keyword
https://read.qxmd.com/read/38596869/evaluating-the-multiple-sulfur-isotope-signature-of-eoarchean-rocks-from-the-isua-supracrustal-belt-southwest-greenland-by-mc-icp-ms-volcanic-nutrient-sources-for-early-life
#21
JOURNAL ARTICLE
Jane E Macdonald, Patrick Sugden, Matthew Dumont, Kristoffer Szilas, Stijn Glorie, Alexander Simpson, Sarah Gilbert, Andrea Burke, Eva E Stüeken
On the anoxic Archean Earth, prior to the onset of oxidative weathering, electron acceptors were relatively scarce, perhaps limiting microbial productivity. An important metabolite may have been sulfate produced during the photolysis of volcanogenic SO2 gas. Multiple sulfur isotope data can be used to track this sulfur source, and indeed this record indicates SO2 photolysis dating back to at least 3.7 Ga, that is, as far back as proposed evidence of life on Earth. However, measurements of multiple sulfur isotopes in some key strata from that time can be challenging due to low sulfur concentrations...
2024: Geobiology
https://read.qxmd.com/read/38593409/a-comparison-of-scan-and-focal-sampling-in-estimating-activity-budgets-diet-composition-and-proximity-patterns-of-a-wild-pair-living-primate
#22
JOURNAL ARTICLE
Katherina Tesar, Eckhard W Heymann, Sofya Dolotovskaya
The choice of behavioral sampling method can impact the outcome of data collection, however, few direct comparisons between methods have been made. We compared the performance of instantaneous group scan sampling (scan sampling) and focal continuous sampling with variable session durations (focal sampling) in estimating activity patterns, diet composition, and spatial proximity in seven groups of wild coppery titi monkeys (Plecturocebus cupreus) in Peruvian Amazonia. We used a series of paired samples Wilcoxon tests to compare daily proportions of time allocated to each type of activity/food/proximity category in each sampling method...
October 20, 2023: Folia Primatologica; International Journal of Primatology
https://read.qxmd.com/read/38592722/olaparib-addition-to-maintenance-bevacizumab-therapy-in-ovarian-carcinoma-with-brca-like-genomic-aberrations
#23
RANDOMIZED CONTROLLED TRIAL
Philip C Schouten, Sandra Schmidt, Kerstin Becker, Holger Thiele, Peter Nürnberg, Lisa Richters, Corinna Ernst, Isabelle Treilleux, Jacques Medioni, Florian Heitz, Carmela Pisano, Yolanda Garcia, Edgar Petru, Sakari Hietanen, Nicoletta Colombo, Ignace Vergote, Shoji Nagao, Sabine C Linn, Eric Pujade-Lauraine, Isabelle Ray-Coquard, Philipp Harter, Eric Hahnen, Rita K Schmutzler
IMPORTANCE: Testing for homologous recombination deficiency is required for the optimal treatment of high-grade epithelial ovarian cancer. The search for accurate biomarkers is ongoing. OBJECTIVE: To investigate whether progression-free survival (PFS) and overall survival (OS) of patients with high-grade epithelial ovarian cancer treated with maintenance olaparib or placebo differed between patients with a tumor BRCA-like genomic profile and patients without a tumor BRCA-like profile...
April 1, 2024: JAMA Network Open
https://read.qxmd.com/read/38590394/associations-of-historical-redlining-with-bmi-and-waist-circumference-in-coronary-artery-risk-development-in-young-adults
#24
JOURNAL ARTICLE
Andrea S Richardson, Tamara Dubowitz, Kirsten M M Beyer, Yuhong Zhou, Kiarri N Kershaw, Waverly Duck, Feifei Ye, Robin Beckman, Penny Gordon-Larsen, James M Shikany, Catarina Kiefe
INTRODUCTION: Historical maps of racialized evaluation of mortgage lending risk (i.e., redlined neighborhoods) have been linked to adverse health outcomes. Little research has examined whether living in historically redlined neighborhoods is associated with obesity, differentially by race or gender. METHODS: This is a cross-sectional study to examine whether living in historically redlined neighborhoods is associated with BMI and waist circumference among Black and White adults in 1985-1986...
June 2024: AJPM Focus
https://read.qxmd.com/read/38590142/ensemble-learning-methods-of-inference-for-spatially-stratified-infectious-disease-systems
#25
JOURNAL ARTICLE
Jeffrey Peitsch, Gyanendra Pokharel, Shakhawat Hossain
Individual level models are a class of mechanistic models that are widely used to infer infectious disease transmission dynamics. These models incorporate individual level covariate information accounting for population heterogeneity and are generally fitted in a Bayesian Markov chain Monte Carlo (MCMC) framework. However, Bayesian MCMC methods of inference are computationally expensive for large data sets. This issue becomes more severe when applied to infectious disease data collected from spatially heterogeneous populations, as the number of covariates increases...
April 10, 2024: International Journal of Biostatistics
https://read.qxmd.com/read/38589323/socio-family-factors-predictive-of-adaptative-coping-post-covid-19-pandemic-in-nursing-students-from-a-private-university
#26
JOURNAL ARTICLE
Luz Enith Velásquez Restrepo, Gladys Judith Basto Hernández, María Nelcy Muñoz Astudillo
OBJECTIVE: To identify socio-academic and family functionality factors - communication, cohesion, and flexibility - as predictive stimuli of adaptive coping of nursing university students in the post-COVID-19 pandemic. METHODS: A cross-sectional descriptive study with stratified random sampling, with participation by 416 Nursing students from a private university in Pereira (Colombia), who answered a self-completed sociodemographic characterization survey, the Olson et al...
June 2023: Investigación y Educación en Enfermería
https://read.qxmd.com/read/38589219/intersectional-inequalities-in-paediatric-infectious-diseases-a-national-cohort-study-in-sweden
#27
JOURNAL ARTICLE
Samuel Videholm, Sven Arne Silfverdal, Per E Gustafsson
BACKGROUND: It is well known that socially deprived children are more likely to be hospitalised for infections. Less is known about how different social disadvantages interact. Therefore, we examine intersectional inequalities in overall, upper respiratory, lower respiratory, enteric and genitourinary infections in the first 5 years of life. METHODS: We conducted a population-based retrospective cohort study of Swedish children born between 1998 and 2015. Inequalities were examined using analysis of individual heterogeneity and discriminatory accuracy as the analytical framework...
April 8, 2024: Journal of Epidemiology and Community Health
https://read.qxmd.com/read/38588766/prevalence-and-costs-of-esophageal-strictures-in-the-united-states
#28
JOURNAL ARTICLE
Angela Z Xue, Chelsea Anderson, Cary C Cotton, Charles E Gaber, Cynthia Feltner, Evan Dellon
BACKGROUND AND AIMS: Esophageal strictures are a leading cause of dysphagia, but data regarding the epidemiology of esophageal strictures are limited. This study aimed to investigate the prevalence, healthcare utilization, and financial burden of esophageal strictures in the United States. METHODS: We performed a retrospective cohort study utilizing two large national insurance claims databases (MarketScan and Medicare). Using ICD-9 and -10 diagnostic codes, annual prevalence was calculated for both cohorts overall, as well as stratified by age and sex strata...
April 6, 2024: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/38587845/public-health-relevance-of-us-epa-air-quality-index-activity-recommendations
#29
JOURNAL ARTICLE
Robert D Brook, Sanjay Rajagopalan, Sadeer Al-Kindi
IMPORTANCE: Reducing exposure to fine particulate matter (<2.5 μm [PM2.5]) air pollution improves cardiopulmonary morbidity and mortality. However, the public health relevance of air quality index (AQI) activity guidelines under present-day environmental conditions in the US has not been critically assessed. OBJECTIVE: To evaluate the public health relevance of following PM2.5 AQI activity guidance in preventing serious atherosclerotic cardiovascular disease (ASCVD) and pulmonary events among adults in the US...
April 1, 2024: JAMA Network Open
https://read.qxmd.com/read/38585057/optimization-of-the-layer-location-of-extraction-wells-based-on-the-unpressurized-gas-transport-law
#30
JOURNAL ARTICLE
Runsheng Lv, Hengyi Guo, Lin Zhu, Xiaoming Ni
Protective layer mining is one of the most effective measures to control outbursts of coal seam gas in coal mines. Accurately grasping the overlying rock movement and pressure-relief gas migration patterns under protective layer mining conditions is a prerequisite for efficient surface coalbed methane extraction; it is the basis for green emission reduction in coal mines. A physical model was established using the Ji15 -33200 working face of Pingmei Shi Mine as the research object, and a method combining theoretical calculation and numerical simulation was used to obtain the overlying rock movement...
April 2, 2024: ACS Omega
https://read.qxmd.com/read/38584291/residence-based-inequalities-in-overweight-obesity-in-sub-saharan-africa-a-multivariate-non-linear-decomposition-analysis
#31
JOURNAL ARTICLE
Priscilla Atsu, Aliu Mohammed, Collins Adu, Richard Gyan Aboagye, Bright Opoku Ahinkorah, Abdul-Aziz Seidu
BACKGROUND: Overweight/obesity remains a major risk factor for non-communicable diseases and their associated morbidities and mortalities. Yet, limited studies have comprehensively examined factors contributing to the rural-urban disparities in overweight/obesity among women in sub-Saharan Africa. Thus, our study sought to decompose the rural-urban disparities in overweight/obesity among women in sub-Saharan Africa (SSA) using nationally representative datasets. METHODS: We performed a cross-sectional analysis of data from the Demographic and Health Surveys of 23 sub-Saharan African countries conducted from 2015 to 2022...
April 7, 2024: Tropical Medicine and Health
https://read.qxmd.com/read/38584234/failure-evolution-and-instability-prediction-of-fiber-reinforced-polymer-confined-cement-mortar-specimens-under-axial-compression
#32
JOURNAL ARTICLE
Jian Li, Jinwen Bai, Yanna Han, Guorui Feng, Xudong Shi, Junbiao Ma, Boqiang Cui, Kai Wang, Jiachen Mi
In geotechnical engineering, a large number of pillars are often left in underground space to support the overlying strata and protect the surface environment. To enhance pillar stability and prevent instability, this study proposes an innovative technology for pillar reinforcement. Specifically, local confinement of the pillar is achieved through fiber-reinforced polymer (FRP) strips, resulting in the formation of a more stable composite structure. In order to validate the effectiveness of this structural approach, acoustic emission characteristics and surface strain field characteristics were monitored during failure processes, while mathematical models were employed to predict specimen instability...
April 8, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38583459/blood-rna-biomarkers-for-tuberculosis-screening-in-people-living-with-hiv-before-antiretroviral-therapy-initiation-a-diagnostic-accuracy-study
#33
JOURNAL ARTICLE
Tiffeney Mann, Rishi K Gupta, Byron W P Reeve, Gcobisa Ndlangalavu, Aneesh Chandran, Amirtha P Krishna, Claire J Calderwood, Happy Tshivhula, Zaida Palmer, Selisha Naidoo, Desiree L Mbu, Grant Theron, Mahdad Noursadeghi
BACKGROUND: Undiagnosed tuberculosis remains a major threat for people living with HIV. Multiple blood transcriptomic biomarkers have shown promise for tuberculosis diagnosis. We sought to evaluate their diagnostic accuracy and clinical utility for systematic pre-antiretroviral therapy (ART) tuberculosis screening. METHODS: We enrolled consecutive adults (age ≥18 years) referred to start ART at a community health centre in Cape Town, South Africa, irrespective of symptoms...
April 4, 2024: Lancet Global Health
https://read.qxmd.com/read/38581199/gap-free-x-and-y-chromosome-assemblies-of-salix-arbutifolia-reveal-an-evolutionary-change-from-male-to-female-heterogamety-in-willows-without-a-change-in-the-position-of-the-sex-determining-locus
#34
JOURNAL ARTICLE
Yi Wang, Guang-Nan Gong, Yuan Wang, Ren-Gang Zhang, Elvira Hörandl, Zhi-Xiang Zhang, Deborah Charlesworth, Li He
In the Vetrix clade of Salix, a genus of woody flowering plants, sex determination involves chromosome 15, but an XY system has changed to a ZW system. We studied the detailed genetic changes involved. We used genome sequencing, with chromosome conformation capture (Hi-C) and PacBio HiFi reads to assemble chromosome level gap-free X and Y of Salix arbutifolia, and distinguished the haplotypes in the 15X- and 15Y-linked regions, to study the evolutionary history of the sex-linked regions (SLRs). Our sequencing revealed heteromorphism of the X and Y haplotypes of the SLR, with the X-linked region being considerably larger than the corresponding Y region, mainly due to accumulated repetitive sequences and gene duplications...
April 6, 2024: New Phytologist
https://read.qxmd.com/read/38580369/salt-intake-across-the-hypertension-care-cascade-in-the-bangladeshi-adult-population-a-nationally-representative-cross-sectional-study
#35
JOURNAL ARTICLE
Md Mostafa Monower, Shehab Uddin Al Abid, Ahmad Khairul Abrar, Sohel Reza Choudhury
OBJECTIVES: This study aimed to examine the distribution of daily salt intake across the hypertension care cascade and assess the proportional distribution of these care cascade categories across various salt consumption level. DESIGN: A population-based national cross-sectional study. SETTINGS: Data from the Bangladesh STEPS 2018 survey were used, encompassing both urban and rural strata within all eight divisions. National estimates were generated from weighted data...
April 5, 2024: BMJ Open
https://read.qxmd.com/read/38577884/life-science-2-0-reframing-the-life-science-sector-for-the-benefit-on-mankind
#36
JOURNAL ARTICLE
Michaela Vallin, Göran Tomson, Beate Kampmann, Eivind Engebretsen, Stefan Swartling Peterson, Rhoda K Wanyenze, Ole Petter Ottersen
The COVID-19 pandemic put the life science sector to the test. Vaccines were developed at unprecedented speed, benefiting from decades of fundamental research and now honoured by a Nobel Prize. However, we saw that the fruits of science were inequitably distributed. Most low- and middle-income countries were left behind, deepening the inequalities that the Sustainable Development Goals were set to reduce. We argue that the life science sector must reinvent itself to be better and more equitably prepared for the next health crisis and to ensure fair access to health across current and future generations...
December 31, 2024: Global Health Action
https://read.qxmd.com/read/38576522/cardiovascular-diseases-in-european-ethnic-minorities-beyond-the-traditional-cardiovascular-risk-factors
#37
EDITORIAL
Mohamed Bamoshmoosh
This editorial is intended to be a reflection on cardiovascular disease (CVD) burden in European ethnic minorities. In some European countries, ethnic minority realities, due to their recent appearance, are still to be studied in depth. The experience of several European countries, where the migration processes started earlier, even more than a century ago, can help by being an example. Many studies have shown that major differences in CVD burden exist not only between countries, but also within the same country when considering different social strata and ethnic groups...
March 26, 2024: World Journal of Cardiology
https://read.qxmd.com/read/38575937/low-long-lasting-insecticidal-net-use-in-malaria-elimination-areas-in-southern-ethiopia-results-from-community-based-cross-sectional-study
#38
JOURNAL ARTICLE
Misganu Endriyas, Mekidim Kassa, Yilma Chisha, Emebet Mekonnen, Tebeje Misganaw, Eskindir Loha, Ayalew Astatkie
BACKGROUND: Despite remarkable progress in malaria burden reduction, malaria continues to be a major public health problem globally. Ethiopia has been distributing long-lasting insecticidal nets (LLINs) for free and nationwide distribution was completed in 2016. However, evidence suggests that the utilization of LLINs varies from setting to setting and from time to time due to different factors, and up-to-date evidence is required for LLIN related decision-making. Hence, this study was designed to assess LLIN utilization and its determinants in the Southern Nations, Nationalities, and People's Region (SNNPR) of Ethiopia...
April 4, 2024: Malaria Journal
https://read.qxmd.com/read/38573760/leveraging-routinely-collected-program-data-to-inform-extrapolated-size-estimates-for-key-populations-in-namibia-small-area-estimation-study
#39
JOURNAL ARTICLE
Talia Loeb, Kalai Willis, Frans Velishavo, Daniel Lee, Amrita Rao, Stefan Baral, Katherine Rucinski
BACKGROUND: Estimating the size of key populations, including female sex workers (FSW) and men who have sex with men (MSM), can inform planning and resource allocation for HIV programs at local and national levels. In geographic areas where direct population size estimates (PSEs) for key populations have not been collected, small area estimation (SAE) can help fill in gaps using supplemental data sources known as auxiliary data. However, routinely collected program data have not historically been used as auxiliary data to generate subnational estimates for key populations, including in Namibia...
April 4, 2024: JMIR Public Health and Surveillance
https://read.qxmd.com/read/38571302/what-characteristics-are-most-important-in-stratifying-patients-into-groups-with-different-risk-of-diabetic-foot-ulceration
#40
JOURNAL ARTICLE
Roozbeh Naemi, Nachiappan Chockalingam, Janet K Lutale, Zulfiqarali G Abbas
AIMS/INTRODUCTION: This study aimed to assess if patients can be divided into different strata, and to explore if these correspond to the risk of diabetic foot complications. MATERIALS AND METHODS: A set of 28 demographic, vascular, neurological and biomechanical measures from 2,284 (1,310 men, 974 women) patients were included in this study. A two-step cluster analysis technique  was utilised to divide the patients into groups, each with similar characteristics...
April 3, 2024: Journal of Diabetes Investigation
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