keyword
https://read.qxmd.com/read/38541053/safety-and-efficacy-of-the-use-of-supraglottic-airway-devices-in-children-and-adolescents-undergoing-adenotonsillectomy-a-systematic-review-and-meta-analysis
#21
REVIEW
Abhijit Nair, Nitinkumar Borkar, Sunil Subhash Murke, Ujjwalraj Dudhedia
(1) Background: Supraglottic airway devices (SAD) have been used in children and adolescents undergoing adenotonsillectomies under general anesthesia. This systematic review and meta-analysis investigate the safety and efficacy of using SADs when compared to an endotracheal tube (ETT). (2) Methods: After registering with PROSPERO, databases like PubMed, Scopus, OviD, CINAHL, and Cochrane Library were searched using relevant keywords from the year 2000. We used RoB-2 for risk-of-bias assessment, GRADE for assessing the quality of evidence, RevMan 5...
March 16, 2024: Journal of Personalized Medicine
https://read.qxmd.com/read/38538515/surgical-management-of-pediatric-obstructive-sleep-apnea-beyond-t-a-tongue-base-and-larynx
#22
REVIEW
Matthew Maksimoski, Carol Li
Pediatric patients with persistent obstructive sleep apnea (OSA) after adenotonsillectomy often have additional sites of upper airway obstruction such as the tongue base or larynx. Sleep endoscopy and cross-sectional, dynamic imaging can be used to direct the surgical management of persistent OSA. The tongue base is one of the most common sites of obstruction in children with persistent OSA, especially for patients with Trisomy 21. Lingual tonsillectomy, tongue suspension, and/or posterior midline glossectomy may be used to address lingual tonsil hypertrophy and tongue base obstruction...
March 26, 2024: Otolaryngologic Clinics of North America
https://read.qxmd.com/read/38538338/genetic-and-functional-analyses-of-patients-with-marked-hypo-high-density-lipoprotein-cholesterolemia
#23
JOURNAL ARTICLE
Yasuhisa Furuta, Yoshinori Osaki, Yoshimi Nakagawa, Song-Iee Han, Masaya Araki, Akito Shikama, Nami Ohuchi, Daichi Yamazaki, Erika Matsuda, Seitaro Nohara, Yuhei Mizunoe, Kenta Kainoh, Yasuhito Suehara, Hiroshi Ohno, Yoshinori Takeuchi, Takafumi Miyamoto, Yuki Murayama, Yoko Sugano, Hitoshi Iwasaki, Ken-Ichi Hirano, Masahiro Koseki, Shogo Nakano, Hiroaki Tokiwa, Motohiro Sekiya, Naoya Yahagi, Takashi Matsuzaka, Kiyotaka Nakamagoe, Yasushi Tomidokoro, Jun Mitsui, Shoji Tsuji, Hiroaki Suzuki, Hitoshi Shimano
AIM: This study aimed to analyze two cases of marked hypo-high-density lipoprotein (HDL) cholesterolemia to identify mutations in ATP-binding cassette transporter A1 (ABCA1) and elucidate the molecular mechanism by which these novel pathological mutations contribute to hypo-HDL cholesterolemia in Tangier disease. METHODS: Wild type and mutant expression plasmids containing a FLAG tag inserted at the C-terminus of the human ABCA1 gene were generated and transfected into HEK293T cells...
March 28, 2024: Journal of Atherosclerosis and Thrombosis
https://read.qxmd.com/read/38531270/risk-of-post-tonsillectomy-hemorrhage-among-covid-19-positive-pediatric-patients
#24
JOURNAL ARTICLE
Ann M Martin, Zachary T Elliott, James A Leonard, Jessica H Maxwell, Kelly Scriven, Earl Harley
OBJECTIVE: COVID-19 infection has been demonstrated to increase risk for post-operative bleeding. This study investigated the impact of COVID-19 infection on post-tonsillectomy hemorrhage in pediatric patients, a potentially devastating complication. STUDY DESIGN: Retrospective cohort study. METHODS: The TriNetX database was queried for pediatric patients who underwent tonsillectomy and evaluated for outcomes of primary and secondary post-tonsillectomy hemorrhage...
February 8, 2024: International Journal of Pediatric Otorhinolaryngology
https://read.qxmd.com/read/38530460/the-quality-and-readability-of-patient-information-provided-by-chatgpt-can-ai-reliably-explain-common-ent-operations
#25
JOURNAL ARTICLE
Michel Abou-Abdallah, Talib Dar, Yasamin Mahmudzade, Joshua Michaels, Rishi Talwar, Chrysostomos Tornari
PURPOSE: Access to high-quality and comprehensible patient information is crucial. However, information provided by increasingly prevalent Artificial Intelligence tools has not been thoroughly investigated. This study assesses the quality and readability of information from ChatGPT regarding three index ENT operations: tonsillectomy, adenoidectomy, and grommets. METHODS: We asked ChatGPT standard and simplified questions. Readability was calculated using Flesch-Kincaid Reading Ease Score (FRES), Flesch-Kincaid Grade Level (FKGL), Gunning Fog Index (GFI) and Simple Measure of Gobbledygook (SMOG) scores...
March 26, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38525115/pain-control-is-comparable-between-opioid-versus-non-opioid-management-after-otolaryngology-procedures
#26
JOURNAL ARTICLE
Ashwini Sarathy, Clemens An, Ty Bever, Peter Callas, Mayo H Fujii, Mirabelle Sajisevi
OBJECTIVE: The current study aims to measure patient-reported satisfaction with pain control using opioid and non-opioid medications after undergoing the following otolaryngology procedures: parathyroidectomy, thyroid lobectomy, total thyroidectomy, and bilateral tonsillectomy. MATERIALS AND METHODS: A prospective cohort study was performed at an academic medical center that included a telephone questionnaire and chart review. Opioid prescriptions, usage, and patient-reported pain outcomes were recorded...
April 2024: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/38523050/surgical-management-of-pediatric-obstructive-sleep-apnea-beyond-tonsillectomy-adenoidectomy-tongue-base-and-larynx
#27
REVIEW
Matthew Maksimoski, Carol Li
Pediatric patients with persistent obstructive sleep apnea (OSA) after adenotonsillectomy often have additional sites of upper airway obstruction such as the tongue base or larynx. Sleep endoscopy and cross-sectional, dynamic imaging can be used to direct surgical management of persistent OSA. The tongue base is one of the most common sites of obstruction in children with persistent OSA, especially for patients with Trisomy 21. Lingual tonsillectomy, tongue suspension, and/or posterior midline glossectomy may be used to address lingual tonsil hypertrophy and tongue base obstruction...
March 23, 2024: Otolaryngologic Clinics of North America
https://read.qxmd.com/read/38517763/care-of-the-pediatric-patient-for-ambulatory-tonsillectomy-with-or-without-adenoidectomy-the-society-for-ambulatory-anesthesia-position-statement
#28
JOURNAL ARTICLE
Marjorie P Brennan, Audra M Webber, Chhaya V Patel, Wanda A Chin, Steven F Butz, Niraja Rajan
The landscape of ambulatory surgery is changing, and tonsillectomy with or without adenoidectomy is one of the most common pediatric surgical procedures performed nationally. The number of children undergoing tonsillectomy on an ambulatory basis continues to increase. The 2 most common indications for tonsillectomy are recurrent throat infections and obstructive sleep-disordered breathing. The most frequent early complications after tonsillectomy are hemorrhage and ventilatory compromise. In areas lacking a dedicated children's hospital, these cases are managed by a nonpediatric specialized anesthesiologist and general otolaryngology surgeon...
March 22, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38517544/occurrence-of-mucosa-affecting-diseases-of-the-upper-airways-in-middle-ear-cholesteatoma-patients-a-nationwide-case-control-study
#29
JOURNAL ARTICLE
Agnes Modée Borgström, Hanna Mogensen, Cecilia Engmér Berglin, Johan Knutsson, Åsa Bonnard
PURPOSE: Exploring a possible link between upper airway inflammation and the development of cholesteatoma by studying the association between mucosa-affecting diseases of the upper airways and cholesteatoma surgery. METHODS: This is a nationwide case-control study of 10,618 patients who underwent surgery for cholesteatoma in Sweden between 1987 and 2018. The cases were identified in the National Patient Register and 21,235 controls matched by age, sex and place of residency were included from national population registers...
March 22, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38509834/the-effect-of-surgical-therapy-for-obstructive-sleep-apnea-on-blood-pressure-and-peripheral-arterial-tonometry
#30
JOURNAL ARTICLE
Akshay Tangutur, Yi Cai, Everett G Seay, Erica R Thaler, Brendan T Keenan, Raj C Dedhia
OBJECTIVE: To determine the effect of upper airway surgery on cardiovascular function in patients with obstructive sleep apnea (OSA). STUDY DESIGN: A prospective, self-controlled study from 2018 to 2023. SETTING: Two academic medical centers. METHODS: Seventy-four patients underwent surgery for OSA, including: tonsillectomy, adenoidectomy, epiglottidectomy, modified uvulopalatopharyngoplasty, maxillary expansion, and maxillomandibular advancement...
March 21, 2024: Otolaryngology—Head and Neck Surgery
https://read.qxmd.com/read/38509476/correction-pathologic-tonsillar-findings-similar-to-iga-nephropathy-and-the-role-of-tonsillectomy-in-a-patient-with-nephrotic-syndrome
#31
Takuji Enya, Tomoki Miyazawa, Kohei Miyazaki, Rina Oshima, Yuichi Morimoto, Mitsuru Okada, Tsukasa Takemura, Keisuke Sugimoto
No abstract text is available yet for this article.
March 20, 2024: BMC Nephrology
https://read.qxmd.com/read/38476564/tonsillar-kaposi-s-sarcoma-in-hiv-positive-patient-with-syphilis-infection
#32
Francesco Lorusso, Salvatore Alberto Di Vincenzo, Valerio Campofiorito, Federico Sireci, Angelo Immordino, Francesco Dispenza
INTRODUCTION: Since the introduction of Highly Active Anti-Retroviral Therapy (HAART), there has been a significant increase in the survival of HIV-infected patients. Consequently, there has been increased attention on the potential neoplastic pathologies, such as Kaposi's sarcoma, associated with AIDS in these individuals. CASE REPORT: In this case report we present, for the first time, a patient affected by Kaposi's sarcoma of the palatine tonsil with a concomitant syphilis infection...
March 2024: Iranian Journal of Otorhinolaryngology
https://read.qxmd.com/read/38466063/clinical-application-of-tonsillectomy-with-preservation-of-capsule-and-support-tissue
#33
JOURNAL ARTICLE
Zhiping Pang, Qingyong Chen, Dongqing Wang, Yangyang Yang, Zhipeng Chen, Qiang Shao, Huaiqing Lv
OBJECTIVE: The clinical effect of tonsillectomy with the preservation of tonsillar capsule and stent tissue and punctuated suture of tonsillar capsule and stent tissue was analyzed retrospectively. METHODS: From January 2013 to January 2022, a total of 960 patients underwent tonsillectomy, consisting of 530 males and 430 females with ages ranging from 4 to 60 years (median age: 11 years). The capsule and scaffold tissues were preserved in all patients during the operation, and the surrounding mucosa, capsule, and scaffold tissues were sutured without tension...
March 8, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38466029/metabolomic-profiling-of-pediatric-post-tonsillectomy-pain-a%C3%A2-proof-of-concept-study
#34
JOURNAL ARTICLE
Christian Mpody, Ambrish B Patel, William E Smoyer, Joseph D Tobias, Olubukola O Nafiu
INTRODUCTION: Tonsillectomies are among the most common surgical procedures in children, with over 500 000 cases annually in the United States. Despite universal administration of intraoperative opioid analgesia, three out of five children undergoing tonsillectomy report moderate-to-severe pain upon recovering from anesthesia. The underlying molecular mechanisms of post-tonsillectomy pain are not well understood, limiting the development of targeted treatment strategies. Our study aimed to identify candidate serum metabolites associated with varying severity of post-tonsillectomy pain...
March 11, 2024: Paediatric Anaesthesia
https://read.qxmd.com/read/38465092/subcutaneous-emphysema-following-tonsillectomy-a-rare-complication-of-a-common-surgery
#35
Abdulrahman F Alzamil, Fahad K Bedawi, Danya A AlAseeri, Ebrahim Almulla, Hesham Y Alrayyes, Andrew Riskalla
Post-tonsillectomy emphysema is an infrequent yet critical complication that follows tonsillectomy - a prevalent surgical procedure for treating conditions like recurrent tonsillitis and obstructive sleep apnea. While tonsillectomy is generally safe, it is not without risks, including the rare occurrence of postoperative emphysema, where air accumulates abnormally in the neck and head's soft tissues, potentially leading to severe respiratory distress. We present a case of a middle-aged female who underwent tonsillectomy and subsequently developed symptoms indicative of post-tonsillectomy emphysema...
February 2024: Curēus
https://read.qxmd.com/read/38459431/changes-in-the-nasopharyngeal-and-oropharyngeal-microbiota-in-pediatric-obstructive-sleep-apnea-before-and-after-surgery-a-prospective-study
#36
JOURNAL ARTICLE
Lucheng Fang, Aikebaier Tuohuti, Wanyue Cai, Xiong Chen
OBJECTIVE: To explore the changes and potential mechanisms of microbiome in different parts of the upper airway in the development of pediatric OSA and observe the impact of surgical intervention on oral microbiome for pediatric OSA. METHODS: Before adeno-tonsillectomy, we collected throat swab samples from different parts of the oropharynx and nasopharynx of 30 OSA patients and 10 non-OSA patients and collected throat swab samples from the oropharynx of the above patients one month after the adeno-tonsillectomy...
March 8, 2024: BMC Microbiology
https://read.qxmd.com/read/38455750/narrative-review-in-learning-curve-and-pediatric-robotic-training-program
#37
REVIEW
Giuseppe Autorino, Mario Mendoza-Sagaon, Maria Grazia Scuderi
BACKGROUND AND OBJECTIVE: Studying learning curve (LC) for robotic procedures and developing an adequate training program are two fundamental steps to standardize robotic procedures. With this aim, we analyzed the literature to study the LCs of different robotic procedures and the availability of standardized training problems. METHODS: The PubMed database was searched in the period from January 1995 to September 2022. Articles presenting LC and potential training programs in the pediatric population were chosen...
February 29, 2024: Translational Pediatrics
https://read.qxmd.com/read/38452852/paired-qualitative-and-quantitative-analysis-of-bacterial-microcolonies-in-the-tonsils-of-patients-with-tonsillar-hyperplasia
#38
JOURNAL ARTICLE
Jackson Teh, Kristi Biswas, Sharon Waldvogel-Thurlow, David Broderick, Sita Tarini Clark, James Johnston, Brett Wagner Mackenzie, Richard Douglas
The discovery of bacterial microcolonies in tonsillar tissue of patients with tonsillar hyperplasia has raised the question of their role in provoking the local immune response. Tonsils collected from patients undergoing tonsillectomy were stained for three clinically relevant bacterial taxa and lymphocytes. The bacterial composition and abundance of microcolonies was investigated using a combination of laser-microdissection, amplicon sequencing and Droplet Digital PCR polymerase chain reaction. Microcolonies were detected in most samples (32/35) with a high prevalence of Haemophilus influenzae (78% of samples)...
March 5, 2024: Microbes and Infection
https://read.qxmd.com/read/38451952/pain-management-after-tonsil-surgery-in-children-and-adults-a-national-survey-related-to-pain-outcome-measures-from-the-swedish-quality-register-for-tonsil-surgery
#39
JOURNAL ARTICLE
Maria Roskvist, Fredrik Alm, Pia Nerfeldt, Elisabeth Ericsson
OBJECTIVE: The primary aim of this study was to describe the current practice regarding pain management in relation to tonsil surgery among Ear Nose and Throat (ENT) clinics in Sweden. The secondary aim was to determine the impact of the provider's regime of rescue analgesics on the pain related Patient Reported Outcome Measures (pain-PROMs) from the Swedish Quality Register for Tonsil Surgery (SQTS). MATERIALS & METHODS: A descriptive cross-sectional study originating from a validated web-based questionnaire...
2024: PloS One
https://read.qxmd.com/read/38447265/the-utility-and-accuracy-of-chatgpt-in-providing-post-operative-instructions-following-tonsillectomy-a-pilot-study
#40
JOURNAL ARTICLE
Sarit Dhar, Dhruv Kothari, Missael Vasquez, Travis Clarke, Andrew Maroda, Wade G McClain, Anthony Sheyn, Robert M Tuliszewski, Dennis M Tang, Sanjeet V Rangarajan
OBJECTIVE: To investigate the utility of answers generated by ChatGPT, a large language model, to common questions parents have for their children following tonsillectomy. METHODS: Twenty Otolaryngology residents anonymously submitted common questions asked by parents of pediatric patients following tonsillectomy. After identifying the 16 most common questions via consensus-based approach, we asked ChatGPT to generate responses to these queries. Satisfaction with the AI-generated answers was rated from 1 (Worst) to 5 (Best) by an expert panel of 3 pediatric Otolaryngologists...
April 2024: International Journal of Pediatric Otorhinolaryngology
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