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https://www.readbyqxmd.com/read/29139168/hunter-gatherer-dental-pathology-do-historic-accounts-of-aboriginal-australians-correspond-to-the-archeological-record-of-dental-disease
#1
Judith Littleton
OBJECTIVES: Studies of hunter-gatherer oral pathology, particularly in Australia, often focus upon dental wear and caries or assume that historic studies of Aboriginal people reflect the precontact past. Consequently the range of population variation has been underestimated. In this paper dental pathology from human remains from Roonka are compared with a model of dental pathology derived from historic studies. The aim is to identify aspects of dental pathology indicative of regional or intra-population diversity...
November 15, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/29131694/role-of-neuron-glial-interaction-mediated-by-il-1%C3%AE-in-ectopic-tooth-pain
#2
H Komiya, K Shimizu, N Noma, Y Tsuboi, K Honda, K Kanno, K Ohara, M Shinoda, B Ogiso, K Iwata
Although many reports have demonstrated that ectopic pain develops in the orofacial region following tooth pulp inflammation, which often causes misdiagnosis and inappropriate treatment for patients with pulpitis, the precise mechanism remains unknown. In the present study, we hypothesized that the functional interaction between satellite glial cells and neurons mediated by interleukin 1β (IL-1β) in the trigeminal ganglion (TG) is involved in ectopic orofacial pain associated with tooth pulp inflammation...
November 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/29130364/fluorescent-labeling-and-2-photon-imaging-of-mouse-tooth-pulp-nociceptors
#3
A Kadala, P Sotelo-Hitschfeld, Z Ahmad, P Tripal, B Schmid, A Mueller, L Bernal, Z Winter, S Brauchi, U Lohbauer, K Messlinger, J K Lennerz, K Zimmermann
Retrograde fluorescent labeling of dental primary afferent neurons (DPANs) has been described in rats through crystalline fluorescent DiI, while in the mouse, this technique was achieved with only Fluoro-Gold, a neurotoxic fluorescent dye with membrane penetration characteristics superior to the carbocyanine dyes. We reevaluated this technique in the rat with the aim to transfer it to the mouse because comprehensive physiologic studies require access to the mouse as a model organism. Using conventional immunohistochemistry, we assessed in rats and mice the speed of axonal dye transport from the application site to the trigeminal ganglion, the numbers of stained DPANs, and the fluorescence intensity via 1) conventional crystalline DiI and 2) a novel DiI formulation with improved penetration properties and staining efficiency...
November 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/29126633/mechanical-behavior-of-endodontically-restored-canine-teeth-effects-of-ferrule-post-material-and-shape
#4
Pietro Ausiello, Stefano Ciaramella, Massimo Martorelli, Antonio Lanzotti, Fernando Zarone, David C Watts, Antonio Gloria
OBJECTIVE: To assess the effect of a ferrule design with specific post material-shape combinations on the mechanical behavior of post-restored canine teeth. METHODS: Micro-CT scan images of an intact canine were used to create a 3-D tessellated CAD model, from which the shapes of dentin, pulp and enamel were obtained and geometric models of post-endodontically restored teeth were created. Two types of 15mm post were evaluated: a quartz fiber post with conical-tapered shape, and a carbon (C) fiber post with conical-cylindrical shape...
November 7, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29126360/endodontic-treatment-of-canine-teeth-in-a-cynomolgus-monkey-macaca-fascicularis
#5
Caterina Facchini, Ilaria Iacopetti, Eugenio Gaudio, Alessandro Zotti, Massimo Boldrin, Fabio Fante, Franco Mutinelli, Emanuele Cozzi, Giulia Maria De Benedictis
A case of bilateral superior canine tooth pulp necrosis in an 18-year-old male Macaca fascicularis is described . A skull computed tomography scan was performed to confirm the diagnostic suspicion. A successful bilateral endodontic treatment with coronotomy was performed using rotary nickel-titanium instruments. Post-operative dental radiographs confirmed the correct positioning of the sealant. A rapid and excellent clinical recovery was obtained after each surgery. This innovative approach may contribute to improving the quality of root canal treatments provided to non-human primates...
January 1, 2017: Laboratory Animals
https://www.readbyqxmd.com/read/29104379/effect-of-dentin-disinfection-with-2-chlorhexidine-gluconate-and-0-3-iodine-on-dentin-bond-strength-an-in-vitro-study
#6
Nelamakanahalli K Suma, Kukkalli K Shashibhushan, V V Subba Reddy
Objective: Cavity preparation is a surgical procedure that attempts to remove all infected dentin.(1) Bacteria left beneath the filling material is greatest threat to the pulp. To reduce the potential for residual caries development and sensitivity, an antibacterial solution with the ability to disinfect the prepared tooth surface would be of help.(2) So this study was conducted to evaluate and compare the effect of dentin disinfection with 2% chlorhexidine gluconate (Consepsis) and 0...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29103902/morphological-analysis-of-the-lower-second-premolar-for-age-estimation-of-korean-adults
#7
Jeong-Hee Lee, Chena Lee, Bulgan Battulga, Ji Yeon Na, Jae Joon Hwang, Young Hyun Kim, Sang-Sun Han
OBJECTIVES: This study aimed to examine the applicability of the pulp/tooth area ratio in the lower premolar teeth using panoramic radiography in age estimation of Korean adults. METHODS: 402 digital panoramic images of Korean adults between 20 and 78 years were analyzed. Following Cameriere et al.'s method, two observers measured the pulp and tooth areas of the lower second premolar on digital panoramic images, and the ratio of pulp to tooth area in the whole tooth (PTR) was calculated...
October 13, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29100106/l-mimosine-and-hypoxia-enhance-angiopoietin-like-4-production-involving-hypoxia-inducible-factor-1alpha-insights-from-monolayer-and-spheroid-cultures-of-dental-pulp-derived-cells-and-tooth-slice-cultures
#8
Klara Janjić, Umar Alhujazy, Andreas Moritz, Hermann Agis
OBJECTIVE: Angiopoietin-like 4 (Angptl4) is an angiogenesis modulating signaling factor and as such involved in blood vessel formation but also in hard tissue resorption. Here we hypothesized that the hypoxia mimetic agent L-mimosine (L-MIM) and hypoxia stimulate the production of Angptl4 in the dental pulp. MATERIAL AND METHODS: Monolayer and spheroid cultures of primary human dental pulp-derived cells (DPC) were treated with L-MIM or hypoxia. Furthermore, tooth slice cultures were performed...
October 16, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29096680/outcomes-in-randomised-controlled-trials-in-prevention-and-management-of-carious-lesions-a-systematic-review
#9
REVIEW
Colin Levey, Nicola Innes, Falk Schwendicke, Thomas Lamont, Gerd Göstemeyer
BACKGROUND: Inconsistent outcome reporting is one significant hurdle to combining results from trials into systematic reviews. Core outcome sets (COS) can reduce this barrier. The aim of this review was to map outcomes reported in caries prevention and management randomised controlled trials (RCT) as a first step to COS development. We also investigated RCT characteristics and reporting of primary outcomes and sample size calculations. METHODS: PubMed, Embase, Web of Knowledge and Cochrane CENTRAL were systematically searched (1 January 1968 to 25 August 2015)...
November 2, 2017: Trials
https://www.readbyqxmd.com/read/29090391/prevention-of-coronal-discoloration-induced-by-regenerative-endodontic-treatment-in-an-ex-vivo-model
#10
Noushin Shokouhinejad, Mehrfam Khoshkhounejad, Marzieh Alikhasi, Parisa Bagheri, Josette Camilleri
OBJECTIVES: The aim of this study was to assess the effect of sealing the pulp chamber walls with a dentin-bonding agent (DBA) on prevention of discoloration induced by regenerative endodontic procedures (REPs) in an ex vivo model. MATERIALS AND METHODS: Ninety-six bovine incisors were prepared and randomly divided into two groups. In one group, the pulp chamber walls were sealed with DBA before placement of triple antibiotic paste (TAP) containing minocycline inside the root canals, but in the other group, DBA was not applied...
October 31, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29079395/effect-of-low-intensity-pulsed-ultrasound-on-the-expression-of-calcium-ion-transport-related-proteins-during-tertiary-dentin-formation
#11
Jing Zuo, Jiaxiu Zhen, Fei Wang, Yueheng Li, Zhi Zhou
Low-intensity pulsed ultrasound (LIPUS) is known for its positive effect on bone healing and reparative regeneration. This study investigated whether LIPUS affects reparative progression of the tooth and the expression of calcium ion transport-related proteins in odontoblasts and dental pulp cells using a rat dentin-pulp complex injury model. Forty male adult Sprague-Dawley rats underwent cavity preparation in the right maxillary first molar: 20 received LIPUS irradiation on the cavity-prepared tooth; 20 received LIPUS irradiation on the left maxillary first molar...
October 24, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29079055/bleaching-of-a-discolored-tooth-with-retrieval-of%C3%A2-remnants-after-successful-regenerative-endodontics
#12
Aovana Timmerman, Peter Parashos
INTRODUCTION: This report presents the retrieval of remnants from a discolored mandibular right second premolar (tooth #29) of a 17-year-old female after a successful regenerative endodontic procedure (REP). METHODS: The REP was performed in October 2011. Coronal discoloration became of great concern to the patient at a review visit in 2016. A cone-beam computed tomographic scan was taken to investigate the formation of hard tissues within the root canal as well as a region of no calcified tissue formation...
October 24, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29079051/minced-pulp-as-source-of-pulpal-mesenchymal-stem-cells-with-odontogenic-differentiation-capacity
#13
Zhnagrui Liang, Satoshi Kawano, Wei Chen, Moein S Sadrkhani, Chaehwan Lee, Euiseong Kim, Alireza Moshaverinia, Reuben H Kim, Mo Kang
INTRODUCTION: Pulp tissue regeneration is becoming a reality after discovery of mesenchymal stem cells (MSCs) residing in the pulp tissues through various clinical innovations, although MSC transplantation into the pulp space has met with challenges of in vitro cell expansion and cultures. As a way to circumvent the regulatory and technical complexities of in vitro MSC culture, we investigated the use of minced pulp tissues as a source of pulpal MSCs for tissue regeneration. METHODS: We characterized the phenotype of cells explanted from minced pulp (MP), namely MP-derived MSCs (MP-MSCs), compared with dental pulp stem cells (DPSCs) established from pulp tissues by enzyme digestion...
October 24, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29079048/cytokine-expression-of-stem-cells-originating-from-the-apical-complex-and-coronal-pulp-of-immature-teeth
#14
Ki Hoon Joo, Je Seon Song, Seunghye Kim, Hyo-Seol Lee, Mijeong Jeon, Seong-Oh Kim, Jae-Ho Lee
INTRODUCTION: The aim of this study was to measure and compare the expression levels of cytokines from developing apical complex cells (DACCs) and dental pulp stem cells (DPSCs) of the immature tooth. METHODS: DPSC-conditioned medium (CM) and DACCs-CM were obtained from human young teeth, and 174 cytokines secreted from each CM were identified and compared. A cytokine membrane array and enzyme-linked immunosorbent assay were used to measure and compare the expression levels of the cytokines...
October 24, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29075537/pulpo-periodontal-regeneration-management-of-partial-failure-revascularization
#15
Said Dhaimy, Sara Dhoum, Hind Amarir, Hafsa El Merini, Sellama Nadifi, Amal El Ouazzani
The aim of this work is to present a case of management of an open apex on a lower molar by using tissue engineering, with two endodontic procedures in the same tooth. We had to resort to pulp regeneration on the distal root and apexification with MTA on the mesial roots after the failure of regenerative therapy on those ones. The management consisted in scheduling regular follow-ups combined with X-rays. After 24 months, the radiological control has shown pulpo-periodontal regeneration associated with walls thickening and distal root elongation and periapical ad integrum healing...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/29073902/clinical-and-radiographic-evaluation-of-pulpectomy-in-primary-teeth-a-18-months-clinical-randomized-controlled-trial
#16
Xiaoxian Chen, Xinggang Liu, Jie Zhong
BACKGROUND: To avoid untoward changes when primary teeth are replaced by permanent teeth, resorption of the material used in primary teeth root canal filling should occur at the same rate as root resorption. The Aim of this study was to compare the success rates of a mixed primary root canal filling (MPRCF, ingredients: zinc oxide-eugenol [ZOE], iodoform, calcium hydroxide) to those of ZOE and Vitapex in pulpectomised primary molars. METHODS: One hundred and sixty primary molars from 155 children (average age 5...
October 27, 2017: Head & Face Medicine
https://www.readbyqxmd.com/read/29070150/use-of-vital-pulp-therapies-in-primary-teeth-with-deep-caries-lesions
#17
Vineet Dhar, Abdullah A Marghalani, Yasmi O Crystal, Ashok Kumar, Priyanshi Ritwik, Ozlem Tulunoglu, Laurel Graham
PURPOSE: This manuscript presents evidence-based guidance on the use of vital pulp therapies for treatment of deep caries lesions in children. A guideline panel convened by the American Academy of Pediatric Dentistry formulated evidence-based recommendations on three vital pulp therapies: indirect pulp treatment (IPT; also known as indirect pulp cap), direct pulp cap (DPC), and pulpotomy. METHODS: The basis of the guideline's recommendations was evidence from "Primary Tooth Vital Pulp Therapy: A Systematic Review and Meta-Analysis...
September 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29066844/treatment-of-necrotic-teeth-by-apical-revascularization-meta-analysis
#18
Ling He, Juan Zhong, Qimei Gong, Sahng G Kim, Samuel J Zeichner, Lusai Xiang, Ling Ye, Xuedong Zhou, Jinxuan Zheng, Yongxing Liu, Chenyu Guan, Bin Cheng, Junqi Ling, Jeremy J Mao
Each year ~5.4 million children and adolescents in the United States suffer from dental infections, leading to pulp necrosis, arrested tooth-root development and tooth loss. Apical revascularization, adopted by the American Dental Association for its perceived ability to enable postoperative tooth-root growth, is being accepted worldwide. The objective of the present study is to perform a meta-analysis on apical revascularization. Literature search yielded 22 studies following PRISMA with pre-defined inclusion and exclusion criteria...
October 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29064632/the-effects-of-platelet-derived-growth-factor-bb-on-human-dental-pulp-stem-cells-mediated-dentin-pulp-complex-regeneration
#19
Maolin Zhang, Fei Jiang, Xiaochen Zhang, Shaoyi Wang, Yuqin Jin, Wenjie Zhang, Xinquan Jiang
Dentin-pulp complex regeneration is a promising alternative treatment for the irreversible pulpitis caused by tooth trauma or dental caries. This process mainly relies on the recruitment of endogenous or the transplanted dental pulp stem cells (DPSCs) to guide dentin-pulp tissue formation. Platelet-derived growth factor (PDGF), a well-known potent mitogenic, angiogenic, and chemoattractive agent, has been widely used in tissue regeneration. However, the mechanisms underlying the therapeutic effects of PDGF on dentin-pulp complex regeneration are still unclear...
October 24, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/29061351/survival-of-endodontically-treated-roots-teeth-based-on-periapical-health-and-retention-a-10-year-retrospective-cohort-study
#20
Rafael Fernández, Jaime A Cardona, Diego Cadavid, Luis G Álvarez, Felipe A Restrepo
INTRODUCTION: The purpose of this retrospective longitudinal cohort study was to evaluate the outcome of nonsurgical root canal treatment (NSRCT), expressed as survival for both periapical health and retention of roots/teeth, as determined by clinical evaluation, periapical film/digital radiography (PFR/DPR), and cone-beam computed tomography (CBCT) over 10 years, to determine the prognostic factors that influenced successful treatment outcomes. METHODS: A total of 132 teeth (208 roots) with vital pulp received NSRCT at a university clinic...
October 20, 2017: Journal of Endodontics
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