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hypomagnesemia peritoneal dialysis

Shihming Tsai, Huiping Zhao, Bei Wu, Li Zuo, Mei Wang
BACKGROUND/AIMS: Both hypomagnesemia and hypermagnesemia have been associated with cardiovascular diseases, bone diseases, and mortality in dialysis patients. We aimed to investigate the prevalence of and influencing factors for abnormal serum Mg levels in patients on peritoneal dialysis (PD). METHODS: A cross-sectional study in Peking University People's Hospital recorded the demographic information, clinical characteristics, and laboratory data. Data were assessed and compared with the results from 2 other studies in China...
December 14, 2017: Blood Purification
Xiao Yang, Melissa Soohoo, Elani Streja, Matthew B Rivara, Yoshitsugu Obi, Scott V Adams, Kamyar Kalantar-Zadeh, Rajnish Mehrotra
BACKGROUND: Prior studies have shown the association of low serum magnesium levels with adverse health outcomes in patients undergoing hemodialysis. There is a paucity of such studies in patients undergoing peritoneal dialysis (PD). STUDY DESIGN: Cohort study. SETTING & PARTICIPANTS: 10,692 patients treated with PD from January 1, 2007, through December 31, 2011, in facilities operated by a single large dialysis organization in the United States...
October 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Kedan Cai, Qun Luo, Zhiwei Dai, Beixia Zhu, Jinping Fei, Congping Xue, Dan Wu
OBJECTIVE: Hypomagnesemia has been associated with an increase in mortality among the general population as well as patients with chronic kidney disease or those on hemodialysis. However, this association has not been thoroughly studied in patients undergoing peritoneal dialysis. The aim of this study was to evaluate the association between serum magnesium concentrations and all-cause and cardiovascular mortalities in peritoneal dialysis patients. METHODS: This single-center retrospective study included 253 incident peritoneal dialysis patients enrolled between July 1, 2005 and December 31, 2014 and followed to June 30, 2015...
2016: PloS One
James Goya Heaf
PURPOSE: The purpose of this paper was to review the literature concerning the treatment of chronic kidney disease-mineral bone disorder (CKD-MBD) in the elderly peritoneal dialysis (PD) patient. RESULTS: Chronic kidney disease-mineral bone disorder is a major problem in the elderly PD patient, with its associated increased fracture risk, vascular calcification, and accelerated mortality fracture risk. Peritoneal dialysis, however, bears a lower risk than hemodialysis (HD)...
November 2015: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Hongjian Ye, Xiaodan Zhang, Qunying Guo, Naya Huang, Haiping Mao, Xueqing Yu, Xiao Yang
No abstract text is available yet for this article.
July 2013: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Parham Amirmokri, Patti Morgan, Bahar Bastani
BACKGROUND: Malnutrition and gastrointestinal (GI) losses are frequently encountered in peritoneal dialysis patients, leading to hypokalemia and hypomagnesemia. Oral supplementation is limited by patients' compliance, as well as GI side effects. METHODS: Among the 27 patients on continuous cyclic peritoneal dialysis (CCPD) in whom we had one-year data, 15 (55%) were on oral potassium (K) supplements and 10 (37%) were on oral magnesium (Mg) supplements. Hypokalemia and hypomagnesemia persisted in 3 (11%) patients despite oral supplementation...
2007: Renal Failure
Mingxin Wei, Khaled Esbaei, Joanne Bargman, Dimitrios G Oreopoulos
Secondary hyperparathyroidism is present in most patients with end-stage renal disease and has been linked to uremic bone disease, vascular calcification, and mortality. Current literature suggests an association between hypomagnesemia and cardiovascular disease in the general population. We reviewed all published studies on the relationship between serum magnesium and parathyroid hormone and the relationship between serum Mg and vascular calcification in dialysis patients. Of these, 10 of 12 studies of patients on hemodialysis and 4 of 5 studies of patients on peritoneal dialysis showed a significantinverse relationship between serum Mg and serum intact parathyroid hormone...
May 2006: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Kostas P Katopodis, Elli L Koliousi, Emilios K Andrikos, Michael V Pappas, Moses S Elisaf, Kostas C Siamopoulos
We carried out this retrospective study to examine the magnesium status of our chronic ambulatory peritoneal dialysis (CAPD) patients dialyzed with 0.75 mmol/L (group I) or 0.50 mmol/L (group II) magnesium peritoneal dialysis solution. A total of 34 anuric patients on CAPD (age:31-72 years; duration of CAPD:7-74 months) were studied. None of them received magnesium-containing phosphate binders or vitamin D. Biochemical parameters including magnesium, calcium, phosphate, parathormone, and albumin were measured in all patients...
September 2003: Artificial Organs
Min Seok Cho, Kyun Sang Lee, Youn Kyoung Lee, Seong Kwon Ma, Jeong Hee Ko, Soo Wan Kim, Nam Ho Kim, Ki Chul Choi
BACKGROUND: Patients on continuous ambulatory peritoneal dialysis (CAPD) have increased risk of low-turnover bone disease and relative hypoparathyroidism. Recently, it has been believed that magnesium plays an important role in regulating secretion of parathyroid hormone (PTH). The aim of this study was to evaluate the relationship between serum PTH and serum magnesium as a factor increasing the frequency of relative hypoparathyroidism. METHODS: We analyzed the data of 56 patients who had been on CAPD for more than 6 months without any significant problems...
June 2002: Korean Journal of Internal Medicine
D R Duerksen, N Papineau
BACKGROUND AND METHODS: Chronic renal failure frequently is complicated by elevations in serum potassium, phosphate, and magnesium. Consequently, parenteral nutrition (PN) solutions used to treat malnourished patients with chronic renal failure usually are prepared with little supplementation of these cations. Four malnourished patients with chronic renal failure and electrolyte abnormalities are reported. RESULTS: Four patients developed significant hypophosphatemia 3 to 5 days after starting PN...
March 1998: JPEN. Journal of Parenteral and Enteral Nutrition
W C Lye, S O Leong
Neuromuscular complications, including tetany and laryngeal spasm, are recognized complications of hypocalcemia and hypomagnesemia. We present a continuous ambulatory peritoneal dialysis patient with hypomagnesemia who developed hyperphosphatemia and profound hypocalcemia after oral phosphate replacement for severe hypophosphatemia. The combination of hypocalcemia and hypomagnesemia resulted in life-threatening bilateral vocal cord paralysis. Phosphate replacement should be determined and given cautiously, particularly in patients with renal failure and concomitant electrolyte disturbances...
January 1994: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
M S Markell, B T Altura, Y Sarn, B G Delano, O Ifudu, E A Friedman, B M Altura
Serum total magnesium (TMg) measurements in dialysis patients are variable, with some groups reporting hypermagnesemia and some hypomagnesemia. It had not been possible to measure the biologically active fraction, ionized magnesium (IMg2+). The authors utilized an ion-selective electrode to measure IMg in 26 hemodialysis patients and 10 peritoneal dialysis (CAPD) patients and compared the results with those from 66 age matched control subjects. Dialysate magnesium was 0.375 mM/L for the hemodialysis and 0.25 mM/L for the CAPD patients...
July 1993: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
A A Ejaz, A P McShane, V C Gandhi, D J Leehey, T S Ing
OBJECTIVE: Previous studies have shown a decrease in serum magnesium (Mg) concentration when continuous ambulatory peritoneal dialysis (CAPD) patients previously maintained on a 1.0-1.2 mEq/L Mg peritoneal dialysis solution (PDS) were dialyzed with a 0.5 mEq/L Mg PDS. However, the prevalence of hypomagnesemia in CAPD patients dialyzed with low-Mg PDS is unknown. DESIGN: A retrospective study to determine the prevalence of hypomagnesemia and the factors associated with its occurrence in CAPD patients dialyzed using a 0...
1995: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
H N Tay, H K Yap, B Murugasu, T C Quah, S H Tay, J W Lim
Complications of chemotherapy for a synovial sarcoma in an eight-year old boy included cisplatinum nephrotoxicity and adriamycin cardiotoxicity. The resultant renal failure and fluid overload necessitated peritoneal dialysis. Intractable hypomagnesemia was also a prominent feature.
1990: Journal of the Singapore Paediatric Society
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