keyword
MENU ▼
Read by QxMD icon Read
search

Current controversies in Psychiatry

keyword
https://www.readbyqxmd.com/read/29045768/a-brief-history-of-lithium-treatment-in-psychiatry
#1
Mark L Ruffalo
The history of lithium as a psychiatric medication is marked by its serendipitous discovery, its lengthy path to US Food and Drug Administration approval, and controversy surrounding its current status in bipolar disorder treatment. Without doubt, the discovery of lithium as a psychotropic agent forever changed the course of psychiatry. The drug's fascinating, and sometimes contentious, history is reviewed here.
October 12, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/28944628/-understanding-the-use-of-mechanical-restraints-in-psychiatry-phenomenological-study-of-nurses%C3%A2-lived-experience
#2
Pascale Corneau, Jean Daniel Jacob, Dave Holmes, Desire Rioux
The use of mechanical restraints in psychiatric settings is currently the subject of ethical controversy. However, both patients' and nurses' voices are absent in the debate over this controversial intervention. The objective of this qualitative study was to examine the experience of psychiatric nurses using mechanical restraints. Twentyone nurses working on either the acute psychiatric inpatient unit and/or the emergency psychiatric unit of a university affiliated Canadian hospital participated in semi-structured interviews, which were then transcribed, coded and analyzed using the interpretative phenomenological analysis (IPA) method...
April 19, 2017: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/28485405/investigating-the-neuroimmunogenic-architecture-of-schizophrenia
#3
R Birnbaum, A E Jaffe, Q Chen, J H Shin, J E Kleinman, T M Hyde, D R Weinberger
The role of the immune system in schizophrenia remains controversial despite numerous studies to date. Most studies have profiled expression of select genes or proteins in peripheral blood, but none have focused on the expression of canonical pathways that mediate overall immune response. The current study used a systematic genetic approach to investigate the role of the immune system in a large sample of post-mortem brain of patients with schizophrenia: RNA sequencing was performed to assess the differential expression of 561 immune genes and 20 immune pathways in dorsolateral prefrontal cortex (DLPFC) (144 schizophrenia and 196 control subjects) and hippocampus (83 schizophrenia and 187 control subjects)...
May 9, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28477247/why-psychiatry-needs-3-4-methylenedioxymethamphetamine-a-child-psychiatrist-s-perspective
#4
REVIEW
Ben Sessa
Since the late 1980s the psychoactive drug 3,4-methylenedioxymethamphetamine (MDMA) has had a well-known history as the recreationally used drug ecstasy. What is less well known by the public is that MDMA started its life as a therapeutic agent and that in recent years an increasing amount of clinical research has been undertaken to revisit the drug's medical potential. MDMA has unique pharmacological properties that translate well to its proposed agent to assist trauma-focused psychotherapy. Psychological trauma-especially that which arises early in life from child abuse-underpins many chronic adult mental disorders, including addictions...
July 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/28445399/advances-in-psychiatric-diagnosis-past-present-and-future
#5
EDITORIAL
Carol S North, Alina M Surís
This editorial examines controversies identified by the articles in this special issue, which explore psychopathology in the broad history of the classification of selected psychiatric disorders and syndromes over time through current American criteria. Psychiatric diagnosis has a long history of scientific investigation and application, with periods of rapid change, instability, and heated controversy associated with it. The articles in this issue examine the history of psychiatric nomenclature and explore current and future directions in psychiatric diagnosis through the various versions of accepted diagnostic criteria and accompanying research literature addressing the criteria...
April 26, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28373794/evaluation-of-oxidative-stress-in-bipolar-disorder-in-terms-of-total-oxidant-status-total-antioxidant-status-and-oxidative-stress-index
#6
Merve Cingi Yirün, Kübranur Ünal, Neslihan Altunsoy Şen, Onur Yirün, Çiğdem Aydemir, Erol Göka
INTRODUCTION: Bipolar disorder is one of the most debilitating psychiatric disorders characterized by disruptive episodes of mania/hypomania and depression. Considering the complex role of biological and environmental factors in the etiology of affective disorders, recent studies have focused on oxidative stress, which may damage nerve cell components and take part in pathophysiology. The aim of the present study was to contribute to the data about oxidative stress in bipolar disorder by detecting the total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) levels of manic episode (ME) and euthymic (EU) patients and by comparing these results with those of healthy controls (HCs)...
September 2016: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28373689/collaborative-meta-analysis-finds-no-evidence-of-a-strong-interaction-between-stress-and-5-httlpr-genotype-contributing-to-the-development-of-depression
#7
R C Culverhouse, N L Saccone, A C Horton, Y Ma, K J Anstey, T Banaschewski, M Burmeister, S Cohen-Woods, B Etain, H L Fisher, N Goldman, S Guillaume, J Horwood, G Juhasz, K J Lester, L Mandelli, C M Middeldorp, E Olié, S Villafuerte, T M Air, R Araya, L Bowes, R Burns, E M Byrne, C Coffey, W L Coventry, K A B Gawronski, D Glei, A Hatzimanolis, J-J Hottenga, I Jaussent, C Jawahar, C Jennen-Steinmetz, J R Kramer, M Lajnef, K Little, H M Zu Schwabedissen, M Nauck, E Nederhof, P Petschner, W J Peyrot, C Schwahn, G Sinnamon, D Stacey, Y Tian, C Toben, S Van der Auwera, N Wainwright, J-C Wang, G Willemsen, I M Anderson, V Arolt, C Åslund, G Bagdy, B T Baune, F Bellivier, D I Boomsma, P Courtet, U Dannlowski, E J C de Geus, J F W Deakin, S Easteal, T Eley, D M Fergusson, A M Goate, X Gonda, H J Grabe, C Holzman, E O Johnson, M Kennedy, M Laucht, N G Martin, M R Munafò, K W Nilsson, A J Oldehinkel, C A Olsson, J Ormel, C Otte, G C Patton, B W J H Penninx, K Ritchie, M Sarchiapone, J M Scheid, A Serretti, J H Smit, N C Stefanis, P G Surtees, H Völzke, M Weinstein, M Whooley, J I Nurnberger, N Breslau, L J Bierut
The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is associated with increased risk of depression, but only in individuals exposed to stressful situations, has generated much interest, research and controversy since first proposed in 2003. Multiple meta-analyses combining results from heterogeneous analyses have not settled the issue. To determine the magnitude of the interaction and the conditions under which it might be observed, we performed new analyses on 31 data sets containing 38 802 European ancestry subjects genotyped for 5-HTTLPR and assessed for depression and childhood maltreatment or other stressful life events, and meta-analysed the results...
April 4, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28033511/vitamin-d-and-alcohol-a-review-of-the-current-literature
#8
REVIEW
Vitor Soares Tardelli, Mariana Pimentel Pádua do Lago, Dartiu Xavier da Silveira, Thiago Marques Fidalgo
Vitamin D is associated with bone mineral density, and its deficiency is a global health problem. In psychiatry, low vitamin D levels have been associated with schizophrenia, depression, psychotic symptoms, and, more recently, alcohol use disorders. Alcohol use disorders are among the most prevalent mental disorders worldwide. Therefore, our aim was to evaluate the association between alcohol use and vitamin D serum levels. The PubMed, SCIELO, and Lilacs databases were searched for this systematic review. We assessed all articles published from 1976 to December 2015, and we examined the associated reference lists to retrieve articles that appeared to fulfill our criteria...
February 2017: Psychiatry Research
https://www.readbyqxmd.com/read/27791968/the-whole-versus-the-sum-of-some-of-the-parts-toward-resolving-the-apparent-controversy-of-clitoral-versus-vaginal-orgasms
#9
James G Pfaus, Gonzalo R Quintana, Conall Mac Cionnaith, Mayte Parada
BACKGROUND: The nature of a woman's orgasm has been a source of scientific, political, and cultural debate for over a century. Since the Victorian era, the pendulum has swung from the vagina to the clitoris, and to some extent back again, with the current debate stuck over whether internal sensory structures exist in the vagina that could account for orgasms based largely on their stimulation, or whether stimulation of the external glans clitoris is always necessary for orgasm. METHOD: We review the history of the clitoral versus vaginal orgasm debate as it has evolved with conflicting ideas and data from psychiatry and psychoanalysis, epidemiology, evolutionary theory, feminist political theory, physiology, and finally neuroscience...
2016: Socioaffective Neuroscience & Psychology
https://www.readbyqxmd.com/read/27514542/how-valid-is-placebo-in-the-indian-setting
#10
Himanshu Sharma, Bharti Sharma
BACKGROUND: The Placebo is defined as an inert substance with a potent therapeutic effect. Its effect is attributed to its psychological and neurobiological effect. Its use in Psychiatric drug practice, drug trials and clinical practice is common, especially in India. Currently there is a debate whether to use it or not as there are ethical, moral and legal issues. Also, its mechanism of action is not known. DISCUSSION: The Indian Psychiatry scenario is muddled in relation to use of placebo in Randomized Controlled Trials or Psychiatric clinical practice...
2017: Central Nervous System Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/27271002/theory-of-mind-and-verstehen-understanding-methodology
#11
REVIEW
Tsutomu Kumazaki
Theory of mind is a prominent, but highly controversial, field in psychology, psychiatry, and philosophy of mind. Simulation theory, theory-theory and other views have been presented in recent decades, none of which are monolithic. In this article, various views on theory of mind are reviewed, and methodological problems within each view are investigated. The relationship between simulation theory and Verstehen (understanding) methodology in traditional human sciences is an intriguing issue, although the latter is not a direct ancestor of the former...
September 2016: History of Psychiatry
https://www.readbyqxmd.com/read/26650560/-debating-psychiatry-a-critical-review-of-some-recent-discussions
#12
Elena Levy Yeyati
This paper reviews the principal critiques and reactions stated regarding the launching of DSM-5 up to the present days in Anglo-Saxon's mental health domain. The arguments are gathered as follows: current diagnoses systems; validity of psychiatric diagnoses; limits of the efficacy of psychiatric treatments (especially medications and conflict of interests); the image of psychiatry in user's networks. In the end controversies get polarized between medicalization of ordinary life and antipsychiatry. However, if acknowledged impasses and benevolent distrust are tolerated, it is possible to make a clinical use of the critiques and reactions...
May 2015: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/26552314/-changing-forensic-mental-health-in-france-a-review
#13
REVIEW
Yoji Nakatani, Suguru Hasuzawa
This article describes the background and recent changes in French forensic mental health. The literature suggests that three law reforms have been crucial to changes in the mental health system. First, the Penal Code of 1992 redefined the provisions of criminal responsibility and introduced the category of diminished responsibility. Second, a controversial law for preventive detention (rétention de sûretê) was enacted in 2008, according to which criminals with severe personality disorders are subject to incarceration even after the completion of their prison sentences if they are still considered to pose a danger to the public...
2015: Seishin Shinkeigaku Zasshi, Psychiatria et Neurologia Japonica
https://www.readbyqxmd.com/read/26424419/dysregulation-of-the-nf-%C3%AE%C2%BAb-pathway-as-a-potential-inducer-of-bipolar-disorder
#14
REVIEW
Eran Elhaik, Peter Zandi
A century of investigations enhanced our understanding of bipolar disorder although it remains a complex multifactorial disorder with a mostly unknown pathophysiology and etiology. The role of the immune system in this disorder is one of the most controversial topics in genetic psychiatry. Though inflammation has been consistently reported in bipolar patients, it remains unclear how the immunologic process influences the disorder. One of the core components of the immune system is the NF-κB pathway, which plays an essential role in the development of innate and adaptive immunity...
November 2015: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/26402895/-a-balanced-perspective-on-psychiatric-classification
#15
A S G Ralston, J A Swinkels
BACKGROUND: Professional journals in the Dutch language have played hardly any part in the recent controversies relating to DSM-5. So far, there has been no philosophical analysis of these discussions. AIM: To discuss the current philosophical and psychiatric literature pertaining to the current debate on psychiatric classification. Our main focus will be on a scientific and realistic approach to classification. METHOD: We discuss the literature from historical, scientific and philosophical perspectives...
2015: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/26099166/research-review-use-of-eeg-biomarkers-in-child-psychiatry-research-current-state-and-future-directions
#16
Sandra K Loo, Agatha Lenartowicz, Scott Makeig
BACKGROUND: Electroencephalography (EEG) and related measures have a long and productive history in child psychopathology research and are currently experiencing a renaissance in interest, particularly for use as putative biomarkers. METHOD AND SCOPE: First, the recent history leading to the use of EEG measures as endophenotypes and biomarkers for disease and treatment response are reviewed. Two key controversies within the area of noninvasive human electrophysiology research are discussed, and problems that currently either function as barriers or provide gateways to progress...
June 23, 2015: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/26081322/-the-search-of-the-intact-structural-and-functional-brain-systems-as-a-paradigm-shift-in-schizophrenia-research
#17
I S Lebedeva
OBJECTIVE: The search of the structural and functional brain characteristics is one of the most studied directions in the modern biological psychiatry. However, in spite of the numerous studies the results are still controversial. As the necessity of the shift of the current paradigm in schizophrenia research evolves it has been suggested to discriminate not only abnormal but stable functioning neuronal circuits as well. Consequently, the aim is formulated as the search of the minimal brain damage sufficient for disease development...
2015: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/25880379/from-dsm-i-to-dsm-5
#18
EDITORIAL
Vassilis Kontaxakis, George Konstantakopoulos
No abstract text is available yet for this article.
January 2015: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/25589126/-seclusion-in-emergency-psychiatry
#19
Reidun Norvoll, Torleif Ruud, Torfinn Hynnekleiv
BACKGROUND: In Norway, seclusion (also called «shielding» or «open-area seclusion») is often used as an intervention in inpatient psychiatric wards as a continuation of milieu therapy, but the method remains controversial in health policy. A psychiatrist or occasionally a psychologist is responsible for making a decision on seclusion pursuant to Section 4-3 of the Mental Health Care Act. Because of the uncertainty regarding the content and academic legitimacy of this model, we have undertaken a review of available literature on the justification, practical application and effect of the Norwegian tradition of seclusion...
January 13, 2015: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
https://www.readbyqxmd.com/read/25546645/-are-we-child-psychiatrists-pathologizing-childhood
#20
Gabriel Kunst
Child psychiatry is a young discipline with great potential. Comparing the current resources that we had a few decades ago the contrast is marked. Our discipline has had a great development. The current psychiatric thinking cannot be defined based on one main theory to which all psychiatrists adhere. There is a theoretical pluralism where different models coexist in tension. The child psychiatrist requires conducting diagnostic regardless of their frame of reference without polarizing the field because not only is required to make a psychiatric diagnosis but also requires an understanding of the unique problems of the patient...
July 2014: Vertex: Revista Argentina de Psiquiatriá
keyword
keyword
8952
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"