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https://www.readbyqxmd.com/read/28921476/expression-of-concern-to-role-of-physiotherapy-in-the-mobilization-of-patients-with-spinal-cord-injury-undergoing-human-embryonic-stem-cells-transplantation
#1
Geeta Shroff, Dipin Thakur, Varun Dhingra, Deepak Singh Baroli, Deepanshu Khatri, Rahul Dev Gautam
The Editors-in-Chief of Clinical and Translational Medicine are issuing an editorial expression of concern to alert readers that concerns have been raised regarding the ethics of this study [1]. Appropriate editorial action will be taken once this has been fully investigated. Geeta Shroff disagrees with this notice. Dipin Thakur, Varun Dhingra, Deepak Singh Baroli, Deepanshu Khatri and Rahul Dev Gautam have not responded to our correspondence about this article.
September 18, 2017: Clinical and Translational Medicine
https://www.readbyqxmd.com/read/28917286/intraoperative-3d-computed-tomography-spine-surgery
#2
REVIEW
Stephanie E Adamczak, Frank J Bova, Daniel J Hoh
Spinal instrumentation often involves placing implants without direct visualization of their trajectory or proximity to adjacent neurovascular structures. Two-dimensional fluoroscopy is commonly used to navigate implant placement, but with the advent of computed tomography, followed by the invention of a mobile scanner with an open gantry, three-dimensional (3D) navigation is now widely used. This article critically appraises the available literature to assess the influence of 3D navigation on radiation exposure, accuracy of instrumentation, operative time, and patient outcomes...
October 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28914720/effects-of-corrective-exercise-for-thoracic-hyperkyphosis-on-posture-balance-and-well-being-in-older-women-a-double-blind-group-matched-design
#3
Hyun-Jeong Jang, Lynne C Hughes, Duck-Won Oh, Suhn-Yeop Kim
BACKGROUND AND PURPOSE: The purpose of this study was to identify the effects of a corrective exercise for thoracic hyperkyphosis on posture, balance, and well-being in Korean community-dwelling older women. METHODS: Fifty women 65 years of age and older, recruited from 2 senior centers, participated in this study. Participants were assigned to either the experimental group (EG) or the control group (CG) on the basis of convenience of location, and 22 in each were analyzed...
September 13, 2017: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/28913395/simultaneous-bilateral-total-hip-arthroplasty-in-morquio-syndrome
#4
Imran Ilyas, Syed Kashif, Samar Rabbani, Husam A Alrumaih
A 16-year-old girl who had Morquio syndrome presented with severe bilateral hip pain and limited mobility because of bilateral hip osteoarthritis and fixed flexion deformities. She was wheelchair bound for the previous 6 months. Cervical spine flexion-extension views showed mild subluxation (<3 mm), and there was thoracolumbar spine kyphosis. Magnetic resonance imaging of the cervical and thoracolumbar spine showed hypoplasia of the odontoid and vertebral bodies, but no spinal cord compression. Bilateral cemented total hip arthroplasty was performed through a posterior approach under general anesthesia with fiberoptic intubation...
September 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/28906391/a-meta-analysis-of-the-preoperative-use-of-gabapentinoids-for-the-treatment-of-acute-postoperative-pain-following-spinal-surgery
#5
Bo Liu, Ruihe Liu, Lifeng Wang
BACKGROUND: Gabapentinoid drugs, which include gabapentin and pregabalin, play an established role in the management of neuropathic pain. However, whether preoperative administration of gabapentinoids has a beneficial role in controlling acute pain after spinal surgery is unknown. We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) to determine the efficacy and safety of the preoperative use of gabapentinoids (gabapentin and pregabalin) for the treatment of acute postoperative pain following spinal surgery...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28905003/an-immediate-effect-of-pnf-specific-mobilization-on-the-angle-of-trunk-rotation-and-the-trunk-pelvis-hip-angle-range-of-motion-in-adolescent-girls-with-double-idiopathic-scoliosis-a-pilot-study
#6
A Stępień, K Fabian, K Graff, M Podgurniak, A Wit
BACKGROUND: Impairment of spine rotation is a key concept in several theories explaining the pathogenesis and progression of scoliosis. In previous studies, a more limited range of motion in scoliotic girls compared to their non-scoliotic peers was noted. The Trunk-Pelvis-Hip Angle measurement is a test used to assess the range of motion in the trunk-pelvis-hip complex in the transverse plane. The aim of this study was to assess an immediate effect of Proprioceptive Neuromuscular Facilitation specific mobilization (mPNF) on the angle of trunk rotation and Trunk-Pelvis-Hip Angle range of motion in adolescent girls with double scoliosis...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28902101/early-ambulation-decreases-length-of-hospital-stay-perioperative-complications-and-improves-functional-outcomes-in-elderly-patients-undergoing-surgery-for-correction-of-adult-degenerative-scoliosis
#7
Owoicho Adogwa, Aladine A Elsamadicy, Jared Fialkoff, Joseph Cheng, Isaac O Karikari, Carlos Bagley
STUDY DESIGN: Ambispective cohort review. OBJECTIVE: To examine the effects of early mobilization on patient outcomes, complications profile, and 30-day readmission rates. SUMMARY OF BACKGROUND DATA: Prolonged immobilization after surgery can result in functional decline and an increased risk of hospital-associated complications. METHODS: We conducted an ambispective study of 125 elderly patients (>65 years) undergoing elective spinal surgery for correction of adult degenerative scoliosis...
September 15, 2017: Spine
https://www.readbyqxmd.com/read/28899825/long-term-performance-and-user-satisfaction-with-implanted-neuroprostheses-for-upright-mobility-after-paraplegia-two-to-14-year-follow-up
#8
Ronald J Triolo, Stephanie Nogan Bailey, Kevin M Foglyano, Rudi Kobetic, Lisa M Lombardo, Michael E Miller, Gilles Pinault
OBJECTIVE: To quantify the long-term (LT) (>2 years) effects of lower extremity (LE) neuroprostheses (NPs) for standing, transfers, stepping and seated stability after spinal cord injury. DESIGN: Single-subject design case series with participants acting as their own concurrent controls, including retrospective data review. SETTING: Hospital-based clinical biomechanics laboratory with experienced (>20 years in the field) research biomedical engineers, physical therapist and medical monitoring review...
September 9, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28895578/challenges-in-comprehensive-management-of-spinal-cord-injury-in-india-and-in-the-asian-spinal-cord-network-region-findings-of-a-survey-of-experts-patients-and-consumers
#9
H S Chhabra, S Sharma, M Arora
STUDY DESIGN: Online survey. OBJECTIVES: To understand the prevailing scenario of the comprehensive management of spinal cord injuries (SCI) in India and in the Asian Spinal Cord Network (ASCoN) region, especially with a view to document the challenges faced and its impact. SETTING: Indian Spinal Injuries Centre. METHODS: A questionnaire was designed which covered various aspects of SCI management. Patients, consumers (spinal injured patients discharged since at least 1 year) and experts in SCI management from different parts of India and the ASCoN region were approached to complete the survey...
September 12, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28885297/spinal-surgeons-opinions-on-pre-and-postoperative-rehabilitation-in-patients-undergoing-lumbar-spinal-fusion-surgery-a-survey-based-study-in-the-netherlands-and-sweden
#10
Reni M A van Erp, Jetse Jelsma, Ivan P J Huijnen, Mari Lundberg, Paul C Willems, Rob J E M Smeets
STUDY DESIGN: A cross-sectional survey in the Netherlands and Sweden. OBJECTIVE: To investigate Dutch and Swedish spinal surgeons' opinions on spinal fusion pre- and postoperative rehabilitation. SUMMARY OF BACKGROUND DATA: Lumbar spinal fusion surgery is increasingly provided in patients with chronic low back pain. No guidelines however exist for pre- and postoperative rehabilitation and it is unknown what opinions spinal surgeons currently have about pre- and postoperative rehabilitation...
September 6, 2017: Spine
https://www.readbyqxmd.com/read/28883437/alpha-subunit-dependent-glycine-receptor-clustering-and-regulation-of-synaptic-receptor-numbers
#11
A Patrizio, M Renner, R Pizzarelli, A Triller, C G Specht
Accumulation of glycine receptors at synapses requires the interaction between the beta subunit of the receptor and the scaffold protein gephyrin. Here, we questioned whether different alpha subunits could modulate the receptors' diffusion and propensity to cluster at spinal cord synapses. Using quantitative photoactivated localisation microscopy we found that alpha-1 and alpha-3 containing glycine receptors display the same α3:β2 stoichiometry and gephyrin binding. Despite these similarities, alpha-3 containing receptors are less mobile and cluster at higher density compared to alpha-1, with 1500 versus 1100 complexes µm(-2), respectively...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28880757/prospective-observational-study-of-single-or-multi-compartment-pressure-ulcer-prevention-cushions-prescaroh-project
#12
S Meaume, M Marty, D Colin
OBJECTIVE: In patients with reduced mobility, specialised pressure-relieving supports (mattresses, beds and cushions) are widely used to reduce or relieve the interface pressure between the skin and support surfaces to prevent incidence of pressure ulcers (PUs). The primary objective of these two observational studies was to assess the incidence of PUs in patients at high risk of PUs, seated in a wheelchair using a single- or multi-compartment air cushion. The level of patient satisfaction with the comfort and the views of the care team that used the air cushions were considered as secondary objectives...
September 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28880132/linking-spinal-cord-injury-rehabilitation-between-the-world-wars-the-r-tait-mckenzie-legacy
#13
John F Ditunno
Spinal cord injury (SCI) medicine emerged after World War II due to mass casualties, which required specialized treatment centers. This approach to categorical care, however, was first developed during World War I, led by pioneers R. Tait McKenzie and George Deaver, who demonstrated that soldiers disabled by paralysis could return to society through fitness/mobility, recreational and vocational training. McKenzie, a Canadian and the first professor of physical therapy in the US, influenced Deaver and military physicians in Britain, Canada, and the U...
September 7, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28880130/the-effects-of-semi-immersive-virtual-reality-therapy-on-standing-balance-and-upright-mobility-function-in-individuals-with-chronic-incomplete-spinal-cord-injury-a-preliminary-study
#14
Chang-Man An, Young-Hyun Park
Background Individuals with chronic incomplete spinal cord injury (iSCI) commonly face persistent balance or mobility impairments. Virtual reality (VR) therapy is a useful rehabilitation approach; however, little is known about its effects in individuals with chronic iSCI. Objective To investigate the effects of semi-immersive VR therapy on standing balance and upright mobility function in individuals with chronic iSCI. Methods Ten subjects with chronic iSCI underwent VR therapy 30 minutes a day, 3 days a week, for 6 weeks...
September 7, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28872428/community-based-physical-activity-and-wheelchair-mobility-programs-for-individuals-with-spinal-cord-injury-in-canada-current-reflections-and-future-directions
#15
Krista L Best, Kelly P Arbour-Nicitopoulos, Shane N Sweet
RATIONALE: A clear need has been identified to find strategies and opportunities, beyond services provided during rehabilitation, to enhance community-based mobility and leisure-time physical activity (LTPA) participation among members of the spinal cord injury (SCI) population. METHOD: This review of existing mobility and LTPA programs that are available for individuals with SCI in Canada reflects the authors' current knowledge of existing evidence-based and community-based programs...
September 5, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28870058/technologically-advanced-assessment-of-upper-limb-spasticity-a-pilot-study
#16
Federico Posteraro, Simona Crea, Stefano Mazzoleni, Mihai Berteanu, Ileana Ciobanu, Nicola Vitiello, Marco Cempini, Sabata Gervasio, Natalie Mrachacz-Kersting
BACKGROUND: Spasticity is a muscle disorder associated with upper motor neuron syndrome occurring in neurological disorders, such as stroke, multiple sclerosis, spinal cord injury and others. It influences the patient's rehabilitation, interfering with function, limiting independence, causing pain and producing secondary impairments, such as contractures or other complications. Due to the heterogeneity of clinical signs of spasticity, there is no agreement on the most appropriate assessment and measurement modality for the evaluation of treatment outcomes...
September 4, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28861038/alleviation-of-motor-impairments-in-patients-with-cerebral-palsy-acute-effects-of-whole-body-vibration-on-stretch-reflex-response-voluntary-muscle-activation-and-mobility
#17
Anne Krause, Eckhard Schönau, Albert Gollhofer, Ibrahim Duran, Anja Ferrari-Malik, Kathrin Freyler, Ramona Ritzmann
INTRODUCTION: Individuals suffering from cerebral palsy (CP) often have involuntary, reflex-evoked muscle activity resulting in spastic hyperreflexia. Whole-body vibration (WBV) has been demonstrated to reduce reflex activity in healthy subjects, but evidence in CP patients is still limited. Therefore, this study aimed to establish the acute neuromuscular and kinematic effects of WBV in subjects with spastic CP. METHODS: 44 children with spastic CP were tested on neuromuscular activation and kinematics before and immediately after a 1-min bout of WBV (16-25 Hz, 1...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28860068/protraction-of-neuropathic-pain-by-morphine-is-mediated-by-spinal-damage-associated-molecular-patterns-damps-in-male-rats
#18
Peter M Grace, Keith A Strand, Erika L Galer, Kenner C Rice, Steven F Maier, Linda R Watkins
We have recently reported that a short course of morphine, starting 10days after sciatic chronic constriction injury (CCI), prolonged the duration of mechanical allodynia for months after morphine ceased. Maintenance of this morphine-induced persistent sensitization was dependent on spinal NOD-like receptor protein 3 (NLRP3) inflammasomes-protein complexes that proteolytically activate interleukin-1β (IL-1β) via caspase-1. However, it is still unclear how NLRP3 inflammasome signaling is maintained long after morphine is cleared...
August 30, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28855792/addressing-neurodynamic-irritability-in-a-patient-with-adhesive-capsulitis-a-case-report
#19
Kevin Farrell, Katherine Lampe
BACKGROUND: Patients with adhesive capsulitis are commonly seen by physical therapists. Pain and limited shoulder motion from adhesive capsulitis have at times been linked to neural irritation. The purpose of this case is to describe the examination and intervention of a patient with adhesive capsulitis who appeared to have a coexisting, underlying neural irritation. This paper emphasizes how the neurological component must initially be identified and addressed for a successful outcome...
February 2017: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/28852357/influence-of-45s5-bioactive-glass-in-a-standard-calcium-phosphate-collagen-bone-graft-substitute-on-the-posterolateral-fusion-of-rabbit-spine
#20
Andrew J Pugely, Emily B Petersen, Nicole DeVries-Watson, Douglas C Fredericks
INTRODUCTION: Spinal fusion surgery is an effective but costly treatment for select spinal pathology. Historically iliac crest bone graft (ICBG) has remained the gold standard for achieving successful arthrodesis. Given well-established morbidity autograft harvest, multiple bone graft replacements, void fillers, and extenders have been developed. The objective of this study was to evaluate the in vivo efficacy and safety of two mineralized collagen bone void filler materials similar in composition...
2017: Iowa Orthopaedic Journal
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