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Roux en Y Gastric Bypass

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https://www.readbyqxmd.com/read/29770924/roux-en-y-gastric-bypass-surgery-induced-weight-loss-and-metabolic-improvements-are-similar-in-tgr5-deficient-and-wildtype-mice
#1
Zheng Hao, R Leigh Townsend, Michael B Mumphrey, Thomas W Gettys, Sangho Yu, Heike Münzberg, Christopher D Morrison, Hans-Rudolf Berthoud
BACKGROUND AND PURPOSE: Roux-en-Y gastric bypass surgery (RYGB) remains one of the most effective treatments for obesity and type 2 diabetes. Despite this, the mechanisms through which it acts are still not well understood. Bile acid signaling through the transmembrane G-protein-coupled receptor TGR5 has been shown to have significant effects on metabolism and has recently been reported to be necessary for the full effects of vertical sleeve gastrectomy (VSG), a bariatric surgery with similar effects to RYGB...
May 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29770188/retrograde-jejunojejunal-intussusception-in-a-pregnant-female-after-laparoscopic-roux-en-y-gastric-bypass
#2
Khuram Khan, Saqib Saeed, Amrita Persaud, Mohammad Sbeih, Sanjiv Gray, Leaque Ahmed
Adult intussusception is a rare complication after laparoscopic Roux-En-Y gastric bypass (LRYGB) surgery. Incidence of intussusception is on the rise as the demand of bariatric surgeries is increased to treat morbid obesity. Among the bariatric surgeries, LRYGB gastric bypass results in significantly higher weight loss with thinning of the mesentery resulting in increased risk for intussusception. Majority of intussusception cases after gastric bypass have been reported in non-pregnant patients. We report a case of retrograde jejunojejunal intussusception in 6 weeks pregnant female following laparoscopic gastric bypass, which was diagnosed with abdominal magnetic resonance imaging and managed successfully with resection and revision of the anastomosis...
May 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29768729/adaptive-changes-in-pancreas-post-roux-en-y-gastric-bypass-induced-weight-loss
#3
A Lautenbach, M Wernecke, N Riedel, J Veigel, J Yamamura, S Keller, R Jung, P Busch, O Mann, F K Knop, J J Holst, J J Meier, J Aberle
AIMS: Obesity has been shown to trigger adaptive increases in pancreas parenchymal and fat volume. Consecutively, pancreatic steatosis may lead to beta-cell dysfunction. However, it is not known, whether the pancreatic tissue components decrease with weight loss and pancreatic steatosis is reversible following RYGB. Therefore, the objective of the study was to investigate the effects of RYGB-induced weight loss on pancreatic volume and glucose homeostasis. MATERIALS AND METHODS: 11 patients were recruited in the Obesity Centre of the University Medical Centre Hamburg-Eppendorf...
May 16, 2018: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/29766309/perioperative-outcomes-and-anesthetic-considerations-of-robotic-bariatric-surgery-in-a-propensity-matched-cohort-of-super-obese-and-super-super-obese-patients
#4
Katherine D Gray, Alfons Pomp, Gregory Dakin, Sonia Amanat, Zachary A Turnbull, Jon Samuels, Cheguevara Afaneh
BACKGROUND: The use of the robotic platform has not been well established in patients with super obesity (SO; body mass index, BMI ≥ 50) and super-super obesity (SSO, BMI ≥ 60). We aimed to determine safety and feasibility of robotic bariatric surgery in this cohort. METHODS: Review of a prospectively maintained database was performed of consecutive patients undergoing robotic bariatric surgery between 2015 and 2017. Propensity score analysis with 1:2 nearest neighbor matching was performed to control for baseline characteristics and procedure type...
May 15, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29766305/evaluation-of-vte-prophylaxis-and-the-impact-of-alternate-regimens-on-post-operative-bleeding-and-thrombotic-complications-following-bariatric-procedures
#5
Maria S Altieri, Jie Yang, Janos Hajagos, Konstantinos Spaniolas, Jihye Park, Antonios P Gasparis, Andrew T Bates, Salvatore Docimo, Mark Talamini, A Laurie Shroyer, Aurora D Pryor
BACKGROUND: Studies examining utilization and impact of venous thromboembolism (VTE) chemoprophylaxis for patients undergoing bariatric surgery are limited. Determination of the optimal prophylactic regimen to minimize complications is crucial. METHODS: The Cerner Health Facts database from 2003 to 2013 was queried using ICD-9 codes to identify patients undergoing laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (RYGB). VTE chemoprophylaxis regimens were divided into pre-operative alone (PreP), post-operative alone (PostP), both pre-operative and post-operative (PPP), or no prophylaxis (NP)...
May 15, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29764908/management-of-endocrine-disease-which-metabolic-procedure-comparing-outcomes-in-sleeve-gastrectomy-and-roux-en-y-gastric-bypass
#6
Adrian T Billeter, Javier de la Garza Herrera, Katharina M Scheurlen, Felix Nickel, Franck Billmann, Beat Müller-Stich
Obesity and its associated comorbidities have become one of the largest challenges for health care in the near future. Conservative therapy for obesity and related comorbidities have a very high failure rate and poor long-term results. Similarly, the conservative and medical management of the majority of metabolic diseases such as type 2 diabetes mellitus are only able to slow down disease progression but have no causal effect on the disease process. Obesity surgery has evolved as a highly effect therapy for severe obesity achieving long-lasting weight loss...
May 15, 2018: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29761876/differential-gip-glp-1-intestinal-cell-distribution-in-diabetics-yields-distinctive-rearrangements-depending-on-roux-en-y-biliopancreatic-limb-length
#7
António M Palha, Sofia S Pereira, Madalena M Costa, Tiago Morais, André F Maia, Marta Guimarães, Mário Nora, Mariana P Monteiro
As incretins are known to play an important role in type 2 diabetics (T2D) improvement observed after Roux-en-Y gastric bypass (RYGB), our aim was to assess whether increasing the length of RYGB biliopancreatic limb in T2D would modify the incretin staining cell density found after the gastric outlet. Small intestine biopsies (n = 38) were harvested during RYGB at two different distances from the duodenal angle; either 60-90 cm (n = 28), from non-diabetic (n = 18) patients, and T2D (n = 10), or 200 cm (n = 10) from T2D...
May 15, 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29756978/comparative-study-of-the-nutritional-status-of-vitamin-a-in-pregnant-women-and-in-women-who-became-pregnant-or-did-not-after-roux-en-y-gastric-bypass
#8
Sabrina Cruz, Suzana Machado, Suelem Cruz, Sílvia Pereira, Carlos Saboya, Andréa Ramalho
INTRODUCTION: the changes in digestive physiology after Roux-en-Y gastric bypass (RYGB), as well as pregnancy, maximizes the risk of vitamin A deficiency (VAD) and both can result in harm to the mother and child health. OBJECTIVE: to compare the nutritional status of vitamin A among women who became pregnant or did not after RYGB and in pregnant women who did not undergo surgery, and to assess the impact of VAD on the mother and child health. METHODS: this is a cross-sectional study of the analytical type...
January 18, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29755786/laparoscopic-assisted-transgastric-ercp-a-single-institution-experience
#9
Katherine Habenicht Yancey, Lauren Katherine McCormack, Stephen Samuel McNatt, Myron Sheavictor Powell, Adolfo Zachariah Fernandez, Carl Joseph Westcott
Background: Laparoscopic-assisted transgastric endoscopic retrograde cholangiopancreatography (LAERCP) is used for treatment in patients after Roux-en-Y gastric bypass (RYGB), where transoral access to the biliary tree is not possible. We describe our technique and experience with this procedure. Methods: Electronic medical record search was performed from September 2012 to January 2016, identifying patients who underwent LAERCP per operative records. Charts were reviewed for demographic, clinical, and outcomes data...
2018: Journal of Obesity
https://www.readbyqxmd.com/read/29754386/nutritional-deficiencies-in-chinese-patients-undergoing-gastric-bypass-and-sleeve-gastrectomy-prevalence-and-predictors
#10
Bingsheng Guan, Jingge Yang, Yanya Chen, Wah Yang, Cunchuan Wang
BACKGROUND: Nutritional deficiencies have been reported in bariatric surgery patients with inconsistent results. However, scarce data exist for Chinese patients. We aimed to assess nutritional deficiencies in Chinese patients undergoing Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), and to identify predictors of postoperative nutritional status. METHODS: A retrospective review of a prospectively collected database was conducted in the patients undergoing RYGB and SG in our hospital between June 2013 and January 2017...
May 12, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29754264/one-year-impact-of-bariatric-surgery-on-serum-anti-mullerian-hormone-levels-in-severely-obese-women
#11
Clara Vincentelli, Marie Maraninchi, René Valéro, Sophie Béliard, Flavia Maurice, Olivier Emungania, Bruno Berthet, Elise Lombard, Anne Dutour, Bénédicte Gaborit, Blandine Courbiere
INTRODUCTION: Although bariatric surgery seems to increase spontaneous fertility by improving ovulatory function in young women, its impact on ovarian reserve remains largely unknown. OBJECTIVE: To evaluate changes in serum anti-Mullerian hormone (AMH) levels in reproductive-age severely obese women after bariatric surgery (BS). METHODS: AMH levels were measured retrospectively in 39 women (mean age 34.6 ± 1.1 years, range 18-45) that underwent a sleeve gastrectomy or Roux-en-Y gastric bypass (RYGB) at baseline, and 6 and 12 months after BS...
May 12, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29753952/outcomes-of-mini-vs-roux-en-y-gastric-bypass-a-meta-analysis-and-systematic-review
#12
REVIEW
Fu-Gang Wang, Wen-Mao Yan, Ming Yan, Mao-Min Song
BACKGROUND: Mini gastric bypass has been proved to be capable of achieving excellent metabolic results by numerous published studies. Compared to Roux-en-Y gastric bypass, mini gastric bypass is a technically simpler and reversible procedure. However, comparative outcomes of the effectiveness between Mini gastric bypass and Roux-en-Y gastric bypass remain unclear. METHODS: A systematic literature search was performed in Pubmed, Embase, Cochrane library from inception to February 9, 2018...
May 10, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29748735/revisional-gastric-bypass-is-inferior-to-primary-gastric-bypass-in-terms-of-short-and-long-term-outcomes-systematic-review-and-meta-analysis
#13
Michał Pędziwiatr, Piotr Małczak, Mateusz Wierdak, Mateusz Rubinkiewicz, Magdalena Pisarska, Piotr Major, Michał Wysocki, W Konrad Karcz, Andrzej Budzyński
PURPOSE: Although Roux-en-Y gastric bypass (RYGB) is the main primary bariatric procedure, it has also been utilized as revisional bariatric surgery. Our aim is to compare revisionary gastric bypass with primary gastric bypass through systematic review with meta-analysis. METHODS: Available literature was searched for eligible studies up to December 2017. Inclusion criteria were reports on morbidity, %EWL, or diabetes remission. Secondary outcomes involved mortality, anastomotic leakage, operative time, and length of hospital stay...
May 11, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29748126/feeding-the-gut-after-revisional-bariatric-surgery-the-fate-of-126-enteral-access-tubes
#14
Andrew T Strong, Hana Fayazzadeh, Gautam Sharma, Kevin El-Hayek, Matthew Kroh, John Rodriguez
BACKGROUND: Revisional bariatric surgery (RBS) is associated with higher complication rates compared with primary bariatric surgery. Feeding tubes (FTs), including gastrostomy and jejunostomy tubes placed during RBS, may serve as a safety net to provide nutrition when oral intake is contraindicated or limited; however, FTs in this setting have not been well investigated. OBJECTIVES: This study aims to determine complications, use, and duration of FTs placed during RBS...
March 9, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29743040/a-dissonance-based-intervention-for-women-post-roux-en-y-gastric-bypass-surgery-aiming-at-improving-quality-of-life-and-physical-activity-24-months-after-surgery-study-protocol-for-a-randomized-controlled-trial
#15
Fanny Sellberg, Sofie Possmark, Ata Ghaderi, Erik Näslund, Mikaela Willmer, Per Tynelius, Anders Thorell, Magnus Sundbom, Joanna Uddén, Eva Szabo, Daniel Berglind
BACKGROUND: Roux-en-Y gastric bypass (RYGB) surgery is the most common bariatric procedure in Sweden and results in substantial weight loss. Approximately one year post-surgery weight regain for these patient are common, followed by a decrease in health related quality of life (HRQoL) and physical activity (PA). Our aim is to investigate the effects of a dissonance-based intervention on HRQoL, PA and other health-related behaviors in female RYGB patients 24 months after surgery. We are not aware of any previous RCT that has investigated the effects of a similar intervention targeting health behaviors after RYGB...
May 9, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29739280/abdominal-pain-after-roux-en-y-gastric-bypass-for-morbid-obesity
#16
Tom Mala, Ingvild Høgestøl
BACKGROUND AND AIMS: Roux-en-Y gastric bypass is widely used as treatment of morbid obesity. Weight loss, effects on obesity-related co-morbidities and quality of life are well documented post Roux-en-Y gastric bypass. Other outcome measures are less well studied. This review explores aspects of prevalence, diagnostic evaluations, etiology, and treatment of abdominal pain specific to Roux-en-Y gastric bypass. METHODS: The review is based on PubMed searches and clinical experience with Roux-en-Y gastric bypass...
May 1, 2018: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/29739229/efficacy-and-safety-of-transoral-outlet-reduction-via-endoscopic-suturing-in-patients-with-weight-regain-after-a-surgical-roux-en-y-gastric-bypass
#17
Eduardo Espinet Coll, Javier Nebreda Durán, Gontrand López-Nava Breviere, Manoel Galvao Neto, José Antonio Gómez Valero, Silvia Bacchiddu, Carmen Vila Lolo, Patricia Díaz Galán, Inmaculada Bautista-Castaño, Antonio Juan-Creix Comamala
INTRODUCTION: many patients that undergo bariatric surgery (Roux-en-Y gastric bypass [RYGB]) may regain some of their weight lost over time. A transoral outlet reduction (TORe) with endoscopic suture could be a valid alternative in these patients. METHODS: this was a retrospective initial series of 13 consecutive patients with weight regain after RYGB and a dilated gastro-jejunal anastomosis (> 15 mm). TORe was performed using an endoscopic transmural suture device (OverStitch-Apollo®), which was used to reduce the anastomosis aperture and also to treat the gastric pouch...
May 9, 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29735347/systematic-assessment-of-decision-analytic-models-for-the-cost-effectiveness-of-bariatric-surgery-for-morbid-obesity
#18
Adnan Alsumali, Ali Al-Hawag, Mihail Samnaliev, Tewodros Eguale
Bariatric surgery among patients with morbid obesity is very effective for providing long-term weight loss and remission of obesity-related co-morbidities. However, it is very expensive and its cost effectiveness is commonly argued. Long-term cost-effectiveness evaluations of bariatric surgery have often relied on decision models. A systematic review was performed on the methodologic approaches and their quality, evaluated the quality of reporting, and summarized findings and conclusions in published cost-effectiveness models of bariatric surgery for morbid obesity...
March 9, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29735346/severe-anemia-after-roux-en-y-gastric-bypass-a-cause-for-concern
#19
Emily McCracken, G Craig Wood, Wesley Prichard, Bruce Bistrian, Christopher Still, Glenn Gerhard, David Rolston, Peter Benotti
BACKGROUND: The current popularity of metabolic surgery has led to increasing attention to long-term nutritional complications. OBJECTIVE: The purpose of this retrospective study is to accurately define the long-term incidence of clinically significant anemia after Roux-en-Y gastric bypass (RYGB) and to identify factors that contribute to increased risk. METHODS: The study cohort consisted of 2116 patients who underwent RYGB with necessary laboratory information available, and with longitudinal follow-up available (mean 5...
March 28, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29732709/restoration-of-enteroendocrine-and-pancreatic-function-after-internal-hernia-and-short-bowel-syndrome-in-a-young-woman-with-gastric-bypass-a-2-year-follow-up
#20
Märta Borghede, Lars Vinter-Jensen, Henrik H Rasmussen, Simon Veedfald, Jens F Rehfeld, Bolette Hartmann, Jens J Holst, Filip K Knop, David P Sonne
A serious complication to the laparoscopic Roux-en-Y gastric bypass (RYGB) is internal hernia, which can lead to massive bowel necrosis that may result in short bowel syndrome. We determined postprandial enteropancreatic hormonal responses and metabolites in a 22-year-old nondiabetic woman with a history of RYGB experiencing severe internal herniation with widespread bowel necrosis. Extensive resections were performed leaving her with a saliva fistula from the pouch-enteric anastomosis, an intact duodenum, 15 cm of jejunum, 35 cm of ileum, and intact colon...
May 2018: Physiological Reports
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