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staph lugdunensis

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https://www.readbyqxmd.com/read/29614037/new-parameters-to-quantitatively-express-the-invasiveness-of-bacterial-strains-from-implant-related-orthopaedic-infections-into-osteoblast-cells
#1
Davide Campoccia, Lucio Montanaro, Stefano Ravaioli, Ilaria Cangini, Francesca Testoni, Livia Visai, Carla Renata Arciola
Complete eradication of bacterial infections is often a challenging task, especially in presence of prosthetic devices. Invasion of non-phagocytic host cells appears to be a critical mechanism of microbial persistence in host tissues. Hidden within host cells, bacteria elude host defences and antibiotic treatments that are intracellularly inactive. The intracellular invasiveness of bacteria is generally measured by conventional gentamicin protection assays. The efficiency of invasion, however, markedly differs across bacterial species and adjustments to the titre of the microbial inocula used in the assays are often needed to enumerate intracellular bacteria...
April 3, 2018: Materials
https://www.readbyqxmd.com/read/29559491/common-variable-immunodeficiency-presenting-in-a-man-with-recurrent-pneumonia-caused-by-staphylococcus-lugdunensis
#2
Nkechi Chiugo Mbaebie, Sylvia Vania Alarcon Velasco, Jason Touhey
Common variable immunodeficiency (CVID) refers to a group of disorders where differentiation and maturation of B cells into plasma cells are affected, leading to decreased or defective immunoglobulin production and subsequent immunodeficiency. Symptoms may present at any age between 5 and 72 years, although more severe forms often manifest earlier in life. Milder forms may not be detected. We present an intriguing case of a 69-year-old man presenting with recurrent pneumonia caused by a rare organism Staphylococcus lugdunensis , eventually determined to be caused by CVID...
March 20, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29469751/staphylococcus-lugdunensis-cutaneous-infection-with-sporotrichoid-distribution
#3
Nicola Di Meo, Sara Trevisini, Cecilia Noal, Katiuscia Nan, Giusto Trevisan
We report the occurrence of Staphylococcus lugdunensis cutaneous infection with sporotrichoid distribution of the left lower limb of a 60-year-old man. Recent studies have confirmed that Staphylococcus lugdunensis is a significant pathogen in causing skin and soft tissue infections that usually manifest in abscesses, surgical wound infections, and cellulitis. It used to be considered a skin commensal bacteria, but if unrecognized it can lead to  fulminant endocarditis, meningitis, skin abscesses, peritonitis, and spondylodiscitis...
August 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29468213/acute-onset-endophthalmitis-caused-by-staphylococcus-lugdunensis
#4
Robert B Garoon, Darlene Miller, Harry W Flynn
Purpose: To report a series of patients with acute-onset bacterial endophthalmitis caused by culture proven Staphylococcus lugdunensis , and to characterize clinical outcomes and microbiologic susceptibilities of this organism. Observations: The study included six eyes of 6 patients. The etiologies included cataract surgery (3), open globe injury (2), and intravitreal injection (1). Isolates of S. lugdunensis demonstrated sensitivity to vancomycin in all cases reported...
March 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29407401/antibiotic-susceptibility-of-methicillin-resistant-staphylococci-mrs-of-food-origin-a-comparison-of-agar-disc-diffusion-method-and-a-commercially-available-miniaturized-test
#5
Laura Buzón-Durán, Rosa Capita, Carlos Alonso-Calleja
Methicillin-resistant staphylococci (MRS) are a major concern to public and animal health. Thirty MRS (Staphylococcus aureus, S. cohnii, S. epidermidis, S. haemolyticus, S. hominis, S. lentus, S. lugdunensis, S. sciuri, and S. xylosus) isolates from meat and poultry preparations were tested for antimicrobial susceptibility to 11 antimicrobials (belonging to seven different categories) of clinical significance using both the standard agar disc diffusion method and a commercially available miniaturized system (Sensi Test Gram-positive)...
June 2018: Food Microbiology
https://www.readbyqxmd.com/read/29325360/-update-on-staphylococcus-lugdunensis-infective-endocarditis
#6
(no author information available yet)
No abstract text is available yet for this article.
December 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29187565/evaluation-of-oxacillin-and-cefoxitin-disk-diffusion-and-mic-breakpoints-established-by-the-clinical-and-laboratory-standards-institute-for-detection-of-meca-mediated-oxacillin-resistance-in-staphylococcus-schleiferi
#7
H K Huse, S A Miller, S Chandrasekaran, J A Hindler, S D Lawhon, D A Bemis, L F Westblade, R M Humphries
Staphylococcus schleiferi is a beta-hemolytic, coagulase-variable colonizer of small animals that can cause opportunistic infections in humans. In veterinary isolates, the rate of mecA -mediated oxacillin resistance is significant, with reported resistance rates of >39%. The goal of this study was to evaluate oxacillin and cefoxitin disk diffusion (DD) and MIC breakpoints for detection of mecA -mediated oxacillin resistance in 52 human and 38 veterinary isolates of S. schleiferi Isolates were tested on multiple brands of commercial media and according to Clinical and Laboratory Standards Institute (CLSI) methods...
February 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29063699/characterization-of-aicar-transformylase-imp-cyclohydrolase-atic-from-staphylococcus-lugdunensis
#8
Preeti Verma, Bibekananda Kar, Ritu Varshney, Partha Roy, Ashwani K Sharma
The 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/inosine monophosphate (IMP) cyclohydrolase (ATIC) catalyzes final two steps of purine nucleotide de novo biosynthetic pathway. This study reports the characterization of ATIC from Staphylococcus lugdunensis (SlugATIC). Apart from kinetic analysis and a detailed biophysical characterization of SlugATIC, the role of ATIC in cell proliferation has been demonstrated for the first time. The purified recombinant SlugATIC and its truncated domains exist mainly in dimeric form was revealed in gel-filtration and glutaraldehyde cross-linking studies...
December 2017: FEBS Journal
https://www.readbyqxmd.com/read/29035784/concentrations-of-staphylococcus-species-in-indoor-air-as-associated-with-other-bacteria-season-relative-humidity-air-change-rate-and-s-aureus-positive-occupants
#9
Anne Mette Madsen, Saloomeh Moslehi-Jenabian, Md Zohorul Islam, Mika Frankel, Michal Spilak, Margit W Frederiksen
The aim of this study was to obtain knowledge about concentrations of Staphylococcus aureus, MRSA (methicillin-resistant S. aureus), and other Staphylococcus species in indoor air in Greater Copenhagen and about factors affecting the concentrations. The effects of season, temperature, relative humidity, air change rate (ACR), other bacterial genera, area per occupant, and presence of S. aureus-positive occupants were studied. In samples from 67 living rooms, S. hominis, S. warneri, S. epidermidis, and S. capitis were found in 13-25%; S...
January 2018: Environmental Research
https://www.readbyqxmd.com/read/29022273/staphylococcus-lugdunensis-infections-of-the-skin-and-soft-tissue-a-case-series-and-review
#10
Lucas A Heldt Manica, Philip R Cohen
INTRODUCTION: Staphylococcus lugdunensis (S. lugdunensis) is a coagulase-negative, Gram-positive bacterium that can be isolated as a component of normal skin flora in humans. However, more recently, it has also been documented as a culprit in skin and soft tissue infections. We describe the clinical features of five individuals with S. lugdunensis-associated skin infections. We review the characteristics of other patients that were previously described with this organism as the causative agent of skin infection...
December 2017: Dermatology and Therapy
https://www.readbyqxmd.com/read/28962025/characterization-of-two-novel-variants-of-staphylococcal-cassette-chromosome-mec-elements-in-oxacillin-resistant-staphylococcus-lugdunensis
#11
Shih-Cheng Chang, Ming-Hsun Lee, Chun-Fu Yeh, Tsui-Ping Liu, Jung-Fu Lin, Cheng-Mao Ho, Jang-Jih Lu
Objectives: Staphylococcus lugdunensis, a species of CoNS, has become an important hospital pathogen because of increasing resistance to β-lactam antibiotics such as methicillin and oxacillin. Methicillin resistance is mainly due to the acquisition of the staphylococcal cassette chromosome (SCC) mec (SCCmec). Little is known about the structure of SCCmec in methicillin- or oxacillin-resistant CoNS. Methods: WGS was performed to determine the structure of SCCmec elements of two clinical S...
December 1, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28943172/staphylococcus-lugdunensis-small-colony-variant-conversion-resulting-in-chronic-prosthetic-joint-infection
#12
X Argemi, S Dahyot, J Lebeurre, Y Hansmann, C Ronde Oustau, G Prévost
No abstract text is available yet for this article.
November 2017: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/28937308/particularities-of-staphylococcus-lugdunensis-in-orthopaedic-infections
#13
Morad Mohamad, Ilker Uçkay, Didier Hannouche, Hermès Miozzari
No abstract text is available yet for this article.
September 22, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28906479/characterization-of-vb_saum-frusau02-a-twort-like-bacteriophage-isolated-from-a-therapeutic-phage-cocktail
#14
Katarzyna Leskinen, Henni Tuomala, Anu Wicklund, Jenni Horsma-Heikkinen, Pentti Kuusela, Mikael Skurnik, Saija Kiljunen
Staphylococcus aureus is a commensal and pathogenic bacterium that causes infections in humans and animals. It is a major cause of nosocomial infections worldwide. Due to increasing prevalence of multidrug resistance, alternative methods to eradicate the pathogen are necessary. In this respect, polyvalent staphylococcal myoviruses have been demonstrated to be excellent candidates for phage therapy. Here we present the characterization of the bacteriophage vB_SauM-fRuSau02 (fRuSau02) that was isolated from a commercial Staphylococcus bacteriophage cocktail produced by Microgen (Moscow, Russia)...
September 14, 2017: Viruses
https://www.readbyqxmd.com/read/28839395/staphylococcus-lugdunensis-and-trichophyton-tonsurans-infection-in-synthetic-hair-implants
#15
Pedro Colli, Antonia Fellas, Ralph M Trüeb
Synthetic hair implants are considered in alopecia when the patient requests an immediate result with minor surgery and with a poor donor area. However, the procedure has historically been marred by poor quality fiber and performance resulting in serious complications. Nevertheless, companies continue to market the procedure with the claim that previous problems have been sorted out. We report a case of inflammation in synthetic hair implants, in which microbiological studies revealed infection with Staphylococcus lugdunensis and Trichophyton tonsurans...
April 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28835477/is-staphylococcus-lugdunensis-significant-in-clinical-samples
#16
REVIEW
Xavier Argemi, Yves Hansmann, Philippe Riegel, Gilles Prévost
The implication of coagulase-negative staphylococci in human diseases is a major issue, particularly in hospital settings wherein these species often act as opportunistic pathogens. In addition, some coagulase-negative staphylococci such as S. lugdunensis have emerged as pathogenic bacteria, implicated in severe infections, particularly, osteoarticular infections, foreign-body-associated infections, bacteremia, and endocarditis. In vitro studies have shown the presence of several putative virulence factors such as adhesion factors, biofilm production, and proteolytic factors that might explain clinical manifestations...
November 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28751155/primary-lung-abscess-caused-by-staphylococcus-lugdunensis
#17
Deng-Wei Chou, Chao-Tai Lee
Staphylococcus lugdunensis, a strain of coagulase-negative staphylococci, is part of the normal flora of human skin but can cause multiple infections at various sites. This microorganism has emerged as a major human pathogen. However, no study has reported primary lung abscess caused by S. lugdunensis. A 54-year-old alcoholic man without relevant past medical history was admitted because of primary lung abscesses. Empirical amoxicillin/clavulanate therapy was initially administered; however, the patient had persistent pleuritic chest pain and fever...
July 24, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28747897/identification-of-emerging-human-mastitis-pathogens-by-maldi-tof-and-assessment-of-their-antibiotic-resistance-patterns
#18
María Marín, Rebeca Arroyo, Irene Espinosa-Martos, Leónides Fernández, Juan M Rodríguez
Lactational mastitis constitutes one of the main causes of undesired weaning, depriving the mother-infant pair from the benefits of breastfeeding; therefore, this condition should be considered a relevant public health issue. The role of specific microorganisms remains unclear since human milk cultures and antibiotic susceptibility testing (AST) are not routinely performed, despite the fact that this would be key to ensure an early and effective diagnosis and treatment. The objective of this study was to describe the culturable microbial diversity in 647 milk samples from breastfeeding women with clinical symptoms of mastitis by Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF) VITEK MS technology and to analyze the antimicrobial susceptibility profiles of a collection of isolates from these samples by the VITEK 2 AST system...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28717325/tetracycline-resistance-phenotypes-and-genotypes-of-coagulase-negative-staphylococcal-isolates-from-bubaline-mastitis-in-egypt
#19
K A Abd El-Razik, A A Arafa, R H Hedia, E S Ibrahim
AIM: This study was devoted to elucidate the tetracycline resistance of coagulase-negative staphylococci (CNS) derived from normal and subclinical mastitic (SCM) buffaloes' milk in Egypt. MATERIALS AND METHODS: A total of 81 milk samples from 46 normal buffalo milk samples and 35 SCM buffalo milk samples at private dairy farms of Egypt were used in this study. CNS were identified using phenotypic and molecular methods (polymerase chain reaction [PCR]). CNS isolates were tested for tetracycline resistance using routine methods and multiplex PCR targeting tetracycline (tet) resistance genes followed by sequencing of positive PCR products and phylogenetic analysis...
June 2017: Veterinary World
https://www.readbyqxmd.com/read/28702199/prevalence-of-methicillin-resistance-and-macrolide-lincosamide-streptogramin-b-resistance-in-staphylococcus-haemolyticus-among-clinical-strains-at-a-tertiary-care-hospital-in-thailand
#20
S Teeraputon, P Santanirand, T Wongchai, W Songjang, N Lapsomthob, D Jaikrasun, S Toonkaew, P Tophon
Staphylococcus spp. is a major cause of nosocomial infection and sepsis. However, increasing drug resistance is becoming a challenge to microbiologists. The purpose of this study was to identify and determine antimicrobial resistance phenotypes and drug resistance genes of clinical coagulase-negative staphylococci (CoNS) isolates at Mae Sot Hospital in Tak province, Thailand. A total of 229 CoNS isolates were collected from clinical specimens during two periods in 2014 and in 2015. Staphylococcus haemolyticus was the most prevalent species (37...
September 2017: New Microbes and New Infections
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