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https://www.readbyqxmd.com/read/28645095/tooth-coronal-index-and-pulp-tooth-ratio-in-dental-age-estimation-on-digital-panoramic-radiographs-a-comparative-study
#1
Supreet Jain, Ravleen Nagi, Minal Daga, Ashutosh Shandilya, Aastha Shukla, Abhinav Parakh, Afshan Laheji, Rahul Singh
BACKGROUND: Assessment of an age of an individual whether living or dead through teeth is one of the most reliable and simple method to calculate age than skeletal remains especially when they are in poor conditions. OBJECTIVES: The study was carried out with aim of (i) to evaluate reliability of dental age assessment through two different methods for adults i.e. tooth coronal index and pulp/tooth ratio using digital panoramic radiographs and (ii) to compare these methods for their accuracy in age determination...
May 12, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28643909/the-fate-of-osterix-expressing-mesenchymal-cells-in-dental-root-formation-and-maintenance
#2
A Takahashi, N Ono, W Ono
OBJECTIVES: Osterix (Osx)-expressing mesenchymal cells are progenitors for tooth root forming cells. The aim of this study was to reveal the fates of Osx-expressing cells during and after root formation using a lineage tracing experiment. MATERIAL AND METHODS: To reveal the fates of Osx-expressing dental mesenchymal progenitors, we took advantage of tamoxifen-inducible Cre reporter system. Osx-creER; R26R-tdTomato mice received tamoxifen (0.1 mg/body) at postnatal day 3 (P3)...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28638345/heterogeneity-and-developmental-connections-between-cell-types-inhabiting-teeth
#3
REVIEW
Jan Krivanek, Igor Adameyko, Kaj Fried
Every tissue is composed of multiple cell types that are developmentally, evolutionary and functionally integrated into the unit we call an organ. Teeth, our organs for biting and mastication, are complex and made of many different cell types connected or disconnected in terms of their ontogeny. In general, epithelial and mesenchymal compartments represent the major framework of tooth formation. Thus, they give rise to the two most important matrix-producing populations: ameloblasts generating enamel and odontoblasts producing dentin...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28636235/stem-cell-based-tooth-and-periodontal-regeneration
#4
Lei Hu, Yi Liu, Songlin Wang
Currently regeneration of tooth and periodontal damage still remains great challenge. Stem cell-based tissue engineering raised novel therapeutic strategies for tooth and periodontal repair. Stem cells for tooth and periodontal regeneration include dental pulp stem cells (DPSCs), periodontal ligament stem cells (PDLSCs), stem cells from the dental apical papilla (SCAPs), and stem cells from human exfoliated deciduous teeth (SHEDs), dental follicle stem cells (DFSCs), dental epithelial stem cells (DESCs), bone marrow mesenchymal stem cells (BMMSCs), adipose-derived stem cells (ADSCs), embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs)...
June 21, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28624073/predicting-extension-of-cracks-to-the-root-from-the-dimensions-in-the-crown-a-preliminary-in%C3%A2-vitro-study
#5
Min Chen, Kaiyu Fu, Feng Qiao, Xu Zhang, Yi Fan, Lijun Wang, Peng Li, Zhou Wu, Ligeng Wu
BACKGROUND: In this study, the authors investigated whether extension of a tooth crack into the root can be predicted by the appearance of the crack in the crown in vitro. METHODS: The authors obtained 22 cracked teeth from 22 patients who underwent extraction, and they scanned the teeth using microcomputed tomography. The length and width of the crack on the occlusal surface (LOS and WOS, respectively) and the length of the crack on the proximal surface (LCPS) were measured on 3-dimensional reconstruction images...
June 14, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28616151/therapeutic-potential-of-dental-stem-cells
#6
REVIEW
Elna Paul Chalisserry, Seung Yun Nam, Sang Hyug Park, Sukumaran Anil
Stem cell biology has become an important field in regenerative medicine and tissue engineering therapy since the discovery and characterization of mesenchymal stem cells. Stem cell populations have also been isolated from human dental tissues, including dental pulp stem cells, stem cells from human exfoliated deciduous teeth, stem cells from apical papilla, dental follicle progenitor cells, and periodontal ligament stem cells. Dental stem cells are relatively easily obtainable and exhibit high plasticity and multipotential capabilities...
January 2017: Journal of Tissue Engineering
https://www.readbyqxmd.com/read/28613059/-experimental-study-of-transforming-growth-factor-%C3%AE-3-combined-with-dental-pulp-stem-cells-in-promoting-the-implant-s-osseointegration
#7
T Wang, Huojia Muhetaer, J Li
Objective: To investigate the effect of transforming growth factor-β3 (TGF-β3) and dental pulp stem cells (DPSC) in promoting the implant's osteointegration. Methods: Thirty-three New Zealand white rabbits were randomly divided into phosphate buffer saline (PBS) group, DPSC group and TGF-β3 + DPSC group (12 rabbits/group). Two teeth from the rabbits's mandibular incisors or molars were pulled out randomly, then implant were placed in the tooth extraction site immediately. In PBS group, the implant area was filled with Bio-Oss powder 0...
June 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28612428/outcomes-and-prognostic-factors-that-influence-the-success-of-tooth-autotransplantation-in-children-and-adolescents
#8
Vasiliki Kafourou, Huei Jinn Tong, Peter Day, Nadine Houghton, R James Spencer, Monty Duggal
BACKGROUND/AIM: Tooth autotransplantation has been advocated for replacement of missing teeth, or teeth that are unsuitable for restoration. The aim of this study was to investigate the outcomes and prognostic factors that influenced the success of tooth transplantation in a paediatric population. MATERIALS AND METHODS: Data was extracted from the records of 75 patients (89 teeth). Demographic and prognostic factors were recorded and analyzed for the clinical and radiographic outcomes for periodontal ligament (PDL) and pulp healing of transplanted teeth...
June 14, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28611689/monitoring-notch-signaling-associated-activation-of-stem-cell-niches-within-injured-dental-pulp
#9
Thimios A Mitsiadis, Javier Catón, Pierfrancesco Pagella, Giovanna Orsini, Lucia Jimenez-Rojo
Dental pulp stem/progenitor cells guarantee tooth homeostasis, repair and regeneration throughout life. The decision between renewal and differentiation of these cells is influenced by physical and molecular interactions with stromal cells and extracellular matrix molecules forming the specialized microenvironment of dental pulp stem cell niches. Here we study the activation of putative pulp niches after tooth injury through the upregulation of Notch signaling pathway. Notch1, Notch2, and Notch3 molecules were used as markers of dental pulp stem/progenitor cells...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28602850/repair-may-increase-survival-of-direct-posterior-restorations-a-practice-based-study
#10
Luciano Casagrande, Mark Laske, Ewald M Bronkhorst, Marie Charlotte D N J M Huysmans, Niek J M Opdam
OBJECTIVES: To investigate repairs of direct restorations by a group of Dutch general dental practitioners (GDPs) and its consequences on longevity of restorations. METHODS: Data set was based on dental records of patients attending 11 general dental practices (24 Dentists) in the Netherlands. Patients that received Class II Amalgam or Composite restorations were included in the study. The outcomes were considered in two levels: "Success" - When no intervention was necessary on the original restoration, it was considered clinically acceptable...
June 8, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28595095/differential-expression-between-dsp-only-and-dsp-pp523-transcripts-in-rat-molar-teeth
#11
Ya-Qin Zhu, Ryan M Song, Helena H Ritchie
OBJECTIVE: To compare the expression patterns of two multiple transcripts derived from DSP-PP gene during tooth development. One is DSP-only transcript (i.e. does not encode PP) and the other is DSP-PP523 transcript, a main DSP-PP transcript. DESIGN: Unique antisense and sense riboprobes were generated from DSP-only and DSPPP523 cDNAs for in situ studies to examine DSP-only and DSP-PP523 transcript expression in developing molars. Paraffin-embedded sections (5-7μ m) from embryonic 20day, postnatal 2, 3 and 6days were deparaffined and hydrated...
May 31, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28590837/regulation-and-measurement-of-the-heat-generated-by-automatic-tooth-preparation-in-a-confined-space
#12
Fusong Yuan, Jianqiao Zheng, Yuchun Sun, Yong Wang, Peijun Lyu
OBJECTIVE: The aim of this study was to assess and regulate heat generation in the dental pulp cavity and circumambient temperature around a tooth during laser ablation with a femtosecond laser in a confined space. BACKGROUND DATA: The automatic tooth preparing technique is one of the traditional oral clinical technology innovations. In this technique, a robot controlled an ultrashort pulse laser to automatically complete the three-dimensional teeth preparing in a confined space...
June 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28584468/determination-of-age-sex-and-blood-group-from-a-single-tooth
#13
Amit K Nayar, Swati Parhar, Gagandeep Thind, Aman Sharma, Divya Sharma
BACKGROUND: Human identification is one of the most challenging subjects that human has been confronted with. Through the ages, odontological examinations have been a critical determinant in the search of human identity. Data in the form of age, gender, and blood group might provide vital clues in such investigations. In the recent times, it has been often desirable to preserve tissues for further investigations following the unfolding of certain events or discovery of new data. Hence, it is important to gather as much data as possible using less tissue...
January 2017: Journal of Forensic Dental Sciences
https://www.readbyqxmd.com/read/28584467/the-credibility-of-dental-pulp-in-human-blood-group-identification
#14
Vrinda Saxena, Manish Jain, Vidhatri Tiwari, Binu Santha, Anshika Khare, Ravikant Shah
BACKGROUND: The identification of unknown individual has always been of paramount importance to the society. Blood groups are excellent aids to these pursuits. Dental tissue acts beneficial because tooth is the hardest of all human tissues, and they can be preserved intact for a long period of time after the death of the individual. Hence, this study is conducted to evaluate the role of dental pulp in identification of human blood group. AIM: To determine the ABO blood grouping from the pulpal tissue of an extracted tooth and to correlate the same with blood group details obtained from the study subjects...
January 2017: Journal of Forensic Dental Sciences
https://www.readbyqxmd.com/read/28583237/intrapulpal-temperature-rise-during-light-activation-of-restorative-composites-in-a-primary-molar
#15
Craig V Vinall, Tales C Garcia-Silva, Jennifer S B Lou, Martha H Wells, Daranee Tantbirojn, Antheunis Versluis
PURPOSE: To investigate intrapulpal temperature rise in a primary molar during light activation of a composite restoration to determine if clinically significant pulpal temperatures (greater than 5.5 degrees Celsius) were reached. METHODS: Restorative composites (EsthetX HD, Filtek Supreme Ultra, Filtek Bulk Fill) were placed into a primary molar with occlusal preparation (1.5 mm depth; remaining pulpal floor thickness one mm). The pulp was extirpated through a root access to place a thermocouple against the pulpal roof...
May 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/28571484/sclerostin-deficiency-promotes-reparative-dentinogenesis
#16
A-M Collignon, N Amri, J Lesieur, J Sadoine, S Ribes, S Menashi, S Simon, A Berdal, G Y Rochefort, C Chaussain, C Gaucher
In humans, the SOST gene encodes sclerostin, an inhibitor of bone growth and remodeling, which also negatively regulates the bone repair process. Sclerostin has also been implicated in tooth formation, but its potential role in pulp healing remains unknown. The aim of this study was to explore the role of sclerostin in reparative dentinogenesis using Sost knockout mice ( Sost(-/-)). The pulps of the first maxillary molars were mechanically exposed in 3-mo-old Sost(-/-) and wild-type (WT) mice ( n = 14 mice per group), capped with mineral trioxide aggregate cement, and the cavities were filled with a bonded composite resin...
March 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28571287/surgical-management-of-a-rare-case-of-massive-compound-odontome-associated-with-missing-primary-tooth
#17
Elengkumaran Sankaran, Sangeetha Narasimhan, K S Sabitha, Punit Chitlangia
Odontomes are considered to be the most common odontogenic tumours of the jaws. They are benign, mixed tumours arising from the remnants of both odontogenic epithelium and the ectomesenchyme resulting in the deposition of varied propotions of enamel, dentin, cementum and pulp tissues. As these lesions show deficiency only in structural arrangement, some authors consider odontomes as hamartomas or tumour like malformations. Though these lesions are more common in children, very few cases have been reported in less than five years age group...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28555199/multidisciplinary-approach-for-replacement-%C3%A2-root-resorption-following-severe-intrusive-luxation-%C3%A2-a-case-report-of-decoronation
#18
Thiago Farias Rocha Lima, Julio Vargas Neto, Renato Corrêa Vianna Casarin, Maíra Prado, Brenda Paula Figueiredo de Gomes, José Flávio Affonso de Almeida, Alexandre Augusto Zaia, Adriana de Jesus Soares
Intrusive luxation is a severe trauma-related event with a high frequency of pulp necrosis and root resorption. A common complication following intrusion is tooth ankylosis, which can extend to progressive replacement root resorption. An increasing infraposition in growing individuals can also occur. Decoronation is a new conservative treatment for cases of tooth ankylosis in young patients who have not finished growing. In this surgical technique, the tooth crown is removed and the root with replacement resorption process remains inside the alveolus...
2017: Quintessence International
https://www.readbyqxmd.com/read/28554314/epigenetics-in-odontogenesis-and-its-influences
#19
Chuwen Li, Yujia Cui, Changchun Zhou, Jianxun Sun, Xuedong Zhou
Odontogenesis, including amelogenesis, dentin and pulp development and root formation, is fundamentally controlled by the genome. However, epigenetic factors have indispensable effects during odontogenesis. The regulation of cell differentiation, proliferation and apoptosis by epigenetic factors is fundamental in odontogenesis, with its appropriate procedure being vital in normal tooth development. Previous studies have shown that exogenous factors, such as the environment, that cause hypomethylation and hypermethylation in DNA may lead to dental differences in monozygotic twin pairs...
May 29, 2017: Current Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28545523/l-mimosine-and-hypoxia-can-increase-angiogenin-production-in-dental-pulp-derived-cells
#20
Klara Janjić, Michael Edelmayer, Andreas Moritz, Hermann Agis
BACKGROUND: Angiogenin is a key molecule in the healing process which has been successfully applied in the field of regenerative medicine. The role of angiogenin in dental pulp regeneration is unclear. Here we aimed to reveal the impact of the hypoxia mimetic agent L-mimosine (L-MIM) and hypoxia on angiogenin in the dental pulp. METHODS: Human dental pulp-derived cells (DPC) were cultured in monolayer and spheroid cultures and treated with L-MIM or hypoxia. In addition, tooth slice organ cultures were applied to mimic the pulp-dentin complex...
May 25, 2017: BMC Oral Health
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