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Medical management of kidney stones

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https://www.readbyqxmd.com/read/27856088/tolvaptan-and-kidney-pain-in-patients-with-autosomal-dominant%C3%A2-polycystic-kidney-disease-secondary-analysis-from%C3%A2-a-randomized-controlled-trial
#1
Niek F Casteleijn, Jaime D Blais, Arlene B Chapman, Frank S Czerwiec, Olivier Devuyst, Eiji Higashihara, Anna M Leliveld, John Ouyang, Ronald D Perrone, Vicente E Torres, Ron T Gansevoort
BACKGROUND: Kidney pain is a common complication in patients with autosomal dominant polycystic kidney disease (ADPKD), and data from the TEMPO 3:4 trial suggested that tolvaptan, a vasopressin V2 receptor antagonist, may have a positive effect on kidney pain in this patient group. Because pain is difficult to measure, the incidence of kidney pain leading to objective medical interventions was used in the present study to assess pain. STUDY DESIGN: Secondary analysis from a randomized controlled trial...
November 14, 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27834524/kidney-stones-pathophysiology-diagnosis-and-management
#2
Priscilla Cunningham, Helen Noble, Abdul-Kadhum Al-Modhefer, Ian Walsh
The prevalence of kidney stones is increasing, and approximately 12 000 hospital admissions every year are due to this condition. This article will use a case study to focus on a patient diagnosed with a calcium oxalate kidney stone. It will discuss the affected structures in relation to kidney stones and describe the pathology of the condition. Investigations for kidney stones, differential diagnosis and diagnosis, possible complications and prognosis, will be discussed. Finally, a detailed account of management strategies for the patient with kidney stones will be given, looking at pain management, medical procedures and dietary interventions...
November 10, 2016: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/27816709/urolithiasis-in-pregnancy
#3
REVIEW
Renato N Pedro, Krishanu Das, Noor Buchholz
Urolithiasis in pregnancy is a major health concern and can potentially affect the well-being of both mother and foetus. Management of this condition often entails simultaneous multidisciplinary involvement of obstetrician, radiologist and urologist. Additionally, adverse effects with usage of anaesthesia, radiation, medications and surgery on mother and foetus, limit utilisation of the full armamentarium of diagnostic and therapeutic modalities that are commonly used in non-pregnant women. This review was conducted using an electronic literature search of peer reviewed journal articles...
November 2, 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27733052/ultrasound-use-in-urinary-stones-adapting-old-technology-for-a-modern-day-disease
#4
David T Tzou, Manint Usawachintachit, Kazumi Taguchi, Thomas Chi
Ultrasound has become a mainstay tool in urologists' armamentarium for the diagnosis and management of nephrolithiasis. From starting as a rudimentary form of imaging, it has come to play a more prominent role over time, paralleling evolution in ultrasound technology. Throughout the medical community there is a growing emphasis on reducing the amount of ionizing radiation delivered to patients during routine imaging. As such there has been a resurgence of interest in ultrasound given its lack of associated radiation exposure and proven effectiveness as a diagnostic and therapeutic imaging modality...
October 12, 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27712954/2016-canadian-cardiovascular-society-guidelines-for-the-management-of-dyslipidemia-for-the-prevention-of-cardiovascular-disease-in-the-adult
#5
Todd J Anderson, Jean Grégoire, Glen J Pearson, Arden R Barry, Patrick Couture, Martin Dawes, Gordon A Francis, Jacques Genest, Steven Grover, Milan Gupta, Robert A Hegele, David C Lau, Lawrence A Leiter, Eva Lonn, G B John Mancini, Ruth McPherson, Daniel Ngui, Paul Poirier, John L Sievenpiper, James A Stone, George Thanassoulis, Richard Ward
Since the publication of the 2012 guidelines new literature has emerged to inform decision-making. The 2016 guidelines primary panel selected a number of clinically relevant questions and has produced updated recommendations, on the basis of important new findings. In subjects with clinical atherosclerosis, abdominal aortic aneurysm, most subjects with diabetes or chronic kidney disease, and those with low-density lipoprotein cholesterol ≥ 5 mmol/L, statin therapy is recommended. For all others, there is an emphasis on risk assessment linked to lipid determination to optimize decision-making...
July 25, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27649531/mechanistic-insights-into-the-antilithiatic-proteins-from-terminalia-arjuna-a-proteomic-approach-in-urolithiasis
#6
Amisha Mittal, Simran Tandon, Surender Kumar Singla, Chanderdeep Tandon
Kidney stone formation during hyperoxaluric condition is inherently dependent on the interaction between renal epithelial cells and calcium oxalate (CaOx) crystals. Although modern medicine has progressed in terms of removal of these stones, recurrence and persistent side effects restricts their use. Strategies involving plant based agents which could be used as adjunct therapy is an area which needs to be explored. Plant proteins having antilithiatic activity is a hitherto unexplored area and therefore, we conducted a detailed identification and characterization of antilithiatic proteins from Terminalia arjuna (T...
2016: PloS One
https://www.readbyqxmd.com/read/27593393/a-nurse-led-intervention-improves-detection-and-management-of-aki-in-malawi
#7
Christopher J Kirwan, Kelly Wright, Peter Banda, Aylwin Chick, Mwayi Mtekateka, Enos Banda, Zuze Kawale, Rhys Evans, Hamish Dobbie, Gavin Dreyer
BACKGROUND: Acute kidney injury is common and has significant impact on mortality and morbidity. There is a global drive to improve the lack of knowledge and understanding surrounding the recognition, diagnosis and management of patients with AKI in resource poor healthcare systems. OBJECTIVES: We propose a nurse-led education programme to medical and nursing staff of the Queen Elizabeth Central Hospital (QECH) in Blantyre, Malawi, will improve the overall care and understanding of patients with AKI that will still be effective 3 months later...
December 2016: Journal of Renal Care
https://www.readbyqxmd.com/read/27575503/pre-existing-renal-lesions-revealed-after-renal-trauma-difficulties-in-diagnosis-and-accountability-about-14-cases
#8
Sataa Sallami, Mohamed Mongi Mighri, Mahmoud Benatta, Hassen Khouni, Sana Abou El Makarim, Mohamed Allouch, Hassen Touinsi
OBJECTIVE: Pre-existing renal lesions (PERL) may interfere with the patho-physiology of trauma, alter the radiographic imaging and influence the therapeutic approach. The aims of this study were to record the PERL found incidentally during blunt renal trauma, to specify the place for effective conservative management and to determin the estimated partial permanent disability (PPD). PATIENTS AND METHODS: The medical records of 14 patients with PERL and blunt renal trauma were reviewed...
March 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/27459448/insights-into-nephrolithiasis-from-the-nurses-health-studies
#9
Megan L Prochaska, Eric N Taylor, Gary C Curhan
OBJECTIVES: To review the contributions of the Nurses' Health Study (NHS) I and NHS II to understanding the role of dietary factors, beverages, body size, and urinary factors in the development of kidney stones. METHODS: We conducted a review of kidney stone-related publications of NHS I and NHS II between 1976 and 2016. RESULTS: Studies using NHS I and NHS II data have demonstrated the importance of many factors in kidney stone formation and were the first to report that higher dietary calcium was associated with a lower risk of incident kidney stones in women...
September 2016: American Journal of Public Health
https://www.readbyqxmd.com/read/27349612/-nephrolithiasis-of-adult-from-mechanisms-to-preventive-medical-treatment
#10
M Courbebaisse, C Prot-Bertoye, J-P Bertocchio, S Baron, G Maruani, S Briand, M Daudon, P Houillier
Nephrolithiasis is a very common (prevalence around 10 to 12% in France) and recurrent disorder. Nephrolithiasis is associated to chronic kidney disease and is responsible for 2 to 3% of cases of end-stage renal disease, mainly if it is associated to nephrocalcinosis or to a monogenic disorder (1.6% of nephrolithiasis in adults, among them 1% of cystinuria). To understand the underlying pathophysiological processes, stone analysis (morphology and using infrared spectrophotometry) as well as minimal biological assessment including urine crystal research are required...
June 24, 2016: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/27123330/a-snapshot-of-the-adult-spina-bifida-patient-high-incidence-of-urologic-procedures
#11
Joceline S Liu, Alyssa Greiman, Jessica T Casey, Shubhra Mukherjee, Stephanie J Kielb
INTRODUCTION: To describe the urologic outcomes of contemporary adult spina bifida patients managed in a multidisciplinary clinic. MATERIAL AND METHODS: A retrospective chart review of patients seen in our adult spina bifida clinic from January 2004 to November 2011 was performed to identify urologic management, urologic surgeries, and co-morbidities. RESULTS: 225 patients were identified (57.8% female, 42.2% male). Current median age was 30 years (IQR 27, 36) with a median age at first visit of 25 years (IQR 22, 30)...
2016: Central European Journal of Urology
https://www.readbyqxmd.com/read/27080725/how-do-urinary-calculi-influence-health-related-quality-of-life-and-patient-treatment-preference-a-systematic-review
#12
Aditya Raja, Zara Hekmati, Hrishi B Joshi
INTRODUCTION: Urinary stone disease is a common and often recurrent condition that can affect kidney function and requires a range of medical and surgical treatments, all of which can have a significant impact on patients' health-related quality of life (HRQoL) and treatment preferences. OBJECTIVE: To review the literature systematically for all studies that include HRQoL measurement or patient preferences in the context of urinary stone disease. METHODS: Ovid MEDLINE(R), Ovid MEDLINE(R) In-Process, EMBASE, SCOPUS, EconLit, and Web of Science were searched from inception to January 2016...
July 2016: Journal of Endourology
https://www.readbyqxmd.com/read/27032222/managing-acute-and-chronic-renal-stone-disease
#13
REVIEW
Conor P Moran, Aisling E Courtney
Nephrolithiasis, or renal stone disease, is common and the incidence is increasing globally. In the UK the lifetime risk is estimated to be 8-10%. On a population level, the increase in stone incidence, erosion of gender disparity, and younger age of onset is likely to reflect increasing prevalence of obesity and a Western diet with a high intake of animal protein and salt. Stones can be detected by a variety of imaging techniques. The gold standard is a non-contrast CT of kidneys, ureters and bladder (CT KUB) which can identify > 99% of stones...
February 2016: Practitioner
https://www.readbyqxmd.com/read/26977089/medical-management-of-renal-stones
#14
REVIEW
Monica S C Morgan, Margaret S Pearle
The prevalence of kidney stones is increasing in industrialized nations, resulting in a corresponding rise in economic burden. Nephrolithiasis is now recognized as both a chronic and systemic condition, which further underscores the impact of the disease. Diet and environment play an important role in stone disease, presumably by modulating urine composition. Dietary modification as a preventive treatment to decrease lithogenic risk factors and prevent stone recurrence has gained interest because of its potential to be safer and more economical than drug treatment...
March 14, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/26966587/silodosin-vs-tamsulosin-in-the-management-of-distal-ureteric-stones-a-prospective-randomised-study
#15
Hazem Elgalaly, Ahmed Sakr, Amr Fawzi, Emad A Salem, Esam Desoky, Ashraf Shahin, Mostafa Kamel
OBJECTIVES: To compare the efficacy of silodosin (8 mg) vs tamsulosin (0.4 mg), as a medical expulsive therapy, in the management of distal ureteric stones (DUS) in terms of stone clearance rate and stone expulsion time. PATIENTS AND METHODS: A prospective randomised study was conducted on 115 patients, aged 21-55 years, who had unilateral DUS of ⩽10 mm. Patients were divided into two groups. Group 1 received silodosin (8 mg) and Group 2 received tamsulosin (0...
March 2016: Arab Journal of Urology
https://www.readbyqxmd.com/read/26874536/evolving-guidance-on-ureteric-calculi-management-in-the-acute-setting
#16
REVIEW
Jonathan K Makanjuola, Sophie Rintoul-Hoad, Matthew Bultitude
Ureteric colic is a common presentation to acute emergency services. The gold standard test for the diagnosis of acute ureteric colic is a non-contrast computer tomography of the kidneys ureters and bladder (CT KUB). Non-steroidal anti-inflammatory drugs (NSAIDs) should be used as first-line analgesia, with studies showing that there is no role for steroid or phosphodiesterase-5 inhibitors. There is emerging evidence that a high body mass index (BMI) is a risk factor. The drugs used to facilitate stone passage are known as medical expulsive therapy (MET)...
March 2016: Current Urology Reports
https://www.readbyqxmd.com/read/26864746/preliminary-evidence-of-decreased-disease-specific-health-related-quality-of-life-in-asymptomatic-stone-patients
#17
Kristina L Penniston, Brian C Sninsky, Stephen Y Nakada
INTRODUCTION: Kidney stone patients have lower health-related quality of life (HRQOL) than nonstone formers. Among active stone patients (those with stones), those with symptoms have lower HRQOL than those without. However, little is known about whether asymptomatic stones affect patients' HRQOL. METHODS: A sample of asymptomatic stone formers was assembled by identifying patients who reported no symptoms on the disease-specific Wisconsin Stone Quality of Life (WiSQoL) questionnaire (n=351)...
May 2016: Journal of Endourology
https://www.readbyqxmd.com/read/26579264/shock-wave-lithotripsy-in-the-elderly-safety-efficacy-and-special-considerations
#18
Prodromos Philippou, D Lamrani, Konstantinos Moraitis, Hassan Wazait, Junaid Masood, Noor Buchholz
PURPOSE: Shock-wave lithotripsy (SWL) for elderly patients can be challenging. Patients often have a long-standing complex stone burden and significant comorbidities. We report a cohort of patients aged ⩾70 years who were treated by SWL, with special attention to treatment outcomes, complications and the need for adjuvant procedures. PATIENTS AND METHODS: Over a period of 4 years, 2311 patients were treated with SWL in a tertiary referral centre. Among these patients, 137 were aged ⩾70 years (5...
March 2011: Arab Journal of Urology
https://www.readbyqxmd.com/read/26530696/-diagnosis-and-treatment-of-nephrolithiasis-what-is-established
#19
REVIEW
A Pfau, K-U Eckardt, F Knauf
BACKGROUND: Kidney stones are a common and increasing problem worldwide. Nephrolithiasis is frequently a chronic disease given the risk of recurrence following passage of a first stone. OBJECTIVES: In the present article, an update on the diagnosis and treatment of kidney stones relevant for internal medicine physicians is provided. METHODS: This review is based on a selective literature search and our own work. RESULTS AND CONCLUSION: The diagnosis of kidney stones is based on the clinical history and physical examination...
December 2015: Der Internist
https://www.readbyqxmd.com/read/26512768/an-overview-of-normocalcemic-primary-hyperparathyroidism
#20
REVIEW
Monika Pawlowska, Natalie E Cusano
PURPOSE OF REVIEW: Normocalcemic primary hyperparathyroidism (PHPT) received special attention in the publication of the conference proceedings from the Fourth International Workshop on the Management of Asymptomatic PHPT, although much remains unknown about the disorder. RECENT FINDINGS: Observational studies have found that despite maintaining normocalcemia, patients with normocalcemic PHPT have a high incidence of kidney stones and osteoporosis. Small studies focusing on the cardiovascular implications of normocalcemic PHPT have shown a possible association with hypertension and an atherogenic lipid profile, but not insulin resistance...
December 2015: Current Opinion in Endocrinology, Diabetes, and Obesity
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