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Christian Güldner, Isabell Diogo, Eva Bernd, Stephanie Dräger, Magis Mandapathil, Afshin Teymoortash, Hesham Negm, Thomas Wilhelm
Cone beam computed tomography (CBCT, syn. digital volume tomography = DVT) was introduced into ENT imaging more than 10 years ago. The main focus was on imaging of the paranasal sinuses and traumatology of the mid face. In recent years, it has also been used in imaging of chronic ear diseases (especially in visualizing middle and inner ear implants), but an exact description of the advantages and limitations of visualizing precise anatomy in a relevant number of patients is still missing. The data sets of CBCT imaging of the middle and inner ear of 204 patients were analyzed regarding the visualization of 18 different anatomic structures...
October 17, 2016: European Archives of Oto-rhino-laryngology
H Kanon, M F Bhutta, J Lavy
The rate of revision stapes surgery is approximately 6% It is important that the appropriate instruments are available for surgery including pistons of varying sizes and diameters and a laser. The use of otomimix(®) cement is also helpful for incus reconstruction Patients should be carefully selected and appropriately counselled prior to surgery to address expectations Clinical outcomes from our series are comparable with the world wide literature Revision stapes surgery can be technically challenging and centres with more experience are likely to achieve better clinical outcomes This article is protected by copyright...
October 11, 2016: Clinical Otolaryngology
Ahmed Omran, Fatthi Abdel Baki, Ahmed Amin
OBJECTIVE: To assess the effectiveness of glass ionomer bone cement (GIBC) in lateral attic wall reconstruction after primary acquired attic cholesteatoma surgery. MATERIALS AND METHODS: This prospective study was conducted on twenty children collected from the ENT outpatient clinics of a secondary and tertiary hospital. All patients presented with chronic suppurative otitis media with cholesteatoma of the primary acquired attic type. All patients underwent intact canal wall mastoidectomy (ICWM) with a transcanal atticotomy to address primary cholesteatoma involving the attic and the supratubal recess...
August 2016: Journal of International Advanced Otology
Alexander Stoessel, Romain David, Philipp Gunz, Tobias Schmidt, Fred Spoor, Jean-Jacques Hublin
The diminutive middle ear ossicles (malleus, incus, stapes) housed in the tympanic cavity of the temporal bone play an important role in audition. The few known ossicles of Neandertals are distinctly different from those of anatomically modern humans (AMHs), despite the close relationship between both human species. Although not mutually exclusive, these differences may affect hearing capacity or could reflect covariation with the surrounding temporal bone. Until now, detailed comparisons were hampered by the small sample of Neandertal ossicles and the unavailability of methods combining analyses of ossicles with surrounding structures...
October 11, 2016: Proceedings of the National Academy of Sciences of the United States of America
Elke Loos, Nicolas Verhaert, Annelore Willaert, Koenraad Devriendt, Ann Swillen, Robert Hermans, Katya Op de Beeck, Greet Hens
The 22q11 deletion syndrome (22q11DS), the most frequent microdeletion syndrome in humans, presents with a large variety of abnormalities. A common abnormality is hearing impairment. The exact pathophysiological explanation of the observed hearing loss remains largely unknown. The aim of this study was to analyze the middle and inner ear malformations as seen on computer tomographic imaging in patients with 22q11DS. We retrospectively reviewed the charts of 11 22q11DS patients who had undergone a CT of the temporal bone in the past...
November 2016: American Journal of Medical Genetics. Part A
Kazuhiko Takeuchi, Masako Kitano, Hiroshi Sakaida, Sawako Masuda
The objective of this paper was to describe the clinical and otological findings in multiple members of a family with congenital glaucoma, cardiac anomaly, and conductive hearing loss due to ossicular chain anomalies. We performed a retrospective review of the medical charts and otological materials of multiple members of the same family. Congenital glaucoma and hearing loss were inherited by the proband and her daughter, son, and mother, suggesting autosomal dominant inheritance. The son and daughter also showed atrial septal defects...
August 20, 2016: Auris, Nasus, Larynx
Alice C Coombs, Philip A Bird
OBJECTIVE: To describe the intraoperative findings and outcomes of stapedectomy surgery in Teunissen-Cremers syndrome. PATIENTS: A family of three patients with bilateral conductive hearing loss because of Teunissen-Cremers syndrome. INTERVENTION: Six exploratory tympanotomies and stapedectomies, including one revision operation. MAIN OUTCOME MEASURES: Intraoperative findings and postoperative hearing results. RESULTS: There was an increased distance between the incus and the vestibule, a thicker long process of the incus, and slight variation in the relative position of the ossicles in all patients...
October 2016: Otology & Neurotology
Vivian F Zhu, Yann-Fuu Kou, Kenneth H Lee, Joe Walter Kutz, Brandon Isaacson
OBJECTIVES: 1) To describe the technique for transcanal endoscopic management of congenital ossicular chain fixation. 2) To highlight the utility and outcomes of the endoscopic approach for management of congenital ossicular fixation. STUDY DESIGN: Retrospective patient series. SETTING: Academic tertiary pediatric hospital. PATIENTS: Pediatric patients (age 6-12) undergoing transcanal endoscopic management of congenital ossicular fixation from May 2014 to December 2014...
September 2016: Otology & Neurotology
Maimi Ozeki-Satoh, Aoi Ishikawa, Shigehito Yamada, Chigako Uwabe, Tetsuya Takakuwa
We describe the three-dimensional morphogenesis of the middle ear ossicles (MEOs) according to Carnegie stage (CS) in human embryos. Seventeen samples including 33 MEOs from CS18 to 23 were selected from the Kyoto Collection. The primordia of the MEOs and related structures were histologically observed and three-dimensionally reconstructed from digital images. The timing of chondrogenesis was variable among structures. The stapes was recognizable as a vague condensation of the mesenchymal cells in all samples from CS18, whereas the malleus and incus were recognizable at CS19...
October 2016: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
Charlotte M Burford, Matthew J Mason
It is widely accepted by developmental biologists that the malleus and incus of the mammalian middle ear are first pharyngeal arch derivatives, a contention based originally on classical embryology that has now been backed up by molecular evidence from rodent models. However, it has been claimed in several studies of human ossicular development that the manubrium of the malleus and long process of the incus are actually derived from the second arch. This 'dual-arch' interpretation is commonly presented in otolaryngology textbooks, and it has been used by clinicians to explain the aetiology of certain congenital abnormalities of the human middle ear...
July 26, 2016: Journal of Anatomy
Ricardo Ferreira Bento, Eloisa Maria Mello Santiago Gebrim, Ana Tereza de Matos Magalhães, Larissa Vilela Pereira, Anna Carolina de Oliveira Fonseca
INTRODUCTION: Hearing preservation has not yet been reported in patients undergoing resection of intracochlear schwannomas. This study describes a minimally invasive procedure for intracochlear schwannoma resection with simultaneous cochlear implantation that resulted in good hearing. OBJECTIVE: This study aims to describe a minimally invasive procedure for intracochlear schwannoma resection with simultaneous cochlear implantation. DATA SYNTHESIS: The technique described in this study was developed for a 55-year-old male with a 20-year history of bilateral progressive hearing loss and tinnitus that had a mass in the left apical turn of the cochlea measuring 0...
July 2016: International Archives of Otorhinolaryngology
Xian-Hao Jia, Na Gao, Xin-da Xu, Yong-Zhen Wu, Hou-Yong Kang, Fang-Lu Chi
CONCLUSIONS: The new floating piezoelectric microphone is feasible for use as an implantable middle ear microphone in a totally implantable cochlear implant. OBJECTIVES: A piezoelectric sensor that is driven by the acoustic vibration of the ossicles is one possible design for a microphone for a totally implantable cochlear implant. Such a new floating piezoelectric microphone has been manufactured in the lab. The purpose of this article was to study the frequency response of the new floating piezoelectric microphone in the intact ossicular chain and to identify whether it is usable and implantable...
July 8, 2016: Acta Oto-laryngologica
Luca Bruschini, Francesca Forli, Andrea De Vito, Stefano Berrettini
Objectives: The direct acoustic cochlear implant (DACI) is among the latest developments in the field of implantable acoustic prostheses. The surgical procedure requires a mastoidectomy and a posterior-inferior tympanotomy, with access to the facial recess at the level of the oval window, in a complex and lengthy surgical approach. Here, we report a new and considerably shorter surgical approach. Methods: The new approach involves positioning of artificial incus above the oval window through the superior-anterior tympanotomy...
June 18, 2016: Clinical and Experimental Otorhinolaryngology
Jing Zhang, Jiabin Tian, Na Ta, Xinsheng Huang, Zhushi Rao
Finite element method was employed in this study to analyze the change in performance of implantable hearing devices due to the consideration of soft tissues' viscoelasticity. An integrated finite element model of human ear including the external ear, middle ear and inner ear was first developed via reverse engineering and analyzed by acoustic-structure-fluid coupling. Viscoelastic properties of soft tissues in the middle ear were taken into consideration in this model. The model-derived dynamic responses including middle ear and cochlea functions showed a better agreement with experimental data at high frequencies above 3000 Hz than the Rayleigh-type damping...
August 2016: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
Johannes Schnabl, Astrid Wolf-Magele, Stefan Marcel Pok, Lena Hirtler, Gertraud Heinz, Georg M Sprinzl
OBJECTIVE: Magnetic resonance imaging (MRI) has become an essential tool of modern medical imaging and disease diagnosis. In November 2014, a new MRI-conditional (up to 1.5 T) generation of an active middle ear implant (AMEI) was released to the market.The aim of the study was to test the MRI compatibility of the new implant system in a clinical-anatomical study. DESIGN: Experimental cadaver head model. SETTING: Temporal bone laboratory...
August 2016: Otology & Neurotology
Doğan Atan, Hüseyin Dere, Ali Rıza Yamur, Kürşat Murat Özcan
OBJECTIVE: The aim of our study was to analyze the hearing results of ossicular chain reconstruction in incus long process defects in pediatric patients. METHODS: This retrospective study included 15 pediatric patients that had incus long process defect due to chronic otitis media or adhesive otitis, and repaired with glass ionomer cement between 2009 and 2015. The audiological tests (air conduction thresholds, bone conduction thresholds, air bone gap) obtained preoperatively and one year after surgery were compared...
June 2016: International Journal of Pediatric Otorhinolaryngology
Richard P Tucker, Cathryn A Peterson, Ismail Hendaoui, Sandrine Bichet, Ruth Chiquet-Ehrismann
The ossicles of the middle ear (the malleus, incus and stapes) transmit forces resulting from vibrations of the tympanic membrane to the cochlea where they are coded as sound. Hearing loss can result from diseases such as rheumatoid arthritis (RA) that affect the joints between the ossicles or degenerative processes like otosclerosis that lead to ankylosis of the footplate of the stapes in the oval window of the cochlea. In this study, immunohistochemistry was used to determine if the extracellular matrix glycoproteins tenascin-C or tenascin-W are expressed in the incudomalleolar and incudostapedial joints of ossicles dissected from human cadavers...
September 2016: Journal of Anatomy
Jin Meng, Shundong Bi, Xiaoting Zheng, Xiaoli Wang
The middle ear bones of Mesozoic mammals are rarely preserved as fossils and the morphology of these ossicles in the earliest mammals remains poorly known. Here, we report the stapes and incus of the euharamiyidan Arboroharamiya from the lower Upper Jurassic (∼160 Ma) of northern China, which represent the earliest known mammalian middle ear ossicles. Both bones are miniscule in relation to those in non-mammalian cynodonts. The skull length/stapedial footplate diameter ratio is estimated as 51.74 and the stapes length as the percentage of the skull length is 4%; both numbers fall into the stapes size ranges of mammals...
May 26, 2016: Journal of Morphology
Dagmar Prochazkova, Zuzana Hruba, Petra Konecna, Jarmila Skotakova, Lenka Fajkusova
BACKGROUND: The Wolfram-like syndrome-WFSL is a rare autosomal dominant disease characterised by the triad: congenital progressive hearing loss, diabetes mellitus and optic atrophy. CASE REPORT: The case of a boy with the juvenile form of diabetes mellitus, which clinically matched the symptoms of the Wolfram syndrome, was studied using molecular-genetic methods. At the age of 3¼ years diabetes mellitus was diagnosed in a boy with severe psychomotor retardation, failure to thrive, a dysmorphic face with Peters anomaly type III (i...
May 23, 2016: Journal of Clinical Research in Pediatric Endocrinology
Fernando de Andrade Quintanilha Ribeiro, Yumi Tamaoki, Gabriel Wynne Cabral
INTRODUCTION: Disjunction of ossicular chain is a common finding in middle ear chronic disease. In addition to ossicular interposition, various materials have been used for reconstruction, such as ceramic prostheses, polyethylene, and titanium. OBJECTIVE: Because of the high cost of the available options, the authors propose to reconstruct the ossicular chain with resin cement, a material typically used in dental reconstruction and fixation. METHODS: Two anatomical parts of the temporal bones were used, creating a disjunction of the ossicular chain between the incus and staples and then reconstructing with resin cement...
April 29, 2016: Brazilian Journal of Otorhinolaryngology
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