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https://www.readbyqxmd.com/read/28210010/evaluation-and-treatment-of-anemia-in-premature-infants
#1
Edo Hasanbegovic, Nermana Cengic, Snijezana Hasanbegovic, Jasmina Heljic, Ismail Lutolli, Edin Begic
INTRODUCTION: Anemia in preterm infants is the pathophysiological process with greater and more rapid decline in hemoglobin compared to the physiological anemia in infants. There is a need for transfusions and administration of human recombinant erythropoietin. AIM: To determine the frequency of anemia in premature infants at the Pediatric Clinic, University Clinical Center Sarajevo, as well as parameter values in the blood count of premature infants and to explore a relationship between blood transfusions with the advent of intraventricular hemorrhage (determine treatment outcome in preterm infants)...
December 2016: Medical Archives
https://www.readbyqxmd.com/read/28196453/near-infrared-spectroscopy-in-gait-disorders
#2
Vera Gramigna, Giovanni Pellegrino, Antonio Cerasa, Simone Cutini, Roberta Vasta, Giuseppe Olivadese, Iolanda Martino, Aldo Quattrone
Walking is a complex motor behavior with a special relevance in clinical neurology. Many neurological diseases, such as Parkinson's disease and stroke, are characterized by gait disorders whose neurofunctional correlates are poorly investigated. Indeed, the analysis of real walking with the standard neuroimaging techniques poses strong challenges, and only a few studies on motor imagery or walking observation have been performed so far. Functional near-infrared spectroscopy (fNIRS) is becoming an important research tool to assess functional activity in neurological populations or for special tasks, such as walking, because it allows investigating brain hemodynamic activity in an ecological setting, without strong immobility constraints...
January 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28194196/assessment-of-hemodialysis-adequacy-and-its-relationship-with-individual-and-personal-factors
#3
Ozra Rezaiee, Nahid Shahgholian, Shahrzad Shahidi
BACKGROUND: Hemodialysis is the most common renal replacement therapy in the world, and hemodialysis adequacy is an important and influencial factor in the reduction of various complications experienced by these patients. Multiple factors influence hemodialysis adequacy. This study was conducted to determine hemodialysis adequacy and its relationship with individual and personal factors in patients undergoing hemodialysis in three hemodialysis centers of Isfahan, Iran. MATERIALS AND METHODS: This descriptive, cross-sectional study was conducted in partnership with 202 patients undergoing hemodialysis in three hemodialysis centers of Isfahan...
November 2016: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28192004/psychological-resources-and-glucoregulation-in-japanese-adults-findings-from-midja
#4
Jennifer Morozink Boylan, Vera K Tsenkova, Yuri Miyamoto, Carol D Ryff
OBJECTIVE: To examine associations between glucoregulation and 3 categories of psychological resources: hedonic well-being (i.e., life satisfaction, positive affect), eudaimonic well-being (i.e., personal growth, purpose in life, ikigai), and interdependent well-being (i.e., gratitude, peaceful disengagement, adjustment) among Japanese adults. The question is important given increases in rates of type 2 diabetes in Japan in recent years, combined with the fact that most prior studies linking psychological resources to better physical health have utilized Western samples...
February 13, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28187318/effect-of-maternal-cells-transferred-with-colostrum-on-the-health-of-neonate-calves
#5
Sylvia Marquart Fontes Novo, Juliana Fraça Dos Reis Costa, Camila Costa Baccili, Natália Meirelles Sobreira, Bruno Toledo Silva, Pamella Lorenci de Oliveira, David John Hurley, Viviani Gomes
The objective of this research was to evaluate the influence of cells from colostrum on the health of neonate calves. Animals were distributed in 2 groups: COL+ (n=9) which received fresh colostrum from their own damns; and COL- (n=10) which received frozen colostrums from donors. Heifers were assessed before colostrum intake - D0; D2; D7; D14; D21 and D28. Heifers were monitored by clinical examination, hematological profile and serum iron. COL- had a higher diarrhea intensity score (typically 3) on D7. Moreover, a single case each of bronchopneumonia and navel inflammation were observed in COL- calves...
January 27, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28183818/normalization-of-hemoglobin-based-oxygen-carrier-201-induced-vasoconstriction-roles-of-nitric-oxide-scavenging-and-endothelin
#6
Yannick J Taverne, Daphne P M de Wijs-Meijler, Maaike Te Lintel Hekkert, Paula F Moon-Massat, Greg P Dubé, Dirk Jan Duncker, Daphne Merkus
BACKGROUND: Hemoglobin-based oxygen carrier (HBOC)-201 is a cell-free modified hemoglobin solution potentially facilitating oxygen uptake and delivery in cardiovascular disorders and hemorrhagic shock. Clinical use has been hampered by vasoconstriction in the systemic and pulmonary beds. Therefore we aimed to 1) determine the possibility of counteracting HBOC-201-induced pressor effects with adenosine (ADO), 2) assess the potential roles of nitric oxide (NO) scavenging, reactive oxygen species (ROS) and endothelin (ET) in mediating the observed vasoconstriction and 3) compare these effects in resting and exercising swine...
February 9, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28182863/randomized-controlled-trial-of-a-community-health-worker-self-management-support-intervention-among-low-income-adults-with-diabetes-seattle-washington-2010-2014
#7
Karin Nelson, Leslie Taylor, Julie Silverman, Meghan Kiefer, Paul Hebert, Dan Lessler, James Krieger
INTRODUCTION: Community health workers (CHWs) can improve diabetes outcomes; however, questions remain about translating research findings into practical low-intensity models for safety-net providers. We tested the effectiveness of a home-based low-intensity CHW intervention for improving health outcomes among low-income adults with diabetes. METHODS: Low-income patients with glycated hemoglobin A1c (HbA1c) of 8.0% or higher in the 12 months before enrollment from 3 safety-net providers were randomized to a 12-month CHW-delivered diabetes self-management intervention or usual care...
February 9, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28182094/hemoglobins-likely-function-as-peroxidase-in-blood-clam-tegillarca-granosa-hemocytes
#8
Sufang Wang, Xiaopei Yu, Zhihua Lin, Shunqin Zhang, Liangyi Xue, Qinggang Xue, Yongbo Bao
Hemoglobins are a group of respiratory proteins principally functioning in transport of oxygen and carbon dioxide in red blood cells of all vertebrates and some invertebrates. The blood clam T. granosa is one of the few invertebrates that have hemoglobin-containing red hemocytes. In the present research, the peroxidase activity of T. granosa hemoglobins (Tg-Hbs) was characterized and the associated mechanism of action was deciphered via structural comparison with other known peroxidases. We detected that purified Tg-Hbs catalyzed the oxidation of phenolic compounds in the presence of exogenous H2O2...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/28182023/a-randomized-single-blind-parallel-group-study-comparing-monoherbal-formulation-containing-holarrhena-antidysenterica-extract-with-mesalamine-in-chronic-ulcerative-colitis-patients
#9
Sarika Johari, Tejal Gandhi
BACKGROUND: Incidences of side effects and relapses are very common in chronic ulcerative colitis patients after termination of the treatment. AIMS AND OBJECTIVES: This study aims to compare the treatment with monoherbal formulation of Holarrhena antidysenterica with Mesalamine in chronic ulcerative colitis patients with special emphasis to side effects and relapse. SETTINGS AND DESIGN: Patients were enrolled from an Ayurveda Hospital and a private Hospital, Gujarat...
July 2016: Ancient Science of Life
https://www.readbyqxmd.com/read/28178945/comparative-genomics-of-canine-hemoglobin-genes-reveals-primacy-of-beta-subunit-delta-in-adult-carnivores
#10
Sara Zaldívar-López, Jennie L Rowell, Elise M Fiala, Isain Zapata, C Guillermo Couto, Carlos E Alvarez
BACKGROUND: The main function of hemoglobin (Hb) is to transport oxygen in the circulation. It is among the most highly studied proteins due to its roles in physiology and disease, and most of our understanding derives from comparative research. There is great diversity in Hb gene evolution in placental mammals, mostly in the repertoire and regulation of the β-globin subunits. Dogs are an ideal model in which to study Hb genes because: 1) they are members of Laurasiatheria, our closest relatives outside of Euarchontoglires (including primates, rodents and rabbits), 2) dog breeds are isolated populations with their own Hb-associated genetics and diseases, and 3) their high level of health care allows for development of biomedical investigation and translation...
February 8, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28178698/dipeptidyl-peptidase-4-inhibitors-in-chronic-kidney-disease-a-systematic-review-of-randomized-clinical-trials
#11
Simon R Walker, Paul Komenda, Suhail Khojah, Wafa Al-Tuwaijri, Kerry MacDonald, Brett Hiebert, Neil Tangri, Stewart W D Nadurak, Thomas W Ferguson, Claudio Rigatto, Navdeep Tangri
BACKGROUND: Chronic kidney disease (CKD) is common in patients with type 2 diabetes mellitus (T2DM) and limits therapeutic options. Dipeptidyl peptidase-4 (DPP-4) inhibitors represent a novel class of oral glucose-lowering agents and are known to be safe and effective in the general population. METHODS: We searched Cochrane, EMBASE, and PubMed from the time of their inception until March 2015. We included randomized controlled trials analyzing the efficacy (change in hemoglobin A1C [HbA1C]) and safety of DPP-4 agents in individuals with reduced kidney function (estimated glomerular filtration rate <60 mL/min/1...
February 9, 2017: Nephron
https://www.readbyqxmd.com/read/28176886/assessment-of-channeling-bias-among-initiators-of-glucose-lowering-drugs-a-uk-cohort-study
#12
Mikkel Z Ankarfeldt, Brian L Thorsted, Rolf Hh Groenwold, Erpur Adalsteinsson, M Sanni Ali, Olaf H Klungel
BACKGROUND: Channeling bias may occur when a newly marketed drug and an established drug, despite similar indications, are prescribed to patients with different prognostic characteristics (ie, confounding). AIM: To investigate channeling bias and its impact on relative effectiveness of glucagon-like peptide-1 (GLP-1) analogs versus basal insulin and dipeptidyl peptidase-4 inhibitors (DPP-4i) versus sulfonylurea. METHODS: In the UK Clinical Practice Research Datalink, patients with type 2 diabetes initiating treatment between 2006 and 2015 were included...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28166278/gut-dysbiosis-is-associated-with-metabolism-and-systemic-inflammation-in-patients-with-ischemic-stroke
#13
Kazuo Yamashiro, Ryota Tanaka, Takao Urabe, Yuji Ueno, Yuichiro Yamashiro, Koji Nomoto, Takuya Takahashi, Hirokazu Tsuji, Takashi Asahara, Nobutaka Hattori
The role of metabolic diseases in ischemic stroke has become a primary concern in both research and clinical practice. Increasing evidence suggests that dysbiosis is associated with metabolic diseases. The aim of this study was to investigate whether the gut microbiota, as well as concentrations of organic acids, the major products of dietary fiber fermentation by the gut microbiota, are altered in patients with ischemic stroke, and to examine the association between these changes and host metabolism and inflammation...
2017: PloS One
https://www.readbyqxmd.com/read/28164750/educational-strategies-of-diabetes-group-medical-visits-a-review
#14
Julienne K Kirk, Hannah Marie Devoid, Carmen Strickland
BACKGROUND: Diabetes is a demanding disease that is growing in prevalence. Improved outcomes for patients with diabetes are highly dependent on self-management skills and the ability to make lifestyle changes. Innovative healthcare approaches are necessary to meet these specific patient needs. A group care medical visit (GMV) combines diabetes check-ups with diabetes education in a supportive and patient centered environment that promotes effective self-management. GMVs are associated with improved diabetes outcomes including hemoglobin A1C, weight, and self-efficacy; however details of the methods by which content is delivered to achieve these outcomes remain vague...
February 3, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28162037/does-length-of-relationship-or-gender-predict-response-to-behavioral-diabetes-intervention
#15
Jonathan Sandberg, Jeremy B Yorgason, Lawrence Fisher, Ruth S Weinstock, Danielle Hessler, Jacqueline Dimmock, Paula M Trief
Purpose The purpose of the study was to determine, through secondary analysis, whether the length of a couple's relationship and the participants' gender are associated with glycemic response to a type 2 diabetes (T2D) behavioral couples-based intervention. Methods A randomized trial was conducted to test the impact of a couples-level, telephone-based behavioral intervention on hemoglobin A1C in patients with T2D. One hundred and four patients and partners participated in the couples intervention arm, and 94 individuals participated in the individual arm...
February 1, 2017: Diabetes Educator
https://www.readbyqxmd.com/read/28149928/evening-and-morning-alterations-in-obstructive-sleep-apnea-red-blood-cell-proteome
#16
Amélia Feliciano, Fátima Vaz, Cristina Valentim-Coelho, Vukosava M Torres, Rita Silva, Vesna Prosinecki, Bruno M Alexandre, Andreia Almeida, Catarina Almeida-Marques, Ana S Carvalho, Rune Matthiesen, Atul Malhotra, Paula Pinto, Cristina Bárbara, Deborah Penque
This article presents proteomics data referenced in [1] Using proteomics-based evaluation of red blood cells (RBCs), we have identified differentially abundant proteins associated with Obstructive Sleep Apnea Syndrome (OSA). RBCs were collected from peripheral blood of patients with moderate/severe OSA or snoring at pre- (evening) and post-night (morning) polysomnography, so that proteome variations between these time points could be assessed. RBC cytoplasmic fraction depleted of hemoglobin, using Hemovoid(™) system, were analyzed by two-dimensional fluorescence difference gel electrophoresis (2D-DIGE), the 2D image software-based analyzed and relevant differentially abundant proteins identified by mass spectrometry (MS)...
April 2017: Data in Brief
https://www.readbyqxmd.com/read/28146680/prefrontal-hemodynamics-of-physical-activity-and-environmental-complexity-during-cognitive-work
#17
Ryan McKendrick, Ranjana Mehta, Hasan Ayaz, Melissa Scheldrup, Raja Parasuraman
OBJECTIVE: The aim of this study was to assess performance and cognitive states during cognitive work in the presence of physical work and in natural settings. BACKGROUND: Authors of previous studies have examined the interaction between cognitive and physical work, finding performance decrements in working memory. Neuroimaging has revealed increases and decreases in prefrontal oxygenated hemoglobin during the interaction of cognitive and physical work. The effect of environment on cognitive-physical dual tasking has not been previously considered...
February 2017: Human Factors
https://www.readbyqxmd.com/read/28141793/sex-specific-associations-between-cerebrovascular-blood-pressure-autoregulation-and-cardiopulmonary-injury-in-neonatal-encephalopathy-and-therapeutic-hypothermia
#18
Raul Chavez-Valdez, Matthew O'Connor, Jamie Perin, Michael Reyes, Jillian Armstrong, Charlamaine Parkinson, Maureen Gilmore, Jacky Jennings, Frances J Northington, Jennifer K Lee
BACKGROUND: Cardiopulmonary injury is common in neonatal encephalopathy, but the link with cerebrovascular dysfunction is unknown. We hypothesized that cerebral autoregulation is associated with cardiopulmonary injury in neonates treated with therapeutic hypothermia (TH) for neonatal encephalopathy. METHODS: The cerebral hemoglobin volume index (HVx) from near-infrared spectroscopy was used to identify the mean arterial blood pressure (MAP) with optimal autoregulatory vasoreactivity (MAPOPT)...
January 31, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28139954/a-need-for-dynamic-hematology-and-serum-biochemistry-reference-tools-novel-use-of-sine-wave-functions-to-produce-seasonally-varying-reference-curves-in-platypuses-ornithorhynchus-anatinus
#19
James W Macgregor, Carly S Holyoake, Joanne H Connolly, Ian D Robertson, Patricia A Fleming, Kristin S Warren
Seasonal changes in hematology and serum biochemistry results, described by separate reference intervals for different seasons, have been reported in many animals. We developed a novel method to investigate seasonal variation in values and a reference tool (the reference curve) based on sine wave functions that, for suitable variables, represents data more appropriately than a fixed reference interval. We applied these techniques to values observed in blood samples from 126 adult wild platypuses ( Ornithorhynchus anatinus ) (58 females and 68 males)...
January 31, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28138861/zinc-s-role-in-the-glycemic-control-of-patients-with-type-2-diabetes-a-systematic-review
#20
REVIEW
Gabrielli Barbosa de Carvalho, Paula Nascimento Brandão-Lima, Carla Soraya Costa Maia, Kiriaque Barra Ferreira Barbosa, Liliane Viana Pires
Past research has shown the importance of zinc in several metabolic processes, such as the glucidic metabolism. The present systematic review aims to discuss zinc's participation in the glycemic control of type 2 diabetes mellitus (DM2) patients. In order to accomplish that, a systematic search was performed in the Pubmed database using the following indexed and theme-related descriptors: "zinc" AND "type 2 diabetes mellitus", AND MeSH terms related to glycemic control combined with the boolean operator OR...
January 30, 2017: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
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