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Colon diverticulosis

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https://www.readbyqxmd.com/read/28932890/the-correlation-between-diverticulosis-and-redundant-colon
#1
Tahleesa Cuda, Ronny Gunnarsson, Alan de Costa
BACKGROUND: Diverticulosis and redundant colon are colonic conditions for which underlying pathophysiology, management and prevention are poorly understood. Historical papers suggest an inverse relationship between these two conditions. However, no further attempt has been made to validate this relationship. This study set out to assess the correlation between diverticulosis and colonic redundancy. METHODS: Redundant colon, diverticulosis and patient demographics were recorded during colonoscopy...
September 20, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28930849/analysis-of-risk-factors-for-colonic-diverticular-bleeding-and-recurrence
#2
Masato Taki, Tadayuki Oshima, Katsuyuki Tozawa, Yukako Taniguchi, Toshihiko Tomita, Yoshio Ohda, Hirokazu Fukui, Jiro Watari, Hiroto Miwa
The increase in incidence of colonic diverticular bleeding is relative to an age-related rise in the incidence of colonic diverticulosis and use of antithrombotic medication. However, risk factors related to the onset, recurrence, and prophylaxis have not been established. Therefore, we aimed to determine risk factors for the onset and recurrence of colonic diverticular bleeding.An age- and sex-matched case-control study was performed to assess the risk factors for the onset of colonic diverticular bleeding...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28924595/development-and-validation-of-an-algorithm-to-complete-colonoscopy-using-standard-endoscopes-in-patients-with-prior-incomplete-colonoscopy
#3
Melinda C Rogers, Andrew Gawron, David Grande, Rajesh N Keswani
BACKGROUND AND STUDY AIMS:  Incomplete colonoscopy may occur as a result of colon angulation (adhesions or diverticulosis), endoscope looping, or both. Specialty endoscopes/devices have been shown to successfully complete prior incomplete colonoscopies, but may not be widely available. Radiographic or other image-based evaluations have been shown to be effective but may miss small or flat lesions, and colonoscopy is often still indicated if a large lesion is identified. The purpose of this study was to develop and validate an algorithm to determine the optimum endoscope to ensure completion of the examination in patients with prior incomplete colonoscopy...
September 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28884385/low-frequency-of-polyps-in-colonic-regions-with-diverticulosis
#4
Irving Levine, Amol S Rangnekar, Aaron Z Tokayer
PURPOSE: Conflicting evidence exists regarding any association between diverticulosis and adenomatous polyps. We evaluated the prevalence of polyps and cancer in colonic regions containing diverticula. METHODS: Six hundred consecutive colonoscopy reports from a single endoscopist were reviewed to determine prevalence and location of diverticulosis and polyps. Additionally, pathology reports of 88 colon cancer resection specimens were reviewed for the presence of diverticulosis, and compared with expected prevalence of diverticulosis in that colonic region based on the collected colonoscopy data...
September 7, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28837412/recurrence-of-colonic-diverticulitis-identifying-predictive-ct-findings-retrospective-cohort-study
#5
Elliot C Dickerson, Suzanne T Chong, James H Ellis, Kuanwong Watcharotone, Bin Nan, Matthew S Davenport, Mahmoud Al-Hawary, Michael B Mazza, Rafat Rizk, Arden M Morris, Richard H Cohan
Purpose To identify computed tomographic (CT) findings that are predictive of recurrence of colonic diverticulitis. Materials and Methods Institutional review board approval was obtained for this HIPAA-compliant, retrospective cohort study. Six abdominal fellowship-trained radiologists reviewed the CT studies of 440 consecutive subjects diagnosed with acute colonic diverticulitis between January 2004 and May 2008 to determine the involved segments, maximum wall thickness in the inflamed segment, severity of diverticulosis, presence of complications (abscess, fistula, stricture, or perforation), and severity of the inflammation...
August 24, 2017: Radiology
https://www.readbyqxmd.com/read/28815036/bacterial-stimuli-activate-nitric-oxide-colonic-mucosal-production-in-diverticular-disease-protective-effects-of-l-casei-dg%C3%A2-lactobacillus-paracasei-cncm-i-1572
#6
Fabio Turco, Paolo Andreozzi, Ilaria Palumbo, Francesco Paolo Zito, Martina Cargiolli, Walter Fiore, Nicola Gennarelli, Giovanni Domenico De Palma, Giovanni Sarnelli, Rosario Cuomo
BACKGROUND: Micro-inflammation and changes in gut microbiota may play a role in the pathogenesis of diverticular disease (DD). OBJECTIVE: The objective of this article is to evaluate the expression of nitric oxide (NO)-related mediators and S100B in colonic mucosa of patients with DD in an ex vivo model of bacterial infection. METHODS: Intestinal biopsies obtained from patients with diverticulosis, symptomatic uncomplicated diverticular disease (SUDD) and SUDD with previous acute diverticulitis (SUDD+AD) were stimulated with the probiotic L...
August 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28776378/colonic-diverticulosis-and-the-metabolic-syndrome-an-association
#7
Cristina Teixeira, Daniel Trabulo, Suzane Ribeiro, Cláudio Rodrigues Martins, Ana Luísa Alves, Isabelle Cremers, Ana Paula Oliveira
BACKGROUND AND OBJECTIVES: Colonic diverticulosis (CD) is related to advanced age and a lack of dietary fiber. Recently, several studies have shown that metabolic syndrome (MS) is also implicated in the etiopathogenesis of CD. This study aimed to assess the association between MS, obesity and CD. METHODS: This was a prospective study of a one-year duration. The MS was defined according to the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III)...
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28768296/dietary-pattern-and-colonic-diverticulosis
#8
Antonio Tursi
PURPOSE OF REVIEW: To assess the role of dietary pattern on the occurrence of colonic diverticulosis, diverticular disease and acute diverticulitis. RECENT FINDINGS: High-fiber diet does not prevent diverticulosis occurrence, and results about prevention/treatment of diverticular disease and acute diverticulitis are still conflicting.No association was seen between nut, corn or popcorn consumption and occurrence of diverticulosis, diverticular disease and acute diverticulitis...
September 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/28723285/case-244-systemic-amyloidosis-a-complication-of-waldenstr%C3%A3-m-macroglobulinemia
#9
Maja Hrabak-Paar, Marko Kralik
History A 68-year-old man was admitted to the hospital for work-up because of generalized fatigue, anorexia, chronic diarrhea, and weight loss. Laboratory work-up revealed an erythrocyte sedimentation rate of 58 mm/h (reference range, 3-23 mm/h), a hemoglobin level of 14.1 g/dL (reference range, 13.8-17.5 g/dL), a leukocyte count of 8.1 × 10(9)/L (reference range, [3.4-9.7] × 10(9)/L), a platelet count of 223 × 10(9)/L (reference range, [158-424] × 10(9)/L), an alkaline phosphatase level of 85 U/L (1.42 μkat/L) (normal level, <142 U/L [2...
August 2017: Radiology
https://www.readbyqxmd.com/read/28683025/visceral-pain-as-a-triggering-factor-for-fibromyalgia-symptoms-in-comorbid-patients
#10
Raffaele Costantini, Giannapia Affaitati, Ursula Wesselmann, Peter Czakanski, Maria Adele Giamberardino
Fibromyalgia syndrome (FMS) is a central sensitization syndrome; however, peripheral pain sources potentially exacerbate its symptoms of chronic diffuse musculoskeletal pain and hyperalgesia. This prospective study evaluated visceral pain as a possible triggering factor for FMS pain and hyperalgesia in comorbid patients. Women with (1) FMS + irritable bowel syndrome (IBS); (2) FMS + primary dysmenorrhea (Dys); (3) FMS + Dys secondary to endometriosis (Endo); (4) FMS + colon diverticulosis (Div) were compared with FMS-only women, for fibromyalgia pain (number and intensity of episodes and analgesic consumption) over comparable periods and for somatic hyperalgesia (electrical and pressure pain thresholds) in painful (tender points) and control areas (trapezius, deltoid, quadriceps muscles, and overlying subcutis and skin)...
July 3, 2017: Pain
https://www.readbyqxmd.com/read/28623877/5-aminosalicylic-acid-agents-for-prevention-of-recurrent-diverticulitis-a-systematic-review-and-meta-analysis
#11
Seigo Urushidani, Akira Kuriyama, Masami Matsumura
BACKGROUND AND AIM: Prevalence of colonic diverticulosis is increasing worldwide with age, and up to 25% of patients who have colonic diverticulosis might experience diverticulitis. However, a definitive approach of preventing recurrent diverticulitis remains unknown. 5-aminosalicylic acid (5-ASA) agents are anti-inflammatory agents and have been used to prevent recurrent diverticulitis, and there have been some randomized, clinical trials (RCTs). However, the efficacy results for secondary prevention in uncomplicated diverticulitis differed across studies...
June 17, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28619727/rna-seq-implicates-deregulation-of-the-immune-system-in-the-pathogenesis-of-diverticulitis
#12
Kathleen M Schieffer, Christine S Choi, Scott Emrich, Leonard Harris, Sue Deiling, Dipti M Karamchandani, Anna Salzberg, Yuka I Kawasawa, Gregory S Yochum, Walter A Koltun
Individuals with diverticula or outpouchings of the colonic mucosa and submucosa through the colonic wall have diverticulosis, which is usually asymptomatic. In 10-25% of individuals, the diverticula become inflamed, resulting in diverticulitis. Very little is known about the pathophysiology or gene regulatory pathways involved in the development of diverticulitis. To identify these pathways, we deep sequenced RNAs isolated from full-thickness sections of sigmoid colon from diverticulitis patients and control individuals...
September 1, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/28603053/colonic-diverticula-are-not-associated-with-mucosal-inflammation-or-chronic-gastrointestinal-symptoms
#13
Anne F Peery, Temitope O Keku, Cassandra Addamo, Amber N McCoy, Christopher F Martin, Joseph A Galanko, Robert S Sandler
BACKGROUND & AIMS: Colonic diverticulosis has been reported to be associated with low-grade mucosal inflammation, possibly leading to chronic gastrointestinal symptoms. However, there is poor evidence for this association. We aimed to determine mucosal inflammation and whether diverticula are associated with chronic gastrointestinal symptoms. We explored whether inflammation was present among symptomatic participants with and without diverticula. METHODS: We analyzed data from a prospective study of 619 patients undergoing a screening colonoscopy from 2013 through 2015 at the University of North Carolina Hospital in Chapel Hill, North Carolina...
June 8, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28523327/complicated-diverticulitis-in-a-de-novo-kidney-transplanted-patient
#14
Liliana Ana TuŢă, Mădălina Boşoteanu, Eugen Dumitru, Mariana Deacu
Diverticular disease is frequent amongst the elderly and immunosuppressed patients. It mainly presents as sigmoid diverticulitis, but severe complications, like bleedings, infections and colon perforation may occur, frequently due to immunosuppressive therapy. Moreover, antibiotherapy and hemostatics may not efficiently control evolution in such cases. Early diagnose and adequate treatment of colonic diverticulosis complicated with lower gastrointestinal bleeding and diverticulitis in immunocompromised patients...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28491166/toothpick-meningitis
#15
Qiao Zhou, Neera Singh, Bradley Monteforte
A 66-year-old male with a history of hypertension, back pain, diverticulosis and anal fistula presents with acute onset syncopal episodes, worsening back pain, and altered mental status. The patient exhibited considerable leukocytosis but was hemodynamically stable. CT imaging of the head revealed a gas pattern in the posterior fossa and velum interpositum. CT imaging of the abdomen and pelvis revealed a needle-like foreign body traversing the left sacrum to the sigmoid colon. A lumbar puncture revealed meningitis...
June 2017: Radiology case reports
https://www.readbyqxmd.com/read/28469355/segmental-colitis-associated-with-diverticulosis-is-it-the-coexistence-of-colonic-diverticulosis-and-inflammatory-bowel-disease
#16
REVIEW
John Schembri, John Bonello, Dimitrios K Christodoulou, Konstantinos H Katsanos, Pierre Ellul
Segmental colitis associated with diverticulosis (SCAD) is an inflammatory process that affects colonic luminal mucosa in segments that are also affected by diverticulosis. Its prevalence varies between 1.15% and 11.4% amongst those suffering from diverticular disease (DD). Being closely associated with DD, it is slightly commoner in males and usually presents in the sixth decade of life. Although the exact pathogenesis of SCAD is unknown, it is probably heterogeneous and includes mechanisms that also play a part in inflammatory bowel disease (IBD)...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28466633/management-of-diverticulosis-what-s-new
#17
REVIEW
Walter Elisei, Giovanni Brandimarte, Antonio Tursi
The incidence of diverticulosis and diverticular disease (DD) of the colon, including acute diverticulitis, is increasing worldwide, and becoming a significant burden on national health systems in terms of direct and indirect costs. Thus, significant efforts are now being focused to identify the correct therapeutic approach to treat symptomatic patients and to prevent diverticulitis. Fiber, non-absorbable antibiotics, 5-aminosalicylic acid and probioticsare currently being investigated in this way. Unfortunately, current evidences on the effectiveness of some medical treatment in preventing acute diverticulitis recurrence are still lacking...
October 2017: Minerva Medica
https://www.readbyqxmd.com/read/28453588/-diverticular-disease-myths-and-realities
#18
REVIEW
Daniela Fluxá, Rodrigo Quera
Diverticulosis and diverticular disease of the colon are common conditions in Western countries. The incidence and prevalence of these diseases are increasing and becoming significant for health systems. A growing body of knowledge is shifting the paradigm of the pathogenesis and treatment of diverticular disease. Low-grade inflammation, altered intestinal microbiota, visceral hypersensitivity, and abnormal colonic motility have been identified as factors leading to diverticular disease. The risk of developing diverticulitis among individuals with diverticulosis is lower than 10 to 25%...
February 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28438753/complicated-small-bowel-diverticular-disease-a-case-series
#19
Linden Karas, Mohammed Asif, Victor Chun, Farrukh A Khan
Small bowel diverticulosis of the jejunum and ileum is an uncommon finding with a prevalence rate of 0.2% to 1.3% at autopsy and 0.3% to 1.9% on small bowel studies. Diagnosis can be difficult because there are no pathognomonic features or clinical symptoms that are specific for small bowel diverticulosis. Though rare, it is critical to keep the possibility of small bowel diverticulosis in mind when evaluating cases of malabsorption, chronic abdominal pain, haemorrhage, perforation and intestinal obstruction, especially in patients with connective tissue disorders, a family history of diverticula and a personal history of colonic diverticulosis...
April 23, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28436177/limited-evidence-of-abnormal-intra-colonic-pressure-profiles-in-diverticular-disease-a-systematic-review
#20
REVIEW
R Jaung, J Robertson, G O'Grady, T Milne, D Rowbotham, I P Bissett
AIM: Abnormal colonic pressure profiles and high intraluminal pressures are postulated to contribute to the formation of sigmoid colon diverticulosis and the pathophysiology of diverticular disease (DD). This study aimed to review evidence for abnormal colonic pressure profiles in diverticulosis. METHOD: All published studies investigating colonic pressure in patients with diverticulosis were searched in three databases (MEDLINE, EMBASE, SCOPUS). No language restrictions were applied...
April 24, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
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