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https://www.readbyqxmd.com/read/28335320/cellular-interactions-and-formation-of-an-epithelial-nanocoating-like-barrier-with-mesoporous-silica-nanoparticles
#1
Xuan Li, Ka Yan Pang, Tsz Wing Ng, Ping Chung Leung, Cheng Fei Zhang, Ken Cham-Fai Leung, Lijian Jin
Oral mucosa as the front-line barrier in the mouth is constantly exposed to a complex microenvironment with multitudinous microbes. In this study, the interactions of mesoporous silica nanoparticles (MSNs) with primary human gingival epithelial cells were analyzed for up to 72 h, and their diffusion capacity in the reconstructed human gingival epithelia (RHGE) and porcine ear skin models was further assessed at 24 h. It was found that the synthesized fluorescent mesoporous silica nanoparticles (RITC-NPs) with low cytotoxicity could be uptaken, degraded, and/or excreted by the human gingival epithelial cells...
October 27, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28333776/transcanal-endoscopic-ear-surgery-for-middle-ear-cholesteatoma
#2
Eran Glikson, Ruth Yousovich, Jobran Mansour, Michael Wolf, Lela Migirov, Yisgav Shapira
OBJECTIVE: To evaluate the clinical parameters, outcomes, and complications of transcanal endoscopic ear surgeries for middle ear cholesteatoma. STUDY DESIGN: Retrospective study. SETTING: Tertiary university-affiliated medical center. PATIENTS: Adult patients (age >18) who underwent transcanal endoscopic ear surgeries for cholesteatoma, between March 2009 and March 2015. INTERVENTION: Transcanal endoscopic surgery was indicated when the cholesteatoma did not extend posterior to the anterior limb of the lateral semicircular canal...
March 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28330628/analysis-of-the-dura-involvement-in-cholesteatoma-surgery
#3
David Schwarz, Antoniu-Oreste Gostian, Sami Shabli, Philipp Wolber, Karl Bernd Hüttenbrink, Andreas Anagiotos
OBJECTIVE: The involvement of the dura is a rare yet potentially life-threatening complication during cholesteatoma surgery. Thus, the knowledge about treatment and consequences of this issue is of great importance to every ear surgeon. METHODS: This retrospective study analyzed the dura involvement with regard to the type of defect, reconstruction method used, and the post-operative complications of 1291 pediatric and adult cholesteatoma surgeries performed at an academic tertiary care center over a twelve-year period...
March 19, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28326677/implantation-and-positioning-of-a-transcutaneous-magnetic-bone-conduction-hearing-system-for-children-with-microtia-in-preparation-for-auricular-reconstruction
#4
Shradha Sharma, Neil Bulstrode, Andrew Marshall
Microtia is a complex congential issue, which can have a functional and psychosocial effect on patients(1) . It can occur spontaneously or as part of a syndrome. Microtia is a condition in which otolaryngologists and plastic surgeons work closely together in order to reconstruct the ear aesthetically whilst facilitating effective aiding. This article is protected by copyright. All rights reserved.
March 22, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28326539/isotopic-niche-partitioning-between-two-apex-predators-over-time
#5
M Drago, L Cardona, V Franco-Trecu, E A Crespo, D Vales, F Borella, L Zenteno, E M Gonzáles, P Inchausti
1.Stable isotope analyses have become an important tool in reconstructing diets, analyzing resource use patterns, elucidating trophic relations among predators and understanding the structure of food webs. 2.Here, we use stable carbon and nitrogen isotope ratios in bone collagen to reconstruct and compare the isotopic niches of adult South American fur seals (Arctocephalus australis; n = 86) and sea lions (Otaria flavescens; n = 49) -two otariid species with marked morphological differences- in the Río de la Plata estuary (Argentina - Uruguay) and the adjacent Atlantic Ocean during the second half of the 20(th) century and the beginning of the 21(st) century...
March 22, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28322453/radio-anatomical-analysis-of-the-pericranial-flap-money-box-approach-for-ventral-skull-base-reconstruction
#6
Alfonso Santamaría, Cristóbal Langdon, Mauricio López-Chacon, Arturo Cordero, Joaquim Enseñat, Ricardo Carrau, Manuel Bernal-Sprekelsen, Isam Alobid
OBJECTIVES/HYPOTHESIS: To evaluate the versatility of the pericranial flap (PCF) to reconstruct the ventral skull base, using the frontal sinus as a gate for its passage into the sinonasal corridor "money box approach." STUDY DESIGN: Anatomic-radiological study and case series. METHODS: Various approaches and their respective defects (cribriform, transtuberculum, clival, and craniovertebral junction) were completed in 10 injected specimens...
March 21, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28300924/staged-retroauricular-flap-for-helical-reconstruction-after-mohs-micrographic-surgery
#7
Felipe Bochnia Cerci
Staged retroauricular flap is a great option for full-thickness defects along the helical rim and antihelix. Donor site consists of the posterior ear, postauricular sulcus and mastoid area. The advantages of this flap include hidden donor scar, donor tissue similarity and rich vascularity. We present a case of collision tumor on the left helix treated with Mohs micrographic surgery and the resulting full-thickness defect repaired with a staged retroauricular flap. This flap is an effective technique for full-thickness helical defect repair with relatively little operative morbidity...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28293515/anatomical-and-clinical-study-of-the-posterior-auricular-artery-angiosome-in-search-of-a-rescue-tool-for-ear-reconstruction
#8
Oswaldo J Gómez Díaz, Mario D Cruz Sánchez
BACKGROUND: The retroauricular tissues have been used for a long time for ear reconstruction, but the anatomical bases of flaps of this region are not completely clear. The aim of this study was to estimate blood supply area and location of this on the skin and fascia retroauricular dependent of posterior auricular artery (PAA) to establish safe margins to design flaps for auricular reconstruction. METHODS: Dissection under magnification (×3.5) of the PAA through a cervical approach; injection of methylmethacrylate in the PAA as a staining technique; retroauricular approach to identify the territory of irrigation of PAA in the retroauricular skin and fascia; measuring and location of the stained area; and report of 2 cases of ear reconstruction with fasciocutaneous and fascia flaps based on PAA, designed according to the anatomical study...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28293505/accurate-measurements-of-the-skin-surface-area-of-the-healthy-auricle-and-skin-deficiency-in-microtia-patients
#9
Iris A Otto, Rob F M van Doremalen, Ferry P W Melchels, Michail N Kolodzynski, Behdad Pouran, Jos Malda, Moshe Kon, Corstiaan C Breugem
BACKGROUND: The limited cranial skin covering auricular implants is an important yet underrated factor in auricular reconstruction for both reconstruction surgery and tissue engineering strategies. We report exact measurements on skin deficiency in microtia patients and propose an accessible preoperative method for these measurements. METHODS: Plaster ear models (n = 11; male:female = 2:1) of lobular-type microtia patients admitted to the University Medical Center Utrecht in The Netherlands were scanned using a micro-computed tomographic scanner or a cone-beam computed tomographic scanner...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28279397/-reconstruction-of-the-ear-in-the-burns-patient
#10
Jorge Raúl Carrillo-Córdova, Yusef Jiménez Murat, Armando Apellaniz-Campo, Hazel Bracho-Olvera, Raúl Carrillo Esper
Face burns are a singular pathology with great functional and psychological impact in the patients suffering them. The ears play a fundamental role in personal interactions and damage to this organ results in physical and emotional distress. The reconstructive treatment of the burned ear is a challenge. Multiple procedures have been described to achieve success in the reconstruction of the burned ear; immediate reconstruction with autologous rib cartilage, secondary reconstruction, alloplastic material reconstruction, tissue expansion, skin grafts and also microvascular flaps are some of the most common procedures used in this patients...
March 6, 2017: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28277483/endoscopy-assisted-ear-surgery-for-treatment-of-chronic-otitis-media-with-cholesteatoma-adhesion-or-retraction-pockets
#11
Cagatay Han Ulku
The objective of this study was to analyze the results of endoscopy-assisted ear surgery for the treatment of chronic otitis media with cholesteatoma, adhesion, or retraction pockets.Fifty-one patients who underwent oto-endoscopy-assisted canal wall up tympanomastoid surgery and/or limited anterior atticotomy with tympanoplasty for chronic otitis media with cholesteatoma, adhesion, or retraction pocket from 2006 to 2013 have been included in this study. Eradication of the disease from the middle ear and mastoid air cells was achieved by combination of the oto-microscobic and oto-endoscopic approaches...
March 8, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28277272/a-case-report-on-a-burned-ear-elastic-memory-of-cartilage-following-temporary-burial-in-a-skin-pocket
#12
D O Visscher, P P M van Zuijlen
Preserving exposed ear cartilage following a facial burn remains a major challenge. Normally, burned ear cartilage cannot be preserved in case of a full thickness burn of the overlying skin, and the cartilage has to be surgically removed. Sometimes, reconstructions can be performed at a later stage. We report a case where burned ear cartilage was directly surgically buried in a retroauricular skin pocket showing remarkable elastic memory: the buried ear cartilage, in this case the antihelix, regenerated over time and regained its original position protruding from the facial area...
October 27, 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28274897/surgical-treatment-of-external-auditory-canal-cholesteatoma-ten-years-of-clinical-experience
#13
Kuen Yao Ho, Tzu Yen Huang, Shih Meng Tsai, Hsun Mo Wang, Chen Yu Chien, Ning Chia Chang
OBJECTIVE: To describe the clinical manifestations of external auditory canal (EAC) cholesteatoma and evaluate the surgical outcomes of reconstruction using an inferior pedicled soft-tissue periosteum flap. MATERIALS AND METHODS: A total of 28 patients were enrolled in this retrospective study conducted at Kaohsiung Medical University Hospital in Taiwan between January 2004 and December 2013. EAC cholesteatoma was classified according to the disease extent. The surgery was performed to reconstruct a smooth contour of EAC...
March 9, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28269610/middle-and-inner-ear-modelling-from-microct-images-to-3d-reconstruction-and-coupling-of-models
#14
N S Tachos, A I Sakellarios, G Rigas, V Isailovic, G Ni, F Bohnke, N Filipovic, T Bibas, D I Fotiadis
We present finite element (FE) modeling approaches of ear mechanics including 3-dimensional (3D) reconstruction of the human middle and inner ear. Specifically, we demonstrate a semi-automatic methodology for the 3D reconstruction of the inner ear structures, a FE harmonic response model of the middle ear to predict the stapes footplate frequency response, a 2D FE slice model of the cochlea for the coupled response at the micromechanical level for either acoustic or electrical excitation and a coupled FE middle ear model with a simplified cochlea box model to simulate the basilar membrane velocity in response to acoustic excitation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227868/middle-and-inner-ear-modelling-from-microct-images-to-3d-reconstruction-and-coupling-of-models
#15
N S Tachos, A I Sakellarios, G Rigas, V Isailovic, G Ni, F Bohnke, N Filipovic, T Bibas, D I Fotiadis, N S Tachos, A I Sakellarios, G Rigas, V Isailovic, G Ni, F Bohnke, N Filipovic, T Bibas, D I Fotiadis, A I Sakellarios, V Isailovic, D I Fotiadis, A Bibas, F Bohnke, G Ni, N Filipovic, G Rigas, N S Tachos
We present finite element (FE) modeling approaches of ear mechanics including 3-dimensional (3D) reconstruction of the human middle and inner ear. Specifically, we demonstrate a semi-automatic methodology for the 3D reconstruction of the inner ear structures, a FE harmonic response model of the middle ear to predict the stapes footplate frequency response, a 2D FE slice model of the cochlea for the coupled response at the micromechanical level for either acoustic or electrical excitation and a coupled FE middle ear model with a simplified cochlea box model to simulate the basilar membrane velocity in response to acoustic excitation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226370/osseous-and-cartilaginous-nasal-reconstruction
#16
Samuel Hahn
The nose is a complex, three-dimensional structure that is supported by a framework of osseous and cartilaginous structures. Disruption of this framework can result in nasal deformity and functional deficits. Nasal reconstruction requires restoration of the osseous and cartilaginous framework. This requires careful preoperative assessment of the nasal defect and understanding the nasal and facial aesthetics that are supported by the osseous and cartilaginous support structures. Structural grafts can be classified as restorative, supportive, or contouring...
February 2017: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/28207625/a-three-dimensional-geometric-morphometric-study-to-quantify-temporal-bone-growth-and-its-consequences-for-the-success-of-implanting-bone-anchored-hearing-devices
#17
Sebastian Schilde, Stefan K Plontke, Torsten Rahne
OBJECTIVE: A computed tomography (CT)-based morphological-investigation to describe temporal bone growth and to devise a predictive test of the likely success of Bonebridge implantation into the growing mastoid region of the temporal bone in young patients. STUDY DESIGN: Retrospective cross-sectional study. SETTING: University Hospital Halle (Saale), Germany. PATIENTS: Two cohorts participated. This first, of patients aged less than 21 years, comprised 42 men, and 33 women patients...
February 15, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28198774/a-new-classification-of-helix-fabrication-methods-with-autogenous-costal-cartilage-in-microtia-reconstruction
#18
Zhicheng Xu, Feng Xu, Ruhong Zhang, Qun Zhang, Datao Li, Yiyuan Li
BACKGROUND: The complex architecture of the auricle poses one of the most demanding challenges for the plastic surgeon to recreate. The fabrication of the prominent helix is crucial to the final contour of the constructed ear. The success of helix carving depends greatly on the complicated characteristics of the cartilage used, which is commonly the eighth costal cartilage. The authors elaborate on the relevant details for helix sculpting based on different qualities of cartilage. METHODS: A series of 415 microtia patients underwent autogenous costal cartilage auricular reconstruction between 2012 and 2015...
February 13, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28196606/imaging-and-cell-count-in-cleared-intact-cochlea-in-the-mongolian-gerbil-using-laser-scanning-confocal-microscopy
#19
M Risoud, J Sircoglou, G Dedieu, M Tardivel, C Vincent, N-X Bonne
OBJECTIVES: To draw up a clearing protocol for Mongolian gerbil cochlea, and to assess the feasibility of quantifying and analyzing 3D cell architecture in the transparent cochleae. MATERIALS AND METHODS: Freshly dissected inner ears were prepared on a 13-day protocol: fixation, microdissection, post-fixation, decalcification, pretreatment (signal enhancement, permeabilization and blocking), fluorescent labeling (indirect immunolabeling and direct labeling), dehydration, clearing in Spalteholz solution (MSBB: methyl salicylate and benzyl benzoate) and mounting...
February 9, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/28194323/usage-of-a-rotational-flap-for-coverage-of-a-large-central-forehead-defect
#20
Ahmed Hassan El-Sabbagh
Background: The forehead is a donor site for facial reconstruction but has no generous donor site for its coverage. All options of the reconstructive ladder can be used. A large rotation flap was used to reconstruct a big central forehead defect following failed previous repair in an elderly diabetic patient after a motor car accident. Case presentation: A 64-year-old diabetic man presented with an extensive central forehead defect after failed previous repair following a motor car accident. Coverage of the defect was performed using a flap based around the ear on one side in a rotation movement...
2017: GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW
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