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https://www.readbyqxmd.com/read/29132143/a-jurassic-gliding-euharamiyidan-mammal-with-an-ear-of-five-auditory-bones
#1
Gang Han, Fangyuan Mao, Shundong Bi, Yuanqing Wang, Jin Meng
Gliding is a distinctive locomotion type that has been identified in only three mammal species from the Mesozoic era. Here we describe another Jurassic glider that belongs to the euharamiyidan mammals and shows hair details on its gliding membrane that are highly similar to those of extant gliding mammals. This species possesses a five-boned auditory apparatus consisting of the stapes, incus, malleus, ectotympanic and surangular, representing, to our knowledge, the earliest known definitive mammalian middle ear...
November 13, 2017: Nature
https://www.readbyqxmd.com/read/29068074/the-anterior-process-of-the-malleus-in-extant-lagomorpha-mammalia
#2
Wolfgang Maier, Adrian Tröscher, Irina Ruf
The anterior anchoring of the malleus of 30 extant species of Lagomorpha (rabbits, hares, pikas) has been studied on the basis of histological serial sections and µCT-scans. It is shown that former studies of Oryctolagus, Lepus, and Ochotona are incomplete, because the rostral part of the processus anterior of the malleus is always lacking due to damage of this extremely delicate structure. Our study shows that in perinatal stages of Leporidae the praearticulare develops a prominent processus internus that fits into a groove at the ventral side of the tegmen tympani; this "tongue and groove"-arrangement may act as a hinge...
October 25, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28989763/into-the-dark-patterns-of-middle-ear-adaptations-in-subterranean-eulipotyphlan-mammals
#3
Daisuke Koyabu, Misato Hosojima, Hideki Endo
Evolution of the middle ear ossicles was a key innovation for mammals, enhancing the transmission of airborne sound. Radiation into various habitats from a terrestrial environment resulted in diversification of the auditory mechanisms among mammals. However, due to the paucity of phylogenetically controlled investigations, how middle ear traits have diversified with functional specialization remains unclear. In order to identify the respective patterns for various lifestyles and to gain insights into fossil forms, we employed a high-resolution tomography technique and compared the middle ear morphology of eulipotyphlan species (moles, shrews and hedgehogs), a group that has radiated into various environments, such as terrestrial, aquatic and subterranean habitats...
September 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28964300/anatomical-measurement-of-the-ossicles-in-patients-with-congenital-aural-atresia-and-stenosis
#4
Jieying Li, Keguang Chen, Chenlong Li, Dongming Yin, Tianyu Zhang, Peidong Dai
OBJECTIVES: Our aims were to measure and compare anatomical parameters of the ossicles in normal, congenital aural stenosis (CAS), and congenital aural atresia (CAA) ears. METHODS: This retrospective study was performed using three-dimensional reconstructed images derived from computed tomography scans of 20 normal subjects, 20 CAS patients, and 20 CAA patients. RESULTS: The lengths of the malleus handle and long process of the incus were greater in normal ears than in CAS and CAA ears (all P < 0...
October 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28959031/coup-tfii-is-required-for-morphogenesis-of-the-neural-crest-derived-tympanic-ring
#5
Wen-Hsin Hsu, Chun-Ming Chen, Li-Ru You
Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII) plays pivotal roles in cell growth, cell differentiation, and cell fate determination. Although genome-wide studies have identified COUP-TFII binding on gene sets mainly involved in neural crest cell (NCC) development and craniofacial morphogenesis, the direct functional connection between COUP-TFII and NCCs in vivo has not been well characterized. In this study, we show that COUP-TFII is expressed in the subpopulation of NCCs and its derivatives, and targeted ablation of COUP-TFII in mouse NCCs results in markedly shortened and bifurcated tympanic rings, which in turn disturb the caudal direction of external acoustic meatus invagination...
September 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28924582/data-on-the-effect-of-conductive-hearing-loss-on-auditory-and-visual-cortex-activity-revealed-by-intrinsic-signal-imaging
#6
Manuel Teichert, Jürgen Bolz
This data article provides additional data related to the research article entitled "Simultaneous intrinsic signal imaging of auditory and visual cortex reveals profound effects of acute hearing loss on visual processing" (Teichert and Bolz, 2017) [1]. The primary auditory and visual cortex (A1 and V1) of adult male C57BL/6J mice (P120-P240) were mapped simultaneously using intrinsic signal imaging (Kalatsky and Stryker, 2003) [2]. A1 and V1 activity evoked by combined auditory and visual stimulation were measured before and after conductive hearing loss (CHL) induced by bilateral malleus removal...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28855058/comparison-between-clinical-and-audiological-results-of-tympanoplasty-with-double-layer-graft-modified-sandwich-fascia-technique-and-single-layer-graft-underlay-fascia-and-underlay-cartilage-technique
#7
Sanjana Vijay Nemade, Kiran Jaywant Shinde, Pratibha Bharat Sampate
INTRODUCTION: Surgical repair of the tympanic membrane, termed a type one tympanoplasty is a tried and tested treatment modality. Overlay or underlay technique of tympanoplasty is common. Sandwich Tympanoplasty is the combined overlay and underlay grafting of tympanic membrane. OBJECTIVE: To describe and evaluate the modified sandwich graft (mediolateral double layer graft) tympanoplasty using temporalis fascia and areolar fascia. To compare the clinical and audiological outcome of modified sandwich tympanoplasty with underlay tympanoplasty...
August 27, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28852952/atlas-based-segmentation-of-temporal-bone-anatomy
#8
Kimerly A Powell, Tong Liang, Brad Hittle, Don Stredney, Thomas Kerwin, Gregory J Wiet
PURPOSE: To develop a time-efficient automated segmentation approach that could identify critical structures in the temporal bone for visual enhancement and use in surgical simulation software. METHODS: An atlas-based segmentation approach was developed to segment the cochlea, ossicles, semicircular canals (SCCs), and facial nerve in normal temporal bone CT images. This approach was tested in images of 26 cadaver bones (13 left, 13 right). The results of the automated segmentation were compared to manual segmentation visually and using DICE metric, average Hausdorff distance, and volume similarity...
November 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28846798/recognizing-malleus-fracture-in-a-woman-with-a-head-injury-after-a-fall
#9
Janet S Choi, Nathan Tu, John L Go, Elina Kari
No abstract text is available yet for this article.
August 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28812679/meckel-s-cartilage-breakdown-offers-clues-to-mammalian-middle-ear-evolution
#10
Neal Anthwal, Daniel J Urban, Zhe-Xi Luo, Karen E Sears, Abigail S Tucker
A key transformation in mammalian ear evolution was incorporation of the primary jaw joint of premammalian synapsids into the definitive mammalian middle ear of living mammals. This evolutionary transition occurred in two steps, starting with a partial or 'transitional' mammalian middle ear in which the ectotympanic and malleus were still connected to the mandible by an ossified Meckel's cartilage (MC), as observed in many Mesozoic mammals. This was followed by MC breakdown, freeing the ectotympanic and the malleus from the mandible and creating the definitive mammalian middle ear...
March 6, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28758555/sequential-motion-of-the-ossicular-chain-measured-by-laser-doppler-vibrometry
#11
Yasuomi Kunimoto, Kensaku Hasegawa, Shiro Arii, Hideyuki Kataoka, Hiroaki Yazama, Junko Kuya, Kazunori Fujiwara, Hiromi Takeuchi
OBJECTIVE: In order to help a surgeon make the best decision, a more objective method of measuring ossicular motion is required. METHODS: A laser Doppler vibrometer was mounted on a surgical microscope. To measure ossicular chain vibrations, eight patients with cochlear implants were investigated. To assess the motions of the ossicular chain, velocities at five points were measured with tonal stimuli of 1 and 3 kHz, which yielded reproducible results. The sequential amplitude change at each point was calculated with phase shifting from the tonal stimulus...
July 31, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28751512/flat-panel-angiography-in-the-cross-sectional-imaging-of-the-temporal-bone-assessment-of-image-quality-and-radiation-dose-compared-with-a-64-section-multisection-ct-scanner
#12
G Conte, E Scola, S Calloni, R Brambilla, M Campoleoni, L Lombardi, F Di Berardino, D Zanetti, L M Gaini, F Triulzi, C Sina
BACKGROUND AND PURPOSE: Cross-sectional imaging of the temporal bone is challenging because of the complexity and small dimensions of the anatomic structures. We evaluated the role of flat panel angiography in the cross-sectional imaging of the temporal bone by comparing its image quality and radiation dose with a 64-section multisection CT scanner. MATERIALS AND METHODS: We retrospectively collected 29 multisection CT and 29 flat panel angiography images of normal whole-head temporal bones...
July 27, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28719404/predictive-factors-for-hearing-outcomes-after-canaloplasty-in-patients-with-congenital-aural-atresia
#13
Jungmin Ahn, Sun Young Baek, Kyunga Kim, Yang-Sun Cho
OBJECTIVE: The aim of this study was to determine the most important factors in preoperative imaging, including components of Jahrsdoefer score (J score), and favorable prognostic factors for postoperative hearing results after canaloplasty for congenital aural atresia. STUDY DESIGN: Retrospective review of medical records. SETTING, PATIENTS, INTERVENTION, MAIN OUTCOME MEASURE: One hundred eight patients who underwent canaloplasty by a single surgeon between January 2011 and July 2014 were included...
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28711236/temporal-bone-computed-tomography-findings-associated-with-feasibility-of-endoscopic-ear-surgery
#14
Dunia Abdul-Aziz, Elliott D Kozin, Brian M Lin, Kevin Wong, Parth V Shah, Aaron K Remenschneider, Lukas D Landegger, Amy F Juliano, Michael S Cohen, Daniel J Lee
PURPOSE: There are no formal radiologic criteria to stratify patients for transcanal (TEES) or transmastoid endoscopic ear surgery for resection of cholesteatoma. We aim to determine 1) whether standard preoperative computed tomography (CT) findings are associated with the need for conversion to a transmastoid approach and 2) the amount of time added for conversion from TEES to transmastoid techniques. MATERIALS AND METHODS: Retrospective chart review of consecutive pediatric and adult cases of TEES for primary cholesteatoma from 2013 through 2015 (n=52)...
June 14, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28680629/an-isolated-traumatic-fracture-of-the-malleus-handle
#15
Sertac Yetiser
Traumatic fracture of the malleus handle without tympanic membrane perforation is a rare incidence. Diagnosis of conductive hearing loss can only be confirmed with manipulation of the ossicles under sedation as computerized tomography is not informative. We present a 39-year-old lady with Q-tip injury when she get sudden phone call.
July 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28680491/relation-between-ossicular-erosion-and-destruction-of-facial-and-lateral-semicircular-canals-in-chronic-otitis-media
#16
Suphi Bulğurcu, İlker Burak Arslan, Bünyamin Dikilitaş, İbrahim Çukurova
Introduction  Chronic otitis media can cause multiple middle ear pathogeneses. The surgeon should be aware of relation between ossicular chain erosion and other destructions because of the possibility of complications. Objective  This study aimed to investigate the rates of ossicular erosion in cases of patients with and without facial nerve canal destruction, who had undergone mastoidectomy due to chronic otitis media with or without cholesteatoma. Methods  We retrospectively analyzed three hundred twenty-seven patients who had undergone tympanomastoidectomy between April 2008 and February 2014...
July 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28666703/a-comparative-study-of-med-el-fmt-attachment-to-the-long-process-of-the-incus-in-intact-middle-ears-and-its-attachment-to-disarticulated-stapes-head
#17
Tao Chen, Liu-Jie Ren, Dong-Ming Yin, Jia Li, Lin Yang, Pei-Dong Dai, Tian-Yu Zhang
The Vibrant Soundbridge(©) (VSB) active middle-ear implant provides an effective treatment for mild-to-severe sensorineural hearing loss in the case of normal middle ear anatomy and mixed hearing loss in middle ear malformation. The VSB floating mass transducer (FMT), with proper couplers, can be installed on various structures of the ossicular chain, e.g., the short and long process of the incus, the stapes head, and the stapes footplate. A long process (LP) coupler is most commonly used for FMT attachment to the long process of the incus with intact ossicular chain, while CliP and Bell couplers are two standardized and reliable methods for FMT attachment to the stapes head with missing incus and malleus...
June 23, 2017: Hearing Research
https://www.readbyqxmd.com/read/28606657/the-effects-of-fibroblast-growth-factor-2-delivered-via-a-gelfoam-patch-on-the-regeneration-of-myringosclerotic-traumatic-eardrum-perforations-lying-close-to-the-malleus
#18
Zhong-Hai Jin, Yi-Han Dong, Zi-Han Lou
OBJECTIVE: We evaluated the effects of fibroblast growth factor-2 (FGF-2) delivered via a Gelfoam patch on the regeneration of myringosclerotic traumatic tympanic membrane perforations (TMPs) lying close to the malleus. STUDY DESIGN: A prospective, randomized, controlled clinical study. SETTING: A university-affiliated teaching hospital. SUBJECTS AND METHODS: We prospectively analyzed, in a randomized manner, the outcomes of treatment for traumatic TMPs constituting >25% of the tympanic membrane...
September 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28603080/a-novel-auditory-ossicles-membrane-and-the-development-of-conductive-hearing-loss-in-dmp1-null-mice
#19
Kun Lv, Haiyang Huang, Xing Yi, Mark E Chertoff, Chaoyuan Li, Baozhi Yuan, Robert J Hinton, Jian Q Feng
Genetic mouse models are widely used for understanding human diseases but we know much less about the anatomical structure of the auditory ossicles in the mouse than we do about human ossicles. Furthermore, current studies have mainly focused on disease conditions such as osteomalacia and rickets in patients with hypophosphatemia rickets, although the reason that these patients develop late-onset hearing loss is unknown. In this study, we first analyzed Dmp1 lac Z knock-in auditory ossicles (in which the blue reporter is used to trace DMP1 expression in osteocytes) using X-gal staining and discovered a novel bony membrane surrounding the mouse malleus...
October 2017: Bone
https://www.readbyqxmd.com/read/28601902/titanium-incus-interposition-ossiculoplasty-audiological-outcomes-and-extrusion-rates
#20
Selcuk Mulazimoglu, Alexander Saxby, Christoph Schlegel, Thomas Linder
This study aimed to evaluate the benefit but also the extrusions, dislocations, and failures of a titanium incus prosthesis along with the long-term audiological outcomes. We prospectively collected data from 139 patients undergoing ossiculoplasty using the Fisch titanium incus prosthesis between 2001 and 2016. Overall, 126 patients with at least 6 months of follow-up (mean 4.5 years, range 6-155 months) were analyzed. Patients were grouped as "extrusion" (n = 9, 7%) if the prosthesis extruded, "failure" (n = 22, 18%) if a reoperation was needed concerning the prosthesis, and "stable" (n = 95, 75%) if the prosthesis remained functional in the middle ear...
June 10, 2017: European Archives of Oto-rhino-laryngology
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