816/giant-insulinoma-report-of-a-case-and-review-of-published-reports
#1
Kazumitsu Ueda, Tetsuro Taira, Hiroyuki Hakoda, Shoko Nakata, Shinya Okata, Takeshi Nagai, Shigeo Aoki, Hideyuki Mishima, Akihiko Sako, Tsunehiko Maruyama, Minoru Okumura
BACKGROUND: Larger insulinomas are reportedly more likely to be malignant; however, their biological behavior has not been clearly elucidated. We here report the characteristics and treatment of a giant insulinoma with local invasion and lymph node metastasis. We also review published reports concerning the clinical features of giant insulinomas and comparing their grading with that of pancreatic neuroendocrine tumors. CASE PRESENTATION: A 71-year-old man was referred to our hospital for investigation of persistent hypoglycemia...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27853168/depressive-symptoms-and-prevalence-of-erectile-dysfunction-in-japanese-patients-with-type-2-diabetes-mellitus-the-dogo-study
#2
S Furukawa, T Sakai, T Niiya, H Miyaoka, T Miyake, S Yamamoto, K Maruyama, T Ueda, H Senba, M Torisu, H Minami, M Onji, T Tanigawa, B Matsuura, Y Hiasa, Y Miyake
In several studies of patients with type 2 diabetes mellitus, a positive association between depressive symptoms and erectile dysfunction (ED) has been reported. No evidence exists, however, regarding the association between depressive symptoms and ED among Japanese patients with type 2 diabetes mellitus. Thus, we examined this issue among Japanese patients with type 2 diabetes mellitus. Study subjects were 469 male Japanese patients with type 2 diabetes mellitus, aged 19 years or over. ED, moderate to severe ED and severe ED were defined as present when a subject had a Sexual Health Inventory for Men score <22, <12 and <8, respectively...
November 17, 2016: International Journal of Impotence Research
https://www.readbyqxmd.com/read/27836682/self-reported-sitting-time-and-prevalence-of-erectile-dysfunction-in-japanese-patients-with-type-2-diabetes-mellitus-the-dogo-study
#3
Shinya Furukawa, Takenori Sakai, Tetsuji Niiya, Hiroaki Miyaoka, Teruki Miyake, Shin Yamamoto, Sayaka Kanzaki, Koutatsu Maruyama, Keiko Tanaka, Teruhisa Ueda, Hidenori Senba, Masamoto Torisu, Hisaka Minami, Takeshi Tanigawa, Bunzo Matsuura, Yoichi Hiasa, Yoshihiro Miyake
AIMS: No evidence exists regarding the association between sitting time and erectile dysfunction (ED) among patients with type 2 diabetes mellitus. The aim of this study was to evaluate the association between self-reported sitting time and ED among patients with type 2 diabetes mellitus. METHODS: Study subjects were 430 male Japanese patients with type 2 diabetes mellitus (mean age, 60.5years). A self-administered questionnaire was used to collect information on the variables under study...
October 18, 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27799713/deviation-in-the-recovery-of-the-lower-limb-and-respiratory-muscles-of-patients-with-polymyositis-a-preliminary-clinical-study
#4
Yuichi Nishikawa, Naohisa Hosomi, Hiroki Ueno, Takashi Kurashige, Kazuhide Ochi, Tetsuya Takahashi, Naoya Orita, Kazuyuki Ueda, Hirofumi Maruyama, Hiroaki Kimura, Masayasu Matsumoto
[Purpose] The purposes of this study were to quantify the serial changes in lower limb and respiratory muscle strengths and to evaluate the acute effects of physiotherapy in polymyositis patients. [Subjects and Methods] Five patients (57.6 ± 9.0 years, 50 to 72; four females) received physiotherapy five days a week for four weeks. The lower limb and respiratory muscle strength, the % vital capacity, and the Barthel index were evaluated at baseline and after the intervention. [Results] The patient's symptoms and creatine kinase values did not change, and after four weeks, all of the patients exhibited significantly increased outcomes compared with the baseline...
September 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/27788774/alcohol-consumption-and-prevalence-of-erectile-dysfunction-in-japanese-patients-with-type-2-diabetes-mellitus-baseline-data-from-the-dogo-study
#5
Shinya Furukawa, Takenori Sakai, Tetsuji Niiya, Hiroaki Miyaoka, Teruki Miyake, Shin Yamamoto, Koutatsu Maruyama, Teruhisa Ueda, Keiko Tanaka, Hidenori Senba, Yasuhiko Todo, Masamoto Torisu, Hisaka Minami, Morikazu Onji, Takeshi Tanigawa, Bunzo Matsuura, Yoichi Hiasa, Yoshihiro Miyake
Diabetes mellitus and heavy alcohol consumption are both associated with vascular disease, a category that includes erectile dysfunction (ED). However, the association between alcohol consumption and ED among patients with type 2 diabetes mellitus remains unclear. The aim of the present multicenter cross-sectional study was to investigate the relationship between drinking frequency, weekly alcohol consumption, daily alcohol consumption, and ED among Japanese patients with type 2 diabetes mellitus. Study subjects were 340 male Japanese patients with type 2 diabetes mellitus, aged 19-70 years, who had undergone blood tests at our institutions...
September 2016: Alcohol
https://www.readbyqxmd.com/read/27774267/the-clinical-significance-of-plasma-neopterin-in-heart-failure-with-preserved-left-ventricular-ejection-fraction
#6
Eiichiro Yamamoto, Yoshihiro Hirata, Takanori Tokitsu, Hiroaki Kusaka, Noriaki Tabata, Kenichi Tsujita, Megumi Yamamuro, Koichi Kaikita, Hiroshi Watanabe, Seiji Hokimoto, Toru Maruyama, Hisao Ogawa
AIMS: Although inflammation plays an important role in the pathogenesis of heart failure (HF), the precise pathophysiological role of inflammation in HF with preserved left ventricular ejection fraction (HFpEF) still remains unclear. Hence, we examined the clinical significance of plasma neopterin, an inflammatory biomarker, in HFpEF patients. METHODS AND RESULTS: In the present study, we recruited consecutive HFpEF patients hospitalized in Kumamoto University Hospital, and further measured plasma neopterin by high-performance liquid chromatography and serum derivatives of reactive oxidative metabolites (DROM), a new biomarker of reactive oxygen species...
March 2016: ESC Heart Failure
https://www.readbyqxmd.com/read/27773909/blunted-autonomic-responses-and-low-grade-inflammation-in-mongolian-adults-born-at-low-birth-weight
#7
Sarina Bao, Emi Kanno, Ryoko Maruyama
Low birth weight (LBW) has been considered as a risk factor for adult hypertension that is associated with deterioration of autonomic functions and low-grade inflammation. To explore the above effects of LBW, we measured blood pressure (BP) and heart rate variability during postural change from a supine position to a sitting position in 21 healthy Mongolian adults aged 23-34 years: 4 with LBW (birth weight < 2,500 g), 13 with normal birth weight (NBW, 2,500 g ≤ birth weight < 4,000 g), and 4 with high birth weight (HBW, ≥ 4,000 g)...
2016: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/27716961/left-ventricular-stiffness-estimated-by-diastolic-wall-strain-is-associated-with-paroxysmal-atrial-fibrillation-in-structurally-normal-hearts
#8
Shunsuke Uetake, Mitsunori Maruyama, Teppei Yamamoto, Katsuhito Kato, Yasushi Miyauchi, Yoshihiko Seino, Wataru Shimizu
BACKGROUND: Left ventricular (LV) diastolic dysfunction depends on an impaired relaxation and stiffness. Abnormal LV relaxation contributes to the development of atrial fibrillation (AF), but the role of LV stiffness in AF remains unclear. HYPOTHESIS: Diastolic wall strain (DWS), a load-independent, noninvasive direct measure of LV stiffness, correlates with prevalent AF. METHODS: This study included 328 consecutive subjects with structurally normal hearts: 164 paroxysmal AF patients and 164 age- and sex-matched (1:1) controls...
October 7, 2016: Clinical Cardiology
https://www.readbyqxmd.com/read/27699494/survival-and-clinical-results-of-a-modified-crosse-de-hockey-procedure-for-chronic-isolated-patellofemoral-joint-osteoarthritis-mid-term-follow-up
#9
Hiroaki Kanazawa, Yuichiro Maruyama, Katsuo Shitoto, Minoru Yokoyama, Kazuo Kaneko
BACKGROUND: The optimum treatment for isolated patellofemoral joint osteoarthritis (PFJ-OA) remains controversial. The aim of this study was to assess the mid-term clinical results of a modified crosse de hockey procedure for the treatment of isolated PFJ-OA. MATERIALS AND METHODS: We assessed 37 knees in 31 patients treated by a modified crosse de hockey procedure. The mean age was 57.6 years (range, 46-75 years) and mean follow-up was 90.1 months (range, 24-216 months)...
October 3, 2016: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/27623814/comparison-of-plasma-amino-acid-profile-based-index-and-ca125-in-the-diagnosis-of-epithelial-ovarian-cancers-and-borderline-malignant-tumors
#10
Etsuko Miyagi, Yasuyo Maruyama, Tae Mogami, Reiko Numazaki, Atsuko Ikeda, Hiroshi Yamamoto, Fumiki Hirahara
BACKGROUND: We previously developed a new plasma amino acid profile-based index (API) to detect ovarian, cervical, and endometrial cancers. Here, we compared API to serum cancer antigen 125 (CA125) for distinguishing epithelial ovarian malignant tumors from benign growths. METHODS: API and CA125 were measured preoperatively in patients with ovarian tumors, which were later classified into 59 epithelial ovarian cancers, 21 epithelial borderline malignant tumors, and 97 benign tumors including 40 endometriotic cysts...
September 13, 2016: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27615262/elevated-hba1c-levels-are-associated-with-the-blunted-autonomic-response-assessed-by-heart-rate-variability-during-blood-volume-reduction
#11
Miho Kamakura, Ryoko Maruyama
A high glycemic status increases the risk for autonomic dysfunction and cardiovascular failure. The aim of this study was to investigate time-dependent changes in the autonomic response and cardiovascular dynamics and the association between the level of hemoglobin A1c (HbA1c) and autonomic response during blood volume reduction. The study population consisted of 26 preoperative participants who were scheduled for autologous blood donation (200-400 mL of whole blood) for intraoperative or postoperative use...
2016: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/27564779/smoking-and-prevalence-of-nocturia-in-japanese-patients-with-type-2-diabetes-mellitus-a-post-hoc-analysis-of-the-dogo-study
#12
Shinya Furukawa, Takenori Sakai, Tetsuji Niiya, Hiroaki Miyaoka, Teruki Miyake, Shin Yamamoto, Sayaka Kanzaki, Koutatsu Maruyama, Keiko Tanaka, Teruhisa Ueda, Hidenori Senba, Masamoto Torisu, Hisaka Minami, Morikazu Onji, Takeshi Tanigawa, Bunzo Matsuura, Yoichi Hiasa, Yoshihiro Miyake
AIMS: No evidence exists regarding the association between smoking status and nocturia among patients with type 2 diabetes mellitus. We evaluated this association among Japanese patients with type 2 diabetes mellitus by post-hoc analysis. METHODS: Study subjects were 817 Japanese patients with type 2 diabetes mellitus. Study subjects were considered to have nocturia if they answered "once or more" to the question: "Within one week, how many times do you typically wake up to urinate from sleeping at night until waking in the morning?" We used the following three outcomes: (1) nocturia was ≥1 voids per night; (2) moderate nocturia was ≥2 voids per night; and (3) severe nocturia was ≥3 voids per night...
August 26, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27553628/neutrophil-lymphocyte-ratio-and-platelet-lymphocyte-ratio-as-predictors-of-wound-healing-failure-in-head-and-neck-reconstruction
#13
Yoko Maruyama, Keita Inoue, Keita Mori, Katsuya Gorai, Ryo Shimamoto, Tetsuro Onitsuka, Hiroyoshi Iguchi, Mutsumi Okazaki, Masahiro Nakagawa
CONCLUSIONS: In microsurgical head and neck reconstruction, a higher rate of post-operative wound complication could be predicted by a lower pre-operative neutrophil ratio (< 64.9%), neutrophil-lymphocyte ratio (NLR) (< 3.5), and platelet-lymphocyte ratio (PLR) (< 160). OBJECTIVES: To evaluate the predictor of post-operative wound complications in microsurgical head and neck reconstruction. METHODS: Patients who were undergoing tumor ablation and microsurgical reconstruction from April 2011 to March 2014 were analyzed retrospectively...
August 24, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27522583/prognostic-significance-of-hla-class-i-and-ii-expression-in-patients-with-diffuse-large-b-cell-lymphoma-treated-with-standard-chemoimmunotherapy
#14
Kohei Tada, Akiko Miyagi Maeshima, Nobuyoshi Hiraoka, Nobuhiko Yamauchi, Dai Maruyama, Sung-Won Kim, Takashi Watanabe, Naoyuki Katayama, Yuji Heike, Kensei Tobinai, Yukio Kobayashi
Loss of tumor cell human leukocyte antigen (HLA) is an immune escape mechanism for malignancies. However, the effect of low HLA class I or class II expression in diffuse large B cell lymphoma (DLBCL) treated with chemoimmunotherapy with the monoclonal antibody rituximab is largely unknown. We retrospectively analyzed samples and other data from 144 patients with DLBCL who were newly diagnosed in our institution and treated with standard R-CHOP therapy. We used antibodies against pan-HLA class I and pan-HLA class II molecules to assess HLA expression and its effect on prognosis...
October 2016: Cancer Immunology, Immunotherapy: CII
https://www.readbyqxmd.com/read/27502315/usefulness-of-peripheral-arterial-signs-in-the-evaluation-of-aortic-regurgitation
#15
Hirokazu Shiraishi, Takeshi Shirayama, Naoki Maruyama, Satoshi Kaimoto, Asako Otakara, Ritsuko Kurimoto, Naohiko Nakanishi, Takeshi Nakamura, Tetsuhiro Yamano, Akiyoshi Matsumuro, Kiyoshi Doi, Hitoshi Yaku, Satoaki Matoba
BACKGROUND: Early diagnosis and optimal timing of surgical repair for chronic aortic regurgitation (AR) are topics of interest, because left ventricular compensation delays the clinical signs of the early stages of left ventricular dysfunction. Various physical signs have been described as indicators of chronic AR, but AR screening can be difficult depending on the proficiency of primary care providers. The recent use of the cardio-ankle vascular index (CAVI) measurement to assess peripheral atherosclerosis may detect AR objectively and simply because its arterial pulse wave configuration is closely related to the physical signs of AR...
August 5, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/27477404/functional-outcomes-of-decompressive-craniectomy-in-patients-with-malignant-middle-cerebral-artery-infarction-and-their-association-with-preoperative-thalamus-deformation-an-analysis-of-12-patients
#16
Takuya Fukuoka, Takeshi Hayashi, Masayuki Ohira, Yuji Kato, Ichiro Deguchi, Hajime Maruyama, Tetsuya Abe, Hiroyasu Sano, Satoko Mizuno, Yuito Nagamine, Hiroki Kurita, Masaki Takao, Norio Tanahashi
Objective Decompressive craniectomy (DC) in patients with malignant middle cerebral artery (MCA) infarction is known to decrease the mortality rate. However, the functional outcomes (communication and oral intake) of this procedure remain unclear. Most patients with malignant MCA infarction exhibit a loss of consciousness, which may be principally governed by the thalamus. We herein investigated the functional outcomes of DC at 90 days after the onset of malignant MCA infarction and their association with preoperative thalamus deformation, which can occur due to pressure and edema...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27367239/letter-to-the-editor-the-bispectral-index-is-a-dimensionless-number
#17
Kotoe Kamata, Satoshi Hagihira, Takashi Maruyama, Yoshihiro Muragaki, Makoto Ozaki
No abstract text is available yet for this article.
July 1, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27245511/effect-of-dietary-energy-and-polymorphisms-in-brap-and-ghrl-on-obesity-and-metabolic-traits
#18
Takahiro Imaizumi, Masahiko Ando, Masahiro Nakatochi, Yoshinari Yasuda, Hiroyuki Honda, Yachiyo Kuwatsuka, Sawako Kato, Takaaki Kondo, Masamitsu Iwata, Toru Nakashima, Hiroshi Yasui, Hideki Takamatsu, Hiroshi Okajima, Yasuko Yoshida, Shoichi Maruyama
OBJECTIVE: Obesity, a risk factor for all-cause and cardiovascular mortality, is a major health concerns among middle-aged men. The aim of this study was to investigate a possible association of dietary habits and obesity related single nucleotide polymorphisms (SNPs) with obesity and metabolic abnormalities. METHODS: We conducted a retrospective cohort study using annual health examination data of 5112 male workers, obtained between 2007 and 2011. Average dietary energy was estimated using electronically collected meal purchase data from cafeteria...
May 27, 2016: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/27242373/urinary-soluble-cd163-level-reflects-glomerular-inflammation-in-human-lupus-nephritis
#19
Nobuhide Endo, Naotake Tsuboi, Kazuhiro Furuhashi, Yiqin Shi, Qiuna Du, Tomoko Abe, Mayuko Hori, Takahiro Imaizumi, Hangsoo Kim, Takayuki Katsuno, Takenori Ozaki, Tomoki Kosugi, Seiichi Matsuo, Shoichi Maruyama
BACKGROUND: In addition to classically activated macrophages that have effector roles in tissue injury, alternatively activated M2 macrophages are involved in the resolution of inflammation in animal models of kidney disease. To clarify the clinical relevance of macrophage phenotypes in human glomerular diseases, we evaluated the renal accumulation of macrophages and plasma and urine levels of CD163, an M2 marker, in lupus nephritis (LN) patients. METHODS: Kidney biopsies and plasma and urine samples were obtained from LN patients who underwent renal biopsy between 2008 and 2012...
May 30, 2016: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27180646/nocturia-and-prevalence-of-erectile-dysfunction-in-japanese-patients-with-type-2-diabetes-mellitus-the-dogo-study
#20
Shinya Furukawa, Takenori Sakai, Tetsuji Niiya, Hiroaki Miyaoka, Teruki Miyake, Shin Yamamoto, Koutatsu Maruyama, Keiko Tanaka, Teruhisa Ueda, Hidenori Senba, Masamoto Torisu, Hisaka Minami, Morikazu Onji, Takeshi Tanigawa, Bunzo Matsuura, Yoichi Hiasa, Yoshihiro Miyake
AIMS/INTRODUCTION: Several epidemiological studies have reported a positive association between nocturia and erectile dysfunction (ED). Yet only limited evidence exists regarding the association between nocturia and ED among patients with type 2 diabetes mellitus, although nocturia and ED are common among type 2 diabetes mellitus patients. MATERIAL AND METHODS: Study participants were 332 male Japanese patients with type 2 diabetes mellitus, aged 19-70 years, who had undergone blood tests at our institutions...
September 2016: Journal of Diabetes Investigation
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