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https://www.readbyqxmd.com/read/28227728/comparison-between-users-of-a-new-methodology-for-heart-sound-auscultation
#1
Ana Castro, Pedro Gomes, Sandra S Mattos, Miguel T Coimbra, Ana Castro, Pedro Gomes, Sandra S Mattos, Miguel T Coimbra, Ana Castro, Sandra S Mattos, Pedro Gomes, Miguel Y Coimbra
Auscultation is a routine exam and the first line of screening in heart pathologies. The objective of this study was to assess if using a new data collection system, the DigiScope Collector, with a guided and automatic annotation of heart auscultation, different levels of expertise/experience users could collect similar digital auscultations. Data were collected within the Heart Caravan Initiative (Paraíba, Brasil). Patients were divided into two study groups: Group 1 evaluated by a third year medical student (User 1), and an experienced nurse (User 2); Group 2 evaluated by User 2 and an Information Technology professional (User 3)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227686/novel-modular-2-dof-microsurgical-forceps-for-transoral-laser-microsurgeries-ergonomic-design-and-preliminary-evaluation
#2
Manish Chauhan, Giacinto Barresi, Nikhil Deshpande, Darwin G Caldwell, Leonardo S Mattos, Manish Chauhan, Giacinto Barresi, Nikhil Deshpande, Darwin G Caldwell, Leonardo S Mattos, Darwin G Caldwell, Giacinto Barresi, Leonardo S Mattos, Nikhil Deshpande, Manish Chauhan
Transoral Laser Microsurgeries (TLM) demand a great level of control and precision in intraoperative tissue manipulation. The optimal eradication of the diseased tissue is possible only with coordinated control of the laser aiming for incision and the microsurgical tools for orienting and stretching the tissue. However, the traditional microsurgical tools are long, single purpose, one degree-of-freedom (DOF), rigid tools with small range of motion and a normal grasping handle inducing non-ergonomic usage. This paper presents a novel, modular microsurgical tool to overcome the challenges of the traditional tools and improve the surgeon-tool usage experience...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227041/deformable-resection-process-map-for-intraoperative-cutting-guides
#3
Megumi Nakao, Kojiro Taura, Tetsuya Matsuda, Megumi Nakao, Kojiro Taura, Tetsuya Matsuda, Megumi Nakao, Kojiro Taura, Tetsuya Matsuda
In this paper, we will introduce the concept of deformable resection process mapping as a time-varying geometric guide for soft tissue tumor resection procedures. The deformable resection process map (RPM) estimates the local appearance of vascular structures after cuts as a novel guide. The RPM can be directly generated from patient-specific medical images using volumetric resampling techniques. Since user input of some cutting points is the only requirement for generating the RPM, the developed software will be directly available for clinical use to preview surgical procedures and intraoperative workflow management without time-consuming setups or additional workloads...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28193242/process-evaluation-of-a-cluster-randomised-trial-testing-a-pressure-ulcer-prevention-care-bundle-a-mixed-methods-study
#4
Shelley Roberts, Elizabeth McInnes, Tracey Bucknall, Marianne Wallis, Merrilyn Banks, Wendy Chaboyer
BACKGROUND: As pressure ulcers contribute to significant patient burden and increased health care costs, their prevention is a clinical priority. Our team developed and tested a complex intervention, a pressure ulcer prevention care bundle promoting patient participation in care, in a cluster-randomised trial. The UK Medical Research Council recommends process evaluation of complex interventions to provide insight into why they work or fail and how they might be improved. This study aimed to evaluate processes underpinning implementation of the intervention and explore end-users' perceptions of it, in order to give a deeper understanding of its effects...
February 13, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28148471/a-self-regulation-theory-based-asthma-management-mobile-app-for-adolescents-a-usability-assessment
#5
Adam Sage, Courtney Roberts, Lorie Geryk, Betsy Sleath, Deborah Tate, Delesha Carpenter
BACKGROUND: Self-regulation theory suggests people learn to influence their own behavior through self-monitoring, goal-setting, feedback, self-reward, and self-instruction, all of which smartphones are now capable of facilitating. Several mobile apps exist to manage asthma; however, little evidence exists about whether these apps employ user-centered design processes that adhere to government usability guidelines for mobile apps. OBJECTIVE: Building upon a previous study that documented adolescent preferences for an asthma self-management app, we employed a user-centered approach to assess the usability of a high-fidelity wireframe for an asthma self-management app intended for use by adolescents with persistent asthma...
February 1, 2017: JMIR Human Factors
https://www.readbyqxmd.com/read/28147704/pre-exposure-prophylaxis-prescribing-and-retention-in-care-among-heterosexual-women-at-a-community-based-comprehensive-sexual-health-clinic
#6
Oni J Blackstock, Viraj V Patel, Uriel Felsen, Connie Park, Sachin Jain
In the United States, heterosexual women account for 20% of new HIV infections. As a user-controlled HIV prevention method, pre-exposure prophylaxis (PrEP) has substantial potential to reduce new infections among women. However, among women, PrEP is vastly underutilized. To guide efforts to increase women-at-risk's PrEP use, we sought to describe the characteristics of women prescribed PrEP as well as their retention in PrEP care. We conducted a chart review of women who received care at a comprehensive sexual health clinic within a large urban health care system...
February 1, 2017: AIDS Care
https://www.readbyqxmd.com/read/28122093/a-dermatologist-s-guide-to-infection-screening-prior-to-initiating-immunosuppressive-therapy
#7
M G Ponzo, C H Hong
Dermatologists have within their armamentarium numerous immunosuppressant agents, both traditional and new, that are useful in the treatment of chronic cutaneous disorders such as autoimmune bullous diseases and psoriasis. It is imperative that users of these agents are aware of potential sequelae from therapy, particularly infections. In this review, we summarize the most common immunosuppressant medications currently used in dermatology, and provide recommendations for infection screening prior to initiating treatment...
January 2017: Skin Therapy Letter
https://www.readbyqxmd.com/read/28118107/patient-perspectives-on-the-ethical-implementation-of-a-rapid-learning-system-for-oncology-care
#8
Rochelle D Jones, Aaron N Sabolch, Erin Aakhus, Rebecca A Spence, Angela R Bradbury, Reshma Jagsi
INTRODUCTION: A rapid learning system (RLS) of health care harnesses data generated from routine patient care to create a virtuous cycle of data collection and analysis for quality improvement and research. The success of such systems depends on understanding patient perspectives regarding the ethical issues that arise from the ongoing implementation of this transformative concept. METHODS: An interview guide was designed to evaluate patient perspectives to inform the ethical implementation of an oncology RLS...
January 24, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28113237/see-it-with-your-own-eyes-marker-less-mobile-augmented-reality-for-radiation-awareness-in-the-hybrid-room
#9
Nicolas Loy Rodas, Fernando Barrera, Nicolas Padoy
GOAL: We present an approach to provide awareness to the harmful ionizing radiation generated during X-ray guided minimally invasive procedures. METHODS: A hand-held screen is used to display directly in the user's view information related to radiation safety in a mobile augmented reality (AR) manner. Instead of using markers, we propose a method to track the observer's viewpoint which relies on the use of multiple RGB-D sensors and combines equipment detection for tracking initialization with a KinectFusion-like approach for frame-to-frame tracking...
April 29, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28102899/b-type-natriuretic-peptide-guided-treatment-for-heart-failure
#10
REVIEW
Julie McLellan, Carl J Heneghan, Rafael Perera, Alison M Clements, Paul P Glasziou, Karen E Kearley, Nicola Pidduck, Nia W Roberts, Sally Tyndel, F Lucy Wright, Clare Bankhead
BACKGROUND: Heart failure is a condition in which the heart does not pump enough blood to meet all the needs of the body. Symptoms of heart failure include breathlessness, fatigue and fluid retention. Outcomes for patients with heart failure are highly variable; however on average, these patients have a poor prognosis. Prognosis can be improved with early diagnosis and appropriate use of medical treatment, use of devices and transplantation. Patients with heart failure are high users of healthcare resources, not only due to drug and device treatments, but due to high costs of hospitalisation care...
December 22, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28077345/tips-and-traps-lessons-from-codesigning-a-clinician-e-monitoring-tool-for-computerized-cognitive-behavioral-therapy
#11
Frederick Sundram, Susan J Hawken, Karolina Stasiak, Mathijs Fg Lucassen, Theresa Fleming, Matthew Shepherd, Andrea Greenwood, Raechel Osborne, Sally N Merry
BACKGROUND: Computerized cognitive behavioral therapy (cCBT) is an acceptable and promising treatment modality for adolescents with mild-to-moderate depression. Many cCBT programs are standalone packages with no way for clinicians to monitor progress or outcomes. We sought to develop an electronic monitoring (e-monitoring) tool in consultation with clinicians and adolescents to allow clinicians to monitor mood, risk, and treatment adherence of adolescents completing a cCBT program called SPARX (Smart, Positive, Active, Realistic, X-factor thoughts)...
January 11, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28045932/metavisitor-a-suite-of-galaxy-tools-for-simple-and-rapid-detection-and-discovery-of-viruses-in-deep-sequence-data
#12
Guillaume Carissimo, Marius van den Beek, Kenneth D Vernick, Christophe Antoniewski
Metavisitor is a software package that allows biologists and clinicians without specialized bioinformatics expertise to detect and assemble viral genomes from deep sequence datasets. The package is composed of a set of modular bioinformatic tools and workflows that are implemented in the Galaxy framework. Using the graphical Galaxy workflow editor, users with minimal computational skills can use existing Metavisitor workflows or adapt them to suit specific needs by adding or modifying analysis modules. Metavisitor works with DNA, RNA or small RNA sequencing data over a range of read lengths and can use a combination of de novo and guided approaches to assemble genomes from sequencing reads...
2017: PloS One
https://www.readbyqxmd.com/read/28008577/-licensing-of-pharmaceuticals-and-medical-devices-in-germany-weaknesses-and-opportunities
#13
D Reinhardt, M Wildner
The purpose of this study is to describe and compare the licensing of pharmaceuticals and medical devices in Germany. Weaknesses and opportunities of the respective processes are identified. Methods: To describe and compare the two approaches, a systematic literature review was conducted, followed by an archival analysis, guided by experts. Unstructured interviews were conducted with experts (users, financers, surveillants and producers) personally or by telephone to identify weaknesses and opportunities. The data were evaluated by content analysis according to Mayring and MAXQDA 11...
December 2016: Das Gesundheitswesen
https://www.readbyqxmd.com/read/27992949/age-stratified-outcome-of-genotype-guided-dosing-algorithm-for-acenocoumarol-and-phenprocoumon
#14
Yumao Zhang, Anthonius de Boer, Talitha I Verhoef, Felix Jm van der Meer, Saskia Le Cessie, Vangelis G Manolopoulos, Anke H Maitland-van der Zee
BACKGROUND: Age seemed to affect the interaction between coumarins and genotype in the acenocoumarol and phenprocoumon arm of the European pharmacogenetics of anticoagulant therapy (EU-PACT) trial. OBJECTIVES: To investigate the effect of genotype-guided dosing stratified by age and the potential factors causing a difference. PATIENTS/METHODS: Data from the acenocoumarol/phenprocoumon arm of the EU-PACT trial was used. The percentage of time below, above and in the therapeutic range (TTR) during the initial 12 weeks of therapy were compared between the genotype-guided group and the control group among younger (<75 years) and older (≥75 years) patients using independent t-test and adjust for sex, height, weight and co-medications using linear regression...
December 19, 2016: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/27986738/african-american-patients-with-cancer-talking-about-clinical-trials-tact-with-oncologists-during-consultations-evaluating-the-efficacy-of-tailored-health-messages-in-a-randomised-controlled-trial-the-tact-study-protocol
#15
R F Brown, R Davis, M Wilson Genderson, S Grant, D Cadet, M Lessard, J Alpert, J Ward, G Ginder
INTRODUCTION: Low rates of accrual of African-American (AA) patients with cancer to therapeutic clinical trials (CTs) represent a serious and modifiable racial disparity in healthcare that impedes the development of promising cancer therapies. Suboptimal physician-patient consultation communication is a barrier to the accrual of patients with cancer of any race, but communication difficulties are compounded with AA patients. Providing tailored health messages (THM) to AA patients and their physician about CTs has the potential to improve communication, lower barriers to accrual and ameliorate health disparities...
December 16, 2016: BMJ Open
https://www.readbyqxmd.com/read/27932337/development-of-a-critical-appraisal-tool-to-assess-the-quality-of-cross-sectional-studies-axis
#16
Martin J Downes, Marnie L Brennan, Hywel C Williams, Rachel S Dean
OBJECTIVES: The aim of this study was to develop a critical appraisal (CA) tool that addressed study design and reporting quality as well as the risk of bias in cross-sectional studies (CSSs). In addition, the aim was to produce a help document to guide the non-expert user through the tool. DESIGN: An initial scoping review of the published literature and key epidemiological texts was undertaken prior to the formation of a Delphi panel to establish key components for a CA tool for CSSs...
December 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/27897005/strategies-for-equitable-pharmacogenomic-guided-warfarin-dosing-among-european-and-african-american-individuals-in-a-clinical-population
#17
Laura K Wiley, Jacob P Vanhouten, David C Samuels, Melinda C Aldrich, Dan M Roden, Josh F Peterson, Joshua C Denny
The blood thinner warfarin has a narrow therapeutic range and high inter- and intra-patient variability in therapeutic doses. Several studies have shown that pharmacogenomic variants help predict stable warfarin dosing. However, retrospective and randomized controlled trials that employ dosing algorithms incorporating pharmacogenomic variants under perform in African Americans. This study sought to determine if: 1) including additional variants associated with warfarin dose in African Americans, 2) predicting within single ancestry groups rather than a combined population, or 3) using percentage African ancestry rather than observed race, would improve warfarin dosing algorithms in African Americans...
2016: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/27887587/experiences-of-support-in-working-toward-personal-recovery-goals-a-collaborative-qualitative-study
#18
Eva Biringer, Larry Davidson, Bengt Sundfør, Torleif Ruud, Marit Borg
BACKGROUND: Recovery can be understood as a subjective process guided by personal expectations, goals and hopes. The aim of the study was to explore how persons using a Community Mental Health Centre (CMHC) experienced that their expectations for treatment, and goals and hopes for recovery were supported by the health professionals during treatment. METHODS: Employing a hermeneutic-phenomenological approach, eight service users were interviewed about their expectations for treatment and their goals and hopes for recovery at the start of their contact with health professionals at a CMHC...
November 25, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27869583/patient-facing-technology-for-identification-of-copd-in-primary-care
#19
David Kevin Ahern, Donna Parker, Charles Eaton, Caitlin Rafferty, Joseph Wroblewski, Roberta Goldman
BACKGROUND: The proliferation of mobile devices and emergence of interoperable 'mHealth' apps is accelerating development and deployment of patient-facing risk assessments in primary care. The present study describes a user-centered design and an agile development approach to creation of an app for assessing lungfunction as part of a randomized controlled trial for the   dentification of chronic obstructive lung disease in primary care. METHOD: Seventeen patients recruited from a hospital-based, ambulatory family medicine clinic agreed to be videotaped while using the app, Lung Age, on a first-generation iPad prior to their provideR encounter...
July 15, 2016: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/27836856/health-professional-perspectives-on-the-management-of-multimorbidity-and-polypharmacy-for-older-patients-in-australia
#20
Kevin Peter Mc Namara, Bianca Daphne Breken, Hamzah Tariq Alzubaidi, J Simon Bell, James A Dunbar, Christine Walker, Andrea Hernan
BACKGROUND: delivering appropriate care for patients with multimorbidity and polypharmacy is increasingly challenging. Challenges for individual healthcare professions are known, but only little is known about overall healthcare team implementation of best practice for these patients. OBJECTIVE: to explore current approaches to multimorbidity management, and perceived barriers and enablers to deliver appropriate medications management for community-dwelling patients with multimorbidity and polypharmacy, from a broad range of healthcare professional (HCP) perspectives in Australia...
November 10, 2016: Age and Ageing
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