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https://www.readbyqxmd.com/read/28299325/protective-effects-of-the-segmental-renal-artery-clamping-technique-on-ischemia-reperfusion-injury-in-db-db-diabetic-mice
#1
Chao Liang, Jundong Zhu, Chenkui Miao, Shangqian Wang, Lei Zhang, Pu Li, Zengjun Wang, Pengfei Shao
Renal ischemia-reperfusion (I/R) injury is inevitable in partial nephrectomy and other kidney surgeries, with a higher incidence in patients with renal insufficiency. This study aimed to investigate the protective effects of precise segmental renal artery clamping (SRAC) against renal I/R injury in db/db diabetic mice, compared with conventional renal artery clamping (RAC). Grape seed extract, a powerful free radical scavenger, was administered to diabetic mice for 4 weeks before operation in subgroups (30 mg/kg/d)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28288191/influence-of-tumor-size-on-oncological-outcomes-of-pathological-t3an0m0-renal-cell-carcinoma-treated-by-radical-nephrectomy
#2
Luyao Chen, Xin Ma, Hongzhao Li, Liangyou Gu, Xintao Li, Yu Gao, Yongpeng Xie, Xu Zhang
OBJECTIVE: To evaluate the prognostic significance of tumor size in pathological T3aN0M0 renal cell carcinoma (RCC) treated by radical nephrectomy. MATERIALS AND METHODS: Patients who underwent radical nephrectomy for sporadic RCC with pathological T3aN0M0 RCC at our institution between January 2006 and June 2015 were identified. The entire cohort was divided into two groups according to the cutoff of tumor size obtained from receiver operating characteristic (ROC) curve...
2017: PloS One
https://www.readbyqxmd.com/read/28281740/comparison-of-laparoendoscopic-single-site-less-and-multiport-laparoscopic-radical-nephrectomy-for-clinical-t1b-and-t2a-renal-masses
#3
Abd-El R Hassan, Omer A Raheem, Sean Berquist, Alp T Beksac, Aaron Bloch, Charles Field, Hak J Lee, Reza Mehrazin, Marc Holden, Michelle McDONALD, Zachary Hamilton, Michael Liss, Ithaar H Derweesh
BACKGROUND: To compare outcomes of Laparoendoscopic single-site surgery (LESS) and multiport laparoscopic (MPL) Radical Nephrectomy (RN) for clinical T1b/T2a renal masses, as concerns continue regarding suitability and benefit of LESS for larger renal masses. METHODS: Retrospective single-surgeon comparison of LESS- and MPL-RN between 7/2005 and 11/2014. 63 patients underwent LESS-RN (44 cT1b/19 cT2a); 133 underwent MPL (83 cT1b/50 cT2a). All patients were managed with a standardized care pathway...
March 10, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28270950/trends-of-partial-and-radical-nephrectomy-in-managing-small-renal-masses
#4
Ibrahim Khalid Al Saidi, Kholoud Saleh Alqasem, Saeda Turki Gharaibeh, Naim Z N Qamhia, Ibrahim Abukhiran, Ali Ahmad Al-Daghmin
OBJECTIVE: Use of partial nephrectomy (PN) for renal tumors appears to have relatively lower incidence rates in Jordan. We sought to characterize its trend at King Hussein Cancer Center for the last 10 years. MATERIAL AND METHODS: A retrospective review of our renal cell cancer data was performed. We identified 169 patients who had undergone surgery for renal tumors measuring ≤7 cm between 2005 and 2015. We characterized tumor size, pathology, type of surgery and clinical outcomes...
March 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28248049/-retroperitoneoscopic-radical-nephrectomy-with-inferior-vena-cava-thrombectomy
#5
D V Perlin, V P Zipunnikov, I N Dymkov, A O Shmanev
INTRODUCTION: Although laparoscopic radical nephrectomy has confidently established itself as the "gold standard" for treating renal cell carcinoma, reports on laparoscopic level II-III inferior vena cava (IVC) tumor thrombus thrombectomy are still lacking. MATERIALS AND METHODS: From September 2013 through April 2015, three patients with renal cell carcinoma and level II IVC tumor thrombi underwent laparoscopic radical nephrectomy with IVC thrombectomy using a retroperitoneal approach...
December 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28242987/renal-metastasis-and-dual-18-f-fluorodeoxyglucose-and-131-i-avid-skeletal-metastasis-in-a-patient-with-papillary-thyroid-cancer
#6
Prashanth Kulkarni, Pobbi Setty Radhakrishna Gupta Rekha, Meghana Prabhu, Sunil Hejjaji Venkataramarao, Nalini Raju, Naveen Hedne Chandrasekhar, Subramanian Kannan
Differentiated thyroid carcinoma (DTC) though usually behaves in an indolent manner, can have unusual metastatic presentation. Initial presentation of metastatic disease has been reported in 1-12% of DTC being less frequent in papillary (~2%) than in follicular (~10%) thyroid carcinoma. Renal metastasis from DTC is very rare. To our knowledge, only about 30 cases have been reported in the English literature to date. To make clinicians aware that management of such high-risk thyroid cancer frequently requires novel multimodality imaging and therapeutic techniques...
January 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28193294/myxoma-of-the-kidney-an-unusual-benign-renal-tumor-a-case-report
#7
Somuah Tenkorang, Youssef Kharbach, Jean-Paul Omana, Boubacar Efared, Soufiane Mellas, Mohammed Fadl Tazi, Mohamed Sekal, Taoufik Harmouch, Abdelhak Khallouk, Jamal Mohammed El Fassi, Jalal Eddine El Ammari, Moulay Hassan Farih
BACKGROUND: Myxomas are rare benign soft tissue tumors. The kidney is an unusual location for this tumor. For this reason, less than 15 cases of renal myxoma have been reported in the English literature. There are no specific clinical and radiological features reported for this tumor that allow a preoperative diagnosis enabling a conservative treatment. CASE PRESENTATION: We report another case of renal myxoma found in a 50-year-old Moroccan woman who presented with a right dull flank pain...
February 14, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28159494/compensatory-structural-and-functional-adaptation-after-radical-nephrectomy-for-renal-cell-carcinoma-according-to-preoperative-stage-of-chronic-kidney-disease-choi-dk-jung-sb-park-bh-jeong-bc-seo-si-jeon-ss-lee-hm-choi-hy-jeon-hg-j-urol-2015-oct-194-4-910-5
#8
Raman Jay, S B Jung, B H Park, B C Jeong, S I Seo, S S Jeon, H M Lee, H Y Choi, H G Jeon
PURPOSE: We investigated structural hypertrophy and functional hyperfiltration as compensatory adaptations after radical nephrectomy in patients with renal cell carcinoma according to the preoperative chronic kidney disease stage. MATERIALS AND METHODS: We retrospectively identified 543 patients who underwent radical nephrectomy for renal cell carcinoma between 1997 and 2012. Patients were classified according to preoperative glomerular filtration rate as no chronic kidney disease-glomerular filtration rate 90ml/min/1...
March 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28128912/robotic-assisted-radical-cystoprostatectomy-and-intracorporeal-ileal-conduit-urinary-diversion-for-a-kidney-transplant-recipient
#9
Peter A Caputo, Daniel Ramirez, Matthew Maurice, Ryan Nelson, Onder Kara, Ercan Malkoc, David Goldfarb, Jihad Kaouk
INTRODUCTION AND OBJECTIVES: Robotic assisted radical cystectomy (RARC) is an alternative to open radical cystectomy. As experience is gained with the RARC approach the technique is being applied to more complex surgical cases. We describe here our technique for RARC with intracorporeal ileal conduit urinary diversion for a renal transplant recipient. MATERIALS AND METHODS: The patient is a 60-year old man with high-grade muscle invasive bladder cancer. He has a history of renal failure due to polycystic kidney disease and received a deceased donor renal transplant in 2008...
January 27, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28011005/the-enduring-patency-of-primary-inferior-vena-cava-repair
#10
Neel A Mansukhani, George E Havelka, Irene B Helenowski, Heron E Rodriguez, Andrew W Hoel, Mark K Eskandari
BACKGROUND: Inferior vena cava repair after planned and unplanned venotomy is performed by either interposition bypass, patch venopasty, or lateral venorrhaphy and primary repair. Primary repair of the inferior vena cava avoids the use of foreign material and allows an all-autologous repair in an expeditious fashion. The purpose of this study was to demonstrate the utility of inferior vena cava repair, determine the degree of inferior vena cava stenosis, and examine clinical outcomes after primary repair...
December 20, 2016: Surgery
https://www.readbyqxmd.com/read/27919577/primary-cic-dux4-round-cell-sarcoma-of-the-kidney-a-treatment-refractory-tumor-with-poor-outcome
#11
Sébastien Bergerat, Philippe Barthelemy, Pascal Mouracade, Hervé Lang, Christian Saussine, Véronique Lindner, Didier Jacqmin
The CIC-DUX4 sarcoma is a subset of the undifferentiated small round cell sarcoma family, presently recognized as a new clinicopathological entity. It is a rare and highly aggressive tumor usually arising in the soft parts of the limbs and the trunk. Only a very few cases of primitive visceral CIC-DUX4 have been hitherto described. We report the case of a 29 year-old male patient with a primary CIC-DUX4 sarcoma of the kidney with lung metastasis. The outcome of the disease was rapidly unfavorable. Despite radical nephrectomy, the patient experienced an early local retroperitoneal recurrence associated with lung and liver metastases...
November 24, 2016: Pathology, Research and Practice
https://www.readbyqxmd.com/read/27889493/partial-vs-radical-nephrectomy-for-t1-t2-renal-masses-in-the-elderly-comparison-of-complications-renal-function-and-oncologic-outcomes
#12
Julie Y An, Mark W Ball, Michael A Gorin, Jiwon J Hong, Michael H Johnson, Christian P Pavlovich, Mohamad E Allaf, Phillip M Pierorazio
OBJECTIVE: To compare outcomes of partial nephrectomy (PN) and radical nephrectomy (RN) in patients 65 years and older. MATERIALS AND METHODS: Our institutional renal mass registry was queried for patients 65 and older with solitary cT1-T2 renal mass resected by PN or RN. Clinicopathologic features and perioperative outcomes were compared between groups. Renal function outcomes measured by change in estimated glomerular filtration rate (eGFR) and freedom from eGFR< 45 mL/min/1...
February 2017: Urology
https://www.readbyqxmd.com/read/27845279/-the-results-of-laparoscopic-partial-nephrectomy-depending-on-the-type-of-access-and-the-tumour-size
#13
R Naghiyev, S Imamverdiyev, O Sanli
Aim - retrospective comparative analysis of results of laparoscopic partial nephrectomy (LPN) depending on the type of access and the size of the tumor. The study included 170 patients undergoing LPN during the period from 2010 to 2015 years. Among the patients was 108 males (63.5%) and 62 women (36.5%) ranging in age from 17 to 80 years (average age 56,6±0.9 years). Depending on the type of access and the size of the tumor patients divided into 4 subgroups-154 patients who performed transperitoneal LRP, 16 patients undergoing retroperitoneal partial nephrectomy, 117 patients with tumor less than 4 cm and 53 patients with tumor more than 4 cm...
October 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27725235/histologic-abnormalities-in-non-neoplastic-renal-parenchyma-and-the-risk-of-chronic-kidney-disease-following-radical-nephrectomy
#14
Ricardo Brandina, Katia Ramos Moreira Leite, Emerson Pereira Gregório, Karen Barros Parron Fernandes, Miguel Srougi
OBJECTIVE: To assess the association of histopathological parameters in non-neoplastic renal parenchyma with the development of new-onset chronic kidney disease (CKD) after radical nephrectomy. PATIENTS AND METHODS: Data were extracted from 222 patients who underwent radical nephrectomy. The Modification of Diet in Renal Disease formula was used. The study end point was development of CKD, defined as an estimated glomerular filtration rate (eGFR) of less than 60 mL/min/1...
October 8, 2016: Urology
https://www.readbyqxmd.com/read/27575462/the-application-of-hem-o-lok-clips-tied-with-threads-to-improve-surgical-view-in-retroperitoneal-laparoscopic-surgery-for-renal-cell-carcinoma
#15
Chao Zhang, Fei Guo, Huiqing Wang, Chen Ye, Zhensheng Zhang, Bo Yang, Chuanliang Xu, Yinghao Sun
OBJECTIVE: To evaluate the feasibility of Hem-o-lok clips tied with threads to improve surgical view in retroperitoneal laparoscopic surgery for renal cell carcinoma. MATERIALS AND METHODS: Laparoscopic radical and partial nephrectomies performed by a single surgeon from May 2013 to April 2015 were reviewed. If Hem-o-lok clips tied with threads were applied to improve surgical view, the patient was recruited to the Hem-o-lok group. The other patients were recruited to the control group...
February 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27564277/clinical-significance-of-preoperative-neutrophil-to-lymphocyte-ratio-in-renal-cell-carcinoma
#16
Alper Otunctemur, Murat Dursun, Huseyin Besiroglu, Kutan Ozer, Ozan Horsanali, Emin Ozbek
INTRODUCTION: We investigated the prognostic significance of the neutrophil-to-lymphocyte ratio on tumor stage and Fuhrman nuclear grade in renal cell carcinoma. METHODS: The records of 432 patients with RCC who underwent radical or partial nephrectomy between 2005 and 2014 were retrospectively reviewed. Patients were classified as group lower tumor stage(T1 + T2) and higher(T3 + T4). As like tumor stage, Fuhrman nuclear grade were classified lower (G1+G2) and higher(G3+G4) too...
July 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27514504/laparoscopic-retroperitoneal-partial-nephrectomy-using-an-ergonomic-chair-demonstration-of-technique-and-matched-pair-analysis
#17
Jens J Rassweiler, Jan Klein, Alexandra Tschada, Ali Serdar Gözen
OBJECTIVES: To present the technique and long-term results of retroperitoneal laparoscopic partial nephrectomy (LPN), focusing on the impact of an ergonomic platform. PATIENTS AND METHODS: Between January 2000 and May 2016, 287 patients (193 men, 94 women) underwent LPN performed by four surgeons. The median (range) patient age was 59 (19-85) years, tumour size 3.1 (1-9) cm and PADUA score 7.3 (6-12). Access was retroperitoneal in 235 cases (82%). Since October 2010, we have used the ETHOS(™) chair (ETHOS(™) , Seattle, WA, USA) during excision of the tumour in 130 patients (45...
February 2017: BJU International
https://www.readbyqxmd.com/read/27505105/long-term-outcome-of-nephron-sparing-surgery-compared-to-radical-nephrectomy-for-renal-cell-carcinoma-%C3%A2-4-cm-a-matched-pair-single-institution-analysis
#18
Charis Kalogirou, Hendrik Fender, Patricia Muck, Valentin Hey, Markus Krebs, Hubertus Riedmiller, Daniel Vergho
PURPOSE: We investigated the long-term oncological and functional outcome of nephron-sparing surgery/partial nephrectomy (PN) versus radical nephrectomy (RN) for any renal cell carcinoma (RCC) ≥4 cm. PATIENTS AND METHODS: Between 1997 and 2013, we identified 128 patients undergoing PN for RCC ≥4 cm and matched this collective to 128 patients undergoing RN. We then compared overall survival (OS), cancer-specific survival (CSS), progression-free survival (PFS) and functional parameters in both groups...
2017: Urologia Internationalis
https://www.readbyqxmd.com/read/27461655/retroperitoneoscopic-versus-open-surgical-radical-nephrectomy-for-152-chinese-patients-with-large-renal-cell-carcinoma-in-clinical-stage-ct2-or-ct3a-a-long-term-retrospective-comparison
#19
Xuhui Zhu, Xiaoyong Yang, Xiaopeng Hu, Xiaodong Zhang
INTRODUCTION: To evaluate the feasibility, safety, and long-term efficacy of retroperitoneal laparoscopic radical nephrectomy for Chinese patients with a mean body mass index (BMI) of ≤24 and large renal cell carcinoma (RCC). MATERIALS AND METHODS: A long-term retrospective analysis of clinical data of 152 Chinese patients with a mean BMI of ≤24 and large RCC. Totally, 84 patients who underwent retroperitoneal laparoscopic radical nephrectomy (RPNx) for tumor size >7 cm (group 1) were compared with 68 patients, who underwent open radical nephrectomy (group 2) for tumor with similar size characteristics...
April 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/27446340/surgical-monotherapy-may-be-a-suitable-therapeutic-strategy-for-advanced-collecting-bellini-duct-carcinoma-a-case-report-and-literature-review
#20
Liang Zhu, Zijian Wang, Cizhong Pan, Ran Peng, Xiong Wei, Zhaohui Zhong
Collecting duct carcinoma (CDC), which is also known as Bellini duct carcinoma, accounts for less than 1% of all renal cell carcinoma, which has a poor prognosis. Predominantly, clinicians recognize this disease due to past experience and case reports, and a standard treatment is yet to be established. The present case report describes a 57-year-old male patient with CDC who was successfully treated with a left laparoscopic radical nephrectomy without any adjuvant therapy and compares the present patient's clinical presentation with previously reported cases...
August 2016: Experimental and Therapeutic Medicine
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