Pradnya V Gadhave, Guruprasad V Sutar, Sachin J Sajane, Vivekkumar K Redasani, Kuntal Das, Dharani Prasad P, Saad Alobid, Ali Ibrahim Almoteer, Syed Imam Rabbani, Farhana Yasmin, Rafiulla Gilkaramenthi, Majidah Abdulrazaq AlAnazi, Haya Jameel Alshamrani, Syed Mohammed Basheeruddin Asdaq
BACKGROUND: Polycystic ovarian syndrome (PCOS) is one of the known causes of anovulatory fertility in the world. Previous research has linked oxidative stress could contribute to PCOS, and vanillic acid has shown antioxidant potential. Hence, the present study evaluated the effect of vanillic acid on letrozole-induced polycystic ovarian syndrome in female rats. MATERIALS AND METHODS: PCOS was induced in Wistar female rats with letrozole (1 mg/kg, orally) in carboxymethoxycellulose (1 % w/v), administered for 21 days...
February 2024: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society