keyword
https://read.qxmd.com/read/38329618/factors-associated-with-delirium-in-a-real-world-acute-care-setting-analysis-considering-the-interdependence-of-clinical-variables-with-the-frailty-syndrome
#21
JOURNAL ARTICLE
Andrea Ticinesi, Alberto Parise, Davide Delmonte, Chiara Coppi, Beatrice Prati, Nicoletta Cerundolo, Angela Guerra, Antonio Nouvenne, Tiziana Meschi
PURPOSE: Delirium risk assessment in the acute-care setting generally does not account for frailty. The objective of this retrospective study was to identify factors associated with delirium, considering the interdependency of clinical variables with frailty syndrome in complex older patients. METHODS: The clinical records of 587 participants (248 M, median age 84) were reviewed, collecting clinical, anamnestic and pharmacological data. Frailty syndrome was assessed with the Clinical Frailty Scale (CFS)...
February 8, 2024: European Geriatric Medicine
https://read.qxmd.com/read/38329570/palliative-care-psychiatry-building-synergy-across-the-spectrum
#22
REVIEW
Daniel Shalev, Keri Brenner, Rose L Carlson, Danielle Chammas, Sarah Levitt, Paul E Noufi, Gregg Robbins-Welty, Jason A Webb
PURPOSE OF REVIEW: Palliative care (PC) psychiatry is a growing subspecialty focusing on improving the mental health of those with serious medical conditions and their caregivers. This review elucidates the current practice and ongoing evolution of PC psychiatry. RECENT FINDINGS: PC psychiatry leverages training and clinical practices from both PC and psychiatry, addressing a wide range of needs, including enhanced psychiatric care for patients with serious medical illness, PC access for patients with medical needs in psychiatric settings, and PC-informed psychiatric approaches for individuals with treatment-refractory serious mental illness...
February 8, 2024: Current Psychiatry Reports
https://read.qxmd.com/read/38298786/age-related-alterations-in-gray-matter-microstructure-in-older-people-with-remitted-major-depression-at-risk-for-dementia
#23
JOURNAL ARTICLE
John A E Anderson, Neda Rashidi-Ranjbar, Arash Nazeri, Jordan A Chad, Peter Zhukovsky, Benoit H Mulsant, Nathan Herrmann, Linda Mah, Alastair J Flint, Corinne E Fischer, Bruce G Pollock, Tarek K Rajji, Aristotle N Voineskos
BACKGROUND: Major depressive disorder (MDD) in late life is a risk factor for mild cognitive impairment (MCI) and Alzheimer's disease. However, studies of gray matter changes have produced varied estimates of which structures are implicated in MDD and dementia. Changes in gray matter volume and cortical thickness are macrostructural measures for the microstructural processes of free water accumulation and dendritic spine loss. METHODS: We conducted multishell diffusion imaging to assess gray matter microstructure in 244 older adults with remitted MDD ( n  = 44), MCI ( n  = 115), remitted MDD+MCI ( n  = 61), or without psychiatric disorders or cognitive impairment (healthy control participants; n  = 24)...
January 2024: Biol Psychiatry Glob Open Sci
https://read.qxmd.com/read/38295618/-medicine-consumption-as-a-factor-associated-with-the-state-of-fragility-of-the-elderly-patient-in-spain
#24
JOURNAL ARTICLE
J M Ignacio Expósito, N Carrillo Peñas, M Rosety Rodríguez, C Lagares Franco
INTRODUCTION: Frailty in the elderly is a concept in constant evolution, with a significant impact on the morbidity and mortality of patients. We assessed the associative strength of the Timed Up and Go test (TUG) and medication consumption in frailty and associated risk using various methods. MATERIAL AND METHODS: Observational, cross-sectional, multicenter study carried out in 128 Primary Care Centers distributed throughout Spain, has a total sample of 2422 patients over 65 years of age, estimating the prevalence of frailty with the TUG test...
January 30, 2024: Semergen
https://read.qxmd.com/read/38290096/expressed-emotion-in-families-of-people-with-dementia-a-review-of-scale-based-measures
#25
REVIEW
Xiaoji Liu, Wenping Mo, Keigo Takiue, Reiko Kanaya, Yasushi Takeya, Eriko Koujiya, Miyae Yamakawa
PURPOSE: Research on the concept of expressed emotion (EE) has expanded in recent years but its role in dementia still requires elucidation. Understanding the role of EE in the dementia context could help in the development of appropriate interventions. METHOD: The current review synthesized relevant literature to investigate the prevalence and correlates of EE status in families of people with dementia. A comprehensive search of four databases from inception to 2022 produced 2,683 papers; 18 studies met inclusion criteria...
February 2024: Journal of Gerontological Nursing
https://read.qxmd.com/read/38285905/quality-of-life-among-older-adults-with-frailty-a-structural-equation-modeling
#26
JOURNAL ARTICLE
Xiuyan Lan, Bilan Yi, Zijuan Wang
PURPOSE: Frailty is a complex age-related clinical condition among older adults. Quality of life (QOL) among older adults with frailty is an important topic of interest. The current cross-sectional study aimed to develop a structural equation model to identify factors affecting QOL. METHOD: A total of 180 older adults with frailty were recruited from general units in two hospitals in Fuzhou, China. Data were collected using the World Health Organization Quality of Life Brief Version, Pittsburgh Sleep Quality Index, Geriatric Depression Scale-15, and Simplified Coping Style Questionnaire...
January 29, 2024: Journal of Psychosocial Nursing and Mental Health Services
https://read.qxmd.com/read/38269564/-how-potentially-inapropriate-are-psychotropic-drugs-prescribing-in-acute-psychiatric-unit-for-the-elderly-results-from-a-large-multicentric-audit-in-france
#27
JOURNAL ARTICLE
Morgane Houix, Ilia Humbert, Guillaume Mabileau, Guillaume Chapelet, Anne Sauvaget, Bénédicte Gohier, Sophie Armand-Branger, Jean-François Huon, Fanny D'Acremont, Samuel Bulteau
Adverse drug reactions (ADRs) are a major public health issue, especially when it comes to the elderly. Potentially inappropriate prescribing (PIP) are one of the causes of ADRs in older people. A PIP can be defined as a prescription for which the benefit/risk ratio is unfavourable compared to other therapeutic alternatives. Psychotropic drugs are the second highest risk class for ADRs in the elderly. In order to reduce the prevalence of PIP, prescription assistance tools have been created. An inventory of PIP of psychotropic drugs in older patients hospitalized in psychiatry units was carried out in a French regional setting in 2019...
December 1, 2023: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://read.qxmd.com/read/38268483/anxiety-in-late-life-depression-associations-with-brain-volume-amyloid-beta-white-matter-lesions-cognition-and-functional-ability
#28
JOURNAL ARTICLE
Maria Kryza-Lacombe, Michelle T Kassel, Philip S Insel, Emma Rhodes, David Bickford, Emily Burns, Meryl A Butters, Duygu Tosun, Paul Aisen, Rema Raman, Susan Landau, Andrew J Saykin, Arthur W Toga, Clifford R Jack, Robert Koeppe, Michael W Weiner, Craig Nelson, R Scott Mackin
OBJECTIVES: Late-life depression (LLD) is common and frequently co-occurs with neurodegenerative diseases of aging. Little is known about how heterogeneity within LLD relates to factors typically associated with neurodegeneration. Varying levels of anxiety are one source of heterogeneity in LLD. We examined associations between anxiety symptom severity and factors associated with neurodegeneration, including regional brain volumes, amyloid beta (Aβ) deposition, white matter disease, cognitive dysfunction, and functional ability in LLD...
January 25, 2024: International Psychogeriatrics
https://read.qxmd.com/read/38265062/comparative-pharmacokinetic-evaluation-of-glimepiride-orodispersable-and-conventional-tablets-in-rabbits
#29
JOURNAL ARTICLE
Altaf Ur Rahman, Fazli Nasir, Muzna Ali Khattak, Talaya Hidayatullah, Sadia Pervez, Syeda Rabqa Zainab, Arbab Tahir, Shazma Gohar, Gul E Maryam, Waleed H Almalki
OBJECTIVES: Glimepiride Orodispersable Tablets (ODT) were prepared with the goal to have rapid onset of action and higher bioavailability with ease administration to individuals with swallowing difficulty to ameliorate patient compliance. SIGNIFICANCE: Glimepiride is a contemporary hypoglycaemic medication that belongs to the family of sulfonylurea derivatives. It is used in type 2 diabetes mellitus. Compliance adherence remains one of the limitations with the conventional drug delivery system especially in paediatric, geriatric, psychiatric, and travelling patients, for such population ODT provides a good alternate dosage form compared with Commercial Tablets...
January 24, 2024: Drug Development and Industrial Pharmacy
https://read.qxmd.com/read/38262738/the-prognosis-of-delirium-in-older-outpatients
#30
JOURNAL ARTICLE
Daisy Wp Quispel-Aggenbach, Sytse U Zuidema, Hendrika J Luijendijk
BACKGROUND: Delirium is a common and serious neuropsychiatric disorder. The prognosis of delirium in older patients living at home has not been studied often before. The aim of this study is to examine the prognosis of delirium in patients attending a memory clinic of a psychiatric hospital. METHOD: The study population consisted of 85 outpatients diagnosed with delirium between October 2013 and October 2014. Seventeen patients had already been diagnosed as having dementia...
January 23, 2024: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://read.qxmd.com/read/38241061/feasibility-of-using-virtual-reality-in-geriatric-psychiatry
#31
JOURNAL ARTICLE
Sandra Anna Just, Alva Lütt, Paula Siegle, Eva Janina Döring-Brandl
OBJECTIVES: Virtual Reality-based interventions have become an important element of digital mental health, offering accessible and scalable treatment options. However, studies on VR-based approaches in elderly patients are scarce. This explorative study examined the feasibility of using Virtual Reality (VR) for elderly patients with psychiatric illness, focusing on the sense of presence as the primary outcome. METHODS: The study included N = 30 patients between the ages of 59-92 years who were currently in geriatric psychiatric inpatient and day clinic treatment...
January 2024: International Journal of Geriatric Psychiatry
https://read.qxmd.com/read/38235737/exploring-the-characteristics-of-men-aged-55-who-use-mental-health-community-care-and-support-services-a-secondary-analysis-of-the-adult-psychiatric-morbidity-study-in-england
#32
JOURNAL ARTICLE
Alex Vickery
ObjectivesThe aim of this study is to understand the demographic and situational characteristics of men over 55 who have used a community support service. Method: Hierarchical multivariable logistic regression was conducted using anonymised data from the Adult Psychiatric Morbidity Study 2014. Results: Need factors such as having a common mental disorder (CMD), poor general health and having counselling/therapy were the most relevant to use of a community support service. It was more common for older men (85+), single men, and those who reported experiencing several traumatic life events to have used a community support service...
January 18, 2024: Journal of Aging and Health
https://read.qxmd.com/read/38230692/the-care-needs-of-patients-with-cognitive-impairment-in-late-stage-parkinson-s-disease
#33
JOURNAL ARTICLE
Jennifer S Pigott, Bastiaan R Bloem, Stefan Lorenzl, Wassilios G Meissner, Per Odin, Joaquim J Ferreira, Richard Dodel, Anette Schrag
BACKGROUND: Cognitive impairment is common in Parkinson's disease (PD), but care needs and resource use for those with significant cognitive impairment are not well established. METHODS: 675 participants with PD from the international Care of Late-Stage Parkinsonism (CLaSP) study were grouped into those without (n = 333, 49%) and with cognitive impairment (MMSE < 24/30 or diagnosis of dementia or Mild Cognitive Impairment; n = 342, 51%) and their clinical features, care needs and healthcare utilisation compared...
January 17, 2024: Journal of Geriatric Psychiatry and Neurology
https://read.qxmd.com/read/38227732/scam-susceptibility-thoughts-on-how-to-initially-approach-and-manage-patients-in-a-geriatric-psychiatry-setting
#34
JOURNAL ARTICLE
Weijiao Huang, Anne Carlew, Collin Vas, Izabella De Abreu
Recent studies have demonstrated that older adults are more vulnerable to scams because of social isolation, economic affluence, mental disorders, struggles with technology, and cognitive impairments. In this report, we present the case of a 73-year-old man who fell victim to multiple scams over 8 years, leading to a loss of more than $100,000. We also discuss approaches to managing such patients in the outpatient setting. Susceptibility to scams is considered an increasing threat to the well-being of aging societies...
January 1, 2024: Journal of Psychiatric Practice
https://read.qxmd.com/read/38226028/impact-of-virtual-reality-mental-health-nursing-simulation-on-nursing-students-competence
#35
JOURNAL ARTICLE
Geun Myun Kim, Ji Young Lim, Eun Joo Kim, Mijung Yeom
PURPOSE: This study investigates the impact of a Virtual Reality (VR)-based Mental Health Nursing Practice Simulation (MHNPS) on nursing students' competency in caring for individuals with mental disorders. Nursing students often face fear, anxiety, and helplessness during mental health (MH) rotations, impeding the attainment of learning objectives in the MH nursing practicum. Therefore, innovative strategies offering practice opportunities are crucial for their competence development...
2024: Journal of Multidisciplinary Healthcare
https://read.qxmd.com/read/38216887/psychiatric-disorders-in-older-adults-with-cancer-referred-to-psycho-oncology-service-in-a-tertiary-care-cancer-centre-a-7-year-real-world-experience-from-india
#36
JOURNAL ARTICLE
Jayita K Deodhar, Lekhika N Sonkusare, Savita S Goswami
BACKGROUND: Cancer affects mental health in older adults with cancer (OAC), affecting almost 50% of the patients. There are only a few studies on psychiatric disorders in OAC, especially in low resource settings. We report on our real-world experience of prevalence of and factors associated with psychiatric disorders in OAC referred to a psycho-oncology service in an Indian tertiary care cancer institute. METHODS: We retrospectively analysed medical and psycho-oncology records of patients aged 60 + on cancer-directed treatment or follow-up for < 2 years after treatment completion, referred to psycho-oncology services in a tertiary care cancer centre in Mumbai, India, from Jan 2011-Dec 2017...
January 12, 2024: BMC Psychiatry
https://read.qxmd.com/read/38204178/examining-the-new-consensus-criteria-for-traumatic-encephalopathy-syndrome-in-community-dwelling-older-adults
#37
JOURNAL ARTICLE
Douglas P Terry, Jacob Jo, Kristen Williams, Philip Davis, Grant L Iverson, Scott L Zuckerman
In 2021, an expert panel of clinician-scientists published the first consensus research diagnostic criteria for traumatic encephalopathy syndrome (TES), a clinical condition thought to be associated with chronic traumatic encephalopathy neuropathological change. This study evaluated the TES criteria in older adults and assessed associations between TES criteria and a history of repetitive head impacts. This cross-sectional, survey-based study examined the symptoms of TES, previous repetitive head impacts, and a variety of current health difficulties...
January 24, 2024: Journal of Neurotrauma
https://read.qxmd.com/read/38171949/deltascan-for-the-assessment-of-acute-encephalopathy-and-delirium-in-icu-and-non-icu-patients-a-prospective-cross-sectional-multicenter-validation-study
#38
JOURNAL ARTICLE
Fienke L Ditzel, Suzanne C A Hut, Mark van den Boogaard, Michel Boonstra, Frans S S Leijten, Evert-Jan Wils, Tim van Nesselrooij, Marjan Kromkamp, Paul J T Rood, Christian Röder, Paul F Bouvy, Michiel Coesmans, Robert Jan Osse, Monica Pop-Purceleanu, Edwin van Dellen, Jaap W M Krulder, Koen Milisen, Richard Faaij, Ariël M Vondeling, Ad M Kamper, Barbara C van Munster, Annemarieke de Jonghe, Marian A M Winters, Jeanette van der Ploeg, Sanneke van der Zwaag, Dineke H L Koek, Clara A C Drenth-van Maanen, Albertus Beishuizen, Deirdre M van den Bos, Wiepke Cahn, Ewoud Schuit, Arjen J C Slooter
OBJECTIVES: To measure the diagnostic accuracy of DeltaScan: a portable real-time brain state monitor for identifying delirium, a manifestation of acute encephalopathy (AE) detectable by polymorphic delta activity (PDA) in single-channel electroencephalograms (EEGs). DESIGN: Prospective cross-sectional study. SETTING: Six Intensive Care Units (ICU's) and 17 non-ICU departments, including a psychiatric department across 10 Dutch hospitals. PARTICIPANTS: 494 patients, median age 75 (IQR:64-87), 53% male, 46% in ICUs, 29% delirious...
December 9, 2023: American Journal of Geriatric Psychiatry
https://read.qxmd.com/read/38171638/ertapenem-induced-encephalopathy-in-a-patient-with-liver-abscess-and-acute-kidney-injury
#39
JOURNAL ARTICLE
Shahid Farooq, Allan Acosta
A man in his late 70s, retired and independent, generally fit and well with a history of normal cognitive function baseline presented with liver abscess and acute kidney injury. He received meropenem 1 g three times a day for 15 days then subsequently changed to ertapenem 1 g one time a day in preparation for outpatient antibiotic treatment. After 2 days of starting ertapenem, the patient developed night-time delirium, decreased orientation and insomnia, loss of appetite, jerking and hallucination. Investigations have been done to investigate the cause of acute delirium, including lumbar puncture, CT brain, MRI brain, repeat CT abdomen and pelvis to monitor the liver abscess, and electroencephalogram but results were all unremarkable...
January 3, 2024: BMJ Case Reports
https://read.qxmd.com/read/38156879/the-discontinuity-hypothesis-of-depression-in-later-life-clinical-and-research-implications
#40
JOURNAL ARTICLE
Richard C Oude Voshaar
The term depression is overused as an umbrella term for a variety of conditions, including depressed mood and various psychiatric disorders. According to psychiatric diagnostic criteria, depressive disorders impact nearly all aspects of human life and are a leading cause of disability worldwide. The widespread assumption that different types of depression lie on a continuum of severity has stimulated important research on subthreshold depression in later life. This view assumes that depressed mood is a precursor of a depressive disorder...
December 1, 2023: Age and Ageing
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