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https://www.readbyqxmd.com/read/28943834/cutaneous-lyme-borreliosis-guideline-of-the-german-dermatology-society
#1
Heidelore Hofmann, Volker Fingerle, Klaus-Peter Hunfeld, Hans-Iko Huppertz, Andreas Krause, Sebastian Rauer, Bernhard Ruf
This guideline of the German Dermatology Society primarily focuses on the diagnosis and treatment of cutaneous manifestations of Lyme borreliosis. It has received consensus from 22 German medical societies and 2 German patient organisations. It is the first part of an AWMF (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften e.V.) interdisciplinary guideline: "Lyme Borreliosis - Diagnosis and Treatment, development stage S3". The guideline is directed at physicians in private practices and clinics who treat Lyme borreliosis...
2017: German Medical Science: GMS E-journal
https://www.readbyqxmd.com/read/28906088/bullous-cutaneous-larva-migrans-case-series-and-review-of-atypical-clinical-presentations
#2
Stefano Veraldi, Ermira Çuka, Paolo Pontini, Fabrizio Vaira
Hookworm-related cutaneous larva migrans (HRCLM) is caused by the penetration and migration in the epidermis of larvae of Ancylostoma braziliense and Ancylostoma caninum. It is characterized by slightly raised and erythematous tracks, located especially on the feet. These tracks may be single or multiple, serpiginous or linear, ramified and intertwined, accompanied by pruritus. Atypical clinical presentations of HRCLM are currently more frequent than in the past. We present six patients with bullous HRCLM and discuss the possible pathogenetic factors...
October 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28794875/the-humtick-study-protocol-for-a-prospective-cohort-study-on-post-treatment-lyme-disease-syndrome-and-the-disease-and-cost-burden-of-lyme-borreliosis-in-belgium
#3
Laurence Geebelen, Tinne Lernout, Benoît Kabamba-Mukadi, Veroniek Saegeman, Hein Sprong, Steven Van Gucht, Philippe Beutels, Niko Speybroeck, Katrien Tersago
BACKGROUND: In Belgium, different routine surveillance systems are in place to follow-up Lyme borreliosis trends. However, accurate data on the disease and monetary burden for the different clinical manifestations are lacking. Despite recommended antibiotic treatment, a proportion of Lyme patients report persisting aspecific symptoms for six months or more (e.g. fatigue, widespread musculoskeletal pain, cognitive difficulties), a syndrome now named "post-treatment Lyme disease syndrome" (PTLDS)...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28754237/treatment-of-larva-migrans-syndrome-with-long-term-administration-of-albendazole
#4
Amy Hombu, Ayako Yoshida, Taisei Kikuchi, Eiji Nagayasu, Mika Kuroki, Haruhiko Maruyama
BACKGROUND: Larva migrans syndrome is a food-borne parasitic disease in humans, caused by accidental ingestion of eggs or larvae of ascarid nematodes, namely, Toxocara canis, Toxocara cati, or Ascaris suum, the roundworms commonly found in the intestines of dogs, cats and pigs respectively. When a patient is diagnosed as having larva migrans syndrome, oral-administration of albendazole is recommended, however, the regimen remains controversial worldwide. In Japan, the duration of albendazole administration is longer than those of European and North American countries...
July 14, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28705754/progression-of-lyme-disease-to-bell-s-palsy-despite-treatment-with-doxycycline
#5
Luis A Marcos, Zengmin Yan
No abstract text is available yet for this article.
September 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28624508/epidemiological-profile-of-cutaneous-larva-migrans-in-travelers-returning-to-france-between-2003-and-2015
#6
Doudou Sow, Ferelaha Soro, Emilie Javelle, Fabrice Simon, Philippe Parola, Philippe Gautret
BACKGROUND: Cutaneous larva migrans (CLM) is caused by the penetration and migration of canine or feline hookworm larvae into the skin, and frequently affects travelers from high-income countries returning from tropical and sub-tropical areas. Unfortunately, this pathology is neglected due to poor understanding among both physicians and travelers. This study describes the profile of cases reported in Marseille, France. PATIENTS AND METHODS: A retrospective study was performed in two specialized hospitals between 2003 and 2015...
June 15, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/28533930/early-onset-lyme-carditis-with-concurrent-disseminated-erythema-migrans
#7
Kinjan P Patel, Peter D Farjo, Joy J Juskowich, Ali Hama Amin, James D Mills
BACKGROUND: Lyme disease is an infection that is estimated to affect over 300,000 people in the United States annually. Typically, it presents with erythema migrans (EM), an annular rash at the site of tick attachment, within 3 to 30 days of inoculation. Untreated patients may progress to early disseminated disease. A further complication, Lyme carditis is rare but may occur several weeks later. It commonly manifests as a variable atrioventricular (AV) conduction block, with a high-grade AV block occurring in only 1% of untreated patients...
2017: American Journal of Cardiovascular Disease
https://www.readbyqxmd.com/read/28532428/practices-of-lyme-disease-diagnosis-and-treatment-by-general-practitioners-in-quebec-2008-2015
#8
Salima Gasmi, Nicholas H Ogden, Patrick A Leighton, Ariane Adam-Poupart, François Milord, L Robbin Lindsay, Sapha Barkati, Karine Thivierge
BACKGROUND: Lyme disease (LD), a multisystem infection caused by the spirochete Borrelia burgdorferi sensu stricto (B. burgdorferi), is the most reported vector-borne disease in North America, and by 2020, 80% of the population in central and eastern Canada could live in LD risk areas. Among the key factors for minimising the impact of LD are the accurate diagnosis and appropriate management of patients bitten by ticks. In this study, the practices of Quebec general practitioners (GPs) on LD diagnosis and management of patients bitten by infected ticks are described...
May 22, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28529879/beyond-the-raccoon-roundworm-the-natural-history-of-non-raccoon-baylisascaris-species-in-the-new-world
#9
REVIEW
Sarah G H Sapp, Pooja Gupta, Melissa K Martin, Maureen H Murray, Kevin D Niedringhaus, Madeleine A Pfaff, Michael J Yabsley
A total of 10 species of Baylisascaris, a genus of ascaridoid nematodes, occur worldwide and 6 of them occur in the New World. Most of the Baylisascaris species have a similar life cycle with carnivorous mammals or marsupials serving as definitive hosts and a smaller prey host serving as paratenic (or intermediate) hosts. However, one species in rodents is unique in that it only has one host. Considerable research has been conducted on B. procyonis, the raccoon roundworm, as it is a well-known cause of severe to fatal neurologic disease in humans and many wildlife species...
August 2017: International Journal for Parasitology. Parasites and Wildlife
https://www.readbyqxmd.com/read/28497257/-therapy-of-migranes
#10
D Holle-Lee, S Nägel, C Gaul
In migraine attack treatment analgesics such as nonsteroidal anti-inflammatory drugs and triptans can be utilized. The efficacy of acute attack treatment is relevant to prevent migraine chronification. For prophylactic treatment β‑blockers, tricyclic antidepressants, flunarizine, antiepileptics and onabotulinumtoxin A are available. There is evidence that some other substances (e. g. sartans) are also efficacious in this regard. Furthermore, nondrug approaches are essential in migraine therapy. Early education and prophylactic treatment of patients at risk may prevent from medication overuse headache...
May 11, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28473022/-clinical-manifestations-diagnosis-and-treatment-of-lyme-borreliosis
#11
Lukas Frans Ocias, Bo Bødker Jensen, Fredrikke Christie Knudtzen, Sigurdur Skarphedinsson, Ram Benny Dessau
Lyme borreliosis is an infection caused by the Borrelia burgdorferi sensu lato complex and transmitted by Ixodes ricinus ticks in Denmark. It can manifest itself in several different forms of which erythema migrans is the most common and is diagnosed by clinical assessment of the characteristic erythema. Laboratory support for the clinical diagnosis of other manifestations rests on the measurement of Borrelia-specific antibodies. Treatment is straight-forward with antibiotics such as penicillin. This paper reviews the clinical manifestations, diagnosis and treatment of this infection...
May 1, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28405553/lyme-disease-a-case-report-with-typical-and-atypical-lesions
#12
Anuj Sharma, Sandesh Guleria, Reena Sharma, Anita Sharma
Lyme disease is a multisystem infectious disease caused by the spirochete "Borrelia burgdorferi," which is transmitted by "Ixodes" tick, with skin being the most common and earliest organ to be affected. Diagnosis of erythema chronicum migrans (ECM), which is the characteristic lesion of early disease, may help in early treatment and prevention of complications. Here, we are reporting a case of Lyme disease in a 10-year-old young boy from a non-endemic zone of Himachal Pradesh, who presented with typical as well as atypical ECM lesions...
March 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28363038/baylisascaris-procyonis-larva-migrans-in-two-captive-north-american-beavers-castor-canadensis
#13
Isabelle Desprez, Michael J Yabsley, Susan B Fogelson, Jill A Hicks, Renee Barber, Izidora Sladakovic, Scott A Secrest, Stephen J Divers, Jörg Mayer
Baylisascaris procyonis larva migrans was diagnosed in two North American beavers ( Castor canadensis ) belonging to a zoological park in Clarke County, Georgia. Both beavers presented with neurological signs. One beaver died naturally and despite attempted treatment, the other beaver was euthanatized because of severe clinical signs and poor prognosis. Histologic evaluation of the beavers revealed evidence of parasitic migration characterized by several lesions, including eosinophilic granulomas in various organs, as well as necrotizing eosinophilic and lymphoplasmacytic to granulomatous polioencephalitis, leukoencephalitis and cervical leukomyelitis...
March 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28291638/lyme-disease-emergency-department-considerations
#14
Nathan D Applegren, Chadd K Kraus
BACKGROUND: Lyme disease (LD) is the most common vector-borne illness in North America. Reported cases of LD have increased from approximately 10,000 cases annually in 1991 to >25,000 cases in 2014. Greater recognition, enhanced surveillance, and public education have contributed to the increased prevalence, as have geographic expansion and the number of infected ticks. Cases are reported primarily in the Northeastern United States, Wisconsin, and Minnesota, with children having the highest incidence of LD among all age groups...
June 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28283015/-cutaneous-larva-migrans-in-turkey-an-imported-case-report
#15
Meliha Çağla Sönmezer, Şebnem Erdinç, Necla Tülek, Cahit Babür, Ayşe Büyükdemirci, Tuba İlgar, Günay Ertem
Cutaneous larva migrans (CLM) is a parasitic infection most commonly found in tropical and subtropical areas. However, with the ease and increase of foreign travel to many countries around the world, the infection is not limited to these areas. CLM is an erythematous, serpiginous infection with skin eruption caused by percutaneous penetration of the larvae to the skin. In this report, a case diagnosed as imported CLM after an Amazon trip and treated with albendazole was presented. A 36 year-old male patient admitted to infectious diseases clinic with intense itching, erythematous, raised, streaklike serpiginious eruptionand some redness at bilateral foot especially at the right foot for about one week...
January 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28277054/symptom-load-and-general-function-among-patients-with-erythema-migrans-a-prospective-study-with-a-1-year-follow-up-after-antibiotic-treatment-in-norwegian-general-practice
#16
RANDOMIZED CONTROLLED TRIAL
Knut Eirik Eliassen, Reidar Hjetland, Harald Reiso, Morten Lindbæk, Hedda Tschudi-Madsen
OBJECTIVE: Promptly treated erythema migrans (EM) has good prognosis. However, some patients report persistent symptoms. Do patients with EM have more symptoms than the general population? We describe individual symptoms and general function in EM-patients at time of diagnosis and one year after treatment. DESIGN: Prospective study with 1-year follow up after treatment. Questionnaires included a modified version of the Subjective Health Complaints Inventory, comprising three additional Lyme borreliosis (LB) related symptoms...
March 2017: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/28236088/-cutaneous-manifestations-of-lyme-disease-pitfalls-in-the-serological-diagnostic-workup
#17
M Glatz, R R Müllegger
Serology, the detection of B. burgdorferi-specific IgM and IgG serum antibodies, is the most common laboratory test to diagnose cutaneous manifestations of Lyme disease. In a two-tiered approach, an ELISA is used as a screening test. A positive or equivocal ELISA result needs confirmation by a specific immunoblot. The sensitivity of this approach reaches 80-95%. The diagnosis of erythema migrans is based on its typical clinical appearance. Serology is only indicated in atypical cases. In contrast, serology is mandatory in the diagnostic workup of borrelial lymphocytoma and acrodermatitis chronica atrophicans...
April 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28078983/cutaneous-larva-migrans
#18
Alexander K C Leung, Benjamin Barankin, Kam Lun Hon
BACKGROUND: Cutaneous larva migrans is one of the most common skin diseases reported in travelers returning from tropical regions. Western physicians, however, are often not familiar of this condition. OBJECTIVE: To review in depth the epidemiology, pathophysiology, clinical manifestations, complications, and treatment of cutaneous larva migrans. METHODS: A PubMed search was completed in Clinical Queries using the key term "cutaneous larva migrans"...
January 10, 2017: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28049383/a-lyme-borreliosis-diagnosis-probability-score-no-relation-with-antibiotic-treatment-response
#19
Violeta T Briciu, Mirela Flonta, Daniel Leucuţa, Dumitru Cârstina, Doina F Ţăţulescu, Mihaela Lupşe
OBJECTIVES: (1) To describe epidemiological and clinical data of patients that present with the suspicion of Lyme borreliosis (LB); (2) to evaluate a previous published score that classifies patients on the probability of having LB, following-up patients' clinical outcome after antibiotherapy. METHODS: Inclusion criteria: patients with clinical manifestations compatible with LB and Borrelia (B.) burgdorferi positive serology, hospitalized in a Romanian hospital between January 2011 and October 2012...
May 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28007428/topical-azithromycin-for-the-prevention-of-lyme-borreliosis-a-randomised-placebo-controlled-phase-3-efficacy-trial
#20
RANDOMIZED CONTROLLED TRIAL
Michael Schwameis, Thomas Kündig, Gustave Huber, Luzi von Bidder, Lorenz Meinel, Roland Weisser, Elisabeth Aberer, Georg Härter, Thomas Weinke, Tomas Jelinek, Gerd Fätkenheuer, Uwe Wollina, Gerd-Dieter Burchard, Roland Aschoff, Ruth Nischik, Gerhard Sattler, Georg Popp, Wolfgang Lotte, Dirk Wiechert, Gerald Eder, Olga Maus, Petra Staubach-Renz, Andrea Gräfe, Veronika Geigenberger, Ingomar Naudts, Michael Sebastian, Norbert Reider, Ridwan Weber, Marc Heckmann, Emil C Reisinger, Georg Klein, Johannes Wantzen, Bernd Jilma
BACKGROUND: Lyme borreliosis develops in 1-5% of individuals bitten by ticks, but with a diagnostic gap affecting up to 30% of patients, a broadly applicable pharmacological prevention strategy is needed. Topical azithromycin effectively eradicated Borrelia burgdorferi sensu lato from the skin in preclinical studies. We assessed its efficacy in human beings. METHODS: In this randomised, double-blind, placebo-controlled, multicentre trial done in 28 study sites in Germany and Austria, adults were equally assigned to receive topical 10% azithromycin or placebo twice daily for 3 consecutive days, within 72 h of a tick bite being confirmed...
March 2017: Lancet Infectious Diseases
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