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https://www.readbyqxmd.com/read/28231172/chemometrics-methods-for-specificity-authenticity-and-traceability-analysis-of-olive-oils-principles-classifications-and-applications
#1
REVIEW
Habib Messai, Muhammad Farman, Abir Sarraj-Laabidi, Asma Hammami-Semmar, Nabil Semmar
BACKGROUND: Olive oils (OOs) show high chemical variability due to several factors of genetic, environmental and anthropic types. Genetic and environmental factors are responsible for natural compositions and polymorphic diversification resulting in different varietal patterns and phenotypes. Anthropic factors, however, are at the origin of different blends' preparation leading to normative, labelled or adulterated commercial products. Control of complex OO samples requires their (i) characterization by specific markers; (ii) authentication by fingerprint patterns; and (iii) monitoring by traceability analysis...
November 17, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28230777/cryptomphalus-aspersa-mollusc-egg-extract-promotes-regenerative-effects-in-human-dermal-papilla-stem-cells
#2
María Teresa Alameda, Esther Morel, Concepción Parrado, Salvador González, Ángeles Juarranz
The aim of this study was to test, by an in vitro approach, whether a natural extract derived from eggs of the mollusc Cryptomphalus aspersa (e-CAF) that seems to present regenerative properties, can enhance the mobilization of human hair dermal papilla cells (HHDPCs) and play a role on tissue repair and regeneration. We have tested HHDPCs proliferation by the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium-bromide (MTT) assay; cell migration by using a wound healing assay, as well as the modulation of the expression of cytoskeletal (F-actin and vimentin) and cell adhesion to the extracellular matrix (ECM) (vinculin and P-FAK) proteins...
February 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28230454/adherence-persistence-and-health-care-costs-for-patients-receiving-dipeptidyl-peptidase-4-inhibitors
#3
Karen L Rascati, Karen Worley, Yunus Meah, Damian Everhart
BACKGROUND: The dipeptidyl peptidase-4 (DPP-4) inhibitors are among the newer, yet more established, classes of diabetes medications. OBJECTIVE: To compare adherence, persistence, and health care costs among patients taking DPP-4 inhibitors. METHODS: Claims were extracted from Humana Medicare Advantage Prescription Drug (MAPD) or commercial plans for patients aged > 18 years with ≥ 1 prescription filled for a DPP-4 inhibitor between July 1, 2011, and March 31, 2013...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230350/cyclic-voltammetry-probe-approach-curves-with-alkali-amalgams-at-mercury-sphere-cap-scanning-electrochemical-microscopy-probes
#4
Zachary J Barton, Joaquín Rodríguez-López
We report a method of precisely positioning a Hg-based ultramicroelectrode (UME) for scanning electrochemical microscopy (SECM) investigations of any substrate. Hg-based probes are capable of performing amalgamation reactions with metal cations, which avoid unwanted side reactions and positive feedback mechanisms that can prove problematic for traditional probe positioning methods. However, prolonged collection of ions eventually leads to saturation of the amalgam accompanied by irreversible loss of Hg. In order to obtain negative feedback positioning control without risking damage to the SECM probe, we implement cyclic voltammetry probe approach surfaces (CV-PASs), consisting of CVs performed between incremental motor movements...
February 23, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28230344/fully-automatic-in-syringe-magnetic-stirring-assisted-dispersive-liquid-liquid-microextraction-hyphenated-to-high-temperature-torch-integrated-sample-introduction-system-inductively-coupled-plasma-spectrometer-with-direct-analysis-of-the-organic-phase
#5
Raquel Sanchez, Burkhard Horstkotte, Katerina Fikarova, Hana Sklenářová, Salvador Maestre, Manuel Miró, José Luis Todoli
A proof of concept study involving the on-line coupling of automatic dispersive liquid-liquid microextraction (DLLME) to ICP OES with direct introduction and analysis of the organic extract is herein reported for the first time. The flow-based analyzer features a Lab-In-Syringe (LIS) setup with an integrated stirring system, a Meinhard® nebulizer in combination with a heated single-pass spray chamber, and a rotary injection valve, used as on-line interface between the microextraction system and the detection instrument...
February 23, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28230230/bronchoscopic-lung-volume-reduction-procedures-for-chronic-obstructive-pulmonary-disease
#6
REVIEW
Joseph Em van Agteren, Khin Hnin, Dion Grosser, Kristin V Carson, Brian J Smith
BACKGROUND: In the recent years, a variety of bronchoscopic lung volume reduction (BLVR) procedures have emerged that may provide a treatment option to participants suffering from moderate to severe chronic obstructive pulmonary disease (COPD). OBJECTIVES: To assess the effects of BLVR on the short- and long-term health outcomes in participants with moderate to severe COPD and determine the effectiveness and cost-effectiveness of each individual technique. SEARCH METHODS: Studies were identified from the Cochrane Airways Group Specialised Register (CAGR) and by handsearching of respiratory journals and meeting abstracts...
February 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28229991/a-novel-mutation-in-the-pyrin-domain-of-the-nod-like-receptor-family-pyrin-domain-containing-protein-3-in-muckle-wells-syndrome
#7
Jian Hu, Yun Zhu, Jian-Zhong Zhang, Rong-Guang Zhang, Hou-Min Li
BACKGROUND: Cryopyrin-associated periodic syndrome (CAPS) is a group of rare, heterogeneous autoinflammatory disease characterized by interleukin (IL)-1β-mediated systemic inflammation and clinical symptoms involving skin, joints, central nervous system, and eyes. It encompasses a spectrum of three clinically overlapping autoinflammatory syndromes including familial cold autoinflammatory syndrome, Muckle-Wells syndrome (MWS), and neonatal-onset multisystem inflammatory disease. CAPS is associated with gain-of-function missense mutations in NOD-like receptor family pyrin domain-containing protein 3 (NLRP3), the gene encoding NLRP3...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28228630/social-activities-of-older-men-who-require-daily-support-and-the-purpose-of-such-activities
#8
Michiyo Hirano, Kazuko Saeki, Izumi Ueda, Hikaru Honda, Yoshiko Mizuno
Objectives The purpose of this study was to analyze the social activities of older men who require daily support, and to clarify the purpose of such activities, in order to develop effective living support and preventive long-term care service, suitable for this population.Methods Individual, semi-structured interviews were conducted with 17 older men. Data were analyzed using inductive and qualitative methods.Results Four categories of social activities were identified, and four categories of purposes of these social activities were extracted...
2017: [Nihon Kōshū Eisei Zasshi] Japanese Journal of Public Health
https://www.readbyqxmd.com/read/28228365/isoquinoline-alkaloids-from-coptis-japonica-stimulate-the-myoblast-differentiation-via-p38-map-kinase-and-akt-signaling-pathway
#9
Heyjin Lee, Le Thi Tuong, Ji Hye Jeong, Sang-Jin Lee, Gyu-Un Bae, Jae-Ha Ryu
To overcome the muscle atrophy, such as cachexia and sarcopenia, we tried to find myogenic agents from medicinal plants. From myogenic extract of Coptis japonica, we purified six isoquinoline alkaloids and evaluated their effects on transactivation of myoD and MHC expression in C2C12 cells during differentiation process. Among obtained compounds, magnoflorine most efficiently enhanced the myoblast differentiation by activating the p38 MAP kinase and Akt pathway, and also increased the number of multinucleated and cylinder-shaped myotubes...
February 4, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28228097/alkaloid-extracts-from-combretum-zeyheri-inhibit-the-growth-of-mycobacterium-smegmatis
#10
Tafadzwa Nyambuya, Ruvimbo Mautsa, Stanley Mukanganyama
BACKGROUND: Current tuberculosis regimens have failed to combat the issue of drug resistance and ethno medicines may represent a possible source of antimycobacterial agents. Combretum species are well known in African traditional medicines and used for various ailments including pneumonia, venereal diseases like syphilis, mental problems, relief of sore throats and colds, fever, and chest coughs associated with tuberculosis. Alkaloids function as either hydrogen-acceptor or hydrogen-donor in hydrogen bonding critical for the interaction between targets thus, potentiating effects of curative agents on diseases...
February 23, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28227901/identifying-montages-that-best-detect-the-electroencephalogram-power-spectrum-alteration-during-freezing-of-gait-in-parkinson-s-disease-patients
#11
Quynh Tran Ly, A M Ardi Handojoseno, Moran Gilat, Nghia Nguyen, Rifai Chai, Yvonne Tran, Simon J G Lewis, Hung T Nguyen, Quynh Tran Ly, A M Ardi Handojoseno, Moran Gilat, Nghia Nguyen, Rifai Chai, Yvonne Tran, Simon J G Lewis, Hung T Nguyen, Nghia Nguyen, A M Ardi Handojoseno, Moran Gilat, Hung T Nguyen, Yvonne Tran, Simon J G Lewis, Quynh Tran Ly, Rifai Chai
Our research team has previously used four Electroencephalography (EEG) leads to successfully detect and predict Freezing of Gait (FOG) in Parkinson's disease (PD). However, it remained to be determined whether these four sensor locations that were arbitrarily chosen based on their role in motor control are indeed the most optimal for FOG detection. The aim of this study was therefore to determine the most optimal location and combination of sensors to detect FOG amongst a 32-channel EEG montage using our EEG classification system...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227810/noninvasive-eeg-correlates-of-overground-and-stair-walking
#12
Justin A Brantley, Trieu Phat Luu, Recep Ozdemir, Fangshi Zhu, Anna T Winslow, Helen Huang, Jose L Contreras-Vidal, Justin A Brantley, Trieu Phat Luu, Recep Ozdemir, Fangshi Zhu, Anna T Winslow, Helen Huang, Jose L Contreras-Vidal, Fangshi Zhu, Recep Ozdemir, Justin A Brantley, Helen Huang, Anna T Winslow, Jose L Contreras-Vidal, Trieu Phat Luu
Automated walking intention detection remains a challenge in lower-limb neuroprosthetic systems. Here, we assess the feasibility of extracting motor intent from scalp electroencephalography (EEG). First, we evaluated the corticomuscular coherence between central EEG electrodes (C1, Cz, C2) and muscles of the shank and thigh during walking on level ground and stairs. Second, we trained decoders to predict the linear envelope of the surface electromyogram (EMG). We observed significant EEG-led corticomuscular coupling between electrodes and sEMG (tibialis anterior) in the high delta (3-4 Hz) and low theta (4-5 Hz) frequency bands during level walking, indicating efferent signaling from the cortex to peripheral motor neurons...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227782/predicting-short-term-icu-outcomes-using-a-sequential-contrast-motif-based-classification-framework
#13
Shameek Ghosh, Hung Nguyen, Jinyan Li, Shameek Ghosh, Hung Nguyen, Jinyan Li, Shameek Ghosh, Hung Nguyen, Jinyan Li
Critical ICU events like acute hypotension and septic shock are dangerous complications, leading to multiple organ failures and eventual death. Previously, pattern mining algorithms have been employed for extracting interesting rules in various clinical domains. However, the extracted rules are directly investigated by clinicians for diagnosing a disease. Towards this purpose, there is a need to develop advanced prediction models which integrate dynamic patterns to learn a patient's physiological condition...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227768/measures-of-the-brain-functional-network-that-correlate-with-alzheimer-s-neuropsychological-test-scores-an-fmri-and-graph-analysis-study
#14
Soroosh Golbabaei, Amin Dadashi, Hamid Soltanian-Zadeh, Soroosh Golbabaei, Amin Dadashi, Hamid Soltanian-Zadeh, Soroosh Golbabaei, Amin Dadashi, Hamid Soltanian-Zadeh
Neural degeneration in Alzheimer's disease (AD) leads to structural topology deformation that in turn changes brain functionality. The main aim of the present study is to find the brain's functional connectivity network (FCN) correlates of Alzheimer's psychological test scores. To this end, the brain's FCN is extracted from the resting state functional magnetic resonance images (rs-fMRI) of healthy controls and patients with AD and represented as a graph. Then, network measures are calculated from the graphs...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227533/upper-extremity-post-stroke-motion-quality-estimation-with-decision-trees-and-bagging-forests
#15
Sarvenaz Chaeibakhsh, Elissa Phillips, Amanda Buchanan, Eric Wade, Sarvenaz Chaeibakhsh, Elissa Phillips, Amanda Buchanan, Eric Wade, Elissa Phillips, Sarvenaz Chaeibakhsh, Amanda Buchanan, Eric Wade
Stroke is one of the leading causes of long-term disability. Approximately two thirds of stroke survivors require long-term rehabilitation, which suggests the importance of understanding movement quality in real-world settings. To address this need, we have developed an approach that quantifies physical activity and also evaluates performance quality. Accelerometer and gyroscope sensor data are used to measure upper extremity movements and to develop a mathematical framework to relate objective sensor data to clinical performance metrics...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227306/detection-of-motion-and-posture-change-using-an-ir-uwb-radar
#16
Van Nguyen, Abdul Q Javaid, Mary A Weitnauer, Van Nguyen, Abdul Q Javaid, Mary A Weitnauer, Abdul Q Javaid, Mary A Weitnauer, Van Nguyen
Impulse radio ultra-wide band (IR-UWB) radar has recently emerged as a promising candidate for non-contact monitoring of respiration and heart rate. Different studies have reported various radar based algorithms for estimation of these physiological parameters. The radar can be placed under a subject's mattress as he lays stationary on his back or it can be attached to the ceiling directly above the subject's bed. However, advertent or inadvertent movement on part of the subject and different postures can affect the radar returned signal and also the accuracy of the estimated parameters from it...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227262/pulse-transit-time-and-heart-rate-variability-in-sleep-staging
#17
Sobhan Salari Shahrbabaki, Beena Ahmed, Thomas Penzel, Dean Cvetkovic, Sobhan Salari Shahrbabaki, Beena Ahmed, Thomas Penzel, Dean Cvetkovic, Sobhan Salari Shahrbabaki, Beena Ahmed, Thomas Penzel, Dean Cvetkovic
This paper presents a new and robust algorithm for detection of sleep stages by using the lead I of the Electrocardiography (ECG) and a fingertip Photoplethysmography (PPG) sensor, validated using multiple overnight PSG recordings consisting of 20 human subjects (9 insomniac and 11 healthy). Heart Rate Variability (HRV) and Pulse Transit Time (PTT) biomarkers which were extracted from ECG and PPG biosignals then employed to extract features. Distance Weighted k-Nearest Neighbours (DWk-NN) was used as classifier to differentiate sleep epochs...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227034/a-novel-algorithm-for-reducing-false-arrhythmia-alarms-in-intensive-care-units
#18
Chandan Srivastava, Sonal Sharma, Ali Jalali, Chandan Srivastava, Sonal Sharma, Ali Jalali, Ali Jalali, Chandan Srivastava, Sonal Sharma
Alarm fatigue in intensive care units (ICU) is one of the top healthcare issues in the US. False alarms in ICU will decrease the quality of care and staff response time over the alarms. Normally, false alarm will cause desensitization of the clinical staff which leads to warnings and misleading, if the triggered alarm is true. In this study, we have proposed a multi-model ensemble approach to reduce the false alarm rate in monitoring systems. We have used 750 patient records from PhysioNet database. At First arrhythmia based features from electrocardiogram (ECG), arterial blood pressure (ABP) and photoplethysmogram (PPG) features were extracted from the records...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226978/improving-clinical-models-based-on-knowledge-extracted-from-current-datasets-a-new-approach
#19
D Mendes, S Paredes, T Rocha, P Carvalho, J Henriques, J Morais, D Mendes, S Paredes, T Rocha, P Carvalho, J Henriques, J Morais, D Mendes, T Rocha, P Carvalho, J Morais, S Paredes, J Henriques
The Cardiovascular Diseases (CVD) are the leading cause of death in the world, being prevention recognized to be a key intervention able to contradict this reality. In this context, although there are several models and scores currently used in clinical practice to assess the risk of a new cardiovascular event, they present some limitations. The goal of this paper is to improve the CVD risk prediction taking into account the current models as well as information extracted from real and recent datasets. This approach is based on a decision tree scheme in order to assure the clinical interpretability of the model...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226747/automatic-detection-of-neovascularization-on-optic-disk-region-with-feature-extraction-and-support-vector-machine
#20
Shuang Yu, Di Xiao, Yogesan Kanagasingam, Shuang Yu, Di Xiao, Yogesan Kanagasingam, Di Xiao, Yogesan Kanagasingam, Shuang Yu
Neovascularization (NV) is a definitive indicator for the onset of Proliferative Diabetic Retinopathy (PDR). The new vessels are fragile and prone to bleed, leading to high risk of sudden vision loss. Automatic detection of NV is an important task in automatic Diabetic Retinopathy (DR) screening as a consequence of the unmet requirement between the growing number of DR patients and limited number of ophthalmologists. This paper focuses on the computer aided detection of neovascularization in the optic disk region...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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