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https://www.readbyqxmd.com/read/29330780/safety-in-mixed-martial-arts-a-7-year-review-of-cancelled-mma-bouts-in-calgary-alberta-during-the-pre-bout-medical-examination-period
#1
Gwynn Curran-Sills
BACKGROUND: Presently, there is no literature that examines the reasons for the cancellation of amateur or professional mixed martial arts (MMA) bouts. The purpose of this study was to review the circumstances that lead to the cancellation of MMA bouts by Calgary ringside physicians during the pre-bout examination period and to identify any emerging patterns that may guide the regulatoin of this sport. METHODS: The case-series  was constructed from the Calgary Combative Sports Commission pre-bout examination records and the medical records submitted by each athlete from January 2010 to December 2016...
January 12, 2018: Sports Medicine—Open
https://www.readbyqxmd.com/read/29330214/statins-have-a-dose-dependent-effect-on-amputation-and-survival-in-peripheral-artery-disease-patients
#2
Shipra Arya, Anjali Khakharia, Zachary O Binney, Randall R DeMartino, Luke P Brewster, Philip P Goodney, Peter W F Wilson
Background -Statin dose guidelines for Peripheral Artery Disease (PAD) patients are largely based on coronary artery disease and stroke data. The aim of this study is to determine the effect of statin intensity on PAD outcomes of amputation and mortality. Methods -Using an observational cohort study design and a validated algorithm we identified incident PAD patients (2003-2014) in the national Veterans Affairs data. Highest statin intensity exposure [high intensity vs low- moderate intensity vs antiplatelet therapy but no statin use (AP only)] was determined within one year of diagnosis of PAD...
January 12, 2018: Circulation
https://www.readbyqxmd.com/read/29315259/the-evolving-treatment-of-peripheral-arterial-disease-through-guideline-directed-recommendations
#3
REVIEW
Ramez Morcos, Boshra Louka, Andrew Tseng, Sanjay Misra, Robert McBane, Heidi Esser, Fadi Shamoun
Peripheral arterial disease (PAD) refers to partial or complete occlusion of one or more non-coronary arteries that leads to compromised blood flow and ischemia. Numerous processes are involved in arterial stenosis, however, atherosclerosis remains the most common etiology. PAD constitutes a major health economic problem, and it is estimated that over 200 million people around the world suffer from PAD, with at least 20% having some degree of claudication. The purpose of this review is to compare and contrast the guidelines on PAD published in 2005, 2011 and 2016 in terms of new recommendations and level of evidence for practicing clinicians...
January 9, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29274894/the-physical-activity-daily-pad-trial-the-rationale-and-design-of-a-randomized-controlled-trial-evaluating-an-internet-walking-program-to-improve-maximal-walking-distance-among-patients-with-peripheral-arterial-disease
#4
Anjana M Kumar, Angela K Lyden, Noelle E Carlozzi, Ananda Sen, Caroline R Richardson, Elizabeth A Jackson
BACKGROUND: Despite established guidelines for regular walking as a first line therapy for adults with peripheral arterial disease (PAD), most patients do not walk routinely. This paper presents the design specifications for a randomized clinical trial to examine the effectiveness of an internet-based walking program compared to a telephone intervention, or the combination (internet-based with telephone counseling) for promotion of regular walking in patients with PAD. METHODS: Sedentary adults with documented lower extremity PAD are being recruited from the University of Michigan Health System and the surrounding area...
December 21, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29246468/enuresis-management-in-children-retrospective-clinical-audit-of-2861-cases-treated-with-practitioner-assisted-bell-and-pad-alarm
#5
Esther Apos, Sharynn Schuster, John Reece, Shirley Whitaker, Kerry Murphy, John Golder, Beverley Leiper, Linda Sullivan, Susie Gibb
OBJECTIVE: To establish the treatment efficacy of practitioner-assisted bell-and-pad alarm therapy in children with enuresis between the ages of 5 and 16 years by retrospective medical chart review of 2861 children in multiple clinical settings. STUDY DESIGN: This review was conducted across 7 Australian clinical practices. The primary outcome measure was the time taken for children with either primary, secondary, monosymptomatic, or nonmonosymptomatic enuresis to be dry for 14 consecutive nights...
December 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29230514/-guideline-recommendations-and-quality-indicators-for-invasive-treatment-of-peripheral-arterial-disease-in-germany-the-idomeneo-study-for-quality-improvement-and-research-in-vascular-medicine
#6
REVIEW
Christian-Alexander Behrendt, Henrik Rieß, Martin Härter, Levente Kriston, Hannes Federrath, Ursula Marschall, Eike Sebastian Debus
Due to the paucity of independent trials, practical guidelines for the diagnosis and treatment of peripheral arterial disease (PAD) contain several recommendations developed by expert consensus. Furthermore, there is a lack of commonly defined quality indicators and valid data on real world treatment. Therefore, it remains challenging to scrutinize if treatment reality is conforming to guideline recommendations. This article aims to give a short overview on existing guideline recommendations. It further aims to introduce the multistage multimethodological IDOMENEO study, utilizing primary registry data (GermanVasc) and health insurance claims data (BARMER) in PAD treatment...
December 11, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/29197254/utilization-of-lipid-modifying-therapy-and-low-density-lipoprotein-cholesterol-goal-attainment-in-patients-at-high-and-very-high-cardiovascular-risk-real-world-evidence-from-germany
#7
Winfried März, Franz-Werner Dippel, Karlheinz Theobald, Katherine Gorcyca, Şerban R Iorga, David Ansell
BACKGROUND AND AIMS: Elevated low-density lipoprotein cholesterol (LDL-C) is a causal risk factor for cardiovascular (CV) events. European guidelines recommend reducing LDL-C as the primary lipid target to reduce CV risk, using lifestyle modifications and lipid-lowering therapy (LLT). Many European patients do not achieve guideline-recommended LDL-C levels. The present database analysis aimed to assess LLT treatment patterns and LDL-C threshold attainment in Germany in a large, real-world cohort of patients...
November 20, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29145873/group-physiotherapy-compared-to-individual-physiotherapy-to-treat-urinary-incontinence-in-aging-women-study-protocol-for-a-randomized-controlled-trial
#8
Chantale Dumoulin, Mélanie Morin, Marie-Hélène Mayrand, Michel Tousignant, Michal Abrahamowicz
BACKGROUND: Urinary incontinence (UI), one of the most prevalent health concerns confronting women aged over 60 years, affects up to 55% of older community-dwelling women-20-25% with severe symptoms. Clinical practice guidelines recommend individualized pelvic floor muscle training (PFMT) as a first-line treatment for stress or mixed UI in women, although lack of human and financial resources limits delivery of this first-line treatment. Preliminary data suggest that group-based treatments may provide the answer...
November 16, 2017: Trials
https://www.readbyqxmd.com/read/29125051/how-to-become-proficient-in-performance-of-the-resting-ankle-brachial-index-results-of-the-first-randomized-controlled-trial
#9
Céline Donnou, Ségolène Chaudru, Olivier Stivalet, Eunice Paul, Marie Charasson, Jean-Marc Selli, Chadi Mauger, Anthony Chapron, Alexis Le Faucheur, Vincent Jaquinandi, Guillaume Mahé
The resting ankle-brachial index (ABI) is a first-line test to diagnose peripheral artery disease (PAD). No randomized controlled trial (RCT) has yet been conducted to determine the best teaching method to become proficient in the ABI procedure. We conducted a monocentric RCT to determine whether didactic learning alone or didactic learning combined with experiential learning improved proficiency in the ABI procedure. Medical students ( n = 30) received didactic learning, including (i) a presentation of the ABI guidelines and (ii) a video demonstration...
November 1, 2017: Vascular Medicine
https://www.readbyqxmd.com/read/28981207/medication-related-osteonecrosis-of-the-posterior-maxilla-surgical-treatment-using-a-combined-transnasal-endoscopic-and-intraoral-approach-our-experience-with-seven-consecutive-patients
#10
Pasquale Procacci, Massimo Albanese, Lorenzo Trevisiol, Vittorio Favero, Dario Bertossi, Fabio Lonardi, Antonio D'Agostino, Erminia Manfrin, Pier Francesco Nocini
Upper jaw MRONJ if not correctly treated can lead to serious complication. Upper jaw MRONJ is frequently associated with maxillary sinusitis, the disease can spread to other paranasal sinuses. Combined approach is the most reliable procedure to treat odontogenic sinusitis; although MRONJ associated sinusitis is considered odontogenic there is no report in literature describing combined approach to treat MRONJ-induced sinusitis. Buccal fat pad represents the best reconstructive option to close the bony defect...
October 5, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28950823/statins-in-peripheral-arterial-disease
#11
Scott T Chiesa, Nikos Papageorgiou, Marietta Charakida
Peripheral arterial disease (PAD) is a common atherosclerotic condition affecting the lower extremities. PAD patients share similar cardiovascular risk factors to coronary artery disease patients and suffer from increased cardiovascular morbidity and mortality. Statins have been widely used in coronary artery disease patients but have been underused in patients with PAD. In the current review, we present data, which support the beneficial role of statins in both reducing cardiovascular events and improving symptom-related outcomes in PAD patients...
September 26, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28911310/how-to-treat-patients-with-essential-hypertension-and-peripheral-arterial-disease
#12
Salvatore Santo Signorelli
BACKGROUND: Arterial hypertension (AH) and peripheral arterial disease (PAD) frequently coincide. While significant attention is paid to AH, PAD is often underestimated. It is known that both AH and PAD present high cardiovascular risks for ischemic events. To date, the use of the most common anti-hypertensive drugs in PAD patients is still under debate. METHODS: Data from studies of large populations and minor cohorts of patients show AH and PAD together or PAD alone...
June 7, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28895369/the-role-of-intravascular-ultrasound-in-lower-limb-revascularization-in-patients-with-peripheral-arterial-disease
#13
Gregory C Makris, Pavlina Chrysafi, Mark Little, Rafiuddin Patel, Mark Bratby, Andrew Wigham, Susan Anthony, Raman Uberoi
INTRODUCTION: The aim of this review is to explore the safety and effectiveness of intravascular ultrasound (IVUS) during lower limb endovascular interventions in patients with peripheral arterial disease (PAD). METHODS: A systematic review of the PubMed and Scopus databases was performed according to PRISMA guidelines. Clinical studies evaluating IVUS as an adjunct to angiography during revascularization procedures in patients with PAD were included. RESULTS: Thirteen studies were identified, with a total number of 2,258 patients having had IVUS for PAD intervention...
September 11, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/28887241/noninvasive-peripheral-artery-disease-screening-tools-a-deficient-knowledge-among-french-vascular-residents-from-4-medical-schools
#14
Olivier Stivalet, Loukman Omarjee, Segolene Chaudru, Clement Hoffmann, Luc Bressollette, Kevin P Cohoon, Vincent Jaquinandi, Guillaume Mahe
BACKGROUND: Ankle-brachial index (ABI) at rest, postexercise ABI, and toe-brachial index (TBI) are essential diagnostic tools recommended for peripheral artery disease (PAD) diagnosis. Our study investigates the level of knowledge on these 3 tests among vascular medicine residents from 4 French medical schools in France. METHODS: We included 19 vascular medicine residents in a cross-sectional study. During an annual obligatory seminar, all residents accepted to fill 3 questionnaires concerning knowledge about these 3 tests...
September 6, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28834167/feasibility-and-safety-of-focal-irreversible-electroporation-as-salvage-treatment-for-localized-radio-recurrent-prostate-cancer
#15
Matthijs J Scheltema, Willemien van den Bos, Amila R Siriwardana, Anton M F Kalsbeek, James E Thompson, Francis Ting, Maret Böhm, Anne-Maree Haynes, Ron Shnier, Warick Delprado, Phillip D Stricker
OBJECTIVES: To evaluate the feasibility, safety, early quality-of-life (QoL) and oncological outcomes of salvage focal irreversible electroporation (IRE) for radio-recurrent prostate cancer (PCa). PATIENTS AND METHODS: Patients with localized, radio-recurrent PCa without evidence of metastatic or nodal disease were offered focal IRE according to the consensus guidelines. Patients with a minimum follow-up of 6 months were eligible for analysis. Adverse events were monitored using the National Cancer Institute Common Terminology Criteria for Adverse Events (CTCAE version 4...
November 2017: BJU International
https://www.readbyqxmd.com/read/28827131/community-socioeconomic-status-and-public-access-defibrillators-a-multilevel-analysis
#16
Sun Young Lee, Young Kyung Do, Sang Do Shin, Yong Joo Park, Young Sun Ro, Eui Jung Lee, Kyoung Won Lee, Yu Jin Lee
BACKGROUND: Although current guidelines recommend that distribution of public-access defibrillators (PADs) should take into account area-level risk of out-of-hospital cardiac arrest (OHCA), community socioeconomic status (SES) can unduly influence policy implementation in positioning PADs. Using recent, complete data from Seoul Metropolitan City, Korea, this study aims to examine whether community SES is associated with distribution of PADs, in terms of per capita count and risk-grid coverage...
November 2017: Resuscitation
https://www.readbyqxmd.com/read/28822512/implications-of-the-2013-acc-aha-cholesterol-guidelines-on-contemporary-clinical-practice-for-patients-with-atherosclerotic-coronary-and-peripheral-arterial-disease
#17
Prasad Gunasekaran, Vinodh Jeevanantham, Suresh Sharma, Rashmi Thapa, Kamal Gupta
BACKGROUND: Cholesterol management guidelines from the American College of Cardiology/American Heart Association (ACC/AHA-2013) recommend fixed statin dosing (dose depends on age ≤ or >75years) compared to the earlier adult treatment panel III (ATPIII) guidelines which recommended specific low-density lipoprotein-cholesterol (LDL-C) targets. Clinical implications of this recommendation are not known. METHODS: We retrospectively compared cholesterol levels and statin utilization across cohorts with coronary artery disease (CAD) (n=9563), peripheral arterial disease (PAD) (n=596) and CAD+PAD (n=975) by applying both guidelines...
July 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28815100/surveillance-of-peripheral-arterial-disease-cases-using-natural-language-processing-of-clinical-notes
#18
Naveed Afzal, Sunghwan Sohn, Christopher G Scott, Hongfang Liu, Iftikhar J Kullo, Adelaide M Arruda-Olson
Peripheral arterial disease (PAD) is a chronic disease that affects millions of people worldwide and yet remains underdiagnosed and undertreated. Early detection is important, because PAD is strongly associated with an increased risk of mortality and morbidity. In this study, we built a PAD surveillance system using natural language processing (NLP) for early detection of PAD from narrative clinical notes. Our NLP algorithm had excellent positive predictive value (0.93) and identified 41% of PAD cases before the initial ankle-brachial index (ABI) test date while in 12% of cases the NLP algorithm detected PAD on the same date as the ABI (the gold standard for comparison)...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28765738/baseline-characteristics-of-a-retrospective-patient-cohort-in-the-korean-vascular-intervention-society-endovascular-therapy-in-lower-limb-artery-diseases-k-vis-ella-registry
#19
Young-Guk Ko, Chul-Min Ahn, Pil-Ki Min, Jae-Hwan Lee, Chang-Hwan Yoon, Cheol Woong Yu, Seung Whan Lee, Sang-Rok Lee, Seung Hyuk Choi, Yoon Seok Koh, In-Ho Chae, Donghoon Choi
BACKGROUND AND OBJECTIVES: The Korean Vascular Intervention Society Endovascular Therapy in Lower Limb Artery Diseases (K-VIS ELLA) Registry is a multicenter observational study with retrospective and prospective cohorts of patients with lower extremity peripheral artery disease (PAD) undergoing endovascular treatment. In this study, we report the baseline characteristics of this retrospective cohort. SUBJECTS AND METHODS: In the present study we analyzed datasets of 3073 patients with 3972 target limbs from a retrospective cohort treated with endovascular therapy in 31 Korean hospitals...
July 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/28756079/-exercise-testing-new-guidelines
#20
Dany Michel Marcadet
The GERS (Exercise Rehabilitation and Sports Group of the French Society of Cardiology) has decided to update current guidelines regarding the practice of EKG stress tests. Since the last update dates from 1997, the GERS judged it necessary to integrate data from new works and advancements made in the last 20 years. Good clinical practices and safety conditions are better defined regarding the structure, location, material, staff competency, as well as convention with hospital structures. The diagnosis of coronary artery disease remains the principal indication for a stress test...
July 2017: La Presse Médicale
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