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https://www.readbyqxmd.com/read/29793213/end-stage-renal-disease-models-in-the-americas-optimizing-resources-to-achieve-better-health-outcomes
#1
Ramiro E Gilardino, Eduardo González-Pier, Claudia Brabata
End-stage renal disease, the last and most severe stage of chronic kidney disease, represents a major and rising concern for countries in Latin America, driven in large part by aging populations and the near-epidemic rises in diabetes, obesity, and hypertension. This places a great clinical, economic, and social burden on the region's health systems. During the ISPOR 6th Latin America Conference held in Sao Paulo, Brazil, in September 2017, an educational forum debated on value-based decision making in the treatment of end-stage renal disease in Latin America...
May 21, 2018: Value in Health Regional Issues
https://www.readbyqxmd.com/read/29792877/coordinating-multi-protein-mismatch-repair-by-managing-diffusion-mechanics-on-the-dna
#2
REVIEW
Daehyung Kim, Richard Fishel, Jong-Bong Lee
DNA mismatch repair (MMR) corrects DNA base pairing errors that occur during DNA replication. MMR catalyzes strand-specific DNA degradation and resynthesis by dynamic molecular coordination of sequential downstream pathways. The temporal and mechanistic order of molecular events is essential to insure interactions in MMR that occur over long distances on the DNA. Biophysical real-time studies of highly conserved components on mismatched DNA have shed light on the mechanics of MMR. Single-molecule imaging has visualized stochastically coordinated MMR interactions that are based on thermal fluctuation-driven motions...
May 21, 2018: Journal of Molecular Biology
https://www.readbyqxmd.com/read/29792080/stakeholders-resistance-to-telemedicine-with-focus-on-physicians-utilizing-the-delphi-technique
#3
Woo Seok Choi, Joowoong Park, Jin Young Brian Choi, Jae-Suk Yang
Introduction Sufficient infrastructure for information and communications technology (ICT) and a well-established policy are necessary factors for smooth implementation of telemedicine. However, despite these necessary conditions being met, there are situations where telemedicine still fails to be accepted as a system due to the low receptivity of stakeholders. In this study, we analyse stakeholders' resistance to an organization's implementation of telemedicine. Focusing on the physicians' interests, we propose a strategy to minimize conflicts and improve acceptance...
January 1, 2018: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/29791823/doughnuts-and-discounts-changes-to-medicare-part-d-under-the-bipartisan-budget-act-of-2018
#4
Julie M Donohue, Haiden A Huskamp
The Medicare Prescription Drug Improvement and Modernization Act (MMA) of 2003 created a new Medicare benefit (Part D), a new insurance product (prescription-drug–only plans), and a new market. Fifteen years later, Part D is widely regarded as a success, providing drug coverage to 42.5 million..
May 24, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29791721/persistence-of-treatment-with-biologics-for-patients-with-psoriasis-a-real-world-analysis-of-16-545-biologic-na%C3%A3-ve-patients-from-the-french-national-health-insurance-database-sniiram
#5
E Sbidian, M Mezzarobba, A Weill, J Coste, J Rudant
BACKGROUND: Long-term clinical effectiveness of biologics in psoriasis is needed. OBJECTIVES: We aimed to assess the long-term persistence of biologics used to treat psoriasis in a real-life setting. METHODS: All adults with psoriasis having been registered in the French national health insurance database (SNIIRAM) between 2008 and 2016 were eligible for inclusion. Psoriasis was defined as the fulfilment of at least two prescriptions for topical formulations of vitamin D derivative within a two-year period...
May 23, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29791678/utilization-of-basic-health-units-of-fhs-according-to-private-health-insurance
#6
Leonardo Ferreira Fontenelle, Maria Beatriz Junqueira de Camargo, Andréa Dâmaso Bertoldi, Helen Gonçalves, Ethel Leonor Noia Maciel, Aluísio J D Barros
OBJECTIVE To describe the utilization of basic health units according to coverage by discount card or private health insurance. METHODS Household survey in the area covered by Family Health Strategy in Pelotas, state of Rio Grande do Sul, Brazil, from December 2007 to February 2008, with persons of all age groups. The frequency of (medical or non-medical) healthcare seeking at the basic health units in the last six months and the prevalence of basic health unit utilization for the last medical consultation (in case it had been performed up to six months before, for a non-routine reason) were analyzed by Poisson regression adjusted for the sampling design...
2018: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29791456/multi-species-suppression-of-herbivores-through-consumptive-and-non-consumptive-effects
#7
Kathryn S Ingerslew, Deborah L Finke
Most studies investigating the importance of non-consumptive interactions for herbivore suppression focus on pairwise interactions between one predator and one prey, ignoring any community context. Further, the potential for non-consumptive interactions to arise between herbivores and non-enemy organisms is commonly overlooked. We investigated the relative contributions of consumptive and non-consumptive effects to aphid suppression by a wasp assemblage containing both enemies and non-enemies. We examined the suppression of two aphid species with different defensive strategies, pea aphids (Acyrthosiphon pisum), which drop from their host plant to the ground, and green peach aphids (Myzus persicae), which remain on the plant and merely walk away...
2018: PloS One
https://www.readbyqxmd.com/read/29791255/the-calorie-labeling-saga-federal-preemption-and-delayed-implementation-of-public-health-law
#8
Jason P Block
Passing the 2010 Affordable Care Act (ACA) was a landmark event in health care policy. The ACA’s scope also went beyond health care. Included among myriad health insurance reforms and coverage expansions was Section 4205, a federal requirement for food-establishment chains with 20 or more locations..
May 23, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29790951/internet-use-and-preventive-health-behaviors-among-couples-in-later-life-evidence-from-the-health-and-retirement-study
#9
Sangbo Nam, Sae Hwang Han, Megan Gilligan
Background and Objectives: The aim of this study was to examine the link between internet use and preventive health behaviors. We focused on couples to examine whether there were cross-partner associations between internet use and preventive health behaviors. Research Design and Methods: The data for this study came from the 2010 and 2012 waves of the Health and Retirement Study and the sample consisted of 5,143 pairs of coupled-individuals. Preventive health behaviors included cancer screenings (mammogram and prostate tests), cholesterol tests, and flu shots...
May 22, 2018: Gerontologist
https://www.readbyqxmd.com/read/29790925/effectiveness-of-13-valent-pneumococcal-conjugate-vaccine-against-hospitalization-for-community-acquired-pneumonia-in-older-us-adults-a-test-negative-design
#10
John M McLaughlin, Qin Jiang, Raul E Isturiz, Heather L Sings, David L Swerdlow, Bradford D Gessner, Ruth M Carrico, Paula Peyrani, Timothy L Wiemken, William A Mattingly, Julio A Ramirez, Luis Jodar
Background: Following universal recommendation for use of 13-valent pneumococcal conjugate vaccine (PCV13) in US adults aged ≥65 years in September 2014, we conducted the first real-world evaluation of PCV13 vaccine effectiveness (VE) against hospitalized vaccine-type community-acquired pneumonia (CAP) in this population. Methods: Using a test-negative design, we identified cases and controls from a population-based surveillance study of adults in Louisville, Kentucky, who were hospitalized with CAP...
May 21, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29790923/missed-opportunities-to-prescribe-preexposure-prophylaxis-in-south-carolina-2013-2016
#11
Dawn K Smith, Man-Huei Chang, Wayne A Duffus, Stella Okoye, Sharon Weissman
Introduction: Expanding use of preexposure prophylaxis (PrEP) in ways that address current racial/ethnic disparities is an important HIV prevention goal. We investigated missed opportunities to provide PrEP during healthcare visits occurring prior to HIV infection. Methods: This retrospective cohort study linked South Carolina HIV case surveillance data to 3 statewide healthcare databases. Characteristics of patients, health care visits and providers, sexually transmitted diseases (STD), and other diagnoses, were assessed for medical encounters occurring before an initial HIV diagnosis...
May 22, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29790595/monetary-and-nonmonetary-household-consumption-of-health-services-and-the-role-of-insurance-benefits-an-analysis-of-the-mexico-s-national-household-income-and-expenditure-survey
#12
Edson Serván-Mori, Veronika J Wirtz
OBJECTIVES: To study the monetary and nonmonetary consumption of healthcare services at household level in Mexico and the magnitude of the contribution of public programs. METHODS: By using the National Household Income and Expenditure Survey 2012, we performed a cross-sectional and observational analysis of actual household consumption of health services by insurance type (no insurance, social security, Seguro Popular (SP)). Household consumption was divided into 2 categories: consumption related to "monetary" expenditure in health care and "nonmonetary" consumption in health care by the household...
May 23, 2018: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/29790265/lipid-lowering-medication-use-is-associated-with-decreased-risk-of-diabetic-retinopathy-and-its-treatments-in-patients-with-type-2-diabetes-a-real-world-observational-analysis-of-a-health-claims-database
#13
Ryo Kawasaki, Tsuneo Konta, Kohji Nishida
AIMS: Fenofibrate and statins reduced the risk of diabetic retinopathy (DR) related treatment in clinical trials. We aimed to determine whether lipid-lowering medication use reduce the risk of DR and its treatments in patients with type 2 diabetes using a real-world health claims database. METHODS: This was an observational analysis using a nation-wide health claims database of the Japan Medical Data Center (JMDC). Type 2 diabetes was defined by the ICD-10 codes with glucose-lowering medication use...
May 22, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29790166/physical-therapy-as-the-first-point-of-care-to-treat-low-back-pain-an-instrumental-variables-approach-to-estimate-impact-on-opioid-prescription-health-care-utilization-and-costs
#14
Bianca K Frogner, Kenneth Harwood, C Holly A Andrilla, Malaika Schwartz, Jesse M Pines
OBJECTIVE: To compare differences in opioid prescription, health care utilization, and costs among patients with low back pain (LBP) who saw a physical therapist (PT) at the first point of care, at any time during the episode or not at all. DATA SOURCES: Commercial health insurance claims data, 2009-2013. STUDY DESIGN: Retrospective analyses using two-stage residual inclusion instrumental variable models to estimate rates for opioid prescriptions, imaging services, emergency department visits, hospitalization, and health care costs...
May 23, 2018: Health Services Research
https://www.readbyqxmd.com/read/29790022/compliance-with-pregnancy-prevention-recommendations-for-isotretinoin-in-estonia-in-2012-2016
#15
Anneli Uusküla, Heti Pisarev, Katrin Kurvits, Ott Laius, Made Laanpere, Maia Uusküla
BACKGROUND: Isotretinoin is an effective treatment for severe acne; no alternative treatment has an equal therapeutic effect. The teratogenic effects of isotretinoin can be avoided, and numerous recommendations and regulations are in force to minimize the risk of pregnancy during treatment. OBJECTIVES: To describe isotretinoin prescription patterns for women aged 15-45 years, assess the concomitancy of isotretinoin and contraceptive use, and determine the rate of potential isotretinoin-exposed pregnancies in Estonia...
May 22, 2018: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/29789465/efficacy-safety-and-usability-of-remifentanil-as-premedication-for-insure-in-preterm-neonates
#16
Hadiyah Y Audil, Sara Tse, Chad Pezzano, Amy Mitchell-van Steele, Joaquim M B Pinheiro
Background : We previously reported a 67% extubation failure with INSURE (Intubation, Surfactant, Extubation) using morphine as analgosedative premedication. Remifentanil, a rapid- and short-acting narcotic, might be ideal for INSURE, but efficacy and safety data for this indication are limited. Objectives : To assess whether remifentanil premedication increases extubation success rates compared with morphine, and to evaluate remifentanil's safety and usability in a teaching hospital context. Methods : Retrospective review of remifentanil orders for premedication, at a large teaching hospital neonatal intensive care unit (NICU)...
May 22, 2018: Children
https://www.readbyqxmd.com/read/29789186/a-population-based-assessment-of-depression-and-anxiety-in-patients-with-brachial-plexus-injuries
#17
Sarah M Yannascoli, Dustin Stwalley, Mohammed J Saeed, Margaret A Olsen, Christopher J Dy
PURPOSE: Reactive depression and anxiety are common after major life changes such as brachial plexus injuries (BPI). The purpose of this study was to evaluate the incidence and risk factors for coded depression and coded anxiety among patients with BPI using a national database of commercial insurance claims. METHODS: We used the Truven MarketScan database from 2007 to 2013 to identify commercially insured patients aged 18 to 64 years who underwent BPI surgery. For comparison, a control group without BPI was frequency-matched 10:1 by age group, sex, number of provider visits, and length of insurance enrollment...
May 19, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29788687/trends-in-breast-reconstruction-implications-for-the-national-health-insurance-service
#18
Ki Yong Hong, Yoosung Son, Hak Chang, Ung Sik Jin
BACKGROUND: Breast reconstruction has become more common as mastectomy has become more frequent. In Korea, the National Health Insurance Service (NHIS) began covering breast reconstruction in April 2015. This study aimed to investigate trends in mastectomy and breast reconstruction over the past 10 years and to evaluate the impact of NHIS coverage on breast reconstruction. METHODS: Nationwide data regarding mastectomy and breast reconstruction were collected from the Korean Breast Cancer Society registry database...
May 2018: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/29788530/need-for-long-term-care-in-children-is-increasingly-caused-by-disorders-of-psychological-development-changes-in-the-care-causing-diagnoses-according-to-german-social-code-sgb-xi-between-2009-2014
#19
Julia Christiane Beck-Ripp, Holger Dressel
AIM OF THE STUDY: There is an ongoing discussion on the increasing number of children with mental and developmental disorders, with some even needing long-term care according to the German Social Code XI. This study was performed to identify the main diagnoses justifying such care in children and to analyse their prevalence over time. METHODS: The diagnoses justifying long-term care were evaluated using care assessments of Bavarian children and adolescents between 2009 to 2014 by the medical service of statutory health insurance...
May 22, 2018: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29788494/military-factors-associated-with-smoking-in-veterans
#20
Sara E Golden, Sujata Thakurta, Christopher G Slatore, Hyeyoung Woo, Donald R Sullivan
Introduction: Given the high prevalence of smoking among Veterans and the economic, social, and clinical implications, it is important to understand the factors that contribute to smoking in order to focus efforts to mitigate these factors and improve smoking cessation efforts among Veterans. The availability of research on smoking in Veterans compared with civilians is limited given the military-specific differences in their life course. We aimed to identify military-specific factors combined with sociodemographic factors for ever smoking and current smoking among Veterans to inform future interventions...
May 18, 2018: Military Medicine
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