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Colon diverticulosis

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https://www.readbyqxmd.com/read/28079347/the-diagnostic-challenge-of-symptomatic-uncomplicated-diverticular-disease
#1
Cesare Cremon, Lara Bellacosa, Maria R Barbaro, Rosanna F Cogliandro, Vincenzo Stanghellini, Giovanni Barbara
Colonic diverticulosis is a common condition in Western industrialized countries occurring in up to 65% of people over the age of 60 years. Only a minority of these subjects (about 10- 25%) experience symptoms, fulfilling Rome criteria for irritable bowel syndrome (IBS) diagnosis (IBS-like symptoms) in 10 to 66% of cases. Symptomatic uncomplicated diverticular disease (SUDD) is a syndrome characterized by recurrent abdominal symptoms attributed to diverticula in the absence of macroscopically evident alterations other than the presence of diverticula...
January 12, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28045757/left-colonic-bleeding-secondary-to-inferior-mesenteric-vein-stenosis
#2
Thang Q Le, Donald Romanelli
Lower gastrointestinal bleeding is most commonly associated with diverticulosis, ischemic colitis, vascular ectasia, and anorectal disease and less commonly associated with colonic malignancy. Infrequently, it is associated with mesenteric varices, a rare etiology that is not well documented in the radiology literature. We present a case of a 50-year-old man diagnosed as having intermittent left colonic bleeding from mesenteric varices due to a critical stenosis at the portal vein-inferior mesenteric vein confluence...
December 29, 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27994893/cholecystocolonic-fistulas-from-diverticulosis-a-potentially-missable-cause-of-liver-abscesses
#3
Ben Warner, Terry Wong, Philip Berry
Cholecystocolonic fistulas (CCF) due to colonic diverticulosis are a rare cause of liver abscesses. It is even rarer to simultaneously have choledocholithiasis, another cause for liver abscesses. In this case report, we found both pathologies and emphasise the need to study cholangiograms carefully so as not to miss alternative diagnoses.
2016: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/27973464/pathogenesis-of-diverticulosis-and-diverticular-disease
#4
Marjorie M Walker, Angela K Harris
Diverticulosis is defined by the presence of diverticula due to herniation of mucosa and muscularis mucosa through the muscularis propria at sites of vascular penetration in the colon and is asymptomatic in the vast majority affected. There are global differences of distribution, in Western industrialised societies, the most common site is in the right colon, but in Asia left sided diverticulosis predominates. Whilst present in 17.5% of a general population and 42% of all comers at endoscopy it is seen in 71% of those aged ≥80 years...
December 14, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27920469/role-of-ultrasound-in-colorectal-diseases
#5
REVIEW
Renáta Bor, Anna Fábián, Zoltán Szepes
Ultrasound is an undervalued non-invasive examination in the diagnosis of colonic diseases. It has been replaced by the considerably more expensive magnetic resonance imaging and computed tomography, despite the fact that, as first examination, it can usefully supplement the diagnostic process. Transabdominal ultrasound can provide quick information about bowel status and help in the choice of adequate further examinations and treatment. Ultrasonography, as a screening imaging modality in asymptomatic patients can identify several colonic diseases such as diverticulosis, inflammatory bowel disease or cancer...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27815648/small-bowel-diverticulitis-an-imaging-review-of-an-uncommon-entity
#6
Darren L Transue, Tarek N Hanna, Haris Shekhani, Saurabh Rohatgi, Faisal Khosa, Jamlik-Omari Johnson
In this review, we discuss the clinical and radiologic findings of small bowel diverticulosis, which is infrequently encountered during practice and far less common than colonic diverticulosis. Small bowel diverticulosis can present with a range of emergent symptomatic complications including diverticulitis, perforation, or hemorrhage. Here, we focus on the clinical features, pathogenesis, radiologic findings, and treatment of small bowel diverticulitis. Although not routinely considered in the differential diagnosis of an acute abdomen, prospective radiologic diagnosis of small bowel diverticulitis is important and can lead to conservative treatment thus preventing unnecessary exploratory laparotomy...
November 4, 2016: Emergency Radiology
https://www.readbyqxmd.com/read/27763879/a-prospective-descriptive-study-to-assess-the-effect-of-dietary-and-pharmacological-strategies-to-manage-constipation-in-patients-with-a-stoma
#7
Lukasz Krokowicz, Adam Bobkiewicz, Maciej Borejsza-Wysocki, Barbara Kuczynska, Aleksandra Lisowska, Urszula Skowronska-Piekarska, Jacek Paszkowski, Jaroslaw Walkowiak, Michal Drews, Tomasz Banasiewicz
The term constipation with regard to patients with a stoma is defined as impaired bowel movements associated with increased stool consistency or long periods without bowel movements that lead to discomfort, flatulence, and abdominal pain. Information about constipation in patients with a stoma is limited. A prospective, descriptive study was conducted among patients attending ostomy and proctology outpatient clinics in Poznan, Poland between January 2011 and December 2014 to assess the role of dietary and pharmacological strategies in the management of constipation in patients with a stoma...
December 2015: Ostomy/wound Management
https://www.readbyqxmd.com/read/27762218/coloenteric-fistula-in-a-young-patient-with-recurrent-diverticulitis-a-case-report-and-review-of-the-literature
#8
D S Ahmad, E E Quist, G F Hutchins, I Bhat
The development of colonic diverticula is common in developed countries and complications of colonic diverticulosis are responsible for a remarkable burden of the disease. The natural history and management of complicated and recurrent diverticulitis in young patients are still a matter of debate. Coloenteric fistula is a rare complication of diverticulitis in young adults. In this report, and utilising a case study, we will review the natural history, outcome and management of acute diverticulitis in the young...
October 2016: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/27741164/probiotics-and-diverticular-disease-evidence-based
#9
Edith Lahner, Bruno Annibale
Diverticular disease (DD) is a common gastrointestinal condition. Clinical spectrum ranges from asymptomatic diverticulosis to symptomatic uncomplicated or complicated DD. Symptoms related to uncomplicated DD are not specific and may be indistinguishable from those of irritable bowel syndrome. Low-grade inflammation, altered intestinal microbiota, visceral hypersensitivity, and abnormal colonic motility have been identified as factors potentially contributing to symptoms. Probiotics may modify the gut microbial balance leading to health benefits...
November 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27688648/segmental-colitis-associated-diverticulosis-syndrome
#10
EDITORIAL
Hugh J Freeman
Segmental colitis associated diverticulosis (SCAD) has become increasingly appreciated as a form of inflammatory disease of the colon. Several features suggest that SCAD is a distinct disorder. SCAD tends to develop almost exclusively in older adults, predominately, but not exclusively, males. The inflammatory process occurs mainly in the sigmoid colon, and usually remains localized to this region of the colon alone. SCAD most often presents with rectal bleeding and subsequent endoscopic visualization reveals a well localized process with non-specific histopathologic inflammatory changes...
September 28, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27622380/current-management-of-patients-with-diverticulosis-and-diverticular-disease-a-survey-from-the-2nd-international-symposium-on-diverticular-disease
#11
Antonio Tursi, Marcello Picchio, Walter Elisei, Francesco Di Mario, Carmelo Scarpignato, Giovanni Brandimarte
BACKGROUND: Management of diverticular disease (DD) remains a point of debate. GOALS: To investigate the current opinion of participants of the 2nd International Symposium on Diverticular Disease, on real-life management of patients with DD of the colon. STUDY: Twelve questions were aimed at the diagnosis, treatment, and management options for diverticulosis and symptomatic DD. RESULTS: In total, 115 surveys from 8 European Countries were filled out...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27622378/assessment-of-fecal-microbiota-and-fecal-metabolome-in-symptomatic-uncomplicated-diverticular-disease-of-the-colon
#12
Antonio Tursi, Paola Mastromarino, Daniela Capobianco, Walter Elisei, Alfredo Miccheli, Giorgio Capuani, Alberta Tomassini, Giuseppe Campagna, Marcello Picchio, GianMarco Giorgetti, Federica Fabiocchi, Giovanni Brandimarte
GOAL: The aim of this study was to assess fecal microbiota and metabolome in a population with symptomatic uncomplicated diverticular disease (SUDD). BACKGROUND: Whether intestinal microbiota and metabolic profiling may be altered in patients with SUDD is unknown. PATIENTS AND METHODS: Stool samples from 44 consecutive women [15 patients with SUDD, 13 with asymptomatic diverticulosis (AD), and 16 healthy controls (HCs)] were analyzed. Real-time polymerase chain reaction was used to quantify targeted microorganisms...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27622377/the-management-of-patients-with-diverticulosis-and-diverticular-disease-in-primary-care-an-online-survey-among-italian-general-pratictioners
#13
Rudi De Bastiani, Guido Sanna, Pierluigi Fracasso, Maurizio D'Urso, Edoardo Benedetto, Antonio Tursi
GOALS: To investigate the current opinion of Italian general practitioners (GPs) on the management of patients with diverticular disease (DD) of the colon. BACKGROUND: The management of DD remains a point of debate, and guidelines are not uniform in their advice. STUDY: A web-based survey was conducted among Italian GPs. Twelve questions were aimed at the diagnosis, treatment, and management options for diverticulosis and symptomatic DD. RESULTS: In total, 245 surveys were filled out...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27622371/probiotics-for-the-treatment-of-symptomatic-uncomplicated-diverticular-disease-rationale-and-current-evidence
#14
Carmelo Scarpignato, Anna Bertelé, Antonio Tursi
Changes in the colonic microbiota are critical to the pathogenesis of diverticular complications such as diverticulitis and peridiverticular abscesses. However, more subtle changes in microbiota composition may well be important to the more chronic manifestations of diverticulosis. Some studies have shown the presence of bacterial overgrowth in subgroups of patients with diverticular disease and recent studies, using molecular biology techniques, found an increase of proteobacteria and actinobacteria in patients with symptomatic uncomplicated diverticular disease (SUDD), compared with healthy controls...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27622369/treatment-of-diverticular-disease-with-aminosalicylates-the-evidence
#15
Giovanni Barbara, Cesare Cremon, Maria R Barbaro, Lara Bellacosa, Vincenzo Stanghellini
Colonic diverticulosis is an increasingly common condition in Western industrialized countries. About 20% of patients develop symptoms, including abdominal pain, bloating, changes in bowel habits, and, eventually, diverticulitis or other complications. The management of symptomatic uncomplicated diverticular disease (SUDD) and the prevention of acute diverticulitis remains a challenge for the clinician. The rationale for the use of aminosalicylates, such as mesalazine, is based on the assumption of low-grade inflammation in SUDD and symptoms generation, whereas an overt inflammation may induce diverticulitis in patients with diverticular disease...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27622359/how-to-differentiate-segmental-colitis-associated-with-diverticulosis-and-inflammatory-bowel-diseases
#16
Claudio Cassieri, Giovanni Brandimarte, Walter Elisei, Giuseppina P Lecca, Elisabetta Goni, Antonio Penna, Marcello Picchio, Antonio Tursi
The segmental colitis associated with diverticulosis," better known by its acronym "SCAD," is a chronic inflammatory process localized in the colonic area presenting diverticulosis, and therefore mainly in the sigmoid colon. By definition, both the rectum and the right colon are spared from any inflammation both endoscopically and from a histologic point of view. Recent data have hypothesized that SCAD may be an independent clinical entity within the inflammatory bowel disease set of diseases. Compared with inflammatory bowel disease, SCAD seems to have a more benign outcome, with low rate of complications...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27622358/prevalence-of-colonic-diverticulosis-in-patients-affected-by-ulcerative-colitis-a-prospective-study
#17
Claudio Cassieri, Roberta Pica, Eleonora V Avallone, Maddalena Zippi, Pietro Crispino, Daniela De Nitto, Paolo Paoluzi, Giovanni Brandimarte, Piera Giuseppina Lecca, Walter Elisei, Marcello Picchio, Antonio Tursi
BACKGROUND: Diverticulosis of the colon is an acquired condition that results from herniation of the mucosa and submucosa through defects in the muscular layer. The true prevalence of colonic diverticulosis is difficult to measure because most individuals are asymptomatic. In particularly, in literature, there are few studies about the prevalence of colonic diverticulosis in patients affected by ulcerative colitis (UC). GOALS: To investigate the prevalence of colonic diverticulosis in UC and in adult patients referred in a single center...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27622356/the-role-of-biomarkers-in-diverticular-disease
#18
Antonella Gallo, Gianluca Ianiro, Massimo Montalto, Giovanni Cammarota
Diverticulosis of the colon is a common condition in western countries. Acute diverticulitis may occur in 10% to 25% of the patients, sometimes associated with the presence of complications such as abscess, fistula, and perforation. Early diagnosis and accurate assessment of acute diverticulitis are necessary to start an efficacious treatment promptly, either conservatively or by surgery. The clinical picture may mimic other abdominal conditions; therefore, imaging techniques such as ultrasound or computed tomography are usually recommended, although they are expensive, examiner dependent, and potentially harmful...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27622355/diverticular-disease-of-the-colon-news-from-imaging
#19
Nicola Flor, Simone Soldi, Edoardo Zanchetta, Sara Sbaraini, Filippo Pesapane
Different scenarios embrace computed tomography imaging and diverticula, including asymptomatic (diverticulosis) and symptomatic patients (acute diverticulitis, follow-up of acute diverticulitis, chronic diverticulitis). If the role of computed tomography is validated and widely supported by evidence in case of acute diverticulitis, this is not the case of patients in their follow-up for acute diverticulitis or with symptoms related to diverticula, but without acute inflammation. In these settings, computed tomography colonography is gaining consensus as the preferred radiologic test...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27622352/prognostic-role-of-the-endoscopic-classification-dica
#20
Antonio Tursi, Giovanni Brandimarte, Francesco Di Mario, Walter Elisei, Carmelo Scarpignato, Marcello Picchio
Diverticular inflammation and complication assessment (DICA) endoscopic classification has been recently developed for patients suffering from diverticulosis and diverticular disease. Its predictive value in those patients was recently retrospectively assessed. For each patient, the following parameters were recorded: age, severity of DICA, presence of abdominal pain, C-reactive protein, fecal calprotectin test (if available) at the time of diagnosis, months of follow-up, therapy taken during the follow-up to maintain remission (if any), occurrence/recurrence of diverticulitis, and need of surgery...
October 2016: Journal of Clinical Gastroenterology
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