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https://www.readbyqxmd.com/read/29346686/in-the-hands-of-doctors-touch-and-trust-in-medical-care
#1
William Ventres
No abstract text is available yet for this article.
January 2018: Family Medicine
https://www.readbyqxmd.com/read/29346683/strigolactones-mediators-of-osmotic-stress-responses-with-a-potential-for-agrochemical-manipulation-of-crop-resilience
#2
Francesca Cardinale, Paolo Korwin Krukowski, Andrea Schubert, Ivan Visentin
After quickly touching upon general aspects of strigolactones biology and functions, including structure, synthesis and perception, this review focuses on the role and regulation of the strigolactone pathway during osmotic stress, in light of the most recent research developments. We discuss available data on organ-specific dynamics of strigolactone synthesis and interaction with abscisic acid in the acclimatization response, with emphasis on the ecophysiological implications of the effects on the stomatal closure process...
January 15, 2018: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29344038/an-evaluation-of-acupressure-on-the-sanyinjiao-sp6-and-hugo-li4-points-on-the-pain-severity-and-length-of-labor-a-systematic-review-and-meta-analysis-study
#3
REVIEW
Fatemeh Najafi, Molouk Jaafarpour, Kourosh Sayehmiri, Javaher Khajavikhan
Background: In this study, the effects of SP6 and LI4 acupressure on the pain severity and length of labor are examined. Materials and Methods: This systematic review and meta-analysis study was performed on articles published in 2004-2015. The articles, published in the English and Farsi languages, related to the effects of acupressure on the SP6 and LI4 points on the length and pain severity of labor. Data were collected by searching medical databases, including PubMed, ISI, MagIran, Google Scholar, Iran Medex, SID, Irandoc, and EMBASE, for relevant material...
January 2018: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/29343895/why-borrow-from-peter-when-paul-can-afford-it-reverse-homodigital-artery-flap-for-fingertip-reconstruction
#4
Narayanamurthy Sundaramurthy, Surya Rao Rao Venkata Mahipathy, Alagar Raja Durairaj
Background: Fingertip injuries that are complicated by pulp loss, bone or tendon exposure will need a flap cover. Cross finger flap is commonly used to cover such defects. However, patients are apprehensive about injuring the uninjured finger as a donor site. Reverse homodigital artery flap (RHAF) can provide reliable vascularised cover to such defects. Aims: This study aims to assess the functional and aesthetic outcomes along with the patient satisfaction of RHAFs done for fingertip defects...
May 2017: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/29343066/kane-fermion-in-two-dimensional-%C3%AF-conjugated-bis-iminothiolato-nickel-monolayer
#5
Aizhu Wang, Xinrui Zhao, Mingwen Zhao, Xiaoming Zhang, Yuan Ping Feng, Feng Liu
Massless Kane fermion revealed in zinc-blende semiconductors has recently gained interest in the broad study of relativistic materials. In particular, two-dimensional (2D) Kane fermion was expected as a hybrid of a pseudospin-1 and -1/2 Dirac fer-mions. Based on first-principles calculations, we demonstrated that 2D Kane fermion can be realized in a recently-synthesized metal-organic framework, namely bis(iminothiolato)nickel monolayer. A slight compression takes the system from a sem-imetal to a semiconductor...
January 17, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29342146/a-theory-of-how-active-behavior-stabilises-neural-activity-neural-gain-modulation-by-closed-loop-environmental-feedback
#6
Christopher L Buckley, Taro Toyoizumi
During active behaviours like running, swimming, whisking or sniffing, motor actions shape sensory input and sensory percepts guide future motor commands. Ongoing cycles of sensory and motor processing constitute a closed-loop feedback system which is central to motor control and, it has been argued, for perceptual processes. This closed-loop feedback is mediated by brainwide neural circuits but how the presence of feedback signals impacts on the dynamics and function of neurons is not well understood. Here we present a simple theory suggesting that closed-loop feedback between the brain/body/environment can modulate neural gain and, consequently, change endogenous neural fluctuations and responses to sensory input...
January 17, 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29342092/metabolic-alterations-in-cancer-cells-and-the-emerging-role-of-oncometabolites-as-drivers-of-neoplastic-change
#7
REVIEW
Zhengqiu Zhou, Elochukwu Ibekwe, Yevgen Chornenkyy
The mitochondrion is an important organelle and provides energy for a plethora of intracellular reactions. Metabolic dysregulation has dire consequences for the cell, and alteration in metabolism has been identified in multiple disease states-cancer being one. Otto Warburg demonstrated that cancer cells, in the presence of oxygen, undergo glycolysis by reprogramming their metabolism-termed "aerobic glycolysis". Alterations in metabolism enable cancer cells to gain a growth advantage by obtaining precursors for macromolecule biosynthesis, such as nucleic acids and lipids...
January 17, 2018: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29340549/teaching-model-for-evaluation-of-the-ability-and-competence-progress-in-endosuture-in-surgical-skill-laboratory
#8
Luiz Gonzaga de Moura-Júnior, Almino Ramos, Josemberg Marins Campos, Álvaro Antônio Ferraz, Hermano Ângelo Lima Rocha, Grijalva Otávio Costa
BACKGROUND: Laparoscopic manual suturing is probably the most difficult skill to be acquired in minimally invasive surgery. However, laparoscopic exercise endo-sutures can be learned with a simulator and are of great practical importance and clinical applicability, absorbing concepts that are immediately transferred to the operating room. AIM: To assess the progression of skills competence in endo-sutures through realistic simulation model of systematized education...
October 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/29340386/on-chip-functional-neuroimaging-with-mechanical-stimulation-in-caenorhabditis-elegans-larvae-for-studying-development-and-neural-circuits
#9
Yongmin Cho, David N Oakland, Sol Ah Lee, William R Schafer, Hang Lu
Mechanosensation is fundamentally important for the abilities of an organism to experience touch, hear sounds, and maintain balance. Caenorhabditis elegans is a powerful system for studying mechanosensation as this worm is well suited for in vivo functional imaging of neurons. Many years of research using labor-intensive methods have generated a wealth of knowledge about mechanosensation in C. elegans, and the recent microfluidic-based platforms continue to push the boundary for this field. However, developmental aspects of sensory biology, including mechanosensation, are still not fully understood...
January 17, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29339793/skin-inspired-highly-stretchable-and-conformable-matrix-networks-for-multifunctional-sensing
#10
Qilin Hua, Junlu Sun, Haitao Liu, Rongrong Bao, Ruomeng Yu, Junyi Zhai, Caofeng Pan, Zhong Lin Wang
Mechanosensation electronics (or Electronic skin, e-skin) consists of mechanically flexible and stretchable sensor networks that can detect and quantify various stimuli to mimic the human somatosensory system, with the sensations of touch, heat/cold, and pain in skin through various sensory receptors and neural pathways. Here we present a skin-inspired highly stretchable and conformable matrix network (SCMN) that successfully expands the e-skin sensing functionality including but not limited to temperature, in-plane strain, humidity, light, magnetic field, pressure, and proximity...
January 16, 2018: Nature Communications
https://www.readbyqxmd.com/read/29338489/multimodal-physiotherapy-treatment-based-on-a-biobehavioral-approach-for-patients-with-chronic-cervico-craniofacial-pain-a-prospective-case-series
#11
Fernando Marcos-Martín, Luis González-Ferrero, Noelia Martín-Alcocer, Alba Paris-Alemany, Roy La Touche
The purpose of this prospective case series was to observe and describe changes in patients with chronic cervico-craniofacial pain of muscular origin treated with multimodal physiotherapy based on a biobehavioral approach. Nine patients diagnosed with chronic myofascial temporomandibular disorder and neck pain were treated with 6 sessions over the course of 2 weeks including: (1) orthopedic manual physiotherapy (joint mobilizations, neurodynamic mobilization, and dynamic soft tissue mobilizations); (2) therapeutic exercises (motor control and muscular endurance exercises); and (3) patient education...
January 17, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29337699/associations-between-nurse-guided-variables-and-plasma-oxytocin-trajectories-in-premature-infants-during-initial-hospitalization
#12
Ashley Weber, Tondi M Harrison, Loraine Sinnott, Abigail Shoben, Deborah Steward
BACKGROUND: Oxytocin (OT) is a social hormone that may help researchers understand how nurse-guided interventions during initial infant hospitalization, such as supporting human milk expression, promoting comforting touch, and reducing exposure to stressors, affect preterm brain development. PURPOSE: To determine whether factors related to human milk, touch, or stressor exposure are related to plasma OT trajectories in premature infants. METHODS: Plasma from 33 premature infants, born gestational ages 25 to 28 6/7 weeks, was collected at 14 days of life and then weekly until 34 weeks' corrected gestational age (CGA)...
January 15, 2018: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/29336336/-training-program-in-urological-laparoscopic-surgery-future-perspective
#13
Alfredo Aguilera Bazán, Juan Gómez Rivas, Estefanía Linares-Espinós, Mario Alvarez-Maestro, Luis Martínez-Piñeiro
Nowadays in urology, laparoscopic surgery is a reality that implies a very high percentage of the daily surgical activity. The interest in laparoscopy in urological pathology is undeniable, and the advantages for our patients with this approach are clear in most cases. But how do we deal with learning curve of this technique? What is the difficulty in laparoscopy training? What future perspectives might offer this approach? Difficulties in learning laparoscopy are easily identified and clear. The loss of the image in 3 dimensions, loss of touch, great dependence on surgical instruments, among others...
January 2018: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29336303/keratinocytes-mediate-innocuous-and-noxious-touch-via-atp-p2x4-signaling
#14
Francie Moehring, Ashley M Cowie, Anthony D Menzel, Andy D Weyer, Michael Grzybowski, Thiago Arzua, Aron M Geurts, Oleg Palygin, Cheryl L Stucky
The first point of our body's contact with tactile stimuli (innocuous and noxious) is the epidermis, the outermost layer of skin that is largely composed of keratinocytes. Here, we sought to define the role that keratinocytes play in touch sensation in vivo and ex vivo. We show that optogenetic inhibition of keratinocytes decreases behavioral and cellular mechanosensitivity. These processes are inherently mediated by ATP signaling, as demonstrated by complementary cutaneous ATP release and degradation experiments...
January 16, 2018: ELife
https://www.readbyqxmd.com/read/29336231/a-new-and-universal-classification-system-of-skin-substitutes-inspired-by-factorial-design
#15
Evan Davison-Kotler, Vaibhav Sharma, Norbert Kang, Elena García-Gareta
The complexity of the dermal layer of skin means that damage to this section can result in permanent impairment of function. Partial or total dermal loss is a feature of deep burns and chronic wounds such as pressure sores or diabetic ulcers. The issues posed by traditional skin grafts have led to substantial research being carried out in the fields of tissue engineering and biomaterials science to develop a vast array of alternative skin substitutes. Given the large number of different materials, manufacturing methods, and techniques for implementation described for artificial skin substitutes, many classification systems have been created to simplify their categorization...
January 16, 2018: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/29335352/discrete-modules-and-mesoscale-functional-circuits-for-thermal-nociception-within-primate-s1-cortex
#16
Pai-Feng Yang, Ruiqi Wu, Tung-Lin Wu, Zhaoyue Shi, Li Min Chen
This study addresses one long-standing question of whether functional separations are preserved for somatosensory modalities of touch, heat and cold nociception within primate primary somatosensory (S1) cortex. This information is critical for understanding how the nature of pain is represented in the primate brain. Using a combination of submillimeter-resolution fMRI and microelectrode local field potential (LFP) and spike recordings, we identified spatially-segregated cortical zones for processing touch, nociceptive heat and cold stimuli in somatotopically appropriate areas 3a, 3b, 1, and 2 of S1 in male monkeys...
January 15, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29334937/perspectives-on-setting-limits-for-rf-contact-currents-a-commentary
#17
REVIEW
Richard A Tell, Christopher A Tell
BACKGROUND: Limits for exposure to radiofrequency (RF) contact currents are specified in the two dominant RF safety standards and guidelines developed by the Institute of Electrical and Electronics Engineers (IEEE) and the International Commission on Non-Ionizing Radiation Protection (ICNIRP). These limits are intended to prevent RF burns when contacting RF energized objects caused by high local tissue current densities. We explain what contact currents are and review some history of the relevant limits with an emphasis on so-called "touch" contacts, i...
January 15, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29334138/move-knife-tip-on-the-thoracic-aorta-a-high-risk-submucosal-tunneling-endoscopic-resection-ster-procedure-for-a-puzzle-submucosal-mass-in-esophagus-with-video
#18
Wengang Zhang, Ningli Chai, Enqiang Linghu
A 43-year-old men was found an esophageal submucosal mass at 26 cm from the incisors; and preoperative EUS suggested a leiomyoma in MP layer. STER1, 2 , deriving from POEM3, 4 , was performed, and an inverse T incision5 was carried out firstly. Subsequently, a submucosal tunnel was established extending to the distal esophagus; and a mass, covered with MP tissue, was discovered (Figure 1); particularly, the mass was going up and down rhythmically, and had soft touch; given the possibility of aorta compression or cyst, ECDUS was conducted and uncovered a homogeneous hypoechoic lesion, just against thoracic aorta (Figure 2)...
January 15, 2018: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29333688/infant-brain-responses-to-felt-and-observed-touch-of-hands-and-feet-an-meg-study
#19
Andrew N Meltzoff, Rey R Ramírez, Joni N Saby, Eric Larson, Samu Taulu, Peter J Marshall
There is growing interest concerning the ways in which the human body, both one's own and that of others, is represented in the developing human brain. In two experiments with 7-month-old infants, we employed advances in infant magnetoencephalography (MEG) brain imaging to address novel questions concerning body representations in early development. Experiment 1 evaluated the spatiotemporal organization of infants' brain responses to being touched. A punctate touch to infants' hands and feet produced significant activation in the hand and foot areas of contralateral primary somatosensory cortex as well as in other parietal and frontal areas...
January 14, 2018: Developmental Science
https://www.readbyqxmd.com/read/29332138/pathophysiology-of-eosinophilic-esophagitis
#20
REVIEW
Benjamin P Davis
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus associated with an atopic predisposition which appears to be increasing in prevalence over the last few decades. Symptoms stem from fibrosis, swelling, and smooth muscle dysfunction. In the past two decades, the etiology of EoE has been and is continuing to be revealed. This review provides an overview of the effects of genetics, environment, and immune function including discussions that touch on microbiome, the role of diet, food allergy, and aeroallergy...
January 13, 2018: Clinical Reviews in Allergy & Immunology
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