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https://www.readbyqxmd.com/read/28816743/elastic-staining-in-differentiating-between-follicular-streamers-and-follicular-scars-in-horizontal-scalp-biopsy-sections
#1
Timothy Tan, Joan Guitart, Pedram Gerami, Pedram Yazdan
BACKGROUND: Accurate identification of follicular streamers versus follicular scars on horizontal scalp biopsy sections is important to differentiate between cicatricial and noncicatricial alopecias. However, distinguishing between them can be difficult especially in nonoptimal specimens. The utility of elastic Verhoeff-Van Gieson (EVG) stain in cicatricial alopecias has been described on vertical sections, but its evaluation on horizontal sections has not been performed. METHODS: Sixty-four cicatricial alopecias (25 lichen planopilaris, 29 central centrifugal cicatricial alopecias, and 10 discoid lupus erythematosus) and 53 noncicatricial alopecias (34 androgenic alopecia, 8 telogen effluvium, and 11 alopecia areata) were identified, and EVG staining was performed on horizontal sections...
August 9, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28816697/sub-galeal-pneumocele-20-years-after-cochlear-implantation
#2
Casey Hay, Nishant Sharma, Arun Gadre
This case report documents a rare case of a subgaleal pneumocele occurring more than 20 years after cochlear implantation. On presentation, the presence of air under the scalp followed vigorous nose blowing was observed. The patient was treated conservatively with a pressure dressing, which resulted in complete resolution of the surgical emphysema. Only a handful of such cases have been reported in the literature. Most of these cases occur early after cochlear implantation. Our case is even more unique as it occurred 24 years following implantation and presented with a painless swelling associated with deterioration in cochlear implant performance...
August 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28815668/primary-low-grade-neuroendocrine-carcinoma-of-the-skin-an-exceedingly-rare-entity
#3
Tiffany Y Chen, Annie O Morrison, Joe Susa, Clay J Cockerell
Low-grade neuroendocrine tumors (NET), also known as carcinoid tumor, commonly arise from the gastrointestinal and pulmonary tracts, but rarely occur in the skin. Cutaneous NET typically occurs as metastases or high grade primary lesions, called Merkel cell carcinoma. In the few cases described in literature, primary low-grade neuroendocrine carcinomas of the skin (LGNECS) are usually indolent cutaneous nodules, presenting on the head and trunk of elderly patients. LGNECS tumors are histologically similar to its counterparts arising in other anatomic locations...
August 16, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28814623/a-3-week-old-with-an-isolated-blueberry-muffin-rash
#4
John B Darby, Gregory Valentine, Kirsty Hillier, Raegan Hunt, C Mary Healy, Valeria Smith, Wendy Allen-Rhoades
A 3-week-old boy, former 39-week term infant, presented to the emergency department with a rash. One week before presentation, he developed dark, purple papules on his forehead, which then spread to the abdomen and inguinal regions. Throughout this time, he was eating well, gaining weight, developing appropriately, and was afebrile without cough, congestion, or rhinorrhea. On presentation, the patient was well appearing with normal vital signs. His weight was 4.83 kg (86th percentile for age), his length was 56 cm (47th percentile for age), and his head circumference was 37 cm (62nd percentile for age)...
June 2, 2017: Pediatrics
https://www.readbyqxmd.com/read/28813949/monitoring-brain-potentials-to-guide-neurorehabilitation-of-tracking-impairments
#5
Boris Yazmir, Miriam Reiner
Motor impairments come in different forms. One class of motor impairments, relates to accuracy of tracking a moving object, as, for instance, when chasing in an attempt to catch it. Here we look at neural signals associated with errors in tracking, and the implications for brain-computer-interfaces that target impairment-tailored rehabilitation. As a starting point, we characterized EEG signals evoked by tracking errors during continuous natural motion, in healthy participants. Participants played a virtual 3D, ecologically valid haptic tennis game, and had to track a moving tennis ball in order to hit and send the ball towards the opponent's court...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813557/facial-erosive-pustular-dermatosis-after-cosmetic-resurfacing
#6
Julie E Mervak, Stephanie D Gan, Emily H Smith, Frank Wang
Importance: Erosive pustular dermatosis (EPD) is a rare condition that typically affects actinically damaged skin of the scalp. Characterized by sterile pustules, erosions, and crusts, EPD is difficult to treat and heals slowly. The exact cause of EPD is unknown, although trauma is an inciting factor. Objective: To describe 3 women who presented with prolonged facial erosions after cosmetic resurfacing procedures, specifically fully ablative carbon dioxide laser or medium-depth chemical peel...
August 16, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28812454/risk-factors-for-intrapartum-acidemia-a-cohort-study
#7
Stina Wretler, Lennart Nordström, Sophie Graner, Malin Holzmann
PURPOSE: Birth acidemia is associated with short- and long-term morbidity in the child. Optimal intrapartum surveillance and timely interventions may reduce the incidence of these outcomes. Knowledge about conditions which increase the risks might be beneficial for optimal care. The aim with this study was to identify factors which increased the risk for lactacidemia in fetal scalp blood. MATERIALS AND METHODS: A secondary analysis of a cohort study performed at Karolinska University Hospital Stockholm Sweden between February 2009 and February 2011...
August 16, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28811195/epileptic-interictal-discharges-are-more-frequent-during-nrem-slow-wave-downstates
#8
Péter Przemyslaw Ujma, Péter Halász, Anna Kelemen, Dániel Fabó, Loránd Erőss
Epileptiform activity in various but not all epilepsy and recording types and cerebral areas is more frequent in NREM sleep, and especially during sleep periods with high-amplitude EEG slow waves. Slow waves synchronize high-frequency oscillations: physiological activity from the theta through the gamma band usually appears during scalp-positive upstates while epileptiform activity occurs at transitory phases and the scalp-negative downstate. It has been proposed that interictal discharges (IIDs) are facilitated by the high degree of neuronal firing synchrony during slow wave transitory and downstates...
August 12, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28811115/recurrence-of-cutaneous-coccidioidomycosis-6-years-after-valley-fever-a-case-presentation-and-literature-review
#9
Rana Shahab, Nasir K Amra, Rola Rabah, Justin Saunar, Joan Soriano, Jaffar A Al-Tawfiq
Coccidioidomycosis is usually acquired by inhalation of spores of Coccidioides immitis and C. posadasii. The disease ranges from a self-limited acute pneumonia (Valley Fever) to a disseminated disease. We present a 44-year-old healthy male who had patchy hair loss of several months duration resembling discoid lupus. He developed a firm non-scaly red plaque on the right forehead. Initial biopsy showed spongiotic dermatitis, and he was treated with systemic steroids. He then developed forehead and periorbital cellulitis and was treated with systemic antibiotics...
July 8, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28809993/adalimumab-in-chronic-plaque-psoriasis-a-clinical-guide
#10
Jashin J Wu, W C Valdecantos
<p>Psoriasis is a common, inflammatory disease that manifests itself as lesions on the skin, which greatly impacts the physical and psychological wellbeing of those affected. The current goal of treatment in psoriasis is to improve the signs and symptoms of disease, whilst minimizing the burden of disease on patient health-related quality of life. Psoriasis can also be associated with other comorbidities such as joint disease, cardiovascular disease, and depression, which can add to the complexity of treatment...
August 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28809777/pigmented-epithelioid-melanocytoma-pem-animal-type-melanoma-atm-quest-for-an-origin-report-of-one-unusual-case-indicating-follicular-origin-and-another-arising-in-an-intradermal-nevus
#11
Ashley Tarasen, J Andrew Carlson, M Kathryn Leonard, Glenn Merlino, David Kaetzel, Andrzej T Slominski
Pigmented epithelioid melanocytoma (PEM) is a tumor encompassing epithelioid blue nevus of Carney complex (EBN of CNC) and was previously termed animal-type melanoma. Histologically PEMs are heavily pigmented spindled and epithelioid dermal melanocytic tumors with infiltrative borders, however, their origin remains unclear. Stem cells for the epidermis and hair follicle are located in the bulge area of the hair follicle with the potential to differentiate into multiple lineages. Multiple cutaneous carcinomas, including follicular cutaneous squamous cell carcinoma (FSCC), are thought to arise from stem cells in the follicular bulge...
August 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28809616/a-method-for-determining-when-the-superficial-scalp-arteries-are-the-source-of-migraine-pain
#12
Elliot Shevel
In some patients the pain of migraine originates in the extracranial cranial arteries. This article describes the location and a logical examination sequence of the vessels most frequently involved in migraine pain.
July 28, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28807860/hidden-markov-modeling-of-frequency-following-responses-to-mandarin-lexical-tones
#13
Fernando Llanos, Zilong Xie, Bharath Chandrasekaran
BACKGROUND: The frequency-following response (FFR) is a scalp-recorded electrophysiological potential reflecting phase-locked activity from neural ensembles in the auditory system. The FFR is often used to assess the robustness of subcortical pitch processing. Due to low signal-to-noise ratio at the single-trial level, FFRs are typically averaged across thousands of stimulus repetitions. Prior work using this approach has shown that subcortical encoding of linguistically-relevant pitch patterns is modulated by long-term language experience...
August 11, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28807253/interdisciplinary-reconstruction-of-oncological-resections-at-the-skull-base-scalp-and-facial-region
#14
REVIEW
P M Vogt, T R Mett, G F Broelsch, C Radtke, N-C Gellrich, J K Krauss, M Samii, R Ipaktchi
Extensive bone and soft tissue defects of the skull require unique plastic and reconstructive techniques to avoid and optimize aesthetic appearance following oncological resections. Procedures are ideally planned in an interdisciplinary board composed of neurosurgery, otorhinolaryngology, plastic and reconstructive surgery to facilitate reconstructive procedures of soft tissue and bone as early as possible in one approach. Large resections may require plastic surgery involvement from the beginning. Herein, we describe the function of a multidisciplinary approach to complex oncologic resections of the cranial base, scalp, and facial regions for neuro-oncologic patients...
September 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28805853/the-activity-of-lone-pair-contributing-to-shg-response-in-bismuth-borates-a-combination-investigation-from-experiment-and-dft-calculation
#15
Cong Hu, Miriding Mutailipu, Ying Wang, Fengjiao Guo, Zhihua Yang, Shilie Pan
Second harmonic generation (SHG) response is one of the most essential properties of nonlinear optical (NLO) materials. To achieve relatively strong SHG response, a feasible strategy is to introduce stereochemically active lone pair (SCALP) cations, such as Bi(3+). NLO materials with Bi(3+) usually exhibit a huge difference in SHG response, the inner correlation between the activity of SCALP and SHG response still being unclear owing to the lack of quantization estimation of the intensity of SCALP. Based on the calculation results of density functional theory (DFT), we develop a theoretical method to compute the intensity of the Bi-6s SCALP, which could describe the stereochemical behavior and exert significantly influences on some apparent optical properties, such as SHG response...
August 14, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28802002/congenital-neurocristic-cutaneous-hamartoma-with-poliosis-a-case-report
#16
Lauren M Wilson, Knox J Beasley, Timothy C Sorrells, Viviana V Johnson
Neurocristic Cutaneous Hamartomas (NCH) are rare, pigmented skin lesions derived from the abnormal migration of neural crest cells. 1 2 We report the case of a 57-year-old female with a congenital localized area of poliosis and underlying pigmented patch on her scalp. Analysis of two punch biopsies yielded features consistent with NCH. Histopathology revealed schwannian-differentiated spindle cells and melanocytic components in the dermis. The spindle cells stained positively with S-100 and the stroma showed a prominent CD34 stain...
August 12, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28800744/physiological-artifacts-in-scalp-eeg-and-ear-eeg
#17
Simon L Kappel, David Looney, Danilo P Mandic, Preben Kidmose
BACKGROUND: A problem inherent to recording EEG is the interference arising from noise and artifacts. While in a laboratory environment, artifacts and interference can, to a large extent, be avoided or controlled, in real-life scenarios this is a challenge. Ear-EEG is a concept where EEG is acquired from electrodes in the ear. METHODS: We present a characterization of physiological artifacts generated in a controlled environment for nine subjects. The influence of the artifacts was quantified in terms of the signal-to-noise ratio (SNR) deterioration of the auditory steady-state response...
August 11, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28800613/ongoing-slow-oscillatory-phase-modulates-speech-intelligibility-in-cooperation-with-motor-cortical-activity
#18
Takayuki Onojima, Keiichi Kitajo, Hiroaki Mizuhara
Neural oscillation is attracting attention as an underlying mechanism for speech recognition. Speech intelligibility is enhanced by the synchronization of speech rhythms and slow neural oscillation, which is typically observed as human scalp electroencephalography (EEG). In addition to the effect of neural oscillation, it has been proposed that speech recognition is enhanced by the identification of a speaker's motor signals, which are used for speech production. To verify the relationship between the effect of neural oscillation and motor cortical activity, we measured scalp EEG, and simultaneous EEG and functional magnetic resonance imaging (fMRI) during a speech recognition task in which participants were required to recognize spoken words embedded in noise sound...
2017: PloS One
https://www.readbyqxmd.com/read/28800031/risk-factors-for-development-of-melanoma-brain-metastasis-and-disease-progression-a-single-center-retrospective-analysis
#19
Laura J Gardner, Morgan Ward, Robert H I Andtbacka, Kenneth M Boucher, Glen M Bowen, Tawnya L Bowles, Adam L Cohen, Kenneth Grossmann, Ying J Hitchcock, Sheri L Holmen, John Hyngstrom, Hung Khong, Martin McMahon, Marcus M Monroe, Carolyn B Ross, Gita Suneja, David Wada, Douglas Grossman
Melanoma metastasis to the brain is associated with a poor prognosis. We sought to determine patient demographics and primary tumor factors associated with the development of brain metastasis (BM) and survival. We also investigated whether the BM detection setting (routine screening vs. symptomatic presentation) affected clinical outcomes. A database of melanoma patients seen from 1999 to 2015 at our institution was reviewed to identify patients who developed BM. Patients with BM were matched by initial stage with patients who did not develop BM as a control group...
August 10, 2017: Melanoma Research
https://www.readbyqxmd.com/read/28796885/photodynamic-therapy-is-more-effective-than-imiquimod-for-actinic-keratosis-in-organ-transplant-recipients-a-randomized-intra-individual-controlled-trial
#20
K Togsverd-Bo, C Halldin, C Sandberg, H Gonzalez, A M Wennberg, S S Sørensen, H C O Wulf, M Haedersdal
BACKGROUND: Actinic keratoses (AKs) in solid organ transplant recipients (OTRs) are difficult-to-treat pre-malignancies and comparison of topical therapies is therefore warranted. OBJECTIVES: In an intra-individual study to compare efficacy and safety of field treatment with methyl aminolevulinate photodynamic therapy (MAL-PDT) and imiquimod (IMIQ) for AKs in OTRs. MATERIALS AND METHODS: OTRs (n=35) with 572 AKs (grade I-III) in two similar areas in the face, scalp, dorsal hands or forearms were included...
August 10, 2017: British Journal of Dermatology
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