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Injury risk factors

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https://www.readbyqxmd.com/read/29793034/a-case-control-study-about-foetal-trauma-during-cesarean-delivery
#1
Enora Dolivet, Cécile Delesalle, Rémi Morello, Marie Blouet, Corinne Bronfen, Michel Dreyfus, Guillaume Benoist
OBJECTIVE: The caesarean section rate is gradually increasing in most countries. The frequency of occurrence of foetal injury per birth is estimated to 1%. The majority of these injuries presents a low functional impact, but remains responsible for a significant neonatal morbidity. Even though the foetal risk factors are well documented in cases of vaginal birth, they have not been accurately identified for cesarean section. The aim of this study is to identify the risk factors for neonatal fracture during caesarean section...
May 21, 2018: Journal of Gynecology Obstetrics and Human Reproduction
https://www.readbyqxmd.com/read/29792895/pharmacogenomics-of-drug-induced-liver-injury-dili-molecular-biology-to-clinical-applications
#2
REVIEW
Kalaiyarasi Kaliyaperumal, Jane I Grove, Robin M Delahay, William J H Griffiths, Adam Duckworth, Guruprasad P Aithal
A number of drug-specific and host-related factors contribute to the development of drug-induced liver injury (DILI). Investigations focused on genetic susceptibility to DILI have advanced our understanding of the pathogenesis of this rare, yet potentially life-threatening adverse reaction. Candidate gene studies involving well-characterized patients with DILI and drug-exposed controls have identified single nucleotide polymorphisms (SNPs) affecting the metabolism and clearance of specific drugs and hence, influencing individual's susceptibility to DILI...
May 21, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29792569/the-relationship-between-suicidal-responses-and-traumatic-brain-injury-and-severe-insomnia-in-active-duty-veteran-and-civilian-populations
#3
Kelly A Soberay, Jetta E Hanson, Megan Dwyer, E Ashby Plant, Peter M Gutierrez
OBJECTIVE: This study examined how a positive traumatic brain injury (TBI) screening and insomnia severity relates to suicidal outcomes across active duty, veteran, and civilian samples. METHODS: Data were used from 3,993 participants from 19 studies. We conducted a series of analyses by group to identify which significantly differed on the variables of interest. RESULTS: TBI and insomnia each had independent relationships with outcomes over and above the impact of the other factor...
May 24, 2018: Archives of Suicide Research: Official Journal of the International Academy for Suicide Research
https://www.readbyqxmd.com/read/29792528/dissociation-of-cerebrospinal-fluid-amyloid-%C3%AE-and-tau-levels-in-patients-with-prolonged-posttraumatic-disorders-of-consciousness
#4
Sergio Bagnato, Maria Andriolo, Cristina Boccagni, Antonino Sant'Angelo, Maria Enza D'Ippolito, Giuseppe Galardi
BACKGROUND: Traumatic brain injury (TBI) is a major risk factor for Alzheimer's disease (AD). Although the mechanisms that lead to AD after a TBI are unclear, we hypothesize that changes in amyloid-β (Aβ) metabolism and abnormal tau phosphorylation are reasonable candidates. OBJECTIVE: To investigate Aβ and tau dynamics in the chronic phase of TBI. METHODS: We evaluated Aβ1-42 , total tau (t-tau), and phosphorylated tau (p-tau) levels in the cerebrospinal fluid (CSF) of 15 patients who developed a prolonged disorder of consciousness after a severe TBI (mean time from TBI 271...
May 24, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29792105/risk-factors-for-groin-injury-and-symptoms-in-elite-level-soccer-players-a-cohort-study-in-the-dutch-professional-leagues
#5
Rob Langhout, Igor Tak, Anne-Marie van Beijsterveldt, Martijn Ricken, Adam Weir, Maarten Barendrecht, Gino Kerkhoffs, Janine Stubbe
Study Design Cohort study with prospective and retrospective elements. Background Groin injury and symptoms are common in soccer players. Their relationship with reduced hip range of motion (ROM) and previous injury is unclear. Objectives To conduct a retrospective assessment of associations between previous injury and pre-season hip ROM and pre-season prevalence of severe groin symptoms; and prospective identification of risk factors for within-season groin injury. Methods During 2015-2016, 190 players from 9 Dutch professional soccer clubs participated...
May 23, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29791977/no-association-between-rate-of-torque-development-and-onset-of-muscle-activity-with-increased-risk-of-hamstring-injury-in-elite-football
#6
Nicol van Dyk, Roald Bahr, Angus F Burnett, Evert Verhagen, Damien von Tiggelen, Erik Witvrouw
INTRODUCTION: Hamstring injuries remain a significant burden in sports that involve high speed running. In elite male football, hamstring injury has repeatedly been identified as the most common noncontact injury, representing 12% of all injuries. As the incidence remains high, investigations are aimed at better understanding how to improve prevention efforts. Intrinsic risk factors such as strength have been investigated extensively in a cohort of professional football players; however, other intrinsic measures of neuromuscular function have not been studied in this cohort...
May 23, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29791183/a-2-year-prospective-cohort-study-of-overuse-running-injuries-the-runners-and-injury-longitudinal-study-trails
#7
Stephen P Messier, David F Martin, Shannon L Mihalko, Edward Ip, Paul DeVita, D Wayne Cannon, Monica Love, Danielle Beringer, Santiago Saldana, Rebecca E Fellin, Joseph F Seay
BACKGROUND: The National Center for Injury Prevention and Control, noting flaws in previous running injury research, called for more rigorous prospective designs and comprehensive analyses to define the origin of running injuries. PURPOSE: To determine the risk factors that differentiate recreational runners who remain uninjured from those diagnosed with an overuse running injury during a 2-year observational period. STUDY DESIGN: Cohort study; Level of evidence, 2...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29791182/season-ending-shoulder-injuries-in-the-national-collegiate-athletic-association-data-from-the-ncaa-injury-surveillance-program-2009-2010-through-2013-2014
#8
Avi D Goodman, Steven F DeFroda, Joseph A Gil, Justin E Kleiner, Neill Y Li, Brett D Owens
BACKGROUND: Examination of the incidence of shoulder season-ending injury (SEI) in the collegiate athlete population is limited. PURPOSE: To determine the incidence of shoulder SEI in the National Collegiate Athletic Association (NCAA) and to investigate the risk factors for a shoulder injury ending an athlete's season. STUDY DESIGN: Descriptive epidemiology study. METHODS: All shoulder injuries from the NCAA Injury Surveillance Program database for the years 2009-2010 to 2013-2014 were extracted, and SEI status was noted...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29791174/-drug-and-herbal-hepatotoxicity-an-overview-of-clinical-classifications
#9
Mária Szántová, Jozef Sedlačko, Martina Jakabovičová
Drug induced liver injury (DILI) is often underdiagnosed disease with increasing incidence. In developed countries it belongs to the leading causes of acute liver failure. Risk groups are women and persons older than 60 years. The work summarizes the up to date information on diagnosis and mostly used classifications on DILI. It is quite often and serious complication of medicament therapy. DILI belongs to the most often cause of acute hepatic failure in the old age in developed countries. Diagnostic procedure includes medical history (time correlation with drug intake), clinical symptoms and blood tests...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29791065/risk-factors-of-valproic-acid-induced-hyperammonaemia-in-chinese-paediatric-patients-with-epilepsy
#10
Xu Zhu, Xinlin Li, Ti Zhang, Limei Zhao
The present study was aimed at identifying genetic and non-genetic risk factors for valproic acid (VPA)-induced hyperammonaemia in Chinese paediatric patients with epilepsy. A total of 210 epileptic patients, treated with VPA as monotherapy, were enrolled and classified into hyperammonaemia and control groups according to their blood ammonia level (cut-off value 50 μmol/L). Serum concentrations of VPA and its major metabolites were simultaneously determined by ultra-high performance liquid chromatography-tandem mass spectrometry...
May 23, 2018: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29789993/the-role-of-the-epithelial-to-mesenchymal-transition-emt-in-diseases-of-the-salivary-glands
#11
REVIEW
Margherita Sisto, Sabrina Lisi, Domenico Ribatti
The link between inflammatory microenvironment and cancer emerged in the last years as a decisive factor in the induction of the pathological epithelial-mesenchymal transition (EMT). The EMT induces changes of cell states converting the epithelial cells to mesenchymal cells when this program is fully executed and EMT has emerged as a central driver of tumor malignancy. Cellular pathways activated by chronic inflammation brought about by chronic infections, by immune-mediated diseases, or by dysregulated wound healing at sites of repetitive tissue injury, constitute risk factors or initial cell transformation and for cancer progression...
May 23, 2018: Histochemistry and Cell Biology
https://www.readbyqxmd.com/read/29789186/a-population-based-assessment-of-depression-and-anxiety-in-patients-with-brachial-plexus-injuries
#12
Sarah M Yannascoli, Dustin Stwalley, Mohammed J Saeed, Margaret A Olsen, Christopher J Dy
PURPOSE: Reactive depression and anxiety are common after major life changes such as brachial plexus injuries (BPI). The purpose of this study was to evaluate the incidence and risk factors for coded depression and coded anxiety among patients with BPI using a national database of commercial insurance claims. METHODS: We used the Truven MarketScan database from 2007 to 2013 to identify commercially insured patients aged 18 to 64 years who underwent BPI surgery. For comparison, a control group without BPI was frequency-matched 10:1 by age group, sex, number of provider visits, and length of insurance enrollment...
May 19, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29789136/penetrating-trauma-in-children-on-the-united-states-mexico-border-hispanic-ethnicity-is-not-a-risk-factor
#13
Loc-Uyen T Vo, Clark Anderson, Samantha Thomas, Hannah Vernia, Jarett K Howe, Alan H Tyroch, Tamara N Fitzgerald
INTRODUCTION: The United States-Mexico border is perceived as dangerous by the media and current political leaders. Hispanic ethnicity, low socioeconomic status, male gender and adolescent age have previously been identified as risk factors for penetrating trauma (PT). METHODS: A retrospective review of PT was performed in a border region. Children 0-17 years old, admitted to the region's only level I trauma center between 2001 and 2016 were included. Standardized morbidity ratio was used to compare observed to expected morbidity...
May 17, 2018: Injury
https://www.readbyqxmd.com/read/29789089/-gz-exposure-and-spinal-injury-induced-flight-duty-limitations
#14
Tuomas Honkanen, Roope Sovelius, Matti Mäntysaari, Heikki Kyröläinen, Janne Avela, Tuomo K Leino
BACKGROUND: The present study aimed to find out if possible differences in early military flight career +Gz exposure level could predict permanent flight duty limitations (FDL) due to spinal disorders during a pilot's career. METHODS: The study population consisted of 23 pilots flying with Gz limitation (max limitation ranging from +2 Gz to +5 Gz) due to spinal disorders and 50 experienced (+1000 flight hours) symptomless controls flying actively in operative missions in the Finnish Air Force...
June 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29788836/intracranial-hemorrhage-in-adults-on-ecmo
#15
Yiorgos Alexandros Cavayas, Lorenzo Del Sorbo, Eddy Fan
RATIONALE: Extracorporeal membrane oxygenation (ECMO) use has exploded over the last decade. However, it remains invasive and associated with significant complications, including tamponade, infection, thrombosis, gas embolism and bleeding. The most dreaded complication is intracranial hemorrhage (ICH). In this article, we review the literature on the incidence, diagnosis, risk factors, pathophysiology, prognosis, prevention and management of ICH in adults on ECMO. MAIN FINDINGS: We found a high incidence of ICH in the literature with a poor prognosis...
May 2018: Perfusion
https://www.readbyqxmd.com/read/29788820/injury-and-infection-in-dental-clinics-risk-factors-and-prevention
#16
Mustafa Al-Zoughool, Zaina Al-Shehri
Needlestick and sharp instrument injuries are common in dental practice and present the risk of direct exposure to blood-borne pathogens, including hepatitis B virus. This cross-sectional study was carried out to determine the risk factors of injury and infection in three types of dental clinic in Riyadh, Saudi Arabia. A total of 274 male and 241 female dentists completed a structured questionnaire on demographic factors, compliance with infection control practices, and past exposure to injury and infection hazards...
January 1, 2018: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/29788751/radiographic-analysis-of-the-correlation-between-ossification-of-the-nuchal-ligament-and-sagittal-alignment-and-segmental-stability-of-the-cervical-spine-in-patients-with-cervical-spondylotic-myelopathy
#17
Jinwei Ying, Honglin Teng, Yunfan Qian, Yingying Hu, Tianyong Wen, Dike Ruan, Minyu Zhu
Background Ossification of the nuchal ligament (ONL) caused by chronic injury to the nuchal ligament (NL) is very common in instability-related cervical disorders. Purpose To determine possible correlations between ONL, sagittal alignment, and segmental stability of the cervical spine. Material and Methods Seventy-three patients with cervical spondylotic myelopathy (CSM) and ONL (ONL group) and 118 patients with CSM only (control group) were recruited. Radiographic data included the characteristics of ONL, sagittal alignment and segmental stability, and ossification of the posterior longitudinal ligament (OPLL)...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29788153/aggregate-analysis-of-sentinel-events-as-a-strategic-tool-in-safety-management-can-contribute-to-the-improvement-of-healthcare-safety
#18
Angelo B Hooker, Anouk Etman, Matthijs Westra, Wouter J Van der Kam
Objective: To examine if clustering of root causes of sentinel events (SEs) can contribute to organisational improvement of healthcare and patient safety by providing insight into organisational risk factors, patterns and trends. Design: Retrospective, cross-sectional review of SEs from a hospital database reported to the Board of directors in 2016. Setting: A regional teaching hospital in the Netherlands. Intervention(s): Clustering of characteristics and variables of SEs to establish vulnerabilities and patterns of failure factors of the organisation...
May 19, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29788071/educating-australian-musicians-are-we-playing-it-safe
#19
Suzanne Wijsman, Bronwen J Ackermann
The effectiveness of health promotion through arts engagement, and the health benefits and social importance of music in particular, are becoming increasingly recognized. However, like sport, music-making is an athletic endeavour, one that often involves high physiological and psychological loadings on the bodies and minds of musicians. Research over the past 30 years has revealed alarming rates of injury among musicians, and has identified health risk factors associated with music performance faced by professional and student musicians...
May 17, 2018: Health Promotion International
https://www.readbyqxmd.com/read/29787864/the-neonatal-brain-in-critical-congenital-heart-disease-insights-and-future-directions
#20
REVIEW
Shabnam Peyvandi, Beatrice Latal, Steven P Miller, Patrick S McQuillen
Neurodevelopmental outcomes are impaired in survivors of critical congenital heart disease (CHD) in several developmental domains including motor, cognitive and sensory outcomes. These deficits can extend into the adolescent and early adulthood years. The cause of these neurodevelopmental impairments is multi-factorial and includes patient specific risk factors, cardiac anatomy and physiology as well as brain changes seen on MRI. Advances in imaging techniques have identified delayed brain development in the neonate with critical CHD as well as acquired brain injury...
May 19, 2018: NeuroImage
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