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https://www.readbyqxmd.com/read/28319714/occupational-exposure-of-firefighters-to-polycyclic-aromatic-hydrocarbons-in-non-fire-work-environments
#1
Marta Oliveira, Klara Slezakova, Adília Fernandes, João Paulo Teixeira, Cristina Delerue-Matos, Maria do Carmo Pereira, Simone Morais
This work aims to characterize personal exposure of firefighters to polycyclic aromatic hydrocarbons (PAHs) in non-fire work environments (fire stations), and assesses the respective risks. Eighteen PAHs (16 considered by USEPA as priority pollutants, dibenzo[a,l]pyrene and benzo[j]fluoranthene) were monitored in breathing zones of workers at five Portuguese fire stations during a normal shift. The obtained levels of PAHs fulfilled all existent occupational exposure limits as well as air quality guidelines with total concentrations (ΣPAHs) in range of 46...
March 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28315689/in-silico-prediction-of-hpxr-activators-using-structure-based-pharmacophore-modeling
#2
Nao Torimoto-Katori, Ruili Huang, Harutoshi Kato, Rikiya Ohashi, Menghang Xia
The activation of pregnane X receptor (PXR), a member of the nuclear receptor superfamily, can mediate potential drug-drug interactions by regulating the expression of several drug- mediated enzymes and transporters, resulting in reduced therapeutic efficacy or increased toxicity by producing reactive metabolites. Therefore, in the early stage of drug development, it is important to predict these risks using an in silico approach. We constructed a human PXR (hPXR) pharmacophore model based on known structural information of compounds that activate PXR...
March 15, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28314229/how-did-the-good-school-toolkit-reduce-the-risk-of-past-week-physical-violence-from-teachers-to-students-qualitative-findings-on-pathways-of-change-in-schools-in-luwero-uganda
#3
N Kyegombe, S Namakula, J Mulindwa, J Lwanyaaga, D Naker, S Namy, J Nakuti, J Parkes, L Knight, E Walakira, K M Devries
Violence against children is a serious violation of children's rights with significant impacts on current and future health and well-being. The Good School Toolkit (GST) is designed to prevent violence against children in primary schools through changing schools' operational cultures. Conducted in the Luwero District in Uganda between 2012 and 2014, findings from previous research indicate that the Toolkit reduced the odds of past week physical violence from school staff (OR = 0.40, 95%CI 0.26-0.64, p < 0...
March 7, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28283012/-evaluation-of-mascia-brunelli-rapid-antigen-test-in-the-diagnosis-of-group-a-streptococcal-pharyngitis
#4
Ayşe Barış, Nur Anlıaçık, Mehmet Emin Bulut, Rıdvan Deniz, Elif Yücel, Elif Aktaş
Pharyngitis in most cases is due to viral microorganisms however drug therapy without the detection of etiological agent leads to unnecessary use of antibiotics. On the other hand, when the etiologic agent is group A beta-hemolytic streptococci (GAS) it is important to identify the etiologic agent rapidly which will guide the treatment with appropriate antibiotics. The use of highly sensitive rapid tests will contribute significantly to early diagnosis and appropriate therapy. The aim of this study is to evaluate the efficacy of Mascia Brunelli rapid antigen test for the detection of GAS in throat swab samples...
January 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28282087/-media-narrative-and-scientific-research
#5
María López Geist
The transmission of the scientific knowledge poses the question of the diversity of academic publications and stakeholders. Emphasis is placed on the relationship between scientific researchers and science journalists, and some issues that both handle with legitimate but different criteria are discussed. The complexity of the narrative in the discourse of science is evidenced when uncertainty and controversy take place. Some well-known bogus scientific stories in the media, such as Andrew Wakefield, Hwang Woo Suk and John Bohannon illustrate the role of the media and the factors of power in the social construction of knowledge...
July 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28280075/improving-reconciliation-following-medical-injury-a-qualitative-study-of-responses-to-patient-safety-incidents-in-new-zealand
#6
Jennifer Moore, Michelle M Mello
BACKGROUND: Despite the investment in exploring patient-centred alternatives to medical malpractice in New Zealand (NZ), the UK and the USA, patients' experiences with these processes are not well understood. We sought to explore factors that facilitate and impede reconciliation following patient safety incidents and identify recommendations for strengthening institution-led alternatives to malpractice litigation. METHODS: We conducted semistructured interviews with 62 patients injured by healthcare in NZ, administrators of 12 public hospitals, 5 lawyers specialising in Accident Compensation Corporation (ACC) claims and 3 ACC staff...
March 9, 2017: BMJ Quality & Safety
https://www.readbyqxmd.com/read/28262284/flow-mixing-during-peripheral-veno-arterial-extra-corporeal-membrane-oxygenation-a-simulation-study
#7
M C Stevens, F M Callaghan, P Forrest, P G Bannon, S M Grieve
Peripheral veno-arterial extra-corporeal membrane oxygenation (ECMO) is an artificial circulation that supports patients with severe cardiac and respiratory failure. Differential hypoxia during ECMO support has been reported, and it has been suggested that it is due to the mixing of well-perfused retrograde ECMO flow and poorly-perfused antegrade left ventricle (LV) flow in the aorta. This study aims to quantify the relationship between ECMO support level and location of the mixing zone (MZ) of the ECMO and LV flows...
February 21, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28258628/intracorporeal-anastomoses-in-emergency-laparoscopic-colorectal-surgery-from-a-series-of-59-cases-where-and-how-to-do-it-a-technical-note
#8
Salomone Di Saverio, Arianna Birindelli, Matteo Mandrioli, Mauro Podda, Gian Andrea Binda
BACKGROUND: Laparoscopy offers the benefits of minimally invasive surgery and faster recovery. Acute surgical patients may potentially benefit from the greatest advantages of emergency laparoscopy, even more clinically relevant in acute rather than elective patients. Fashioning a laparoscopic intra-corporeal anastomosis (ICA) after emergent colorectal resection, whenever technically feasible and non-contraindicated for the patients' general and hemodynamic condition, represents the most challenging technical skill to be learned...
March 4, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28243461/days-out-of-role-due-to-common-physical-and-mental-conditions-in-portugal-results-from-the-who-world-mental-health-survey
#9
Graça Cardoso, Miguel Xavier, Gemma Vilagut, Maria Petukhova, Jordi Alonso, Ronald C Kessler, José Miguel Caldas-de-Almeida
BACKGROUND: One important aspect of the societal burden of mental disorders is the extent to which these problems cause disability. AIMS: To assess days out of role associated with commonly occurring mental disorders in comparison with physical disorders in Portugal. METHOD: National cross-sectional survey, with home interviews carried out with 3849 adult (aged 18+) respondents (57.3% response rate). RESULTS: Twelve-month prevalence for any mental disorder was 21...
January 2017: BJPsych Open
https://www.readbyqxmd.com/read/28239459/effects-of-individual-household-and-community-characteristics-on-child-nutritional-status-in-the-slums-of-urban-bangladesh
#10
Karar Zunaid Ahsan, Shams El Arifeen, Md Abdullah Al-Mamun, Shusmita H Khan, Nitai Chakraborty
BACKGROUND: Bangladesh urban population is expected to overtake rural population by 2040, and a significant part of the increase will be in slums. Wide disparities between urban slums and the rest of the country can potentially push country indicators off track unless the specific health and nutrition needs of the expanding slum communities are addressed. The study aims at describing the individual, household and community determinants of undernutrition status among children living in major urban strata, viz...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28224766/thromboelastographic-evaluation-of-coagulation-in-patients-with-liver-disease
#11
Kyung Hwa Shin, In Suk Kim, Hyun Ji Lee, Hyung Hoi Kim, Chulhun L Chang, Young Mi Hong, Ki Tae Yoon, Mong Cho
BACKGROUND: The aims of this study were to investigate the parameters of thromboelastography (TEG) for evaluating coagulopathy and to reveal an association with disease severity and/or transfusion requirement in patients with chronic liver disease (CLD) in a clinical laboratory setting. METHODS: We enrolled two groups of adult patients with cirrhotic (N=123) and non-cirrhotic liver disease (N=52), as well as 84 healthy controls. Reaction time (R), kinetic time (K), α-angle (α), maximal amplitude (MA), and coagulation index (CI) were measured with kaolin-activated citrated blood with the TEG 5000 system (Haemonetics Corporation, USA)...
May 2017: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/28222235/visual-appearance-of-a-virtual-upper-limb-modulates-the-temperature-of-the-real-hand-a-thermal-imaging-study-in-immersive-virtual-reality
#12
G Tieri, A Gioia, M Scandola, E F Pavone, S M Aglioti
To explore the link between Sense of Embodiment (SoE) over a virtual hand and physiological regulation of skin temperature, twenty-four healthy participants were immersed in virtual reality through a Head Mounted Display and had their real limb temperature recorded by means of a high-sensitivity infrared camera. Participants observed a virtual right upper limb (appearing either normally, or with the hand detached from the forearm) or limb-shaped non-corporeal control objects (continuous or discontinuous wooden blocks) from a first-person perspective...
February 21, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28220682/the-treadmill-of-production-and-the-positional-economy-of-consumption
#13
Dean Curran
The theory of the treadmill of production highlights how the constant search for economic growth leads to advanced economies being stuck on a "treadmill," where their well-being is not improved by economic growth, yet the impacts of this pursuit of growth causes massive, unsustainable environmental damages. In interrogating the specific driving force that keeps the irrational system of the treadmill so powerfully in place, the theory of the treadmill of production focuses on how those who control the production process, corporations, are the primary agents driving the treadmill, while also highlighting how the state and workers generally continue to provide support for the treadmill's continued reproduction...
February 2017: Canadian Review of Sociology, Revue Canadienne de Sociologie
https://www.readbyqxmd.com/read/28217534/assessment-of-facial-golden-proportions-among-central-indian-population
#14
Rathore Saurabh, Bolya Piyush, Bhatt Sourabh, Ojha Preeti, Rutvik Trivedi, Pradeep Vishnoi
AIM: This study aimed to identify and establish the facial and smile proportions in young adults and to compare the results with ideal or divine proportions, compare the proportions of males and females included in our study population and compare them with those established for Caucasian and Japanese populations. MATERIALS AND METHODS: Two hundred participants (164 females, 36 males) with Angle's class I malocclusion (M.O). and well-balanced faces were selected and photographed in the frontal repose position...
December 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28217447/aging-related-erectile-dysfunction-potential-mechanism-to-halt-or-delay-its-onset
#15
REVIEW
Monica G Ferrini, Nestor F Gonzalez-Cadavid, Jacob Rajfer
Erectile dysfunction (ED) will visit every man at some time in his life. The age at when that knock on the door is heard is totally dependent on one's genetics as well as other extrinsic factors. Unlike guests who come for a visit and then leave, once ED shows up it tends to hang around forever. To add insult to injury, the longer ED hangs around, the worse it will get. It is estimated that by the time a man is in his 40's, he has about a 40% chance of having some form of ED and this prevalence increases about 10% per decade thereafter...
February 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28167709/tracking-the-changing-landscape-of-corporate-wellness-companies
#16
Jean Abraham, Katie M White
The corporate wellness industry is diversifying and now includes legacy wellness companies, divisions of health plans or delivery systems, and new technology-focused solution enterprises. We conducted in-depth interviews with leaders in the industry to understand the changes in its supply side, the drivers of these changes, future trends, and their implications for employers and policy makers. Three key trends emerged from the interviews: The industry is expanding and becoming increasingly diverse and competitive; wellness companies are redefining their business models to promote a culture of health; and the value proposition of employee wellness programs is shifting from a return on investment to a new idea: value on investment...
February 1, 2017: Health Affairs
https://www.readbyqxmd.com/read/28166435/adverse-events-during-inter-hospital-transports-on-extracorporeal-membrane-oxygenation
#17
Anders Ericsson, Björn Frenckner, L Mikael Broman
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) may be a lifesaving rescue therapy in refractory, severe respiratory, and/or circulatory failure. To provide the best cost efficiency to the population served and patient outcome, ECMO therapy should be provided by specialized high volume ECMO centers. This requires dedicated transport teams to organize and perform these complex transports. Concerning adverse events and complications during these transfers, only a minimal amount of data has been published...
February 6, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28166124/association-between-employee-sleep-with-workplace-health-and-economic-outcomes
#18
Wayne N Burton, Chin-Yu Chen, Alyssa B Schultz, Xingquan Li
OBJECTIVE: Poor sleep can impact occupational functioning. The current study examines health risks, medical conditions, and workplace economic outcomes associated with self-reported hours of sleep among employees. METHODS: Employees of a global financial services corporation were categorized on the basis of their self-reported average hours of sleep. Differences in health care costs, productivity measures, health risks, and medical conditions were analyzed by hours of sleep while controlling for confounding variables...
February 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28165332/exhaled-breath-and-oral-cavity-vocs-as-potential-biomarkers-in-oral-cancer-patients
#19
Marcos Bouza, Jesus Gonzalez-Soto, Rosario Pereiro, Juan Carlos de Vicente, Alfredo Sanz-Medel
Corporal mechanisms attributed to cancer, such as oxidative stress or the action of cytochrome P450 enzymes, seem to be responsible of the generation of a variety of volatile organic compounds (VOCs) that could be used as non-invasive diagnosis biomarkers. The present work presents an attempt of using VOCs from exhaled breath and oral cavity air as biomarkers for oral squamous cell carcinoma (OSCC) patients. 52 breath samples were collected (3 L Tedlar bags) from 26 OSCC patients and 26 cancer-free controls...
February 6, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28164355/analysis-of-the-appropriateness-of-off-label-antipsychotic-use-for-mental-health-indications-in-a-veteran-population
#20
Jacob T Painter, Richard Owen, Kathy L Henderson, Mark S Bauer, Dinesh Mittal, Teresa J Hudson
STUDY OBJECTIVE: A substantial proportion of antipsychotic (AP) use in veterans is for nonapproved indications (i.e., off-label prescribing). Not all off-label use is necessarily detrimental to patients, however, and in certain situations, off-label prescribing could be considered justifiable. The objective of this study was to determine the extent to which off-label AP prescribing in a veteran population was potentially appropriate. DESIGN: Expert panel and retrospective analysis...
February 5, 2017: Pharmacotherapy
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