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https://www.readbyqxmd.com/read/28079680/middle-ear-sound-transmission-under-normal-damaged-repaired-and-reconstructed-conditions
#1
Wei Dong, Ying Tian, Xin Gao, Timothy T K Jung
HYPOTHESIS: We hypothesize that current clinical treatment strategies for the disarticulated or eroded incus have the effect of combining the incus and stapes of the human middle ear (ME) into one rigid structure, which, while capable of adequately transmitting lower-frequency sounds, fails for higher frequencies. BACKGROUND: ME damage causes conductive hearing loss (CHL) and while great progress has been made in repairing or reconstructing damaged MEs, the outcomes are often far from ideal...
January 10, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28068651/comparison-of-alternative-coupling-methods-of-the-vibrant-soundbridge-floating-mass-transducer
#2
Susan Busch, Thomas Lenarz, Hannes Maier
The active middle ear implant Vibrant Soundbridge© provides a variety of coupling modalities of the floating mass transducer (FMT) to various structures of the ossicular chain and the round window. A retrospective analysis was performed on 125 subjects (n = 137 ears) (1) to compare the efficacy of the different FMT coupling modalities with increasing degree of hearing loss, (2) to compare the performance in speech outcome and the effective gain between the coupling types, and (3) to evaluate the risk of additional hearing loss of each coupling procedure...
January 10, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28031153/surgical-management-and-hearing-outcome-of-traumatic-ossicular-injuries
#3
Stefan Delrue, Nicolas Verhaert, Joost van Dinther, Andrzej Zarowski, Thomas Somers, Christian Desloovere, Erwin Offeciers
OBJECTIVE: The purpose of this study was to investigate etiological, clinical, and pathological characteristics of traumatic injuries of the middle ear ossicular chain and to evaluate hearing outcome after surgery. MATERIAL AND METHODS: Thirty consecutive patients (31 ears) with traumatic ossicular injuries operated on between 2004 and 2015 in two tertiary referral otologic centers were retrospectively analyzed. Traumatic events, clinical features, ossicular lesions, treatment procedures, and audiometric results were evaluated...
December 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27959908/ectopic-mineralization-and-conductive-hearing-loss-in-enpp1asj-mutant-mice-a-new-model-for-otitis-media-and-tympanosclerosis
#4
Cong Tian, Belinda S Harris, Kenneth R Johnson
Otitis media (OM), inflammation of the middle ear, is a common cause of hearing loss in children and in patients with many different syndromic diseases. Studies of the human population and mouse models have revealed that OM is a multifactorial disease with many environmental and genetic contributing factors. Here, we report on otitis media-related hearing loss in asj (ages with stiffened joints) mutant mice, which bear a point mutation in the Enpp1 gene. Auditory-evoked brainstem response (ABR) measurements revealed that around 90% of the mutant mice (Enpp1asj/asj) tested had moderate to severe hearing impairment in at least one ear...
2016: PloS One
https://www.readbyqxmd.com/read/27926945/ear-structures-of-the-naked-mole-rat-heterocephalus-glaber-and-its-relatives-rodentia-bathyergidae
#5
Matthew J Mason, Hannah L Cornwall, Ewan St J Smith
Although increasingly popular as a laboratory species, very little is known about the peripheral auditory system of the naked mole-rat, Heterocephalus glaber. In this study, middle and inner ears of naked mole-rats of a range of ages were examined using micro-computed tomography and dissection. The ears of five other bathyergid species (Bathyergus suillus, Cryptomys hottentotus, Fukomys micklemi, Georychus capensis and Heliophobius argenteocinereus) were examined for comparative purposes. The middle ears of bathyergids show features commonly found in other members of the Ctenohystrica rodent clade, including a fused malleus and incus, a synovial stapedio-vestibular articulation and the loss of the stapedius muscle...
2016: PloS One
https://www.readbyqxmd.com/read/27895001/surgical-management-and-hearing-outcome-of-traumatic-ossicular-injuries
#6
Stefan Delrue, Nicolas Verhaert, Joost van Dinther, Andrzej Zarowski, Thomas Somers, Christian Desloovere, Erwin Offeciers
OBJECTIVE: The purpose of this study was to investigate etiological, clinical, and pathological characteristics of traumatic injuries of the middle ear ossicular chain and to evaluate hearing outcome after surgery. MATERIAL AND METHODS: Thirty consecutive patients (31 ears) with traumatic ossicular injuries operated on between 2004 and 2015 in two tertiary referral otologic centers were retrospectively analyzed. Traumatic events, clinical features, ossicular lesions, treatment procedures, and audiometric results were evaluated...
November 28, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27855986/human-cochlear-hydrodynamics-a-high-resolution-%C3%AE-ct-based-finite-element-study
#7
Annalisa De Paolis, Hirobumi Watanabe, Jeremy T Nelson, Marom Bikson, Mark Packer, Luis Cardoso
Measurements of perilymph hydrodynamics in the human cochlea are scarce, being mostly limited to the fluid pressure at the basal or apical turn of the scalae vestibuli and tympani. Indeed, measurements of fluid pressure or volumetric flow rate have only been reported in animal models. In this study we imaged the human ear at 6.7 and 3-µm resolution using µCT scanning to produce highly accurate 3D models of the entire ear and particularly the cochlea scalae. We used a contrast agent to better distinguish soft from hard tissues, including the auditory canal, tympanic membrane, malleus, incus, stapes, ligaments, oval and round window, scalae vestibule and tympani...
January 4, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/27837423/the-effects-of-surgery-type-and-different-ossiculoplasty-materials-on-the-hearing-results-in-cholesteatoma-surgery
#8
Sultan Şevik Eliçora, Duygu Erdem, Aykut Erdem Dinç, Murat Damar, Sultan Bişkin
To investigate the effects of surgery type [intact canal wall (ICW) or canal wall down (CWD) mastoidectomy] and different ossiculoplasty materials on hearing outcome in single-staged cholesteatoma surgery. A retrospective case-control study. A total of 116 cases (97 adults, 29 children) underwent surgery, including ossiculoplasty, between 2012 and 2015 for cholesteatoma. Patients who had undergone surgery for the first time, and whose grafts were successful, were included in the study. Patients with adhesive otitis media, unsuccessful grafts, revision and recurrent cases, radical mastoidectomy, and craniofacial anomalies were excluded...
November 11, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27833873/pre-operative-indicators-of-ossicular-necrosis-in-tubotympanic-csom
#9
Celina Lovely Jayakumar, Leeberk R Inbaraj, George J O Pinto
Ossicular necrosis and erosion is commonly seen in CSOM with cholesteatoma but can also occur in tubotympanic CSOM. This usually comes as a surprise during surgery. Preoperative knowledge of ossicular necrosis helps the surgeon to be better prepared for the surgery and ossicular construction if required. Hence, this study is intended to identify the pre-operative indicators of ossicular necrosis. This cross sectional study was conducted in Father Muller Medical College in Mangalore. Sixty nine consecutive patients with tubotympanic CSOM underwent a detailed clinical examination with pure tone audiometry and subsequently tympanoplasty with or without cortical mastoidectomy...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27832008/transmastoid-endoscopic-assisted-eustachian-tube-packing-after-translabyrinthine-tumor-resection-a-cadaveric-feasibility-study
#10
Nicholas L Deep, Peter A Weisskopf
HYPOTHESIS: Endoscopically assisted packing of the Eustachian tube (ET) will improve visualization of the protympanic space compared with standard techniques with the microscope. BACKGROUND: Postoperative cerebrospinal fluid (CSF) leakage after translabyrinthine tumor resection remains a problem. Current techniques of packing the ET are limited by inadequate visualization. The objective of this study is to demonstrate the feasibility and usefulness of transmastoid endoscopic-assisted ET packing during translabyrinthine tumor resection...
November 9, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27808006/radiologic-detectability-of-the-cochlear-implant-electrode-fixation-clip-using-cone-beam-computed-tomography
#11
Victor Helmstaedter, Eva Bueltmann, Thomas Lenarz, Magnus Teschner
INTRODUCTION: With the aim of preventing migration of cochlear implantation electrodes in the postoperative course, an electrode fixation clip has been developed. It is characterized by two clips of double U-geometry. The bone fixation clip will be clamped on the bony incus bridge, and the electrode fixation clip is clamped to the electrode lead. Although made of titanium, the detectability in radiologic imaging appears limited. MATERIALS AND METHODS: Six patients, who received a cochlear implant between August 2014 and March 2015, were retrospectively analyzed for the detectability of the Med-El Electrode Fixation Clip in postoperative cone beam CT scans...
November 2016: Cochlear Implants International
https://www.readbyqxmd.com/read/27752754/visualization-of-anatomy-in-normal-and-pathologic-middle-ears-by-cone-beam-ct
#12
Christian Güldner, Isabell Diogo, Eva Bernd, Stephanie Dräger, Magis Mandapathil, Afshin Teymoortash, Hesham Negm, Thomas Wilhelm
Cone beam computed tomography (CBCT, syn. digital volume tomography = DVT) was introduced into ENT imaging more than 10 years ago. The main focus was on imaging of the paranasal sinuses and traumatology of the mid face. In recent years, it has also been used in imaging of chronic ear diseases (especially in visualizing middle and inner ear implants), but an exact description of the advantages and limitations of visualizing precise anatomy in a relevant number of patients is still missing. The data sets of CBCT imaging of the middle and inner ear of 204 patients were analyzed regarding the visualization of 18 different anatomic structures...
October 17, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27727526/our-approach-to-revision-stapes-surgery-and-the-outcomes-from-49-procedures-at-a-uk-tertiary-centre
#13
LETTER
H Kanona, M F Bhutta, J Lavy
No abstract text is available yet for this article.
October 11, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27716599/lateral-attic-wall-reconstruction-with-glass-ionomer-bone-cement-in-the-management-of-primary-acquired-attic-cholesteatoma-in-children-a-preliminary-experience
#14
Ahmed Omran, Fatthi Abdel Baki, Ahmed Amin
OBJECTIVE: To assess the effectiveness of glass ionomer bone cement (GIBC) in lateral attic wall reconstruction after primary acquired attic cholesteatoma surgery. MATERIALS AND METHODS: This prospective study was conducted on twenty children collected from the ENT outpatient clinics of a secondary and tertiary hospital. All patients presented with chronic suppurative otitis media with cholesteatoma of the primary acquired attic type. All patients underwent intact canal wall mastoidectomy (ICWM) with a transcanal atticotomy to address primary cholesteatoma involving the attic and the supratubal recess...
August 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27671643/morphology-and-function-of-neandertal-and-modern-human-ear-ossicles
#15
Alexander Stoessel, Romain David, Philipp Gunz, Tobias Schmidt, Fred Spoor, Jean-Jacques Hublin
The diminutive middle ear ossicles (malleus, incus, stapes) housed in the tympanic cavity of the temporal bone play an important role in audition. The few known ossicles of Neandertals are distinctly different from those of anatomically modern humans (AMHs), despite the close relationship between both human species. Although not mutually exclusive, these differences may affect hearing capacity or could reflect covariation with the surrounding temporal bone. Until now, detailed comparisons were hampered by the small sample of Neandertal ossicles and the unavailability of methods combining analyses of ossicles with surrounding structures...
October 11, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27604838/malformations-of-the-middle-and-inner-ear-on-ct-imaging-in-22q11-deletion-syndrome
#16
Elke Loos, Nicolas Verhaert, Annelore Willaert, Koenraad Devriendt, Ann Swillen, Robert Hermans, Katya Op de Beeck, Greet Hens
The 22q11 deletion syndrome (22q11DS), the most frequent microdeletion syndrome in humans, presents with a large variety of abnormalities. A common abnormality is hearing impairment. The exact pathophysiological explanation of the observed hearing loss remains largely unknown. The aim of this study was to analyze the middle and inner ear malformations as seen on computer tomographic imaging in patients with 22q11DS. We retrospectively reviewed the charts of 11 22q11DS patients who had undergone a CT of the temporal bone in the past...
November 2016: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/27552829/novel-syndrome-with-conductive-hearing-loss-and-congenital-glaucoma-in-three-generations
#17
Kazuhiko Takeuchi, Masako Kitano, Hiroshi Sakaida, Sawako Masuda
The objective of this paper was to describe the clinical and otological findings in multiple members of a family with congenital glaucoma, cardiac anomaly, and conductive hearing loss due to ossicular chain anomalies. We performed a retrospective review of the medical charts and otological materials of multiple members of the same family. Congenital glaucoma and hearing loss were inherited by the proband and her daughter, son, and mother, suggesting autosomal dominant inheritance. The son and daughter also showed atrial septal defects...
August 20, 2016: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/27525709/stapedectomy-in-teunissen-cremers-syndrome-intraoperative-findings-and-hearing-outcomes
#18
Alice C Coombs, Philip A Bird
OBJECTIVE: To describe the intraoperative findings and outcomes of stapedectomy surgery in Teunissen-Cremers syndrome. PATIENTS: A family of three patients with bilateral conductive hearing loss because of Teunissen-Cremers syndrome. INTERVENTION: Six exploratory tympanotomies and stapedectomies, including one revision operation. MAIN OUTCOME MEASURES: Intraoperative findings and postoperative hearing results. RESULTS: There was an increased distance between the incus and the vestibule, a thicker long process of the incus, and slight variation in the relative position of the ossicles in all patients...
October 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27525620/transcanal-endoscopic-ear-surgery-for-the-management-of-congenital-ossicular-fixation
#19
Vivian F Zhu, Yann-Fuu Kou, Kenneth H Lee, Joe Walter Kutz, Brandon Isaacson
OBJECTIVES: 1) To describe the technique for transcanal endoscopic management of congenital ossicular chain fixation. 2) To highlight the utility and outcomes of the endoscopic approach for management of congenital ossicular fixation. STUDY DESIGN: Retrospective patient series. SETTING: Academic tertiary pediatric hospital. PATIENTS: Pediatric patients (age 6-12) undergoing transcanal endoscopic management of congenital ossicular fixation from May 2014 to December 2014...
September 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27500982/morphogenesis-of-the-middle-ear-ossicles-and-spatial-relationships-with-the-external-and-inner-ears-during-the-embryonic-period
#20
Maimi Ozeki-Satoh, Aoi Ishikawa, Shigehito Yamada, Chigako Uwabe, Tetsuya Takakuwa
We describe the three-dimensional morphogenesis of the middle ear ossicles (MEOs) according to Carnegie stage (CS) in human embryos. Seventeen samples including 33 MEOs from CS18 to 23 were selected from the Kyoto Collection. The primordia of the MEOs and related structures were histologically observed and three-dimensionally reconstructed from digital images. The timing of chondrogenesis was variable among structures. The stapes was recognizable as a vague condensation of the mesenchymal cells in all samples from CS18, whereas the malleus and incus were recognizable at CS19...
October 2016: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
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