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migrane treatment

Setareh Jahfari, Agnetha Hofhuis, Manoj Fonville, Joke van der Giessen, Wilfrid van Pelt, Hein Sprong
BACKGROUND: Tick-borne diseases are the most prevalent vector-borne diseases in Europe. Knowledge on the incidence and clinical presentation of other tick-borne diseases than Lyme borreliosis and tick-borne encephalitis is minimal, despite the high human exposure to these pathogens through tick bites. Using molecular detection techniques, the frequency of tick-borne infections after exposure through tick bites was estimated. METHODS: Ticks, blood samples and questionnaires on health status were collected from patients that visited their general practitioner with a tick bite or erythema migrans in 2007 and 2008...
October 2016: PLoS Neglected Tropical Diseases
Stefano Veraldi, Luisa Angileri, Bethsabeth Abigail Parducci, Gianluca Nazzaro
No abstract text is available yet for this article.
August 10, 2016: Journal of Dermatological Treatment
Jacob L Ogdee, Scott E Henke, David B Wester, Alan M Fedynich
Baylisascaris procyonis is a nematode whose definitive host is the raccoon (Procyon lotor). Adult parasites are not particularly pathogenic to raccoons; however, larvae in intermediate hosts can cause visceral, ocular, and neural larva migrans. Humans serve as dead-end hosts and pathological responses are similar as those found in infected intermediate hosts. Infected raccoons expose intermediate hosts through their feces, which can contain millions of B. procyonis eggs. Our objective was to determine how the quantity and viability of B...
August 19, 2016: Journal of Parasitology
Knut Eirik Eliassen, Dag Berild, Harald Reiso, Nils Grude, Karen Sofie Christophersen, Cecilie Finckenhagen, Morten Lindbæk
The first stage of Lyme borreliosis (LB) is mainly the typical skin lesion, erythema migrans (EM), which is estimated to comprise 80-90% of all LB cases. However, the reporting of, and the actual incidence of LB varies throughout Europe. Studies from Sweden and Holland have found EM incidences varying from 53 to 464 EM/100,000 inhabitants/year. Under-reporting of LB is common and a coefficient of three to reach a realistic estimate is suggested. In Norway, it is mandatory to report only the second and third LB stages to the National Institute of Public Health...
June 30, 2016: Ticks and Tick-borne Diseases
John N Aucott, Mark J Soloski, Alison W Rebman, Lauren A Crowder, Lauren J Lahey, Catriona A Wagner, William H Robinson, Kathleen T Bechtold
Approximately 10% to 20% of patients optimally treated for early Lyme disease develop persistent symptoms of unknown pathophysiology termed posttreatment Lyme disease syndrome (PTLDS). The objective of this study was to investigate associations between PTLDS and immune mediator levels during acute illness and at several time points following treatment. Seventy-six participants with physician-documented erythema migrans and 26 healthy controls with no history of Lyme disease were enrolled. Sixty-four cytokines, chemokines, and inflammatory markers were measured at each visit for a total of 6 visits over 1 year...
September 2016: Clinical and Vaccine Immunology: CVI
Ingo Stock
Lyme disease (Lyme borreliosis) is a systemic infectious disease that can present in a variety of clinical manifestations. The disease is caused by a group of spirochaetes--Borrelia burgdorferi sensu lato or Lyme borrelia--that are transmitted to humans by the bite of Ixodes ticks. Lyme disease is the most common arthropode-borne infectious disease in many European countries including Germany. Early localized infection is typically manifested by an erythema migrans skin lesion, in rarer cases as a borrelial lymphocytoma...
May 2016: Medizinische Monatsschrift Für Pharmazeuten
Matthew P Vasievich, Jose Dario Martinez Villarreal, Kenneth J Tomecki
The popularity of international travel continues to increase among Americans, even though they often experience subsequent illness on return from their journey. The pathogens responsible are not necessarily endemic to the destination itself but are often the result of poor sanitary conditions or activities engaged in while away. Skin disease ranks third among all medical concerns in returning travelers. This review addresses the pathogenesis, epidemiology, clinical presentation, and treatment of the most common skin diseases in returning travelers: insect bites and bedbugs, cutaneous larva migrans, scabies, tungiasis, myiasis, leishmaniasis, viral exanthems, and marine envenomation...
June 25, 2016: American Journal of Clinical Dermatology
Vera Maraspin, Mirijam Nahtigal Klevišar, Eva Ružić-Sabljić, Lara Lusa, Franc Strle
BACKGROUND: Information on the course and outcome of borrelial lymphocytoma (BL) is limited. METHODS: The study comprised 144 adult patients (75 female, 69 male; median age, 49 years) who had BL diagnosed at a single center between 1986 and 2014 and were followed up for 1 year. RESULTS: BL was located on the breast in 106 patients (73.6%), on the ear lobe in 27 (18.8%), and elsewhere in 11 (7.6%). The median duration of BL before diagnosis was 27 days (interquartile range [IQR], 9-68 days)...
October 1, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Erica Weitzner, Paul Visintainer, Gary P Wormser
BACKGROUND: Lyme disease is the most common vector-borne infection in the United States with 300,000 estimated cases per year. OBJECTIVE: The purpose of this study was to compare the presenting clinical features and long-term outcome of males versus females with culture-confirmed early Lyme disease. METHODS: 174 males and 109 females with culture-confirmed erythema migrans were entered into a prospective study with follow-up visits scheduled at six months, 12 months and annually thereafter for up to 20 years...
August 2016: Diagnostic Microbiology and Infectious Disease
Di-Qing Luo, Yu-Hua Liang, Xi-Qing Li, Yu-Kun Zhao, Fang Wang, Rashmi Sarkar
Cutaneous pili migrans and creeping eruption caused by parasitic diseases may present as a moving linear lesion in skin. The former, caused by a hair shaft or fragment embedded in the superficial skin or middle dermis, is a rare condition characterized by creeping eruption with a black line observed at the advancing end. In exceptionally rare instance, the hair grows inside the skin and burrows in the uppermost dermis, such a condition has been called "ingrown hair."We report a 30-year-old Chinese man, who was accustomed to pull or extrude the beard hairs, with 1-year history of slowly extending black linear eruption on his right chin...
May 2016: Medicine (Baltimore)
Katarina Ogrinc, Lara Lusa, Stanka Lotrič-Furlan, Petra Bogovič, Daša Stupica, Tjaša Cerar, Eva Ružić-Sabljić, Franc Strle
BACKGROUND: Information on the course and outcome of early European Lyme neuroborreliosis is limited. METHODS: The study comprised 77 patients (38 males, 39 females; median age, 58 years) diagnosed with painful meningoradiculitis (Bannwarth syndrome) who were followed up for 1 year at a single center. RESULTS: Duration of neurological symptoms before diagnosis was 30 (interquartile range, 14-50) days. The most frequent symptoms/signs were radicular pain (100%), sleep disturbances (75...
August 1, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Gabriel Torbahn, Heidelore Hofmann, Roman Allert, Michael H Freitag, Rick Dersch, Volker Fingerle, Harriet Sommer, Edith Motschall, Jörg J Meerpohl, Christine Schmucker
BACKGROUND: Erythema migrans represents an early cutaneous and most common manifestation of Lyme borreliosis. Recommendations regarding pharmacological agents, dose and duration of treatment are subject of intense debate. This review aims to explore differences in efficacy and safety between pharmacological treatments and control treatment. METHODS: To identify relevant studies, we will conduct a systematic literature search. We will include randomised controlled trials (RCTs) and non-RCTs...
2016: Systematic Reviews
Edgar Sanchez, Edouard Vannier, Gary P Wormser, Linden T Hu
IMPORTANCE: Lyme disease, human granulocytic anaplasmosis (HGA), and babesiosis are emerging tick-borne infections. OBJECTIVE: To provide an update on diagnosis, treatment, and prevention of tick-borne infections. EVIDENCE REVIEW: Search of PubMed and Scopus for articles on diagnosis, treatment, and prevention of tick-borne infections published in English from January 2005 through December 2015. FINDINGS: The search yielded 3550 articles for diagnosis and treatment and 752 articles for prevention...
April 26, 2016: JAMA: the Journal of the American Medical Association
Shalini Thapar Laroia, Archana Rastogi, Chhagan Bihari, Ajeet Singh Bhadoria, Shiv Kumar Sarin
INTRODUCTION: Hepatic visceral larva migrans (VLM) is an uncommon parasitic manifestation seen in the liver. It presents as coalescing, conglomerated, or solitary abscess cavities in the liver on imaging. We conducted a retrospective clinico-radiological analysis of 24 patients with biopsy proven VLM who were reviewed and followed up at our tertiary liver institute over a period of 4 years. MATERIALS AND METHODS: The study was performed to correlate the radiological features and imaging response to therapy for hepatic VLM...
January 2016: Tropical Parasitology
Carlos Graeff-Teixeira, Alessandra Loureiro Morassutti, Kevin R Kazacos
Baylisascaris procyonis, the raccoon roundworm, infects a wide range of vertebrate animals, including humans, in which it causes a particularly severe type of larva migrans. It is an important cause of severe neurologic disease (neural larva migrans [NLM]) but also causes ocular disease (OLM; diffuse unilateral subacute neuroretinitis [DUSN]), visceral larva migrans (VLM), and covert/asymptomatic infections. B. procyonis is common and widespread in raccoons, and there is increasing recognition of human disease, making a clinical consideration of baylisascariasis important...
April 2016: Clinical Microbiology Reviews
A Panés-Rodríguez, L Piera-Tuneu, A López-Pestaña, N Ormaetxea-Pérez, P Gutiérrez-Támara, S Ibarbia-Oruezabal, A Tuneu-Valls
INTRODUCTION: Cutaneous larva migrans (LM) infection forms a serpiginous eruption caused by the migration of nematode helminths through the epidermis. The parasites are acquired when the skin comes into contact with soil contaminated by the feces of infected animals. Until now, infections have been believed to be imported from tropical and subtropical regions. Our aim was to study cases of cutaneous LM diagnosed in residents of the Spanish province of Guipúzcoa who had not recently traveled to such regions...
June 2016: Actas Dermo-sifiliográficas
Steven M Callister, Dean A Jobe, Aleksandra Stuparic-Stancic, Misato Miyamasu, Jeff Boyle, Raymond J Dattwyler, Paul M Arnaboldi
BACKGROUND: Current serodiagnostics for Lyme disease lack sensitivity during early disease, and cannot determine treatment response. We evaluated an assay based on QuantiFERON technology utilizing peptide antigens derived from Borrelia burgdorferi to stimulate interferon-gamma (IFN-γ) release as an alternative to serodiagnosis for the laboratory detection of Lyme disease. METHODS: Blood was obtained from patients with erythema migrans before (n = 29) and 2 months after (n = 27) antibiotic therapy...
May 15, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
V D Zavoikin, N I Tumolskaya, M V Mazmanyan, O P Zelya, D V Tikhonova
The paper gives the results of treatment with micronized albendazole (Gelmodol-BM, World Medicine, UK) in 87 patients of the Department of Medical Parasitology and Tropical Diseases, Clinical and Diagnostic Center, Clinical Center, I.M.Sechenov First Moscow State Medical University. Thirty-two patients with echinococcosis 8 with alveococcosis (including 4 inoperable patients), 10 with ascariasis, 10 with toxocariasis, 15 with enterobiasis, and 12 people diagnosed with larva migrans were treated in 2013-2014...
October 2015: Meditsinskaia Parazitologiia i Parazitarnye Bolezni
Adriana R Marques
PURPOSE OF REVIEW: Lyme disease, caused by the spirochete Borrelia burgdorferi, is the most common tick-borne illness in the United States and Europe. Lyme disease usually begins with the characteristic skin lesion, erythema migrans, at the site of the tick bite. Following hematogenous dissemination, neurologic, cardiac, and/or rheumatologic involvement may occur. Neurologic involvement occurs in up to 15% of untreated B. burgdorferi infection and neurologists should be familiar with its diagnosis and management...
December 2015: Continuum: Lifelong Learning in Neurology
B Chomel
Lyme disease is among the most frequently diagnosed zoonotic tick-borne diseases worldwide. The number of human cases has been on the increase since the first recognition of its aetiological agent. Lyme disease is caused by spirochete bacteria belonging to the genus Borrelia, with B. burgdorferi sensu stricto (s.s.) found in the Americas, and B. afzelii and B. garinii, in addition to B. burgdorferi s.s., in Europe and Asia. Environmental factors, such as human encroachment onto habitats favourable to ticks and their hosts, reduced deforestation, increased human outdoor activities, and climatic factors favouring a wider distribution of tick vectors, have enhanced the impact of the disease on both humans and animals...
August 2015: Revue Scientifique et Technique
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