Zhi-Yuan Liu, Qiong-Qiong Wang, Xian-Yong Pang, Xiao-Bi Huang, Gui-Ming Yang, Sheng Zhao
BACKGROUND: This study aims to thoroughly study the connection between congenital heart disease (CHD) and neurodevelopmental disorders (NDDs) through observational and Mendelian randomization (MR) designs. METHODS: This observational study uses data from the National Survey of Children's Health (2020-2021). Multivariable logistic regression and propensity score matching (PSM) were performed to analyze the association. PSM was used to minimize bias for covariates such as age, race, gender, maternal age, birth weight, concussion or brain injury, preterm birth, cerebral palsy, Down syndrome, and other inherited conditions...
April 8, 2024: Italian Journal of Pediatrics