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https://www.readbyqxmd.com/read/28405553/lyme-disease-a-case-report-with-typical-and-atypical-lesions
#1
Anuj Sharma, Sandesh Guleria, Reena Sharma, Anita Sharma
Lyme disease is a multisystem infectious disease caused by the spirochete "Borrelia burgdorferi," which is transmitted by "Ixodes" tick, with skin being the most common and earliest organ to be affected. Diagnosis of erythema chronicum migrans (ECM), which is the characteristic lesion of early disease, may help in early treatment and prevention of complications. Here, we are reporting a case of Lyme disease in a 10-year-old young boy from a non-endemic zone of Himachal Pradesh, who presented with typical as well as atypical ECM lesions...
March 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28363038/baylisascaris-procyonis-larva-migrans-in-two-captive-north-american-beavers-castor-canadensis
#2
Isabelle Desprez, Michael J Yabsley, Susan B Fogelson, Jill A Hicks, Renee Barber, Izidora Sladakovic, Scott A Secrest, Stephen J Divers, Jörg Mayer
Baylisascaris procyonis larva migrans was diagnosed in two North American beavers ( Castor canadensis ) belonging to a zoological park in Clarke County, Georgia. Both beavers presented with neurological signs. One beaver died naturally and despite attempted treatment, the other beaver was euthanatized because of severe clinical signs and poor prognosis. Histologic evaluation of the beavers revealed evidence of parasitic migration characterized by several lesions, including eosinophilic granulomas in various organs, as well as necrotizing eosinophilic and lymphoplasmacytic to granulomatous polioencephalitis, leukoencephalitis and cervical leukomyelitis...
March 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28291638/lyme-disease-emergency-department-considerations
#3
Nathan D Applegren, Chadd K Kraus
BACKGROUND: Lyme disease (LD) is the most common vector-borne illness in North America. Reported cases of LD have increased from approximately 10,000 cases annually in 1991 to >25,000 cases in 2014. Greater recognition, enhanced surveillance, and public education have contributed to the increased prevalence, as have geographic expansion and the number of infected ticks. Cases are reported primarily in the Northeastern United States, Wisconsin, and Minnesota, with children having the highest incidence of LD among all age groups...
March 10, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28283015/-cutaneous-larva-migrans-in-turkey-an-imported-case-report
#4
Meliha Çağla Sönmezer, Şebnem Erdinç, Necla Tülek, Cahit Babür, Ayşe Büyükdemirci, Tuba İlgar, Günay Ertem
Cutaneous larva migrans (CLM) is a parasitic infection most commonly found in tropical and subtropical areas. However, with the ease and increase of foreign travel to many countries around the world, the infection is not limited to these areas. CLM is an erythematous, serpiginous infection with skin eruption caused by percutaneous penetration of the larvae to the skin. In this report, a case diagnosed as imported CLM after an Amazon trip and treated with albendazole was presented. A 36 year-old male patient admitted to infectious diseases clinic with intense itching, erythematous, raised, streaklike serpiginious eruptionand some redness at bilateral foot especially at the right foot for about one week...
January 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28277054/symptom-load-and-general-function-among-patients-with-erythema-migrans-a-prospective-study-with-a-1-year-follow-up-after-antibiotic-treatment-in-norwegian-general-practice
#5
Knut Eirik Eliassen, Reidar Hjetland, Harald Reiso, Morten Lindbæk, Hedda Tschudi-Madsen
OBJECTIVE: Promptly treated erythema migrans (EM) has good prognosis. However, some patients report persistent symptoms. Do patients with EM have more symptoms than the general population? We describe individual symptoms and general function in EM-patients at time of diagnosis and one year after treatment. DESIGN: Prospective study with 1-year follow up after treatment. Questionnaires included a modified version of the Subjective Health Complaints Inventory, comprising three additional Lyme borreliosis (LB) related symptoms...
March 2017: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/28236088/-cutaneous-manifestations-of-lyme-disease-pitfalls-in-the-serological-diagnostic-workup
#6
M Glatz, R R Müllegger
Serology, the detection of B. burgdorferi-specific IgM and IgG serum antibodies, is the most common laboratory test to diagnose cutaneous manifestations of Lyme disease. In a two-tiered approach, an ELISA is used as a screening test. A positive or equivocal ELISA result needs confirmation by a specific immunoblot. The sensitivity of this approach reaches 80-95%. The diagnosis of erythema migrans is based on its typical clinical appearance. Serology is only indicated in atypical cases. In contrast, serology is mandatory in the diagnostic workup of borrelial lymphocytoma and acrodermatitis chronica atrophicans...
February 24, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28078983/cutaneous-larva-migrans
#7
Alexander K C Leung, Benjamin Barankin, Kam Lun Hon
BACKGROUND: Cutaneous larva migrans is one of the most common skin diseases reported in travelers returning from tropical regions. Western physicians, however, are often not familiar of this condition. OBJECTIVE: To review in depth the epidemiology, pathophysiology, clinical manifestations, complications, and treatment of cutaneous larva migrans. METHODS: A PubMed search was completed in Clinical Queries using the key term "cutaneous larva migrans"...
January 10, 2017: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28049383/a-lyme-borreliosis-diagnosis-probability-score-no-relation-with-antibiotic-treatment-response
#8
Violeta T Briciu, Mirela Flonta, Daniel Leucuţa, Dumitru Cârstina, Doina F Ţăţulescu, Mihaela Lupşe
OBJECTIVES: (1) To describe epidemiological and clinical data of patients that present with the suspicion of Lyme borreliosis (LB); (2) to evaluate a previous published score that classifies patients on the probability of having LB, following-up patients' clinical outcome after antibiotherapy. METHODS: Inclusion criteria: patients with clinical manifestations compatible with LB and Borrelia (B.) burgdorferi positive serology, hospitalized in a Romanian hospital between January 2011 and October 2012...
May 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28007428/topical-azithromycin-for-the-prevention-of-lyme-borreliosis-a-randomised-placebo-controlled-phase-3-efficacy-trial
#9
Michael Schwameis, Thomas Kündig, Gustave Huber, Luzi von Bidder, Lorenz Meinel, Roland Weisser, Elisabeth Aberer, Georg Härter, Thomas Weinke, Tomas Jelinek, Gerd Fätkenheuer, Uwe Wollina, Gerd-Dieter Burchard, Roland Aschoff, Ruth Nischik, Gerhard Sattler, Georg Popp, Wolfgang Lotte, Dirk Wiechert, Gerald Eder, Olga Maus, Petra Staubach-Renz, Andrea Gräfe, Veronika Geigenberger, Ingomar Naudts, Michael Sebastian, Norbert Reider, Ridwan Weber, Marc Heckmann, Emil C Reisinger, Georg Klein, Johannes Wantzen, Bernd Jilma
BACKGROUND: Lyme borreliosis develops in 1-5% of individuals bitten by ticks, but with a diagnostic gap affecting up to 30% of patients, a broadly applicable pharmacological prevention strategy is needed. Topical azithromycin effectively eradicated Borrelia burgdorferi sensu lato from the skin in preclinical studies. We assessed its efficacy in human beings. METHODS: In this randomised, double-blind, placebo-controlled, multicentre trial done in 28 study sites in Germany and Austria, adults were equally assigned to receive topical 10% azithromycin or placebo twice daily for 3 consecutive days, within 72 h of a tick bite being confirmed...
March 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27900835/treatment-of-cutaneous-larva-migrans-with-a-single-session-of-carbon-dioxide-laser-a-study-of-ten-cases-in-the-philippines
#10
Livia Francine Soriano, Miriam Emily Piansay-Soriano
BACKGROUND: Cutaneous larva migrans (CLM) has a detrimental effect on patients' emotional and physical quality of life. Due to local unavailability of gold standard oral treatments for CLM, carbon dioxide laser was attempted. We present a case series where a single session of carbon dioxide laser treatment was associated with cessation of signs and symptoms of CLM. AIMS: The aim of this study was to assess the efficacy of a single session of carbon dioxide laser in the treatment of CLM...
November 29, 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27706159/molecular-detection-of-tick-borne-pathogens-in-humans-with-tick-bites-and-erythema-migrans-in-the-netherlands
#11
Setareh Jahfari, Agnetha Hofhuis, Manoj Fonville, Joke van der Giessen, Wilfrid van Pelt, Hein Sprong
BACKGROUND: Tick-borne diseases are the most prevalent vector-borne diseases in Europe. Knowledge on the incidence and clinical presentation of other tick-borne diseases than Lyme borreliosis and tick-borne encephalitis is minimal, despite the high human exposure to these pathogens through tick bites. Using molecular detection techniques, the frequency of tick-borne infections after exposure through tick bites was estimated. METHODS: Ticks, blood samples and questionnaires on health status were collected from patients that visited their general practitioner with a tick bite or erythema migrans in 2007 and 2008...
October 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27687255/treatment-of-hookworm-related-cutaneous-larva-migrans-with-topical-ivermectin
#12
Stefano Veraldi, Luisa Angileri, Bethsabeth Abigail Parducci, Gianluca Nazzaro
No abstract text is available yet for this article.
August 10, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27541828/permeability-and-viability-of-baylisascaris-procyonis-eggs-in-southern-texas-soils
#13
Jacob L Ogdee, Scott E Henke, David B Wester, Alan M Fedynich
Baylisascaris procyonis is a nematode whose definitive host is the raccoon ( Procyon lotor ). Adult parasites are not particularly pathogenic to raccoons; however, larvae in intermediate hosts can cause visceral, ocular, and neural larva migrans. Humans serve as dead-end hosts, and pathological responses are similar to those found in infected intermediate hosts. Infected raccoons expose intermediate hosts through their feces, which can contain millions of B. procyonis eggs. Our objective was to determine how the quantity and viability of B...
December 2016: Journal of Parasitology
https://www.readbyqxmd.com/read/27475874/incidence-and-antibiotic-treatment-of-erythema-migrans-in-norway-2005-2009
#14
Knut Eirik Eliassen, Dag Berild, Harald Reiso, Nils Grude, Karen Sofie Christophersen, Cecilie Finckenhagen, Morten Lindbæk
The first stage of Lyme borreliosis (LB) is mainly the typical skin lesion, erythema migrans (EM), which is estimated to comprise 80-90% of all LB cases. However, the reporting of, and the actual incidence of LB varies throughout Europe. Studies from Sweden and Holland have found EM incidences varying from 53 to 464 EM/100,000 inhabitants/year. Under-reporting of LB is common and a coefficient of three to reach a realistic estimate is suggested. In Norway, it is mandatory to report only the second and third LB stages to the National Institute of Public Health...
January 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/27358211/ccl19-as-a-chemokine-risk-factor-for-posttreatment-lyme-disease-syndrome-a-prospective-clinical-cohort-study
#15
John N Aucott, Mark J Soloski, Alison W Rebman, Lauren A Crowder, Lauren J Lahey, Catriona A Wagner, William H Robinson, Kathleen T Bechtold
Approximately 10% to 20% of patients optimally treated for early Lyme disease develop persistent symptoms of unknown pathophysiology termed posttreatment Lyme disease syndrome (PTLDS). The objective of this study was to investigate associations between PTLDS and immune mediator levels during acute illness and at several time points following treatment. Seventy-six participants with physician-documented erythema migrans and 26 healthy controls with no history of Lyme disease were enrolled. Sixty-four cytokines, chemokines, and inflammatory markers were measured at each visit for a total of 6 visits over 1 year...
September 2016: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/27348896/-lyme-disease-clinical-manifestations-and-treatment
#16
Ingo Stock
Lyme disease (Lyme borreliosis) is a systemic infectious disease that can present in a variety of clinical manifestations. The disease is caused by a group of spirochaetes--Borrelia burgdorferi sensu lato or Lyme borrelia--that are transmitted to humans by the bite of Ixodes ticks. Lyme disease is the most common arthropode-borne infectious disease in many European countries including Germany. Early localized infection is typically manifested by an erythema migrans skin lesion, in rarer cases as a borrelial lymphocytoma...
May 2016: Medizinische Monatsschrift Für Pharmazeuten
https://www.readbyqxmd.com/read/27344566/got-the-travel-bug-a-review-of-common-infections-infestations-bites-and-stings-among-returning-travelers
#17
REVIEW
Matthew P Vasievich, Jose Dario Martinez Villarreal, Kenneth J Tomecki
The popularity of international travel continues to increase among Americans, even though they often experience subsequent illness on return from their journey. The pathogens responsible are not necessarily endemic to the destination itself but are often the result of poor sanitary conditions or activities engaged in while away. Skin disease ranks third among all medical concerns in returning travelers. This review addresses the pathogenesis, epidemiology, clinical presentation, and treatment of the most common skin diseases in returning travelers: insect bites and bedbugs, cutaneous larva migrans, scabies, tungiasis, myiasis, leishmaniasis, viral exanthems, and marine envenomation...
October 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27334446/borrelial-lymphocytoma-in-adult-patients
#18
Vera Maraspin, Mirijam Nahtigal Klevišar, Eva Ružić-Sabljić, Lara Lusa, Franc Strle
BACKGROUND: Information on the course and outcome of borrelial lymphocytoma (BL) is limited. METHODS: The study comprised 144 adult patients (75 female, 69 male; median age, 49 years) who had BL diagnosed at a single center between 1986 and 2014 and were followed up for 1 year. RESULTS: BL was located on the breast in 106 patients (73.6%), on the ear lobe in 27 (18.8%), and elsewhere in 11 (7.6%). The median duration of BL before diagnosis was 27 days (interquartile range [IQR], 9-68 days)...
October 1, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27230991/comparison-of-males-versus-females-with-culture-confirmed-early-lyme-disease-at-presentation-and-at-11-20-years-after-diagnosis
#19
COMPARATIVE STUDY
Erica Weitzner, Paul Visintainer, Gary P Wormser
BACKGROUND: Lyme disease is the most common vector-borne infection in the United States with 300,000 estimated cases per year. OBJECTIVE: The purpose of this study was to compare the presenting clinical features and long-term outcome of males versus females with culture-confirmed early Lyme disease. METHODS: 174 males and 109 females with culture-confirmed erythema migrans were entered into a prospective study with follow-up visits scheduled at six months, 12 months and annually thereafter for up to 20 years...
August 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27175694/ingrowing-hair-a-case-report
#20
Di-Qing Luo, Yu-Hua Liang, Xi-Qing Li, Yu-Kun Zhao, Fang Wang, Rashmi Sarkar
Cutaneous pili migrans and creeping eruption caused by parasitic diseases may present as a moving linear lesion in skin. The former, caused by a hair shaft or fragment embedded in the superficial skin or middle dermis, is a rare condition characterized by creeping eruption with a black line observed at the advancing end. In exceptionally rare instance, the hair grows inside the skin and burrows in the uppermost dermis, such a condition has been called "ingrown hair."We report a 30-year-old Chinese man, who was accustomed to pull or extrude the beard hairs, with 1-year history of slowly extending black linear eruption on his right chin...
May 2016: Medicine (Baltimore)
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