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https://www.readbyqxmd.com/read/28546066/v-neck-technique-a-novel-improvement-to-the-infra-pubic-placement-of-an-inflatable-penile-implant
#1
Bhavik B Shah, Adam S Baumgarten, Kevin Morgan, Jonathan A Beilan, Michael Bickell, Ricardo Munarriz, Justin Parker, Rafael Carrion
BACKGROUND: Infra-pubic placement of an inflatable penile prosthesis (IPP) has a well-known configuration deformity from contralateral tubing that crosses the corporal bodies, resulting in tubing visibility and irritation under the penile skin. AIM: To present a novel step to eliminate this tubing crossover deformity. METHODS: The V-neck technique was applied to five patients, two of whom underwent suprapubic fat pad excision with simultaneous infra-pubic IPP placement and three patients who underwent only infra-pubic IPP placement...
May 22, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28544569/maintenance-of-the-contractile-phenotype-in-corpus-cavernosum-smooth-muscle-cells-by-myocardin-gene-therapy-ameliorates-erectile-dysfunction-in-bilateral-cavernous-nerve-injury-rats
#2
H-B Zhang, Z-Q Wang, F-Z Chen, W Ding, W-B Liu, Z-R Chen, S-H He, A-Y Wei
The pathophysiology of erectile dysfunction post radical prostatectomy is not clearly clarified, and the low efficacy of traditional PDE5i treatment remains a major complaint in contemporary practice. This study aimed to demonstrate phenotypic modulation in bilateral cavernous nerve injury (BCNI) rats within 7 days, and subsequently validate gene therapy with Myocardin (Mycod) by maintaining a contractile phenotype in corpus cavernosum smooth muscle cells. Initially, 36 male rats were randomly divided into BCNI and negative control (NC) groups for histological and phenotypic molecular measurements at 3, 5, and 7 days...
May 23, 2017: Andrology
https://www.readbyqxmd.com/read/28538054/achieving-high-reliability-with-people-processes-and-technology
#3
Candice L Saunders, John A Brennan
High reliability as a corporate value in healthcare can be achieved by meeting the "Quadruple Aim" of improving population health, reducing per capita costs, enhancing the patient experience, and improving provider wellness. This drive starts with the board of trustees, CEO, and other senior leaders who ingrain high reliability throughout the organization. At WellStar Health System, the board developed an ambitious goal to become a top-decile health system in safety and quality metrics. To achieve this goal, WellStar has embarked on a journey toward high reliability and has committed to Lean management practices consistent with the Institute for Healthcare Improvement's definition of a high-reliability organization (HRO): one that is committed to the prevention of failure, early identification and mitigation of failure, and redesign of processes based on identifiable failures...
July 2017: Frontiers of Health Services Management
https://www.readbyqxmd.com/read/28522181/safety-and-efficacy-of-edaravone-in-well-defined-patients-with-amyotrophic-lateral-sclerosis-a-randomised-double-blind-placebo-controlled-trial
#4
(no author information available yet)
BACKGROUND: In a previous phase 3 study in patients with amyotrophic lateral sclerosis (ALS), edaravone did not show a significant difference in the Revised ALS Functional Rating Scale (ALSFRS-R) score compared with placebo. Post-hoc analysis of these data revealed that patients in an early stage with definite or probable diagnosis of ALS, defined by the revised El Escorial criteria, who met a select set of inclusion criteria showed a greater magnitude of effect than did the full study population...
May 15, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28521022/management-of-untreatable-ventricular-arrhythmias-during-pharmacologic-challenges-with-sodium-channel-blockers-for-suspected-brugada-syndrome
#5
Stefano Poli, Mauro Toniolo, Massimo Maiani, Davide Zanuttini, Luca Rebellato, Igor Vendramin, Ermanno Dametto, Guglielmo Bernardi, Flavio Bassi, Carlo Napolitano, Ugolino Livi, Alessandro Proclemer
Pharmacologic challenge with sodium channel blockers is part of the diagnostic workout in patients with suspected Brugada syndrome. The test is overall considered safe but both ajmaline and flecainide detain well known pro-arrhythmic properties. Moreover, the treatment of patients with life-threatening arrhythmias during these diagnostic procedures is not well defined. Current consensus guidelines suggest to adopt cautious protocols interrupting the sodium channel blockers as soon as any ECG alteration appears...
May 17, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28511515/comparative-evaluation-of-antibacterial-and-adhesive-properties-of-chitosan-modified-glass-ionomer-cement-and-conventional-glass-ionomer-cement-an-in-vitro-study
#6
Arpan Debnath, Srivastava Bagepalli Kesavappa, Gyanendra Pratap Singh, Shruthi Eshwar, Vipin Jain, Madhuniranjan Swamy, Punith Shetty
INTRODUCTION: Recent studies have reported the incorporation of modifiers with conventional Glass Ionomer Cement (GIC) to enhance its antibacterial effect. One such modification being the addition of Chitosan (CH). However, these modifiers might affect the physical properties of the restorations. AIM: The aim of the present study was to investigate the effect of modifying the liquid phase of conventional GIC with 10% v/v CH on the antibacterial properties and adhesion to enamel in comparison to conventional GIC...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28506540/a-randomized-controlled-trial-of-an-intervention-program-to-brazilian-mothers-who-use-corporal-punishment
#7
Paolla Magioni Santini, Lucia C A Williams
This study evaluated a positive parenting program to Brazilian mothers who used corporal punishment with their children. The intervention was conducted in four agencies serving vulnerable children, and at a home replica laboratory at the University. Mothers who admitted using corporal punishment were randomly assigned between experimental (n=20) and control group (n=20). The program consisted of 12 individual sessions using one unit from Projeto Parceria (Partnership Project), with specific guidelines and materials on positive parenting, followed by observational sessions of mother-child interaction with live coaching and a video feedback session in the lab...
May 12, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28500596/measuring-blood-pressure-using-a-noninvasive-tail-cuff-method-in-mice
#8
Yu Wang, Sean E Thatcher, Lisa A Cassis
The renin angiotensin system (RAS) is well known for its role in regulating blood pressure (BP). An activated RAS contributes to elevated blood pressure and is evident in both human and animal models of hypertension. Drugs that target the classic vasoconstrictive arm of the RAS (angiotensin II/AT1 receptor signaling) are potent anti-hypertensive agents in clinical setting. However, the newly discovered angiotensin-converting enzyme 2 (ACE2)/angiotensin-(1-7)/Mas receptor axis added new vitality to the hypertension field...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28499737/endovascular-repair-as-a-bridge-to-open-repair-of-a-ruptured-descending-thoracic-aspergilus-aortitis
#9
Philippe Tresson, Arnaud Roussel, Pierre Mordant, Pierre Cerceau, Yves Castier, Quentin Pellenc
Invasive aspergillosis rarely involves the thoracic aorta, and is associated with a poor prognosis. A heart-transplanted 56-year old patient presented with invasive aspergillosis, primary aspergillus aortitis, and ruptured thoracic aorta pseudoaneurysm. Open surgery was not possible due to severe sepsis. A sequential surgical strategy was therefore decided, including emergency thoracic endovascular aneurysm repair, followed by antifungal treatment, and definitive open repair with explantation of the endograft and placement of a cryopreserved arterial allograft under extra-corporeal membrane oxygenator support...
May 9, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28495505/penile-fracture-following-a-fall-in-a-seven-year-old-male
#10
Bhalaajee Meenakshi-Sundaram, Caitlin T Coco, James R Furr, Marshall D Shaw, Dominic C Frimberger
We report a rare case of isolated penile fracture in a prepubescent male caused by an accidental fall. The patient presented with swelling and ecchymosis on the base of the penis and along the penile shaft. A flexible cystoscopy was performed which did not reveal any concomitant urethral injury. The penis was degloved and the corporal tear was closed with absorbable suture. Due to the location of the injury, ventral mobilization of the urethra was required. The pathophysiology of penile fracture as well as the diagnosis and management of this rare injury are discussed in this report...
May 8, 2017: Urology
https://www.readbyqxmd.com/read/28489162/endoscopic-sleeve-gastroplasty-for-obesity-treatment-two-years-of-experience
#11
Gontrand Lopez-Nava, M P Galvão, I Bautista-Castaño, J P Fernandez-Corbelle, M Trell, N Lopez
Background: Bariatric endoscopic techniques are minimally invasive and induce gastric volume reduction to treat obesity. Aim : To evaluate endoscopic sleeve gastroplasty (Apollo method) using a suturing method directed at the greater curvature, as well as the perioperative care, two year safety and weight loss. Method: Prospective single-center study over 154 patients (108 females) using the endoscopic sleeve gastroplasty procedure under general anesthesia with overnight inpatient observation...
January 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28486056/the-association-between-changes-in-employee-sleep-and-changes-in-workplace-health-and-economic-outcomes
#12
Chin-Yu Chen, Alyssa B Schultz, Xingquan Li, Wayne N Burton
Sleep disturbance is negatively associated with workplace productivity. This study sought to identify whether or not changes in sleep from 2012 to 2013 were associated with changes in health risks, medical conditions, or workplace economic outcomes. Employees of a Fortune 100 financial services corporation were categorized based on changes in self-reported hours of sleep from 2012 to 2013 and compared based on their health risk factors, medical conditions, health care costs, and productivity measures. Consistently poor sleepers had more health risks and medical conditions compared to consistently optimal sleepers...
May 9, 2017: Population Health Management
https://www.readbyqxmd.com/read/28481317/dogs-in-the-workplace-a-review-of-the-benefits-and-potential-challenges
#13
REVIEW
Anne M Foreman, Margaret K Glenn, B Jean Meade, Oliver Wirth
Pet dogs, therapy dogs, and service dogs can be seen in workplaces with increasing frequency. Although dogs may provide many benefits to employees and employers, their presence may introduce additional hazards and concerns to the work environment. Therefore, decisions to accept dogs in the workplace may include many considerations including the health, safety, and well-being of employees, legal and cultural sensitivities, and animal welfare. The present paper serves to introduce the issue of dogs in the workplace and outline the potential benefits and challenges to their presence...
May 8, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28472830/definitive-contraception-trends-in-a-ten-year-interval
#14
Cecília Maria Ventuzelo Marques, Magda Maria do Vale Pinto Magalhães, Maria João Leal da Silva Carvalho, Giselda Marisa Costa Carvalho, Francisco Augusto Falcão Santos Fonseca, Isabel Torgal
Objective To evaluate the trends in definitive contraception in a ten-year interval comprising the years 2002 and 2012. Method Retrospective analysis of the tubal sterilization performed in our service in 2002 and 2012, analyzing the demographic characteristics, personal history, previous contraceptive method, definite contraception technique, effectiveness and complications. Results Definitive contraception was performed in 112 women in 2002 (group 1) and in 60 women in 2012 (group 2). The groups were homogeneous regarding age, parity, educational level and personal history...
May 4, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28466202/four-wavelength-near-infrared-peripheral-oximetry-in-cardiac-surgery-patients-a-comparison-between-equanox-and-o3
#15
Arnaud Ferraris, Matthias Jacquet-Lagrèze, Jean-Luc Fellahi
Near-infrared spectroscopy (NIRS) is a continuous and noninvasive technology that measures regional tissue oxygen saturation (rSO2). A new 4-wavelength generation of NIRS monitors is now available. We aimed to compare peripheral somatic rSO2 values given by the 4-wavelength EQUANOX™ 7600 device (Nonin Medical Inc., Plymouth, Mn) and O3™ device (Masimo Corporation, Irvine, CA). Twenty adult patients scheduled for conventional elective cardiac surgery with cardiopulmonary bypass over a 4-month period were included after local Ethics Committee approval...
May 2, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28462792/implementation-of-a-reimbursed-medication-review-program-corporate-and-pharmacy-level-strategies
#16
Linda D MacKeigan, Nadine Ijaz, Elizabeth A Bojarski, Lisa Dolovich
BACKGROUND: In 2006, the Ontario drug plan greatly reduced community pharmacy reimbursement for generic drugs. In exchange, a fee-for-service medication review program was introduced to help patients better understand their medication therapy and ensure that medications were taken as prescribed. A qualitative study of community pharmacy implementation strategies was undertaken to inform a mixed methods evaluation of the program. PURPOSE: To describe strategies used by community pharmacies to implement a government-funded medication review service...
March 31, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28461443/recomposing-consumption-defining-necessities-for-sustainable-and-equitable-well-being
#17
Ian Gough
This paper focuses on consumption in the affluent world and the resulting level, composition and distribution of consumption-based emissions. It argues that public policy should foster the recomposition of consumption, while not disadvantaging poorer groups in the population. To combine these two imperatives entails making a distinction between goods and services that are necessary for a basic level of well-being, and those that are surplus to this requirement. The argument proceeds in six stages. First, the paper outlines a theory of universal need, as an alternative conception of well-being to consumer preference satisfaction...
June 13, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28457365/understanding-bone-damage-after-kidney-transplantation-a%C3%A2-retrospective-monocentric-cross-sectional-analysis
#18
M Gregorini, G Sileno, E F Pattonieri, V Corradetti, M Abelli, E Ticozzelli, L Scudeller, M A Grignano, P Esposito, L Bogliolo, A Giacomoni, T Rampino
BACKGROUND: Kidney transplantation (KT) immunosuppression may induce bone tissue damage with bone mineral density (BMD) loss increasing bone fractures risk. Steroid therapy is considered the major player, but others factors are still under review. PATIENTS AND METHODS: We designed an observational retrospective cohort study to evaluate bone damage after KT. The prevalence of osteopenia, osteoporosis, bone fractures, and the associated risk factors were investigated...
May 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28448815/spanking-and-subsequent-behavioral-problems-in-toddlers-a-propensity-score-matched-prospective-study-in-japan
#19
Sakurako Okuzono, Takeo Fujiwara, Tsuguhiko Kato, Ichiro Kawachi
Harsh or frequent spanking in early childhood is an established risk factor for later childhood behavioral problems as well as mental disorder in adulthood in Western societies. However, few studies have been conducted in Asian populations, where corporal punishment is relatively accepted. Moreover, the impacts of occasional spanking on subsequent behavioral problems remain uncertain. This study sought to investigate prospectively the association between the frequency of spanking of toddlers and later behavioral problems in Japanese children using national birth cohort data...
April 24, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28443022/evaluating-quality-of-decision-making-processes-in-medicines-development-regulatory-review-and-health-technology-assessment-a-systematic-review-of-the-literature
#20
REVIEW
Magdalena Bujar, Neil McAuslane, Stuart R Walker, Sam Salek
Introduction: Although pharmaceutical companies, regulatory authorities, and health technology assessment (HTA) agencies have been increasingly using decision-making frameworks, it is not certain whether these enable better quality decision making. This could be addressed by formally evaluating the quality of decision-making process within those organizations. The aim of this literature review was to identify current techniques (tools, questionnaires, surveys, and studies) for measuring the quality of the decision-making process across the three stakeholders...
2017: Frontiers in Pharmacology
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