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amebic liver abscess

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https://www.readbyqxmd.com/read/29201778/liver-disease-in-sri-lanka
#1
REVIEW
Hasitha S Wijewantha
Liver disease in Sri Lanka is mainly due to alcoholic liver disease and nonalcoholic fatty liver disease. In contrast to other South Asian countries, the prevalence of hepatitis B and C is low in Sri Lanka and prevalence of hepatitis A is intermediate. The few reported cases of hepatitis E in Sri Lanka are mainly in people who have traveled to neighboring South Asian countries. Wilson's disease, autoimmune hepatitis, hemochromatosis, drug-induced liver disease, and primary biliary cirrhosis are recognized causes of liver disease in Sri Lanka...
January 2017: Euroasian Journal of Hepato-Gastroenterology
https://www.readbyqxmd.com/read/29201767/management-of-liver-abscess-in-children-our-experience
#2
Mukta Waghmare, Hemanshi Shah, Charu Tiwari, Kiran Khedkar, Suraj Gandhi
Introduction: Liver abscess is common in pediatric population in India. Children have unique set of predisposing factors and clinical features. Liver abscesses are infectious, space-occupying lesions in the liver; the two most common abscesses being pyogenic and amebic. Its severity depends on the source of the infection and the underlying condition of the patient. Materials and methods: A total of 34 patients less than 12 years were assessed in a retrospective study from January 2012 to 2016...
January 2017: Euroasian Journal of Hepato-Gastroenterology
https://www.readbyqxmd.com/read/29185982/adrenergic-regulation-during-acute-hepatic-infection-with-entamoeba-histolytica-in-the-hamster-involvement-of-oxidative-stress-nrf2-and-nf-kappab
#3
Liseth Rubi Aldaba-Muruato, Martín Humberto Muñoz-Ortega, José Roberto Macías-Pérez, Julieta Pulido-Ortega, Sandra Luz Martínez-Hernández, Javier Ventura-Juárez
Oxidative stress and transcriptional pathways of nuclear factor erythroid 2-related factor 2 (Nrf2) and nuclear factor kappa-B (NF-κB) are critically involved in the etiopathology of amebic liver abscess (ALA). In this work, we studied the relationship between the adrenergic nervous system and ALA in the hamster. ALA was visible at 12 h of infection. While 6-hydroxidopamine (6-OHDA) decreased infection, propranolol (β-adrenergic blocker) treatment was associated with less extensive liver damage, and phentolamine treatment (α-adrenergic blocker) significantly reduced ALA compared to 6-OHDA and propranolol...
2017: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/29033682/usefulness-of-tc99m-mebrofenin-hepatobiliary-scintigraphy-and-single-photon-emission-computed-tomography-computed-tomography-in-the-diagnosis-of-bronchobiliary-fistula
#4
Rahul Vithalrao Parghane, Rohit Kumar Phulsunga, Rajesh Gupta, Rajender Kumar Basher, Anish Bhattacharya, Bhagwant Rai Mittal
Bronchobiliary fistula (BBF), a rare complication of liver disease, is an abnormal communication between the biliary tract and bronchial tree. BBF may occur as a consequence of local liver infections such as hydatid or amebic disease, pyogenic liver abscess or trauma to the liver, obstruction of biliary tract, and tumor. As such management of liver disease with BBF is very difficult and often associated with a high rate of morbidity and mortality. Therefore, timely diagnosis of BBF is imperative. Hepatobiliary scintigraphy along with hybrid single photon emission computed tomography/computed tomography using Tc99m-mebrofenin is a very useful noninvasive imaging modality, in the diagnosis of BBF...
October 2017: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28851845/inhibition-of-amebic-lysosomal-acidification-blocks-amebic-trogocytosis-and-cell-killing
#5
Allissia A Gilmartin, Katherine S Ralston, William A Petri
Entamoeba histolytica ingests fragments of live host cells in a nibbling-like process termed amebic trogocytosis. Amebic trogocytosis is required for cell killing and contributes to tissue invasion, which is a hallmark of invasive amebic colitis. Work done prior to the discovery of amebic trogocytosis showed that acid vesicles are required for amebic cytotoxicity. In the present study, we show that acidified lysosomes are required for amebic trogocytosis and cell killing. Interference with lysosome acidification using ammonium chloride, a weak base, or concanamycin A, a vacuolar H(+) ATPase inhibitor, decreased amebic trogocytosis and amebic cytotoxicity...
August 29, 2017: MBio
https://www.readbyqxmd.com/read/28413289/intra-operative-mechanical-ventilation-in-amebic-liver-abscess-surgery-another-paradigm
#6
Aanchal Kakkar, Asha Tyagi, Ashok Kumar Sethi
No abstract text is available yet for this article.
January 2017: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/28348756/amoeboma-in-a-saudi-resident-a-case-report
#7
Sanaa Al Rehily, Reham Kaki, Fahad Al Ghamdi, Dalia El-Hossary
INTRODUCTION: Amoebiasis is the third most frequent cause of mortality after malaria and schistosomiasis. In developed countries, amebiasis is also seen in migrants who have travelled to endemic areas. The factors responsible for its progression from intestinal amebiasis to an amebic liver abscess are not fully understood. CASE PRESENTATION: A 54-year-old man presented with abdominal pain, fever and diarrhoea. Laparotomy confirmed an inflammatory mass involving the right colon, and he underwent a right hemicolectomy...
June 2016: JMM Case Reports
https://www.readbyqxmd.com/read/28217619/diagnostic-difficulty-of-liver-lesion
#8
Jayabal Pandiaraja
Liver abscess is mostly either pyogenic or amebic. Fungal and mycobacterial liver abscesses are rare and mostly associated with immunosuppression. The occurrence of fungal liver abscess with hydatid cyst was never reported previously. This case created diagnostic difficulty, whether we are dealing with liver abscess or hydatid cyst. Sometimes, it may be possible that concurrent occurrence of hydatid cyst with liver abscess or hydatid cyst become infected and mimic like liver abscess.
July 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28127209/areas-of-research-and-clinical-approaches-to-the-study-of-liver-abscess
#9
Gregorio González-Alcaide, Jorge Peris, José Manuel Ramos
AIM: To analyze the research activity on liver abscess (LA) and identify the main topic clusters in the area. METHODS: We identified all documents using the medical subject heading "LA" indexed in the MEDLINE database between 2001 and 2015. We performed a descriptive bibliometric analysis, characterizing the evolution of scientific activity, the publication types of the documents, the document categories of clinical interest (case reports, clinical trials, evaluation studies, meta-analysis, observational studies, practice guidelines and validation studies) and the geographic distribution of the research...
January 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27756400/recurrent-amebic-liver-abscesses-over-a-16-year-period-a-case-report
#10
D Creemers-Schild, P J J van Genderen, L G Visser, J J van Hellemond, P J Wismans
BACKGROUND: Amebic liver abscess is a rare disease in high-income countries. Recurrence of amebic liver abscess is even rarer with only a few previous reports. Here we present a patient who developed three subsequent amebic liver abscesses over a sixteen-year period. CASE PRESENTATION: A Caucasian male developed recurrent amebic liver abscesses, when aged 23, 27 and 39 years. Only on the first occasion did this coincide with a recent visit to the tropics. The patient received adequate treatment during each episode...
October 18, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27663892/role-of-ehrab7a-in-phagocytosis-of-type-1-fimbriated-e-coli-by-entamoeba-histolytica
#11
Kuldeep Verma, Tomoyoshi Nozaki, Sunando Datta
Entamoeba histolytica, the causative agent of amoebic colitis and liver abscess in human, ingests the intestinal bacteria and variety of host cells. Phagocytosis of bacteria by the amebic trophozoite has been reported to be important for the virulence of the parasite. Here, we set out to characterize different stages of phagocytosis of type 1 E. coli and investigated the role of a set of amoebic Rab GTPases in the process. The localizations of the Rab GTPases during different stages of the phagocytosis were investigated using laser scanning confocal microscopy and their functional relevance were determined using fluorescence activated cell sorter based assay as well as colony forming unit assay...
December 2016: Molecular Microbiology
https://www.readbyqxmd.com/read/27616150/entamoeba-histolytica-overexpression-of-the-gal-galnac-lectin-ehcp2-and-ehcp5-genes-in-an-in-vivo-model-of-amebiasis
#12
Virginia Sánchez, Jesús Serrano-Luna, Esther Ramírez-Moreno, Víctor Tsutsumi, Mineko Shibayama
The parasite Entamoeba histolytica causes intestinal amebiasis and amebic liver abscess as its main extraintestinal manifestation. To study the in vivo events related to inflammation and the interactions between hosts and parasites during amebiasis, we designed a novel model of host-parasite interactions using cellulose membrane dialysis bags containing E. histolytica trophozoites. A bag is placed into the hamster peritoneal cavity, as has been reported in previous studies of programmed cell death (PCD) in E...
December 2016: Parasitology International
https://www.readbyqxmd.com/read/27540556/community-acquired-methicillin-resistant-pyogenic-liver-abscess-a-case-report
#13
Joel Cherian, Rahul Singh, Muralidhar Varma, Sudha Vidyasagar, Chiranjay Mukhopadhyay
Pyogenic liver abscesses are rare with an incidence of 0.5% to 0.8% and are mostly due to hepatobiliary causes (40% to 60%). Most are polymicrobial with less than 10% being caused by Staphylococcus aureus. Of these, few are caused by methicillin-resistant Staphylococcus aureus (MRSA) and fewer still by a community-acquired strain. Here we present a case study of a patient with a community-acquired MRSA liver abscess. The patient presented with fever since 1 month and tender hepatomegaly. Blood tests revealed elevated levels of alkaline phosphatase, C-reactive protein, erythrocyte sedimentation rate, and neutrophilic leukocytosis...
July 2016: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/27525214/the-intestinal-bacterial-microbiome-and-e-histolytica-infection
#14
REVIEW
Stacey L Burgess, William A Petri
Entamoeba histolytica, the etiological agent of amebiasis, is a significant cause of pediatric diarrhea in South Asia and sub-Saharan Africa. The clinical outcome of an E. histolytica exposure varies enormously and can present as diarrhea, dysentery, or amebic liver abscess. Host and parasite factors likely contribute to the outcome of infection with the parasite, but do not explain the wide variation in presentation of disease. This suggests that other environmental factors affect disease. An emerging body of work suggests that the host intestinal bacterial microbiome may have a significant influence on the development and outcome of amebiasis...
2016: Current Tropical Medicine Reports
https://www.readbyqxmd.com/read/27509703/efficacy-of-aspiration-in-amebic-liver-abscess
#15
RANDOMIZED CONTROLLED TRIAL
Jayant Kumar Ghosh, Sundeep Kumar Goyal, Manas Kumar Behera, Manish Kumar Tripathi, Vinod Kumar Dixit, Ashok Kumar Jain, Ramchandra Shukla
BACKGROUND: Amebic liver abscess (ALA) is a common and serious problem in our country. There are only a few controlled trials on the efficacy and advantages of combination therapy with percutaneous needle aspiration and pharmacotherapy, over pharmacotherapy alone for amebic liver abscess. MATERIAL AND METHODS: This study was conducted to compare the efficacy of two different treatment modalities i.e. drug treatment alone vs. drug treatment and aspiration of abscess cavity in patients with small (up to 5 cm) and large (5 cm to 10 cm) size ALA...
October 2015: Tropical Gastroenterology: Official Journal of the Digestive Diseases Foundation
https://www.readbyqxmd.com/read/27478673/primary-pulmonary-amebiasis-complicated-with-multicystic-empyema
#16
Ali Zakaria, Bayan Al-Share, Khaled Al Asad
Amebiasis is a parasitic infection caused by the protozoan Entamoeba histolytica. While most infections are asymptomatic, the disease could manifest clinically as amebic dysentery and/or extraintestinal invasion in the form of amebic liver abscess or other more rare manifestations such as pulmonary, cardiac, or brain involvement. Herein we are reporting a case of a 24-year-old male with history of Down syndrome who presented with severe right side pneumonia complicated with multicystic empyema resistant to regular medical therapy...
2016: Case Reports in Pulmonology
https://www.readbyqxmd.com/read/27029693/gastrointestinal-fistulization-in-amebic-liver-abscess
#17
K P Srikanth, B R Thapa, Sadhna B Lal
BACKGROUND: Liver abscess is a common deep seated abscess in children; amebic liver abscess is associated with more local complications. CASE CHARACTERISTICS: We report two preschool children presenting with short history of pain, fever and right upper quadrant pain. The abscess communicated with gastro-intestinal tract (ascending colon in case 1 and duodenum in case 2), and diagnosis of amebic liver abscess was confirmed by DNA PCR. OUTCOME: Both children were successfully managed with intravenous antibiotics and catheter drainage...
March 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/26998437/seroprevalence-of-entamoeba-histolytica-from-a-tertiary-care-hospital-south-india
#18
Sankaramoorthy Dhanalakshmi, Subhash Chandra Parija
INTRODUCTION: Amebiasis is the third leading cause of death after malaria and schistosomiasis. Diagnosis is based on microscopy, culture, isoenzyme analysis, and serology-based techniques. In resource-limited nation such as India where polymerase chain reaction cannot be employed, serology is considered to be the reliable diagnostic tool. To find the seroprevalence of Entamoeba histolytica IgG antibody by enzyme-linked immunosorbent assay (ELISA) among the liver abscess cases and healthy controls...
January 2016: Tropical Parasitology
https://www.readbyqxmd.com/read/26994772/gut-microbiome-diversity-in-acute-infective-and-chronic-inflammatory-gastrointestinal-diseases-in-north-india
#19
REVIEW
Saurabh Kedia, Ritika Rampal, Jaishree Paul, Vineet Ahuja
The disease profile in the Indian population provides a unique opportunity for studying the host microbiome interaction in both infectious (amebiasis) and autoimmune diseases like inflammatory bowel disease (IBD) from a similar environment and genetic background. Analysis of fecal samples from untreated amebic liver abscess (ALA) patients, Entamoeba histolytica (Eh)-negative and -positive asymptomatic individuals, and pus samples from naive ALA patients revealed a significant reduction in Lactobacillus in asymptomatic individuals (Eh +ve) and ALA patients...
July 2016: Journal of Gastroenterology
https://www.readbyqxmd.com/read/26928829/amebic-liver-abscess-in-israeli-travelers-a-retrospective-study
#20
Tamar Lachish, Anat Wieder-Finesod, Eli Schwartz
Amebic liver abscess (ALA) is endemic in developing countries. The epidemiology and clinical characteristics of the disease in developing countries are well described. Travelers from nonendemic countries can serve as a model for the natural history of ALA. Currently, the available literature on travelers is limited. This is a retrospective observational study on Israeli travelers diagnosed with ALA. Data regarding travel history, clinical presentation, imaging, and treatment were collected and analyzed. Among 6,867 ill returning Israeli travelers, amebiasis was diagnosed in 53 travelers (0...
May 4, 2016: American Journal of Tropical Medicine and Hygiene
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