keyword
MENU ▼
Read by QxMD icon Read
search

Node

keyword
https://www.readbyqxmd.com/read/28813099/leaf-area-estimation-of-cassava-from-linear-dimensions
#1
Samara Zanetti, Laís F M Pereira, Maria Márcia P Sartori, Marcelo A Silva
The objective of this study was to determine predictor models of leaf area of ​​cassava from linear leaf measurements. The experiment was carried out in greenhouse in the municipality of Botucatu, São Paulo state, Brazil. The stem cuttings with 5-7 nodes of the cultivar IAC 576-70 were planted in boxes filled with about 320 liters of soil, keeping soil moisture at field capacity, monitored by puncturing tensiometers. At 80 days after planting, 140 leaves were randomly collected from the top, middle third and base of cassava plants...
August 14, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28813029/joint-mobile-data-collection-and-wireless-energy-transfer-in-wireless-rechargeable-sensor-networks
#2
Ping Zhong, Ya-Ting Li, Wei-Rong Liu, Gui-Hua Duan, Ying-Wen Chen, Neal Xiong
In wireless rechargeable sensor networks (WRSNs), there is a way to use mobile vehicles to charge node and collect data. It is a rational pattern to use two types of vehicles, one is for energy charging, and the other is for data collecting. These two types of vehicles, data collection vehicles (DCVs) and wireless charging vehicles (WCVs), are employed to achieve high efficiency in both data gathering and energy consumption. To handle the complex scheduling problem of multiple vehicles in large-scale networks, a twice-partition algorithm based on center points is proposed to divide the network into several parts...
August 16, 2017: Sensors
https://www.readbyqxmd.com/read/28813024/advances-in-understanding-of-penile-carcinogenesis-the-search-for-actionable-targets
#3
REVIEW
Juan Chipollini, Sharon Chaing, Mounsif Azizi, Laura C Kidd, Patricia Kim, Philippe E Spiess
Penile cancer (PeCa) is a rare malignancy with potentially devastating effects. Squamous cell carcinoma is the most common variant with distinct precancerous lesions before development into invasive disease. Involvement of the inguinal lymph nodes is the most important prognostic factor in PeCa, and once disease is present outside the groin, prognosis is poor. Metastatic PeCa is challenging to treat and often requires multidisciplinary approaches in management. Due to its rarity, molecular understanding of the disease continues to be limited with most studies based on small, single center series...
August 16, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28812274/oxytocin-and-anxiety-disorders
#4
Michael G Gottschalk, Katharina Domschke
In the present chapter, we review the literature focusing on oxytocin (OT)-centered research in anxiety spectrum conditions, comprising separation anxiety disorder, specific phobias, social anxiety disorder (SAD), panic disorder, generalized anxiety disorder, and anxiety-related endophenotypes (e.g., trust behavior, behavioral inhibition, neuroticism, and state/trait anxiety). OT receptor gene (OXTR) polymorphisms have been implicated in gene-environment interactions with attachment style and childhood maltreatment and to influence clinical outcomes, including SAD intensity and limbic responsiveness...
August 16, 2017: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/28812220/sphingosine-1-phosphate-receptor-modulators-for-the-treatment-of-multiple-sclerosis
#5
REVIEW
Burhan Z Chaudhry, Jeffrey A Cohen, Devon S Conway
Sphingosine 1-phosphate receptor (S1PR) modulators possess a unique mechanism of action in the treatment of multiple sclerosis (MS). Subtype 1 of the S1PR is expressed on the surface of lymphocytes and is important in regulating egression from lymph nodes. The S1PR modulators indirectly antagonize the receptor's function leading to sequestration of lymphocytes in the lymph nodes. Fingolimod was the first S1PR modulator to receive regulatory approval for relapsing-remitting MS after 2 phase III trials demonstrated potent efficacy, safety, and tolerability...
August 15, 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/28812120/risk-adapted-robotic-stereotactic-body-radiation-therapy-for-inoperable-early-stage-non-small-cell-lung-cancer
#6
Susanne Temming, Martin Kocher, Erich Stoelben, Lars Hagmeyer, De-Hua Chang, Konrad Frank, Khosro Hekmat, Juergen Wolf, Wolfgang W Baus, Robert Semrau, Christian Baues, S Marnitz
PURPOSE: To evaluate efficacy and toxicity of stereotactic body radiation therapy (SBRT) with CyberKnife® (Accuray, Sunnyvale, CA, USA) in a selected cohort of primary, medically inoperable early-stage non-small cell lung cancer (NSCLC) patients. METHODS: From 2012 to 2016, 106 patients (median age 74 years, range 50-94 years) with primary NSCLC were treated with SBRT using CyberKnife®. Histologic confirmation was available in 87 patients (82%). For mediastinal staging, 92 patients (87%) underwent (18)F-fluorodeoxyglucose positron-emission tomography (18-FDG-PET) and/or endobronchial ultrasound (EBUS)-guided lymph node biopsy or mediastinoscopy...
August 15, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28811897/impact-of-in-vitro-chemosensitivity-test-guided-platinum-based-adjuvant-chemotherapy-on-the-surgical-outcomes-of-patients-with-p-stage-iiia-non-small-cell-lung-cancer-that-underwent-complete-resection
#7
Yuki Akazawa, Masahiko Higashiyama, Kazumi Nishino, Jyunji Uchida, Toru Kumagai, Takako Inoue, Ayako Fujiwara, Toshiteru Tokunaga, Jiro Okami, Fumio Imamura, Ken Kodama, Hisayuki Kobayashi
The impact of in vitro chemosensitivity test-guided platinum-based adjuvant chemotherapy on the surgical outcomes of patients undergoing complete resection for locally advanced non-small cell lung cancer (NSCLC) has yet to be elucidated. In the present study, the utility of adjuvant chemotherapy based on the collagen gel droplet embedded culture drug sensitivity test (CD-DST) in patients with p (pathology)-stage IIIA NSCLC was retrospectively analyzed. A series of 39 patients that had received platinum-based adjuvant chemotherapy following complete resection between 2007 and 2012 were enrolled...
September 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28811578/an-epithelial-to-mesenchymal-transition-inducing-potential-of-granulocyte-macrophage-colony-stimulating-factor-in-colon-cancer
#8
Yaqiong Chen, Zhi Zhao, Yu Chen, Zhonglin Lv, Xin Ding, Renxi Wang, He Xiao, Chunmei Hou, Beifen Shen, Jiannan Feng, Renfeng Guo, Yan Li, Hui Peng, Gencheng Han, Guojiang Chen
Growing evidence shows that granulocyte macrophage colony-stimulating factor (GM-CSF) has progression-promoting potentials in certain solid tumors, which is largely attributed to the immunomodulatory function of this cytokine in tumor niches. However, little is known about the effect of GM-CSF on cancer cells. Herein, we show that chronic exposure of colon cancer cells to GM-CSF, which harbor its receptor, leads to occurrence of epithelial to mesenchymal transition (EMT), in time and dose-dependent manners...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28811334/argonaute-8-ago8-mediates-the-elicitation-of-primary-defense-against-herbivory
#9
Maitree Pradhan, Priyanka Pandey, Klaus Gase, Murali Shraff, Ravi K Singh, Avinash Sethi, Ian T Baldwin, Shree P Pandey
In Nicotiana attenuata, specific RNA directed RNA polymerase (RdR1) and the Dicer-like proteins (DCL3 and 4) are recruited during herbivore attack to mediate the regulation of defense responses. However, the identity and role(s) of Argonautes (AGOs) involved in herbivory remains unknown. Of the 11 AGOs in the N. attenuata genome, we silenced the expression of 10. Plants silenced in NaAGO8 expression grew normally but were highly susceptible to herbivore attack. Larvae of the Manduca sexta grew faster when consuming irAGO8 plants, but did not differ from WT when consuming plants silenced in AGO1 (a, b and c), AGO2, AGO4 (a and b), AGO7, or AGO10 expression...
August 15, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28810933/microrna-152-suppresses-human-osteosarcoma-cell-proliferation-and-invasion-by-targeting-e2f-transcription-factor-3
#10
Chao Ma, Jinfeng Han, Dong Dong, Nanya Wang
MicroRNA-152(miR-152) expression has been reported to be downregulated in osteosarcoma (OS). However, the role of miR-152 in OS is not well documented. In the present study, we aim to explore the function and underlying mechanism of miR-152 in OS. We found that miR-152 was underexpressed in OS tissues and cell lines. Decreased miR-152 was inversely correlated with lymph-node metastasis and advanced clinical stage. Overexpression of miR-152 significantly inhibited cell proliferation, colony formation, migration and invasion of OS cells...
August 15, 2017: Oncology Research
https://www.readbyqxmd.com/read/28810927/stat3-mediated-upregulation-of-lncrna-hoxd-as1-as-a-cerna-facilitates-liver-cancer-metastasis-by-regulating-sox4
#11
Hui Wang, Xisong Huo, Xin-Rong Yang, Jia He, Lijun Cheng, Na Wang, Xuan Deng, Haojie Jin, Ning Wang, Cun Wang, Fangyu Zhao, Jingyuan Fang, Ming Yao, Jia Fan, Wenxin Qin
BACKGROUND: Several of the thousands of human long noncoding RNAs (lncRNAs) have been functionally characterized, yet their potential involvement in hepatocellular carcinoma (HCC) remains poorly understood. METHODS: LncRNA-HOXD-AS1 was identified by microarray and validated by real-time PCR. The clinicopathological significance of HOXD-AS1 was analyzed by Kaplan-Meier method. Chromatin immunoprecipitation was conducted to examine the mechanism of HOXD-AS1 upregulation...
August 14, 2017: Molecular Cancer
https://www.readbyqxmd.com/read/28810922/pleural-epithelioid-angiosarcoma-with-lymphatic-differentiation-arisen-after-radiometabolic-therapy-for-thyroid-carcinoma-immunohistochemical-findings-and-review-of-the-literature
#12
REVIEW
Daniela Cabibi, Giulia Pipitone, Rossana Porcasi, Sabrina Ingrao, Ignazio Benza, Calogero Porrello, Massimo Cajozzo, Antonino Giulio Giannone
BACKGROUND: Pleural angiosarcoma is a rare tumor that causes diffuse pleural thickening and effusion, mimicking mesothelioma. Immunohistochemistry is needed to highlight endothelial differentiation. We describe the first case of pleural angiosarcoma with lymphatic differentiation following radiometabolic therapy for thyroid carcinoma. CASE PRESENTATION: A 50-year-old man showed diffuse pleural thickening and effusion. Nine years earlier, he underwent thyroidectomy and radiometabolic therapy for thyroid carcinoma with lymph node metastases...
August 15, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/28810883/treatment-of-localized-gastric-and-gastroesophageal-adenocarcinoma-the-role-of-accurate-staging-and-preoperative-therapy
#13
REVIEW
Brian Badgwell, Prajnan Das, Jaffer Ajani
Gastric cancer is the third most common cause of cancer death worldwide, although it is not in the top 10 causes of cancer death in Northern America. Due to clear differences in incidence, screening, risk factors, tumor biology, and treatment between gastric cancers from Eastern and Western countries, our treatment is primarily guided by trials from Western countries. Patients undergo an extensive staging evaluation including high-quality CT imaging, endoscopic ultrasound, and diagnostic laparoscopy with peritoneal washings for cytology...
August 15, 2017: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/28810868/nontuberculosis-mycobacteria-are-the-major-causes-of-tuberculosis-like-lesions-in-cattle-slaughtered-at-bahir-dar-abattoir-northwestern-ethiopia
#14
Anwar Nuru, Aboma Zewude, Temesgen Mohammed, Biniam Wondale, Laikemariam Teshome, Muluwork Getahun, Gezahegne Mamo, Girmay Medhin, Rembert Pieper, Gobena Ameni
BACKGROUND: The main cause of bovine tuberculosis (bTB) is believed to be Mycobacterium bovis (M. bovis). Nontuberculosis mycobacteria (NTM) are neglected but opportunistic pathogens and obstacles for bTB diagnosis. This study aimed to isolate and characterize the mycobacteria organisms involved in causing TB-like lesions in cattle in northwestern Ethiopia. RESULTS: A total of 2846 carcasses of cattle were inspected for TB lesions. Ninety six tissues (including lymph nodes such as submandibular, retropharyngeal, tonsilar, mediatinal, bronchial and mesenteric, and organs such as lung, liver and kidney) with suspicious TB lesion(s) were collected and cultured on Lowenstein-Jensen medium...
August 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28810829/blocking-il-10-signalling-at-the-time-of-immunization-does-not-increase-unwanted-side-effects-in-mice
#15
Guoying Ni, Zaowen Liao, Shu Chen, Tianfang Wang, Jianwei Yuan, Xuan Pan, Kate Mounsey, Shelley Cavezza, Xiaosong Liu, Ming Q Wei
BACKGROUND: Cancer therapeutic vaccine induced cytotoxic T cell (CTL) responses are pivotal for the killing of tumour cells. Blocking interleukin 10 (IL-10) signalling at the time of immunization increases vaccine induced CTL responses and improves prevention of tumour growth in animal models compared to immunization without an IL-10 signalling blockade. Therefore, this immunization strategy may have potential to curtail cancer in a clinical setting. However, IL-10 deficiency leads to autoimmune disease in the gut...
August 15, 2017: BMC Immunology
https://www.readbyqxmd.com/read/28810826/improving-fold-resistance-prediction-of-hiv-1-against-protease-and-reverse-transcriptase-inhibitors-using-artificial-neural-networks
#16
Olivier Sheik Amamuddy, Nigel T Bishop, Özlem Tastan Bishop
BACKGROUND: Drug resistance in HIV treatment is still a worldwide problem. Predicting resistance to antiretrovirals (ARVs) before starting any treatment is important. Prediction accuracy is essential, as low-accuracy predictions increase the risk of prescribing sub-optimal drug regimens leading to patients developing resistance sooner. Artificial Neural Networks (ANNs) are a powerful tool that would be able to assist in drug resistance prediction. In this study, we constrained the dataset to subtype B, sacrificing generalizability for a higher predictive performance, and demonstrated that the predictive quality of the ANN regression models have definite improvement for most ARVs...
August 15, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28810629/inhibition-of-microrna-34a-ameliorates-murine-collagen-induced-arthritis
#17
Qiujie Dang, Fan Yang, Hongwei Lei, Xin Liu, Minglu Yan, He Huang, Xuemei Fan, Yang Li
Rheumatoid arthritis (RA) is one of the most frequently occurring autoimmne diseases, with symptoms including synovium hyperplasia, immune disorder, cartilage damage and bone resorption. It has previously been demonstrated that microRNA-34a (miR-34a) may participate in cell apoptosis, immune activation and bone metabolism, therefore the present study investigated the effects of miR-34a on RA. Collagen-induced arthritic (CIA) mice were employed as a murine model of experimental arthritis, and it was demonstrated that the level of miR-34a in the spleens, lymph nodes and synovium was increased in the CIA mice compared with normal DBA/1j mice...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28810582/microrna-92a-promotes-cell-viability-and-invasion-in-cervical-cancer-via-directly-targeting-dickkopf-related-protein-3
#18
Shengtian Luo, Na Li, Shaohua Yu, Lichun Chen, Chunying Liu, Jiawei Rong
MicroRNA-92a (miR-92a) was recently reported to have an oncogenic role in cervical cancer; however, the underlying mechanism remains largely unclear. The present study aimed to investigate the expression, clinical significance and regulatory mechanism of miR-92a in cervical cancer. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) data indicated that miR-92a was significantly upregulated in cervical cancer tissues compared with matched adjacent non-tumor tissues (P<0.01). High expression of miR-92a was significantly associated with poor differentiation (P=0...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28810559/identification-of-key-genes-and-pathways-associated-with-obesity-in-children
#19
Ling Li, Guangyu Wang, Ning Li, Haiyan Yu, Jianping Si, Jiwen Wang
The present study aimed to identify potential key genes and pathways in obese children in order to explore possible molecular mechanisms associated with child obesity. The array dataset GSE29718 was downloaded from the Gene Expression Omnibus database. Subcutaneous adipose tissue samples derived from 7 obese children and 8 lean children were selected for the analysis. Differentially expressed genes (DEGs) in samples from obese children compared with those from lean children were analyzed by the limma package...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28810556/mir-187-inhibits-tumor-growth-and-invasion-by-directly-targeting-mapk12-in-osteosarcoma
#20
Chengliang Cui, Xiaoyu Shi
MicroRNAs (miRNAs/miRs) play crucial roles in cancer development and progression. The purposes of this study were to investigate the role of miR-187 in osteosarcoma and clarify the regulation of MAPK12 by miR-187. Quantitative polymerase chain reaction was used to examine miR-187 expression in osteosarcoma tissues and cell lines. The clinicopathological significance of miR-187 downregulation was further analyzed. Transwell migration and invasion assays were performed. A luciferase reporter assay was conducted to confirm the target gene of miR-187, and the results were validated in cervical cancer tissues and cell lines...
August 2017: Experimental and Therapeutic Medicine
keyword
keyword
89472
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"