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https://www.readbyqxmd.com/read/28350867/dissociation-between-skin-test-reactivity-and-anti-aeroallergen-ige-determinants-among-urban-brazilian-children
#1
Neuza M Alcantara-Neves, Rafael V Veiga, João C M Ponte, Sérgio S da Cunha, Silvia M Simões, Álvaro A Cruz, Maria Yazdanbakhsh, Sheila M Matos, Thiago Magalhães Silva, Camila A Figueiredo, Lain C Pontes-de-Carvalho, Laura C Rodrigues, Rosemeire L Fiaccone, Philip J Cooper, Maurício L Barreto
BACKGROUND: The dissociation between specific IgE and skin prick test reactivity to aeroallergens, a common finding in populations living in low and middle-income countries, has important implications for the diagnosis and treatment of allergic diseases. Few studies have investigated the determinants of this dissociation. In the present study, we explored potential factors explaining this dissociation in children living in an urban area of Northeast Brazil, focusing in particular on factors associated with poor hygiene...
2017: PloS One
https://www.readbyqxmd.com/read/28350860/uniquely-altered-transcripts-are-associated-with-immune-preservation-in-hiv-infection
#2
Michelle Zanoni, Ítalo Karmann Aventurato, James Hunter, Maria Cecilia Araripe Sucupira, Ricardo Sobhie Diaz
The mechanisms underlying host HIV control hold much promise in the search for a functional HIV cure. We investigated the host genomic signatures in elite controllers or rapid progressors following recent infection and the correlates of immune reconstitution during combination antiretroviral therapy. We characterized the HIV-specific longitudinal host transcriptional response of peripheral blood mononuclear cells from elite controllers, rapid progressors, immune responders and non-responders using a RT-qPCR array in a cohort of recently HIV-infected Brazilian individuals...
2017: PloS One
https://www.readbyqxmd.com/read/28350821/neuropathological-diagnoses-and-clinical-correlates-in-older-adults-in-brazil-a-cross-sectional-study
#3
Claudia K Suemoto, Renata E L Ferretti-Rebustini, Roberta D Rodriguez, Renata E P Leite, Luciana Soterio, Sonia M D Brucki, Raphael R Spera, Tarcila M Cippiciani, Jose M Farfel, Alexandre Chiavegatto Filho, Michel Satya Naslavsky, Mayana Zatz, Carlos A Pasqualucci, Wilson Jacob-Filho, Ricardo Nitrini, Lea T Grinberg
BACKGROUND: Clinicopathological studies are important in determining the brain lesions underlying dementia. Although almost 60% of individuals with dementia live in developing countries, few clinicopathological studies focus on these individuals. We investigated the frequency of neurodegenerative and vascular-related neuropathological lesions in 1,092 Brazilian admixed older adults, their correlation with cognitive and neuropsychiatric symptoms, and the accuracy of dementia subtype diagnosis...
March 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28346531/the-prevalence-of-trichomoniasis-and-associated-factors-among-women-treated-at-a-university-hospital-in-southern-brazil
#4
Fabiane Aguiar Dos Anjos Gatti, Etienne Ceolan, Fernando Salles Rodrigues Greco, Paula Costa Santos, Gabriel Baracy Klafke, Gisele Rodrigues de Oliveira, Andrea Von Groll, Ana Maria Barral de Martinez, Carla Vitola Gonçalves, Carlos James Scaini
BACKGROUND: Trichomoniasis is the most prevalent non-viral sexually transmitted disease (STD) in the world; however, it remains a neglected parasitic disease. This study aimed to determine the prevalence of trichomoniasis and its associated epidemiological factors among women treated at a hospital in southern Brazil. METHODOLOGY/PRINCIPAL FINDINGS: A cross-sectional study was performed to determine the prevalence of this infection in women treated at Hospital Universitário (HU) in Rio Grande, Rio Grande do Sul, Brazil, between January 2012 and January 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28344706/the-voluntariat-a-frieirean-framework-to-understand-the-nature-of-undergraduate-international-medical-experiences
#5
Seemi Qaiser, Helen Dimaras, Paul Hamel
Despite literature documenting limited and asymmetrical benefits along with ethical issues, short-term international volunteering is increasingly popular among North American university students as a perceived advantage when applying to professional healthcare schools or the job market. Academic institutions are also encouraging students to pursue international experiences in order to cultivate values as global citizens. These experiences are most typically limited to economically privileged students. Furthermore, international activities in developing countries often lack a pedagogy of social justice and may confirm a simplistic understanding of development...
December 2016: Canadian Medical Education Journal
https://www.readbyqxmd.com/read/28344031/culture-bound-syndromes-of-a-brazilian-amazon-riverine-population-tentative-correspondence-between-traditional-and-western-medicine-terms-and-possible-ethnopharmacological-implications
#6
E Pagani, J de F L Santos, E Rodrigues
ETHNOPHARMACOLOGICAL RELEVANCE: It is not always possible to correlate the "emic" terms to the "etic" ones during ethnopharmacological surveys, especially regarding those related to Culture-Bound Syndromes (CBS). Nevertheless, it is the role of ethnopharmacology to address these correlations, since they are the basis for the understanding of potential bioactives. AIM AND OBJECTIVES: This study reports the clinical manifestations and therapeutic resources used for the treatment of CBS among some riverine inhabitants of Brazilian Amazonia...
March 23, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28343780/propagation-of-brazilian-zika-virus-strains-in-static-and-suspension-cultures-using-vero-and-bhk-cells
#7
Alexander Nikolay, Leda R Castilho, Udo Reichl, Yvonne Genzel
The recent spread of Zika virus (ZIKV) in the Americas and the Pacific has reached alarming levels in more than 60 countries. However, relatively little is known about the disease on a virological and epidemiological level and its consequences for humans. Accordingly, a large demand for in vitro derived Brazilian ZIKV material to support in vitro and in vivo studies has arisen. However, a prompt supply of ZIKV and ZIKV antigens cannot be guaranteed as the production of this virus typically using Vero or C6/36 cell lines remains challenging...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28343621/fixed-flexion-knee-radiography-using-a-new-positioning-device-produced-highly-repeatable-measurements-of-joint-space-width-elsa-brasil-musculoskeletal-study-elsa-brasil-msk
#8
Rosa Weiss Telles, Luciana Costa-Silva, Luciana A C Machado, Rodrigo Citton Padilha Dos Reis, Sandhi Maria Barreto
OBJECTIVE: To describe the performance of a non-fluoroscopic fixed-flexion PA radiographic protocol with a new positioning device, developed for the assessment of knee osteoarthritis (OA) in Brazilian Longitudinal Study of Adult Health Musculoskeletal Study (ELSA-Brasil MSK). MATERIAL AND METHODS: A test-retest design including 19 adults (38 knee images) was conducted. Feasibility of the radiographic protocol was assessed by image quality parameters and presence of radioanatomic alignment according to intermargin distance (IMD) values...
March 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28343619/translation-and-validation-of-neck-bournemouth-questionnaire-to-brazilian-portuguese
#9
Danilo Harudy Kamonseki, Luísa Cedin, Jaqueline Tavares-Preto, Beatriz de Oliveira Peixoto, Sandro Rostelato-Ferreira
OBJECTIVE: To translate the Neck Bournemouth Questionnaire to Brazilian Portuguese, cross-culturally adapt, and to verify its validity and its reliability. METHODS: The development of the Brazilian version of Neck Bournemouth Questionnaire (Brazil-NBQ) was based on the guideline proposed by Guillemin. The applied process consisted of translation, back-translation, committee review and pre-test. Sixty-one volunteers presenting neck pain participated in this study...
March 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28343618/analysis-of-sexual-function-of-patients-with-dermatomyositis-and-polymyositis-through-self-administered-questionnaires-a-cross-sectional-study
#10
Fernando Henrique Carlos de Souza, Daniel Brito de Araújo, Clovis Artur Silva, Renata Miossi, Carmita Helena Najjar Abdo, Eloisa Bonfá, Samuel Katsuyuki Shinjo
INTRODUCTION: To date, there are no descriptions in the literature on gynecologic and sexual function evaluation in female patients with dermatomyositis (DM) and polymyositis (PM). OBJECTIVE: To assess sexual function in female patients with DM/PM. PATIENTS AND METHODS: This is a monocentric, cross-sectional study in which 23 patients (16 DM and 7 PM), with ages between 18 and 40 years, were compared to 23 healthy women of the same age group...
March 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28343617/epifibro-brazilian-fibromyalgia-registry-data-on-the-acr-classification-and-diagnostic-preliminary-criteria-fulfillment-and-the-follow-up-evaluation
#11
José Eduardo Martinez, Eduardo S Paiva, Marcelo C Rezende, Roberto E Heymann, Milton Helfenstein, Aline Ranzolin, Jose Roberto Provenza, Luiz Severiano Ribeiro, Eduardo J R Souza, Daniel P Feldman, Marcos Renato de Assis
INTRODUCTION: EpiFibro (Brazilian Epidemiological Study of Fibromyalgia) was created to study Fibromyalgia patients. Patients were included since 2011 according to the 1990 American College of Rheumatology Classification Criteria for Fibromyalgia (ACR1990). OBJECTIVES: To determine how many patients still fulfill the ACR1990 and the ACR2010 criteria in 2014; to determine the correlation between the impact of FM and to describe data on the follow-up evaluation. METHODS: This is a cross sectional study in a multicenter cohort of patients...
March 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28343324/a-new-species-of-neocosmocercella-baker-vaucher-1983-nematoda-cosmocercidae-a-parasite-of-phyllomedusa-vaillantii-boulenger-anura-phyllomedusidae-in-the-caxiuan%C3%A3-national-forest-eastern-amazon-brazil
#12
Ana Nunes Dos Santos, Allan Rodrigo Oliveira Rodrigues, Jeannie Nascimento Dos Santos, Cynthya Elizabeth González, Francisco Tiago de Vasconcelos Melo
Neocosmocercella bakeri n. sp. is described from the large intestine of Phyllomedusa vaillantii Boulenger collected in the Caxiuanã National Forest in the Eastern Brazilian Amazon. The new species is easily distinguished from the type-species of the genus, Neocosmocercella paraguayensis Baker & Vaucher, 1983 in possessing a triangular mouth opening with three simple lips (vs three bi-lobed lips and hexagonal mouth opening) and somatic papillae, which are absent in N. paraguayensis. The males of the new species are distinguished by the distribution of the sessile cloacal papillae and the dimensions of the gubernaculum, whereas the females are distinguished by their smaller size and opisthodelphic uterus...
March 25, 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28343232/genetic-polymorphisms-in-defb1-and-mirna202-are-involved-in-salivary-human-%C3%AE-defensin-1-levels-and-caries-experience-in-children
#13
Andrea Lips, Leonardo Santos Antunes, Lívia Azeredo Antunes, Júlia Guimarães Barcellos de Abreu, Driely Barreiros, Daniela Silva Barroso de Oliveira, Ana Carolina Batista, Paulo Nelson-Filho, Léa Assed Bezerra da Silva, Raquel Assed Bezerra da Silva, Gutemberg Gomes Alves, Erika Calvano Küchler
The antimicrobial peptides human β-defensins (hBDs) are encoded by β-defensin genes (DEFBs) and are possibly involved in caries susceptibility. In this study we aimed (1) to investigate the relationship between salivary hBDs and caries and (2) to evaluate the association of genetic polymorphisms in DEFB1 and microRNA202 (miRNA202) with salivary levels of hBDs and caries experience. Two data sets were available for this study, totalizing 678 Brazilian children. Dental examination and saliva collection were performed in all included children...
March 25, 2017: Caries Research
https://www.readbyqxmd.com/read/28343115/patterns-of-drinking-and-driving-offenses-among-nightclub-patrons-in-brazil
#14
Gabriela A Wagner, Zila M Sanchez
BACKGROUND: Brazil has a strict drinking and driving law known as the Brazilian "Dry Law". The aim of the present study was to investigate characteristics associated with the breaking of the Brazilian traffic law, on drinking and driving, at nightclub exit among a representative sample of nightclub patrons in the city of São Paulo, Brazil. METHODS: Portal survey realized with a two-stage cluster sampling survey design to collect data from 2422 patrons at the entrance and 1822 patrons at the exit of 31 nightclubs in the city of São Paulo, Brazil...
March 23, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28342142/smoking-prevalence-among-users-of-primary-healthcare-units-in-brazil-the-role-of-religiosity
#15
Edson Zangiacomi Martinez, Flávia Masili Giglio, Natalia Akemi Yamada Terada, Anderson Soares da Silva, Miriane Lucindo Zucoloto
The objective of this cross-sectional study is to examine the association between religious involvement and tobacco use in a large representative sample of users of primary healthcare units of Ribeirão Preto, Southeast Brazil. Current and past smoking habits were determined among 1055 users of primary healthcare units. Participants' religiosity was measured using the DUREL questionnaire. The prevalence of smoking among men was 16.8% [95% confidence interval (CI) 12.0-22.5] and among women was 12.6% (95% CI 10...
March 24, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28341906/south-brazilian-wines-culturable-yeasts-associated-to-bottled-wines-produced-in-rio-grande-do-sul-and-santa-catarina
#16
Mauricio Ramírez-Castrillón, Sandra Denise Camargo Mendes, Patricia Valente
A comprehensive understanding of the presence and role of yeasts in bottled wines helps to know and control the organoleptic quality of the final product. The South Region of Brazil is an important wine producer, and the state of "Rio Grande do Sul" (RS) accounts for 90% of Brazilian wines. The state of "Santa Catarina" (SC) started the production in 1975, and is currently the fifth Brazilian producer. As there is little information about yeasts present in Brazilian wines, our main objective was to assess the composition of culturable yeasts associated to bottled wines produced in RS and SC, South of Brazil...
April 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28341282/the-state-of-the-surgical-workforce-in-brazil
#17
Mário C Scheffer, Aline G A Guilloux, Alicia Matijasevich, Benjamin B Massenburg, Saurabh Saluja, Nivaldo Alonso
BACKGROUND: A critical insufficiency of surgeons, anesthesiologists, and obstetricians exists around the world, leaving billions of people without access to safe operative care. The distribution of the surgical workforce in Brazil, however, is poorly described and rarely assessed. Though the surgical workforce is only one element in the surgical system, this study aimed to map and characterize the distribution of the surgical workforce in Brazil in order to stimulate discussion on future surgical policy reforms...
February 2017: Surgery
https://www.readbyqxmd.com/read/28340370/validation-of-comet-assay-in-oregon-r-and-wild-type-strains-of-drosophila-melanogaster-exposed-to-a-natural-radioactive-environment-in-brazilian-semiarid-region
#18
Cícero Jorge Verçosa, Aroldo Vieira de Moraes Filho, Ícaro Fillipe de Araújo Castro, Robson Gomes Dos Santos, Kenya Silva Cunha, Daniela de Melo E Silva, Ana Cristina Lauer Garcia, Julio Alejandro Navoni, Viviane Souza do Amaral, Claudia Rohde
Natural radiation of geological origin is a common phenomenon in Brazil, a country where radioactive agents such as uranium may be often found. As an unstable atom, uranium undergoes radioactive decay with the generation of a series of decay by-products, including radon, which may be highly genotoxic and trigger several pathological processes, among which cancer. Because it is a gas, radon may move freely between cracks and gaps in the ground, seeping upwards into the buildings and in the environment. In this study, two Drosophila melanogaster Meigen (Diptera, Drosophilidae) strains called Oregon-R and Wild (collected in a non-radioactive environment) were exposed to atmospheric radiation in the Lajes Pintadas city, in the semiarid zone of northeastern Brazil...
March 21, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28340367/insulin-resistance-is-associated-with-carotid-intima-media-thickness-in-non-diabetic-subjects-a-cross-sectional-analysis-of-the-elsa-brasil-cohort-baseline
#19
Itamar S Santos, Márcio S Bittencourt, Alessandra C Goulart, Maria Inês Schmidt, Maria de Fátima H S Diniz, Paulo A Lotufo, Isabela M Benseñor
BACKGROUND AND AIMS: Epidemiological studies have analyzed the association between carotid intima-media thickness (CIMT) and insulin resistance, glucose levels or glycated hemoglobin with mixed results. We aimed to evaluate the association between CIMT and homeostasis model assessment - insulin resistance (HOMA-IR), fasting and post-load plasma glucose and glycated hemoglobin in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) baseline. METHODS: We included 8028 participants (aged 35-74 years) without diabetes or overt cardiovascular disease who had complete CIMT data at baseline...
March 10, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28340263/myrciaria-dubia-an-amazonian-fruit-population-structure-and-its-implications-for-germplasm-conservation-and-genetic-improvement
#20
C F Nunes, T A Setotaw, M Pasqual, E A Chagas, E G Santos, D N Santos, C G B Lima, G M A Cançado
Myrciaria dubia (camu-camu) is an Amazon tree that produces a tart fruit with high vitamin C content. It is probably the fruit with the highest vitamin C content among all Brazilian fruit crops and it can be used to supplement daily vitamin C dose. This property has attracted the attention of consumers and, consequently, encouraged fruit farmers to produce it. In order to identify and select potential accessions for commercial exploitation and breeding programs, M. dubia has received considerable research attention...
March 22, 2017: Genetics and Molecular Research: GMR
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